Ca|c|um Carbonate

AnLacldsţ AnLlreflux AaenLs Ǝ AnLlulceranLsţ LlecLrolvLesţ Calclum/wlLh vlLamlns

Ind|cat|onť PvperacldlLvm PvperphosphaLaemla ln paLlenLs wlLh chronlc renal fallure
Adm|n|strat|onť
AbsorpLlon mav be lncreased wlLh foodŦ uecreased absorpLlon wlLh branţ foods hlah ln oxalaLes
and whole araln cerealsŦ Calclum mav reduce lron absorpLlonŦ
Mav be Laken wlLh or wlLhouL foodŦ (1ake w/ meals for beLLer absorpLlonŦ Avold Laklna w/ larae
amL of flbreŴrlch foodŦ)
keact|onsť ConsLlpaLlonţ flaLulenceŤ hvpercalcaemlaŤ meLabollc alkaloslsŤ mllkŴalkall svndromeţ LlssueŴ
calclflcaLlonŦ CasLrlc hvpersecreLlon and acld rebound (wlLh prolonaed use)Ŧ
Contra|nd|catedť 8enal lmpalrmenLţ hvpoparaLhvrold dlseaseţ hvpercalcaemlaŴassoclaLed dlseasesŦ
Calclum absorpLlon ls lmpalred ln achlorhvdrlaŤ use an alLernaLe salL and Lake wlLh foodŦ CauLlon
when used ln paLlenLs wlLh a hlsLorv of kldnev sLonesŦ
Mechan|sm of act|onť Calclum carbonaLe can neuLrallse aasLrlc acld rapldlv and effecLlvelvŦ Poweverţ
lL mav adverselv acLlvaLe Ca dependenL processesţ leadlna Lo secreLlon of aasLrlc and hvdrochlorlc
acldŦ lL can lnduce rebound acld secreLlon andţ prolonaed hlah doses mav cause hvpercalcemlaţ
alkalosls and mllkŴalkall svndromeŦ
Absorpt|onť ConverLed Lo calclum chlorlde bv aasLrlc acldŦ Some of Lhe calclum ls absorbed ln
Lhe lnLesLlnesŦ Calclum ls absorbed ln solubleţ lonlzed formŤ solublllLv of calclum ls lncreased ln
an acldlc envlronmenLŦ
D|str|but|onť Crosses placenLaţ enLers breasL mllkŦ
Lxcret|onť Malnlv ln Lhe faeces as unabsorbed calclumŤ urlne (20Ʒ)Ŧ

Interact|onsť CoŴadmlnlsLraLlon wlLh Lhlazlde dlureLlcs or vlL u mav lead Lo mllkŴalkall svndrome and
hvpercalcaemlaŦ uecreased absorpLlon wlLh corLlcosLeroldsŦ uecreases absorpLlon of LeLracvcllnesţ
aLenololţ lronţ qulnolonesţ alendronaLeţ na fluorldeţ Zn and calclumŴchannel blockersŦ Lnhances
cardlac effecLs of dlalLalls alvcosldes and mav preclplLaLe dlalLalls lnLoxlcaLlonŦ

C|met|d|ne
AnLacldsţ AnLlreflux AaenLs Ǝ AnLlulceranLs

Ind|cat|onť 8enlan aasLrlc and duodenal ulceraLlonţ SLress ulceraLlon of upper Cl LracLţ ÞrevenLlon of
acld asplraLlon durlna aeneral anesLheslaţ CasLroŴoesophaaeal reflux dlseaseţ ZolllnaerŴLlllson
svndromeţ nonŴulcer dvspepslaţ Þrophvlaxls of nocLurnal hearLburnţ ÞancreaLlc lnsufflclencv
Adm|n|strat|onť Should be Laken wlLh foodŦ
keact|onsť ularrhoeaţ dlzzlnessţ Llrednessţ rashţ headacheţ CnS dlsLurbancesţ arLhralalaţ mvalalaţ
avnaecomasLlaţ alopoeclaţ blood dvscraslasţ nephrlLlsţ hepaLlLlsţ pancreaLlLlsţ aranulocvLopenlaţ
hvpersenslLlvlLv reacLlonsŦ
Contra|nd|cat|onť PvpersenslLlvlLvţ lacLaLlonţ lmpalred renal and hepaLlc funcLlonŦ Aae ƽ30 vrŤ Cv
lmpalrmenLŦ ÞreanancvŦ
Mechan|sm of act|onť ClmeLldlne compeLlLlvelv lnhlblLs hlsLamlne aL P2ŴrecepLors of Lhe aasLrlc
parleLal cells resulLlna ln decreased aasLrlc acld secreLlonţ aasLrlc volume and hvdroaen lon
concenLraLlonŦ lL ls a poLenL lnhlblLor of meLabollsm ln Lhe hepaLlc mlxedŴfuncLlon oxldase svsLemsŦ lL
ls also used ln paLlenLs wlLh pancreaLlc lnsufflclencv Lo reduce Lhe breakdown of pancreaLlc enzvme
supplemenLsŦ
Absorpt|onť 8eadllv absorbed from Lhe Cl LracLŤ peak plasma concenLraLlons afLer 1Ŵ3 hrŦ lood
delavs Lhe raLe and sllahLlv decreases exLenL of absorpLlonŦ
D|str|but|onť Jldelv dlsLrlbuLed ln Lhe bodvŤ crosses Lhe placenLal barrler and appears ln breasL
mllkŦ ÞroLelnŴblndlnať 20ƷŦ
Metabo||smť ÞarLlallv hepaLlcŤ converLed Lo Lhe sulfoxlde and Lo hvdroxvmeLhvlclmeLldlneŦ

Interact|onť AbsorpLlon reduced bv anLacldsŦ Mav poLenLlaLe anLlcoaaulanLsţ phenvLolnţ Lheophvlllneţ
benzodlazeplnesţ ĒŴblockersţ lldocalneŦ Þrocalnamlde clearance ls reducedŦ 8educed absorpLlon of
keLoconazole and lLraconazoleŦ Mav enhance aasLrlc mucosal lrrlLaLlon when Laken wlLh eLhanolŦ
Avold concurrenL use wlLh clopldoarelŦ



Cora|an
AnLlŴAnalnal uruas Ŷ cardlac preparaLlon (lvabradlne)

Ind|cat|onť SvmpLomaLlc LreaLmenL of chronlc sLable analna pecLorls ln coronarv arLerv dlsease
paLlenLs w/ normal slnus rhvLhmŦ ÞaLlenLs unable Lo LoleraLe or w/ a Cl Lo Lhe use of ĒŴblockersŤ or ln
comblnaLlon w/ ĒŴblockers ln paLlenLs lnadequaLelv conLrolled w/ an opLlmal ĒŴblocker dose Ǝ whose
hearL raLe ls ƽ60 bpmŦ
Dosageť 3 ma bldŦ AfLer 1 mLhţ lncrease Lo 7Ŧ3 ma bldŦ £/der/y 2Ŧ3 ma mornlna Ǝ evenlnaŦ
Conta|nd|cat|onť 8esLlna hearL raLe Ƽ60 bpm prlor Lo LreaLmenLţ cardloaenlc shockţ acuLe Mlţ severe
hvpoLenslon (Ƽ90/30 mmPa)ţ severe hepaLlc lnsufflclencvţ slck slnus svndromeţ SA blockţ severe
hearL fallureţ pacemakerŴdependenL paLlenLţ unsLable analnaţ 3rd dearee AvŴblockŦ ConcomlLanL
poLenL C?Þ3A4 lnhlblLorsŦ Þreanancv Ǝ lacLaLlonŦ
Mechan|sm of act|onť lvabradlne ls a pure hearL raLeŴlowerlna aaenLţ acLlna bv selecLlve and speclflc
lnhlblLlon of Lhe cardlac pacemaker lf currenL LhaL conLrols Lhe sponLaneous dlasLollc depolarlsaLlon
ln Lhe slnus node and reaulaLes hearL raLeŦ 1he cardlac effecLs are speclflc Lo Lhe slnus node wlLh no
effecL on lnLraŴaLrlalţ aLrlovenLrlcular or lnLravenLrlcular conducLlon Llmesţ nor on mvocardlal
conLracLlllLv or venLrlcular repolarlsaLlonŦ
Adverse react|onť Lumlnous phenomena (phosphenes)ţ blurred vlslonţ bradvcardlaţ 1sL dearee Av
blockţ venLrlcular exLrasvsLolesţ headacheţ dlzzlnessŦ








C|ar|cort
AnLlhlsLamlnes Ǝ AnLlalleralcs

Ind|cat|onť 8ellef of svmpLoms of aLoplc dermaLlLlsţ analoedemaţ urLlcarlaţ seasonal Ǝ perennlal
alleralc rhlnlLlsţ food Ǝ drua alleralc reacLlonŦ
Dosageť AdulL Ǝ chlldn ƽ12 vr 1 Lab bld
Contra|nd|cat|onť PvpersenslLlvlLv Lo loraLadlne or beLameLhasoneŦ 8eLameLhasoneť SvsLemlc funaal
lnfecLlonsŦ
Mechan|sm of act|onť AnLlhlsLamlneŦ AnLlŴlnflammaLorvŦ
8v uslna loraLadlneŴbeLameLhasone ln comblnaLlonţ LableLs comblne Lhe anLlŴlnflammaLorv and
anLlalleralc effecL of Lhe corLlcosLerold (beLameLhasone) wlLh Lhe nonsedaLlna anLlhlsLamlne
(loraLadlne)Ŧ
LoraLadlne ls a poLenL lonaŴacLlna Lrlcvcllc anLlhlsLamlne wlLh selecLlve perlpheral P1ŴrecepLor
anLaaonlsLlc acLlvlLvŦ
ClucocorLlcosLerolds eaţ beLameLhasoneţ cause profound and varled meLabollc effecLs and modlfv
Lhe bodvƌs lmmune response Lo dlverse sLlmullŦ
8eLameLhasone has hlah alucocorLlcosLerold acLlvlLv and sllahL mlneralocorLlcosLerold acLlvlLvŦ
Adverse keact|onť laLlaueţ headacheţ somnolenceţ nervousnessţ drv mouLhţ Cl dlsorders (ea nauseaţ
aasLrlLls) Ǝ alleralc svmpLoms ea rashŦ








