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U.P.

TECHNICAL UNIVERSITY, LUCKNOW

   

Syllabus

1st , 2nd , 3rd and 4th Year
[Effective from session 2009-10]

BACHELOR OF PHARMACY 

1   

U.P. TECHNICAL UNIVERSITY LUCKNOW
STUDY AND EVALUATION SCHEME [Effective from the session : 2009-10]
Course: B.Pharm.

Year-I, Semester-I
S.N . Course Code PHARM111M PHARM111B PHARM112 PHARM113 PHARM114 PHARM115 PHARM116 PHARM111 P PHARM112P PHARM113 P PHARM114P PHARM115P Subject Name

Theory
Remedial Mathematics Or Remedial Biology Pharmaceutical Analysis-I Pharmaceutical Chemistry-I (Inorganic Pharm. Chem.) Pharmaceutics-I(General Pharmacy) Anatomy, Psysiology and Path physiology-I Professional Communication-I 1.

Period (Hours) L P 3 3 3 3 3 3 3 0 0 0 0 0 0 0

Sessional CT 15 10 15 15 15 15 15 TA 05 10 05 05 05 05 05 Tota l 20 20 20 20 20 20 20

Exam ESE 80 80 80 80 80 80 80

Subject Total 100 100 100 100 100 100 100

2. 3. 4. 5 6

Practical Day to Day Evaluation
7 8 9 10 11 Remedial Biology Pharmaceutical Analysis-I Pharmaceutical Chemistry-I (Inorganic Pharm. Chem.) Pharmaceutics-I(General Pharmacy) Anatomy, Physiology and Path physiology-I 0 0 0 0 0 18 4 4 4 4 4 20 ------------20 20 20 20 200 80 80 80 80 800 100 100 100 100 1000

T.A- Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE- Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively.                                    2     

 

 

 

 

 

 

 

 

 

U.P. TECHNICAL UNIVERSITY LUCKNOW
STUDY AND EVALUATION SCHEME [Effective from the session : 2009-10]
Course: B.Pharm.

Year-I, Semester-II
S.N . Course Code Subject Name Period (Hours) Sessional Exam Subject Total

Theory
1. 2. 3. 4. 5 PHARM121 PHARM122 PHARM123 PHARM124 PHARM125 PHARM121 P PHARM122P PHARM124 P Physical Chemistry Pharmaceutical Chemistry-II (Organic Chemistry-I) Anatomy, Physiology and Path physiology-II Computer Fundamentals & Programming Pharmaceutical Biostatistics

L 3 3 3 3 3

P 0 0 0 0 0

CT 15 15 15 15 15

TA 05 05 05 05 05

Tot al 20 20 20 20 20

ESE 80 80 80 80 80 100 100 100 100 100

Practical Day to Day Evaluation
6 7 8 Physical Chemistry Pharmaceutical Chemistry-II (Organic Chemistry-I) Computer Fundamentals & Programming 0 0 0 15 4 4 4 12 --------20 20 20 160 80 80 80 640 100 100 100 800

T.A- Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE- Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. 

             

3   

N.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2010-11] Course: B. 4.U. Physiology and Path physiology-III Pharmaceutics-II (Unit Operations-I) Pharmacognosy-I Pharmaceutical Chemistry-III (Organic Chemistry-II) Pharmaceutics-III (Community Pharmacy) Period (Hours) L P 3 3 3 3 3 3 --------------------- Sessional CT 15 15 15 15 15 15 TA 05 05 05 05 05 05 Total 20 20 20 20 20 20 Exam ESE 80 80 80 80 80 80 Subject Total 100 100 100 100 100 100 Practical Day to Day Evaluation 7 8 9 10 ------------18 4 4 4 4 16 --------------20 20 20 20 200 80 80 80 80 800 100 100 100 100 1000 T.                  4      .Pharm.P. 3. 2. Semester-III S. 1. Year-II.Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively.A. 5 6 Course Code PHARM231 PHARM232 PHARM233 PHARM234 PHARM235 PHARM236 PHARM231 P PHARM233P PHARM234 P PHARM235 P Subject Name Theory Pharmaceutics-II (Unit Operation-I) Pharmaceutical Jurisprudence & Ethics Pharmacognosy-I Pharmaceutical Chemistry-III (Organic Chemistry-II) Pharmaceuitics-III (Community Pharmacy) Anatomy.

Pharm. 4. Year-II. N. Physiology and Pathophysiology-IV Pharmaceutics-IV (Unit Operations-II) Pharmaceutical Microbiology Pharmacognosy-II Pharmaceutical Analysis-II Period (Hours) L P 3 3 3 3 3 -----------------Sessional CT 15 15 15 15 15 TA 05 05 05 05 05 Tot al 20 20 20 20 20 Exam ESE 80 80 80 80 80 100 100 100 100 100 Subject Total Practical Day to Day Evaluation 6 7 8 9 ------------15 4 4 4 4 16 --------------20 20 20 20 180 80 80 80 80 720 100 100 100 100 900 T. 3.                     5    .Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively.P. Semester-IV S.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE. 5 Course Code PHARM241 PHARM242 PHARM243 PHARM244 PHARM245 PHARM241 P PHARM242P PHARM243 P PHARM244 P Subject Name Theory Pharmaceutics-IV (Unit Operation-II) Pharmaceutical Microbiology Pharmacognosy-II Pharmaceutical Analysis-II Anatomy. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2010-11] Course: B.U. 2. 1.A.

TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2011-12] Course: B. Semester-V Period (Hours) L P 3 -----------------Sessional CT 15 15 15 15 15 TA 05 05 05 05 05 Tot al 20 20 20 20 20 Exam ESE 80 80 80 80 80 100 100 100 100 100 Subject Total Theory Pharmaceutical Chemistry-IV (Biochemistry) Pharmaceutics3 V(Pharmaceutical Technology-I) Pharmacology-I 3 Pharmaceutical ChemistryV(Medicinal Chemistry-I) Pharmaceutics-VI (Physical Pharmacy) Pharmaceutical Chemistry-IV (Biochemistry) Pharmaceutics-V (Pharmaceutical Technology-I) Pharmacology-I Pharmaceutical Chemistry-V (Medicinal Chemistry-I) Pharmaceutics-VI (Physical Pharmacy) 3 3 Practical Day to Day Evaluation 6 7 8 9 10 ----------------15 4 4 4 4 4 20 --------------------20 20 20 20 20 200 80 80 80 80 80 800 100 100 100 100 100 1000 T. 5 Course Code PHARM351 PHARM352 PHARM353 PHARM354 PHARM355 PHARM351 P PHARM352P PHARM353 P PHARM354 P PHARM355P Subject Name Year-III.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE. 1.P.         6    . S. N.U.A. 4.Pharm.Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. 3. 2.

Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE. N. Semester-VI S. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2011-12] Course: B. 2. 3.                                             7    . Year-III.P. 1.Pharm. 4.A.Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively. 5 6 Course Code PHARM361 PHARM362 PHARM363 PHARM364 PHARM365 PHARM366 PHARM361 P PHARM362P PHARM363 P PHARM364 P Subject Name Theory Pharmaceutical Chemistry-VI (Medicinal Chemistry-II) Pharmaceutics-VII (Pharmaceutical Technology-II) Pharmacology-II Pharmacognosy-III Professional Communication-II Environment & Ecology Period (Hours) L P 3 ---3 3 3 3 3 -----------------Sessional CT 15 15 15 15 15 15 TA 05 05 05 05 05 05 Total 20 20 20 20 20 20 Exam ESE 80 80 80 80 80 80 Subject Total 100 100 100 100 100 100 Practical Day to Day Evaluation 7 8 9 10 Pharmaceutical Chemistry-VI (Medicinal Chemistry-II) Pharmaceutics-VII (Pharmaceutical Technology-II) Pharmacology-II Pharmacognosy-III ------------4 4 4 4 ------------20 20 20 20 80 80 80 80 100 100 100 100 18 16 --200 800 1000 T.U.

Semester-VII S. 2.           8    .U. 1.Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively.P.A. N. 4. TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2012-13] Course: B.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE. 5 Course Code PHARM471 PHARM472 PHARM473 PHARM474 PHARM475 PHARM471 P PHARM472P PHARM473 P PHARM475 P PHARM476P Subject Name Theory Pharmaceutical Analysis-III PharmaceuticsVIII(Biopharmaceutics & Pharmacokinetics) Pharmacology-III Pharmaceutical Chemistry-VI (Medicinal Chemistry-III) Pharmacognosy-IV Period (Hours) L P 3 3 3 3 3 -----------------Sessional CT 15 15 15 15 15 TA 05 05 05 05 05 Tot al 20 20 20 20 20 Exam ESE 80 80 80 80 80 100 100 100 100 100 Subject Total Practical Day to Day Evaluation 6 7 8 9 10 Pharmaceutical Analysis-III Pharmaceutics-VIII (Biopharmaceutics & Pharmacokinetics) Pharmacology-III Pharmacognosy-IV Report on Industrial Visit 15 16 --180 ------------4 4 4 4 ------------20 20 20 20 80 80 80 80 100 820 100 100 100 100 100 1000 T. Year-IV. 3.Pharm.

Standardization of Herbal Drugs Or (B).Novel Drug Delivery Systems Or (G)-GMP.Pharmaceutical Packaging Or (F).P.Pharmaceutical Marketing Or (E). 3.Pharm.Standardization of Herbal Drugs Or (B).Clinical Pharmacy & Drug Interactions Or (D). Year-IV.Teacher Assessment ESE-End Semester Examination CT-Cumulative Test NOTE. 2. Semester-VIII S. 4. 1.Pharmaceutical Marketing Or (E).Duration in Theory & Practical of ESE shall be 3 (three) hours and 4 (four) hours respectively.Novel Drug Delivery Systems Or (G)-GMP. N.U. Quality Assurance & Validation Practical Day to Day Evaluation PHARMNatural Products 6 482 P PHARMProject on Elective:7 485P A).Clinical Pharmacy & Drug Interactions Or (D).Drug Design Or (C ).A. 5 Course Code PHARM481 PHARM482 PHARM483 PHARM484 PHARM485 Subject Name Theory Pharmaceutical Biotechnology Natural Products Pharmaceutical Industrial Management Hospital Pharmacy Period (Hours) L P 3 3 3 3 3 ------------------ Sessional CT 15 15 15 15 15 Exam Tot al 20 20 20 20 20 Subject Total 100 100 100 100 100 TA 05 05 05 05 05 ESE 80 80 80 80 80 Elective (A). Quality Assurance & Validation ------- 4 4 --- --- 20 20 80 80 100 100 15   8 -- -- 140 560 700 T.Drug Design Or (C ). TECHNICAL UNIVERSITY LUCKNOW STUDY AND EVALUATION SCHEME [Effective from the session : 2012-13] Course: B.Pharmaceutical Packaging Or (F). 9    .

Chain Rule. NCERT Publication Vol.. A textbook of Mathematics for XI-XII Students. straight line. 3. 3. Loney. I-IV. 2. Sultan Chand & Co. Definition and formulation of differential calculus.L “The elements of coordinate geometry” AITBS Publishers. S. locus of points. Rules of standard form of differential calculus. Sultan Chand and Co. Loney. S. Addition 2. Subtraction 3.P. Statistical Methods. area of triangle. Inverse of matrices Simultaneous equation by matrices. Limit and function 2. Multiplication 4. Trigonometric function of Integral calculus. Parametric rule. Unit-V: Linear differential equation of order greater than one with constant coefficient complimentary function. intercept form in normal. Trignometric ( sin/ cos ex ) BOOKS RECOMENDED 1. distance between two parts. 4. Unit-III: Differential Calculus1. Cramer’s Rule Algebra of matrics-1.L “Plane Trigonometry” AITBS Publishers. Narayan Shanti. and particular Integral (Xneax. Partial fraction of Integral 3. New Delhi 5. Gupta S. 10    . Unit-II: Certain co-ordinates. Integral calculus . Standard form of Integral calculus 2. 4.SEMESTER I PHARM-IIIM REMEDIAL MATHEMATICS Unit-I: Algebra: Equations reducible to quadratics. Unit-IV: 1.

Prasad Gorakh Text book on integral calculus . 9. Shyam. [08] Unit-III Morphology and histology of root. Shyamlal Charitable Trust. Allahabad. Basic concept of molecular biology (DNA. modification of stems and roots. fruit and seed. mites and silk worm. [08] Unit-II General structure and life history of insects like mosquito. Pothishala Pvt. ascaris. leaf.RNA) Unit-V Methods of classification of plants. Ltd. Allahabad. oxyuris and ancyclostoma.. 7. mitosis and meiosis. Patkar “ Comprehensive remedial mathematics”. Narayan Shanti. Ltd.6. Pothishala Pvt. New Delhi. trypanosoma. different types of plant tissues and their functions. [12] Unit-IV Plant cell: Its structure and non living inclusions. PHARM-IIIB REMEDIAL BIOLOGY THEORY Unit-I:General survey of Animal Kingdom.. Vishal Mehta. bark. Differential calculus .entamoeba. Prasad Gorakh Text book on differential calculus. Structure and life history of parasites as illustrated by amoeba. plasmodium. flower. stem. wood. schistosoma. “ Remedial Mathematics for Pharmacy’. 10. taenia. [04] [08] PHARM-IIIP 11    . house fly. 8.

