86892

' :

SKY - FISH
040537391 060140209 :

1

FISH ± FISH ± M-FISH ± SKY ± SKY -         2 .

Multi-color FISH .± (1960) Staining Protocols ‡ . .SKY ‡ 3 . .FISH ‡ .

DNA / . ‡ . ‡ . ) . DNA .( 4 . . ‡ ‡ .

‡ ‡ .FISH ± ‡ FISH ± Florescence In-Situ Hybridization . 5 ‡ .(Probes) .(cytogenetics) .

FISH - .

(2) FISH ± 7 .

(3) FISH ± Detector mercury/xenon Lamp Exciter filter Collimating Lens Barrier filter Dichroic filter Objective lens .

Multicolor FISH ± Cross talk 9 .

Multicolor FISH ± 10 .

± ‡ . . . 11 ± ± .Multicolor FISH ± ‡ ± ± .

Karyotyping ‡ .( ' ) .Spectral ± Karyotyping (SKY) ‡ .eukaryotic 12 .

SKY - 13 .

.1 14 ‡ .SKY .zero filling ‡ . ‡ (Apodization) Interferometer .

SKY (2) 15 .

. . .. . 16 ‡ ‡ ‡ ‡ ‡ ‡ .SKY . .

‡ ‡ .Multi-color FISH . . ‡ 17 .

(2) ± SKY . ‡ . ‡ . ‡ . 18 ‡ .

Katzir N. Vol.J. Garini Y. Macville M. 6572  Trask B.Spectral karyotyping. pp.. BarAm I. Schröck E. pp. 3 no. IOP publishing Ltd. 10. . Nature Reviews/Genetics. Cabib D... 769-778   Wikipedia 19 . de Manoir S. Wine D. Lavi M. Buckwald.. 1996. 2002.. & Ried T. Human Cytogenetics: 46 Chromosomes.. 46 Years And Counting..

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