U.P.

TECHNICAL UNIVERSITY, LUCKNOW

   

Syllabus

1st , 2nd , 3rd and 4th Year
[Effective from session 2009-10]

BACHELOR OF PHARMACY 

1   

U.P. TECHNICAL UNIVERSITY LUCKNOW
STUDY AND EVALUATION SCHEME [Effective from the session : 2009-10]
Course: B.Pharm.

Year-I, Semester-I
S.N . Course Code PHARM111M PHARM111B PHARM112 PHARM113 PHARM114 PHARM115 PHARM116 PHARM111 P PHARM112P PHARM113 P PHARM114P PHARM115P Subject Name

Theory
Remedial Mathematics Or Remedial Biology Pharmaceutical Analysis-I Pharmaceutical Chemistry-I (Inorganic Pharm. Chem.) Pharmaceutics-I(General Pharmacy) Anatomy, Psysiology and Path physiology-I Professional Communication-I 1.

Period (Hours) L P 3 3 3 3 3 3 3 0 0 0 0 0 0 0

Sessional CT 15 10 15 15 15 15 15 TA 05 10 05 05 05 05 05 Tota l 20 20 20 20 20 20 20

Exam ESE 80 80 80 80 80 80 80

Subject Total 100 100 100 100 100 100 100

2. 3. 4. 5 6

Practical Day to Day Evaluation
7 8 9 10 11 Remedial Biology Pharmaceutical Analysis-I Pharmaceutical Chemistry-I (Inorganic Pharm. Chem.) Pharmaceutics-I(General Pharmacy) Anatomy, Physiology and Path physiology-I 0 0 0 0 0 18 4 4 4 4 4 20 ------------20 20 20 20 200 80 80 80 80 800 100 100 100 100 1000

T.A- Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE- Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively.                                    2     

 

 

 

 

 

 

 

 

 

U.P. TECHNICAL UNIVERSITY LUCKNOW
STUDY AND EVALUATION SCHEME [Effective from the session : 2009-10]
Course: B.Pharm.

Year-I, Semester-II
S.N . Course Code Subject Name Period (Hours) Sessional Exam Subject Total

Theory
1. 2. 3. 4. 5 PHARM121 PHARM122 PHARM123 PHARM124 PHARM125 PHARM121 P PHARM122P PHARM124 P Physical Chemistry Pharmaceutical Chemistry-II (Organic Chemistry-I) Anatomy, Physiology and Path physiology-II Computer Fundamentals & Programming Pharmaceutical Biostatistics

L 3 3 3 3 3

P 0 0 0 0 0

CT 15 15 15 15 15

TA 05 05 05 05 05

Tot al 20 20 20 20 20

ESE 80 80 80 80 80 100 100 100 100 100

Practical Day to Day Evaluation
6 7 8 Physical Chemistry Pharmaceutical Chemistry-II (Organic Chemistry-I) Computer Fundamentals & Programming 0 0 0 15 4 4 4 12 --------20 20 20 160 80 80 80 640 100 100 100 800

T.A- Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE- Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. 

             

3   

Year-II.P. 2. 5 6 Course Code PHARM231 PHARM232 PHARM233 PHARM234 PHARM235 PHARM236 PHARM231 P PHARM233P PHARM234 P PHARM235 P Subject Name Theory Pharmaceutics-II (Unit Operation-I) Pharmaceutical Jurisprudence & Ethics Pharmacognosy-I Pharmaceutical Chemistry-III (Organic Chemistry-II) Pharmaceuitics-III (Community Pharmacy) Anatomy. 1. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2010-11] Course: B.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE. Physiology and Path physiology-III Pharmaceutics-II (Unit Operations-I) Pharmacognosy-I Pharmaceutical Chemistry-III (Organic Chemistry-II) Pharmaceutics-III (Community Pharmacy) Period (Hours) L P 3 3 3 3 3 3 --------------------- Sessional CT 15 15 15 15 15 15 TA 05 05 05 05 05 05 Total 20 20 20 20 20 20 Exam ESE 80 80 80 80 80 80 Subject Total 100 100 100 100 100 100 Practical Day to Day Evaluation 7 8 9 10 ------------18 4 4 4 4 16 --------------20 20 20 20 200 80 80 80 80 800 100 100 100 100 1000 T.Pharm.Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. N.A. 3. 4.U.                  4      . Semester-III S.

Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2010-11] Course: B.Pharm.A.P. Semester-IV S. 1. 5 Course Code PHARM241 PHARM242 PHARM243 PHARM244 PHARM245 PHARM241 P PHARM242P PHARM243 P PHARM244 P Subject Name Theory Pharmaceutics-IV (Unit Operation-II) Pharmaceutical Microbiology Pharmacognosy-II Pharmaceutical Analysis-II Anatomy. Physiology and Pathophysiology-IV Pharmaceutics-IV (Unit Operations-II) Pharmaceutical Microbiology Pharmacognosy-II Pharmaceutical Analysis-II Period (Hours) L P 3 3 3 3 3 -----------------Sessional CT 15 15 15 15 15 TA 05 05 05 05 05 Tot al 20 20 20 20 20 Exam ESE 80 80 80 80 80 100 100 100 100 100 Subject Total Practical Day to Day Evaluation 6 7 8 9 ------------15 4 4 4 4 16 --------------20 20 20 20 180 80 80 80 80 720 100 100 100 100 900 T. 2. 3. Year-II. 4. N.                     5    .U.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE.

Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. 4. S. N.A. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2011-12] Course: B.P. 3. Semester-V Period (Hours) L P 3 -----------------Sessional CT 15 15 15 15 15 TA 05 05 05 05 05 Tot al 20 20 20 20 20 Exam ESE 80 80 80 80 80 100 100 100 100 100 Subject Total Theory Pharmaceutical Chemistry-IV (Biochemistry) Pharmaceutics3 V(Pharmaceutical Technology-I) Pharmacology-I 3 Pharmaceutical ChemistryV(Medicinal Chemistry-I) Pharmaceutics-VI (Physical Pharmacy) Pharmaceutical Chemistry-IV (Biochemistry) Pharmaceutics-V (Pharmaceutical Technology-I) Pharmacology-I Pharmaceutical Chemistry-V (Medicinal Chemistry-I) Pharmaceutics-VI (Physical Pharmacy) 3 3 Practical Day to Day Evaluation 6 7 8 9 10 ----------------15 4 4 4 4 4 20 --------------------20 20 20 20 20 200 80 80 80 80 80 800 100 100 100 100 100 1000 T.U. 1.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE.Pharm.         6    . 2. 5 Course Code PHARM351 PHARM352 PHARM353 PHARM354 PHARM355 PHARM351 P PHARM352P PHARM353 P PHARM354 P PHARM355P Subject Name Year-III.

1.U. 5 6 Course Code PHARM361 PHARM362 PHARM363 PHARM364 PHARM365 PHARM366 PHARM361 P PHARM362P PHARM363 P PHARM364 P Subject Name Theory Pharmaceutical Chemistry-VI (Medicinal Chemistry-II) Pharmaceutics-VII (Pharmaceutical Technology-II) Pharmacology-II Pharmacognosy-III Professional Communication-II Environment & Ecology Period (Hours) L P 3 ---3 3 3 3 3 -----------------Sessional CT 15 15 15 15 15 15 TA 05 05 05 05 05 05 Total 20 20 20 20 20 20 Exam ESE 80 80 80 80 80 80 Subject Total 100 100 100 100 100 100 Practical Day to Day Evaluation 7 8 9 10 Pharmaceutical Chemistry-VI (Medicinal Chemistry-II) Pharmaceutics-VII (Pharmaceutical Technology-II) Pharmacology-II Pharmacognosy-III ------------4 4 4 4 ------------20 20 20 20 80 80 80 80 100 100 100 100 18 16 --200 800 1000 T. 4.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE.Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. Semester-VI S. 2. 3. N. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2011-12] Course: B. Year-III.Pharm.                                             7    .P.A.

5 Course Code PHARM471 PHARM472 PHARM473 PHARM474 PHARM475 PHARM471 P PHARM472P PHARM473 P PHARM475 P PHARM476P Subject Name Theory Pharmaceutical Analysis-III PharmaceuticsVIII(Biopharmaceutics & Pharmacokinetics) Pharmacology-III Pharmaceutical Chemistry-VI (Medicinal Chemistry-III) Pharmacognosy-IV Period (Hours) L P 3 3 3 3 3 -----------------Sessional CT 15 15 15 15 15 TA 05 05 05 05 05 Tot al 20 20 20 20 20 Exam ESE 80 80 80 80 80 100 100 100 100 100 Subject Total Practical Day to Day Evaluation 6 7 8 9 10 Pharmaceutical Analysis-III Pharmaceutics-VIII (Biopharmaceutics & Pharmacokinetics) Pharmacology-III Pharmacognosy-IV Report on Industrial Visit 15 16 --180 ------------4 4 4 4 ------------20 20 20 20 80 80 80 80 100 820 100 100 100 100 100 1000 T.U. 1.P. N. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2012-13] Course: B. 2. Semester-VII S.Pharm.Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively.           8    . 3. 4.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE.A. Year-IV.

1. Year-IV. Semester-VIII S. N.Pharmaceutical Marketing Or (E).Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE.Clinical Pharmacy & Drug Interactions Or (D). Quality Assurance & Validation ------- 4 4 --- --- 20 20 80 80 100 100 15   8 -- -- 140 560 700 T.Novel Drug Delivery Systems Or (G)-GMP.Clinical Pharmacy & Drug Interactions Or (D).Pharmaceutical Packaging Or (F).Standardization of Herbal Drugs Or (B).Pharmaceutical Packaging Or (F). Quality Assurance & Validation Practical Day to Day Evaluation PHARMNatural Products 6 482 P PHARMProject on Elective:7 485P A). 3. 5 Course Code PHARM481 PHARM482 PHARM483 PHARM484 PHARM485 Subject Name Theory Pharmaceutical Biotechnology Natural Products Pharmaceutical Industrial Management Hospital Pharmacy Period (Hours) L P 3 3 3 3 3 ------------------ Sessional CT 15 15 15 15 15 Exam Tot al 20 20 20 20 20 Subject Total 100 100 100 100 100 TA 05 05 05 05 05 ESE 80 80 80 80 80 Elective (A).Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. 4.A.Drug Design Or (C ).Pharmaceutical Marketing Or (E). TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2012-13] Course: B.Standardization of Herbal Drugs Or (B). 2.U.P.Pharm.Novel Drug Delivery Systems Or (G)-GMP. 9    .Drug Design Or (C ).

Subtraction 3. S. distance between two parts. 4. 3. 2. Trigonometric function of Integral calculus. New Delhi 5. Integral calculus . Statistical Methods. Chain Rule. Unit-IV: 1. intercept form in normal. Cramer’s Rule Algebra of matrics-1. Unit-III: Differential Calculus1. straight line. S. locus of points. Sultan Chand and Co. Multiplication 4. and particular Integral (Xneax. NCERT Publication Vol. Loney. A textbook of Mathematics for XI-XII Students. Trignometric ( sin/ cos ex ) BOOKS RECOMENDED 1. Definition and formulation of differential calculus. Addition 2. Unit-V: Linear differential equation of order greater than one with constant coefficient complimentary function. 3. Narayan Shanti. 10    . Inverse of matrices Simultaneous equation by matrices.L “Plane Trigonometry” AITBS Publishers.L “The elements of coordinate geometry” AITBS Publishers. Standard form of Integral calculus 2. Parametric rule. I-IV. area of triangle. Gupta S.SEMESTER I PHARM-IIIM REMEDIAL MATHEMATICS Unit-I: Algebra: Equations reducible to quadratics. Limit and function 2. Rules of standard form of differential calculus. Loney.. 4. Partial fraction of Integral 3. Sultan Chand & Co.P. Unit-II: Certain co-ordinates.

trypanosoma. bark. wood. Basic concept of molecular biology (DNA.. different types of plant tissues and their functions. Vishal Mehta. modification of stems and roots. house fly. taenia.6. ascaris. leaf. mitosis and meiosis. plasmodium. 10. Pothishala Pvt. [04] [08] PHARM-IIIP 11    . Pothishala Pvt. Narayan Shanti. Shyamlal Charitable Trust.. oxyuris and ancyclostoma. [12] Unit-IV Plant cell: Its structure and non living inclusions. Differential calculus . 8. [08] Unit-II General structure and life history of insects like mosquito. Patkar “ Comprehensive remedial mathematics”. Ltd. Prasad Gorakh Text book on differential calculus. stem. Allahabad. PHARM-IIIB REMEDIAL BIOLOGY THEORY Unit-I:General survey of Animal Kingdom. Prasad Gorakh Text book on integral calculus .RNA) Unit-V Methods of classification of plants. Allahabad. New Delhi. schistosoma. Ltd. Structure and life history of parasites as illustrated by amoeba. flower. [08] Unit-III Morphology and histology of root. Shyam. fruit and seed. “ Remedial Mathematics for Pharmacy’. 9.entamoeba. mites and silk worm. 7.

C. HendersonHasselbach equation. Note: There shall be no University Examination for Remedial Biology Practical. BOOKS RECOMMENDED 1. Delhi. role of solvent. Gross identification of slides of structures and life cycle of lower plants/animals mentioned in theory. law of mass action. preliminaries and definitions. [06] Unit-II: Acid Base Titrations: Acid base concepts. 2.REMEDIAL BIOLOGY PRACTICAL PRACTICAL 1. theory of indicators. “ Botany for Degree students” Oxford. Structure of human parasites and insects mentioned in theory with the help of specimens. relative strengths of acids and bases. use and type of microscopes. Fahn “Plant Anatomy” Aditya Books Private Limited. Care. common-ion effect. neutralization curves. buffer solution. New Delhi. PHARM –112 PHARMACEUTICAL ANALYSIS-1 THEORY Unit-1 : Significance of quantitative analysis in quality control different techniques of analysis. Dutta A. polyprotic system. 3. 4. Marshall & Williams “Text Book of Zoology” CBS Publishers & Distrubutors. Morphology of plant parts indicated in theory. pH. microscopic examination of stem. hydrolysis of salts. root and leaf of monocot and dicot plants. primary and secondary standards. mixed indicators. ionization. 3. precision and accuracy. Preparation. choice of indicators. 5. Fundamentals of volumetric analysis. methods of expressing concentration. 6. 4. Weiz. Morphology of plant parts indicated in theory. [10] Unit-III: Oxidation reduction Titrations: 12    . ionic product of water. Paul B “Laboratory Manual in Science of Biology” Mc Graw-hill book company. acid base indicators. 2.

should also be covered. potassium dichromate. Standardization of analytical weights and calibration of volumetric apparatus. supersaturation. methods of weighing. redox indicators. titrations involving ceric sulphate. Acid Base Titrations : Preparation and Standardization of acids and bases. Some exercises related to determinations of oxidizing & reducing agents. digestion. Oxidation Reduction Titrations : Preparation & standardization of some redox titrants e. iodine solution and ceric ammonium sulphate. organic precipitants. weights. 2. redox reactions. Unit-V : Gravimetric Analysis: Precipitation techniques. Exercises involving potassium iodate. washing of the precipitate.g.1 PRACTICAL The students should be introduced to the main analytical tools through demonstration. strengths and equivalent weights of oxidizing and reducing agents. filter papers and crucibles.g.Concepts of oxidation and reduction. temperature and solvent upon the solubility of precipitate. coprecipitation. some official assay procedures. specific examples like barium as barium sulphate. potassium permanganate. Volhard’s method and Fajan’s method. care & use of balance. Ignition. solubility products. iodimetry and iodometry. effect of acids. 13    . The students should also be acquainted with the general apparatus requiring various analytical procedures. Gaylussac method. They should have a clear understanding of a typical analytical balance. thermogravimetric curves. e. solubility products. the colloidal state. [10] Unit-IV: Precipitation Titrations: Precipitation reactions. theory of redox titrations. [08] [06] PHARM-II2P PHARMACEUTICAL ANALYSIS . oxidation reduction curves. boric acid. iodine. some exercises related with determination of acids and bases separately or in mixture form. post-precipitation. Mohr’s method. potassium iodate. mercuric nitrate indicators. potassium bromate. potassium bromate. potassium permanganate. and errors in weighing. 1. Argentometric titrations and titrations involving ammonium or potassium thiocyanate. 3. filtration. sodium thiosulphate etc. aluminium as aluminium oxide. the requirements of a good balance.

Conners K. 2. Denny R. Cambridge. uses.. Jeffery G. BOOKS RECOMMENDED : 1. 5.H. “Vogel’s Textbook of Quantitative Chemical Analysis”. Volhards and Fajan’s methods. CBS Publishers & Distributors 6. PHARM – 113 PHARMACEUTICAL CHEMISTRY-1 (INORGANIC PHARMACEUTICAL CHEMISTRY) Unit-I A. Sources of impurities & their control.. Silver nitrate).Thomas M. Barnes J. An outline of methods of preparation. of the following classes of inorganic pharmaceuticals included in Indian Pharmacopoeia. 5. tests of purity and identification and special tests. Mendhanm J. if any. (1996) Gases and Vapors : Inhalants (Oxygen). astringents(Zinc oxide..B. Wiley Inter-science. 4. titrations according to Mohr’s. Beckett. Vol. British Pharmacopocia. and Stenlake. kaolin). Anaesthetics( Nitrous oxide).H.. Potassium permanganate.C. arsenic. 3. The Pharmacopoeia of India. Gravimetric Analysis : Preparation of gooch crucible for filtration and use of sintered glass crucible. 14    . heavy metals. Alexeyev V. University Press. titanium dioxide. Zinc Sulphate) and anti infectives (Boric Acid. Precipitation Titrations: Preparation and standardization of titrants like silver nitrate and Ammonium thiocyanate. Her Majesty’s Stationary Office. sources of impurities.. The Atherden Press of the University of London.D. Determination of water of hydration. phosphoric acid). Povidone Iodine. limit test for iron. water for injection and sterile water for injection).A. A. talc.. Hydrogen peroxide. Pharmaceutical aids and necessities: water (purified water. acids and bases (Sodium hydroxide. Pearson Education Asia. “Quantitative Analysis”. Iodine. J. lead. I&II. “A Text book of Pharmaceutical Analysis”. chloride & sulphate B. some exercise related to gravimetric analysis should be covered.4. pharmaceutical acceptable glass. Topical Agents : Protectives (Calamine. Practical Pharmaceutical Chemistry.