3. Structure of human parasites and insects mentioned in theory with the help of specimens. common-ion effect.C. relative strengths of acids and bases. hydrolysis of salts. Care. 5. acid base indicators. Marshall & Williams “Text Book of Zoology” CBS Publishers & Distrubutors. New Delhi. HendersonHasselbach equation. mixed indicators. theory of indicators. Morphology of plant parts indicated in theory. use and type of microscopes. Morphology of plant parts indicated in theory. 2. Delhi. Fahn “Plant Anatomy” Aditya Books Private Limited. PHARM –112 PHARMACEUTICAL ANALYSIS-1 THEORY Unit-1 : Significance of quantitative analysis in quality control different techniques of analysis. polyprotic system. precision and accuracy. [06] Unit-II: Acid Base Titrations: Acid base concepts. methods of expressing concentration. neutralization curves. Dutta A. role of solvent. choice of indicators. Gross identification of slides of structures and life cycle of lower plants/animals mentioned in theory. microscopic examination of stem. Paul B “Laboratory Manual in Science of Biology” Mc Graw-hill book company. 6. primary and secondary standards. preliminaries and definitions. 4. Weiz. “ Botany for Degree students” Oxford. 4. ionization. [10] Unit-III: Oxidation reduction Titrations: 12    . 2. buffer solution.REMEDIAL BIOLOGY PRACTICAL PRACTICAL 1. Fundamentals of volumetric analysis. Note: There shall be no University Examination for Remedial Biology Practical. ionic product of water. law of mass action. root and leaf of monocot and dicot plants. Preparation. 3. pH. BOOKS RECOMMENDED 1.

some official assay procedures. potassium bromate. e. 3. supersaturation. Argentometric titrations and titrations involving ammonium or potassium thiocyanate. Oxidation Reduction Titrations : Preparation & standardization of some redox titrants e.Concepts of oxidation and reduction. and errors in weighing. solubility products. strengths and equivalent weights of oxidizing and reducing agents. solubility products. the colloidal state. Volhard’s method and Fajan’s method. theory of redox titrations. 2. iodine solution and ceric ammonium sulphate. effect of acids. post-precipitation. redox indicators. 1. filtration. [10] Unit-IV: Precipitation Titrations: Precipitation reactions. sodium thiosulphate etc. iodimetry and iodometry. Ignition. [08] [06] PHARM-II2P PHARMACEUTICAL ANALYSIS . temperature and solvent upon the solubility of precipitate. mercuric nitrate indicators. weights. Unit-V : Gravimetric Analysis: Precipitation techniques. Some exercises related to determinations of oxidizing & reducing agents. specific examples like barium as barium sulphate. filter papers and crucibles.1 PRACTICAL The students should be introduced to the main analytical tools through demonstration. should also be covered. oxidation reduction curves. thermogravimetric curves. potassium dichromate. Standardization of analytical weights and calibration of volumetric apparatus. The students should also be acquainted with the general apparatus requiring various analytical procedures. the requirements of a good balance. care & use of balance. methods of weighing. potassium bromate. potassium iodate. Gaylussac method. washing of the precipitate. boric acid. digestion. titrations involving ceric sulphate. organic precipitants. iodine. They should have a clear understanding of a typical analytical balance.g. potassium permanganate. Mohr’s method. some exercises related with determination of acids and bases separately or in mixture form. coprecipitation. Exercises involving potassium iodate. aluminium as aluminium oxide. potassium permanganate. 13    . Acid Base Titrations : Preparation and Standardization of acids and bases. redox reactions.g.

The Pharmacopoeia of India. Jeffery G. of the following classes of inorganic pharmaceuticals included in Indian Pharmacopoeia. Precipitation Titrations: Preparation and standardization of titrants like silver nitrate and Ammonium thiocyanate. talc. Her Majesty’s Stationary Office.Thomas M. Gravimetric Analysis : Preparation of gooch crucible for filtration and use of sintered glass crucible.. Iodine. An outline of methods of preparation. acids and bases (Sodium hydroxide.B. 3. Determination of water of hydration. if any..A. Conners K. 5.D. (1996) Gases and Vapors : Inhalants (Oxygen). 4. I&II. PHARM – 113 PHARMACEUTICAL CHEMISTRY-1 (INORGANIC PHARMACEUTICAL CHEMISTRY) Unit-I A.. Denny R. astringents(Zinc oxide. Pharmaceutical aids and necessities: water (purified water. Potassium permanganate. Mendhanm J. Wiley Inter-science. 2. lead. Pearson Education Asia. Povidone Iodine. Beckett. Anaesthetics( Nitrous oxide). Barnes J. CBS Publishers & Distributors 6. “Vogel’s Textbook of Quantitative Chemical Analysis”. water for injection and sterile water for injection). The Atherden Press of the University of London. Hydrogen peroxide. some exercise related to gravimetric analysis should be covered. Silver nitrate). limit test for iron. chloride & sulphate B. A. kaolin). Practical Pharmaceutical Chemistry. 5.C. 14    . tests of purity and identification and special tests. “Quantitative Analysis”. titrations according to Mohr’s. Topical Agents : Protectives (Calamine.. BOOKS RECOMMENDED : 1. uses. sources of impurities. Zinc Sulphate) and anti infectives (Boric Acid. British Pharmacopocia. pharmaceutical acceptable glass. Cambridge.. University Press.4. “A Text book of Pharmaceutical Analysis”.H. arsenic. phosphoric acid). Alexeyev V. Sources of impurities & their control.. heavy metals. and Stenlake. Volhards and Fajan’s methods.H. Vol. titanium dioxide. J.

Ferrous gluconate.hazards and precautions. Sb. Magnesium carbonate{ light and heavy}. Sodium dihydrogen phosphate. Ferrous sulphate. antioxidants (Sodium metabisulphite). Cr. clinical application and dosage. protective and adsorbents( Activated Charcoal. Sodium thiosulphate). sodium bicarbonate. Aluminium hydroxide. Light Kaolin. Calcium levulinate. standards and units of activity. To perform limit test of chloride. sodium chloride. Zn. Mn. Cationic and anionic components of inorganic drugs useful for systemic effects. S. measurement of activity. Co-ordination compounds and complexation. Unit-II:Gastrointestinal Agents : Acidifying agents (Dilute Hydrochloric acid). of Labs 5 15    . Electrolytes used for replacement therapy. magnesium chloride). [08] [08] [08] PHARM-113P PHARMACEUTICAL CHEMSITRY-I (INORGANIC PHARMACEUTICAL CHEMISTRY) List of Experiments 1. Calcium lactate. antacids(Bismuth subcarbonate.cellular electrolytes : Physiological ions. mineral supplements (Cu. methods of obtaining.study of such compounds used in therapy including poison antidotes(Calcium folinate. Aluminium sulphate Miscellaneous Agents: Expectorants (Ammonium chloride. nomenclature. Magnesium trisilicate ). acid-base balance & combination therapy( Calcium chloride. Magnesium hydroxide. Ferric Ammonium citrate).anti-caries agents (Sodium fluoride). Iron. [08] Unit-III : Major intra and extra. potassium chloride. Magnesium oxide{ light and heavy}. I). Heavy metal and No. Potassium Iodide). Iron and haematinics(Ferrous fumarate.Dental Products : Dentrifices. sulphate. Calcium gluconate. Calcium carbonate. cathartics ( disodium hydrogen phosphate. Unit-V Inorganic Radio-Pharmaceuticals: Nuclear radio pharmaceuticals. Magnesium sulphate and other Magnesium [08] compounds). Unit-IV : Essential and Trace Elements : Transition elements and their compounds of pharmaceutical importance. sodium acetate.

1 (GENERAL PHARMACY) Unit-I History of Pharmacy : Origin & development of pharmacy. Cosolvents. 2. J.H.al Modern Inorganic Pharmaceutical Chemistry. Preparation of following compounds:Boric acid Magnesium sulphate Heavy magnesium carbonate Calcium Carbonate Alum Zinc sulphate BOOKS RECOMMENDED : 1. 1996 edition. USP & International Pharmacopoeia. Lea & Febiger. introduction to pharmacopoeias with special reference to IP. sedimentation. laws & factors affecting energy requirements.A. Bentley and Drivers’ “Text Book of Pharmaceutical Chemistry”. surfactants antioxidants. Roche.et. [06] 16    [04] [03] . Unit-II Size Reduction : Definition.. study of hammer mill. Salt analysis 3. 2. C. T and Wilson. & their applications. Pharmacopoceia of India. London. waveland press. ball mill. Discher. 4. “Inorganic. Atherden L. principles. C. Soine. Medicinal & Pharmaceutical Chemistry”. preservatives. cyclone separator.Principles and laws Governing size reducts factors affecting size reduction. Pharmaceutical Additives : Colouring.. Oxford University Press.M.arsenic in the given sample. sieving. E. BP. 3. various methods & equipments employed for size separation e. scope of pharmacy. flavouring & sweetening agents. Block. fluid energy mill & disintegrator. 7 3 PHARM – 114 PHARMACEUTICS.g. for size reduction different methods of size reduction. elutriation methods..

Camphor Water BP 3. BP. Chloroform water BP 2. Lysol solution IP 2. proof spirit. USP/NF. digestion. liniments. Aromatic Elixirs USP/NF e) Spirits 1. inhalations and powders. maceration & their modifications. study of infusion. Unit-IV Extraction & Galenicals: Extraction processes. lotions. mouth washes. elixirs. solid-solid. a) Aromatic Waters 1. alligation. mixtures. calculation of doses for infants. adults and elderly patients. [07] [07] [10] PHARM-114P PHARMACEUTICS-I (GENERAL PHARMACY) I : Preparation of following classes of Pharmaceutical dosage forms (involving the use of calculations in metrology) as official in IP. [03] Introduction to Pharmaceutical Dosage Forms: A brief theory of : Solutions. Rose Water NF b) Solutions 1. Strong Ammonium Acetate solution BP c) Syrups 1. applications in the preparation of tinctures & extracts. Unit-V Mixing: Theory of mixing. decoction. mucilages. paints. spirits. alcohol dilution. percolation. aromatic waters.reducing recepercentage solutions. glycerins. Simple syrup BP/USP/IP d) Elixirs 1. pastes. syrups. Aromatic Ammonia spirit BP 17    .Unit-III : Pharmaceutical calculations : Posology. Factors affecting selection of extraction processes. Enlarging and reducing receipes. solid-liquid & liquid-liquid mixing equipments.

Liquorice liquid extract BP. ELBS Bailliere Tyndall. II: Experiments to illustrate principles of size reduction using Ball Mill. CBS Publishers. “Bentley’s Text Book of Pharmaceutics”. 18    1. Lea and Febiger. III: Experiments to illustrate mixing efficiency. ORS Powder IP 2.. Benzoin Inhalation BP . 5. 4.. Delhi.A. number of balls and time on the efficiency of ball mill.Liberman H. Decoction of Senna 3. 3. Delhi.. “Cooper and Gunn’s Tutorial Pharmacy”. British Pharmacopoeia.A and Kanig J.L. Starch Mucilage IP 1. CBS Publishers. New Delhi. 6. Absorbable dusting powder USP/N g) Lotions 1. Amino benzoic acid lotion BP h) Liniments 1. Calamine lotion IP 2. Compound benzoin tincture BP 4. Lachman L. Cooper and Gunn’s Dispensing for Pharmaceutical Students.J. Methyl salicylate liniment BP 2. “Theory and Practice of Industrial Pharmacy”. Effect of size of balls. Rawlins E. Turpentine liniment BP i) Mucilage j) Glycerins k) Inhalation l) Tinctures & Extracts 1. Kaolin Poultice BP 1. Carter S. Solid-Solid mixing. The Controller of Publications. Strong Ginger tincture BP 5. University Press. BOOKS RECOMMENDED: 1.f) Powders 1. Cambridge. Infusion of Tea 2. Her Majesty’s Stationary Office. Pharmacopoeia of India. 2.

