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Published by: Shizuka Marycris Amane on Jan 02, 2012
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Drugs mucosta http://www.scribd.

com/doc/41547204/Grp25-Rivera-Mikhail-Bien-MICU-Drug-Study http://www.mims.com/Philippines/drug/info/Mucosta/Mucosta%20tab? q=mucosta&type=brief http://www.mims.com/Malaysia/drug/info/Mucosta/Mucosta%20film-coated%20tab? type=full http://bsnurse.com/?p=1293

http://www.mims.com/Philippines/drug/in fo/Plogrel/Plogrel%20film-coated %20tab?type=full#Actions http://test.thefilipinodo ctor.com/search-drugdetails.php? keyword=Drugmaker %5C's%20Biotech %20Aspirin&id=2009 0086&secid=20071382 &sec1id=20020009&se c2id=20030006&sec3id =20070014&sec4id=

Active Duodenal Ulcer. and diarrhea occurs. Side Effects and Adverse Reactions of Omeprazole Side Effects of Omeprazole o Headache o Diarrhea o Abdominal pain o Nausea o Dizziness o Asthenia (loss of strength) o Vomiting o Constipation o Upper respiratory tract infection o Back pain o Rash o Cough Adverse Reactions of Omeprazole None known. Patient Teachings for Clients Taking Omeprazole o Report headache o Do not chew or crush tablets o Take before eating Brand name: Senokot 187 mg Tablet/ granules Category: laxative Formulation: Tablets – each tablet contains 187 mg equivalent standardized senna concentrate Granules – each teaspoonsful contains 337 mg equivalent standardized senna concentrate For reliable of functional constipation through gentle. Prevention or Treatment of NSAIDInduced Ulcers PO: ADULTS.Omeprazole Omeprazole is used to treat conditions where there is an increase in the gastric acid of the stomach. Poorly Responsive GERD. pylori associated with duodenal ulcer and active benign gastric ulcers. In the colon. effective peristaltic stimulation. Nursing Considerations for Clients Taking Omeprazole o Give before meals o Do not crush or chew tablets. ELDERLY: 20 mg per day. It is also used in the prevention and treatment of NSAID-induced ulcers. Acipres. Common brand names are Acifre. swallow whole o Evaluate for therapeutic response like relief of Gastrointestinal symptoms o Question if Gastrointestinal discomfort. Flazomel. Action of Omeprazole Omeprazole is converted to active metabolites that irreversibly bind and inhibit H+-K+-ATPase (an enzyme on the surface of gastric parietal cells). Active Benign Gastric Ulcer PO: ADULTS. Lomezek. Losec. It is a maintenance healing of erosive esophagitis. Omeprazole is classified as a Benzimidazole and a Gastric acid pump inhibitor. Megapraz. Omeprazole can also be used in the treatment of H. exert no action in the stomach or small intestine. Risek. It inhibits transport of hydrogen ions into the gastric lumen. Usual Dosage for Children >2 years PO: (GERD. nausea. erosive gastritis): <20 kg: 10 mg per day. ELDERLY: 20 mg two times per day for 10 days. Gastriloc. >20 kg: 20 mg per day. upon ingestion. Lopep. 60 mg per day up to 120 mg three time a day. Prosec. ELDERLY: 40 mg per day for 4-8 weeks. ELDERLY: Initially. Omeprazole increases the gastric pH and reduces gastric acid formation. according to current . Pathologic Hypersecretory Conditions PO: ADULTS. Pylori Duodenal Ulcer PO: ADULTS. Ulsek. and Zosec. Omeprazole is used for the long-term treatment of pathologic hypersecretory conditions and active duodenal cancer. ELDERLY: 20 mg per day. Routes and Dosage of Omeprazole Erosive Esophagitis. Omelon. Omepron. yet gentle peristalsis -does not act by irritation of the colonic mucosa -have virtually no effect on motility of the stomach and small intestine Mechanism of action: Senokot preparations contain glycosides (the natural principles of senna) which. Nocid. Loprezol. Hovizol. Mepraz. Maintenance Healing of Erosive Esophagitis PO: ADULTS. Indications for Omeprazole Shot-term treatment for erosive esophagitis and symptomatic gastroesophageal reflux disease (GERD) poorly responsive to other treatment. H. -have virtually colon-specific action. Prexon. Mepracid. inducing efficient. Famazol.

