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The structure of the female breast is complex including fat and connective tissue, as well as lobes, lobules, ducts and lymph nodes Each breast has 15 to 20 lobes. Each lobe has many smaller lobules, which end in dozens of tiny bulbs that can produce milk. Fat fills the spaces between lobules and ducts. There are no muscles in the breast, but muscles lie under each breast and cover the ribs.
Each breast also contains blood vessels and vessels that carry lymph.
LYMPHATIC DRAINAGE
4main routes: laterally: anterior axillary nodes medially: internal thoracic nodes cutaneous nodes of the contralateral breast superiorly: apical axillary nodes medial axillary nodes inferiorly: cutaneous lymphatics of the superior abdominal wall the liver
MASTOPATHY
Mastopathy is a breast disease manifested by pathological growth of breast tissue. Mastopathy is a background disease mostly common for women in the age between 17 and 45. The main complaints include breast pains caused by neoplasm. Moreover, later the mastopathy has potential to transform into cancer.
TYPES
Diffuse
Fibrous Cystfibrous
Nodular
Fibrous Cystfibrous
DIFFUSE MASTOPATHIA
Usually in young female Location: usually on upper outer quadrant Complaints: constant pain which increase in 2nd part of menses; discharge may be present or absent Palpation: slightly firm mass in upper outer quadrant in upright position, mass decrease or unpalpable when patient is lying down
NODULAR MASTOPATHIA
Usually in elder female Complaints: constant pain which increase in 2nd part of menses; discharge may be present or absent Palpation: slightly firm mass in upper outer quadrant in upright position, mass do not decrease when patient is lying down
The woman can be exposed to mastopathy at any time at the very beginning of growing-up when the endocrine profile is just being established, and before menopause when endocrine profile is distorted.
The mastopathy is a misbalance of the endocrine profile that causes changes in mammary glands.
CLINICAL SYMPTOMS
breast pains / discomfort premenstrual breast engorgement in the middle of the cycle (for 2-3 days before the menstrual period is usual) lump in the breast skin changes in the breast nipple disorders - feels bulging of the nipples - sanies from the nipples
TREATMENT
Non-operative or surgical. Non-operative treatment supposes drug therapy: pills, creams, herb teas. Surgical treatment supposes operative intervention and is applied in much neglected cases.
PROGNOSIS
If a women goes to the doctor in time, in 90 per cent of cases the therapeutic treatment is enough. In neglected and extreme case, it can transform into cancer or adenoid tumors. Adenoid tumors are benign nodes that can transform in cancer if neglected.
Clinical Presentation Presents either as a single lump or areas of lumpiness which are painful and tender premenstrually
2. FIBROADENOMA
-
small, solid, rubbery, noncancerous, harmless lumps composed of fibrous and glandular tissue, localised form of ANDI Clinical Presentation
- Most common between ages of 15-30 Single rounded mass, smooth, firm and highly mobile - Breast Mice
!!! Must be small lesions, bacause larger fribroadenomas should be distinguish from benign phylloids tumour!!!
- Multiple and Bilateral
FEW EXAMPLES
3. DUCT PAPILLOMA
Localised areas of epithelial proliferation
Clinical Presentation
- Usually occurs as solitary lesions in the main lactiferous ducts, close to the nipple - Multiple, occur more peripherally - Present as spontaneous, blood-stained or clear watery nipple discharge
MANAGEMENT
Papillomas are treated by excision of affected duct Microdochectomy or a group of ducts, wedge resection
!!! If the causative lesion can't be found on the operation, a subareolar excision of all the ducts may be necessary!!!
4. FAT NECROSIS
Clinical Manifestation can simulate carcinoma clinically and mammographically history of antecedent trauma, prior surgical intervention lipidfilled cysts
5. BREAST INFECTIONS
a. Cellulitis - diffuse inflammation of CT with severe inflammation of dermal and subcutaneous layers of the skin - Early phase is reversible if treated with antibiotics (Flucloxacillin) b. Abcess - results of inadequately treated cellulites - red, painful, tender, warm - pus formation
Infections of the breast lobules Group A Streptococcus and Staphylococcus are the most common of these bacteria
6. DUCT ECTASIA
- Dilatation and shortening of major lactiferous ducts - Appears around menopause - Half of all women >60 years old
Clinical manifestations
- Ductal discharges ranges from creamish to blue green - Nipple retraction - Palpable mass !!! Plasma cells characteristic feature in histology Plasma cell Mastitis
Management
- Antibiotics
Physiological: at birth in response to maternal oestrogens crossing placenta Medication: Spironolactone, Digoxin, Isoniazid Pathological: Liver disease