Unit-V a) Concepts of health & disease: Disease causing agents & prevention of disease. Aulton. I & II. 9. Remington – “The science and practice of pharmacy” Vol. [08] Unit-II Skeletal system Structure. PHARM-115 ANATOMY PHYSIOLOGY & PATHOPHYSIOLOGY -I Unit –I a. 8. physiology of skeletal muscle contraction. Vol. muscle and nerve. Introduction to human body & organisation of human body. M. erythopoesis. Pennsylvania. Structural & functional characteristics of tissues. types of movements of joints. I & II. Unit-III Anatomy & physiology of skeletal & smooth muscle. specification for drinking water.epithelial. Mack Publishing Co. composition & functions of skeleton. muscle tone. Functional & structural characteristics of cell. b) Classification of food requirements : Balanced diet. connective.E. Nutritional deficiency disorders. c. types of muscle contraction. United States Pharmacopoeia (National Formulary).. Unit-IV Haemopoietic system : Composition & function of blood & its elements. neurotransmission.. b. blood coagulation.7. Detailed structure of cell membrance & physiology of transport process. their treatment & prevention. Classification of joints. energy metabolism. Churchill Livingstone. blood groups. Text Book of Pharmaceutics. [08] [08] [08] [08] 19    .

“Atlas of Normal Histology” – Lea & Febiger Philadelphia.C. Harper & Row Publishers. New Delhi. Parmar N. Oxford University Press. Pune. 4. Chatterjee C. R. Tenses. Churchill Livingstone.B. Niel. speech. 5. Active-Passive voice.C. D. Direct.A.S.PHARM-II5P HUMAN ANATOMY. Total leucocyte count. Pune Vidyarthi Griha Prakashan. 6. Preposition. WB Saunders Company. Guyton AC.. “Health Education & Community Pharmacy” CBS Publishers. 3.S. 8.H. Ranade VG. pulse rate and blood pressure.Indirect. Tortora GJ. Microscopic study of different tissues. and E. basic understanding of Electrocardiogram – PQRST waves and their significance. C. PHYSIOLOGY & PATHOPHYSIOLOGY -I PRACTICAL 1. 4. “Human Physiology”. 3. 9.R.C. Samson Wright’s Applied Physiology. Hall JE. Articles. PHARM-116 PROFESSIONAL COMMUNICATION-I UNIT-I English Grammar Parts of speech. Determination of bleeding time. Difore S. “Text book of Medical Physiology”. Keele. 2. Calcutta. & Anagnodokos NP “Principles of Anatomy & Physiology”. Medical Allied Agency. Count..L. Recording of body temperature. [12] 20    . 2. Estimationof haemoglobin in blood. clotting time. Shalya Subhash “Human Physiology” CBS Publishers & Distributors. Delhi. E and Joels N. “Text Book of Practical Physiology”. Ross & Wilson “Anatomy & Physiology in Health & Illness”. Study of human skeleton. BOOKS RECOMMENDED: 1. 7.

C and Martin H. Importance of non-verbal communication. Robbins. UNIT-V Personality types. pauses. Précis and Essay writing Comprehension Speed reading. Chand & Co. non words. Decision making Motivation Attitude Thinking [06] [06] [08] [08] BOOKS RECOMMENDED 1. “High School Grammar and Composition”. UNIT-III Working on accent neutralisation.Tips. UNIT-IV Presentation techniques.UNIT-II Letter writing. scanning & swimming. eye contact for small & large groups. Wren P. S “Organisational Behaviour” 21    . 2. S. stresses. Role plays. .. debates. voice modulation.

theory of strong elecrolytes (Debye Huckle theory). theory of buffers. Chemical kinetics : Zero. Kohlrausch law. pH : determination of PH buffers. 7. Bomb calorimeter. Langmuir theory of adsorption. dipole moment) and chemical constituents. colligative properties. Arrhenius theory. 3. Unit-V 10. crystal diffraction. Thermo chemistry : Definition & conventions. molar & equivalent conductivity and its variation with dilution. degree of freedom. heat of solution. Solutions : Ideal and real solutions. Joule-Thompson’s effect. first and second order reaction. 11. heat of reaction. [08] [08] [08] 22    . heat of formation. optical rotation. Hess law of constant summation. parachor. phase rule (excluding derivation). first. complex reactions. Electro chemistry : Faraday’s laws of Electrolysis. Behaviour of gases : Kinetic theory of gases. Electric conductance & its measurement. 5. deviation from ideal behaviour and explanation. Unit-III 6. degree of ionisation & Ostwald dilution law. viscosity. Amorphous and crystalline solids : geometry & symmetry of crystals. heat of neutralisation. bond energies. types of crystals. component. The liquid state : Physical properties (surface tension.SEMESTER-II PHARM-121 PHYSICAL CHEMISTRY Unit-I 1. third and zeroth law. Thermodynamics : Fundamentals. 8. Physical properties of crystals. Transport number & migration of ion. Phase equilibria : Phase. Hittorfs theoretical device. Kirchoffs equation. rheochor. elementary idea of reaction kinetics. heat of combustion. Adsorption : Freurdlich and Gibbs adsorption Isotherms. 2. characteristics of homogenous and heterogeneous catalysis. solutions of gases in liquids. Millers indices. [08] Unit-IV 9. Unit-II 4. acid base and enzyme catalysis. absolute temperature scale. refractive index. second.

8. Experiments of Physical Chemistry. and Prabartak.D. Glasstone S. Atkins P & Paula.I) Unit-I Structure and Properties : Atomic Structure.D. 2. Determination of rate constant of simple reaction. BOOKS RECOMMENDED: 1. Shoemaker.S. Determination of surface tension. C. 6. [08] PHARM-I2IP PHYSICAL CHEMISTRY PRACTICAL 1. sulphur. 3. D. verify Ostwald dilution law and perform conductometric titrations. 4.. J.R. Pali S. Garland. pH determination by different methods.Cooling curves & Phase diagrams for one & two component system involving eutectics. 9.S. PHARM-122 PHARMACEUTICAL CHEMISTRY-II (ORGANIC CHEMISTRY. “Atkins Physical Chemistry” Oxford University Press. Practical Physical Chemistry. Tuli G. & Lewis D. 23    . Bahl B. 4. 6. Chand & Co. MC Graw Hill Book Co. Determination of solubility. Haltone Limited. Distribution law & application to solvent extraction.D. atomic orbital. 2..E. 5. NaCI-H2O system). 7. Determination of partition co-efficient.. & Bahl Arun. Macmillan Education. Calcutta. Negi A.C. KI-H2O. Elements of Physical Chemistry.K.“Textbook of Physical Chemistry” Wiley Eastern Ltd. 5. molecular orbital. 3. Determination of specific rotation of sucrose at various concentrations and determine the intrinsic rotation. hybridization.. Determination of viscosity. & Anand S. Determination refractive index of given liquids. Determination of cell constant.P. congruent & incongruent melting point (examples-water. S.W. S. Essential of Physical Chemistry.

3. Synthesis of following compounds Picric acid Aniline Acetanilide Aspirin Hippuric acid 24    6 4 5 . Unit-II Isomerism. amines (aliphatic & aromatic). structure of benzene. Stereochemistry including optical activity. bromination. di & tricarboxylic acids. chloroform. arenes. acetone and preparation of absolute alcohol. specification of configuration and conformational analysis. organolithium compounds. Alcohols. stereoisomerism. Classification & Nomenclature of organic compounds. geometrical isomerism. resonance. acetylation. Unit-III Important methods of preparation. free radical substitution reaction. Identification of elements and functional groups in given sample. Purification of solvents like Benzene. reduction & oxidation. 2. covalent. alkenes. reactions with special reference to mechanism of the following classes of compounds: Alkanes. Organometallic Compounds. electrovalent and co-ordinate bond. orientation of aromatic substitution. alkynes & dienes. aryl halides. carboxylic acids & their derivatives. Unit-IV Aromatic Compounds. [08] [08] [08] [08] [08] PHARM-I22P PHARMACEUTICAL CHEMISTRY –II (ORGANIC CHEMISTRY-I) SUGGESTED LIST OF PRACTICALS 1. inductive effect. Unit-V Aldehydes and ketones (aliphatic & aromatic). phenols.sigma & Pi bond.Grignard reagent. Synthesis of compounds involving benzoylation. resonance. their preparation &synthetic application. hydroxy acids. aromatic character. alkyI halides.

PHYSIOLOGY & PATHOPHYSIOLOGY-II Unit-I : Central Nervous System : Functions of different parts of brain and spinal cord. Neurohumoral transmission in the central nervous system. taste buds.. Mechanism of neurohumoral transmission the A. Cranial nerves and their functions. burns. 3. 5. electroencephalogram. 60 B. Unit-IV : . [07] [06] [05] Unit-III : Lymphatic System : Composition . First Aid : Emergency treatment of shock. E. Hendrikson. nose (smell). 6. Organic Chemistry. R. Unit-II : Sense Organs : Basic anatomy and physiology of the eye (vision).. Textbook of Practical Organic Chemistry. F.S. specialized functions of the brain. poisoning. snake bites. Bunglaw Road. and spleen.N.K. Jain. 2. Demography and Family Planning. and Boyd R.. PHARM-123 ANATOMY. I. Organic Chemistry..G. formation and circulation of lymphs. Delhi. Finar. New Delhi. & Saunders.C. ELBS/Longman. [06] [04] Autonomic Nervous System : Physiology and functions of the autonomic nervous system.L. and skin (superficial receptors). 7. I & II. Practical Organic Chemistry.W. Mann. Organic Chemistry.T. Ltd. Morrison. Organic Chemistry.P-Bromo acetanilide Iodoform Oxalic Acid BOOKS RECOMMENDED: 1. lymph node 25    . 4.N. fractures and resuscitation methods. ear (hearing). Sohan Lal Nagin Chand & Co. reflex action.” Organic reactions Stereochemistry & Mechanism". Prentice Hall of India Pvt. 8. Medical termination of pregnancy. ELBS/Longman. ELBS/ Longman. Godly..I.Kalsi. “ Naming organic compounds”. B. Vol. Vogel A. M.

Human Physiology. Computer code. Oxford University Press. Pune Vidyarthi Griha Prakashan. and AIDS). filariasis. rabies. 8. & Anagnodokos NP. Storage devices. Various window features. Text book of Medical Physiology. C. Difore SH. tetanus. Time sharing and Real Time System. Internetworking: Bridges. MAN. Pune. 3. Chatterjee C.S. WAN. Health Education & Community Pharmacy CBS Publishers. Internet. syphillis. CBS Publishers & Distributors.A. Repeaters and Routers. computer classification of Boolean algebra. Evolution of operating system.. Churchill Livingstone. modes of transmission and prevention (Chicken pox. whooping cough. diphtheria. Delhi.Interactive. 9. network topology. 2. 5. WB Saunders Company. poliomyelities. 4. Harper & Rave Publishers.Unit-V Communicable Diseases : Brief outline. LAN. 7. influenza.. Text Book of Practical Physiology. Hall JE. Ranade VG. Parmar N. Principles of Anatomy & Physiology. Single User Operating System and Multi-user Operating system. Compare MS-DOS vs. 6. Shalya Subhash. trachoma. Anatomy & Physiology in Health & Illness. measles. Computer Organization. Internal and External commands in MS-DOS. gonorrhoea. Guyton AC.. Samson Wright’s Applied Physiology. Overview of Computer Networks. UNIX. helminthiasis. tuberculosis. Medical Allied Agency. Computer Software. Batch. [12] PHARM-124 COMPUTER FUNDAMENTALS AND PROGRAMMING Unit-1:Definition and Overview of Computer. Keele. Ross & Wilson. Unit-2: Introduction: Operating system and function. Calcutta. Tortora GJ. Human Physiology. Intranet. Types of software. Input Devices Out put devices. malaria. E and Joels N. 26    . their causative agents. New Delhi. Niel. BOOKS RECOMMENDED: 1. Computer classification. leprosy.C. “Atlas of Normal Histology” Lea & Febiger Philadelphia.

N. Computer Fundamentals. PHARM-124P Computer Fundamentals and Programming Software Lab to be used for the following:1. formatting table handling. main components of Access tables. 4. Browser etc. uses of Internet in Pharmaceutical Industry BOOKS RECOMMENDED: 1. Excel-2003. Windows. Computer Programming in ‘C’.5: Computer applications in Pharmaceutical and clinical studies. PHI Publication.K.” Computer fundamentals with Pharmacy Applications”. 3. concept of Four P’s (Planning . Managing Windows. Introduiction to MS-Access 2003. working on Query and use of database. Unit. Raja Raman.Histogram.3: Introduction to MS-OFFICE-2003.Tiwari. Working with Disk . 4. Circular diagranm) Classification and Tabulation of data. saving slides show controls.Unit. ways of delivering Presentation. Editing.Rao. word 2003 Document creation. animation and multimedia effects. Preparation. Method of collective data Diagramatic representation of data (Pie. Sampling-Types of sampling 27    . R. “ Biostatistics & computer Applications”.) PHARM-125 Pharmaceutical Biostatistics Unit-I 1. MS Access). Computer Operating System Like DOS and Windows.K. Database language. 4.g. Editing. 2. BPB Publications.. Data models schema and instance . Elements of Power point . MS Power point. G. Bar. short cut keys used in EXCEL. 2. Unit 4: MS-Power point 2003-Job Profile. Reports. Practice and Presentation) ways of handeling presentations e. Forms table handeling.N. Important functions. 3. 3. Internet Features (E-mail. working Retrieval. creating. Sinha. Hunt N and Shelley J. MS Excel. “Computers and Common Sense” Prentice Hall of India. mail merge. Adding formatting. Folders and files. 5. V. MS-Office 2003 (MS Word. 2. Queries. Database system concepts.