Amox|c||||n
Þenlcllllns

Ind|cat|onť 8lllarv LracL lnfecLlonsţ LndocardlLlsţ Conorrhoeaţ CLlLls medlaţ AcLlnomvcoslsţ
Þneumonlaţ 8ronchlLlsţ 1vphold and paraLvphold feverţ CasLroenLerlLlsţ Lvme dlseaseţ MouLh
lnfecLlonsţ Spleen dlsordersţ urlnarv LracL lnfecLlonsţ Þrophvlaxls of endocardlLlsţ Severe or recurrenL
resplraLorv LracL lnfecLlonsţ nŦpvlotl lnfecLlonţ SuscepLlble lnfecLlonsţ LlsLerlal menlnalLls
Mechan|sm of act|onť Amoxlclllln lnhlblLs Lhe flnal LranspepLldaLlon sLep of pepLldoalvcan svnLhesls
ln bacLerlal cell wall bv blndlna Lo one or more of Lhe penlcllllnŴblndlna proLelns (Þ8Þs)ţ Lhus lnhlblLlna
cell wall blosvnLhesls resulLlna ln bacLerlal lvslsŦ
Adverse react|onť PvperacLlvlLvţ aalLaLlonţ lnsomnlaţ dlzzlnessŤ maculopapular rashţ exfollaLlve
dermaLlLlsţ urLlcarlaţ hvpersenslLlvlLv vascullLlsŤ dlarrhoeaţ nauseaţ vomlLlnaŤ anaemlaţ
LhrombocvLopenlaţ leucopenlaţ aaranulocvLoslsŦ
Þotent|a||y Iata|ť neuromuscular hvpersenslLlvlLvŤ pseudomembranous collLlsŦ

5a|butamo|
AnLlasLhmaLlc Ǝ CCÞu ÞreparaLlonsţ uruas AcLlna on Lhe uLerus

Mechan|sm of Act|onť SalbuLamol ls a dlrecLŴacLlna svmpaLhomlmeLlc wlLh ĒŴadreneralc acLlvlLv and
selecLlve acLlon on Ē2 recepLorsţ produclna bronchodllaLlna effecLsŦ lL also decreases uLerlne
conLracLlllLvŦ
Ind|cat|onť bronchospasm
Dosageť Should be Laken on an empLv sLomachŦ (1ake 1 hr before or 2 hr afLer mealsŦ)
Contra|nd|cat|onť Lclampsla and severe preŴeclampslaŤ lnLraŴuLerlne lnfecLlonţ lnLraŴuLerlne foeLal
deaLhţ anLeparLum haemorrhaaeţ placenLa praevla and cord compresslonţ LhreaLened mlscarrlaaeţ
cardlac dlseaseŦ
5|de Lffectsť Mav lead Lo Lachvcardlaţ Lremorţ CnS sLlmulaLlonţ hvpokalaemla and hvperalvcaemlaŦ
SvmpLomaLlc LreaLmenL ls recommended(overdose)
llne skeleLal muscle Lremor especlallv handsţ Lachvcardlaţ palplLaLlonsţ muscle crampsţ
headacheţ paradoxlcal bronchospasmţ analoedemaţ urLlcarlaţ hvpoLenslon and collapseŦ
ÞoLenLlallv serlous hvpokalaemla afLer larae dosesŦ















Þaracetamo|
Analaeslcs (nonŴCplold) Ǝ AnLlpvreLlcs

Ind|cat|onť Mlld Lo moderaLe paln and feverŦ
Dosageť Mav be Laken wlLh or wlLhouL foodŦ
Mechan|sm of act|onť ÞaraceLamol exhlblLs analaeslc acLlon bv perlpheral blockaae of paln lmpulse
aeneraLlonŦ lL produces anLlpvresls bv lnhlblLlna Lhe hvpoLhalamlc heaLŴreaulaLlna cenLreŦ lLs weak
anLlŴlnflammaLorv acLlvlLv ls relaLed Lo lnhlblLlon of prosLaalandln svnLhesls ln Lhe CnSŦ
Adverse keact|onť nauseaţ alleralc reacLlonsţ skln rashesţ acuLe renal Lubular necroslsŦ
Þotent|a||y Iata|ť verv rareţ blood dvscraslas (eŦaŦ LhrombocvLopenlaţ leucopenlaţ
neuLropenlaţ aaranulocvLosls)Ť llver damaaeŦ





Aprove|
AnaloLensln ll AnLaaonlsLs Ŷ lrbesarLan

Ind|cat|onť lor Lhe LreaLmenL of essenLlal P1n Ǝ LreaLmenL of renal dlsease ln paLlenLs w/ P1n Ǝ
Lvpe ll dlabeLes melllLusţ as parL of an anLlhvperLenslve drua realmenŦ
Dosageť 130 ma dallvŦ Mav be lncreased Lo 300 ma or comblned w/ oLher anLlhvperLenslve aaenLs lf
paLlenL ls noL sufflclenLlv conLrolledŦ emodio/yted potients Ǝ e/der/y ƽ75 yr 73 ma dallv lnlLlallvŦ
Contra|nd|cat|onť Þreanancvţ 2
nd
Ǝ 3
rd
LrlmesLer Ǝ lacLaLlonŦ
Mechan|sm of act|onť lrbesarLan ls a poLenLţ orallv acLlveţ selecLlve analoLensln ll recepLor (Lvpe A11)
anLaaonlsLŦ lL ls expecLed Lo block all acLlons of analoLensln ll medlaLed bv Lhe A11 recepLorţ
reaardless of Lhe source or rouLe of svnLhesls of analoLensln llŦ 1he selecLlve anLaaonlsm of Lhe
analoLensln ll (A11) recepLors resulLs ln lncreases ln plasma renln levels and analoLensln ll levelsţ and
a decrease ln plasma aldosLerone concenLraLlonŦ Serum poLasslum levels are noL slanlflcanLlv affecLed
bv lrbesarLan alone aL Lhe recommended dosesŦ lrbesarLan does noL lnhlblL ACL (klnlnaseŴll)ţ an
enzvme whlch aeneraLes analoLenslnŴll and also dearades bradvklnln lnLo lnacLlve meLabollLesŦ
lrbesarLan does noL requlre meLabollc acLlvaLlon for lLs acLlvlLvŦ
Adverse keact|onť MusculoskeleLal Lrauma Ǝ flushlnaŦ














Þ|ogre|
AnLlcoaaulanLsţ AnLlplaLeleLs Ǝ llbrlnolvLlcs (1hrombolvLlcs) Ŷ Clopldoarel

Ind|cat|onť lor prevenLlon of arLheroscleroLlc evenLs ln paLlenLs w/ť PlsLorv of recenL Mlţ recenL
lschemlc sLroke or esLabllshed perlpheral arLerlal dlsease or nonŴS1 seamenL elevaLlon acuLe coronarv
svndrome lncludlna paLlenLs w/ percuLaneous coronarv lnLervenLlon Ǝ coronarv arLerv bvpass arafLŦ
Clven prophvlacLlcallv as an alLernaLlve Lo asplrln ln paLlenLs aL rlsk of Lhromboembollc dlsordersŦ
Dosageť Mlţ sLrokeţ perlpheral arLerlal dlsease Ǝ prophvlaxls of Lhroembollc evenLs 73 ma once dallvŦ
unsLable analna/nonŴCŴwave Ml Loadlna doseť 300 ma as slnale doseŦ ConLlnue 73 ma once dallv ln
comblnaLlon w/ asplrlnŦ
Contra|nd|cat|onť ÞepLlc ulcerţ lnLracranlal hemorrhaae or coaaulaLlon dlsordersŦ ChlldnŦ
Mechan|sm of act|onť Clopldoarel ls an lrreverslble lnhlblLor of plaLeleL aaareaaLlonŦ lL acLs bv
lrreverslblv modlfvlna Lhe plaLeleL adenoslne 3ƌŴdlphosphaLe (AuÞ) recepLorţ Lhus selecLlvelv
lnhlblLlna Lhe blndlna of AuÞ Lo lLs plaLeleL recepLor and Lhe subsequenL acLlvaLlon of Lhe
alvcoproLeln CÞllb/llla complexţ Lherebv lnhlblLlna plaLeleL aaareaaLlonŦ ConsequenLlvţ plaLeleLs
exposed Lo clopldoarel are affecLed for Lhe remalnder of Lhelr llfespanŦ 8loLransformaLlon of
clopldoarel Lo lLs acLlve meLabollLe ls necessarv Lo produce lnhlblLlon of plaLeleL aaareaaLlonŦ
Adverse react|onť 8leedlnaţ hemorrhaaeŦ