Magnesium oxide{ light and heavy}. Calcium carbonate. [08] [08] [08] PHARM-113P PHARMACEUTICAL CHEMSITRY-I (INORGANIC PHARMACEUTICAL CHEMISTRY) List of Experiments 1. Light Kaolin. Magnesium trisilicate ). antioxidants (Sodium metabisulphite). Aluminium sulphate Miscellaneous Agents: Expectorants (Ammonium chloride. Unit-II:Gastrointestinal Agents : Acidifying agents (Dilute Hydrochloric acid). Sodium dihydrogen phosphate. Potassium Iodide). sodium acetate. sulphate. potassium chloride. protective and adsorbents( Activated Charcoal. magnesium chloride). acid-base balance & combination therapy( Calcium chloride. Aluminium hydroxide. Magnesium hydroxide. Ferric Ammonium citrate).anti-caries agents (Sodium fluoride). mineral supplements (Cu. measurement of activity. clinical application and dosage. cathartics ( disodium hydrogen phosphate. To perform limit test of chloride. of Labs 5 15    . antacids(Bismuth subcarbonate. Cr. Iron and haematinics(Ferrous fumarate.hazards and precautions. Ferrous gluconate. Mn. Sodium thiosulphate).cellular electrolytes : Physiological ions. Calcium lactate. Magnesium carbonate{ light and heavy}. Unit-V Inorganic Radio-Pharmaceuticals: Nuclear radio pharmaceuticals.study of such compounds used in therapy including poison antidotes(Calcium folinate. Co-ordination compounds and complexation. Heavy metal and No. I). sodium chloride. Sb. Calcium gluconate. Zn. S. Calcium levulinate. Iron. Magnesium sulphate and other Magnesium [08] compounds). Electrolytes used for replacement therapy. Ferrous sulphate. sodium bicarbonate. Cationic and anionic components of inorganic drugs useful for systemic effects. Unit-IV : Essential and Trace Elements : Transition elements and their compounds of pharmaceutical importance. standards and units of activity. methods of obtaining.Dental Products : Dentrifices. [08] Unit-III : Major intra and extra. nomenclature.

M. ball mill. C. surfactants antioxidants. T and Wilson. Preparation of following compounds:Boric acid Magnesium sulphate Heavy magnesium carbonate Calcium Carbonate Alum Zinc sulphate BOOKS RECOMMENDED : 1..et. Soine. Atherden L.H. C. various methods & equipments employed for size separation e. 4. USP & International Pharmacopoeia. sieving. Medicinal & Pharmaceutical Chemistry”. Bentley and Drivers’ “Text Book of Pharmaceutical Chemistry”. laws & factors affecting energy requirements.. fluid energy mill & disintegrator. J. Block. flavouring & sweetening agents. Discher. 7 3 PHARM – 114 PHARMACEUTICS.g. “Inorganic. BP. Oxford University Press. Pharmacopoceia of India. Cosolvents. & their applications. waveland press. elutriation methods. 1996 edition. Roche. preservatives. for size reduction different methods of size reduction. introduction to pharmacopoeias with special reference to IP. E. 2.Principles and laws Governing size reducts factors affecting size reduction. Lea & Febiger. Pharmaceutical Additives : Colouring.al Modern Inorganic Pharmaceutical Chemistry. scope of pharmacy. principles. cyclone separator.1 (GENERAL PHARMACY) Unit-I History of Pharmacy : Origin & development of pharmacy. Unit-II Size Reduction : Definition. London. 3. Salt analysis 3.arsenic in the given sample.A.. study of hammer mill. 2. [06] 16    [04] [03] . sedimentation.

Aromatic Ammonia spirit BP 17    . BP. inhalations and powders. [03] Introduction to Pharmaceutical Dosage Forms: A brief theory of : Solutions. calculation of doses for infants. Strong Ammonium Acetate solution BP c) Syrups 1.reducing recepercentage solutions. Camphor Water BP 3.Unit-III : Pharmaceutical calculations : Posology. Rose Water NF b) Solutions 1. maceration & their modifications. elixirs. syrups. spirits. aromatic waters. mucilages. Unit-V Mixing: Theory of mixing. study of infusion. Aromatic Elixirs USP/NF e) Spirits 1. Chloroform water BP 2. liniments. paints. applications in the preparation of tinctures & extracts. digestion. glycerins. decoction. percolation. Unit-IV Extraction & Galenicals: Extraction processes. USP/NF. a) Aromatic Waters 1. adults and elderly patients. pastes. solid-solid. alcohol dilution. mixtures. alligation. Factors affecting selection of extraction processes. Simple syrup BP/USP/IP d) Elixirs 1. lotions. proof spirit. [07] [07] [10] PHARM-114P PHARMACEUTICS-I (GENERAL PHARMACY) I : Preparation of following classes of Pharmaceutical dosage forms (involving the use of calculations in metrology) as official in IP. solid-liquid & liquid-liquid mixing equipments. Enlarging and reducing receipes. mouth washes. Lysol solution IP 2.

Absorbable dusting powder USP/N g) Lotions 1. “Theory and Practice of Industrial Pharmacy”. The Controller of Publications. Pharmacopoeia of India. Liquorice liquid extract BP. Benzoin Inhalation BP .. ORS Powder IP 2.L. 4. Compound benzoin tincture BP 4.A. British Pharmacopoeia. Lea and Febiger. Turpentine liniment BP i) Mucilage j) Glycerins k) Inhalation l) Tinctures & Extracts 1. Carter S.A and Kanig J. Calamine lotion IP 2. Amino benzoic acid lotion BP h) Liniments 1. 2. CBS Publishers. Lachman L. 5. Cambridge. Solid-Solid mixing. “Bentley’s Text Book of Pharmaceutics”. “Cooper and Gunn’s Tutorial Pharmacy”.J. II: Experiments to illustrate principles of size reduction using Ball Mill. Effect of size of balls. III: Experiments to illustrate mixing efficiency.. New Delhi. number of balls and time on the efficiency of ball mill. ELBS Bailliere Tyndall. Methyl salicylate liniment BP 2.f) Powders 1.Liberman H. Strong Ginger tincture BP 5. Her Majesty’s Stationary Office. 6. Rawlins E. BOOKS RECOMMENDED: 1. Infusion of Tea 2. CBS Publishers. Cooper and Gunn’s Dispensing for Pharmaceutical Students. 3. 18    1. University Press. Delhi. Delhi. Kaolin Poultice BP 1. Starch Mucilage IP 1.. Decoction of Senna 3.

epithelial. specification for drinking water. connective. I & II. Introduction to human body & organisation of human body. Churchill Livingstone. erythopoesis. physiology of skeletal muscle contraction. c. types of movements of joints. [08] Unit-II Skeletal system Structure. PHARM-115 ANATOMY PHYSIOLOGY & PATHOPHYSIOLOGY -I Unit –I a. Functional & structural characteristics of cell. Vol. 9. their treatment & prevention. 8. Mack Publishing Co. Pennsylvania. Unit-IV Haemopoietic system : Composition & function of blood & its elements. blood coagulation.. Classification of joints. Remington – “The science and practice of pharmacy” Vol. energy metabolism. muscle tone. neurotransmission. muscle and nerve. [08] [08] [08] [08] 19    . types of muscle contraction. United States Pharmacopoeia (National Formulary). b) Classification of food requirements : Balanced diet.E. I & II.. Structural & functional characteristics of tissues. composition & functions of skeleton. blood groups. Aulton.7. b. Detailed structure of cell membrance & physiology of transport process. Unit-III Anatomy & physiology of skeletal & smooth muscle. M. Text Book of Pharmaceutics. Unit-V a) Concepts of health & disease: Disease causing agents & prevention of disease. Nutritional deficiency disorders.

basic understanding of Electrocardiogram – PQRST waves and their significance.Indirect. Preposition. Ranade VG. Hall JE. “Text Book of Practical Physiology”. Tenses.S.R. 6. Direct. Samson Wright’s Applied Physiology.B. Parmar N. 4. 3. Study of human skeleton.L. C. Guyton AC. D. and E. Keele.PHARM-II5P HUMAN ANATOMY. Niel.C. Chatterjee C. PHYSIOLOGY & PATHOPHYSIOLOGY -I PRACTICAL 1. 3. Harper & Row Publishers. “Health Education & Community Pharmacy” CBS Publishers. Ross & Wilson “Anatomy & Physiology in Health & Illness”. Delhi. WB Saunders Company.H.. [12] 20    . New Delhi. Estimationof haemoglobin in blood. 5. Recording of body temperature. Pune. Pune Vidyarthi Griha Prakashan. 8. “Atlas of Normal Histology” – Lea & Febiger Philadelphia. Medical Allied Agency. Count. 2. Articles. Shalya Subhash “Human Physiology” CBS Publishers & Distributors.C. BOOKS RECOMMENDED: 1. Calcutta.S. Total leucocyte count. Churchill Livingstone. “Human Physiology”. speech. PHARM-116 PROFESSIONAL COMMUNICATION-I UNIT-I English Grammar Parts of speech. 2. pulse rate and blood pressure. E and Joels N. Determination of bleeding time. 4. clotting time..A. R. 9. “Text book of Medical Physiology”. Tortora GJ.C. Oxford University Press. Active-Passive voice. 7. Microscopic study of different tissues. & Anagnodokos NP “Principles of Anatomy & Physiology”. Difore S.

. Robbins. Importance of non-verbal communication. UNIT-V Personality types. “High School Grammar and Composition”. pauses. S.Tips. stresses. S “Organisational Behaviour” 21    . Chand & Co. Decision making Motivation Attitude Thinking [06] [06] [08] [08] BOOKS RECOMMENDED 1. non words. eye contact for small & large groups. Role plays. voice modulation. . 2. Wren P. debates. Précis and Essay writing Comprehension Speed reading.C and Martin H. UNIT-IV Presentation techniques.UNIT-II Letter writing. UNIT-III Working on accent neutralisation. scanning & swimming.

heat of neutralisation. absolute temperature scale. acid base and enzyme catalysis. component. phase rule (excluding derivation). Adsorption : Freurdlich and Gibbs adsorption Isotherms. [08] [08] [08] 22    . Bomb calorimeter. theory of strong elecrolytes (Debye Huckle theory). crystal diffraction. theory of buffers. bond energies. Millers indices. colligative properties. first and second order reaction. Thermo chemistry : Definition & conventions. Physical properties of crystals. Electro chemistry : Faraday’s laws of Electrolysis. third and zeroth law. heat of solution. Hittorfs theoretical device. molar & equivalent conductivity and its variation with dilution.SEMESTER-II PHARM-121 PHYSICAL CHEMISTRY Unit-I 1. Arrhenius theory. pH : determination of PH buffers. characteristics of homogenous and heterogeneous catalysis. dipole moment) and chemical constituents. parachor. refractive index. Kirchoffs equation. viscosity. 11. 7. 2. 8. solutions of gases in liquids. Thermodynamics : Fundamentals. Unit-V 10. 3. deviation from ideal behaviour and explanation. Phase equilibria : Phase. Joule-Thompson’s effect. Solutions : Ideal and real solutions. Chemical kinetics : Zero. Transport number & migration of ion. degree of freedom. optical rotation. [08] Unit-IV 9. Hess law of constant summation. heat of combustion. Unit-III 6. The liquid state : Physical properties (surface tension. degree of ionisation & Ostwald dilution law. Electric conductance & its measurement. Amorphous and crystalline solids : geometry & symmetry of crystals. Kohlrausch law. rheochor. types of crystals. Langmuir theory of adsorption. 5. Unit-II 4. complex reactions. heat of reaction. elementary idea of reaction kinetics. second. Behaviour of gases : Kinetic theory of gases. first. heat of formation.

2.P. hybridization. & Bahl Arun. Tuli G. and Prabartak. Calcutta. J. Determination of rate constant of simple reaction.. Garland. atomic orbital. Determination of partition co-efficient.D. Chand & Co. NaCI-H2O system). & Lewis D. Macmillan Education. 4.E. Bahl B. Negi A. & Anand S. Determination of surface tension. 4. KI-H2O. pH determination by different methods.“Textbook of Physical Chemistry” Wiley Eastern Ltd. Determination refractive index of given liquids. Haltone Limited. C.K.W. 5.C.Cooling curves & Phase diagrams for one & two component system involving eutectics.I) Unit-I Structure and Properties : Atomic Structure. PHARM-122 PHARMACEUTICAL CHEMISTRY-II (ORGANIC CHEMISTRY. Glasstone S. MC Graw Hill Book Co. 3. BOOKS RECOMMENDED: 1. 5. 2.. 7. Pali S.D. Distribution law & application to solvent extraction. Atkins P & Paula. molecular orbital. congruent & incongruent melting point (examples-water. D. verify Ostwald dilution law and perform conductometric titrations. Practical Physical Chemistry. 6.S.. Elements of Physical Chemistry.S. [08] PHARM-I2IP PHYSICAL CHEMISTRY PRACTICAL 1. sulphur. Shoemaker. S. Experiments of Physical Chemistry. 23    . 3. Essential of Physical Chemistry. “Atkins Physical Chemistry” Oxford University Press. Determination of specific rotation of sucrose at various concentrations and determine the intrinsic rotation.D.R. S. Determination of cell constant. 6. Determination of solubility. 8.. 9. Determination of viscosity.

Purification of solvents like Benzene. acetylation. orientation of aromatic substitution. Stereochemistry including optical activity. reduction & oxidation. Synthesis of following compounds Picric acid Aniline Acetanilide Aspirin Hippuric acid 24    6 4 5 . Unit-III Important methods of preparation. [08] [08] [08] [08] [08] PHARM-I22P PHARMACEUTICAL CHEMISTRY –II (ORGANIC CHEMISTRY-I) SUGGESTED LIST OF PRACTICALS 1. alkynes & dienes. 2. hydroxy acids.sigma & Pi bond. their preparation &synthetic application. aryl halides. Unit-II Isomerism. di & tricarboxylic acids. geometrical isomerism. Identification of elements and functional groups in given sample. phenols.Grignard reagent. amines (aliphatic & aromatic). Unit-V Aldehydes and ketones (aliphatic & aromatic). reactions with special reference to mechanism of the following classes of compounds: Alkanes. carboxylic acids & their derivatives. Synthesis of compounds involving benzoylation. electrovalent and co-ordinate bond. acetone and preparation of absolute alcohol. resonance. specification of configuration and conformational analysis. stereoisomerism. chloroform. Organometallic Compounds. Alcohols. aromatic character. organolithium compounds. free radical substitution reaction. alkyI halides. alkenes. structure of benzene. arenes. 3. covalent. resonance. inductive effect. Classification & Nomenclature of organic compounds. bromination. Unit-IV Aromatic Compounds.

Organic Chemistry.. Finar. Unit-II : Sense Organs : Basic anatomy and physiology of the eye (vision). 60 B.P-Bromo acetanilide Iodoform Oxalic Acid BOOKS RECOMMENDED: 1. First Aid : Emergency treatment of shock. Cranial nerves and their functions. specialized functions of the brain. “ Naming organic compounds”. 2. B. Organic Chemistry. M..” Organic reactions Stereochemistry & Mechanism". formation and circulation of lymphs. lymph node 25    . fractures and resuscitation methods. ELBS/Longman. and spleen. burns. R. Jain. and skin (superficial receptors). nose (smell). Organic Chemistry. Medical termination of pregnancy. Demography and Family Planning. Bunglaw Road. Ltd. 3. New Delhi. ear (hearing).Kalsi. Neurohumoral transmission in the central nervous system. Mechanism of neurohumoral transmission the A. Vogel A.I. 8. 7. & Saunders. 6.S. I. 5.L.C. and Boyd R. Mann.. E. F. [07] [06] [05] Unit-III : Lymphatic System : Composition .N.W. Vol. electroencephalogram. Unit-IV : . 4. Practical Organic Chemistry. Organic Chemistry. poisoning. Textbook of Practical Organic Chemistry.T. Hendrikson. Morrison.N.. ELBS/Longman. Delhi. Sohan Lal Nagin Chand & Co. [06] [04] Autonomic Nervous System : Physiology and functions of the autonomic nervous system. I & II. reflex action. Prentice Hall of India Pvt. PHYSIOLOGY & PATHOPHYSIOLOGY-II Unit-I : Central Nervous System : Functions of different parts of brain and spinal cord.. taste buds. Godly. PHARM-123 ANATOMY. ELBS/ Longman. snake bites.G.K.

their causative agents. Single User Operating System and Multi-user Operating system. Samson Wright’s Applied Physiology. Parmar N. Ranade VG. 7. rabies. MAN. Pune. 2. helminthiasis. influenza. Churchill Livingstone. Niel. Computer Software.. Internetworking: Bridges.Interactive. Internal and External commands in MS-DOS. Computer Organization. [12] PHARM-124 COMPUTER FUNDAMENTALS AND PROGRAMMING Unit-1:Definition and Overview of Computer. Various window features. Repeaters and Routers. 8. Overview of Computer Networks. Ross & Wilson. tetanus. whooping cough. Health Education & Community Pharmacy CBS Publishers. poliomyelities.. Internet. C. Human Physiology. Oxford University Press. 26    . diphtheria. Medical Allied Agency. gonorrhoea. Computer code. Human Physiology. Delhi. Hall JE. and AIDS). “Atlas of Normal Histology” Lea & Febiger Philadelphia. Difore SH. Evolution of operating system. Shalya Subhash. Unit-2: Introduction: Operating system and function. LAN. Keele. 6. Input Devices Out put devices. filariasis.Unit-V Communicable Diseases : Brief outline. & Anagnodokos NP. Guyton AC. malaria. Types of software. modes of transmission and prevention (Chicken pox. Batch. Text Book of Practical Physiology. 4. Computer classification. syphillis. network topology. trachoma. 3. 5. Tortora GJ.A. measles. Anatomy & Physiology in Health & Illness. E and Joels N. Storage devices. leprosy. UNIX. Harper & Rave Publishers.S. CBS Publishers & Distributors. Principles of Anatomy & Physiology. BOOKS RECOMMENDED: 1. Chatterjee C. Text book of Medical Physiology. Intranet. tuberculosis. computer classification of Boolean algebra. Time sharing and Real Time System. New Delhi. WB Saunders Company.. 9. Compare MS-DOS vs. Pune Vidyarthi Griha Prakashan. WAN.C. Calcutta.

uses of Internet in Pharmaceutical Industry BOOKS RECOMMENDED: 1. Elements of Power point . Bar.Histogram. Unit 4: MS-Power point 2003-Job Profile. mail merge. PHI Publication. Important functions. PHARM-124P Computer Fundamentals and Programming Software Lab to be used for the following:1. Database language. Raja Raman. Database system concepts. Excel-2003. Preparation. “ Biostatistics & computer Applications”.K. N. ways of delivering Presentation.Tiwari. animation and multimedia effects. Internet Features (E-mail. main components of Access tables. G. Folders and files. Data models schema and instance . Practice and Presentation) ways of handeling presentations e.g. MS Access). 4. 5. MS Power point. MS-Office 2003 (MS Word.Unit. working on Query and use of database.3: Introduction to MS-OFFICE-2003.. Circular diagranm) Classification and Tabulation of data. 3. R. creating. short cut keys used in EXCEL. Editing. 2. saving slides show controls. Unit. BPB Publications.5: Computer applications in Pharmaceutical and clinical studies. 2. V. Browser etc. Adding formatting. MS Excel. Introduiction to MS-Access 2003. concept of Four P’s (Planning . Windows. Reports. Sinha. “Computers and Common Sense” Prentice Hall of India. working Retrieval. Editing. Hunt N and Shelley J. Sampling-Types of sampling 27    . 3. Computer Fundamentals. Computer Operating System Like DOS and Windows. formatting table handling. Method of collective data Diagramatic representation of data (Pie. Managing Windows. Queries. 3.K. Computer Programming in ‘C’.) PHARM-125 Pharmaceutical Biostatistics Unit-I 1. 4. Forms table handeling.” Computer fundamentals with Pharmacy Applications”. 2.Rao. 4. Working with Disk . word 2003 Document creation.N.