and easy evacuation the following morning.571 patients reported in 31 clinical studies. help induce comfortable evacuation of well-formed stools. Economical. nausea.decrease myocardial oxygen requirement by decreasing the heart rate. ventricular volume. Clinically confirmed: Over a decade of wide clinical experiences and a wealth of published clinical and pharmacologic evidence have established Senokot Tablets/granules as a laxative of choice in functional constipation. Drug Classification: Anti-Anginal Drugs Mechanism of Action: acts by directly counteracting all the major metabolic disorders occurring within the ischemic cell. or persistent diarrhea. blood pressure and contractility. . Dosage: 1 tab morning and evening Special Precaution: Pregnancy and Lactation Pregnancy Risk Category: Adverse Reaction: Rare cases of GI disorders.9% of 7. If comfortable bowel movement is not achieved by the second day. or gripping that occur with orindary laxatives and harsh purgatives. vomiting. Store at temperature not exceeding 30 degrees Celsius Brand Name: Vastarel MR Generic Name: Trimetazidine Indication: Long treatment of coronary insufficiency. Senokot preparations help to: -relieve and control chronic constipation -lighten the burden of constipation in the aged -gently relieve constipation of pregnancy and the puerperium -counteract and prevent drug-induced constipation -smoothly relieve post-surgical constipation -mitigate the hazards of constipation in cardiovascular disorders -facilitate dieting without constipation -solve the problem of chronic constipation in chronic illness -help ease the stress and distress of constipation associated with hemorrhoids Virtually Free from side effects: The action of Senoko tablets and granules is virtually limited to the colon. easy to swallow tablets. usually within 8 to 10 hours. or other symptoms of appendicitis are present. or obstruction . Its high degree of effectiveness is reflected in satisfactory evacuation achieved in 95. enzymatic action converts the inactive glycosides into active aglycones which act specifically in the large bowel through the auerbach’s plexus to stimulate peristalsis. Reliable. In granules. there is usually no intestinal turmoil. Gentle yet effective: Senokot tablets and granules. Rehabilitation potential: Senokot tablets and granules aid in rehabilitation of the constipated patient by facilitating regular elimination. In some cases. Optimal dosage flexibility to meet the individual needs of your patients. This permits administration at bedtime. High patient acceptance Delicious chocolate-flavored granules.theory.27kg): one tablet (Maximum dose: 2 tablets two times a day) Granules: Adult: 1 teaspoonful (maximum dose: 2 teaspoonsful twice a day) Children above 60 lbs (27. angina pectoris. In proper dosage. small. myocardial oxygen delivery is increased thru reversing coronary arterial spasm. and prevention of excessive production of free radicals. acute abdominal diseae. decrease or incrase dose by one-half teaspoonful (up to maximum dosage). increase recommended dose by one tablet (up to maximum dosage) or decrease until the most effective dose is established. correction of disturbances of transmembrane ion exchanges. cramping. Contraindication do not use when abdominal pain. Dosage and Administration: Tablets: (preferably at bedtime) Adult: 2 tablets (maximum dose: 4 tablets two times a day) Children above 60 lbs (27. by their gentle peristaltic stimulation of the colon. Contraindications: MAOI’s (monoamine oxidase inhibitors) Form: 35 mg tablets Nursing Responsibility:  use cautiously in patients with heart failure or hypertension and in elderly patients. The actions of trimetazidine include limitation of intracellular acidosis. intestinal hemorrhage.27kg): one-half teaspoonful (maximum dose: 1 teaspoonful twice a day) Dosage can be adjusted to meet individual requirements.