Boltan’s Pharmaceutical Statistics.Y. Greval B. Statistical Methods. Unit-II. Gupta S. A textbook of Mathematics for XI-XII Students. Mean. Median c. 4. New Delhi. Quartile deviation b.S.Measure of central tendency for decrete and continuous data.one way and two way classification.1.Fit of Poisson 4. Practical and Clinical Application. Normal distribution –Fit of Normal BOOKS RECOMMENDED 1. Mean deviation c. Testy.Merits and limitations of sampling Sampling errors and non sampling errors.Simple Probability Addition Probabilty Multiplication Probabilitty 2. Method of least square in straight line Unit-IV-Statistical Inferences. Sultan Chand and Co. 2. Binomial distribution. NCERT Publication Vol.t-test z-test X2 –test F. Correlation and regression analysis c. a. New Delhi..” Biostatistics for Pharmacy”.Confidence (feucidial ) limit. Higher Engineering Mathematics. 3. ModeMeasure of dispersion a. Standard error of Mean (SEM) Unit-IIIa. Theory of Probability. b. Poisson distribution. N. Khanum.P. 5.Fit of Binomial 3. Marcel Dekker.Hypothesis. Srewness and Kurtosis b. Types of means. Nonlin (ANOVA) Unit-V. Khan. Khanna Publication.. I-IV. 28    .test ( variance ratio) Analysis of variances.

habit. corrosion. manometers and measurement of flow and pressure. Unit Operations : Introduction. basic situations of fluid flow. Industrial Hazards and Safety Precautions : Mechanical. Unit-III 5. forms size and factors affecting them. shape. Ventilation & AC Systems: Basic concepts and definition. flow meters. circulating magma and Krystal crystallizer. Accident record. rotary filter. Industrial dermititis. Heating. Tanks. Nucleation mechanisms. purified water. Supersaturation theory and its limitations. Material of Construction : General study of composition. industrial centrifugal filters. agitated batch. Filtration and Centrifugation : Theory of filtration. UNIT – IV 6. soft water. Psychrometric chart and measurement of humidity. filter aids. Single vacuum. cleaning and standardisation of cleaning. Study of various types of Crystallizer. wet bulb and adiabatic saturation temperatures. and centrifugal sedimenters. equipment for dehumidification operations. Principles and applications of refrigeration and air conditioning. size. industrial filters including filter press. washing. Properties and applications of the materials of construction with special reference to stainless steel and glass. edge filter. Material and heat balances around Swenson Walker Crystallizer. 4. application of humidity measurement in pharmacy. Concept of boundary layer. [06] 29    [10] [08] [08] . Electrical. Unit-V 7. valves. Factors affecting filtration.SEMESTER-III PHARM-231 PHARMACEUTICS-II (UNIT OPERATIONS-I) Unit-I 1. Swenson Walker. Reynold’s number. Viscosity. Caking of crystals and its prevention. resistance. geometry. Crystallization : Characteristics of crystals like-purity. basic laws. Solubility curves and calculation of yields. filter media. 8. Chemical. water for injection . 2. quality requirement and treatment of water. Water systems – Raw water. crystal growth. fire and dust hazards. Fluid Flow : Types of flow. Principles of centrifugation. Unit-II 3.

4.L. Introduction to Chemical Engineering Mc Graw Hill International Book Co. New Age Publishers. BOOKS RECOMMENDED 1.PHARM-231P PHARMACEUTICS-II (UNIT OPERATIONS-I) PRACTICAL 1.H. Unit Operation of Chemical Engineering Mc Graw Hill International Book Co. Mc Graw Kogakusha Ltd.C. Perry R. 6. Measurement of rate of flow of fluids and pressure by: a) Simple and differential manometers b) Venturimeter c) Orifice meter 2. 3.H. and Banchero J.L. Gavhane. Nirali Prakashan. and Smith J. Determination of dry bulb and wet bulb temperatures and use of Psychrometric charts. “Unit Opeation-I”. Pharmaceutical Engineering. 4. K. London. 5. McCabe W.. 5.T. Sambhamurthy. 30    . Determination of Reynold Number. Badger W. 2.. b) Solid – liquid separation and stability of suspension. 3. & Chilton C. Study of characteristics of crystals 7.A. Study principle of centrifugation for a) Liquid –Liquid separation and stability of emulsions. Study of solubility curve of crystals. Study of factors affecting rate of filtration a) Effect of different filter media b) Effect of viscosity of filtrate c) Effect of pressure d) Effect of thickness of cake e) Effect of filter aids. Chemical Engineers Handbook. London.

4. 2. (E) States Shops & Establishments Act & Rules. Mittal. N. 2.T. Pharmaceutical Education – A brief review. Singh. Pharmaceutical Ethics: Unit-II : An elaborate study of the following: (A) Pharmacy Act 1948 (B) Drugs and Cosmetics Act 1940 and Rules 1945 [14] Unit-III : (C) Medicinal & Toilet preparations (Excise duties Act 1955) (D) Narcotic Drugs & Psychotropic Substances Act 1985 & Rules.M.-I. Delhi. [07] [05] [08] [06] Unit-IV : A brief study of the following with special reference to the main provisions. National Book Centre. Relevant Acts & Rules Published by the Govt.C.PHARM-232 PHARMACEUTICAL JURISPRUDENCE & ETHICS Unit-1 : Introduction 1. II & III” Vallabh Prakashan. (A) Poisons Act 1919 (B) Drugs and Magic remedies (Objectionable Advertisements) Act 1954. 31    .Vol. Harkishan “History of Pharmacy in India. A Textbook of Forensic Pharmacy. (E) Drugs Price Control Order 1995.E. B.I. of India.S Food and Federal D&C Act Note : The teaching of all the above Acts should cover the latest amendments. Dr. Pharmaceutical Legislations – A brief review. Sundari Mohan Avenue. (C) Medical termination of Pregnancy Act 1970 & Rules 1975. Vallabh Prakashan. BOOKS RECOMMENDED : 1. Act 1987 (G) Patents Act 1970 (H) Weight and Measures Act (I) Package and Commodity Act (J) U. Calcutta. 3. Textbook of Forensic Pharmacy. N. Jain.K. Unit-V : (F) A. (D) Prevention of Cruelty to Animals Act 1961.. 3. Drugs & Pharmaceutical Industry – A brief review. 4.

E.PHARM-233 PHARMACOGNOSY – I Unit-I : Definition history. Honey. Mutation & hybridization with reference to medicinal plants. Umbelliferae. acacia. Classification of Drugs : Alphabetical. Leguminosae. shark liver oil. microscopic. Marine pharmacognosy. [08] [02] [02] [01] [02] [04] [02] [04] 1. Lard & Suet. chemical & pharmacological. D. Processing & Storage of crude drugs : A. Collection. WHO guidelines for standardisation of medicinal plants. Factors influencing cultivation of medicinal plants. hydnocarpus oil. Papaveraceae. marine. B. Unit-V : 6. wool fat. Plant taxonomy : Study of following families with special reference to medicinally important plants – Apocynacae. Unit-III : 4. scope & development of Pharmacognosy. Plant hormones and their applications. Poly Houses/ Green Houses for cultivation. Novel medicinal agents from marine sources. Cultivation. taxonomical. Pest & Pest Management . Labitae. sterculia & tragacanth. Kokum butter. [02] Unit-II : 3. Unit-IV : 5. Cocabutter. Source of Drug : Biological. Morphological. physical. starch. Polyploidy. Acanthaceae. Rice-bran oil. castor oil. Quality Control of crude drugs : Adulteration of crude drugs and their detection by organoleptic. Guar gum. Rutaceae. Codliver oil. 32    . Linseed oil. mineral and plant tissue cultures as source of drugs. Type of Soils & fertilizers of common use.natural pest control agents. Systematic pharmacognostic study of following : a) Carbohydrates & derived products : Agar. Solanaceae. Rubiaceae. Isabgol. C. Liliaceae. pectin. 2. Compositae. [07] [08] b) Lipids – Beeswax. chemical and biological methods of evaluation including Quantitative microscopy.

Study of Plants belonging to family Liliacae 4. Determination of vein-islet and vein termination number. Starch and Honey. 9. Sterulia and Tragacanth. Vein determination number and palisade ratio. BOOKS RECOMMENDED 1. Study of various types of phloem fibres. Calcium oxalate Crystals & Phloem Fibres. Senna. Preparation of herbarium sheets. Acacia. “Pharmacognosy” Bailleire Tindall East bourne. 4. Microscopical measurements of starch grains (Wheat. Shark-liver oil and Linseed oil. 14. 3. 5. Microscopical Measurements of cell & cell contents Starch grains. c) Average weight of Ispaghula husk. 6. 13.. Study of Plants belonging to family Umbilliferae. Physical characteristics of Caster oil. Study of Plants belonging to family Rutacae. 3. Identification of crude drugs belonging to carbohydrates & lipids. & Evans. 5. their study and microscopical measurements (Rhubarb. 2. Vein islet number. Stomatal number. W. Cod-liver oil. 12. Determination of palisade ratio. Study of Plants belonging to family Solanacae. G. a) Chemical tests of Pectin. Trease. Maize).I PRACTICAL 1. Various types of calcium-oxalate crystals. 11.E. SUGGESTED PRACTICALS 1. 33    . 10.) 8. Morphological characteristics of plant families mentioned in theory. Potato). Determination of leaf Constants such as Stomatal index. Chemical Tests of Agar. 2. 7. b) Swelling factor of Isapaghula husk. U. Determination of stomatal number with the help of camera lucida along with the working of instrument. Determination of stomatal index. Liquorice etc. Microscopical measurements of starch grains (Rice.K.C.PHARM-233P PHARMACOGNOSY . 15.

II : Heterocyclic Compound – Nomenclature. fats and waxes.A. Michel. Bechmann rearrangement. 7. thiazole. pyrimidine. indole. thiophene. 5. structure elucidation. Verley reduction. Wallis T. Knoevanegal reaction. reactions.2. 8. Benzoin condensation. structure. Unit . London. “Marine Natural products”. lactose and maltose. anthracene and phenantherene.. Diel’s alder reaction. Structure of Nucleic Acids. iii) Polysaccharides – Starch. phenothiazines. pyridine. [08] Unit-IV: Classification. properties and pharmaceutical importance of pyrrole. Schewer PJ. preparation. Chemistry & identification of oils. Analytical Microscopy. [08] [08] Unit-V : Classification. identification. cycloaddition. benzimidazole. Compounds containing active methylene group and their synthetic importance. Reformatsky.Bristol.E. Polymers and polymerisation.. J. [08] Unit-III : Name reactions – Definition.III (ORGANIC CHEMISTRY -II) Unit-I : ά. “ Pharmacognosy & Phytochemistry”. Wallis. β.R. Mannich reaction. Scientechnica. London.E. furan. Chemistry. T. Mohammed Ali. Wright. Text book of Pharmacognosy. ii) Disaccharides – Sucrose. pyrazole. J&A Churchill Limited. acids and proteins.Unsaturated carbonyl compounds. imidazole. Ltd 4. Brain K. Churchill. Polynuclear hydrocarbons-Napthalene.Acetoacetic ester and malonic ester. PHARM-234 PHARMACEUTICAL CHEMISTRY . general methods of preparation and reactions of amino [08] 34    . “The Practical Evaluation of Phyto Pharmaceutical”. reaction mechanism and synthetic application of Merwin –Pondorff. identification of : a) Carbohydrates i) Monosaccharides – Glucose and fructose. Oppeneaur oxidation. Academic press. and Turner T D.

