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First produced by German Chemists in early 20th century and has been used clinically since end of WW1. Synthetic opiate without strong sedative effects. Widely used as a substitution therapy in the treatment of heroin addiction. White crytalline powder. Methadone can be administered orally in tablet or syrup forms thus avoiding injections and the possible associated risks of sharing needles and syringes and other injection paraphernalia.
Effects felt within one hour, peak at 4 to 8 hours after the dose and last longer (up to 24 hours) thus given once a day. Daily dosages vary from 40mg-100mg. Can caused dependence of a lesser nature than that of other opiates. People can stop using methadone by reducing the dose gradually.
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