Mean deviation c. Sultan Chand and Co.Confidence (feucidial ) limit. NCERT Publication Vol. Binomial distribution. Khan. Practical and Clinical Application. Gupta S. N. Unit-II. Quartile deviation b.Merits and limitations of sampling Sampling errors and non sampling errors.Measure of central tendency for decrete and continuous data.one way and two way classification. Mean. 28    . 2. A textbook of Mathematics for XI-XII Students. Poisson distribution. ModeMeasure of dispersion a. New Delhi.” Biostatistics for Pharmacy”.1.Simple Probability Addition Probabilty Multiplication Probabilitty 2. Standard error of Mean (SEM) Unit-IIIa. Marcel Dekker. 4. Boltan’s Pharmaceutical Statistics.Fit of Poisson 4.test ( variance ratio) Analysis of variances. Higher Engineering Mathematics. I-IV. Srewness and Kurtosis b. Testy. Median c.S. Greval B. Normal distribution –Fit of Normal BOOKS RECOMMENDED 1..P.t-test z-test X2 –test F. a. Khanna Publication.Hypothesis. Types of means. 5.. 3. New Delhi. Theory of Probability. Statistical Methods.Y. b.Fit of Binomial 3. Correlation and regression analysis c. Khanum. Nonlin (ANOVA) Unit-V. Method of least square in straight line Unit-IV-Statistical Inferences.

equipment for dehumidification operations. Principles of centrifugation. Accident record. Chemical. Properties and applications of the materials of construction with special reference to stainless steel and glass. Psychrometric chart and measurement of humidity. Unit-II 3. Filtration and Centrifugation : Theory of filtration. filter media. 8. Solubility curves and calculation of yields. [06] 29    [10] [08] [08] . basic laws. Material of Construction : General study of composition. 2. Factors affecting filtration. basic situations of fluid flow. wet bulb and adiabatic saturation temperatures. Nucleation mechanisms. Material and heat balances around Swenson Walker Crystallizer. water for injection . cleaning and standardisation of cleaning. application of humidity measurement in pharmacy. and centrifugal sedimenters. Concept of boundary layer. Heating. resistance. shape. crystal growth. size. agitated batch. geometry. Viscosity. Swenson Walker. Unit-III 5. Study of various types of Crystallizer. habit. filter aids. valves. Reynold’s number. Ventilation & AC Systems: Basic concepts and definition. Water systems – Raw water. washing. edge filter. forms size and factors affecting them. corrosion. UNIT – IV 6. 4. Unit-V 7. Single vacuum. Industrial Hazards and Safety Precautions : Mechanical. fire and dust hazards. Unit Operations : Introduction. soft water. Principles and applications of refrigeration and air conditioning. Electrical. rotary filter. purified water. Caking of crystals and its prevention. Tanks.SEMESTER-III PHARM-231 PHARMACEUTICS-II (UNIT OPERATIONS-I) Unit-I 1. Industrial dermititis. Crystallization : Characteristics of crystals like-purity. Supersaturation theory and its limitations. industrial filters including filter press. industrial centrifugal filters. quality requirement and treatment of water. circulating magma and Krystal crystallizer. Fluid Flow : Types of flow. manometers and measurement of flow and pressure. flow meters.

Study of solubility curve of crystals. McCabe W. 6. Study of factors affecting rate of filtration a) Effect of different filter media b) Effect of viscosity of filtrate c) Effect of pressure d) Effect of thickness of cake e) Effect of filter aids. Gavhane. K. 4. b) Solid – liquid separation and stability of suspension. Pharmaceutical Engineering.C.L. and Smith J. Measurement of rate of flow of fluids and pressure by: a) Simple and differential manometers b) Venturimeter c) Orifice meter 2. and Banchero J.H. 3. & Chilton C. BOOKS RECOMMENDED 1. Unit Operation of Chemical Engineering Mc Graw Hill International Book Co. 5. 5. London. New Age Publishers. Introduction to Chemical Engineering Mc Graw Hill International Book Co.PHARM-231P PHARMACEUTICS-II (UNIT OPERATIONS-I) PRACTICAL 1. Sambhamurthy. Chemical Engineers Handbook. Study of characteristics of crystals 7. “Unit Opeation-I”. Nirali Prakashan... Perry R.T.H. 30    .A. Badger W. Study principle of centrifugation for a) Liquid –Liquid separation and stability of emulsions. 4. Determination of Reynold Number. 2. Mc Graw Kogakusha Ltd. Determination of dry bulb and wet bulb temperatures and use of Psychrometric charts. 3.L. London.

2. Pharmaceutical Ethics: Unit-II : An elaborate study of the following: (A) Pharmacy Act 1948 (B) Drugs and Cosmetics Act 1940 and Rules 1945 [14] Unit-III : (C) Medicinal & Toilet preparations (Excise duties Act 1955) (D) Narcotic Drugs & Psychotropic Substances Act 1985 & Rules.T.Vol. Unit-V : (F) A. 4. N.M. [07] [05] [08] [06] Unit-IV : A brief study of the following with special reference to the main provisions. Pharmaceutical Legislations – A brief review. Pharmaceutical Education – A brief review.I. Drugs & Pharmaceutical Industry – A brief review. 31    . (A) Poisons Act 1919 (B) Drugs and Magic remedies (Objectionable Advertisements) Act 1954. A Textbook of Forensic Pharmacy.E.-I. Jain.. Singh. 3. Sundari Mohan Avenue. 2. (E) States Shops & Establishments Act & Rules. Mittal. 4. (D) Prevention of Cruelty to Animals Act 1961. Vallabh Prakashan. Calcutta.PHARM-232 PHARMACEUTICAL JURISPRUDENCE & ETHICS Unit-1 : Introduction 1. (C) Medical termination of Pregnancy Act 1970 & Rules 1975. B. Harkishan “History of Pharmacy in India. Dr. 3. Textbook of Forensic Pharmacy. Act 1987 (G) Patents Act 1970 (H) Weight and Measures Act (I) Package and Commodity Act (J) U. BOOKS RECOMMENDED : 1. N.K. of India. Relevant Acts & Rules Published by the Govt. National Book Centre. (E) Drugs Price Control Order 1995.C. Delhi.S Food and Federal D&C Act Note : The teaching of all the above Acts should cover the latest amendments. II & III” Vallabh Prakashan.

Liliaceae. C. hydnocarpus oil. Plant taxonomy : Study of following families with special reference to medicinally important plants – Apocynacae. Compositae. 2. Acanthaceae. Systematic pharmacognostic study of following : a) Carbohydrates & derived products : Agar. [08] [02] [02] [01] [02] [04] [02] [04] 1. wool fat. Polyploidy. sterculia & tragacanth.PHARM-233 PHARMACOGNOSY – I Unit-I : Definition history. Rubiaceae. Novel medicinal agents from marine sources. Solanaceae. Processing & Storage of crude drugs : A. mineral and plant tissue cultures as source of drugs. microscopic. Morphological. Rutaceae. B. castor oil. Plant hormones and their applications. chemical and biological methods of evaluation including Quantitative microscopy. Unit-III : 4. Unit-IV : 5. physical. Classification of Drugs : Alphabetical.natural pest control agents. 32    . taxonomical. [07] [08] b) Lipids – Beeswax. shark liver oil. Labitae. Collection. Cultivation. pectin. Cocabutter. Umbelliferae. Type of Soils & fertilizers of common use. Marine pharmacognosy. Poly Houses/ Green Houses for cultivation. Factors influencing cultivation of medicinal plants. Papaveraceae. D. Mutation & hybridization with reference to medicinal plants. Codliver oil. Honey. Lard & Suet. marine. Linseed oil. Source of Drug : Biological. Leguminosae. [02] Unit-II : 3. acacia. E. chemical & pharmacological. Kokum butter. scope & development of Pharmacognosy. Quality Control of crude drugs : Adulteration of crude drugs and their detection by organoleptic. Isabgol. Rice-bran oil. Pest & Pest Management . Guar gum. starch. Unit-V : 6. WHO guidelines for standardisation of medicinal plants.

E. W. 5.C. Determination of vein-islet and vein termination number. Study of various types of phloem fibres. Cod-liver oil. Chemical Tests of Agar. Maize). Shark-liver oil and Linseed oil. Calcium oxalate Crystals & Phloem Fibres.) 8. Liquorice etc. Trease.PHARM-233P PHARMACOGNOSY . 12. Determination of stomatal index. Starch and Honey. SUGGESTED PRACTICALS 1. a) Chemical tests of Pectin. Microscopical measurements of starch grains (Wheat.I PRACTICAL 1. 11. & Evans. Potato). 6. b) Swelling factor of Isapaghula husk. Determination of stomatal number with the help of camera lucida along with the working of instrument. Study of Plants belonging to family Rutacae. 13. 5. 10. Physical characteristics of Caster oil.. Sterulia and Tragacanth. 2. Acacia. 33    . 15. Morphological characteristics of plant families mentioned in theory. 3. G. Microscopical Measurements of cell & cell contents Starch grains. 2. Determination of leaf Constants such as Stomatal index. Vein islet number. Various types of calcium-oxalate crystals. Study of Plants belonging to family Solanacae. c) Average weight of Ispaghula husk. 4. 7. Preparation of herbarium sheets. Senna. U. Microscopical measurements of starch grains (Rice. Study of Plants belonging to family Umbilliferae. “Pharmacognosy” Bailleire Tindall East bourne. BOOKS RECOMMENDED 1.K. Vein determination number and palisade ratio. 14. 9. Study of Plants belonging to family Liliacae 4. their study and microscopical measurements (Rhubarb. Determination of palisade ratio. Stomatal number. Identification of crude drugs belonging to carbohydrates & lipids. 3.

[08] Unit-III : Name reactions – Definition. fats and waxes. cycloaddition.Bristol. Scientechnica. London. J&A Churchill Limited. acids and proteins. Unit . Oppeneaur oxidation. benzimidazole. Ltd 4. “Marine Natural products”. identification. Diel’s alder reaction. phenothiazines.Unsaturated carbonyl compounds. thiophene. general methods of preparation and reactions of amino [08] 34    .A. Verley reduction. preparation. Benzoin condensation.. iii) Polysaccharides – Starch. imidazole. Analytical Microscopy. Schewer PJ.E. Wright.R. 7. [08] [08] Unit-V : Classification. Structure of Nucleic Acids. Mohammed Ali. pyridine. Text book of Pharmacognosy. T. Reformatsky. Wallis T. 8. identification of : a) Carbohydrates i) Monosaccharides – Glucose and fructose. reactions. Bechmann rearrangement. lactose and maltose. Chemistry & identification of oils. Knoevanegal reaction. Academic press. and Turner T D. Chemistry. “The Practical Evaluation of Phyto Pharmaceutical”. Mannich reaction.Acetoacetic ester and malonic ester. ii) Disaccharides – Sucrose. thiazole. Polynuclear hydrocarbons-Napthalene. anthracene and phenantherene. J. Brain K.2. PHARM-234 PHARMACEUTICAL CHEMISTRY .. Compounds containing active methylene group and their synthetic importance. London. indole. structure elucidation. Polymers and polymerisation. furan. “ Pharmacognosy & Phytochemistry”. properties and pharmaceutical importance of pyrrole.II : Heterocyclic Compound – Nomenclature. β.III (ORGANIC CHEMISTRY -II) Unit-I : ά. pyrazole. pyrimidine. Churchill. structure. reaction mechanism and synthetic application of Merwin –Pondorff.E. [08] Unit-IV: Classification. Wallis. 5. Michel.

stocking iii) Legal requirements iv) Maintenane of various registers v) Use of Computers Unit-II 3. London. sap value. Organic Chemistry. 6. Furniss B S. Finar.R. Delhi.. 2. Community Pharmacy Management i) Selection of site. 5. Shoban Lal Nagin Chand & Co. Jain.N. Determination of Iodine value . 3. Smith P W G and Tatehell A R. 4.parts of prescription. and Boyd. Organic Chemistry Vol. New Delhi.. Vogel’s Textbook of Practical Organic Chemistry.coding. Hannaford A J. legality & identification of medication related problems like 35    [06] . Synthesis of Organic Compounds involving two steps. Ester value of oils. Definition. scope of community pharmacy Roles and responsibilities of Community pharmacist.PHARM-234P PHARMACEUTICAL CHEMISTRY-III (ORGANIC CHEMISTRY-II) PRACTICAL 1. The ELBS/ Longman. BOOKS RECOMMENDED 1. ELBS/ Longman. Morrison. Private Limited. code of Ethics. Kalsi. 2. R. 2. Prentice Hall of India. and design ii) Staff. London. fats and waxes.. ELBS/Longman. Organic Chemistry. Prescriptions.K. T. I.L. Mann P G & Saunders B C.” Organic Reactions Stereochemistry & Mechanism”. M.C. Materials. Acid value. I & II. Identification of organic compounds and their mixture with derivatization. PHARM-235 PHARMACEUTICS – III (COMMUNITY PHARMACY) Unit-I 1. Practical Organic Chemistry. and Sharma S. 3. Space layout.

drug interactions incompatibility. role of pharmacist in improving the compliance. Health Education WHO Definition of health. Inventory control in community pharmacy. ABC. advisory labels 7. Factors affecting compliance. Role of Pharmacist in family planning. prevention of communicable diseases.Definition. nutrition. methods for screening Blood pressure/ blood sugar/ lung function And Cholesterol testing. 9. Pharmacoepidemiology & Pharmacoeconomics – Brief introduction 12. & layouts. 6. 11.content. care for children. Key communication skills. EOQ. importance. Strategies to overcome barriers Patient information leaflets. OTC Medication. Health screening services Definition. Pharmaceutical care Definition and Principles of Pharmaceutical care. VED. OTC medication list & Counseling Unit-V 10. Communication skills and Patient counselling Need for good communication. Rational drug therapy – Brief introduction [10] [06] [10] [08] 36    . various methods of Inventory Control. 4. and geriatric patients. Definition. Lead time. safety stock Unit-III 5. pregnant & breast feeding women. Patient compliance Definition. Unit-IV 8. and health promotion. design.

Delhi. 6. Introduction to Pharmaceutical Dosage Forms. Prescription handling and identification of drug interactions. 3. Carter S. 5. Remington Pharmaceutical Sciences. Design of community pharmacy to incorporate all pharmaceutical care services (as per schedule N). Project report on visit to the nearby Community for Counseling on the rational use of drugs and aspects of health care. Pennslyvannia. ELBS/ Churchil Livingstone. 4.J. Interpretation of various pathological report of blood and urine.. Study of OTC medications List & Available brands 7. Parmar N. Pharmaceutics – The Science of Dosage Form Design. Ansel H. CBS Publishers. incompatibilities..P. Her Majesty’s Stationary Office.. 37    .M. Delhi. Categorization and storage of Pharmaceutical products bases on legal requirements of labeling and storage. Mack Publishing Co. Cooper and Gunn’s Tutorial Pharmacy.J. CBS Publishers. B. Cooper and Gunn’s Dispensing for Pharmaceutical Students..S. 4.P. 6. Varghese & Co. 2. Community Pharmacy & Health Education. Health screening services and study of equipments for:Blood glucose determination (Glucometer) Blood pressure (BP apparatues) Lung function test (Peak flow meter) 5.PHARM-235P PHARMACEUTICS – III (COMMUNITY PHARMACY) PRACTICAL 1. Drugs & Cosmetics Act & Rules. Bombay. 8. CBS Publishers. I. K. 7. Govt of India Publication. 2.E.. 3.C. Aulton M. BOOKS RECOMMENDED : 1.. Cambridge. 9. Carter S.