PHARM-235 PHARMACEUTICS – III (COMMUNITY PHARMACY) Unit-I 1. Materials. 6.. R. fats and waxes.PHARM-234P PHARMACEUTICAL CHEMISTRY-III (ORGANIC CHEMISTRY-II) PRACTICAL 1. 2. M. Morrison. 3. The ELBS/ Longman. Jain. Space layout.. code of Ethics. Prescriptions. Definition. ELBS/ Longman. Finar.” Organic Reactions Stereochemistry & Mechanism”.K. Organic Chemistry.C. Shoban Lal Nagin Chand & Co. Vogel’s Textbook of Practical Organic Chemistry. Kalsi. Mann P G & Saunders B C. 4. London.R. legality & identification of medication related problems like 35    [06] . Prentice Hall of India. and Boyd. sap value. Determination of Iodine value . Community Pharmacy Management i) Selection of site. scope of community pharmacy Roles and responsibilities of Community pharmacist. Acid value. Furniss B S. Organic Chemistry Vol. 5. ELBS/Longman. T. and design ii) Staff. BOOKS RECOMMENDED 1. London. Identification of organic compounds and their mixture with derivatization. Organic Chemistry. New Delhi. Practical Organic Chemistry.. stocking iii) Legal requirements iv) Maintenane of various registers v) Use of Computers Unit-II 3. Ester value of oils. Hannaford A J. I & II. 2.coding.N. Private Limited. I. 2. Synthesis of Organic Compounds involving two steps.parts of prescription. Delhi. and Sharma S. Smith P W G and Tatehell A R. 3.L.

OTC Medication. ABC. Strategies to overcome barriers Patient information leaflets. design.drug interactions incompatibility. & layouts.Definition. OTC medication list & Counseling Unit-V 10. Patient compliance Definition. methods for screening Blood pressure/ blood sugar/ lung function And Cholesterol testing. prevention of communicable diseases. 4. VED. pregnant & breast feeding women. Health screening services Definition. Role of Pharmacist in family planning. various methods of Inventory Control. Rational drug therapy – Brief introduction [10] [06] [10] [08] 36    . Communication skills and Patient counselling Need for good communication. Unit-IV 8. Health Education WHO Definition of health. safety stock Unit-III 5. importance. Definition. Factors affecting compliance. Inventory control in community pharmacy. and geriatric patients. Pharmacoepidemiology & Pharmacoeconomics – Brief introduction 12. role of pharmacist in improving the compliance. 9. Lead time. care for children. EOQ. 11. and health promotion. advisory labels 7. Pharmaceutical care Definition and Principles of Pharmaceutical care.content. nutrition. Key communication skills. 6.

Cooper and Gunn’s Tutorial Pharmacy. CBS Publishers.. Carter S. B. 3. Cooper and Gunn’s Dispensing for Pharmaceutical Students. Govt of India Publication. Community Pharmacy & Health Education.P. Health screening services and study of equipments for:Blood glucose determination (Glucometer) Blood pressure (BP apparatues) Lung function test (Peak flow meter) 5.J. Remington Pharmaceutical Sciences. Cambridge. K. Pennslyvannia.P. 8. Drugs & Cosmetics Act & Rules. Delhi.J. 4. Ansel H. Her Majesty’s Stationary Office. Interpretation of various pathological report of blood and urine.E. 5. 4. Mack Publishing Co. Bombay. 9..C. Prescription handling and identification of drug interactions. I. 6. CBS Publishers.PHARM-235P PHARMACEUTICS – III (COMMUNITY PHARMACY) PRACTICAL 1. Varghese & Co. Delhi. Pharmaceutics – The Science of Dosage Form Design.S.. 3. 6. incompatibilities. Parmar N. Carter S. Aulton M. Introduction to Pharmaceutical Dosage Forms. 2. 37    .. 7. Study of OTC medications List & Available brands 7.. 2. Categorization and storage of Pharmaceutical products bases on legal requirements of labeling and storage. Project report on visit to the nearby Community for Counseling on the rational use of drugs and aspects of health care. BOOKS RECOMMENDED : 1.M. Design of community pharmacy to incorporate all pharmaceutical care services (as per schedule N). ELBS/ Churchil Livingstone.. CBS Publishers.

Cirrhosis of liver. Robbins SL.PHARM -236 ANATOMY. Keele. Ulcerative colitis.. Zollinger. Guyton AC. Shalya Subhash.. WB Saunders Company. 38    . pancreatitis. metaplasia. physiology of urine formation. Hall JE. 8. 2.A.. CBS Publishers & Distributors. Pharmacotherapy – A Pathophysiological Approach. 5. Text book of Medical Physiology. [06] Unit-III – Urinary System – Anatomy & physiology of urinary system. BOOKS RECOMMENDED 1.S. 7. & dysplasia. E and Joels N. Elsevier. Ross & Wilson. Cellular AS daptation. migration of WBC’s mediaters of inflammation. Harper & Rave Publishers. Parmar N. Amoebiasis. Medical Allied Agency. Principles of Anatomy & Physiology. Human Physiology. & Anagnodokos NP. Calcutta. pathophysiology of renal feature. 4. glomerulonephiritis. Regional & Applied Part I.D. Dipiro JL. Chaurasia B. Hepatitis.Basic mechanisms involved in the process of inflammation and repair Alterations in vascular permeability and blood flow. Urinary tract infection. [08] Unit-IV-Cell injury & Adaption-Courses of cell injury. PHYSIOLOGY AND PATHOPHYSIOLOGY – III Unit I – Digestive system –Parts of digestive system. Niel.C. intracellular accumulation & pathophysiology of Neoplasm. Oxford University Press. pathogenesis & morphology of cell injury. 9. Tortora GJ. Churchill Livingstone. Kumar V. typhoid. Various gastrointestinal secretions & their role. aplasia. Health Education & Community Pharmacy CBS Publishers.Ellison syndrome. [08] Unit II –Pathology of disorders related to digestive system Peptic Ulcer. 6. Difore SH. Human Anatomy. Human Physiology. “Atlas of Normal Histology” Lea & Febiger Philadelphia. Brief outline of the process of repair. acid. WB Saunders. 10. New Delhi. Anatomy & Physiology in Health & Illness. Delhi.Atropy. Crohns disease. Unit-V. their structure and functions. New Delhi. 11. Chatterjee C. Samson Wright’s Applied Physiology. hypertrophy.base balance. 3. Basic Pathology. CBS Publishers & Distributors. C. II & III.

Elements of computer aided manufacturing (CAM) . simple steam and flash [08] PHARM-241P PHARMACEUTICS-IV (UNIT OPERATIONS-II) PRACTICAL 1. flow level and vacuum and their measurements. [08] [08] Unit –IV : Drying : Moisture content and mechanism of drying . Reactors and fundamentals of reactor design for chemical reactions. drying calculations. gas laws. primary and secondary quantities. factor affecting evaporation. volatility. rate of drying and time of [08] Unit -III : Distillation : Raoult’ s law . Determination of overall heat transfer coefficient. dryers used in pharmaceutical industries – Tray dryer. Azeotropic and extractive distillation . dimensionless groups. dimensionless formulae. film evaporators. steady and unsteady states. spray dryer and special drying methods. [08] Unit-V : Automated Process Control Systems : Process variables. rate process. tie substance.SEMESTER IV PHARM-241 PHARMACEUTICS – IV (UNIT OPERATIONS – II) Unit-I : Stoichiometry : Unit proceses material and energy balances. . Study of factors affecting rate of evaporation :a) Effect of surface area b) Effect of temperature 39    . mole volume. principles of rectification. dimensionless equations. molecular units. pressure. different types of graphic representation. classification and type of dryers . Fluidized bed dryer. temperature. single effect and multiple evaporator. mole fraction. Mccabe thiele method for the calculations of number of theoretical plates. Unit-II : Evaporation : Basic concepts of phase equilibria. Elements of automatic process control and introduction to automatic process control systems. evaporator. distillations . Phase Diagrams . 2. equilibrium state.

Nutrition. Badger W. Unit-II : 4. Introduction to Chemical Engineering Mc Graw Hill International Book Co. 2. “Unit Operation-II”. Introduction to the scope of microbiology.. 5. and Smith J. Identification of Microbes : Stains and types of staining techniques. Unit Operation of Chemical Engineering Mc Graw Hill International Book Co. PHARM-242 PHARMACEUTICAL MICROBIOLOGY Unit-I : 1.3. Study of factors affecting rate of drying a) Surface area b) Temperature 4. Gavhane. New Age Publishers. 5. 3.L. London.C.. Structure of bacterial cell. K. [08] 40    [08] . Chemical Engineers Handbook. & Chilton C.T.H. 4. Elementary knowledge of engineering drawing Alphabets/ letter writing Scales Orthographic projections – First and third angle projection methods Simple Isometric views BOOKS RECOMMENDED : 1. Sambhamurthi Pharmaceutical Engineering. 5. Determination of rate of drying. 2. Perry R. Mc Graw Kogakusha Ltd. London. electron microscopy.A.H. Nirali Prakashan.L. Experiments based on a) Steam distillation b) Extractive distillation c) Azeotropic distillation 6. 3. and Banchero J. free moisture content and bound moisture content. cultivation & isolation of bacteria & viruses. McCabe W. Classification of microbes and their taxonomy: Bacteria and viruses.

Disinfection. evaluation of antiseptics and disinfectants. 41    . fungus and yeast. Study of sterilization methods & equipments • • Dry heat Moist heat 2. Preparation of various types of culture media. B.clean and aseptic area. microbial assay of antibiotics and vitamins.Unit-III : 6.P. nosocomial infection. 8. vitamin B12. Preservative efficacy Unit-V : 9. [08] Unit-IV : 7. control of hospital infections. validation of sterilization methods & equipments. validation of sterilization techniques. PHARM-242P PHARMACEUTICAL MICROBIOLOGY PRACTICAL Experiments devised to prepare various types of culture media. A. yeast. Sterilization. dynamics of disinfection. 5. sub-culturing of common aerobic and anaerobic bacteria. Isolation of bacteria. SUGGESTED PRACTICALS 1.control of microbial contamination during manufacture. fungi. testing the sterility of pharmaceutical products as per I. various methods of isolation and identification of microbes. various staining methods. manufacture of sterile products. sterilization techniques and their validation. different methods. 3.P. disinfectants And antiseptics and their evaluation. Sterility testing as per I. 4. factors influencing disinfectants. Microbial assays of antibiotics. requirements. Sub-culturing of common bacteria. 10. Identification and staining of bacteria. Control of microbes by physical and chemical methods. Factory and hospital hygiene.

Benzoin.R. Clove. Black pepper. Chenopodium. Stanier R. Gunasekaran P. Wheelis M. Lemon peel. William & Wilkins. Eisen Microbiology. Nutmeg. 4. Prescott L. Palmarosa. 5.P. Jatamansi.• • • • • Simple staining Gram staining Acid fast staining Hanging drop preparation Phenol coefficient test. Virella G. Gaultheria. Tissue Culture & Mushroom Cultivation. Orient Longman. Experiments in Microbiology. 3. Fennel. Hugo and Russell. Microbiology. Black Well Scientific Publication. Eucalyptus. Balsam of tolu.. Dill. Ingraham.M.Y. 9. 7. Evaluation of disinfectants and antiseptics 7. Orange peel. Lemon grass. Delhi. Ananthanarayan R & Paniker CKJ. 6. Pelczar & Reid. 8. Sykes. Aneja K. Macmillan Press Limited. PHARM-243 PHAMACOGNOSY – II Unit-I : Resins : Study of drugs containing Resins and Resin Combination like Podophyllum. Microbial assay of antibiotics as per IP. Davis. Asafoetida. & Painter P.L. Citronella. Microbiology and Infectious Diseases. Textbook of Microbiology. Ginger. Valerian. Dulbetco. Coriander. 6. BOOKS RECOMMENDED : 1. & Klien D. 8. Tata Mc Graw Hill. [05] Unit-II : Volatile oils : General methods of obtaining volatile oils from plants. Plant Pathology. Turmeric. 42    . Musk. Pharmaceutical Microbiology. Shellac. Capsicum.A. General Microbiology.. Caraway. Test for sterility of pharmaceutical products as per IP. Balsam of peru. 10. 2.R. Cardamom.L. Lab Mannual of Microbiology.. Cassia. Study of volatile oils from Mentha. McGraw Hill. minimum inhibitory concentration. Oxford. Spearmint. Microbiology. Disinfection and Sterilization. Vishwa Prakashan. Cinnamon. Cannabis. Cumin. J. New Age Publishers. Harley J.

