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- - 2010

GENERICS

ORIGINAL

Units

Values

MT/TMX

Units

Values

MT/TMX

SIMVASTATIN

517,272

9,641,770.70

18.64

124,096

684,353.53

5.51

-13.12

-6,789,155.30

OMEPRAZOLE

451,165

6,847,346.87

15.18

252,502

2,247,690.26

8.90

-6.28

-2,831,223.53

ATORVASTATIN CALCIUM TRIHYDRATE

216,708

3,877,816.08

17.89

924,424

10,778,813.45

11.66

-6.23

-1,350,993.86

LEVOCARNITINE

260,522

2,921,896.84

11.22

70,683

361,589.39

5.12

-6.10

-1,589,157.84

CALCITONIN, SALMON

111,972

2,383,151.19

21.28

15,211

306,041.50

20.12

-1.16

-130,302.67

FLUCONAZOLE

81,858

2,000,089.93

24.43

10,433

96,534.05

9.25

-15.18

-1,242,677.46

10

CITALOPRAM

64,378

1,138,037.09

17.68

91,630

1,304,553.20

14.24

-3.44

-221,475.64

11

SALMETEROL XINAFOATE + FLUTICONASONE PROPIONATE

25,307

1,041,130.99

41.14

99,805

3,903,332.18

39.11

-2.03

-51,384.71

12

AMLODIPINE

129,393

905,271.35

7.00

457,509

1,819,247.26

3.98

-3.02

-390,750.63

13

ACETYLSALICYLATE LYSINE

1,169,871

837,454.90

0.72

77,827

52,171.33

0.67

-0.05

-53,231.87

14

BUDESONIDE

76,284

752,747.34

9.87

21,456

135,316.23

6.31

-3.56

-271,648.19

15

FERRIC HYDROXIDE POLYMALTOSE COMPLEX

135,796

723.638.90

5.33

47,552

150,347.88

3.16

-2.17

-294,284.91

16

LOSARTAN

52,658

721,996.61

13.71

53,424

672,924.48

12.60

-1.12

-58,720.61

17

PRAVASTATIN SODIUM

24,945

673,620.74

27.00

86,577

1,326,597.11

15.32

-11.68

-291,394.92

18

PURIFIED DIPHTERIA TOXOID + PURIFIED TETANUS TOXOID +

BORDETELLA PERTUSSIS

28,179

633,065.18

22.47

21,637

476,120.20

22.00

-0.46

-12,988.87

19

FERROUS SULPHATE DRIED

76,043

600,883.69

7.90

75,815

145,014.60

1.91

-5.99

-455,432.98

20

ACETYLCYSTEINE

139,445

599,835.04

4.30

10

12.10

1.21

-3.09

-431,106.59

21

BECLOMETASONE + FORMOTEROL

16,294

548,115.12

33.64

13,495

453,547.71

33.61

-0.03

-497.01

22

LOSARTAN POTASSIUM + HYDROCHLOROTHIAZIDE

34,729

509,894.35

14.68

52,879

708,643.93

13.40

-1.28

-44,482.84

23

MELOXICAM

62,448

496,146.41

7.94

62,258

367,223.65

5.90

-2.05

-127,802.06

24

CEFUROXIME

42,905

465,996.27

10.88

133,216

1,385,540.75

10.40

-0.48

-20,753.88

25

LISINOPRIL

69,393

389,177.28

5.61

73,188

294,226.04

4.02

-1.59

-110,207.67

26

LERCANIDIPI

36,191

360,486.06

9.96

48,048

442,298.99

9.21

-0.76

-27,334.99

27

ANTIRHEUMATIC N-S TOP

68,694

356,176.34

5.18

209,585

672,852.98

3.21

-1.97

-135,640.70

28

DIPHTHERIA TOXOID, ADSORBED + TETANUS TOXOID +

PERTUSSIS ACELLULAR (PERTUSSIS TOXOID, F HA, 69 KDA OU

16,475

345,152.98

20.95

18,731

255,047.57

13.62

-7.33

-120,823.86