pregnancy. pronounced dizziness. noise. R. CHF Physical: Skin lesions. fluid retention Side Effects: hypernatremia. use special caution if patient has CHF. lethargy CV: Peripheral edema. the plasma contains 136-145 mEq/L and 98-1-6 mEq chloride/L. decreased cardiac oxygen consumption. and dilation of coronary arteries and arterioles and peripheral arterioles. alone or in combination with other antihypertensives Contraindications: Contraindicated with allergy to amlodipine. CNS: Dizziness.Observe S&S of hypernatremia. These side effects may occur: Nausea. depression of myocardial contractility. Fluid and solute overload leading to dilution of serum electrolyte level. these Generic Name: furosemide Trade name: Lasix Classification: Loop Diuretic Action: Inhibits reabsorption of sodium and chloride at proximal and distal tubule and in the loop of Henle. which is often treated with diuretics. frequent meals). lactation. auscultation. acute pulmonary edema Nursing Responsibilities: a. It plays a crucial role in maintaining the fluid and electrolyte balance. peripheral perfusion.8 g Mode of Action: sodium is the major cation of the bodys extracellular fluid. light-headedness. alone or in combination with other agents Essential hypertension. impaired hepatic or renal function. abdominal discomfort Assessment History: Allergy to amlodipine. adventitious sounds. inhibits transmembrane calcium flow. hypernatremia. cardiac rhythm. Use cautiously with CHF.Note level of consciousness c. Normally. increased delivery of oxygen to cardiac cells Indications: Angina pectoris due to coronary artery spasm (Prinzmetal's variant angina) Chronic stable angina. impaired hepatic or renal function. severely impaired renal function. Anti-Anginal/ Anti-hypertensive Inhibits the movement of calcium ions across the membranes of cardiac and arterial muscle cells. urinalysis Interventions Monitor patient carefully (BP. liver and renal function studies b. liver evaluation. acidosis. CHF. overhydration. liver and renal function tests. baseline ECG. lactation. sick sinus syndrome. and output) while adjusting drug to therapeutic dose. Teaching points Take with meals if upset stomach occurs. total daily dose should not exceed 4. BP. headache. Abnormally low levels of sodium result indehydration. hypervolemia). constipation. the averagedaily requirement of salt is approximately 5g. elevated temperature. headache (adjust lighting.Monitor VS and I&O f. asthenia. heart block (second or third degree). Excess retention of sodium results in overhydration(edema. P. Monitor BP very carefully if patient is also on nitrates. Drug-Drug Interaction: Contraindication: congestive heart failure. prevention or treatment of extracellular volume depletion Ordered dose: 1 tab TID 6-12-6 Dosage: 0. and temperature. color. chloride deficiency due to dieresis or salt restrictions. which results in the depression of impulse formation in specialized cardiac pacemaker cells. arrhythmias Dermatologic: Flushing. swelling of the hands or feet. hypopotassemia. fatigue. ECG. Administer drug without regard to meals. sick sinus syndrome. Monitor cardiac rhythm regularly during stabilization of dosage and periodically during long-term therapy.Generic Name: sodium chloride Classification:e le ctroly te Pregnancy category:C Indication: prophylaxis of heat prostration or muscle cramps.Assess urine specific gravity and serum sodium levels Amlodipine 10mg/tab OD po Norvasc effects lead to decreased cardiac work. shortness of breath. rash GI: Nausea. slowing of the velocity of conduction of the cardiac impulse. Used in treatment of Pulmonary Edema .Assess the heart and lung sounds d. vomiting (eat small.Monitor electrolytes. flushed skin. GI normal output. rough dry tongue. and edema e.5  1 g with 8 oz water up to 10 times/day. heart block. edema. and in patients with vasospastic (Prinzmetal's) angina. Report irregular heartbeat. medication may be ordered).