Harper & Rave Publishers. hypertrophy. 10.PHARM -236 ANATOMY. Unit-V. Anatomy & Physiology in Health & Illness. Text book of Medical Physiology.base balance. Niel. Calcutta. Delhi. Human Physiology.S. intracellular accumulation & pathophysiology of Neoplasm. WB Saunders. their structure and functions. Zollinger. pathogenesis & morphology of cell injury. pathophysiology of renal feature. acid. 2. pancreatitis. New Delhi. Kumar V. Hepatitis. Various gastrointestinal secretions & their role. Guyton AC. Chaurasia B. Urinary tract infection.. Basic Pathology. Difore SH. BOOKS RECOMMENDED 1. 9.D. 8. Hall JE. Oxford University Press. Shalya Subhash. Parmar N. & dysplasia. Elsevier. 5. Ross & Wilson.A. 4. & Anagnodokos NP. Regional & Applied Part I. 7. [06] Unit-III – Urinary System – Anatomy & physiology of urinary system. Principles of Anatomy & Physiology. C. physiology of urine formation. Dipiro JL. New Delhi. Human Physiology. Cellular AS daptation. E and Joels N. aplasia. Crohns disease. 38    . II & III. migration of WBC’s mediaters of inflammation. Pharmacotherapy – A Pathophysiological Approach.Basic mechanisms involved in the process of inflammation and repair Alterations in vascular permeability and blood flow. Ulcerative colitis.Atropy. Samson Wright’s Applied Physiology. [08] Unit-IV-Cell injury & Adaption-Courses of cell injury. Cirrhosis of liver. CBS Publishers & Distributors. Human Anatomy. “Atlas of Normal Histology” Lea & Febiger Philadelphia. Medical Allied Agency. Health Education & Community Pharmacy CBS Publishers. 11. Chatterjee C. PHYSIOLOGY AND PATHOPHYSIOLOGY – III Unit I – Digestive system –Parts of digestive system. typhoid.Ellison syndrome. [08] Unit II –Pathology of disorders related to digestive system Peptic Ulcer. glomerulonephiritis. Brief outline of the process of repair. Keele.C. Amoebiasis. 3.. metaplasia. Tortora GJ. WB Saunders Company. CBS Publishers & Distributors. 6.. Churchill Livingstone. Robbins SL.

dimensionless equations. single effect and multiple evaporator. classification and type of dryers . evaporator. Azeotropic and extractive distillation . drying calculations. principles of rectification. Reactors and fundamentals of reactor design for chemical reactions. steady and unsteady states. Elements of computer aided manufacturing (CAM) . Elements of automatic process control and introduction to automatic process control systems. rate process. distillations . [08] Unit-V : Automated Process Control Systems : Process variables. mole fraction. simple steam and flash [08] PHARM-241P PHARMACEUTICS-IV (UNIT OPERATIONS-II) PRACTICAL 1. molecular units.SEMESTER IV PHARM-241 PHARMACEUTICS – IV (UNIT OPERATIONS – II) Unit-I : Stoichiometry : Unit proceses material and energy balances. film evaporators. [08] [08] Unit –IV : Drying : Moisture content and mechanism of drying . temperature. Mccabe thiele method for the calculations of number of theoretical plates. equilibrium state. Fluidized bed dryer. spray dryer and special drying methods. tie substance. Study of factors affecting rate of evaporation :a) Effect of surface area b) Effect of temperature 39    . . dimensionless groups. mole volume. pressure. dimensionless formulae. gas laws. Unit-II : Evaporation : Basic concepts of phase equilibria. Determination of overall heat transfer coefficient. dryers used in pharmaceutical industries – Tray dryer. different types of graphic representation. Phase Diagrams . factor affecting evaporation. rate of drying and time of [08] Unit -III : Distillation : Raoult’ s law . flow level and vacuum and their measurements. primary and secondary quantities. 2. volatility.

5. cultivation & isolation of bacteria & viruses.C. Gavhane. Unit Operation of Chemical Engineering Mc Graw Hill International Book Co. Classification of microbes and their taxonomy: Bacteria and viruses. Study of factors affecting rate of drying a) Surface area b) Temperature 4.. electron microscopy.L. Nirali Prakashan. New Age Publishers.H. Elementary knowledge of engineering drawing Alphabets/ letter writing Scales Orthographic projections – First and third angle projection methods Simple Isometric views BOOKS RECOMMENDED : 1.H. Identification of Microbes : Stains and types of staining techniques. London. and Banchero J. London.. free moisture content and bound moisture content.L. Mc Graw Kogakusha Ltd. McCabe W. 2. “Unit Operation-II”. 3. Perry R. 2. and Smith J. Sambhamurthi Pharmaceutical Engineering. Introduction to Chemical Engineering Mc Graw Hill International Book Co. Determination of rate of drying. K. Structure of bacterial cell. Unit-II : 4. Nutrition. 5. 4. 5. Experiments based on a) Steam distillation b) Extractive distillation c) Azeotropic distillation 6. & Chilton C. Chemical Engineers Handbook. [08] 40    [08] . Introduction to the scope of microbiology.A. PHARM-242 PHARMACEUTICAL MICROBIOLOGY Unit-I : 1.3.T. 3. Badger W.

10. manufacture of sterile products. Sterilization. validation of sterilization techniques. dynamics of disinfection. various staining methods.clean and aseptic area. control of hospital infections. Study of sterilization methods & equipments • • Dry heat Moist heat 2. fungus and yeast. Control of microbes by physical and chemical methods. Preservative efficacy Unit-V : 9. Sub-culturing of common bacteria. Microbial assays of antibiotics. testing the sterility of pharmaceutical products as per I. requirements. Isolation of bacteria. vitamin B12. evaluation of antiseptics and disinfectants. 4. 41    . A.P. yeast. Factory and hospital hygiene. sterilization techniques and their validation. validation of sterilization methods & equipments. fungi.control of microbial contamination during manufacture. different methods. 8. PHARM-242P PHARMACEUTICAL MICROBIOLOGY PRACTICAL Experiments devised to prepare various types of culture media. disinfectants And antiseptics and their evaluation. Identification and staining of bacteria. microbial assay of antibiotics and vitamins. factors influencing disinfectants. SUGGESTED PRACTICALS 1. sub-culturing of common aerobic and anaerobic bacteria. [08] Unit-IV : 7. Preparation of various types of culture media. various methods of isolation and identification of microbes. Sterility testing as per I.Unit-III : 6. nosocomial infection. 5. B.P. 3. Disinfection.

2. Turmeric. Valerian.L. 10. Disinfection and Sterilization. Microbiology and Infectious Diseases. Shellac. Gunasekaran P. Microbiology.. Asafoetida. 9. 5. Wheelis M. Stanier R. Capsicum. Coriander. Virella G. Lemon grass.M. Tissue Culture & Mushroom Cultivation. [05] Unit-II : Volatile oils : General methods of obtaining volatile oils from plants. PHARM-243 PHAMACOGNOSY – II Unit-I : Resins : Study of drugs containing Resins and Resin Combination like Podophyllum. Prescott L. Plant Pathology.R. New Age Publishers. Lab Mannual of Microbiology. Lemon peel. Caraway. J. Sykes. Cinnamon. Microbial assay of antibiotics as per IP. Balsam of peru. Pharmaceutical Microbiology. Dill. Orange peel. Jatamansi. 8. Tata Mc Graw Hill.A. McGraw Hill. Test for sterility of pharmaceutical products as per IP. Harley J.. 3. Benzoin. Textbook of Microbiology. & Klien D. Experiments in Microbiology. 6. Eisen Microbiology. Cumin. minimum inhibitory concentration. Clove. Spearmint. Gaultheria. 42    . 4.R. Chenopodium. Hugo and Russell. Ingraham. Ginger. & Painter P. 8. Ananthanarayan R & Paniker CKJ. Black Well Scientific Publication.Y. Cassia. Balsam of tolu. Cannabis. Black pepper. Nutmeg.. 6. Delhi. Evaluation of disinfectants and antiseptics 7. Eucalyptus. Macmillan Press Limited. Oxford. Citronella.L.P. Aneja K. Microbiology. General Microbiology. Musk. Study of volatile oils from Mentha. Palmarosa. BOOKS RECOMMENDED : 1. Dulbetco.• • • • • Simple staining Gram staining Acid fast staining Hanging drop preparation Phenol coefficient test. Fennel. 7. Vishwa Prakashan. Cardamom. William & Wilkins. Orient Longman. Davis. Pelczar & Reid.

Baheda. polyester and asbestos. Fullers earth. Steroids. Pharmaceutical aids :. Study of fibres and pharmaceutical aids. Morphology and microscopy of Coriander and Cinnamon. [14] [03] [02] [03] [03] Unit-IV : Fibres : Study of fibres used in pharmacy such as cotton. classification and properties with Qualitative chemical tests of the followings – Alkaloids. Bentonite. 4. Diatomite. 2. Geranium oil & Eucalyptus oil. Arjuna & Ashoka). Study of Cotton. 3. Role of aromatic plants in national economy. Morphology and microscopy of Dill and Caraway. 43    . Euncalyptus. Morphology and microscopy of Cardamom and Fennel. Ginger. cyanogenetic glycosides. SUGGESTED PRACTICALS 1. 6. Gall and Myrobalans (Harde. glasswool. and Kaolin. nylon. 5. To study the morphology and chemical tests of Talc. flavonoids and Leucoanthocyanidine. silk. Nutmeg and chenopodium. Morphology of Turmeric. Gelatin and Natural colors. Unit-V : Tannins : Study of tannins & tannin containing drugs like Gambier (Pale Catechu). Saponins.Sandalwood. Cannabis.Study of Pharmaceutical aids like Talc. Utilization of aromatic plants & desired products will special reference to Sandalwood oil. PHARM-243P PHARMACOGNOSY – II PRACTICAL 1. Diatomite. 7. Kaolin. 3. Vetiver oil. Lemongrass. 2. Microscopic study of seven selected drugs and their powders mentioned under the category of volatile oils in theory with their chemical tests. wool. General chemical test for Alkaloids. Glycosides. Cardenolides and bufadienolides. Silk and Wool along with their chemical Tests. Morphology of Mentha. 4. Flavonoids & Tannins. 8. [10] Unit-III : Phytochemical Screening : An introduction to active constituents of drugs : Their isolation. Mentha oil. Morphology and microscopy of Clove and to study its transverse section. Identification of crude drugs mentioned in theory. Black Catechu. Lemon grass oil.

K. et al “Pharmacognosy” Lea & febiger.K. reference and indicator electrodes. London.. “Pharmacognosy” Balliere Tindall East Bourne U.” Pharmacognosy & Phytochemistry”. Tests for identification of steroids.. PROJECT WORK : Utilization of Aromatic plants. 12. Dielectric cell. . Karl.E. To perform the chemical tests of Balsam (Tolu and Peru) and Asafoetida. Preparation of reagents for the chemical tests of Alkaloids and to perform the chemical tests on any Alkaloid containing drug. 14. 4. salt bridge. & Evans W. PHARM-244 PHARMACEUTICAL ANALYSIS. Test for identification of Tannins. Tyler V. 15. Trease G. Jammu.II Unit-I : Theoretical considerations and application in drug analysis and quality control by the following analytical techniques (assays included in the Indian Pharmacopia 1996) (A) Non-aqueous titrations (B) Complexometric titration. Wallis. 3.E. & Kapur BM. Chapman & Hall International Edition. 6. Kokate C. measuring the relative voltage of cell. 5. Alcohol estimation in galenicals Potentiometry (B)Radioassays. 10. et al “Pharmacognosy” Nirali Prakashan. T. Morphology and microscopy of Bentonite.9. 2. 7.E. Test for indentification of Glycosides (Saponin and Anthraquinone). Harborne J B.K. “Text Book of Pharmacognosy” J&A Churchill Ltd. London. electrode potential. Kjeldahl method of Nitrogen estimation. RRL. “Cultivation & utilization of Medicinal plant. BOOKS RECOMMENDED : 1. Phytochemical method. 11. Mohammed Ali. Tests for identification of flavonoids.Fischer titration. 44    [08] [08] Unit-III : Demistrometry – Introduction. Gelatin and natural colours (Soffron). Unit-II : (A) Miscellaneous methods of analysis : Diazotization titrations. ((Monograph). Nernst equation. Atal C. standard potential.C. Philadelphia. Pune. 13.

2. Kjeldahil. Non-aqueous Titrations : Preparation and standardization of perchloric acid and sodium/potassium methoxide solutions. “Vogel’s Text Book of Quantitative chemical” Pearson Education Asia. Vol. Karlfisher.K. 3. Exercise based on acid base titration in aqueous and non-aquous media. 6. Wiley Intescience. Barnes. 2. Conductometry : General Principles. instrumentation and pharmaceutical applications. I and II. University Press. B.layer chromatography. Mendham J. [08] [08] Unit-V : Principle.II PRACTICAL 1. Pharmacopoeia of India. Delhi. Estimation of some pharmacopoeial products. Thomas M. A Textbook of Pharmaceutical Analysis. published by The Controller of Publications.B. determination of acid base dissociation constants and plotting of titration curves using pH meter.General principles.Vidya Sagar. 45    . Exercises based on paper. column and thin. Cambridge. Beckett.D. J. 3. instrumentation and applications. 5. Complexometric Titrations : Preparation and standardization of EDTA solution some exercise related to pharmacopoeial assays by Complexometric titrations. TLC [08] Unit-IV: Polarography and Amperlometry. 6. G. oxidation reduction titrations using potentiometric technique. Miscellaneous Determinations : Exercise involving Diazotization. Chromatography. Practical Phamaceutical Chemistry.A. New York. 4. Instrumentation and Applications PHARM-244P PHARMACEUTICAL ANALYSIS . 4. J. Her Majesty’s Stationary Office.Connors KA.J. British Pharmacopoeia. The Athlone Press of the University of London. 5.Exercises involving conductometric titrations. Paper column. Denny RC. instrumentation and applications. BOOKS RECOMMENDED : 1. A H and Stenlake.” Instrumental Methods of drug Analysis”. Potentiometry : General principles.

spermatogenesis. Guyton AC. hypersensitivity..Diabetes mellitus. Keele. allergic conditions. thyroid. WB Saunders Company. Hall JE. parathyroid. 4. AIDS. 6. oogenesis. 10. cardiac arrhythmias. Pathophysiology of hypertension. Kumar V. Emphysema. control of harmone secretion. Chaurasia B. 11. Mechanism of respiration. Tuberculosis. Dipiro JL.g. BOOKS RECOMMENDED 1.C.S. 7. gout.D. Parkinson & Alzeimer’s diseases pathophysiology of cataract. Regional & Applied Part I.A. 2. 3. epilepsy. Ischaemic heart disease. E and Joels N. pancreas.. New Delhi. CHF. Delhi. Human Physiology. 5. glaucoma etc. spasticity. [08] Unit IV – Endocrine System – Anatomy & Physiology of pituitary.PHARM-245 ANATOMY PHYSIOLOGY AND PATHOPHYSIOLOGY –IV Unit-I – Respiratory System – Anatomy & function of respiratory structures. [06] . Basic Pathology. Churchill Livingstone. [08] Unit-II – Cardiovascular System – Functional Anatomy of heart. CBS Publishers & Distributors. ECG (Electro cardiogram). II & III. New Delhi. Robbins SL. pathophysiology of Asthma. & Anagnodokos NP. myasthenia gravis. adrenal.Pathophysiology of Joints disorder – Arthritis. 8. Samson Wright’s Applied Physiology. Parmar N. Arteriosclerosis. of sexually transmitted diseases. regulation of respiration. Pneumonia. Calcutta. Medical Allied Agency. Text book of Medical Physiology. C. Human Anatomy. Ross & Wilson. 46    [08] Unit-V. 9. Health Education & Community Pharmacy CBS Publishers. Angina. Pathophsiology of anaemia. [10] Unit-III – Reproductive System. Principles of Anatomy & Physiology. myocardial infarction. Chatterjee C. tetany. Niel. Shalya Subhash. Anatomy & Physiology in Health & Illness.. Human Physiology. Bronchits. WB Saunders. Difore SH. Harper & Rave Publishers.Male & Female reproductive system. Oxford University Press. Pharmacotherapy – A Pathophysiological Approach. fatigue. conducting system of heart. Tortora GJ. Elsevier. cardiac cycle. pathophysiology of hypo & hyper secretion of endocrine glands & their disorders e. pathophysiology pregnancy. CBS Publishers & Distributors. Menstruation. physhosis.. “Atlas of Normal Histology” Lea & Febiger Philadelphia.

Biosynthesis of amino acids. Genetic Code and Protein synthesis. [08] [08] [08] [08] Unit-V 9. mechanism of oxidative phosphorylation. components of protein synthesis. 8. Lipid metabolism : Oxidation of fatty acid & energetics. Role of sugar nucleotides in biosynthesis and pentose phosphate pathway. Unit-II 3. Carbohydrate metabolism : Glycolysis. Gluconeogenesis and Glycogenolysis. Metals as co-enzymes and their significance. Enzymes :Nomenclature. regulation of lipid metabolism. essential fatty acids. Unit-III 5. Biosynthesis of saturated and unsaturated fatty acids. mechanism of inhibition of enzymes and isoenzymes in chemical diagnosis. 47    . DNA replication.SEMESTER -V PHARM-351 PHARMACEUTICAL CHEMISTRY – IV (BIOCHEMISTRY) Unit-I : 1. 6. reactions and energetics of the cycle. Metabolism of galactose and galactosemia. 2. Carcinogensis & DNA repair mechanism.. Unit-IV 7.. enzymes-kinetics and mechanism of action. its role in energy capture & control. formation of deoxyribonucleotides. The citric acid cycle. significance. Biosynthesis of RNA. Co-enzymes:Vitamins as co-enzymes and their significance. Energetics of oxidative phosphorylation. inhibition of protein synthesis. biosynthesis of purine and pyrimidine. Biological Oxidation : The respiratory chain. 4. catabolism of amino acids and conversion of amino acids to specialized products. Biosynthesis of ketone bodies and their utilization.