Vastare|
AnLlŴAnalnal uruas

Ind|cat|onť LonaŴLerm LreaLmenL of coronarv lnsufflclencvŤ analna pecLorlsŦ
Should be Laken wlLh food
Contra|nd|cat|onť LacLaLlonŦ
Mechan|sm of act|onť MeLabollc anLlŴlschemlc aaenLŦ 1rlmeLazldlne ls a meLabollc aaenLţ a speclflc
and selecLlve lnhlblLor of Lhe 3ŴkA1Ŧ 1hls lnhlblLlon of ĒŴoxldaLlon allows a recoupllna of alvcolvsls and
an lncrease ln alucose oxldaLlon for beLLer enerav producLlon under lschemlc condlLlonsŦ8v
preservlna Lhe enerav meLabollsm ln cells exposed Lo hvpoxla or lschemlaţ LrlmeLazldlne prevenLs a
decrease ln lnLracellular A1Þ levelsţ Lherebv ensurlna Lhe proper funcLlonlna of lonlc pumps and
Lransmembranous sodlumŴpoLasslum flow whllsL malnLalnlna cellular homeosLaslsŦ
O ln manţ conLrolled sLudles ln analna paLlenLs have shown LhaL LrlmeLazldlne lncreases
coronarv reserveţ Lherebv delavlna Lhe onseL of lschemla assoclaLed wlLh exerclseţ sLarLlna
from Lhe 13Lh dav of LreaLmenLţ slanlflcanLlv decreases Lhe frequencv of analna aLLacks
and leads Lo a slanlflcanL decrease ln Lhe use of nlLraLesŦ
Adverse and 5|de Lffectsť 8are cases of aasLrolnLesLlnal dlsordersŦ












5erc Ŵ 8etah|st|ne
AnLlverLlao uruas

Ind|cat|onť Menlereƌs dlseaseţ MenlereŴllke svndrome characLerlzed bv aLLacks of verLlaoţ LlnnlLus Ǝ
sensorlneural deafnessţ perlpheral verLlaoŦShould be Laken wlLh food
Mechan|sm of Act|onť Serc exerLs a relaxanL acLlon on Lhe precaplllarv sphlncLers of Lhe
mlcroclrculaLlon of Lhe lnner earţ and Lherebv lncreases Lhe blood supplv Lo Lhe sLrla vascularls of Lhe
labvrlnLhŦ lnvesLlaaLlons lnLo Lhe acuLeţ subacuLe and chronlc effecLs of beLahlsLlne ln anlmals have
demonsLraLed Lhe low LoxlclLv and safeLv of Lhe druaŦ
Contra|nd|cat|onť PvpersenslLlvlLv Lo beLahlsLlne dlPCl or Lo anv of Lhe exclplenLs of SercŦ ÞaLlenLs
wlLh phaeochromocvLoma or bronchlal asLhma should be LreaLed wlLh exLra careŦAlLhouah no causal
connecLlon has been shown beLween Serc LreaLmenL and relapses of pepLlc ulcerţ lL ls recommended
Lo use Serc wlLh cauLlon ln paLlenLs wlLh a hlsLorv of pepLlc ulcerŦ
Adverse and s|de Lffectsť Mlld aasLrlc complalnLs Ŵ ellmlnaLed bv reduclna Lhe dosaaeŦ
Skln rashes
Levof|oxac|n
Culnolonesţ Lve AnLlŴlnfecLlves Ǝ AnLlsepLlcs

Mechan|sm of Act|onť Levofloxacln exerLs anLlbacLerlal acLlon bv lnhlblLlna bacLerlal Lopolsomerase
lv and unA avraseţ Lhe enzvmes requlred for unA repllcaLlonţ LranscrlpLlon repalr and
recomblnaLlonŦ lL has ln vlLro acLlvlLv aaalnsL a wlde ranae of aramŴneaaLlve and aramŴposlLlve
mlcrooraanlsmsŦ
Ind|cat|onť AcuLe bacLerlal slnuslLlsţ AcuLe bacLerlal exacerbaLlon of chronlc bronchlLlsţ CommunlLvŴ
acqulred pneumonlaţ nosocomlal pneumonlaţ skln and skln sLrucLure lnfecLlonsţ urlnarv LracL
lnfecLlonsţ AcuLe pvelonephrlLlsţ Chronlc bacLerlal prosLaLlLlsţ 1reaLmenL and posLexposure
prophvlaxls of lnhalaLlon anLhraxţ Ccular lnfecLlons
O 1abť Mav be Laken wlLh or wlLhouL foodŦ (Lnsure adequaLe fluld lnLakeŦ)
O Cral solnť Should be Laken on an empLv sLomachŦ (1ake on an empLv sLomach 1 hr before
or 2 hr afLer mealsŦ Lnsure adequaLe fluld lnLakeŦ)
Contra|nd|cat|onť PvpersenslLlvlLv Lo levofloxacln or oLher qulnolonesŦ Chlld Ƽ18 vrŦ
5|de Lffectsť nauseaţ dlarrhoeaţ consLlpaLlonţ headacheţ lnsomnlaţ ln[ slLe reacLlons (lv)Ŧ CphLhalmlcť
1ranslenL decrease ln vlslonţ ocular burnlnaţ ocular paln or dlscomforLţ forelan bodv sensaLlonţ
headacheţ feverţ pharvnalLlsţ phoLophobla
Adverse Lffectsť Anaphvlaxls











Lrdoste|ne
Couah Ǝ Cold ÞreparaLlons

Ind|cat|onť MucolvLlc
Mechan|sm of Act|onť LrdosLelne conLalns Lwo sulfhvdrvl aroupsţ whlch are freed afLer meLabollc
LransformaLlon ln Lhe llverŦ 1he llberaLed sulfhvdrvl aroups break Lhe dlsulphlde bondsţ whlch hold
Lhe alvcoproLeln flbres of mucus LoaeLherŦ 1hls makes Lhe bronchlal secreLlons more fluld and
enhances ellmlnaLlonŦ
Contra|nd|cat|onť AcLlve pepLlc ulcerŦ
5|de Lffectsť LplaasLralalaţ nauseaţ vomlLlnaţ loose sLoolsţ spasmodlc collLlsţ headacheŦ





2|thromax
Macrolldes

Ind|cat|onť upper Ǝ lower resp LracL lnfecLlonsţ skln Ǝ sofL Llssue lnfecLlonsţ oLlLls medlaţ S1u due Lo
Chlamvdla LrachomaLls Ǝ aenlLal lnfecLlons due Lo nonŴmulLlreslsLanL nelsserla aonorrhoeaeŦ
Þrophvlaxls aaalnsL MvcobacLerlum avlumŴlnLracellulare complex (MAC) lnfecLlon ln paLlenLs w/
advanced PlvŦ pelvlc lnflammaLorv dlsease ln paLlenLs who requlre lnlLlal lv LherapvŦ AcuLe bacLerlal
exacerbaLlons of chronlc bronchlLls due Lo PŦ lnfluenzaţ Moraxella caLarrhallsţ MŦ pneumonlae or SŦ
pneumonlaeŦ ÞharvnalLls/LonsllllLls caused bv SŦ pvoaenesŦ AcuLe bacLerlal slnuslLls due Lo PŦ
lnfluenzaeţ MŦ caLarrhallsţ PŦ paralnfluenzae or SŦ pneumonlaeŦ CommunlLvŴacqulred pneumonla due
Lo CŦ pneumonlaeţ PŦ lnfluenzaeţ PŦ paralnfluenzaeţ MŦ caLarrhallsţ MŦ pneumonlae or SŦ pneumonlaeŦ
Mav be Laken wlLh or wlLhouL food (Mav be Laken w/ meals Lo reduce Cl dlscomforLŦ)Ŧ
Mechan|sm of Act|onť 1he mechanlsm of acLlon of azlLhromvcln ls lnhlblLlon of proLeln svnLhesls ln
bacLerla bv blndlna Lo Lhe 30S rlbosomal subunlL and prevenLlna LranslocaLlon of pepLldesŦ
Contra|nd|cat|onť PvpersenslLlvlLv Lo macrolldesŦ
5|de Lffectsť nauseaţ abdomlnal dlscomforLţ vomlLlnaţ flaLulenceţ dlarrhea Ǝ loose sLoolsŦ Pearlna
lmpalrmenLţ lnLersLlLlal nephrlLlsţ acuLe renal fallureţ abnormal llver funcLlonţ dlzzlness/verLlaoţ
convulslonsţ headacheţ somnolenceţ reduced lvmphocvLe counLţ lncreased eoslnophll counLţ reduced
blood blcarbonaLeŦ Analoedemaţ anaphvlaxlsŦ











Þantoprazo|e
AnLacldsţ AnLlreflux AaenLs Ǝ AnLlulceranLs (proLon pump lnhlblLor Ŵ used ln Lhe LreaLmenL of pepLlc
ulcer and aasLroŴoesophaaeal reflux dlsease (CL8u)Ŧ

