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Kemstro (baclofen)

Kemstro (baclofen)

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Published by: E on Oct 08, 2008
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Clinical Medications Worksheets

Generic Name baclofen Peak Unknown Trade Name Kemstro, Lioresal Onset Hrs-wks Classification antispasticity agents Dose 40mg Route PO Time/frequency 6 hr Duration Unknown Normal dosage range 5 mg 3 times daily. May increase q 3 days by 5 mg/dose up to 80 mg/day (some patients may have a better response to 4 divided doses) For IV meds, compatibility with IV drips and/or solutions N/A Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity

Why is your patient getting this medication Treatment of reversible spasticity due to multiple sclerosis or spinal cord lesions Mechanism of action and indications (Why med ordered) Inhibits reflexes at the spinal level. Decreased muscle spasticity; bowel and bladder function may also be improved.

Common side effects Dizziness, drowsiness, fatigue, weakness, nausea Interactions with other patient drugs, OTC or herbal Lab value alterations caused by medicine medicines (ask patient specifically) May cause ↑ in serum glucose, alkaline phosphatase, AST, and ALT Morphine: Central nervous system- and/or respiratorylevels depressant effects may be additively or synergistically Be sure to teach the patient the following about this medication increased in patients taking multiple drugs that cause these Instruct patient to take baclofen as directed. Take a missed dose within effects, especially in elderly or debilitated patients. 1 hr; do not double doses. Caution patient to avoid abrupt withdrawal Lorazepam: Central nervous system- and/or respiratoryof this medication because it may precipitate an acute withdrawal depressant effects may be additively or synergistically reaction (hallucinations, increased spasticity, seizures, mental changes, increased in patients taking multiple drugs that cause these restlessness). Discontinue baclofen gradually over 2 wk or more. May effects, especially in elderly or debilitated patients. cause dizziness and drowsiness. Advise patient to avoid driving or other activities requiring alertness until response to drug is known. Instruct patient to change positions slowly to minimize orthostatic hypotension. Advise patient to avoid concurrent use of alcohol or other CNS depressants while taking this medication. Instruct patient to notify health care professional if frequent urge to urinate or painful urination, constipation, nausea, headache, insomnia, tinnitus, depression, or confusion persists. Nursing Process- Assessment Assessment Evaluation (Pre-administration assessment) Why would you hold or not give this med? Check after giving Assess muscle spasticity before and Abrupt cessation may result in fever, mental Observe patient for drowsiness, periodically during therapy status changes, exaggerated rebound dizziness, or ataxia. May be spasticity, and muscle rigidity. Advise patient alleviated by a change in dose. not to miss scheduled refill appointments and Decrease in muscle spasticity and to notify health care professional promptly if associated musculoskeletal pain with signs of withdrawal occur. Advise patient to an increased ability to perform report signs and symptoms of hypersensitivity activities of daily living (rash, itching) promptly.

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