VACCINES:INTRODUCTION & BASICS

as used by Edward Jenner(1796) which provided protection against small pox in humans. improves immunity to a specific disease. .SOME BRIEF POINTS ‡ Biological preparation. ‡ These agents stimulate the body's immune system to recognize and destroy them. ‡ The term vaccine is derived from cow pox. ‡ Usually contains a weakened/semikilled/attenuated form of a microbe(or their toxins).

Their different types: ‡ Killed ‡ Attenuated ‡ Toxoid ‡ Subunit ‡ Conjugate ‡ Experimental ‡ Valence .TYPES Vaccines are dead or inactivated organisms or purified products derived from them.

cholera . bubonic plague. ‡ Examples : Influenza. hepatitis A . etc.Killed vaccines ‡ They contain killed microbes that were virulent earlier. . ‡ May be destroyed with chemicals . heat. rabies vaccine . radioactivity or antibiotics.

.Attenuated vaccines ‡ Contain live (attenuated) micro-organisms. ‡ These agents provoke more durable immunological responses and are the preferred type for healthy adults.

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