Side Effects: Headache. NSAIDs (e. heparin). vasculitis. thrombotic thrombocytopenic purpura (TTP).g. hypochromic anemia. Weighpatient daily under standard conditions. pulmonary hemorrhage. taste disorder. cardiac failure. eczema. dizziness. and patients with non-ST segment elevation acute coronary syndrome (unstable angina/non-Q wave MI) including patients who are managed medically with percutaneous coronary intervention (with or without stent) or Coronary Artery Bypass Graft. retroperitoneal bleeding. pruritus. clarithromycin. hallucination. rhinitis. diarrhea Nursing Implication: closely monitor vital signs. hyperuricemia. Neuromuscular and skeletal: Arthralgia. leg cramps. hypertension. simvastatin). Report decrease or unusual increase in output. ocular hemorrhage. Cardiovascular: Chest pain. palpitation. argatroban. ascites. Maximum 600mg/day. lichen planus. ischemic necrosis. thrombocytopenia. gastritis. atrial fibrillation. CNS: Headache. bilirubinemia. maculopapular). anemia. loss of hearing. neuralgia. fever. weakness. hepatic disease. cystitis. Miscellaneous: Flu-like syndrome. allergic reaction. Route: PO (Oral Route) Tablet or solution Intramuscular injections Intravenous Dosage: PO 20-80mg/day. intracranial hemorrhage. diclofenac). edema. urticaria. Monitor Intake and output. gout. Side Effect: Gastrointestinal effects: Abdominal pain. Immunologic: Serum sickness. drugs metabolized by CYP2C9 isoenzyme (e. atorvastatin.. bivalirudin.Sudden alteration in fluid and electrolyte balance may precipitate significant adverse reactions. erythromycin. Potassium chloride Kalium durule Drug Class: Electrolytes and minerals .in CHF. macrolide antibiotics (e. troleandomycin). severe hepatic or renal impairment. confusion. Orthostatic Hypotension. erythema multiforme. fluvastatin). Precaution: Cases of thrombocytopenic purpura. naproxen.. insomnia. EndocrineMetabolic: Hypercholesterolemia. polyuria. urgent plasmapheresis is required. neutropenia. hepatitis. and hypotension. fatty liver. menorrhagia. pruritus. Average dosage is 233mg. Stevens Johnson syndrome. agranulocytosis. paresthesia. ibuprofen. Monitor for signs and symptoms of hypokalemia. circulatory collapse. conjunctivitis. Respiratory: Dyspnea. hemoptysis. nephritic syndrome. pancytopenia. and children <21 years old. except in patients with cardiac stents that have not completed their full course of dual antiplatelet therapy. torsemide. syncope. anxiety. hemothorax. Prophylaxis as an alternative to aspirin in patients at risk of thromboembolic disorders Contraindication: Hypersensitivity. Excessive diuresis can result in dehydration and hypovolemia. tamoxifen. breastfeeding mothers. interstitial pneumonitis. statins and cyclosporin (e. vomiting.. recent ischemic stroke (from 7 days until <6 months) or established peripheral arterial disease. Presence of any pathological bleeding or coagulation disorders. diarrhea. Patients with platelet disorders and/or at increased risk of bleeding. depression.g. cough. warfarin. vertigo. bullous eruption. fatigue. arthritis. toxic epidermal necrolysis. stomatitis.. Generic Clopidogrel Drug Class: Cardio/ Anticoagulants/Antiplatelets/Thrombolytics/ Antiplatelet Agents Indications: Prevention of atherosclerotic events in patients with history of recent myocardial infarction or MI (within 7 days from occurrence). and hypertension. bronchospasm. lovastatin. Hepatic: Liver function test abnormalities. pancreatitis. upper respiratory infection. bupropion. Derma: Rash (severe. Drug Interaction: Aspirin. Consider discontinuing clopidogrel 5 days before elective surgery. angioedema. hypersensitivity. gastrointestinal hemorrhage. Genitourinary: UTI. anaphylactoid reaction. enoxaparin. general pain. nausea.g. acute liver failure. leukopenia. granulocytopenia. hematuria. hemorrhagic stroke. back pain. anticoagulants (e. hematoma. Hematologic: Bleeding. bronchitis. dyspepsia. epistaxis.g. Ocular: Cataract.. Pregnant women. tolbutamide. pancreatitis. aplastic anemia. Observe older adults closely during period of brisk diuresis .g. constipation. phenytoin.

hypotension. . diarrhea. nausea. Side effect Headache. untreated Addison’s disease.  Tell the patient to take drug at least 1 hour before a meal. headache. palpitations. hyperkalemia. Advise patient to report signs of superinfection (furry overgrowth on the tongue. ADVERSE EFFECT Diarrhea. or mucus. vomiting. diarrhea. Short . Ceftriaxone third-generation cephalosporins MOA Bind to the bacterial cell wall membrane. Urinary and gynecologic infections including gonorrhea or respiratory tract infections. Alcohol and alcohol-containing medications should be avoided during and for several days after therapy. thus reducing gastric acidity. Indications: Treatment of respiratory tract infectio Skin and skin structure infections. Advise patient not to treat diarrhea without consulting health care professional. vomiting. Misc: allergic reactions including ANAPHYLAXIS and SERUM SICKNESS. Nurcing management  Instruct patient to take drug exactly as prescribed. Children. constriction of the esophagus and or obstructive changes in the alimentary tract. flatulence. constipation. • Watch out for possible adverse reaction of the patient. stomach pain. Nexium blocks the final step in acid production. GI: PSEUDOMEMBRANOUS COLITIS. PATIENT/FAMILY TEACHING Instruct patient to take medication at evenly spaced times and to finish the medication completely. Bone and joint infections. CNS: SEIZURES (high doses).  Advise patient that antacids can be used while taking drugs unless otherwise directed by prescriber. Hypersensitivity to L-arginine (Ceptaz formulation only). nausea. Local: pain at IM site. do not double doses. Antireflux Agents & Antiulcerants MOA Nexium(esomeprazole) is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of H+/K+-ATPase in the gastric parietal cell. vaginal itching or discharge. vomiting. flushing). Hemat: bleeding. especially if stool contains blood. loose or foul-smelling stools) and allergy.term maintenace of hemostasis & prevention of rebleeding in patients following therapeutic endoscopy for acute bleeding of gastric or duodenal ulcers. • Observe 10 rights of giving medication. Indication Treatment of GERD as an alternative to oral therapy in patients when oral therapy is not appropriate. hemolytic anemia. Carnitine deficiency or inborn errors of metabolism (cefditoren only). Contraindication Hypersensitivity to substituted benzimidazoles. Serious hypersensitivity to penicillins. Esomeprazole Brand Name: Nexium Antacids. Caution patients that concurrent use of alcohol with cefoperazone may cause a disulfiram-like reaction (abdominal cramps. even if feeling better. Instruct patient to notify health care professional if fever and diarrhea develop. superinfection. blood dyscrasias. pus. This effect is dose-related up to a daily dose of 20–40 mg and leads to inhibition of gastric acid secretion. Injection site reaction. Septicemia Contraindicated in: Hypersensitivity to cephalosporins. sweating. nausea. phlebitisat IV site. discomfort or gas vomiting NURSING RESPONSIBILITIES • Watch out for levels of potassium electrolyte level to prevent hyperkalemia. Missed doses should be taken as soon as possible unless almost time for next dose. Intra-abdominal infections. abdominal pain. nausea. pseudolithiasis (ceftriaxone). Derm: rashes. tachycardia.indication Hypokalemia Mode of action Provides a direct replacement of potassium in the body CONTRAINDICATION Renal insufficiency. By acting specifically on the proton pump. cramps. Advise patient that sharing of this medication may be dangerous. dyspnea. urticaria. causing cell death.