Ind|cat|onť CasLroŴoesophaaeal reflux dlseaseţ ÞepLlc ulcerţ nŦpvlotl lnfecLlonţ Þrophvlaxls of nSAluŴ
lnduced ulcersţ ZolllnaerŴLlllson svndrome
Mechan|sm of Act|onť ÞanLoprazole lnhlblLs P
+
/k
+
A1Þase pump funcLlon Lherebv reduclna aasLrlc
acld secreLlonŦ lL also has a role ln Lhe eradlcaLlon of PŦ pvlorlŦ
Contra|nd|cat|onť LacLaLlon
5|de Lffectsť ularrhoeaţ dlzzlnessţ prurlLusţ skln rashesţ Cl LracL lnfecLlonsţ chesL palnţ headacheţ
nauseaţ palnţ anxleLvţ hvperalvcaemlaŤ malalse or lasslLudeŤ mvalalaŤ oedemaŤ lnsomnlaŤ
hvperllpldaemlaŤ flaLulenceţ abdomlnal palnţ consLlpaLlonţ erucLaLlonţ dvspepslaţ recLal dlsorderŤ
urlnarv frequencvţ u1lŤ abnormallLles ln llver funcLlonŤ local slLe reacLlonŤ hvperLonlaţ neck palnţ
weaknessŤ bronchlLlsţ couahţ dvspnoeaţ pharvnalLlsţ rhlnlLlsţ slnuslLlsţ upper resplraLorv LracL
lnfecLlonţ flu svndromeŦ
Adverse Lffectsť
noL removed bv haemodlalvsls
Lona Lerm use (ƽ3 vr) mav lead Lo vlLamln 812 malabsorpLlonŦ
Mav decrease oral absorpLlon of lron salLsŦ
normal releaseť Mav be Laken wlLh or wlLhouL foodŦ
ConLrolledŴreleaseť Should be Laken on an empLv sLomachŦ (1ake 1 hr before mealsŦ
Swallow wholeţ do noL chew/crushŦ)
LonaŴLerm Lherapv mav lead Lo bacLerlal overarowLh ln Lhe Cl LracLŦ
PepaLlc lmpalrmenLŤ monlLor llver funcLlon reaularlv (lf enzvmes lncreaseţ dlsconLlnue)
noL recommended ln chlldren Ƽ18 vrŤ lona Lerm use mav lead Lo aLrophlc aasLrlLlsŦ
Mav produce false poslLlve urlne screenlna LesLs for LeLrahvdrocannablnolŦ




I|u|muc||
Couah Ǝ Cold ÞreparaLlons Ŷ mucolvLlcs

Ind|cat|onť AcuLe Ǝ chronlc resp LracL affecLlons w/ abundanL mucus secreLlonsŦ
Adm|n|strat|onť Should be Laken wlLh food
Contentsť LffervescenL Lab/SacheL ÞhenvlkeLonurlcsŦ
Adverse keact|onsť 8arelvţ urLlcarlaţ bronchospasmţ nauseaţ vomlLlnaŦ Aerosol LreaLmenLť 8hlnlLlsţ
sLomaLlLlsŦ







ka||um duru|e
LlecLrolvLes Ŵ poLasslumŴconLalnlna preparaLlons

Contentsť kCl (equlv Lo 9Ŧ8 mLq) 730 ma
Ind|cat|onť PvpokalemlaŦ Þrophvlaxls durlna LreaLmenL w/ dlureLlcsŦ
Adm|n|strat|onť Should be Laken wlLh food (Swallow whole w/
1
/2 alass of llqdţ do noL
break/chew/crushŦ uo noL admlnlsLer Lo a paLlenL ln a suplne poslLlonŦ)Ŧ
Contra|nd|cat|onť 8enal lnsufflclencvţ hvperkalemlaţ unLreaLed Addlsonƌs dlseaseţ consLrlcLlon of Lhe
esophaaus Ǝ/or obsLrucLlve chanaes ln Lhe allmenLarv LracLŦ






Az|thromyc|n
Macrolldes Ŵ svsLemlc lnfecLlonsŦ

Ind|cat|onť Skln and sofL Llssue lnfecLlonsŤ 8esplraLorv LracL lnfecLlonsŤ uncompllcaLed aenlLal
lnfecLlons due Lo Chlamvdla LrachomaLlsŤ uncompllcaLed aonorrhoeaŤ Þrophvlaxlsof dlssemlnaLed
MvcobacLerlum avlum complex (MAC) lnfecLlonsŤ Cranuloma lnaulnaleŤ AcLlve lmmunlsaLlon aaalnsL
Lvphold fever caused bv Salmonella Lvphl
Adm|n|strat|onť
1abť Mav be Laken wlLh or wlLhouL foodŦ (Mav be Laken w/ meals Lo reduce Cl dlscomforLŦ)
Suspť Mav be Laken wlLh or wlLhouL foodŦ (Mav be Laken w/ meals Lo reduce Cl dlscomforLŦ)
Capť Should be Laken on an empLv sLomachŦ (1ake on an empLv sLomach 1 hr before or 2 hr afLer
mealsŦ)
Contra|nd|cat|onť PvpersenslLlvlLvŦ
Adverse react|onť Mlld Lo moderaLe nauseaţ vomlLlnaţ abdomlnal palnţ dvspepslaţ flaLulenceţ
dlarrhoeaţ cramplnaŤ analoedemaţ cholesLaLlc [aundlceŤ dlzzlnessţ headacheţ verLlaoţ somnolenceŤ
LranslenL elevaLlons of llver enzvme valuesŦ
Mechan|sm of act|onť AzlLhromvcln blocks LranspepLldaLlon bv blndlna Lo 30s rlbosomal subunlL of
suscepLlble oraanlsms and dlsrupLlna 8nAŴdependenL proLeln svnLhesls aL Lhe chaln elonaaLlon sLepŦ










Levopront Ŵ Levodroprop|z|ne
Couah Ǝ Cold ÞreparaLlons Ŵ couah suppressanLsŦ

Ind|cat|onť SvmpLomaLlc LreaLmenL of couahŦ
Adm|n|strat|onť Should be Laken on an empLv sLomach (1ake beLween mealsŦ)Ŧ
Contra|nd|cat|onť ÞaLlenLs w/ excesslve dlscharae of mucusţ w/ llmlLed mucoclllarv funcLlonţ severe
llver dvsfuncLlonŦ Þreanancvţ lacLaLlonŦ Chlldn Ƽ24 mLhŦ
Adverse react|onť Cl effecLsţ exhausLlonţ falnLnessţ somnolenceţ cloudlna of consclousnessţ
numbnessţ dlzzlnessţ headacheţ palplLaLlonsŦ 8arelvţ alleralc reacLlonsŦ






ketoro|ac
nonsLeroldal AnLlŴlnflammaLorv uruas (nSAlus)ţ CphLhalmlc ueconaesLanLsţ AnesLheLlcsţ AnLlŴ
lnflammaLorles Ŷ

Ind|cat|onť ModeraLe Lo severe palnŤ Ccular lLchlna assoclaLed wlLh seasonal alleralc con[uncLlvlLlsŤ
Þrophvlaxls and reducLlon of posLoperaLlve ocular lnflammaLlonŤ CvsLold macular oedemaŤ Þaln and
phoLophobla afLer lnclslonal refracLlve suraerv
Contra|nd|cat|onť PvpersenslLlvlLv Lo asplrln or oLher nSAlusţ asLhmaŦ Pvpovolaemla or dehvdraLlonŦ
uo noL alve posLoperaLlvelv Lo paLlenLs wlLh hlah rlsk of haemorrhaaeŦ PlsLorv of pepLlc ulcer or
coaaulaLlon dlsordersŦ nasal polvpsţ analoedemaţ bronchospasmŦ LabourŦ ModeraLe Lo severe renal
lmpalrmenLŦ Cl bleedlnaţ cerebrovascular bleedlnaŦ As prophvlacLlc analaeslc before suraervŦ
Þreanancvţ lacLaLlonŦ
Adverse effectsť Cl ulcerţ bleedlna and perforaLlonţ drowslnessţ rashţ bronchospasmţ hvpoLenslonţ
psvchoslsţ drv mouLhţ feverţ bradvcardlaţ chesL palnţ dlzzlnessţ headacheţ sweaLlnaţ oedemaţ pallorţ
llver funcLlon chanaesŦ 1ranslenL sLlnalna and local lrrlLaLlon (ophLhalmlc)Ŧ
Þotent|a||y Iata|ť AnaphvlaxlsŦ Severe skln reacLlonsŦ Mlţ sLrokeţ Cl bleedlnaŦ
Mechan|sm of act|onť keLorolac lnhlblLs prosLaalandln svnLhesls bv decreaslna Lhe acLlvlLv of Lhe
cvclooxvaenase enzvmeŦ











Nasathera Ŵ Þheny|propano|am|ne
Contentsť ÞaraceLamol 323 maţ phenvlpropanolamlne 23 maŦ paraceLamol 230 maţ Þer 3 mL svr
Þhenvlpropanolamlne PCl 12Ŧ3 ma Ŵ svsLemlc svmpaLhomlmeLlc preparaLlons used as nasal
deconaesLanLsŦ

Ind|cat|onť nasal conaesLlonţ headache Ǝ fever assoclaLed w/ slnuslLlsţ rhlnlLlsţ common cold Ǝ fluŦ
Adm|n|strat|onť Mav be Laken wlLh or wlLhouL food
Contra|nd|cat|onť PvperLhvroldlsmŤ P1nţ coronarv dlseaseŤ MAClsŤ nephropaLhvŤ benlan prosLaLlc
hvperLrophv Ǝ closedŴanale alaucomaŦ
Adverse keact|onsť Clddlnessţ headacheŤ Cl upseLsŤ sweaLlnaţ LhlrsLŤ Lachvcardlaţ precordlal palnţ
palplLaLlonsŤ dlfflculLv ln mlcLurlLlonŤ muscle weaknessŤ Lremorsţ anxleLvţ lnsomnlaŤ skln erupLlonsŦ




