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Risk Factors

Change in the condition of the plaque in the coronary artery Activation of Platelets Formation of thrombus Ischemia of tissue in the region supplied by the artery Coronary blood supply less than demand

Aspirin Antiplate let aggregat es

Thrombolyti c Therapy Glycoprotei n IIB/IIIA receptor antagonist

ECG CT-Scan, MRI Elevate d ST segmen tQ wave appears Lab. Test

Nitrat es

Altered repolarization of the myocardium

Beta -Block ers

Release of lysosomal enzyme Anaerobic Glycolysis Myocardial irritability Lactic Acid Production

Elevated CK-MB, Elevated myoglobi n, Troponin T,Toponi nI

Myocardial cell death


Oxyge n

Decreased contractility

Angi na
Dysrhyt mias

Stimulation of the sympathetic nervous system

Antidysrhyt hmias

Ventricular Remodeling Heart Failure Increa sed heart rate Increased Oxygen needs Increase afterload Nitrat es

Decreased left ventricular function

Angiotens in convertin g enzyme inhibitors


Increase preload

Decreased cardiac output

Cardiogenic Shock Ndx: Decreased Cardiac output related to negative inotopic changes in the heart secondary to myocardial ischemia

Fluid Restricti on

Increa sed CVP Increa sed PCWP

Decre ased LV ejectio n fractio n

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Treatment Clinical Manifestations Exam Nursing Diagnosis