heart or lung transplant. It appears that the C8methoxy moiety contributes to enhanced activity and lower selection of resistant mutants of Gram-positive bacteria compared to the C8-H moiety. diarrhea. pain at I. beta-lactams. neutropenia. therfore. brain stem dysfunction. agranulocytopenia.Avelox I. and seek immediate medical attention if you develop joint/muscle/tendon pain or swelling. Seek immediate medical attention if you develop muscle weakness or trouble breathing. Acute gastritis & acute exacerbation of chronic gastritis. dizziness. tendinitis.. pruritus.g. aplastic anemia HEPATIC: hepatitis Other: altered tasye. Treatment was discontinued due to drug-related adverse reactions in 5. nausea. Your risk for tendon problems is greater if you are over 60 years of age.prostaglandin biosynthesis and decrease free oxygen radicals.6% discontinuation due to adverse effects. hypersensitivity • Monitor for resolution of GI symptom • Assess CBC in liver function tests • Assess constipation Monitor electrolytes levels as appropriate . skin structure infections Side Effects Most adverse reactions to Avelox in clinical trials were mild to moderate. the most common adverse effects were the following: • Nausea (7%) • Diarrhea (6%) • Dizziness (3%) Mechanism of Action Moxifloxacin has in vitro activity against a wide range of Gram-positive and Gramnegative microorganisms. rest. Anti reflux Agents & Antiulcerants Rebamipide is a mucosal protective agent and is postulated to increase gastric blood flow . aminoglycosides. drowsiness. The bactericidal action of moxifloxacin results from inhibition of the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication. peripheral-neuropathy. CNS: confusion. or tetracyclines. saw 3. arrhythmias. cardiac arrest GI: nausea. thrombocytopenia.V. It may cause the condition to become worse. (moxifloxacin hydrochloride) Company: Bayer Approval Status: Approved November 2001 Treatment for: Susceptible strains of sinusitis. microorganisms resistant to these classes of drugs may be susceptible to moxifloxacin and other quinolones. or if you have had a kidney. associated with the NorA or pmrA genes seen in certain Gram-positive bacteria. repair.7% of patients treated sequentially (intravenous followed by oral) in the trials in which the patient population had community acquired pneumonia. (From Avelox package insert) This medication may rarely cause tendon damage (e. constipation HEMA: anemia. Rash.a ctation. in themorning. evening and before bed. Dosage: Oral Peptic ulcer. is different from that of macrolides. Moxifloxacin should not be used in patients with myasthenia gravis. transcription. GenericName Rebamipide Brand Name: Mucosta DrugClassification: Antacids. The trials in which patients were treated with the tablet form of Avelox alone. and recombination. There is no known cross-resistance between mosifloxacin and other classes of anitmicrobials.M injection site. CV: hypotension. In clinical trials. Stop exercising. The presence of the bulky bicycloamine substituent at the C-7 position prevents active efflux. hallucination. The mechanism of action for quinolones.Gastritis Adult: 100mg tid. if you are taking corticosteroids (such as prednisone). tendon rupture) during or after treatment. diarrhea. constipation. Gastric ulcer. bronchitis. including moxifloxacin. pneumonia.

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