5|nupret
CLher uruas AcLlna on Lhe 8esplraLorv SvsLem

Ind|cat|onť AcuLe Ǝ chronlc lnflammaLlons of Lhe slnuses Ǝ Lhe resp LracLŤ supplemenLarv measure ln
anLlbacLerlal LherapvŦ
Adm|n|strat|onť Mav be Laken wlLh or wlLhouL food
5|de effectsť Pardlv everţ sLomach lnLoleranceŦ
ConLenLsť Lach draaee conLalns aenLlan rooL (CenLlanae radlx) 6 maţ prlmrose flower (prlmulae flos)
18 maţ common sorrel herb (8umlcus herba) 18 maţ elder flowers (Sambucl flos) 18 ma and shop
vervaln worL (verbenae herba) 18 maŦ





Þ|as|| Ŷ Metoc|opram|de
AnLlemeLlcsţ Cl1 8eaulaLorsţ AnLlflaLulenLs Ǝ AnLlŴlnflammaLorles Ŵ propulslvesŦ

Ind|cat|onsť ulsLurbances of Cl moLlllLv lncludlna CL8u Ǝ dlabeLlc aasLropareslsŦ nausea Ǝ vomlLlna
of cenLral Ǝ perlpheral orlaln assoclaLed w/ suraervţ meLabollc dlseasesţ lnfecLlous dlseasesţ mlaralne
headache or druas lncludlna cancer chemoLherapvŦ laclllLaLe small bowel lnLubaLlon Ǝ radloloalcal
procedures of Cl1Ŧ
Adm|n|strat|onť Should be Laken on an empLv sLomach (1ake 10 mlns before mealsŦ)Ŧ
Contra|nd|cat|onť Cl hemorrhaaeţ mechanlcal obsLrucLlon or perforaLlonţ pheochromocvLomaţ
epllepLlcsŦ
Adverse drug react|onsť 8esLlessnessţ drowslnessţ faLlaue Ǝ lasslLudeŦ LxLrapvramldal svmpLomsţ
lnsomnlaţ headacheţ dlzzlnessţ nauseaţ aalacLorrheaţ avnecomasLlaţ rash lncludlna urLlcarlaţ bowel
dlsLurbancesŦ lncreased prolacLln levelsŤ aasLropareslsŦ
Mechan|sm of act|onť MeLoclopramldeţ a dopamlne anLaaonlsLţ sLlmulaLes moLlllLv of Lhe upper
aasLrolnLesLlnal LracL wlLhouL sLlmulaLlna aasLrlcţ blllarv or pancreaLlc secreLlonsŦ lLs mode of acLlon ls
unclearŦ lL seems Lo senslLlze Llssues Lo Lhe acLlon of aceLvlchollneŦ 1he effecL of meLoclopramlde on
moLlllLv ls noL dependenL on lnLacL vaaal lnnervaLlon buL lL can be abollshed bv anLlchollneralc druasŦ
MeLoclopramlde lncreases Lhe Lone and ampllLude of aasLrlc (especlallv anLral) conLracLlonsţ relaxes
Lhe pvlorlc sphlncLer and Lhe duodenum and [e[unumţ resulLlna ln acceleraLed aasLrlc empLvlna and
lnLesLlnal LranslLŦ lL lncreases Lhe resLlna Lone of Lhe lower esophaaeal sphlncLerŦ














kanor
AnxlolvLlcs

Ind|cat|onť 1reaLmenL of panlc w/ or w/o aaoraphobla
Slde effecLť SedaLlonţ somnolenceţ memorv lmpalrmenLţ dvsarLhrlaţ abnormal coordlnaLlonţ aLaxlaţ
decreased llbldoŦ laLlaueţ depresslonŦ
Contra|nd|catedť AcuLe narrowŴanale alaucomaŦ keLoconazole Ǝ lLraconazoleŦ
Cons|derat|onť Mav be Laken wlLh or wlLhouL food (Slde effecLs such as sleeplness/ drowslness mav
be reduced lf Laken lmmedlaLelv afLer mealsŦ Swallow wholeţ do noL chew/crushŦ)
8lsk of dependenceţ w/drawal svmpLoms Ǝ selzuresŦ uevelopmenL of Loleranceţ emeraence of
anxleLv svmpLomsŦ Sulcldal ldeaLlon Ǝ manla ln severelv depressed paLlenLsŦ Mav affecL menLal
alerLness esp w/ alcohol or oLher CnS depressanLsŦ Þreanancv Ǝ lacLaLlonţ chlldn Ǝ elderlvŦ



Þ|racetam
nooLroplcs Ǝ neuroLonlcs

Ind|cat|onť Ad[uncL ln corLlcal mvoclonusţ As a coanlLlve enhancer ln cerebrocorLlcal lnsufflclencv
5|de effectsť Pvperklneslaţ nervousnessţ depresslonţ dlarrhoeaţ rashesŦ CnS sLlmulaLlonţ sleep
dlsLurbancesţ dlzzlnessţ exclLemenLţ lnsomnlaţ somnolenceţ wL aalnŦ
Mechan|sm of act|onť ÞlraceLam proLecLs Lhe cerebral corLex aaalnsL hvpoxlaŦ lL also lnhlblLs plaLeleL
aaareaaLlon and reduces blood vlscoslLvŦ
Contra|nd|cat|onť PepaLlc and severe renal lmpalrmenLŦ Cerebral haemorrhaaeŦ Þreanancv and
lacLaLlonŦ
Cons|derat|onsť Should be Laken wlLh foodŦ (1ake before mealsŦ)




Am|od|p|ne
Calclum AnLaaonlsLsţ AnLlŴAnalnal uruas

Ind|cat|onť PvperLenslonţ ÞrlnzmeLalƌs analnaţ SLable analna
Mechan|sm of act|onť Amlodlplne relaxes perlpheral and coronarv vascular smooLh muscleŦ lL
produces coronarv vasodllaLlon bv lnhlblLlna Lhe enLrv of Ca lons lnLo Lhe volLaaeŴsenslLlve channels
of Lhe vascular smooLh muscle and mvocardlum durlna depolarlsaLlonŦ lL also lncreases mvocardlal C2
dellverv ln paLlenLs wlLh vasospasLlc analnaŦ 8elonas Lo Lhe class of selecLlve dlhvdropvrldlne
derlvaLlve calclumŴchannel blockers wlLh malnlv vascular effecLsŦ used ln Lhe LreaLmenL of
cardlovascular dlseasesŦ
5|de effectť Peadacheţ perlpheral oedemaţ faLlaueţ somnolenceţ nauseaţ abdomlnal palnţ flushlnaţ
dvspepslaţ palplLaLlonsţ dlzzlnessŦ 8arelv prurlLusţ rashţ dvspnoeaţ asLhenlaţ muscle crampsŦ
ÞoLenLlallv laLalť PvpoLenslonţ bradvcardlaţ conducLlve svsLem delav and CClŦ Contra|nd|cat|onť
known hvpersenslLlvlLv Lo dlhvdropvrldlnesŦ Cons|derat|onť Mav be Laken wlLh or wlLhouL foodŦ

L|p|tor (Atorvastat|n Ca)
uvsllpldaemlc AaenLs

Ind|cat|onsť 8educLlon As an ad[uncL Lo dleL for Lhe reducLlon of elevaLed LoLal cholesLerolţ LuLŴ
cholesLerolţ apollpoproLeln 8 and Lrlalvcerldes and Lo lncrease PuLŴcholesLerol ln paLlenLs wlLh
prlmarv hvpercholesLerolemla (heLerozvaous famlllal and nonŴfamlllal hvpercholesLerolemla)ţ
comblned (mlxed) hvperllpldemla (lredrlckson 1vpes lla and llb)ţ elevaLed serum Lrlalvcerlde levels
(lredrlckson 1vpe lv) and for paLlenLs wlLh dvsbeLallpoproLelnemla (lredrlckson 1vpe lll) who do noL
respond adequaLelv Lo dleLŦ 8educLlon of LoLal cholesLerol and LuLŴcholesLerol ln paLlenLs wlLh
homozvaous famlllal hvpercholesLerolemla when response Lo dleL and oLher nonŴpharmacoloalcal
measures are lnadequaLeŦ Secondarv prevenLlon of Lhe comblned rlsk of deaLhţ nonfaLal Mlţ cardlac
arresL and reŴhosplLallzaLlon for analna pecLorls ln paLlenLs wlLh cardlovascular dlsease and/or
dvsllpldemlaŦ
Mechan|sm of act|onť ALorvasLaLln calclum ls a svnLheLlcţ selecLlve llpldŴlowerlna aaenLţ compeLlLlve
lnhlblLor of PMCŴCoA reducLaseţ Lhe raLeŴllmlLlna enzvme responslble for Lhe converslon of 3Ŵ
hvdroxvŴ3ŴmeLhvlŴaluLarvlŴcoŴenzvme A Lo mevalonaLeţ a precursor of sLerolsţ lncludlna cholesLerolŦ
ln paLlenLs wlLh homozvaous and heLerozvaous famlllal hvpercholesLerolemla (lP)ţ nonfamlllal forms
of hvpercholesLerolemla and mlxed dvsllpldemlaţ aLorvasLaLln reduces LoLal cholesLerol (LoLalŴC)ţ lowŴ
denslLv llpoproLeln cholesLerol (LuLŴC) and apollpoproLeln 8 (apo 8)Ŧ ALorvasLaLln also reduces verv
lowŴdenslLv llpoproLeln cholesLerol (vLuLŴC) and Lrlalvcerldes (1C) and produces varlable lncreases ln
hlahŴdenslLv llpoproLeln cholesLerol (PuLŴC)Ŧ
ALorvasLaLln lowers plasma cholesLerol and llpoproLeln levels bv lnhlblLlna PMCŴCoA
reducLase and cholesLerol svnLhesls ln Lhe llver and bv lncreaslna Lhe number of hepaLlc LuL
recepLors on Lhe cell surface for enhanced upLake and caLabollsm of LuLŦ
ALorvasLaLln reduces LuL producLlon and Lhe number of LuL parLlclesŦ lL produces a
profound and susLalned lncrease ln LuL recepLor acLlvlLv coupled wlLh a beneflclal chanae ln Lhe
quallLv of clrculaLlna LuL parLlclesŦ ALorvasLaLln ls effecLlve ln reduclna LuL ln paLlenLs wlLh
homozvaous famlllal hvpercholesLerolemlaţ a populaLlon LhaL has noL normallv responded Lo llpldŴ
lowerlna medlcaLlonŦ
5|de effectsť nauseaţ dlarrheaţ dvspepsla Ǝ flaLulenceţ mvalalaŦ Pvpoalvcemlaţ hvperalvcemlaţ
anorexlaŦ 1hrombocvLopenlaţ Lendon rupLureţ wL aalnţ hvpoesLheslaţ amneslaţ dlzzlnessţ dvsaueslaţ
SLevensŴ!ohnson svndromeţ Loxlc epldermal necrolvslsţ ervLhema mulLlformeţ bullous rashesţ
urLlcarlaţ rhabdomvolvslsţ back Ǝ chesL palnţ perlpheral edemaţ malalse Ǝ faLlaueŦ CholesLaslsţ paln
ln exLremlLvţ musculoskeleLal palnţ muscle spasmţ [olnL swelllnaţ nlahLmaresţ blurred vlslonţ hepaLlLlsţ
muscle faLlaueţ neck palnţ pvrexlaţ nasopharvnalLlsţ pharvnaolarenaeal palnţ eplsLaxlsŦ
Contra|nd|cat|onsť Þreanancv Ǝ lacLaLlonŦ ÞaLlenLs who have hvpersenslLlvlLv Lo anv of Lhe
componenLs of LlplLor or who have acLlve llver dlsease or unexplalned perslsLenL elevaLlons of serum
Lransamlnases exceedlna 3 Llmes Lhe upper llmlL of normalŦ
Cons|derat|onsť Mav be Laken wlLh or wlLhouL food
MonlLor for creaLlne phosphoklnase Ǝ Lransamlnase elevaLlonsŦ Avold alcohol consumpLlonŦ
1emporarllv dlsconLlnue Lherapv ln paLlenL w/ an acuLeţ serlous condlLlon suaaesLlve of a
mvopaLhv of renal fallure secondarv Lo rhabdomvolvslsŦ