29

FINASTERIDE

34,555

327,861.50

9.49

54,526

415,597.39

7.62

-1.87

-64,483.15

30

LANSOPRAZOLE

19,588

320,123.76

16.34

73,332

1,178,660.81

16.07

-0.27

-5,287.02

31

MIRTAZAPINE

16,915

314,836.03

18.61

59,796

999,879.88

16.72

-1.89

-31,991.56

32

ISOTRETINOIN

17,455

307,477.20

17.62

8,956

148,607.22

16.59

-1.02

-17,845.78

33

FILGRASTIM

881

292,620.57

332.15

827

259,885.43

314.25

-17.90

-15,765.60

34

ITRACONAZOLE

11,701

288,870.02

24.69

20,846

193,171.53

9.27

-15.42

-180,441.54

35

TAMSULOSIM

26,452

275,284.86

10.41

176,052

1,342,723.34

7.63

-2.78

-73,539.25

36

ONDANSETRON

5,778

273,112.34

46.92

4,069

132,985.40

32.68

-14.24

-82,272.42

37

FENTANYL

5,458

246,433.51

45.15

9,908

369,160.28

37.26

-7.89

-43,074.93

38

BUDESONIDE

12,497

238,616.57

19.09

126,330

2,356,708.14

18.73

-0.36

-4,493.63

39

ALLOPURINOL

111,211

208,145.11

1.87

192,494

176,340.50

0.92

-0.96

-106,265.59

40

BISACODYL

98,949

204,094.47

2.06

2.94

0.98

-1.08

-107,124.45

41

AMBROXOL

61,184

194,464.00

3.18

183,754

440,111.90

2.40

-0.78

-47,821.41

42

SODIUM CHLORIDE

229,455

189,795.93

0.83

42,217

28,105.96

0.67

-0.16

-37,036.31

43

SERTRALINE

16,975

188,065.44

11.08

108,024

864,953.68

8.01

-3.07

-52,145.75

44

CLINDAMYCIN

21,848

171,574.12

7.85

8,648

67,814.73

7.84

-0.01

-249.40

45

BENZOYL PEROXIDE

8,252

163,924.34

19.86

8,866

29,441.65

3.32

-16.54

-136,521.61

46

ENALAPR IL MALEATE + HYDROCH LOROTHIAZIDE

21,888

145,638.06

6.65

75,569

278,048.69

3.68

-2.97

-65,103.32

47

IMMUNOGLOBULIN HUMAN NORMAL

598

144,908.41

242.32

10

2,060.80

206.08

-36.24

-21,672.57

48

IOPAMIDOL

4,901

122,085.50

24.91

6,003

122,673.82

20.44

-4.47

-21,931.51

49

METFORMIN

67,669

112,315.60

1.66

671,065

1,096,635.06

1.63

-0.03

-1,732.87

50

KETOTIFEN

17,824

106,970.72

6.00

10,781

63,839.19

5.92

-0.08

-1,426.73

51

IODIXANOL

4,100

102,818.28

25.08

128

2,798.93

21.87

-3.21

-13,165.05

52

FLUTICASONE

5,263

102,124.11

19.40

80,350

1,056,255.94

13.15

-6.26

-32,938.36

53

CALCIUM CARBONATE + CHOLECALCIFEROL CONCENTRATE

17,124

95,826.26

5.60

173,348

912,614.76

5.26

-0.33

-5,674.57

18,223,488.97


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1) Benet LZ, Goyan JE, Pharmacotherapy 1995; 15:433-440.

2)  Sandimmun Neoral
3) Pollard S, Nashan B, Johnston A, et al., Clin Ther 2003 Jun; 25 (6): 1654-69
4) Guideline on the investigation of Bioequivalence, CPMP, January 2010,
EMEA
5) Helderman et al., Appl Health Econ Health
Policy 2010; 8 (1): 61-68

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