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Hirotaka Nagai - CV

Hirotaka Nagai - CV

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Published by Hirotaka Nagai
Curriculum vitae of mine. Updated in April 8th 2012.
Curriculum vitae of mine. Updated in April 8th 2012.

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Published by: Hirotaka Nagai on Nov 30, 2011
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Hirotaka Nagai (永井裕崇) --- Curriculum Vitae (1) Personal Information

Date of birth: November 12th, 1985 Address: Department of Pharmacology, Kyoto University Graduate School of Medicine, Konoe-cho Yoshida, Sakyo-ku, Kyoto-shi, Japan Tel: +81-75-753-4399 Email: h-nagai at mfour.med.kyoto-u.ac.jp, nagai at med.nagoya-u.ac.jp Web sites: http://scholar.google.com/citations?hl=en&user=ABUdp68AAAAJ http://www.researcherid.com/rid/C-9713-2010

(2) Present Appointments
Faculty of Medicine, Kyoto University, Japan B.S. in Medicine (M.D./Ph.D. Program) Department of Pharmacology, Kyoto University, Japan Visiting postdoctoral fellow Apr 2012 – Present Mar 2012 – Present

Department of Pathology and Biological Responses, Nagoya University, Japan Visiting Researcher Apr 2012 – Present

(3) Previous Appointments
Japan Society for the Promotion of Science (JSPS), Japan DC1 fellow Apr 2009 – Mar 2012 Department of Pathology and Biological Responses, Nagoya University, Japan Visiting student Aug 2008 – Mar 2012 Department of Pathology and Biology of the Diseases, Kyoto University, Japan Ph.D. in Pathology (M.D./Ph.D. Program) Apr 2008 – Mar 2012 Faculty of Medicine, Kyoto University, Japan B.S. in Medicine Apr 2004 – Mar 2008 Eiko Gakuen High School, Japan High school student Apr 2001 – Mar 2004

(4) Journal Articles
1. Nagai, H., Okazaki, Y., Chew, S. H., Misawa, N., Yamashita, Y., Akatsuka, S., Ishihara, T., Yamashita, K., Yoshikawa, Y., Yasui, H., Jiang, L., Ohara, H., Takahashi, T., Ichihara, G., Kostarelos, K., Miyata, Y., Shinohara, H., Toyokuni, S. (2011) Diameter and rigidity of

multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis. Proc Natl Acad Sci USA 108:E1330-1338. Selected as a research highlight in Proc Natl Acad Sci USA, Dec 2011, volume 108 no. 49; as a research highlight in brief in Nat Rev Cancer, Jan 2012, volume 12 issue 7. Reported in several newspapers (Asahi, Nikkei, Chunichi, Nikkan-kogyo and Shinano-mainichi) and on TV news (NHK and NHK world). 2. Nagai, H., Ishihara, T., Lee, W. H., Ohara, H., Okazaki, Y., Okawa, K., Toyokuni, S. (2011) Asbestos surface provides a niche for oxidative modification. Cancer Sci 102: 2118-2125. Selected as a research highlight in Cancer sci, Dec 2011, volume 102 issue 12. Ohara, H., Akatsuka, S., Nagai, H., Liu, Y. T., Jiang, L., Okazaki, Y., Yamashita, Y., Nakamura, T., Toyokuni, S. (2011) Stage-specific roles of fibulin-5 during oxidative stressinduced renal carcinogenesis in rats. Free Radic Res 45:211-220. Hu, Q., Akatsuka, S., Yamashita, Y., Ohara, H., Nagai, H., Okazaki, Y., Takahashi, T., Toyokuni, S. (2010) Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. Lab Invest 90:360-373. Jiang, L., Nagai, H., Ohara, H., Hara, S., Tachibana, M., Hirano, S., Shinohara, Y., Kohyama, N., Akatsuka, S., Toyokuni, S. (2008) Characteristics and modifying factors of asbestos-induced oxidative DNA damage. Cancer Sci 99:2142-2151.

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(5) Review Articles, Book Chapter
1. Toyokuni, S., Jiang, L., Hu, Q., Nagai, H., Okazaki, Y., Akatsuka, S., Yamashita, Y. (2011) [Mechanisms of asbestos-induced carcinogenesis] (Japanese). Nihon Eiseigaku Zasshi 66:562-567. Nagai, H., Toyokuni, S. (2011) in Advanced Applications of Nanocarbon Materials (Japanese), ed. Shinohara, H. (CMC Publishing CO., LTD.), pp. 265-273. Nagai, H., Toyokuni, S. (2011) How fibrous particulate materials cause diseases: A review on the mechanisms of mesotheliomagenesis. Transactions of the Materials Research Society of Japan 36:47-50. Nagai, H., Toyokuni, S. (2010) Biopersistent fiber-induced inflammation and carcinogenesis: lessons learned from asbestos toward safety of fibrous nanomaterials. Arch Biochem Biophys 502:1-7.

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(6) Invited Seminar
The University College London School of Pharmacy, London, UK Invited by Dr. Kostas Kostarelos Oct 19th 2010

(7) Awards, Honours, Qualifications
The 4th Global COE Retreat, Nagoya University Graduate School of Medicine (Obu, Japan) Best Discusser Award Feb 2012 Workshop: Paradigm of Cancer Research at an Individual Level (Otsu, Japan) Best Discusser Award Annual Meeting of the American Society for Cell Biology 2011 (Denver, USA) Predoctoral Travel Award The 12th Wrokshop for Young Cancer Scientists (Tateshina, Japan) 2nd Best Oral Presentation Award & Best Discusser Award

Jan 2012

Dec 2011

Sep 2011

The 3rd Global COE Retreat, Nagoya University Graduate School of Medicine (Obu, Japan) Best Presentation Award Feb 2011 The Global COE Retreat 2010, Kyoto University Graduate School of Medicine (Awaji, Japan) Best Presentation Award Nov 2010 The 2nd Global COE Retreat, Nagoya University Graduate School of Medicine (Obu, Japan) Best Discusser Award Feb 2010 Kyoto University President Prize Lipid Peroxidation 2008 (Nagano, Japan) Young Investigator Award The 97th Conference of the Japanese Society of Pathology (Kanazawa, Japan) Student Poster Award WJEMA Summer Conference 2005 (Osaka, Japan) The Best Debater Prize WJEMA Summer Conference 2004 (Kyoto, Japan) The 3rd Speech Prize

Mar 2009

Oct 2008

May 2008

Aug 2005

Aug 2004

TOEFL iBT 94/120 TOEIC 925/990

May 2010 May 2010

(8) Grant

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research; 2,100,000 yen (27,000 $) in total

Apr 2009 – Mar 2012

(9) Teaching
Pathology course, Nagoya University Faculty of Medicine Teaching assistance Pathology course, Kyoto University Faculty of Medicine Teaching assistance 2009 - 2011 2008

(10) Research Experience
Fiber-induced carcinogenesis Apr 2007 – Mar 2012 We studied how fibers in nano-scale such as asbestos fibers and multiwalled carbon nanotubes cause cancer. We found that carbon nanotubes enter mesothelial cells in a different way than asbestos fibers do. In more detail, thinner and more rigid nanotubes are better able to pierce the nuclear and outer membranes of mesothelial cells, compared with thick and tangled nanotubes. We believe that safer nanotubes might be produced based on these findings. Updated: April 8th 2012

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