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Name: h f,Y
(points)

V

, t

1 l
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PHR 142P Quiz#8 - F2002

(2) 1 Ephedrineis a weakly basicdrug with Ku : 2.3 x IIa . Define intrinsic
partition coefficient for ephedrine.

V =::3 f\! [E]

,

fFl

[u: i, 6fc
\o

(2) 2. Define apparent partition coefficientfor a weak acid.

K*

:

lrrn]"
t-.^-1

LA-J* LHAJ,,n

r

'1

(2) 3. Write an equationwhich relatesKuoo pH for a weak acid. Be certain to

(4) 4.Sketch a graphof Kuoo pH for a weakacid. Indicatepredominant vs species at variouspoints on the graphand indicatesignificant features just as has beendone in lecture.

Ko u,.{

H.K K,7,

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