Role of aromatic plants in national economy. 3. wool. Gelatin and Natural colors. Glycosides. Flavonoids & Tannins. Utilization of aromatic plants & desired products will special reference to Sandalwood oil. [14] [03] [02] [03] [03] Unit-IV : Fibres : Study of fibres used in pharmacy such as cotton. Vetiver oil. Bentonite. Morphology of Mentha. Morphology and microscopy of Clove and to study its transverse section. flavonoids and Leucoanthocyanidine. classification and properties with Qualitative chemical tests of the followings – Alkaloids. Saponins. Morphology of Turmeric. polyester and asbestos. 3. Geranium oil & Eucalyptus oil. 7. Unit-V : Tannins : Study of tannins & tannin containing drugs like Gambier (Pale Catechu). Study of Cotton. PHARM-243P PHARMACOGNOSY – II PRACTICAL 1. 8. 5. Diatomite. 2. Cannabis. Morphology and microscopy of Cardamom and Fennel. Black Catechu. Pharmaceutical aids :. Cardenolides and bufadienolides. Baheda. Lemon grass oil.Sandalwood. and Kaolin. 2. Morphology and microscopy of Coriander and Cinnamon. cyanogenetic glycosides.Study of Pharmaceutical aids like Talc. Microscopic study of seven selected drugs and their powders mentioned under the category of volatile oils in theory with their chemical tests. Fullers earth. To study the morphology and chemical tests of Talc. SUGGESTED PRACTICALS 1. 43    . glasswool. Silk and Wool along with their chemical Tests. General chemical test for Alkaloids. Diatomite. Nutmeg and chenopodium. Morphology and microscopy of Dill and Caraway. Kaolin. Gall and Myrobalans (Harde. Identification of crude drugs mentioned in theory. Euncalyptus. Lemongrass. Steroids. nylon. 4. Arjuna & Ashoka). Mentha oil. Ginger. [10] Unit-III : Phytochemical Screening : An introduction to active constituents of drugs : Their isolation. silk. 6. Study of fibres and pharmaceutical aids. 4.

5.E. measuring the relative voltage of cell. 44    [08] [08] Unit-III : Demistrometry – Introduction. Tyler V.E.C. 11. 3. & Evans W.. London.” Pharmacognosy & Phytochemistry”. Test for identification of Tannins. Preparation of reagents for the chemical tests of Alkaloids and to perform the chemical tests on any Alkaloid containing drug. Tests for identification of flavonoids. Nernst equation. BOOKS RECOMMENDED : 1. 2. salt bridge. Trease G. PHARM-244 PHARMACEUTICAL ANALYSIS. Atal C. electrode potential. Karl. Morphology and microscopy of Bentonite. Harborne J B. Tests for identification of steroids.K. ((Monograph).II Unit-I : Theoretical considerations and application in drug analysis and quality control by the following analytical techniques (assays included in the Indian Pharmacopia 1996) (A) Non-aqueous titrations (B) Complexometric titration. 12.K. Pune. Philadelphia. Gelatin and natural colours (Soffron). “Cultivation & utilization of Medicinal plant. et al “Pharmacognosy” Lea & febiger. 7. RRL.9. Unit-II : (A) Miscellaneous methods of analysis : Diazotization titrations. 15. Kjeldahl method of Nitrogen estimation. reference and indicator electrodes. Jammu. 14.K. Alcohol estimation in galenicals Potentiometry (B)Radioassays. “Pharmacognosy” Balliere Tindall East Bourne U. 6. Wallis. . Chapman & Hall International Edition. Dielectric cell. Phytochemical method. 10. 13. Mohammed Ali.E. London. standard potential. et al “Pharmacognosy” Nirali Prakashan.Fischer titration. “Text Book of Pharmacognosy” J&A Churchill Ltd. To perform the chemical tests of Balsam (Tolu and Peru) and Asafoetida.. T. PROJECT WORK : Utilization of Aromatic plants. & Kapur BM. Kokate C. Test for indentification of Glycosides (Saponin and Anthraquinone). 4.

45    . Complexometric Titrations : Preparation and standardization of EDTA solution some exercise related to pharmacopoeial assays by Complexometric titrations. instrumentation and pharmaceutical applications.General principles. Exercise based on acid base titration in aqueous and non-aquous media. [08] [08] Unit-V : Principle. Kjeldahil. The Athlone Press of the University of London.J. Denny RC.B. Instrumentation and Applications PHARM-244P PHARMACEUTICAL ANALYSIS . instrumentation and applications. oxidation reduction titrations using potentiometric technique. A H and Stenlake. Delhi. 5. Chromatography. Miscellaneous Determinations : Exercise involving Diazotization.D. J. 6. 4.II PRACTICAL 1.Exercises involving conductometric titrations.Connors KA. Practical Phamaceutical Chemistry.layer chromatography. 3. Non-aqueous Titrations : Preparation and standardization of perchloric acid and sodium/potassium methoxide solutions. Beckett. 2. Pharmacopoeia of India. J. Conductometry : General Principles. published by The Controller of Publications. Barnes. Estimation of some pharmacopoeial products. Her Majesty’s Stationary Office.K. University Press. 2. Karlfisher. “Vogel’s Text Book of Quantitative chemical” Pearson Education Asia. BOOKS RECOMMENDED : 1. Cambridge. Wiley Intescience. TLC [08] Unit-IV: Polarography and Amperlometry. 3. A Textbook of Pharmaceutical Analysis. 4. instrumentation and applications. Mendham J. Vol. Potentiometry : General principles. column and thin. Paper column. 6.A. determination of acid base dissociation constants and plotting of titration curves using pH meter. Exercises based on paper. 5. Thomas M. G.” Instrumental Methods of drug Analysis”.Vidya Sagar. B. I and II. New York. British Pharmacopoeia.

parathyroid. AIDS. 6. Parkinson & Alzeimer’s diseases pathophysiology of cataract. Chatterjee C. cardiac cycle.A. 4. thyroid. Oxford University Press. Difore SH. 11. Human Anatomy. Niel.Diabetes mellitus. C. Pathophysiology of hypertension. physhosis. Churchill Livingstone. New Delhi. epilepsy.PHARM-245 ANATOMY PHYSIOLOGY AND PATHOPHYSIOLOGY –IV Unit-I – Respiratory System – Anatomy & function of respiratory structures. Harper & Rave Publishers. Menstruation.S. II & III. [06] . gout. Principles of Anatomy & Physiology. oogenesis. conducting system of heart. Elsevier. Ross & Wilson. Human Physiology. 9. glaucoma etc. Tuberculosis. Keele. CBS Publishers & Distributors. New Delhi. control of harmone secretion. Chaurasia B. [08] Unit-II – Cardiovascular System – Functional Anatomy of heart. Text book of Medical Physiology. Human Physiology. Delhi. WB Saunders Company. adrenal. pathophysiology pregnancy. CBS Publishers & Distributors. Calcutta.Male & Female reproductive system. pathophysiology of Asthma. Emphysema. Pneumonia. Parmar N. ECG (Electro cardiogram). of sexually transmitted diseases. regulation of respiration. Tortora GJ. Medical Allied Agency. Health Education & Community Pharmacy CBS Publishers. Hall JE.D. fatigue.. E and Joels N. Samson Wright’s Applied Physiology. Ischaemic heart disease. [08] Unit IV – Endocrine System – Anatomy & Physiology of pituitary. 8. 7. & Anagnodokos NP. 5. Shalya Subhash. 3. [10] Unit-III – Reproductive System. spasticity. hypersensitivity. Kumar V. pancreas.C. Angina. 10. Pharmacotherapy – A Pathophysiological Approach.. spermatogenesis. myasthenia gravis. BOOKS RECOMMENDED 1.g. CHF. “Atlas of Normal Histology” Lea & Febiger Philadelphia. WB Saunders. Dipiro JL. Anatomy & Physiology in Health & Illness.. 2. Robbins SL. Arteriosclerosis. Mechanism of respiration. Pathophsiology of anaemia. pathophysiology of hypo & hyper secretion of endocrine glands & their disorders e. cardiac arrhythmias. myocardial infarction. 46    [08] Unit-V. Guyton AC. allergic conditions. Regional & Applied Part I. tetany. Basic Pathology..Pathophysiology of Joints disorder – Arthritis. Bronchits.

Lipid metabolism : Oxidation of fatty acid & energetics.. components of protein synthesis. Biosynthesis of amino acids. 47    . inhibition of protein synthesis. biosynthesis of purine and pyrimidine. Unit-IV 7. Co-enzymes:Vitamins as co-enzymes and their significance. enzymes-kinetics and mechanism of action. its role in energy capture & control. Genetic Code and Protein synthesis. DNA replication. Biosynthesis of saturated and unsaturated fatty acids. Metabolism of galactose and galactosemia. mechanism of oxidative phosphorylation.. Metals as co-enzymes and their significance. significance. Unit-III 5. Biosynthesis of ketone bodies and their utilization. Gluconeogenesis and Glycogenolysis. 8. 6. 2. regulation of lipid metabolism. catabolism of amino acids and conversion of amino acids to specialized products. Biological Oxidation : The respiratory chain. Carbohydrate metabolism : Glycolysis. Enzymes :Nomenclature. essential fatty acids. Biosynthesis of RNA. Role of sugar nucleotides in biosynthesis and pentose phosphate pathway. Energetics of oxidative phosphorylation. The citric acid cycle. 4. Carcinogensis & DNA repair mechanism. Unit-II 3. [08] [08] [08] [08] Unit-V 9. mechanism of inhibition of enzymes and isoenzymes in chemical diagnosis. reactions and energetics of the cycle. formation of deoxyribonucleotides.SEMESTER -V PHARM-351 PHARMACEUTICAL CHEMISTRY – IV (BIOCHEMISTRY) Unit-I : 1.

12.. 8. New Delhi. Outline of Biochemistry. Determination of glucose by means of the enzyme glucose oxidase. An Introduction to Practical Biochemistry. 2.P. 4. Plummer. & Mazur A. Biochemistry. New York... 5. Separation of lipids by TLC. W. PHARM-352 PHARMACEUTICS – V 48    . “Harpers Review of Biochemistry” Lange Medical Publication. 6. New Delhi. Practical Manual to Biochemistry. 7. Lehninger Principles of Biochemistry.B.K.E. Quantitative estimation of amino acids. Titration curve for amino acids. Effects of temperature on the activity of alpha amylase. Nelson DL & Cox MM... Stryer L. Estimation of Urea in blood. ‘ Lehninger . 11. Singh S. Nelson. Mc Graw Hill. New Age International Publishers Delhi. phosphate and carbonate) and measurement of pH. BOOKS RECOMMENDED : 1. Conn E. 3. 4. 7. 3. Principles of Biochemistry”. 13. Qualitative analysis of inorganic as well as organic constituents of Urine. Estimation of cholesterol in Blood.. Saunders Co. 8. 9. Freeman & Company. Text book of Biochemistry.A Premier. 10. Narayanan P. 5. Bioinformatics.. 10. Enzymatic hydrolysis of glycogen by α & β amylase. Preparation of standard buffers (citrate.10. 9. Harrow B.. Macmillan Worth Publishers. Separation of amino acids by chromatography. (Prokaryote and Eukaryote) PHARM. & Stumph P. Laboratory Manual in Biochemistry.David. Philadephia. David J. 6. WH.351P PHARMACEUTICAL CHEMISTRY-IV (BIOCHEMISTRY) PRACTICAL [08] 1. Estimation of Glucose in blood & urine. Estimation of ketone bodies in blood. Jayaraman J. Regulation of gene expression. Wiley Eastern Limited. CBS Publisher. L. 2. San Francisco. John Willery & sons.

Shaving and after shaving products. stability and bioavailability. mechanisms of drug penetration. cleansing cream. preservatives. [08] Unit-IV : Suppositories : Ideal requirements. stabilizers. semisolid bases and their selection. types of additives used in formulations. colors. dielectric constant. general formulation. Hair structure. Manufacturing packaging & evaluation of clear liquids. Solubility. solubilizers. flavours and others. suspensions and emulsions. antiperspirants. suspending agents. bases. General formulation of semisolids.face powder. manufacturing procedure. factors fluencing penetration. Lipstick. manufacturing and packaging methods. particle size. Conditioner. Shampoos. Pharmaceutical Aerosols: Definition. vehicles. dissolution and organoleptic properties and their effect on formulation. types.(PHARMACEUTICAL TECHNOLOGY -I) Unit-I : Preformulation studies : Study of physical properties of drug like physical form. evaluation and packaging. protective cream. density. [08] [08] PHARM-352P PHARMACEUTICS-V 49    . all purpose cream. deodorant. Nail lacquer. shape.vanishing cream. packaging and evaluation. Propellants. [08] Unit-II : Liquid Dosage Forms : Introduction. emulsifying agents. formulation of cold cream. [08] Unit-III : Semisolid Dosage Forms : Definitions. pharmaceutical applications. Unit-V : Cosmetology and cosmetic Preparations : Structure of skin. Dentifrice & Mouthwash. clear gels & manufacturing procedure. wetting.