Bioinformatics. New Delhi. 4. Principles of Biochemistry”. Effects of temperature on the activity of alpha amylase.. L. 3. BOOKS RECOMMENDED : 1. Determination of glucose by means of the enzyme glucose oxidase. Plummer. Quantitative estimation of amino acids.. Regulation of gene expression. W. Outline of Biochemistry. Philadephia. (Prokaryote and Eukaryote) PHARM.. San Francisco..K. Singh S. Nelson. phosphate and carbonate) and measurement of pH. ‘ Lehninger . New Delhi.. New Age International Publishers Delhi. Estimation of cholesterol in Blood. 10. Estimation of Urea in blood. 9. & Mazur A. 7. Saunders Co. Estimation of ketone bodies in blood. Preparation of standard buffers (citrate. Titration curve for amino acids. John Willery & sons. Practical Manual to Biochemistry. Macmillan Worth Publishers. Laboratory Manual in Biochemistry. 8.. 10. Stryer L. Wiley Eastern Limited. 6. Lehninger Principles of Biochemistry. Mc Graw Hill. 13. Estimation of Glucose in blood & urine. Nelson DL & Cox MM. An Introduction to Practical Biochemistry.E. & Stumph P. 4. 2.A Premier.. CBS Publisher. 3. PHARM-352 PHARMACEUTICS – V 48    . David J. 11. Harrow B.10. Qualitative analysis of inorganic as well as organic constituents of Urine. Separation of lipids by TLC. 5. New York. Separation of amino acids by chromatography..David. 8. Enzymatic hydrolysis of glycogen by α & β amylase. 6. Narayanan P.B. “Harpers Review of Biochemistry” Lange Medical Publication. Jayaraman J. Freeman & Company. WH. 5. 12. 9. Text book of Biochemistry. Biochemistry.P. Conn E. 7.351P PHARMACEUTICAL CHEMISTRY-IV (BIOCHEMISTRY) PRACTICAL [08] 1. 2.

Shampoos. suspending agents. deodorant. evaluation and packaging. [08] Unit-II : Liquid Dosage Forms : Introduction. suspensions and emulsions. preservatives. density. mechanisms of drug penetration. Nail lacquer. [08] [08] PHARM-352P PHARMACEUTICS-V 49    . antiperspirants. [08] Unit-IV : Suppositories : Ideal requirements.(PHARMACEUTICAL TECHNOLOGY -I) Unit-I : Preformulation studies : Study of physical properties of drug like physical form. [08] Unit-III : Semisolid Dosage Forms : Definitions.vanishing cream. vehicles. Conditioner. Solubility. particle size. flavours and others. Lipstick. semisolid bases and their selection. solubilizers. colors. Hair structure. stabilizers. protective cream. packaging and evaluation. bases. Manufacturing packaging & evaluation of clear liquids. all purpose cream. factors fluencing penetration. Shaving and after shaving products. dielectric constant. manufacturing and packaging methods. General formulation of semisolids. cleansing cream. formulation of cold cream. dissolution and organoleptic properties and their effect on formulation. Propellants.face powder. emulsifying agents. types. Pharmaceutical Aerosols: Definition. shape. general formulation. pharmaceutical applications. Unit-V : Cosmetology and cosmetic Preparations : Structure of skin. manufacturing procedure. types of additives used in formulations. clear gels & manufacturing procedure. Dentifrice & Mouthwash. stability and bioavailability. wetting.

(PHARMACEUTICAL TECHNOLOGY-I)

PRACTICAL 1. Preparation of cold cream, vanishing cream, cleansing lotion and creams. Moisturising creams, Skin tonics, Hair creams, Hair Conditioners, Shampoos, Shaving creams and sticks. Tooth powder, Tooth pastes, After shave lotion and other cosmetic preparations. 2. Preparation, evaluation and packing of liquid orals like solutions, suspensions and emulsions, ointments, suppositories, eye drops, eye ointments etc. SUGGESTED PRACTICALS 1. Preparation, evaluation, and packing of (10 preparations =5 labs) I- Liquid Orals a) Solutions : Strong Sodium salicylate oral solution BP Chloral hydrate oral solution BP b) Suspensions : Magnesium sulphate oral suspension BP Milk of magnesia IP Aluminium hydroxide gel IP c) Emulsions : Liquid paraffin oral emulsion BP II – Semi-Solids d) Ointments Salicylic acid ointment BP Whitfield ointment BP Compound benzoic acid ointment III - Suppositories e) Suppositories : Glycerin suppositories BP Lactic acid suppositories BP 3. Preparation of cosmetic preparations (30 preparation = 10 labs) 1) Cold cream 2) Vanishing cream 3) Cleansing cream 4) All purpose cream 5) Protective cream 6) Foundation lotion 7) Sunscreen lotion 16) Cream shampoo 17) Clear liquid shampoo 18) Shaving cream 19) Brushless shaving cream 20) After shave lotion 21) Hair fixer gel 22) Tooth powder
50   

8) Face powder 9) Body powder 10) Hand cream 11) Face pack 12) Deodorant 13) Antiperspirant 14) Shampoo- powder 15) Oily shampoo

23) Tooth paste 24) Mouth wash 25) Hair conditioner 26) Anti dandruff shampoo 27) Depilatory cream 28) Bleach cream 29) Hair setting lotion 30) Tooth gel

BOOKS RECOMMENDED 1. Remington’s Pharmaceutical Sciences, Vol. I & Vol. – II, Mack Publishing Co., U.S.A. 2. J.W. Cooper, & G. Gunn, Tutorial Pharmacy, Petman Books Ltd., London. 3. Lachman L., Lieberman H.A, Kanig J.L, Theory and Practice of Industrial Pharmacy, Lea & Febiger, Philadelphia, U.S.A. 4. H.C. Ansel, Introduction to Pharmaceutical Dosage Forms, Lea & Febiger, Philadelphia, U.S.A. 5 R.L. Juliano, Drug Delivery Systems, Oxford University Press, Oxford. 6. Harrys Cosmetology 7. Balsam and Sagarin, Cosmetics: Science and Technology. 8. Thomssen E.G. Modern Cosmetics, Universal Publishing Corporation. 9. Mittal B.M. & Saha R.N.-a handbook of cosmetics, Vallabh Prakashan. 10. Harry G.Brittain,” Polymorphin in Pharmaceuticals Solids”.

PHARM-353 PHARMACOLOGY – I Unit-I : General Pharmacology – Introduction to pharmacology, routes of drug administration, combined effect of drugs,factors modifying drug action. Bioassay of drugs & Biological standardization. Discovery & development of new drugs. [07]

Unit-II : Basic Concepts of Pharmacokinetics- Absorption, Distribution, Metabolism, Excretion Pharmacodynamics ,Principles of drug action ,Mechanism of drug action , Receptors, Dose
51   

Response curve,Therapeutics index -LD 50 & ED50,. Adverse drug reactions & treatment of poisoning. drug interactions, Unit-III : Pharmacology of ANS Drug acting on autonomic nervous system I-Cholinergic systemParasympathomimetic (Cholinergic ) drugs. Parasympatholytic (anti Cholinergic) drugs. Drug acting on autonomic ganglia (Stimulants and blocking agents) II-Adrenergic system Sympathomimetic (Adrenergic) drugs Sympatholytic (Anti-adrenergic) drugs [08] [07]

Unit-IV : Pharmacology of CNS General Anaesthetics, Alcohols & disulfiram, Sedative hypnotics, Psychopharmacological agents-anti anxiety agents ,antipsychotics, antidepressants. Antiepileptic drugs, Antiparkinsonism drugs, Analgesics & antagonists. [12]

Unit-V : Drugs acting on PNS Local anesthetics Skeletal muscle Relaxants Peripherally and Centrally acting muscle Relaxants [06]

PHARM-353P PHARMACOLOGY- I PRACTICAL 1. Use of computer simulated CDs or Video cassetes for pharmacology practical where possible. 2. Preparation of different solutions for experiments. Drug dilutions, use of molar and w/v solutions in experimental pharmacology. Common laboratory animals and anesthetics used in animal studies. Commonly used instruments in experimental pharmacology. Some common and standard techniques. 3. Study of different routes of administration of drugs in mice/rats. To study the effect of hepatic microsomal enzyme inhibitors and induction on the pentobarbitone sleeping time in mice, using software alternative to use of animals.
52   

Fundamentals of Experimental Pharmacology. Bombay. Physostigmine. K. New Delhi. Editors: J. Pharmacology Churchill Livingstone. Jay Pee Publishers. 8. Grover J. Molinos. Methohexital. geometric and bioisosterism) of drug molecules and biological action. MN.B. Ketamine. Essentials of Pharmacology. New Delhi. Saundar. Delhi.G. Hand Book of Experimental Pharmacology. structure activity relationship of the following classes of drugs (Synthetic procedures of individually mentioned drugs only) Unit-II : Drugs acting at Synaptic and neuro-effector junction sites: Cholinergic. R. Rang MP. Goodman & Gilman. Hardman.K. Essentials of Medical Pharmacology. Ruddon and A. Pharmacology & Pharmacotheropeutics. Calcutta.K: Text Book of Pharmacology. 53    . Adrenergic Drugs-Ephedrine. Adrenaline.K. Academia Publishers. Singh. uses. Delhi. Ghosh.. Tripathi.[08] [08] Unit-III:Drugs acting on the Central Nervous Systerm : General Anaesthetics-Thiopental. Prentice Hall. Katzung. P. 6.G. The Pharmacological basis of Therapeutics. L. Limbird. 11. Methacholine. Dale MM. 4. Pilocarpine. Pergamon press.. B. 9. Barar F.. International. Experiments in Pharmacy & Pharmacology.K. [08] Mode of action. Atropine. Riter JM. Popular Prakashan Pvt. Basic & Clinic Pharmacology. New Delhi. CBS Publishers. concept of prodrug. Gil. 2..D. BOOKS RECOMMENDED : 1. Satoskar & Bhandarkar. 3.. Salbutamol. U.S.W. 5. ISBN 1-874758-02-6 PHARM-354 PHARMACEUTICAL CHEMISTRY -V (MEDICINAL CHEMISTRY –I) Unit-I : Basic Principles of Medicinal Chemistry: Physicochemical aspects (Optical.. Ltd. Vallabh Prakashan. Sheffield Biocsience Programs. 10. Drug-receptor interaction including transduction mechanism. Interpoint. Amphetamine. Scientific Book Agency.G.E. Anticholinergic & Anticholinesterases-Neostigmine. 7. Kulkarni S.

Local Anaesthetics-Lignocaine, Benzocaine. Sedatives and Hypnotics-Phenobarbitone, Alprazolam. Opioid Analgesics-Pethidine, Methadone, Pentazocine. Unit-IV: Antitussives-Cramiphen, Dextromethorphen. Anticonvulsants-Phenytoin, Carbamazepine, Ethosuximide, Valproic Acid. Antiparkinsonism drugs-Carbidopa, Levodopa. CNS Stimulants-Caffeine, Nikethamide. Unit-V :Psychopharmcological Agents : Antianxiety drugs- Diazepam, chlordiaze Poxide. Antidepressants – Imipramine, Amitriptyline Fluoxetine. Antispasmodic and Antiulcer drugs-Dicyclomine, Ranitidine, Omeprazole. Skeletal muscle Relaxants– Gallamine Mephenesin, Antipsychotic- Chlorpromazine, Haloperidol. [08] [08]

PHARM -354P PHARMACEUTICAL CHEMISTRY-V (MEDICINAL CHEMISTRY-I) PRACTICAL 1. Synthesis of selected drugs from the course content involving two or more steps. 2. Establishing the pharmacopoeial standards of the drugs synthesized. SUGGESTED PRACTICALS 1. Synthesis of Methyl salicylate. 2. To establish pharmacopoeial standards of Methyl salicylate. 3. Synthesis of Paracetamol. 4. To establish pharmacopoeial standards of Paracetamol. 5. To synthesize Benzocaine. 6. To establish pharmacopoeial standards of Benzocaine. 7. Synthesis of Phenytoin. 8. To establish pharmacopoeial standards of Phenytoin.
54   

9. Synthesis of Barbituric acid desivatives. 10.To establish pharmacopoeial standards.

BOOKS RECOMMENDED : 1. Mann P G & Saunders B C, Practical Organic Chemistry, ELBS/Longman, London. 2. Furniss B A, Hannaford A J, Smith P W G and Tatehell A R, Vogel’s Textbook of Practical Organic Chemistry, The ELBS/ Longman, London. 3. Pharmacopoeia of India, Minsitry of Health, Govt. of India. 4. Wolff ME. Ed. Burger’s Medicinal Chemistry, John Wiley & Sons, New York. 5. Degado J.N. and Remers W A R, 10th eds., Wilson and Giswold’s Text book of Organic Medicinal and Pharmaceutical Chemistry, Lippincott, William & Wilkins. 6. Foye W C. Principles of Medicinal Chemistry, Lea & Febiger, Philadelphia. 7. Singh Harkrishan and Kapoor, V.K., Organic Pharmaceutical Chemistry, Vallabh Prakashan, Delhi. 8. Nogrady T, Medicinal Chemistry – A Biochemical Approach, Oxford University Press, New York, Oxford. 9. Finar I L. Organic Chemistry, Vol I & II, ELBS/ Longman, London. 10. Lednicer, D. The Organic Chemistry of Drug Synthesis Vol. I-V, John Wiley & Sons Inc. New York.

PHARM-355 PHARMACEUTICS – VI (PHYSICAL PHARMACY) Unit-I :(A) Matter, properties of Matter : States of matter, change in the state of matter, latent heat and vapor pressure, sublimation critical point, Eutectic mixtures, gases, relative humidity, liquid complexes, liquid crystals, glassy state, solids-crystalline, amorphous and polymorphism. [02] (B) Kinetics and Drug Stability : General considerations & concepts, Degradative pathways, half life determination, Influence of temperature, light, solvent, catalytic species and other factors, Accelerated stability study, expiration dating. ICH guidelines for stability. [05]
55   

(C) Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting is tonicity. [02] Unit-II: Micromeritics and Powder rheology: Particle size and distribution, average particle size, number and weight distribution, particle number, methods for determining particle volume, optical microscopy, sieving, sedimentation, measurement, particle shape, specific surface, methods for determining surface area, permeability, adsorption, derived properties of powders, porosity, packing arrangement, densities, bulkiness & flow properties. tension, surface free energy, measurement of surface and interfacial tension, spreading coefficient, adsorption at liquid interfaces, complex films,electrical properties of interface. Surface active agents, HLB classification, [08] solubilization, detergency, adsorption at solid interfaces, solid- gas and solid-liquid interfaces, Unit-IV : Viscosity and rheology : Newtonian systems, Law of flow, kinematic viscosity, effect of temperature, non-Newtonian systems, pseudoplastic, dilatant, plastic, thixotrophy, thixotropy in formulation, determination of viscosity, capillary, falling ball, rotational viscometers. Complexation : Classification of complexes, methods of preparation and analysis,applications. [08] Unit-V : Dispersion Systems : Colloidal Dispersions : Definition, types, properties of colloids, protective colloids, application of colloids in pharmacy; Suspensions and Emulsions; Interfacial properties of suspended particles, settling in suspensions, theory of sedimentation, effect of Brownian movement, sedimentation of flocculated particles, sedimentation parameters, wetting of particles, controlled flocculation, flocculation in structured vehicles, rheological considerations;Emulsions-types, theories, physical stability. [08] [07] Unit-III : Surface and Interfacial Phenomenon : Liquid interface, surface and interfacial

PHARM-355P PHARMACEUTICS – VI (PHYSICAL PHARMACY)
56   

6. Philadelphia. compressibility. Oxford University Press. 11. Experiments involving tonicity adjustments. 57    . Study of rheological properties of various types of systems using different Viscometers. Determination of derived properties of powders like density. Particle size distribution and surface area using various methods of particle size analysis. porosity.PRACTICAL 1. Studies of different types of colloids and their properties. Bustamante P. angle of repose etc. shelf-life determination and expiration dating of pharmaceuticals. 4. Preparation of various types of suspensions and determination of their sedimentation parameters. HLB value and critical micellar concentration of surfactants. BOOKS RECOMMENDED : 1. Lea & Febiger. To study the influence of various factors on the rate of reaction. & Chun A. 9.C. London.” Essentials of Physical Pharmacy”. 7. 12. 13. rate constant and order of reaction. Shotten E & Ridgaway K. Preparation and stability studies of emulsions.Physical Pharmacy. Physical Pharmaceutics. Determination of half-life. 5.Derle . Studies of different types of complexes and determination of their stability constants. 8. 3.H. 2. 3 D. 10.V. Accelerated stability testing. Determination of surface/ interfacial tension. Martin A. 2. Determination of particle size. Preparation of pharmaceutical buffers and determination of buffer capacity.

Spironolactone. Structure based drug design.Methotaxate 6. [08] Unit. [08] Unit-V: Diuretics – Acetazolamide. Introduction to Analogues based drug design. Ibuprofen.Isosorbide mononitrate Antihypertensive drugs-Captopril.SEMESTER –VI PHARM –361 PHARMACEUTICAL CHEMISTRY-VI (MEDICINAL CHEMISTRY . Nifedipine. Unit-IV : Analgesics and Antipyretics – Aspirin. Nalidixic acid. Carmustine Antimetabolites. methyldopa. Sulphadiazine. Diclofenac.Heparin. Anticoagulants. Sulphacetamide. Mefeanamic Acid.II Cordiac glycosides & drug used for CHF-Digitoxin Antiarrhythmic drugs-Propranolol.Paracetamol.Lovastatin. Fluorouracil .Chlorambucid. [08] 58    . Antibacterials – Sulphamethoxazole. mercaptopurine 5. Introduction to QSAR & Computer aided drug design. Clofibrate [08] Unit-III Anti cancer drugs Alxylating Agents. worfarin Antihyperlipedmics. Procainamide Antianginal drugs.II) Unit-I-Drug Design Basic concept of drug design. Furosemide. Chlorthiazide.