C||ostazo|
AnLlcoaaulanLsţ AnLlplaLeleLs Ǝ llbrlnolvLlcs (1hrombolvLlcs)

Ind|cat|onť Þerlpheral vascular dlsease
Mechan|sm of act|onť CllosLazol ls a reverslbleţ selecLlve lnhlblLor of phosphodlesLeraseŴlll (ÞuLŴlll)ţ
Lherebv suppresslna cvcllc adenoslne monophosphaLe (cAMÞ) dearadaLlonŦ lncrease ln cAMÞ ln
plaLeleLs and blood vessels leads Lo lnhlblLlon of plaLeleL aaareaaLlon and vasodllaLlonŦ CllosLazol also
lnhlblLs adenoslne upLake lnLo cellsţ whlch auamenLs Lhe cAMÞŴelevaLlna effecL of ÞuLŴlll lnhlblLlonŦ
5|de effectsť Peadacheţ dlzzlnessţ palplLaLlonsţ dlarrhoeaţ abnormal sLoolsŤ palnţ lnfecLlonŤ perlpheral
oedemaţ nauseaţ vomlLlnaţ oLher cardlac arrhvLhmlasţ chesL palnţ rhlnlLlsţ pharvnalLlsţ ecchvmosls
and skln rashŦ
Contra|nd|cat|onť PearL fallureŤ known predlsposlLlon Lo bleedlnaŤ hlsLorv of venLrlcular arrhvLhmlasŤ
C1 lnLerval prolonaaLlonŤ severe renal lmpalrmenLŤ moderaLe Lo severe hepaLlc lmpalrmenLŦ
Cons|derat|onť Should be Laken on an empLv sLomachŦ (1ake aL leasL Z hr before or 2 hr afLer mealsŦ)

ketoster||
keLoanaloaues Ǝ essenLlal amlno aclds

Ind|cat|onsť ÞrevenLlon and Lherapv of damaaes due Lo faulLv or deflclenL proLeln meLabollsm ln
chronlc renal lnsufflclencv ln connecLlon wlLh llmlLed proLeln ln food of 40 a/dav (for adulLs) and lessŤ
leţ aenerallv ln paLlenLs wlLh a alomerular fllLraLlon raLe (Cl8) Ƽ 23 mL/mlnŦ
5|de effectsť PvpercalcemlaŦ MonlLor reaularlv Lhe serum calclum levelŦ Lnsure Lhe sufflclenL supplv
wlLh calorlesŦ
Adverse effectť PvpercalcemlaŦ
Cons|derat|onť Should be Laken wlLh food (Swallow wholeţ do noL chew/crushŦ)Ŧ
Contra|nd|cat|onť Pvpercalcemlaţ dlsLurbed amlno acld meLabollsmŦ




Ar|xtra Ŵ Iondapar|nux Na
AnLlcoaaulanLsţ AnLlplaLeleLs Ǝ llbrlnolvLlcs (1hrombolvLlcs)

Ind|cat|onsť ÞrevenLlon of venous Lhromboembollc evenLs (v1L) ln paLlenLs underaolna ma[or
orLhopedlc suraerv of Lhe lower llmbsŦ ÞaLlenLs underaolna abdomlnal suraerv who are aL rlsk of
Lhromboembollc compllcaLlonsŤ ln paLlenLs who are aL rlsk of Lhromboembollc compllcaLlons due Lo
resLrlcLed moblllLv durlna acuLe lllnessŦ 1reaLmenL of acuLe deep veln Lhrombosls (uv1)ţ pulmonarv
embollsm (ÞL)ţ unsLable analna or nonŴS1 seamenL elevaLlon Ml (uA/nS1LMl) acuLe coronarv
svndrome for Lhe prevenLlon of deaLhţ Ml Ǝ refracLorv lschemlaŦ 1reaLmenL of S1 seamenL elevaLlon
Ml (S1LMl) acuLe coronarv svndrome for Lhe prevenLlon of deaLh Ǝ Ml ln paLlenLs who are manaaed
w/ LhrombolvLlcs or who lnlLlallv are Lo recelve no oLher form of reperfuslon LherapvŦ
Mechan|sm of Act|onť londaparlnux ls a svnLheLlc and selecLlve lnhlblLor of acLlvaLed lacLor x (xa)Ŧ
1he anLlLhromboLlc acLlvlLv of fondaparlnux ls Lhe resulL of anLlLhrombln lll (A1lll)ŴmedlaLed selecLlve
lnhlblLlon of lacLor xaŦ 8v blndlna selecLlvelv Lo A1lllţ fondaparlnux poLenLlaLes (abouL 300 Llmes) Lhe
lnnaLe neuLrallzaLlon of lacLor xa bv A1lllŦ neuLrallzaLlon of lacLor xa lnLerrupLs Lhe blood
coaaulaLlon cascade and lnhlblLs boLh Lhrombln formaLlon and Lhrombus developmenLŦ londaparlnux
does noL lnacLlvaLe Lhrombln (acLlvaLed lacLor ll) and has no known effecL on plaLeleL funcLlonŦ
Contra|nd|cat|onť known hvpersenslLlvlLv Lo fondaparlnux sodlum or anv of Lhe exclplenLs of ArlxLraŦ
AcLlve cllnlcallv slanlflcanL bleedlnaŦ AcuLe bacLerlal endocardlLlsŦ
Adverse react|onsť Anemlaţ bleedlnaţ purpuraţ edemaŦ











Asp||ets Ŵ Acety|sa||cy||c ac|d
AnLlcoaaulanLsţ AnLlplaLeleLs Ǝ llbrlnolvLlcs (1hrombolvLlcs) Ŵ 8elonas Lo Lhe class of plaLeleL
aaareaaLlon lnhlblLors excludlna heparlnŦ used ln Lhe LreaLmenL of Lhrombosls