(PHARMACEUTICAL TECHNOLOGY-I)

PRACTICAL 1. Preparation of cold cream, vanishing cream, cleansing lotion and creams. Moisturising creams, Skin tonics, Hair creams, Hair Conditioners, Shampoos, Shaving creams and sticks. Tooth powder, Tooth pastes, After shave lotion and other cosmetic preparations. 2. Preparation, evaluation and packing of liquid orals like solutions, suspensions and emulsions, ointments, suppositories, eye drops, eye ointments etc. SUGGESTED PRACTICALS 1. Preparation, evaluation, and packing of (10 preparations =5 labs) I- Liquid Orals a) Solutions : Strong Sodium salicylate oral solution BP Chloral hydrate oral solution BP b) Suspensions : Magnesium sulphate oral suspension BP Milk of magnesia IP Aluminium hydroxide gel IP c) Emulsions : Liquid paraffin oral emulsion BP II – Semi-Solids d) Ointments Salicylic acid ointment BP Whitfield ointment BP Compound benzoic acid ointment III - Suppositories e) Suppositories : Glycerin suppositories BP Lactic acid suppositories BP 3. Preparation of cosmetic preparations (30 preparation = 10 labs) 1) Cold cream 2) Vanishing cream 3) Cleansing cream 4) All purpose cream 5) Protective cream 6) Foundation lotion 7) Sunscreen lotion 16) Cream shampoo 17) Clear liquid shampoo 18) Shaving cream 19) Brushless shaving cream 20) After shave lotion 21) Hair fixer gel 22) Tooth powder
50   

8) Face powder 9) Body powder 10) Hand cream 11) Face pack 12) Deodorant 13) Antiperspirant 14) Shampoo- powder 15) Oily shampoo

23) Tooth paste 24) Mouth wash 25) Hair conditioner 26) Anti dandruff shampoo 27) Depilatory cream 28) Bleach cream 29) Hair setting lotion 30) Tooth gel

BOOKS RECOMMENDED 1. Remington’s Pharmaceutical Sciences, Vol. I & Vol. – II, Mack Publishing Co., U.S.A. 2. J.W. Cooper, & G. Gunn, Tutorial Pharmacy, Petman Books Ltd., London. 3. Lachman L., Lieberman H.A, Kanig J.L, Theory and Practice of Industrial Pharmacy, Lea & Febiger, Philadelphia, U.S.A. 4. H.C. Ansel, Introduction to Pharmaceutical Dosage Forms, Lea & Febiger, Philadelphia, U.S.A. 5 R.L. Juliano, Drug Delivery Systems, Oxford University Press, Oxford. 6. Harrys Cosmetology 7. Balsam and Sagarin, Cosmetics: Science and Technology. 8. Thomssen E.G. Modern Cosmetics, Universal Publishing Corporation. 9. Mittal B.M. & Saha R.N.-a handbook of cosmetics, Vallabh Prakashan. 10. Harry G.Brittain,” Polymorphin in Pharmaceuticals Solids”.

PHARM-353 PHARMACOLOGY – I Unit-I : General Pharmacology – Introduction to pharmacology, routes of drug administration, combined effect of drugs,factors modifying drug action. Bioassay of drugs & Biological standardization. Discovery & development of new drugs. [07]

Unit-II : Basic Concepts of Pharmacokinetics- Absorption, Distribution, Metabolism, Excretion Pharmacodynamics ,Principles of drug action ,Mechanism of drug action , Receptors, Dose
51   

Response curve,Therapeutics index -LD 50 & ED50,. Adverse drug reactions & treatment of poisoning. drug interactions, Unit-III : Pharmacology of ANS Drug acting on autonomic nervous system I-Cholinergic systemParasympathomimetic (Cholinergic ) drugs. Parasympatholytic (anti Cholinergic) drugs. Drug acting on autonomic ganglia (Stimulants and blocking agents) II-Adrenergic system Sympathomimetic (Adrenergic) drugs Sympatholytic (Anti-adrenergic) drugs [08] [07]

Unit-IV : Pharmacology of CNS General Anaesthetics, Alcohols & disulfiram, Sedative hypnotics, Psychopharmacological agents-anti anxiety agents ,antipsychotics, antidepressants. Antiepileptic drugs, Antiparkinsonism drugs, Analgesics & antagonists. [12]

Unit-V : Drugs acting on PNS Local anesthetics Skeletal muscle Relaxants Peripherally and Centrally acting muscle Relaxants [06]

PHARM-353P PHARMACOLOGY- I PRACTICAL 1. Use of computer simulated CDs or Video cassetes for pharmacology practical where possible. 2. Preparation of different solutions for experiments. Drug dilutions, use of molar and w/v solutions in experimental pharmacology. Common laboratory animals and anesthetics used in animal studies. Commonly used instruments in experimental pharmacology. Some common and standard techniques. 3. Study of different routes of administration of drugs in mice/rats. To study the effect of hepatic microsomal enzyme inhibitors and induction on the pentobarbitone sleeping time in mice, using software alternative to use of animals.
52   

K. Goodman & Gilman. Ltd.K. New Delhi. Molinos. 9. Fundamentals of Experimental Pharmacology.G. MN.K: Text Book of Pharmacology. Salbutamol. 6.. Prentice Hall. Anticholinergic & Anticholinesterases-Neostigmine. BOOKS RECOMMENDED : 1. Scientific Book Agency. P. International.K.S. geometric and bioisosterism) of drug molecules and biological action. Essentials of Medical Pharmacology.[08] [08] Unit-III:Drugs acting on the Central Nervous Systerm : General Anaesthetics-Thiopental. Delhi.B. concept of prodrug. 2. Dale MM. Pilocarpine. ISBN 1-874758-02-6 PHARM-354 PHARMACEUTICAL CHEMISTRY -V (MEDICINAL CHEMISTRY –I) Unit-I : Basic Principles of Medicinal Chemistry: Physicochemical aspects (Optical. Limbird. Essentials of Pharmacology. Hardman.G. Singh. B. Sheffield Biocsience Programs. K.G. Barar F. Calcutta. Satoskar & Bhandarkar. Adrenergic Drugs-Ephedrine. Adrenaline. Atropine. Tripathi. Riter JM. Pharmacology & Pharmacotheropeutics. Basic & Clinic Pharmacology. 53    . Amphetamine. Vallabh Prakashan. Rang MP. 10.. CBS Publishers... Gil. Pharmacology Churchill Livingstone. Hand Book of Experimental Pharmacology.. Ghosh. Katzung.D. Delhi. Methohexital. [08] Mode of action. Pergamon press. New Delhi.W. uses. Bombay. Saundar. Interpoint. Kulkarni S. Methacholine.. L. Popular Prakashan Pvt. Jay Pee Publishers. U. R. structure activity relationship of the following classes of drugs (Synthetic procedures of individually mentioned drugs only) Unit-II : Drugs acting at Synaptic and neuro-effector junction sites: Cholinergic.E. 11. 5. 8. Editors: J. 4. Ketamine. Physostigmine. 7. New Delhi. Academia Publishers. Experiments in Pharmacy & Pharmacology. Drug-receptor interaction including transduction mechanism. 3. Ruddon and A. The Pharmacological basis of Therapeutics. Grover J.

Local Anaesthetics-Lignocaine, Benzocaine. Sedatives and Hypnotics-Phenobarbitone, Alprazolam. Opioid Analgesics-Pethidine, Methadone, Pentazocine. Unit-IV: Antitussives-Cramiphen, Dextromethorphen. Anticonvulsants-Phenytoin, Carbamazepine, Ethosuximide, Valproic Acid. Antiparkinsonism drugs-Carbidopa, Levodopa. CNS Stimulants-Caffeine, Nikethamide. Unit-V :Psychopharmcological Agents : Antianxiety drugs- Diazepam, chlordiaze Poxide. Antidepressants – Imipramine, Amitriptyline Fluoxetine. Antispasmodic and Antiulcer drugs-Dicyclomine, Ranitidine, Omeprazole. Skeletal muscle Relaxants– Gallamine Mephenesin, Antipsychotic- Chlorpromazine, Haloperidol. [08] [08]

PHARM -354P PHARMACEUTICAL CHEMISTRY-V (MEDICINAL CHEMISTRY-I) PRACTICAL 1. Synthesis of selected drugs from the course content involving two or more steps. 2. Establishing the pharmacopoeial standards of the drugs synthesized. SUGGESTED PRACTICALS 1. Synthesis of Methyl salicylate. 2. To establish pharmacopoeial standards of Methyl salicylate. 3. Synthesis of Paracetamol. 4. To establish pharmacopoeial standards of Paracetamol. 5. To synthesize Benzocaine. 6. To establish pharmacopoeial standards of Benzocaine. 7. Synthesis of Phenytoin. 8. To establish pharmacopoeial standards of Phenytoin.
54   

9. Synthesis of Barbituric acid desivatives. 10.To establish pharmacopoeial standards.

BOOKS RECOMMENDED : 1. Mann P G & Saunders B C, Practical Organic Chemistry, ELBS/Longman, London. 2. Furniss B A, Hannaford A J, Smith P W G and Tatehell A R, Vogel’s Textbook of Practical Organic Chemistry, The ELBS/ Longman, London. 3. Pharmacopoeia of India, Minsitry of Health, Govt. of India. 4. Wolff ME. Ed. Burger’s Medicinal Chemistry, John Wiley & Sons, New York. 5. Degado J.N. and Remers W A R, 10th eds., Wilson and Giswold’s Text book of Organic Medicinal and Pharmaceutical Chemistry, Lippincott, William & Wilkins. 6. Foye W C. Principles of Medicinal Chemistry, Lea & Febiger, Philadelphia. 7. Singh Harkrishan and Kapoor, V.K., Organic Pharmaceutical Chemistry, Vallabh Prakashan, Delhi. 8. Nogrady T, Medicinal Chemistry – A Biochemical Approach, Oxford University Press, New York, Oxford. 9. Finar I L. Organic Chemistry, Vol I & II, ELBS/ Longman, London. 10. Lednicer, D. The Organic Chemistry of Drug Synthesis Vol. I-V, John Wiley & Sons Inc. New York.

PHARM-355 PHARMACEUTICS – VI (PHYSICAL PHARMACY) Unit-I :(A) Matter, properties of Matter : States of matter, change in the state of matter, latent heat and vapor pressure, sublimation critical point, Eutectic mixtures, gases, relative humidity, liquid complexes, liquid crystals, glassy state, solids-crystalline, amorphous and polymorphism. [02] (B) Kinetics and Drug Stability : General considerations & concepts, Degradative pathways, half life determination, Influence of temperature, light, solvent, catalytic species and other factors, Accelerated stability study, expiration dating. ICH guidelines for stability. [05]
55   

(C) Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting is tonicity. [02] Unit-II: Micromeritics and Powder rheology: Particle size and distribution, average particle size, number and weight distribution, particle number, methods for determining particle volume, optical microscopy, sieving, sedimentation, measurement, particle shape, specific surface, methods for determining surface area, permeability, adsorption, derived properties of powders, porosity, packing arrangement, densities, bulkiness & flow properties. tension, surface free energy, measurement of surface and interfacial tension, spreading coefficient, adsorption at liquid interfaces, complex films,electrical properties of interface. Surface active agents, HLB classification, [08] solubilization, detergency, adsorption at solid interfaces, solid- gas and solid-liquid interfaces, Unit-IV : Viscosity and rheology : Newtonian systems, Law of flow, kinematic viscosity, effect of temperature, non-Newtonian systems, pseudoplastic, dilatant, plastic, thixotrophy, thixotropy in formulation, determination of viscosity, capillary, falling ball, rotational viscometers. Complexation : Classification of complexes, methods of preparation and analysis,applications. [08] Unit-V : Dispersion Systems : Colloidal Dispersions : Definition, types, properties of colloids, protective colloids, application of colloids in pharmacy; Suspensions and Emulsions; Interfacial properties of suspended particles, settling in suspensions, theory of sedimentation, effect of Brownian movement, sedimentation of flocculated particles, sedimentation parameters, wetting of particles, controlled flocculation, flocculation in structured vehicles, rheological considerations;Emulsions-types, theories, physical stability. [08] [07] Unit-III : Surface and Interfacial Phenomenon : Liquid interface, surface and interfacial

PHARM-355P PHARMACEUTICS – VI (PHYSICAL PHARMACY)
56   

compressibility. Lea & Febiger. Philadelphia.V. 13. porosity. Determination of half-life. Studies of different types of colloids and their properties.Physical Pharmacy. & Chun A. Accelerated stability testing. 3. 57    .PRACTICAL 1. Bustamante P.” Essentials of Physical Pharmacy”. BOOKS RECOMMENDED : 1. London. 11. Physical Pharmaceutics. Preparation of pharmaceutical buffers and determination of buffer capacity. 12. Studies of different types of complexes and determination of their stability constants. 2. 5. 9. Oxford University Press. Martin A. Experiments involving tonicity adjustments. Determination of surface/ interfacial tension. Particle size distribution and surface area using various methods of particle size analysis. Study of rheological properties of various types of systems using different Viscometers. 2. 6.H. 10. angle of repose etc. Preparation of various types of suspensions and determination of their sedimentation parameters. Determination of derived properties of powders like density.Derle . 3 D. 7. Preparation and stability studies of emulsions. 4. shelf-life determination and expiration dating of pharmaceuticals. Determination of particle size.C. rate constant and order of reaction. Shotten E & Ridgaway K. 8. HLB value and critical micellar concentration of surfactants. To study the influence of various factors on the rate of reaction.