Wilson And Gisworld’s Text book of Organic Medicinal and Pharmaceutical Chemistry. Practical Organic Chemistry. 11. Pandi Veerapandian. 59    .K. Organic Chemistry. Capsules: Advantages and disadvantages of capsule dosage form. Ed. Establishing the pharmacopoeial standards of the drugs synthesized. New York. PHARM-362 PHARMACEUTICS-VII (PHARMACEUTICAL TECHNOLOGY .” Structure-Based Drug Design”. Ministry of Health. 5. Govt. Delagado J N and Remers W A R. of India. Furniss B S. Spectral analysis of the drugs synthesized. New York. BOOKS RECOMMENDED : 1. Wolff ME. size of capsules. 9. T. Lippincott Co. Hannaford A J. Oxford University Press. Lea & Febiger. Synthesis of selected drugs from the course content involving two or more steps. Finar I L. stability testing and storage of capsule dosage forms. Delhi. The ELBS/ Longman. Pharmacopoeia of India. 4.. methods of capsule filling. soft gelatin capsule shell and capsule content. quality control. Vol I & II. ELBS/ Longman. Oxford. 7. Nogrady. Philadelphia. material for production of hard gelatin capsule.II) Unit-I : 1. V. Mann P G & Saunders B C. 8. London.Thomas J. Vallabh Prakashan. Philadelphia. J.. importane of base adsorption and minim/gm factors in soft capsule. Smith P W G and Tathell A R. London. Foye W C. Singh Harkishan and Kapoor. Organic Pharmaceutical Chemistry.. Principles of Medicinal Chemistry. Medicinal Chemistry – A Biochemical Approach. 6. 2. 2.PHARM-361P PHARMACEUTICAL CHEMISTRY -VI (MEDICINAL CHEMISTRY-II) PRACTICAL 1. Vogel’s Textbook of Practical Organic Chemistry. 3. 10. Eds. London. Burger’s Medicinal Chemistry. John Wiley & Sons..Perun. ELBS/ Longman.” Computer –aided Drug Design methods applications’. 3.

spray congealing. surgical gauzes etc. evaluation of micro capsules.legal and other official requirements for containers. (B) Coating of Tablets : Types of coating. In-vitro methods of 60    . evaluation of tablets. evaluation of coated tablet. specifications and methods of evaluation. package testing. microencapsulation by phase co-acervation separation. preparation of solution and suspensions. complex. [08] [07] [08] [09] Unit-III : (A) Approaches to Sustained and controlled release dosage forms. primary wound dressing. routes of administration. water for injection. Formulation details. coating pan and other techniques. equipment for large scale manufacture and evaluation of parenteral products. containers and closures and their selection. film forming materials. lyophilization & preparation of sterile powders. ligatures and catguts. importance of microencapsulation in pharmacy. absorbable and non absorbable sutures. equipments for coating process. emulsion. granulation technology on large-scale by various techniques. stability aspects of packaging equipments. physics of tablets making. Stability kinetics and quality assurance. Micro-encapsulation : Types of microcapsule. absorbents. (B) Formulation and evaluation of Opthalmic. Unit-V : Surgical Products : Definition. surgical cotton. spray drying. bandages. evaluation. Nasal and Ear products. adhesive type. vial. protective cellulosic hemostasis. . air suspension technique. official dressings. formulation of coating solution. Prefilling treatment. different types of tablet compression machinery and the equipments employed. polymerisation. pyrogenicity. Packaging of Pharmaceutical Products : Packaging component types.2. formulation. nonaqueous vehicles. washing of containers and closures. factors influencing choice of containers. multi orifice. Unit-IV : Parenteral Products : Preformulation factors. infusion fluids. filling and sealing of ampoules. [8] Unit-II : Tablets : (A) Formulation of different types of tablets.

61    . 2. Vol-I. H.Evaluation of packages – containers & closures. Experiments to illustrate preparation. a) Capsules : Chloramphenicol capsules IP b) Microcapsules : Coacervation Phase separation (Temperature change) c) Tablets : Uncoated – Paracetamol tablets IP d) Tablets : Film coated – Ibuprofen tablets IPs e) Tablets : Enteric coated – Aspirin tablets f) Parenteral : Disodium EDTA injection IP (vials) g) Parenteral : Dextrose – NaCl IV infusion IP (Infusion boilers) h) Parentrals : Water for infection IP (Ampoule) i) Eye drops : Zinc sulphate IP j) Eye ointment : Sulphacetamide Sodium IP II . Introduction to Pharmaceutical Dosage Forms.C. I & III. R. Avis. BOOKS RECOMMENDED 1. 2. U.Formulation and evaluation of sustained release dosage forms – Aspirin Extended release (Matrix embedding method.S. Lea & Febiger.E. Pharmaceutical Dosage Forms : Parenteral Medication. stabilization & physical evaluation of pharmaceutical products like powders.A. parenterals & microcapsules. 3. Evaluation of Materials used in pharmaceutical packaging. capsules. Remington: The Science and Practice of Pharmacy Pharmaceutical Sciences Vol. Packing of the following dosage forms. tablets.PHARM-362P PHARMACEUTICS-VII (PHARMACEUTICAL TECHNOLOGY .A. SUGGESTED PRACTICALS I – Preparation. Marcel Dekker-Inc. Mack Publishing Company.S. Evaluation. Philadelphia.II) PRACTICAL 1. New York & Basel. Granules USP/NF coating of granules) III . U. Ansel.

Antiarrhythmics. 2.C. 5. Liebermann & Leon Lachman. Antianginal drugs.A. Philadelphia. 62    . PHARM-363P PHARMACOLOGY-II PRACTICAL 1. Antihyperlipidemics. Drugs Acting on Respiratory System Anti-asthmatic drugs. Herbert A. Respiratory Stimulants.’ C. Manohar A. Oxford University Press. Vit. Anti-tussives & Expectorants. Juliano. K & anticoagulants. Antihypertensive drugs. Angiotensin and Bradykinin Unit-V : Drugs acting on GIT Antacids and Antiulcer drugs. To record the dose response curve (DRC) of Acetylcholine using ileum of Chicken ilium. R. Lea & Febiger. To study the parallel shift of DRC in presence of competitive antagonist on DRC of Ach using Chicken ileum. 5HT and their antagonists. Plasma Volume expanders. Unit-III : NSAIDS & Anti-gout Drugs. Theory & Practice of Industrial Pharmacy. Fibrinolytics & antiplatelet drugs. Thromboxane.Potdar. Prostaglandins. To study the CRC of histamine on guinea pig on ileum preparation & study the effect of Antihistaminics using software.S. Drug Delivery Systems. Laxatives and antidiarrhoeal Agents. Oxford. 6. 4.Diuretics Leukotrienes.GMP for Pharmaceuticals”. Emetics and antiemetics [07] [08] [08] [08] [09] Unit-IV : Autocoids: Histamine. PHARM-363 PHARMACOLOGY-II Unit-I : Pharmacology of CVS: Cardiac glycosides. 3.4. Unit-II : Drugs Acting on Haemopoeitic System Haematinics. To study effect of physostigmine on DRC of each on Chicken ileum. U.

Goodman & Gilman. 10. Dioscorea. Unit. uses. The Pharmacological basis of Therapeutics. C.K. Calcutta. 9. and Stitzel.III : Studies on traditional drugs : Common Vernacular name. Hand Book of Experimental Pharmacology. Solasodine & Podophyllotoxins [03] [03] (B) Production and Utilization of phytoconstituents such as calcium sennsoides.D. Sheffield Bioscience Programms. DR & Bannet PN. Popular Prakashan Pvt. Anthraquinone Cathartics : Aloe. 5. Rang MP. 4. RW Ruddon & AG Gil. Saffron. Fundamentals of Experimental Pharmacology. 12. substitutes and specific chemical tests of following groups of drugs containing. Pharmacology Churchill Livingstone. B. Vallabh Prakashan. 6. Chirata. Saponins : Liquorice. Pharmacology & Pharmacotherapeutics. MN.. Laurence. CBS Publishers. 2. Ghosh. New Delhi.PB Molinoss.. Stropanthus & Thevetia 3. Clinical Pharmacology.. Prentice Hall. ISBN. Editors:-JG Hardman. 63    . Modern Pharmacology. International. 3. R. Ammi majus. Barar FSK : Text Book of Pharmacology. Commercial varieties cultivation. Biological sources.BOOKS RECOMMENDED : 1.1-874758-02-6 PHARM--364 PHARMACOGNOSY – III Unit-I : (A) Study of the biological sources. Bombay. 8. Rhubarb & Cascara. chemical constituents. Gentian. Little Brown and Co. Le Limbird. Katzung. [04] [03] [03] Unit-II : Others : Psoralea. Squill.G. 2. U. Coleus species.. Date MM. New Delhi. Tripathi. Pergamon Press. 1994. Glycosides : 1. Grover J. 11. Jay Pee Publishers. Basic & Clinical Pharmacology. Craig. Riter JM.. Kulkarni S.K. Cardioactive sterols : Digitalis. Interprint. 7.. Essentials of Medical Pharmacology. K. Ltd. Satoskar & Bhandarkar. collection adulterants.K. diagnostic macroscopic and microscopic features n.R. Quassia and Andrographis paniculata.R. Ammi visnaga. New Delhi. Senna. Diosgenin. Ginseng. Delhi. Experiments in Pharmacy & Pharmacology. Churchill Livingstone. Scientific Book Agency.

7. 3. Bhilwa. b) Identification Tests for Guggul lipids. To study the following standards) Loss on drying. Arishtas.Satavari. Guggul. Churnas.morphology. Microscopic study of some important glycoside containing drugs as outlined above. Morphology and microscopy (powder) of Liquorice along with its chemical tests. Shilajit. Tailas. Apamarg. Ammimaius. Siddha and Homeopathic systems of medicines. b) Extractive values. Brahmi. Lehyas and Bhasmas. Nagarmotha. Gutikas. Morphology of Amla. Kalijiri. Palash. 6. Identification of crude drugs listed in theory 2. Standardization of some traditional drug formulations. Lehsun. 9. categories and common uses and toxicological activity of marketed formulations of following indigenous drugs : Amla.III PRACTICAL 1. Gymnema. Chitrak. Morphology of Aloe and chemical tests on Aloe-extracts. pharmacology. Shatavari and Vach. Morphology of Brahmi. Asavas. Vach. [07] Unit-IV : Punarnava. Methi. a) Morphology of Nagarmotha and Neem. Study of powdered drugs. Gokhru. Gokhru. Introduction to Herbal Pharmacopoeia with special reference to. Kantkari. 2. Malkanguni and Neem. 8. Apamarg. Morphology of Psoralia. Unani . Methi. Tulsi. and Shankhpushpi. SUGGESTED PRACTICALS 1. Saffron and Chirata. [07] PHARM-364 P PHARMACOGNOSY . Shankhpushpi. 5. Lehsun and Palash. chemical nature of chief constituents. [08] Unit-V : Brief Introduction and principles of Ayurvedic. Tylophora. Kantkari. Morphology and microscopy (powder) of Rhubarb 4. 64    11 . Rasna. Majith. 3. Morphology of Punarnava.

“Cultivation & utilization of Medicinal plants.” Pharmacognosy & Plant Cultivation” 17. Gokhale AS. Indian Ayurvedic Pharmacopoeia. Atal C.E. 13. 10) in any liquid Ayurvedic formulation.” Pharmacognosy” B. Popular Prakashan (P) Ltd. RRL. T. “Analytical Microscopy” J&A Churchill Ltd. Trease. 6... Qadry J.K. 12. of India. Govt. Jammu. Evans. 15. W. d) pH of 1% solution. Bombay. 65    . Kokate C. Nirali Prakashan. Preparation of medicated oil. Philadelphia. London. I&II. Nadkarni A.. vol. BOOKS RECOMMENDED : 1.E.E. PROJECT WORK A report on marketed preparations based on traditional drugs mentioned in theory. Indian Materia Medica 1-2. New Delhi. Indian council of Medical Reasearch. Indian Herbal Pharmacopoeia. 10. Wallis T. “Text Book of Pharmacognosy” J&A Churchill Ltd. 4. in water and alcohol of any Ayurvedic formulation (solid) available in the market. To perform above studies (exp. U.C.. Compendium of Indian Medicinal Plants I-IV. 11.C. W.K. Raw Materials (All volumes) Council of Scientific & Industrial Research.K. 5. Mohammed Ali. New Delhi. 9. G.E. Wallis..S.K. 3. ICMR & RRL. 10. & Kapur BM. 2. Medicinal plants of India I&II. Indian Pharmacopoeia. 14. Jammu. Tyler V. The wealth of India. & Evans. Gokhale SB. London. 8.Shah Prakashan. Cultivation of Medicinal Plants. “Pharmacognosy” Bailliere Tindall east Baorne. et al : “Pharmacognosy” Lea & Febiger. “Practical Pharmacognosy” Vallabh Prakashan. Rastogi & Malhotra. New Delhi. 11. Kokate CK. 7.S.c) Ash values.

Productivity. 4. Group Discussions (G. Oxford University Press. Corporate behaviour. Leadership Skills.Principles & Practice. Meenakshi & Sharma Sangeeta. Team work ‘BSC’ – Boss. Interview Tips:What student is supposed to do before the interview. Various questions that may be asked in an interview.PHARM-365 PROFESSIONAL COMMUNICATION-II Unit-I 1. Exit Interview BOOKS RECOMMEDNDED 1. Raman. Written skills: Proposal writings formats. [10] [06] [08] [06] [10] 66    . office etiquettes.D) Tips GD Unit-IV 6. during the interview. after the interview & on the day of interview. Technical Communications. 7. Time Management simulation exercise 3. Extempore Unit-V 8. Curriculum Vitae Designing Unit-II 2. Report writings Business letters Applications Covering letters. Subordinates & Collegues Unit-III 5. Model interview (Video-shooting & displaying optional) 9. corporate expectation.

Use. Desert and Aquatic. exploitation and associated problems of forests. types features & functions of difference ecosystems. Biodiversity & its conservation with special reference to India. D. Land resources.Forest Grassland. Marine.C. B. Food resources. utilization. Unit-II Ecosystems A. 1974 Unit-V Environmental Protection Act -1986 Noise Pollution Hazardous Wastes Hazardous Chemical Hazardous Microorganism Biomedical Waste 67    .Natural Resources – renewable & non renewable C. scope & importance B. Lesikar RV. Unit-III Environmental pollution. Nuclear. Introduction. PHARM.2. Tata Mc Graw Hill Co. Water.Definition. Mineral resources. Noise. Soil. Business Correspondence & Report Writing. role of an individual in conservation. Water resources.366 : ENVIRONMENT & ECOLOGY Unit-I Environment studies A. Unit IV Law related to Environmental Protection Air (Prevention and Control of pollution )Act 1987 Water prevention & Control of Pollution Act.Introduction causes and control measures. & Krishna Mohan.Equitable use of resources for sustainable life style.Air. Sharma R. Energy resources. 3. Lesikar’s Basic Business Communication. Thermal.

R. [08] Unit-IIInfra-Red spectrophotometry-Theory. CH3-CHO. ‘ Text Book of Environmental Sciences & Techgnology”. CH3 C6 H5.Trivedy. M. Instrumentation and applications Ultra violet and Visible. instrumentations. mass spectra of some simple compounds. SEMESTER –VII PHAR M–471 PHARMACEUTICAL ANALYSIS -III Unit-I : Colorimetric Method. Pharma Book Syndicate. FTIR. Reference 1. Hyderabad 3. Manoharachary. Instrumentation & Applications. Atomic absorption spectroscopy. Instrumentation and application of GLC & HPLC.Anji . Spectrophotometry. Instrumentation and applications. Reddy.Electronic excitation. 4. Principles of Environmental Studies. Hyderabad. Relevant Acts & Rules published by Govt. deviation from Beer’s law.Inter pretation of IR .Mass Spectroscopy –Theory.NMR. quantitative laws. single and double beam spectrophotometry.Theory. [06] 68    [10] [08] . instrumentation and applications.Chemistry. Unit-IV Flame photometry-Theory . instrumentation. I &II. applications in pharmaceutical analysis. instrumentation and applications Unit-V Basic Principles. Fluorimetric Analysis. Shielding & Desheilding. Acts. C. 2. P. Unit-III NMR Spectroscopy.CH3-(CH2)4 CH3.Theory of 1H. spin spin splitting spectra of CH3-CH2-OH. C6 H6.K. spin spin coupling. Guidelines.Provisions applicable to drugs and cosmetic. spectra of simple compounds. Jyaranama Reddy. Handbook of Environmental Laws. Compliances & Standards Vol. chemical shift. Pharma Book Syndiacte. of India with latest amendments.

Principles of Instrumental Analysis. and Stenlake J. The Athlone Press of the University of London. Skoog V. Practical Pharmaceutical Chemistry Vol. Holler-Neimen PHAR M– 472 PHARMACEUTICS -VIII (BIOPHARMACEUTICS & PHARMACOKINETICS) Unit-1 :Introduction to Biopharmaceutics and Pharmacokinetics and their role in formulation development and clinical setting. Spectrometric Identification of Organic Compounds.B. 6. Jr and Dean J. London 1974. A text book of Pharmaceutical Chemistry Vol. 7. 2. 5. Pharmacopoeia of India.W..G. Undergraduate Instrumental Analysis. and Merrit L. Dekker. New York. Instrumental methods of analysis Van Nostrand Renhold. Absorption Spectroscopy of Organic Molecules Addison-Wesley Publishing Co.R. Obonson J. Marcel Dekker Inc. 1970. 8.H. BOOKS RECOMMENDED 1.PHARM-471P PHARMACEUTICAL ANALYSIS -III PRACTICAL 1. Biopharmaceutics : 69    .A. I & II Marcel. John Wiley & Sons. Ministry of Health.H. New York. Becket A. Assay of at least 10 official formulation containing single and more active ingredients using instrumental techniques. New York. Chatten L. Silver stein RM & Webster FX. Govt of India.H. 2. Interpretation of a few spectra. 3. 4. Willard H. I and II.. Parikh V.