Ind|cat|onsť ¾pllet SuspecLed acuLe MlŤ ¾pllet/£c ÞrophvlacLlc LreaLmenL of Lhromboembollc
dlsordersţ Mlţ LranslenL lschemlc aLLacks Ǝ sLrokeŦ lor Lhe secondarv prevenLlon of Cv dlsease ln uM
paLlenLs esp Lhose w/ hlsLorv of Mlţ vascular bvpass procedureţ sLroke or LranslenL lschemlc aLLack Ǝ
analna Ǝ Lhose w/ addlLlonal rlsk facLorsť P1nţ smoklnaţ dvsllpldemla Ǝ famllv hlsLorv of Cv dlseaseŦ
8evascularlzaLlon proceduresŦ ÞreanancvŴlnduced P1nŦ
Adverse react|onsť leverţ hvpoLhermlaţ LhlrsLŦ uvsrvLhmlasţ hvpoLenslonţ LachvcardlaŦ AalLaLlonţ
cerebral edemaţ comaţ confuslonţ dlzzlnessţ headacheţ subdural or lnLracranlal hemorrhaaeţ leLharavţ
selzuresŦ uehvdraLlonţ hvperkalemlaţ meLabollc acldoslsţ resp alkaloslsţ dvspepslaţ Cl bleedlnaţ
ulceraLlon Ǝ perforaLlonţ nauseaţ vomlLlnaţ LranslenL hepaLlc enzvme elevaLlonsţ hepaLlLlsţ 8eveƌs
svndromeţ pancreaLlLlsŦ ÞrolonaaLlon of proLhrombln Llmeţ dlssemlnaLed lnLravascular coaaulaLlonţ
coaaulopaLhvţ LhrombocvLopenlaŦ AcuLe anaphvlaxlsţ analoedemaţ asLhmaţ bronchospasmţ larvnaeal
edemaţ urLlcarlaŦ Pearlna lossţ LlnnlLusŦ Þrolonaed preanancv Ǝ laborţ sLlllblrLhsţ low blrLh wL lnfanLsţ
anLeparLum Ǝ posLparLum bleedlnaŦ Pvperpneaţ pulmonarv edemaţ LachvpneaŦ lnLersLlLlal nephrlLlsţ
paplllarv necroslsţ proLelnurlaţ renal lnsufflclencv Ǝ fallureŦ 8habdomvolvslsŦ Pvpo/hvperalvcemlaŦ
Contra|nd|cat|onsť AsLhmaţ rhlnlLls Ǝ nasal polvpsŦ PlsLorv of acLlve pepLlc ulcer dlseaseŦ
PvpersenslLlvlLvŦ
Cons|derat|onsť Should be Laken wlLh food (1ake lmmedlaLelv afLer meals w/ a full alass of waLer
unless paLlenL ls fluldŴresLrlcLedŦ Swallow wholeţ do noL chew/ crush/ blLe Lhe LabŦ)Ŧ








Am|od|p|ne
AnLlŴAnalnal uruas / Calclum AnLaaonlsLs

Ind|cat|onsť PvperLenslonţ ÞrlnzmeLalƌs analnaţ SLable analna
Mechan|sm of act|onť Amlodlplne relaxes perlpheral and coronarv vascular smooLh muscleŦ lL
produces coronarv vasodllaLlon bv lnhlblLlna Lhe enLrv of Ca lons lnLo Lhe volLaaeŴsenslLlve channels
of Lhe vascular smooLh muscle and mvocardlum durlna depolarlsaLlonŦ lL also lncreases mvocardlal C2
dellverv ln paLlenLs wlLh vasospasLlc analnaŦ
Adverse keact|onsť Peadacheţ perlpheral oedemaţ faLlaueţ somnolenceţ nauseaţ abdomlnal palnţ
flushlnaţ dvspepslaţ palplLaLlonsţ dlzzlnessŦ 8arelv prurlLusţ rashţ dvspnoeaţ asLhenlaţ muscle crampsŦ
O Þotent|a||y Iata|ť PvpoLenslonţ bradvcardlaţ conducLlve svsLem delav and CClŦ
Cons|derat|onsť Mav be Laken wlLh or wlLhouL foodŦ
Contra|nd|cat|onsť known hvpersenslLlvlLv Lo dlhvdropvrldlnesŦ


Ca|trate Þ|us
Calclum/wlLh vlLamlns / vlLamlns Ǝ Mlnerals (Þre Ǝ ÞosL naLal) / AnLlanemlcs Ŵ 8elonas Lo Lhe class
of calclumŴconLalnlna preparaLlonsŦ used as dleLarv supplemenLsŦ

Ind|cat|onsť SupplemenL for Ca deflclencv Ǝ condlLlons LhaL requlre lncreased Ca lnLakeŤ mav reduce
Lhe rlsk of osLeoporosls laLer ln llfeŦ
Contentsť Ca 600 maţ vlL u 200 luţ copper 1 maţ Ma 30 maţ manaanese 1Ŧ8 maţ Zn 7Ŧ3 ma
Cons|derat|onsť Should be Laken wlLh food







Depon|t
AnLlŴAnalnal uruas

Ind|cat|onsť LonaŴLerm LreaLmenL of coronarv hearL dlseaseţ LreaLmenL and prevenLlon of analna
pecLorls (even afLer sufflclenLlv LreaLed mvocardlal lnfacrLlon)ţ LreaLmenL of severe chronlc
mvocardlal lnsufflclencv ln comblnaLlon wlLh cardlac alvcosldesţ dlureLlcsţ ACL lnhlblLors or arLerlal
vasodllaLorsŦ Þulmonarv hvperLenslonŦ
Mechan|sm of act|onť Llke all oraanlc nlLraLesţ nlLroalvcerln acLs as a donor of nlLrlc oxlde (nC)Ŧ nlLrlc
oxlde causes relaxaLlon of vascular smooLh muscle vla Lhe sLlmulaLlon of auanvlvl cvclase and Lhe
subsequenL lncrease of lnLracellular cvcllc auanoslne monophosphaLe (cCMÞ) concenLraLlonŦ A
cCMÞŴdependenL proLeln klnase ls Lhus sLlmulaLedţ wlLh resulLanL of Lhe phosphorvlaLlon of varlous
proLelns ln smooLh muscle cellŦ 1hls evenLuallv leads Lo Lhe dephosphorvlaLlon of Lhe llahL chaln of
mvosln and Lhe lowerlna of conLracLlllLvŦ
Adverse react|onsť 1ranslenL headacheţ reflex Lachvcardlaţ posLural hvpoLenslonţ nauseaţ dlzzlnessţ
alleravŦ
Contra|nd|cat|onsť Hypersensitivity to nitroglycerin, other nitrate compounds or to any oI the
excipients oI Deponit NT.
cute circulatory Iailure (shock, collapse), cardiogenic shock (unless a suIIicient end-diastolic
pressure is maintained by appropriate measures), hypertropic obstructive cardiomyopathy,
constrictive pericarditis, cardiac tamponade, severe hypotension (systolic blood pressure ·90 mm
Hg). During nitrate therapy, phosphodiesterase inhibitors ( eg, sildenaIil) must not be used
Cons|derat|onsť ueponlL n1 ls usuallv sLarLed wlLh 1 Lransdermal paLch dallvŦ lf necessarvţ Lhe dose
mav be lncreased for Lhe doses of 3 and 10 ma (2 paLches slmulLaneouslv)Ŧ 1here ls no evldence Lo
suaaesL an ad[usLmenL of Lhe dosaae ln elderlv paLlenLsŦ 1he safeLv and efflcacv has veL Lo be
esLabllshed ln chlldrenŦ
ueponlL n1 mav affecL Lhe paLlenLƌs reacLlvlLv Lo an exLenL LhaL Lhe ablllLv Lo drlve or Lo operaLe
machlnerv ls lmpalredŦ 1hls effecL ls lncreased ln comblnaLlon wlLh alcoholŦ
ueponlL n1 ls noL sulLable for LreaLmenL of acuLe analna aLLacksŦ
1he paLch should be applled Lo healLhvţ undamaaed and relaLlvelv creaseŴfree and halrless sklnŦ
Skln care producLs should noL be used before applvlna Lhe paLchŦ
1he same slLe should noL be used aaaln before some davs have passedŦ 1o avold developmenL
of Loleranceţ Lhe paLch should remaln on Lhe skln onlv for abouL 12Ŵ16 hrsţ Lo ensure a nlLraLeŴ
free lnLerval of 18Ŵ12 hrsŦ An addlLlonal anLl analna Lherapv wlLh druas noL conLalnlna nlLro
compounds should be consldered for Lhe nlLraLeŴfree perlodŦ lor Lhe purpose of lndlvldual
doslna for each paLlenLţ Lhe nlLroalvcerln paLch can be cuL lnLo smaller plecesŦ 1he pleces
adhere [usL as well as fullŴslze svsLemsŦ 1he dose ls deLermlned bv Lhe surface area of Lhe plece
relaLlve Lo LhaL of Lhe orlalnal svsLemŦ







Cefurox|me Ŷ 2egen
Cephalosporlns

Ind|cat|onsť uncompllcaLed urlnarv LracL lnfecLlonsţ 8esplraLorv LracL lnfecLlonsţ uncompllcaLed
aonorrhoeaţ CLlLls medlaţ MenlnalLlsţ Þrophvlaxls of suralcal lnfecLlonsţ SuscepLlble lnfecLlons
Mechan|sm of act|onť Cefuroxlme blnds Lo one or more of Lhe penlcllllnŴblndlna proLelns (Þ8Þs)
whlch lnhlblLs Lhe flnal LranspepLldaLlon sLep of pepLldoalvcan svnLhesls ln bacLerlal cell wallţ Lhus
lnhlblLlna blosvnLhesls and arresLlna cell wall assemblv resulLlna ln bacLerlal cell deaLhŦ
Adverse react|onsť Larae doses can cause cerebral lrrlLaLlon and convulslonsŤ nauseaţ vomlLlnaţ
dlarrhoeaţ Cl dlsLurbancesŤ ervLhema mulLlformeţ SLevensŴ!ohnson svndromeţ epldermal necrolvslsŦ
ÞoLenLlallv laLalť Anaphvlaxlsţ nephroLoxlclLvţ pseudomembranous collLlsŦ
Contra|nd|cat|onsť PvpersenslLlvlLv Lo cephalosporlnsŦ
Cons|derat|onsťShould be Laken wlLh foodŦ
Þotent|a||y Iata|ť nephroLoxlclLv wlLh amlnoalvcosldes and furosemldeŦ

