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Apo-Cloxi , Cloxapen, Cloxilean, Novocloxin , Orbenin, Tegopen Classifications: antiinfective; antibiotic, natural penicillin; beta-lactam
How should I take cloxacillin?
Take cloxacillin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Take cloxacillin on an empty stomach 1 hour before or 2 hours after meals. Do not drink juice or carbonated beverages (soda) with your dose of cloxacillin. These beverages will decrease the effectiveness of the drug. Cloxacillin should be taken at evenly spaced intervals throughout the day and night to keep the level in your blood high enough to treat the infection.
Assessment & Drug Effects Determine previous exposure and sensitivity to penicillins and cephalosporins and other allergic reactions of any kind before treatment is initiated. Monitor for S&S of anaphylactoid reaction (see Appendix G) or other signs or symptoms of hypersensitivity reaction (see Appendix F) as with other penicillins. Lab tests: Periodic assessments of renal, hepatic, and hematopoietic function are advised in patients on long-term therapy. Patient & Family Education Take medication around the clock, do not miss a dose, and continue taking the medication until it is finished. Report to physician the onset of hypersensitivity reaction (see Appendix F) and superinfections. Check with physician if GI adverse effects (nausea, vomiting, diarrhea) appear. Do not breast feed while taking this drug.
Pre-existing CNS depression .Treatment of status epilepticus/ uncontrolled seizures .Produces skeletal muscle relaxation by inhibiting spinal polysynaptic afferent pathways. skeletal muscle relaxants (centrally acting) DOSAGE: 10 mg IM MECHANISM OF ACTION: .Management of the symptoms of alcohol withdrawal CONTRAINDICATIONS: .Skeletal muscle relaxant . . an inhibitory neurotransmitter. anticonvulsants.Cross-sensitivity with other benzodiazepines may occurs . sedative/hyptonics.Comatose patients . .Provides light anesthesia and anterograde amnesia .Depress the CNS.Therapeutic effects: (1) Relief of Anxiety (2) Sedation (3) Amnesia (4) Skeletal muscle relaxant (5) Decreased seizure activity INDICATION: -Adjunct in the management of: 1) Anxiety 2) Preoperative sedation 3) Conscious sedation .GENERIC NAME: Diazepam BRAND NAME: Valium CLASSIFICATION: Antianxiety agents.Has anticonvul-sant properties due to enhanced presynaptic inhibition. probably by potentiating GABA.Hypersensitivity .Uncontrolled severe painUse cautiously in: 1) Hepatic dysfunction 2) Severe renal impairment 3) History of suicide attempt or drug dependence .
CNS: 1) dizziness 2) drowsiness 3) lethargy 4) hangover 5) headache 6) depression . .MISC: 1) physical & psychological depen-dence 2)tolerance NURSING IMPLICATIONS/RESPONSIBILITIES: .EENT: 1) blurred vision .SIDE EFFECTS/ ADVERSE EFFECTS: . The initial dose of diazepam offers seizure control for 15-20 min after .Monitor BP.RESP: 1) respiratory depression .Observe and record intensity.LOCAL: 1) pain (IM) 2) phlebitis (IV) 3) venous thrombosis . PR.DERM: 1) rashes .RR prior to periodically throughout therapy and frequently during IV therapy. diazepam may cause phlebitis and venous thrombosis. duration and location of seizure activity. .CV: 1) hypotension . Observe depressed patients closely for suicidal tendencies.Prolonged high-dose therapy may lead to psychological or physical dependence.Assess IV site frequently during administration. Restrict amount of drug available to patient. .GI: 1) constipation 2) diarrhea 3) nausea 4) vomiting .
. .IM injections are painful and erratically absorbed. control of seizures. If IM route is used. decreased tremulousness. .Effectiveness of therapy can be demonstrated by decrease anxiety level.administration. inject deeply into deltoid muscle for maximum absorption.Caution patient to avoid taking alcohol or other CNS depressants concurrently with this medication. .
Formulation: Each mL contains: magnesium sulfate (anhydrous) = 250mg.s. water for injection. pyrogen-free solution of magnesium sulfate in water for injection. = 1mL. intramuscular dose of up to 20 mL of the undiluted solution may be given (10 mL in each buttock).1 mL per kg body weight injected intramuscularly as needed Pre-eclampsia: 8 to 10 mL added into a 250 mL of 5% dextrose or 0.Generic and brand name: magnesium sulfate 250 mg/mL (25%) solution for injection Category: anticonvulsant Description: magnesium sulfate 250 mg/mL (25%) injection is a sterile.9% sodium chloride injection administered by intravenous infusion. Dosage and administration: Magnesium deficiency. ad. no preservative added Mechanism of action: Magnesium sulfate inhibits convulsion by acting at the myoneural junction to prevent release of acetylcholine and to decrease the motor and plate potential. adult: 2 mL injected intramuscularly every 6 hours for 4 doses Nephritic seizures in children: 0. . q. Indications: magnesium sulfate is indicated for the treatment of acute hypomagnesemia accompanied by signs of tetany. Appropriate reduction in dosage should be made for patients with renal impairment. It is also used to prevent hypomagnesemia in patients receiving total parenteral nutrition (TPN). 8 to 10 mL is injected intramuscularly into alternate buttocks depending on the presence of patellar reflex and adequate respiratory function. It inhibits the contraction of the uterus by directly acting on the myometrial cells and enhancing uterine blood flow. encephalopathy and convulsions and for the prevention and control of convulsions in patients with pre-eclampsia or eclampsia.05 – 0. to control hypertension. Therapy should be continued until paroxysms cease. Thereafter. Simultaneously.
Magnesium Sulfate injection may enhance the effects of neuromuscular blocking agents. Dialysis may be necessary in patients with renal impairment or severe hypermagnesemia. Pharmacokinetics: About one third or orally administered Magnesium Sulfate is absorbed which is enhanced by the presence of the Vitamin D compound Calcitrol. Toxicity in the mother is indicated by the loss of patellar reflex which occurs when the blood level of magnesium is between 7 to 10 mEq/L. sedation and confusion.Note: an isotonic solution of Magnesium Sulfate may be prepared by aseptically adding 7. as gluconate) should always be available for use as antidote. If renal function is normal. Precaution: Use with extreme caution to patients with impaired renal function and those receiving digitalis glycosides. Treatment of Adverse effects: An injectable solution of calcium salt (i. Contraindication: Magnesium Sulfate injection is contraindicated to patients with heart block or myocardial damage. Adverse effects: Adverse effects due to high level of magnesium ion include flushing. muscular weakness. Caution: foods drugs. respiratory paralysis is a potential hazard. hypotension. .e. At 12 to 15 mEq/L. devices and cosmetics act prohibits dispensing without prescription Storage condition: store at temperatures not exceeding 30 degrees Celsius. Availability: magnesium sulfate 250mg/mL (25%) injection is available in clear vials with 10 mL content. deep tendon reflexes are decreased which may be absent at 10mEq/L. It readily crosses the placenta but rarely causes toxicity to the neonate. As the blood level begins to exceed 4 mEq/L. adequate fluid should be given to assist removal of magnesium from the body.3 mL of Magnesium Sulfate 250mg/mL injection to a 50mL of Sterile water for injection of other suitable parenteral solvent. sweating. Calcium salt injection should be administered intravenously at a dose of up to 10mEq to counteract respiratory depression or heart block.
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