[08] [08] [08] [08] PHARM-472P PHARMACEUTICS-VIII (BIOPHARMACEUTICS & PHARMACOKINETICS) PRACTICAL 1. active transport. Experiments designed for the estimation of various pharmacokinetic parameters with given data. facilitated diffusion and pinocytosis). C-max. 2. (B) Pharmacokinetic drug interactions and their significance in combination therapy. Statistical treatment of pharmaceutical data. 3. (B) Factors influencing absorption – Physicochemical. Loo-Reigelman method. Unit-V :Bioavailability and Bioequivalence : (A) Measures of bioavailability. physiological and pharmaceutical. Determination of pharmacokinetic parameters from plasma and urine data after drug administration by intravascular and oral route. Absorption studies – in vitro. Unit-II : Pharmacokinetics : (A) Significance of plasma drug concentration measurement. and area under the curve (AUC). Unit-III:(A) Volume of distribution and distribution coefficient. (C) Pharmacokinetics of drug absorption – zero order and first order absorption rate constant using Wagner – Nelson. plasma protein binding. 4. Definition and Scope. (B) Compartment kinetics – One compartment and Preliminary information of multicompartment models. In vitro evaluation of different dosage forms for drug release. (B) Compartment model and Non-compartment model. 70    . (C) Drug distribution in the body. (B) Review of regulatory requirements for conduction of bioequivalent studies. (C) Clinical Pharmacokinetics : Definition and scope Unit-IV: (A) Dosage adjustment in patients with and without renal and hepatic failure.(A) Passage of drugs across biological barrier (passive diffusion.

Dispersible etc. Ointment etc. 17.). To determine the various Pharmacokinetic parameters from the given blood data of oral administration of dosge form. To study the effect of formulation on drug release (powder. Capsules. To study the effect of various diluents on dissolution rate of dosage form (Tablets. 13. In-vitro drug release study of the given powder dosage form using various dissolution media. Dissolution Apparatus. To calculate various Pharmacokinetic parameters from the given first order drug release data. 2.). To study the effect of hardness of tablet on dissolution rate. Use of semilog paper. 18. In-vitro drug release study of the given capsule dosage form using various dissolution media. To calculate the various Pharmacokinetic parameters from the given blood data of I. 4.SUGGESTED PRACTICALS 1. 7. In-vitro drug release study of the given film coated dosage form using various dissolution media. 3. To study the in-vitro drug. 16.V bolus. To determine the effect of protein binding on drug bioavailability.drug interaction. Operation of colorimeter & U. To study the passive diffusion of the given drug using egg or goat membrane. To determine the % protein binding of the given drugs.V bolus injection (one compartment model).injection using both methods (Rate of elimination & sigma minus method one compartment model). 14.V spectrophotometer.) dosage form. suspension etc. 19. 12. DEMONSTRATION EXPERIMENTS 1. In-vitro dissolution study of the given sustained release dosage form. 4. 3. To calculate various Pharmacokinetic parameters from the given zero order drug release data. 5. Preparation of Buffers & membranes. 9. 2. 6. In-vitro drug release study of the given uncoated tablet dosage form using different dissolution media.D. 71    . In-vitro dissolution study of the given fast release (M. 11. To study the passive diffusion of the given drug using cellophane membrane. 10. 8. To calculate various Pharmacokinetic parameters from the given urinary excretion data of I. 15.

Clinical Pharmacokinetics.G. opioids.. Tetracyclines. Curry. Robert .Wagner. Estrogens. Progesterone & 72    . Quinolones. Drugs acting on uterus. Fungal infections. Rowland M. R. 6. Milo’ Biopharmaceutics & Clinical pharcokinatics”. Cephalosporins. 3. Calcitonin & Vitamin D. “ Drug Disposition & Pharmacokinetics”. general principles of treatment of poisoning with particular reference to barbiturates. [08] Unit-IV : Chemotherapy of Parasitic infections. Heavy metal Anatagonists. Fundamentals of Clinical Pharmacokinetics. 7. G.G.” Analytical Techniques for Biopharmaceuticals Development”. Unit-III : Chemotherapy General Principles of Chemotherapy. PHAR M– 473 PHARMACOLOGY –III Unit-I : Pharmacology of Endocrine System Hypothalamic & pituitary hormones. N. 8. [10] Unit-V : Principles of Toxicology Definition of poison. 5. Pharmacokinetics for the Pharmaceutical Scientist. Wagner J. Introduction to Immunondulators and Chemotherapy of Cancer. oral hypoglycemic agents & glucagon. Biopharmaceutics and Pharmacokinetics – An introduction Marcel Dekker Inc. organophosphorous & atropine poisoning. Cotrimoxazole. Androgens & anabolic steroids. Drugs Intelligence Publishers. Lea and Febriger. Technomic Publishing A. and Tozer T.N. Gibaldi. Basel. Hamilton. Viral diseases. John. 4. Leprosy. Malaria.E.” Pharmacokinetics for the Pharmaceutical Scientist’. Oral Contraceptives. Tuberculosis. Chloramphenicol. Insulin. Antibiotics – Penicillins. Notari.BOOKS RECOMMENDED : 1.G. Macrolides. Switzerland. Sulfonamides.Y. [07] [07] [08] Unit-II : ACTH & Cortico steroids. Rodriguezdiaz. Wagner J. 2.Y. StephenH. Parathormone. Thyroid hormones & Thyroid Drugs. N.

Grover J. Hand Book of Experimental Pharmacology. Barar F. Goodman & Gilman. Ghosh M.. Hardman. Katzung.III) Mode of action. Prentice Hall. Riter JM. 11. International. Bombay. Jay Pee Publishers. 2. 6. K. Rang MP. Paul. 7.S. Essentials of Medical Pharmacology. Tripathi. All experiments will be conducted using software wherever possible. B.D.PHAR-473P PHARMACOLOGY. three point assay & four point assay. New Delhi. 3. 12. 10. Laurene. Ltd. CBS Publishers. Pharmacology Churchill Livingstone. Satoskar & Bhandarkar : Pharmacology & Pharmacotheropeutics. Experiments in Pharmacy & Pharmacology.K. Editors :. Clinical Pharmacology. New Delhi. Scientific Book Agency.. Le Limbird.K : Text Book of Pharmacology. New Delhi. Delhi. The Pharmacological basis of Therapeutics. Singh. Kulkarni S.. To calculate the pA2 value of Atropine & chlorpheniramine. Interprint. 2. uses . Essentials of Pharmacology. BOOKS RECOMMENDED : 1.Sheffield Bioscience Programs. L.N. PB Molinoss. Fundamentals of Experimental Pharmacology. Popular Prakashan Pvt. 4. Chapman and Hall. 13. DR & Bennet PN. 9. Calcutta.Bioassay of histamine and acetylcholine using matching and interpolation method on rat guinea pig .III PRACTICAL 1. bracketing assay.J.ISBN. 8. Pergamon Press. Unit-I : 73    ..G. Basic & Clinical Pharmacology. RW Ruddon & AG Gil.. 3.K. U. Bioassay of Ach. histamine & oxytocin on suitable isolated preparations using matching assay. structure-activity relationship of the following classes of drug (Synthetic procedures of individually mentioned drugs only). 5. 14. Academa Publishers.K.G. 1-874758-02-6. Vallabh Prakashan. Dale MM. Churchill Livingstone. Surender. Delhi. PHARM –474 PHARMACEUTICAL CHEMISTRY –VI (MEDICINAL CHEMISTRY . Principles of Pharmacology. Pergamon Press.

tetracyclines. Tolbutamide. Antivirals –Amantadine. Methimazole. Philadelphia. Propylthiouracil. Acyclovir. Levothyroxine. Delagado J N and Remers W A R. 3. Diloxanide Antiseptics & Disinfectants – Benzalkonium chloride Anthelmintics. Fluroquinolones.1. Ministry of Health. Pyrimethamine. [08] Unit-II : Antibiotics-Penicillin.. Govt. Eds. Foye W C.Mebendazole Antifungals :.Insulin Chlorpropamide. Primaquine. Principles of Medicinal Chemistry. Estradiol. V. Delhi. 4. Isoniazid. Classification. 5. Unit-V :-Thyroid and Antithyroids – Carbimazole. Dexamethasone.Griseoflain and Clotrimazole Unit-IV : – Anti.Glibenclamide. (C) Adrenocorticoids – Prednisolone. of India. Singh Harkrishan and Kapoor.K. Lamivudine. Chloramphenicol.HIV agents-Zidovudine. Organic Pharmaceutical Chemistry. Stanazolol. Burger’s Medicinal Chemistry. Wolff ME. Vallabh Prakashan. [08] [08] [08] BOOKS RECOMMENDED : 1. John Wiley & Sons. 2. Prostaglandins –Misoprostol. Metformin. Ed. J. New York.. Betamethasone. Pharmacopoeia of India. Hypoglycaemics .Saquinavir. Antiamoebics: Metronidazole. Carboprost. Lippincott Co. Philadelphia. Zalcitabine.. Antimycobacterial Agents:PAS. Ethambutol. Lea & Febiger. Semi-synthetic penicillins. Tinidazole. Nomenclature. Cephalosporins. Steroids and related drugs : Introduction. Stereochemistry (A) Androgens and Anabolic steroids – Testosterone. (B) Estrogens and Progestogens – Progesterone. streptomycin. Dapsone Antimalarials: Cholroquine. Wilson And Gisworld’s Text book of Organic Medicinal and Pharmaceutical Chemistry. 74    .

Vol. Unit-II : (E) Imidazole : Pilocarpus. processing. Taxol. chemical constituents. IV. diagnostic macroscopic& microscopic features & specific chemical tests of following alkaloid containing drugs. 8. collection. Hanch C.6. Ipecac & Opium..Oxford. (C) Quinoline & Isoquinoline : Cinchona. commercial varieties. Coca & Withania. Vol. London. Rauwolfia. Utilization & production of phytoconstituents such as – Tropane Alkaloids. Ipecac. PHARM-475 PHARMACOGNOSY-IV Unit-1 : 1. Oxford University Press. Isoquinoline & Quinoline Alkaloids. Areca & Lobelia. Cinchona. (A) Pyridine-piperidine : Tobacco. Catharanthus & Nux-vomica. Quantitative Drug Design. ELBS/ Longman. 75    [08] [08] . cultivation. uses. Organic Chemistry. Rauwolfia. (D) Indole : Ergot. 7. Comprehensive Medicinal Chemistry. Ginseng. Valerian. Finar I L. (H) Glycoalkaloid : Solanum. Aloe. Nogrady T. Hyoscyamus. Medicinal Chemistry – A Biochemical Approch. (B) Tropane :Belladona. substitutes adulterants. New York. Datura. Systematic study of source. Unit-III (A) World wide trade in Medicinal plants & derived product. Pergamon Press. Papain. Diosgenin. (I) Purines : Coffee & Tea (J) Quinazoline : Vasaka. Tropane alkaloids containing drugs. Digitalis. I & II. & plant laxatives. Liquorice. (F) Steroidal : Veratrum & Kurchi. (G) Alkaloidal amine : Ephedra & Colchicum.Oxford.

(B) Role of Medicinal & aromatic plants in National Economy. classification & study of different chromatographic methods. Chemical test of Nux-vomica. Colchicum. 2. Penicillinase. Chromatographic studies of some herbal constituents. 8. Microscopic study of characters of any 8 selected drugs given in theory in entire and powder form. Chemical test of Tea. Ephedra. 10. Application of plant tissue culture in pharmacognosy. papain. a) Morphology of Areca. b) Transverse section of Catharanthus leaf and Kurchi bark. Plant Bitters & Sweeteners. preparation. 7. To study the morphology and microscopy of Solanum and Vasaka. 11. of chromatographic techniques in evaluation of herbal drugs. [08] [08] Unit-V :Introduction. To study the morphology and microscopy of Catharanthus and Nux-vomica. type of culture. Identificaiton of crude drugs listed above. Chemical evaluation of powdered drugs & Enzymes. To study the morphology and microscopy of Ipecac and Rauwolfia. Datura and Withania. 4. and Kurchi. Hyalluronidase. 5. Unit-IV [08] Biological sources. 5. Introduction of plant-tissue culture techniques on laboratory scale. 2. Tobacco. 9. To study the morphology and microscopy of Datura and Withania. To study the morphology and microscopy of Ephedra and Kurchi. Historical development of plant tissue culture. 4. To study the TLC profile of Catharanthus leaf. To study the TLC profile of Withania root. Identification tests and uses of following enzymes – Diastase. Some experiments in plant tissue culture. 3. 76    . Nutritional requirement. Application PHARM-475P PHARMACOGNOSY -IV PRACTICAL 1. 3. growth & their maintenance. SUGGESTED PRACTICALS 1. 6. Streptokinase.

Analytical Microscopy. S. 17.S.K. “ Pharmacognosy” B. Vyas. 2. The Plant Alkaloids. 7.E. Mohammed Ali. “Pharmacognosy” Bailliere Tindall East Bourne. 5.E. Jammu.” 9. Gokhale AS. Gokhale SB. U. Text book of Pharmacognosy” J&A Churchill Ltd. V. Atal & Kapur. Springer Verlog. Saskatchewan. Henry TA. Cultivation & Utilization of Medicinal Plants. Practical Pharmacognosy. The Pharmaceutical Press. Vallabh Prakashan. Tissue Culture & Plant Science. Pharmaceutical Biotechnology.. London. 10.S.BOOKS RECOMMENDED : 1.E. London.K.E. C. London.K. Street H. Dixit. Academic Press. McGraw Hill. J&A Churchill Ltd. Lea & Febiger Phjadelphia. Tyler V. Cultivation of Medicinal Plants. London. 16. A laboratory handbook. 12.” Pharmacognosy & Plant Cultivation”.K. ND.P. Clarke ECG. National Research Council of Canada. G.. & Evans. W. New York. Trease. Delhi. 4. Stahl. Plant Tissue Culture Methods. Wallis T. Wallis T. 11. 15. Mohammed Ali. C. Ganborg & Wetter. 77    . E. Qadry J. 14. Isolation & Identification of drugs. 8. CBS Publication. 6. Thin Layer Chromatography.Shah Prakashan. Kokate. etal Pharmacognosy.E. Indian Pharmacopoeia.” Pharmacognosy & Phytochemistry”. 13. Nirali Prakashan. Berlin.C. Kokate. 3. RRL.

Fermentor. penicillinase. and humoral immunity. Unit-IV : Microbial Transformation : Introduction. 78    [08] [08] [08] . 3. 2. immune system. Dixit. standardization and storage of BCG. 1987. Ahhitar Principles of Fermentation Technology. S. Antigen and haptens. 4th Ed. Unit-V : Enzyme immobilization : Techniques of immobilization of enzymes. transduction. streptokinase and streptodaranse. conjugation. Vyas and V. Somatotropin. protoplast fusion and gene cloning and their applications. Stanbury & A. [08] Unit-II : Genetic Recombination Transformation. P.SEMESTER – VIII PHARM –481 PHARMACEUTICAL BIOTECHNOLOGY Unit-I : Immunology and Immunological preparations : Principles. [08] Unit-III : Antibiotics : Historical development of antibiotics. CBS Publishers and Distributors. study of enzymes such as hyaluronidase. Pharmaceutical Biotechnology.P. study of drugs produced by biotechnology such as Activase. biotranformation processes and its improvements with special reference to steroids.antigen-antibody reactions and their applications.development of hybridoma for monoclonal antibodies. Delhi. Prescott and Dunn’s Industrial Microbiology. Screening of soil for organisms producing antibiotics Antimicrobial spectrum and methods used for their standardization. Design of Bio-transformation process. Cellular. factors affecting enzyme kinetics. Insulin. New Delhi. its design and control of different parameters. BOOKS RECOMMENDED : 1. types of reactions mediated by microorganisms. CBS Publication. Isolation of mutants and factors affecting mutation. selection of organisms.K. amylases and proteases Immobilization of Bacteria and plant cells. immunological tolerance.F.

7. Whitaker & Hall S.4. D. Crueger W. Menthol. P.J. Unit-IV: Extraction.F. β. Standury & A. Unit-II Extraction. [02] [03] [08] [08] [08] 79    . Isolation & Characterisation of – Terpenoids.Carotene. Principles of Fermentation. 69 Verleg Chernie Switzerland 1984. quinine. Natural Allergens. Biotechnology-A Textbook of Industrial Microbiology. (alkaloids. α-Pinene. ergot. Kieslich Ed. α -Tocopherol. reserpine. terpenes. Diosgenin & Sarasapogenin ii) Lignans iii) Quassinoids iv) Flavonoids (Quercetin) Unit-III : Alkaloids – Atropine & related compounds. Biogenetic Investigations and basic metabolic pathways. 2. New Delhi. Digoxin.Souza. antidiabetics and immunomodulators. 5. Chemical & Spectral approaches to simple molecules of natural origin. Citral. Panima Publishing Corporation.” Biotechnology & Fermentation” PHAR M–482 NATURAL PRODUCTS Unit-I : 1. & Crueger A.Camphor. papaverine.Digitoxin. Photosensitizing agents and fungal toxins. Hecogenin. Unit-V Herbal Cosmetics and their formulation. Aditya Book Private Limited. morphine. K. Recent developments of natural products used as anticancer agents. Delhi. Isolation & Chemistry of – i) Glycosides . ephedrine. and Vinca Alkaloids. steroids) Brief introduction to biogenesis of secondary metabolites of Pharmaceutical importance. 6. Johan. Biotechnology Vol.