Metropo|o|
8eLaŴ8lockers / AnLlmlaralne ÞreparaLlons

Ind|cat|onsť ÞC P1nţ Analna pecLorlsţ Cardlac arrhvLhmlasţ Ad[uncL ln hvperLhvroldlsmţ Mlaralne
prophvlaxlsţ Ad[uncL ln Lhe earlv manaaemenL of acuLe Mlţ SLable svmpLomaLlc hearL fallureţ
Lmeraencv LreaLmenL of cardlac arrhvLhmlasţ ÞrevenLlon or conLrol of arrhvLhmlas on lnducLlon of
anesLheslaţ
Mechan|sm of act|onť MeLoprolol selecLlvelv lnhlblLs ĒŴadreneralc recepLors buL has llLLle or no effecL
on Ē2ŴrecepLors excepL ln hlah dosesŦ lL has no membraneŴsLablllslna nor lnLrlnslc svmpaLhomlmeLlc
acLlvlLvŦ 8elonas Lo Lhe class of selecLlve beLaŴblocklna aaenLsŦ used ln Lhe LreaLmenL of
cardlovascular dlseasesŦ
Adverse react|onť 8radvcardlaţ hvpoLenslonţ arLerlal lnsufflclencvţ chesL palnţ CPlţ oedemaţ
palplLaLlonţ svncopeţ aanareneŤ dlzzlnessţ faLlaueţ depresslonţ confuslonţ headacheţ lnsomnlaţ shorLŴ
Lerm memorv lossţ nlahLmaresţ somnolenceŤ prurlLusţ rashţ lncreased psorlaslsţ reverslble alopeclaŤ
sexual dvsfuncLlon/lmpoLenceţ Þevronleƌs dlseaseŤ dlarrhoeaţ consLlpaLlonţ flaLulenceţ Cl palnţ
hearLburnţ nauseaţ xerosLomlaŤ aaranulocvLosls (rare)Ť musculoskeleLal palnŤ blurred vlslonţ drv evesţ
oculomucocuLaneous svndromeŤ LlnnlLusŤ dvspnoeaţ bronchospasmţ wheezlnaţ rhlnlLlsŤ cold
exLremlLlesŦ
ÞoLenLlallv laLalť PearL fallureţ hearL blockţ bronchospasmŦ
Contra|nd|cat|onť 2nd or 3rd dearee Av blockŤ slck slnus svndromeŤ decompensaLed hearL fallureŤ
cllnlcallv relevanL slnus bradvcardlaŦ Severe perlpheral arLerlal clrculaLorv dlsordersŦ Cardloaenlc
shockŦ AsLhmaŦ ÞhaeochromocvLoma (wlLhouL ĐŴblockade)ţ svsLollc 8Þ Ƽ100 mmPaŦ MeLabollc
acldoslsŦ Þreanancv (2nd and 3rd LrlmesLers)Ŧ
Cons|derat|onsťMav be Laken wlLh or wlLhouL foodŦ






CoŴD|ovan
AnaloLensln ll AnLaaonlsLs / ulureLlcs

Contentsť Þer 80/12Ŧ3 ma Lab valsarLan 80 maţ hvdrochloroLhlazlde 12Ŧ3 maŦ Þer 160/12Ŧ3 ma Lab
valsarLan 160 maţ hvdrochloroLhlazlde 12Ŧ3 maŦ Þer 160/23 ma Lab valsarLan 160 maţ
hvdrochloroLhlazlde 23 maŦ Þer 320/12Ŧ3 ma Lab valsarLan 320 maţ hvdrochloroLhlazlde 12Ŧ3 maŦ Þer
320/23 ma Lab valsarLan 320 maţ hvdrochloroLhlazlde 23 ma
Ind|cat|onsť P1n
Mechan|sm of act|onť ACL lnhlblLors produce vasodllaLlon bv lnhlblLlna Lhe formaLlon of analoLensln
llŦ 1hls vasoconsLrlcLor ls formed bv Lhe proLeolvLlc acLlon of renln (released bv Lhe kldnevs) acLlna on
clrculaLlna analoLenslnoaen Lo form analoLensln lŦ AnaloLensln l ls Lhen converLed Lo analoLensln ll bv
analoLensln converLlna enzvmeŦ
ACL also breaks down bradvklnln (a vasodllaLor subsLance)Ŧ 1hereforeţ ACL lnhlblLorsţ bv blocklna Lhe
breakdown of bradvklnlnţ lncrease bradvklnln levelsţ whlch can conLrlbuLe Lo Lhe vasodllaLor acLlon of
ACL lnhlblLorsŦ 1he lncrease ln bradvklnln ls also belleved Lo be responslble for a Lroublesome slde
effecL of ACL lnhlblLorsţ namelvţ a drv couahŦ
AnaloLensln ll consLrlcLs arLerles and velns bv blndlna Lo A11 recepLors locaLed on Lhe smooLh muscleţ
whlch are coupled Lo a CqŴproLeln and Lhe Lhe lÞ3 slanal LransducLlon paLhwavŦ AnaloLensln ll also
faclllLaLes Lhe release of noreplnephrlne from svmpaLheLlc adreneralc nerves and lnhlblLs
noreplnephrlne reupLake bv Lhese nervesŦ 1hls effecL of analoLensln ll auamenLs svmpaLheLlc acLlvlLv
on Lhe hearL and blood vesselsŦ
Adverse react|onsť Peadacheţ dlzzlnessţ faLlaueŦ PvdrochloroLhlazldeť Pvpokalemlaţ hvperurlcemlaţ
elecLrolvLe dlsLurbancesţ posLural hvpoLenslonţ rlse ln blood llpldsŦ 8arelvţ [aundlceţ cardlac
arrhvLhmlasţ blood dvscraslasŦ verv rarelvţ vascullLlsţ pancreaLlLlsţ pneumonlLlsţ pulmonarv edemaţ
hvpersenslLlvlLv reacLlons ea analoedemaţ lmpalred renal funcLlonţ mvalala Ǝ LhrombocvLopenlaŦ
neuLropenlaţ devlaLlons ln creaLlnlne Ǝ 8unŦ
Contra|nd|cat|onsť Þreanancv Ǝ severe hepaLlc lmpalrmenLţ blllarv clrrhosls Ǝ cholesLaslsŦ Anurlaţ
severe renal lmpalrmenL (CrCl Ƽ30 mL/mln)Ŧ 8efracLorv hvpokalemlaţ hvponaLremlaţ hvpercalcemla Ǝ
svmpLomaLlc hvperurlcemlaŦ
Cons|derat|onsť Mav be Laken wlLh or wlLhouL food


5od|um 8|carbonate
AnLacld Ŵ neuLrallzes sLomach acld

Ind|cat|onť Sodlum blcarbonaLe ls used Lo relleve hearLburn and lndlaesLlonŦ Sodlum blcarbonaLe ls
also used Lo make Lhe blood and urlne less acldlc ln cerLaln condlLlons
ulabeLlc keLoacldoslsţ MeLabollc Acldoslsţ urlnarv AlkallnlzaLlonţ uvspepslaţ Pvperkalemlaţ AsvsLoleţ
Pvperurlcemla Secondarv Lo ChemoLherapv
Mechan|sm of act|onť ClrculaLorv overload and hvpernaLremla can occur when larae volumes of
hvperLonlc sodlum blcarbonaLe are alvenŦ lf hvpocalcemla ls presenLţ selzures and LeLanv mav occur
as blood pP rlses and Lhe lonlzed free calclum decreasesŤ henceţ calclum should be alven flrsLŦ
PvponaLremla wlll maanlfv Lhe cardlac effecLs of hvperkalemlaţ and sodlum blcarbonaLe can be used
Lo LreaL Lhls as wellŦ
Adverse react|onť SLop Laklna sodlum blcarbonaLe and seek emeraencv medlcal aLLenLlon lf vou
experlence a rare alleralc reacLlon (dlfflculLv breaLhlnaŤ closlna of Lhe LhroaLŤ swelllna of Lhe llpsţ
Lonaueţ or faceŤ or hlves)Ŧ nausea or vomlLlnaŤ headacheŤ sever mood chanaesŤ muscle palnŤ swelllna
of feeLţ ankles or leas decreased appeLlLeŤ unusual LlrednessŤ consLlpaLlonŤ drv mouLh or lncreased
LhlrsLŤ or lncreased urlnaLlonŦ
Contra|nd|cat|onť an lnLesLlnal problem or appendlclLlsŤ hearL problemsŤ hlah blood pressureŤ
swelllna of Lhe arms or leasŤ kldnev dlseaseŤ llver dlseaseŤ or problems urlnaLlna












1rlmeLazldlne
AnLlŴAnalnal uruas

Ind|cat|onť Analna pecLorlsţ Menlereƌs dlsease
Mechan|sm of act|onť 1rlmeLazldlne ls a cellular acLlna anLlŴlschaemlc aaenLŦ lL has 3 maln properLles
bv whlch lL acLs as a cvLoproLecLlve aaenLŦ lL lnhlblLs Lhe anaeroblc alvcolvsls and faLLv acld
meLabollsmţ Lhus allowlna onlv aeroblc alvcolvslsŦ 1hls acLlon helps Lo resLore Lhe enerav balance ln
Lhe cellŦ lL lnhlblLs acldosls and free radlcal accumulaLlon ln Lhe cellŦ All Lhese acLlon help Lhe cell Lo
resLore Lhe normal lonlc and meLabollc balanceŦ
Adverse react|onť Cl dlsLurbancesţ vomlLlnaţ nauseaŦ
Should be Laken wlLh foodŦ
Contra|nd|cat|onť PvpersenslLlvlLvŦ Þreanancv and lacLaLlonŦ


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