DRUG STUDY

Generic Name Amikacin sulfate Brand Name: Amikin ACTION INDICATIONS CONTRAINDICATI ONS • Contraindicated in patients hypersensitive to drug or other aminogycosides. • Use cautiously in patients with impaired renal function or neuromuscular disorders, in neonates and infants and in elderly patients. ADVERSE EFFECTS NS: -neuromuscular blockade EENT: -ototoxicity NURSING RESPONSIBILITIES • Obtain specimen for culture and sensitivity test before giving first dose. Therapy may begin while awaiting the results. • Evaluate patient’s hearing before and during therapy if he will be receiving drug for longer than 2 weeks. Notify prescriber if patient has tinnitus, vertigo, or hearing loss. • Weigh patient and review renal function studies before therapy begins. • Correct dehydration before therapy because of increase risk of toxicity. • Obtain blood for

Inhibits protein synthesis by binding directly to the 30S ribosomal sub unit; bactericidal Classification: Amino glycoside

• Serious infection cause by sensitive restrains of Pseudomonas aeruginusa, E.coli, Proteus, Klebsiella, staphylococcus • Uncomplicated UTI caused by organism susceptible to less toxic drugs. • Active tuberculosis, with other antituberculotics • Mycobacterium avium complex (MAC) infection.

chills. to 1 hour after IV infusion ends. such as continued fever. for trough levels draw blood just before the next dose.M injection and 30 mins. • Peak drug levels more than 35 mcg/ml and trough levels more than 10 mcg/ml may linked to a higher risk of toxicity • Watch for signs and symptoms of super infection (especially URT). and increased pulse rate. Don’t collect blood in a heparinized tube.peak level 1 hour I. heparin is incompatible with aminoglycosides. .

particularly to drugs. burning. thus reducing the production of It is effective for the treatment of penicillinaseproducing Neisseria gonorrhoea (PPNG). positive Coombs' NURSING RESPONSIBILITIES Inhibits the enzyme responsible for the conversion of purines to uric acid. and history of allergies. lactation ADVERSE EFFECTS Body as a Whole: Thrombophlebitis (IV site). • . superinfections. cellulitis (IM site). pregnancy (category B). pain. Effectively treats Determine history of hypersensitivity reactions to cephalosporins. penicillins.Generic Name Cefuroxim e ACTION INDICATIONS CONTRAINDICATI ONS Hypersensitivity to cephalosporins and related antibiotics.

ANTIBIOTIC. Urogenital: Increased serum creatinine and BUN. Although pseudomembranous colitis. reducing or eliminating infection. pharyngitis/tonsill itis. Generic Name Albuterol Sulfate Salbutamo l Neb ACTION INDICATIONS CONTRAINDICA TIONS • Contraindicated with hypersensitivity to albuterol. bronchitis. • Inspect IM and IV injection sites frequently for signs of phlebitis. CNS stimulation. pruritus. sinusitis.insomnia.a pprehension. otitis media. decreased creatinine clearance.uric acid with a decrease in serum and sometimes in urinary uric acid levels.hyperkin esia. test. ADVERSE EFFECTS CNS:Restlessness. skin and soft tissue infections. before therapy is initiated. antibioticassociated colitis. • Report onset of loose stools or diarrhea. Skin: Rash. gonorrhea. lower respiratory tract infections. anxiety. urinary tract infections. nausea. and is used for surgical prophylaxis. urticaria. • Use minimal In low doses. acts relatively selectively at beta 2 – • Relief and prevention of brochospasm in patients with . relieving the signs and symptoms of gout CLASSIFICATIO N ANTIINFECTIVE. meningitis. GI: Diarrhea. • Monitor I&O rates and pattern: Especially important in severely ill patients receiving high doses. Report any significant changes. fear.tremo NURSING RESPONSIBILITIES • Observe 10 rights in giving medications. SECONDGENERATION CEPHALOSPORIN bone and joint infections.

tachycardia irritability. tachyarrhythmias r. administer pressurized inhalation drug forms during second half of inspiration. bronchospasm. drug tolerance can occur with prolonged used. should be use with respiratory distress ) on standby in case cardiac arrhythmias occur • Do not exceed the recommended dosage. flushing GI:Nausea. because the airways are open wider and the aerosol distribution is more extensive. beta 2 selectivity is lost. headache intoxication. hyperthyroidism.adrenergic receptors to cause bronchodilation and vasodilation. with diabetes palpitations. • Use cautiously tachycardia. PVCs mellitus. . pulmonary edema. C V: Cardiac arrhythmias. unusual or bad taste GU: Increased incidence of leiomyomas of uterus when given in higher than human doses in preclinical studies Respiratory: Respiratory difficulties. paradoxical airway resistance with repeated.weakness cause by digitalis . excessive use of inhalation preparations doses for minimal periods. at higher doses. anginal pain history of seizure Dermatologic: disorders. vertigo. heartburn.drowsiness. (rare). • Inhalation: treatment of acute attacks of brochospasm. coughing. • Maintain a – adrenergic blocker ( cardioselective beta – blocker. . • Prevention of exercise-induced brochospasm. Sweating. vomiting. such as atenolol. seems to lower potassium concentration when inhaled by patients on hemodialysis. and the drug acts at beta 2 receptors to cause typical sympathomimeti c cardiac effect. pallor. Drug Classification: Sympathomimeti c drug Beta2-selective adrenergic agonist Bronchodilator Antiasthmatic reversible obstructive airway disease. • Unlabeled use: adjunct in treating serious hyperkalemia in dialysis patients.

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