(Fresh/ Dry). 6.R. 10. 8.. Finar “Organic chemistry” Vol. 9.K. Stahl E. SUGGESTED PRACTICALS 1. 3. Isolation of Caraway oil from caraway. 5. House. & Evan. “Pharmacognosy” Bailleire tindall East bourne. separation. Isolation of piperine from Black Pepper. 3.. Meerut. U. etal “Pharmacognosy” Lea & Febiger Philadelphia. Tyler V.E. Extraction of volatile oils & theirs chromatographic profiles.L. 6.S.D. London. 4. Harborne. The Practical evaluation of phytopharmaceutical. Isolation of cumin oil from cumin. Isolation of Clove oil from clove. “Practical Pharmacognosy” Vallabh Prakashan. Springer Verlag. I. London. K.B. Qadry. O..PHARM-482P NATURAL PRODUCTS PRACTICAL 1. Pharmacopoeia of India. I & II ELBS. Exercises on paper & thin layer chromatographic evaluations of herbal drug constituents. To perform the column chromatography of herbal drug. To study the TLC profile of extracted oils. To Isolate the active constituent of any available drug with the help of preparative TLC.S. Agarwal. 4. 7.C. Laboratory experiments on Isolation. “Thin layer chromatography” A Laboratory Hand Book.” Pharmaconosy “B. 8. 11. 2. New Delhi. To study the paper chromatographic profile of glycone portion separated from senna. 2. 9. Quantitative determination of Ascorbic acid present in Amla. 5. purification of various groups of chemical Constituents of Pharmaceutical significance. International Ed. I & II Goel Pub.E. Sim.Shah Prakashan. Kokate C. 10.P. Bristol. Isolation of caffeine from Tea leaves.K. Wright. Berlin.. 80    . 3. BOOKS RECOMMENDED 1. 7. J. & Turner T. Brain. Trease G. J. W. 11. Medicinal Plant Alkaloids & Glycosides. 2. Phytochemical Methods Chapman & Hall. “Chemistry of Organic Natural Product” Vol. Isolation of Hesperidin from Orange Peel.

ethics of sales. Margin/ Morale) Principles of Management (Coordination. columns of a cash book. selling. Vandana Publishers. keeping and pricing of stocks. advertising. Entrepreneurship development. Production. training. Salesmanship : Principle of sales promotion. leadership. Unit-III 3. general principles of insurance and inland and foreign trade. Record Keeping). Motivation. Indian Pharmacopoeia. New York. demand curves labor welfare. 15. Communication. profits and loss account. John Wiley & Sons. Academic Press. compensation to the pharmacist. Pharmaceutical Marketing : Functions. promissory notes and bundles documentary bills. Sharma PP. 13.. rectification of errors. 3rd Ed.12. New Jersey. demand schedule. Financial. buying. 14. wholesale. Concept of Management : Administrative Management (Planning. treatment of cheques bills of exchange. Berger’s Medicinal Chemistry & Drug Discibery. storage financed feedback information. purchase. multiple shop and mail order business. detailing. Operative Management (Personnel. Biosynthetic pathway Higher plants. Marketing. evaluation . Decision making. balance sheet. literature. procedure of exporting and importing goods. Manufacturing & Quality control. Pridham JB & Swain T. Recruitment. Innovation Creativity. [03] Accountancy : Principles of Accountancy. Abraham DJ. [04] [04] 81    . channels of distribution. Cosmetics formulation. Delegation of Authority / Responsibility. Materials.483 PHARMACEUTICAL INDUSTRIAL MANAGEMENT Unit-I : 1. merchandising. [12] Unit-II Economics : Principles of economics with special reference to the Laws of demand and supply. Ledger posting and book entries preparation of trial balance. Time/space. department store. [04] 4. Identification of key points to give maximum thrust for development and perfection. Organising Staffing Directing and Controlling). retail. Delhi. Bank reconciliation statement. PHARM. transportation.

6.Vidya Sagar. inventory control and evaluation of materials management. Mukopadhyay Sekhar. Materials Management : A brief exposure of basic principles of management major areas. Process Know-how. scope. purchase. 5. Market Research (A) Measuring & Forecasting Market Demand . Material Management / PHI. Tata Mc Graw Hill. Sterling Publishers. stores. / New Age International. Estimating industry sales. 4. Pharmaceutical Selling. (B) Market segmentation & Market targeting. Essentials of Management. Barthwal R. 8. Estimating current demand Geo-demo-graphic analysis. Industrial Economics –. 7. Chadwick Leslie. Datta A. Chary S.Major concept in demand measurement. Massie L. Production Management : A brief exposure of the different aspects of Production Management – Visible and Invisible inputs. Shreenivasan K.R. 9. Daver Rustam S. [03] [06] 82    . The essence of management accounting / PHI. Pharma Book Syndicate 12. 10.” Pharmaceutical Industrial Management”.Unit-IV 5. Vidya sagar Pharmaceutical Industrial Management. G.R. Unit-V 6.. 11. Weihrich H.K. Maintenance Management. BOOKS RECOMMENDED : 1. Salesmanship and Publicity –/ Vikas. [04] 7. Joseph Essentials of Management / PHI. An Introduction to Industrial Management –/ Vikas. Beri. Market share and future demand.N.. Market Researth – Tata Mc Graw Hill 2. 3. Production and Operative Management / Tata Mc Graw Hill. Koontz H. Methodology of Activities Performance Evaluation Technique Process –Flow.

methods adopted. preparation and revision of hospital formulary. sterilization equipments. procurement and stocking. Unit-III : Central Sterile Supply Unit and their Management: Types of materials for sterilization. manufacturing practice. computerized services (e. demand and costing. Dispensing of drugs to ambulatory patients. personnel requirements. Unit-V: Drug distribution systems in Hospitals : Out-patient dispensing. storage conditions. Manufacture of Sterile and Nonsterile Products: Policy making of manufacturable items. purchase procedures. Responsibilities of a hospital pharmacist. Dispensing of drugs to in-patients. labeling.484 HOSPITAL PHARMACY Unit-I: Organization and Structure: Organization of a hospital and hospital pharmacy.g. packing of materials prior to sterilization. Master formula record . Unit-IV: Drug information service: Sources of information on drugs. Pharmacy and therapeutic committee. procurement of information. Purchase and Inventory control: Principles. 83    . treatment schedules.. Patient medication profile.PHARM. case on drug interaction & adverse reactions. Unit-II : Drug Store Management and Inventory Control: Organization of drug. Retrieval of information. Types of drug distribution systems Charging Policy. idiosyncratic cases etc. Dispensing of controlled drugs. Medication error. Hospital Formulary: Contents. Manufacturing records. MEDLINE). Types of materials stocked. Production control. purchase order. Supply of sterile materials. Records and Reports : Prescription filling drug profile. Budget preparation and implementation.

B. Hasan.S. physical & chemical evaluation of crude drugs. Pharmacy and Drug interactions (D) Pharmaceutical marketing. (E) Pharmaceutical Packaging (f) Novel drug delivery system (G) GMP. organoleptic. Philadelphia. permissible radiation dose level. methods of isotonic tagging. Hospital Pharmacy. a) Anti-inflammatory b) Hypoglycaemic c) Antibacterial 84    [08] [08] [08] [08] Unit-III -Methods of extraction and modern techniques for the isolation. Shah Prakashan.S. 2. purification.radio-active half life. Quality Assurance & Validation (A) STANDARDISATION OF HERBAL DRUGS Unit I – Commerce and quality control of natural medicinal plants products. estimation and characterisation of active plant constituents. Radiation hazards and their prevention. Unit-II . Merchant H. and Qadry J. Production of radio pharmaceuticals.Nuclear Pharmacy : Introduction to Radiopharmaceutics.Standardisation of plant material as per WHO guidelines. microscopical. Text Book of Hospital Pharmacy. (B) Drug design. preparation of radioisotopes in laboratory using radiation dosimetry. preparations. Lea & Febiger. BOOKS RECOMMENDED 1. (C) Clinical. separation Unit-IV -Analysis of official formulations derived from crude drugs including some ayurvedic Unit-V -General methods of screening of natural products for following biological activity: .S. PHARM –485 ELECTIVE Any one of the following: (A) Standardization of herbal drugs. specifications for radio-active laboratory. Ahmedabad. Units of radioactivity. radio-isotope generators.

Robbers J.D. Herbal drug industry (B) DRUG DESIGN Unit-I Introduction to Drug Design.N. Vapoorte. Bioisosterism. Lead Discovery. Elements of chromatography 8. [08] 85    . Evans W. 13. Dhavan B. Pharmacognosy 3.K.R. Clerk’s isolation & identifications of drugs [08] 9.E.E. Swendson Chromatography of alkaloids. Brady Lynn. CDRI Lucknow. [08] Unit-II Drug metabolism-Phase I & Phase II Metabolic Reactions.Text book of Pharmacognosy 4. E. Interactions(Forces) involved in drug receptor complex. Indian herbal pharmacopocia. 6. Lala P.R. Brain K. The use of pharmacological techniques for evaluation of natural products.. and Turner T.C. Trease..C..R. 5.E. Sterochemical aspects in drug design. 10.. The practical evaluation of phytopharmaceuticals 11.d) Antifertility e) Psychopharmacological BOOK RECOMMENDED 1. G. Tyler Varro. 14. & Tracey MV. Wallis T. Mottal.C. Pharmacoepial standards for Ayurvedic formulations CCRAS. Chaudhary.. Physiochemical properties in relation to biological action. Peach K. & Srimal R. Delhi. R.A. Prodrugs & Soft drug concepts [08] Unit-III Analogoues based drug design concept with suitable examples Structure Based drug design concept with examples. Pharmacognosy ELBS. Harborne Phytochemical methods of chemical analysis . 2. 7. British herbal phamacopocia. Modern methods of plant analysis 12.

Marcel Dekker Inc. New York. Quantitative models. 8.Hansch method & Soft ware’s in QSAR. Monitoring an detecting adverse drug reactions.C. New York.” Structure Based Drug Design”.A. Edward C “Computer Assisted Drug Design (American Chemical Society). Pandi Veerapandian. Tests associated with cardiac disorders. renal function. Hematological. E. Lippincott Co. Academic Press.F. Adverse drug reactionEpidemiology. [08] BOOKS RECOMMEDED: 1. M. S. 4. Burger A “A guide to chemical basis of Drug Design “John Wiley & Sons”.J. 3. patient counseling. (C) CLINICAL PHARMACY AND DRUG INTERACTIONS Unit-I INTRODUCTION TO CLINICAL PHARMACY Definition.E. 5. Communication skills including patient medication history interview.Perun <’ Computer aided Drug Design methods Applications”. Wolff. A. New York (1975). Doerge. Valvani.Unit-IV Combinatorial chemistry-Introduction. John Willey and Sons. Ariens: Drug Design. Classification. Philadelphia. Olson. Computer Aided Drug Design-Introduction & Softwares used in CADD [08] Unit-V QSAR Introduction. its structure and use in evaluation of drug therapy. Sinkula and S. parameters. Burger’s Medical Chemistry. Liver function. Salkovisky. 86    .J. R. Physical Chemical Properties of Drugs. Reporting adverse drug reactions. Wilson and Gisvold’s Text Book of Organic Medicinal and Pharmaceutical Chemistry. Parallel and Split & Mixed synthesis. Assessing causality. Risk factors. 6. 2. Thomas J. 7.H. development and scope Unit-II PATIENT DATA ANALYSIS The patient’s case history.

Orient Longman. Renal and non-renal clearance. TDM pharmacist interventions.Dose adjustment in renal failure. Relevant review articles from recent medical and pharmaceutical literature. hepatic dysfunction.Estimation and determinants of bioavailability. John g. Various phases of clinical trials. clinical review.” Pharmacokinetics for the Pharmaceutical Scientist”. 5. 1997.The Society of Hospital Pharmacists of Australia. Williams and Wilkins Publication. 87    ..C. 2.T. Unit. 7. Practice Standrds and Definitions.V CLINICAL PHARMACOKINETICS Physiological determinants of drug clearance and volumes of distribution. ELBS/Churchill Livingstone. 4. 3. Herfindal E. USA. Nyfort-Hansen K. geriatric and paediatric patients.Unit-III DAILY ACTIVITIES OF CLINICAL PHARMACISTS Drug therapy monitoring (Medication chart view.Calculation of loading and maintenance doses. Categories of Phase IV studies. Prentice Hall publication. A Text book of Clinical Pharmacy Practice –Essential Concepts and Skills. Davisson’s Pranciples and Practice of Medicine. and Hirashman J..Quality assurance of clinical Pharmacy services. Nahata M. Clinical Pharmacokinetics-Rowland and Tozer. Inc.Wagner. Biopharmaceutics and Applied Pharmacokinetics-Leon Shargel. Basic skills in interpreting laboratory data.Scott LT. Parthasarthi G. 6.L. REFERENCES 1. Ward round participation Drug utilization evaluation (DUE) and review (DRU). Clinical Pharmacy and Therapeutics Williams and Wilkins 9. 8. American Society of Health System Pharmacists.. Guidelines for good clinical research practice and ethical requirements. Unit-IV RESEARCH DESIGN AND CONDUCT OF CLINICAL TRIALS Research support including planning and execution of clinical trials.

Smith. Retailer. Wholesaler. Mickey C. Pharmacopoeial tests and specifications. Unit-III 5. [08] 88    [08] [08] . Unit-IVDistribution channels in pharmaceutical marketing – Manufacuturer. Stephen. 2. (E) PHARMACEUTICAL PACKAGING Unit-I 1. Unit-V Controls. “Principles of pharmaceutical marketing”. Selection of stockists and distributors. 6. 2. [08] [08] [08] [08] Unit-III Economic and competitive aspects of pharmaceutical industry. 7. Ancillary materials used in packaging. Prescribing habits of physician. (D) PHARMACEUTICAL MARKETING Unit-I Principles of marketing management. Unit-II Drug development and the marketing research interface. Unit-II 3. glass and plastics. Introduction to pharmaceutical marketing.” Biopharmaceutics& clinical pharmacokinatics’.H. Detailing. “ Drug Disposition & Pharmacokinetics”. Kotler. Package systems. package design research. Philip “Marketing Management”.Advertising. 4. Market behaviour. Milo. Defects in packages. Marketing generic drugs. Identification of the marketing. Curry. control of packaging materials. Retail competition. Patient motivation. CBS Publishers & Distributors. metals. Gibaldi. Diversification and specialisation. Testing of containers & closures. Pearson Education Asia. Blister and strip packaging. Packaging materials with special reference to polymers. [08] BOOKS RECOMMENDED 1. Market analysis. 11. Hospital & Government agencies. Stability of package and packaging material.10.Internal control and external control. International marketing. New concepts in pharmaceutical packaging.

Joseph D. 4. 3. Griffin.D. Release and diffusion of drugs from C. [08] [08] BOOKS RECOMMENDED: 1. 5. Medical Device Packaging Handbook. Unit-II 3. Quality-Control of Packaging Materials in Pharmaceutical Industry. Corrugated fibre board materials. Harburn.Unit-IV 8.S. label and leaflets preparation. 6. chemical and biomedical engineering approach to achieve controlled drug delivery. Packaging of Pharmaceuticals. formulation and evaluation. 6. ionotophoresis. kinetics of drug release from microcapsules technology and applications.O.D. Osmotic pumps. Ophthalmic and aerosols. Carriers for drug delivery systems. Microencapsulation: Methods. General methods of design and evaluation of C. Unit-V 10. Implants and inserts: Types. Packaging of Cosmetics and Toiletories. Packaging of Parenterals. Transdermal drug delivery systems: Theory. Drug and cosmetic Packaging. 4. design and evaluation methods.S. Ross. 2. Brien.. Packaging Engineering. [08] [08] [08] 89    . Kac Chensney. Legal requirement.D. Sterilization of packaging materials. 2. Physical. 9. Unit-III 5. Theory of controlled release drug delivery systems. Pointing requirements. Barail. (F) NOVEL DRUG DELIVERY SYSTEM Unit-I 1. Prodrugs.D.

Drug Delivery Systems.raw materials. GLP. Basic concept of quality assurance. An Introduction to buccal. Noxon.Concepts in validation. Novel Drug Delivery Systems. liposomes. 4. Targeted Drug delivery systems: Concept of drug targeting. etc. 7. Sustained and Conrolled Drug Delivery Systems. Microencapsulation.Unit-IV 7. importance in therapeutics. personnel. Ghosh. Jolles and Wooldbridge. Robinson. 3. BOOKS RECOMMENDED 1. CGMP. 11. Advances in drug delivery systems. Forms and maintenance of records in Pharmaceutical industry. containers. Premamoy<’ Polymer Science & Technology”.Protocols. drug immobilization techniques. applications of process validation. [08] [08] (G) GMP. Roiche. Quality assurance systems. 9. neosomes. Documentation. Design of Biopharmaceutical Properties Through Produrugs and Analogs. closures. Drug Design: Facts or Fantasy. 90    [08] [08] . Process validation in manufacturing dosage formulations. Unit-III 4. [08] Unit-II 2. 10. Polymers in Controlled Drug Delivery. Sources and control of quality variation. 2. Deasy. methods in drug targeting. pulmonary colonic delivery. Chien. Requirements of GMP. 3. Julian. environment etc Unit-IV 5. QUALITY ASSURANCE & VALIDATION Unit-I 1. Lisbeth. Gutcho. Microencapsulation and Related Processes. 5. Preparation of documents for new drug approval and export registration. Microencapsulation and Related Processes. WHO guidelines and ISO 9000 series. validation of manufacturing and analytical equipment. nasal. 6. Illum & Davis. Unit-V 8. Robinson and Vincent. Controlled Drug Delivery. USFDA. pharmacosomes and erythrocytes. 8. nanoparticles. ocular.

Willing. Sampling plans. Indian Pharmacopoeia. Tuckerman and Hitchings. United States Pharmacopoeia. 4. BOOKS RECOMMEDED: 1. 6.` 9. OPPI. Loftus and Nash. 7. Quality Assurance Principles for Analytical Laboratories. Garfield. Florey. 5. 7. 2. 3. In process quality control tests. [08] PHAR-485 P Project on Elective   91    .GMP for Pharmaceuticals’. Potdar. Manohar A. British Pharmacopoeia. 8.Unit-V 6. Analytical Profile of Drugs (All volumes). Pharmaceutical Process Validation. Quality Assurance.” C. Sampling and operating characteristics curves. Good Manufacturing Practices for Pharmaceuticals. IPQC problems in pharmaceutical industries.