II Cordiac glycosides & drug used for CHF-Digitoxin Antiarrhythmic drugs-Propranolol. worfarin Antihyperlipedmics.II) Unit-I-Drug Design Basic concept of drug design. Anticoagulants. Carmustine Antimetabolites. Spironolactone. Antibacterials – Sulphamethoxazole.Paracetamol. Chlorthiazide. Procainamide Antianginal drugs. Unit-IV : Analgesics and Antipyretics – Aspirin. Sulphacetamide. Sulphadiazine.Methotaxate 6.Chlorambucid. Diclofenac. Nifedipine. Introduction to Analogues based drug design.Isosorbide mononitrate Antihypertensive drugs-Captopril. Fluorouracil . Introduction to QSAR & Computer aided drug design. [08] 58    .Heparin. Furosemide.SEMESTER –VI PHARM –361 PHARMACEUTICAL CHEMISTRY-VI (MEDICINAL CHEMISTRY . methyldopa. [08] Unit-V: Diuretics – Acetazolamide. Ibuprofen. Nalidixic acid.Lovastatin. Mefeanamic Acid. Structure based drug design. mercaptopurine 5. Clofibrate [08] Unit-III Anti cancer drugs Alxylating Agents. [08] Unit.

London. Ed. Philadelphia. 7. 59    . Hannaford A J. Ministry of Health. Lippincott Co.PHARM-361P PHARMACEUTICAL CHEMISTRY -VI (MEDICINAL CHEMISTRY-II) PRACTICAL 1. 4. Philadelphia. Foye W C. ELBS/ Longman.II) Unit-I : 1. Medicinal Chemistry – A Biochemical Approach. 6. Organic Chemistry. Wilson And Gisworld’s Text book of Organic Medicinal and Pharmaceutical Chemistry.. Delagado J N and Remers W A R. 3. Pharmacopoeia of India. Burger’s Medicinal Chemistry.Thomas J. Pandi Veerapandian. Vol I & II. London. Finar I L. New York. Practical Organic Chemistry.. Capsules: Advantages and disadvantages of capsule dosage form. London. J. New York. quality control. soft gelatin capsule shell and capsule content.” Computer –aided Drug Design methods applications’. Smith P W G and Tathell A R. Oxford. methods of capsule filling. Furniss B S. Establishing the pharmacopoeial standards of the drugs synthesized.. size of capsules. stability testing and storage of capsule dosage forms.” Structure-Based Drug Design”. Delhi. 2. Govt.. 10. Principles of Medicinal Chemistry. 5. BOOKS RECOMMENDED : 1. V. Eds. PHARM-362 PHARMACEUTICS-VII (PHARMACEUTICAL TECHNOLOGY . 9. 3. John Wiley & Sons. 11. 8. Synthesis of selected drugs from the course content involving two or more steps. Mann P G & Saunders B C.K. Singh Harkishan and Kapoor. Wolff ME. Oxford University Press. Spectral analysis of the drugs synthesized. Vogel’s Textbook of Practical Organic Chemistry. T. Organic Pharmaceutical Chemistry.Perun. Vallabh Prakashan. material for production of hard gelatin capsule. ELBS/ Longman. of India. Lea & Febiger. Nogrady. The ELBS/ Longman. importane of base adsorption and minim/gm factors in soft capsule. 2.

vial. infusion fluids. ligatures and catguts.legal and other official requirements for containers. Unit-V : Surgical Products : Definition. official dressings. complex. surgical cotton. equipment for large scale manufacture and evaluation of parenteral products. stability aspects of packaging equipments. formulation. Stability kinetics and quality assurance. preparation of solution and suspensions. emulsion. lyophilization & preparation of sterile powders. water for injection. specifications and methods of evaluation. (B) Coating of Tablets : Types of coating. [8] Unit-II : Tablets : (A) Formulation of different types of tablets. pyrogenicity. washing of containers and closures. importance of microencapsulation in pharmacy. evaluation. package testing. containers and closures and their selection. Formulation details. Nasal and Ear products. Micro-encapsulation : Types of microcapsule. formulation of coating solution. Packaging of Pharmaceutical Products : Packaging component types. bandages. air suspension technique. evaluation of tablets. coating pan and other techniques. absorbable and non absorbable sutures. . film forming materials. routes of administration. filling and sealing of ampoules. factors influencing choice of containers. primary wound dressing. nonaqueous vehicles.2. In-vitro methods of 60    . spray congealing. different types of tablet compression machinery and the equipments employed. adhesive type. evaluation of micro capsules. protective cellulosic hemostasis. microencapsulation by phase co-acervation separation. evaluation of coated tablet. equipments for coating process. spray drying. granulation technology on large-scale by various techniques. absorbents. (B) Formulation and evaluation of Opthalmic. physics of tablets making. polymerisation. Prefilling treatment. [08] [07] [08] [09] Unit-III : (A) Approaches to Sustained and controlled release dosage forms. multi orifice. Unit-IV : Parenteral Products : Preformulation factors. surgical gauzes etc.

S.A. Marcel Dekker-Inc. Introduction to Pharmaceutical Dosage Forms. U. Granules USP/NF coating of granules) III .S. SUGGESTED PRACTICALS I – Preparation. Evaluation. a) Capsules : Chloramphenicol capsules IP b) Microcapsules : Coacervation Phase separation (Temperature change) c) Tablets : Uncoated – Paracetamol tablets IP d) Tablets : Film coated – Ibuprofen tablets IPs e) Tablets : Enteric coated – Aspirin tablets f) Parenteral : Disodium EDTA injection IP (vials) g) Parenteral : Dextrose – NaCl IV infusion IP (Infusion boilers) h) Parentrals : Water for infection IP (Ampoule) i) Eye drops : Zinc sulphate IP j) Eye ointment : Sulphacetamide Sodium IP II . Vol-I. Experiments to illustrate preparation. Avis. Lea & Febiger. 61    . Mack Publishing Company. tablets. Evaluation of Materials used in pharmaceutical packaging. U. H. parenterals & microcapsules.C. 2.E.A. 2. Remington: The Science and Practice of Pharmacy Pharmaceutical Sciences Vol.PHARM-362P PHARMACEUTICS-VII (PHARMACEUTICAL TECHNOLOGY . 3. New York & Basel. Philadelphia. Packing of the following dosage forms.Formulation and evaluation of sustained release dosage forms – Aspirin Extended release (Matrix embedding method. Pharmaceutical Dosage Forms : Parenteral Medication.II) PRACTICAL 1.Evaluation of packages – containers & closures. stabilization & physical evaluation of pharmaceutical products like powders. capsules. Ansel. BOOKS RECOMMENDED 1. R. I & III.

Oxford University Press. Antihypertensive drugs. To study the parallel shift of DRC in presence of competitive antagonist on DRC of Ach using Chicken ileum. Drug Delivery Systems. Herbert A. Antihyperlipidemics. R. U.GMP for Pharmaceuticals”. 62    . Unit-II : Drugs Acting on Haemopoeitic System Haematinics. K & anticoagulants. 5. To study the CRC of histamine on guinea pig on ileum preparation & study the effect of Antihistaminics using software. Thromboxane. Liebermann & Leon Lachman. 2. Respiratory Stimulants. Fibrinolytics & antiplatelet drugs. 4. Angiotensin and Bradykinin Unit-V : Drugs acting on GIT Antacids and Antiulcer drugs. To study effect of physostigmine on DRC of each on Chicken ileum. PHARM-363 PHARMACOLOGY-II Unit-I : Pharmacology of CVS: Cardiac glycosides. 5HT and their antagonists.Potdar. Theory & Practice of Industrial Pharmacy. Lea & Febiger. Juliano. PHARM-363P PHARMACOLOGY-II PRACTICAL 1.’ C. Anti-tussives & Expectorants. Plasma Volume expanders. Prostaglandins. Antiarrhythmics.S. Laxatives and antidiarrhoeal Agents. Unit-III : NSAIDS & Anti-gout Drugs. Emetics and antiemetics [07] [08] [08] [08] [09] Unit-IV : Autocoids: Histamine.Diuretics Leukotrienes. To record the dose response curve (DRC) of Acetylcholine using ileum of Chicken ilium. Vit. 3. Antianginal drugs. Drugs Acting on Respiratory System Anti-asthmatic drugs.A. Philadelphia. Manohar A.C.4. 6. Oxford.

CBS Publishers. Clinical Pharmacology. collection adulterants. Scientific Book Agency. 9.1-874758-02-6 PHARM--364 PHARMACOGNOSY – III Unit-I : (A) Study of the biological sources. ISBN. Editors:-JG Hardman. Kulkarni S. Rang MP. Ammi majus. Squill.BOOKS RECOMMENDED : 1. Pergamon Press.K. Tripathi. Pharmacology Churchill Livingstone. K. 4. 5. [04] [03] [03] Unit-II : Others : Psoralea. Modern Pharmacology. New Delhi. Ghosh. 63    . chemical constituents. Prentice Hall. 12.. New Delhi. Diosgenin. Coleus species. 8. Essentials of Medical Pharmacology. Vallabh Prakashan. 7. MN. Commercial varieties cultivation. Hand Book of Experimental Pharmacology. C.. Senna. Saffron. Katzung. 11.. Craig.D. Goodman & Gilman. Delhi. New Delhi. 1994..R. Biological sources. Interprint.K. Experiments in Pharmacy & Pharmacology. 3. Barar FSK : Text Book of Pharmacology. R. Chirata. Ltd. Laurence. diagnostic macroscopic and microscopic features n. Saponins : Liquorice. Sheffield Bioscience Programms. uses. The Pharmacological basis of Therapeutics. Glycosides : 1.III : Studies on traditional drugs : Common Vernacular name. Gentian.. DR & Bannet PN. 6. substitutes and specific chemical tests of following groups of drugs containing. Date MM. Fundamentals of Experimental Pharmacology. Bombay. Le Limbird. International. 2. Calcutta. 10. Riter JM.R. Pharmacology & Pharmacotherapeutics. Churchill Livingstone. Dioscorea. Rhubarb & Cascara. Jay Pee Publishers. Satoskar & Bhandarkar. and Stitzel. Basic & Clinical Pharmacology. 2. Little Brown and Co. Unit.. Ammi visnaga. Ginseng.K. Cardioactive sterols : Digitalis. Quassia and Andrographis paniculata. Solasodine & Podophyllotoxins [03] [03] (B) Production and Utilization of phytoconstituents such as calcium sennsoides. B. Grover J.G. Anthraquinone Cathartics : Aloe. Popular Prakashan Pvt. U.PB Molinoss. RW Ruddon & AG Gil. Stropanthus & Thevetia 3.

Siddha and Homeopathic systems of medicines. [07] Unit-IV : Punarnava. Morphology of Punarnava. Asavas. Kantkari. 2. Shilajit. Identification of crude drugs listed in theory 2. Morphology of Amla. 5. categories and common uses and toxicological activity of marketed formulations of following indigenous drugs : Amla. Methi. b) Identification Tests for Guggul lipids. Tailas. Apamarg. Morphology of Psoralia. 64    11 . Vach. To study the following standards) Loss on drying. Standardization of some traditional drug formulations. 3. Apamarg. Malkanguni and Neem. 7. Bhilwa. Chitrak. Tulsi. Morphology and microscopy (powder) of Liquorice along with its chemical tests. Gokhru. Gokhru. Palash. chemical nature of chief constituents. Gymnema. 3. Unani . SUGGESTED PRACTICALS 1. Gutikas. Kantkari.Satavari. 9. Brahmi. Majith.morphology. Morphology of Aloe and chemical tests on Aloe-extracts. Study of powdered drugs. Shankhpushpi. Churnas. Lehsun. 8. Morphology and microscopy (powder) of Rhubarb 4. 6. Morphology of Brahmi. Ammimaius. Kalijiri. pharmacology. [07] PHARM-364 P PHARMACOGNOSY . Nagarmotha. a) Morphology of Nagarmotha and Neem. Lehyas and Bhasmas. Guggul. Rasna. Introduction to Herbal Pharmacopoeia with special reference to. Tylophora. Shatavari and Vach. Saffron and Chirata. Arishtas. Lehsun and Palash. Microscopic study of some important glycoside containing drugs as outlined above. Methi. [08] Unit-V : Brief Introduction and principles of Ayurvedic. and Shankhpushpi. b) Extractive values.III PRACTICAL 1.

vol. Nadkarni A. Mohammed Ali. G. Compendium of Indian Medicinal Plants I-IV. Kokate C. 12. Jammu.Shah Prakashan. Indian Ayurvedic Pharmacopoeia. et al : “Pharmacognosy” Lea & Febiger. Gokhale SB.C. Nirali Prakashan. New Delhi. Preparation of medicated oil.E. 3.” Pharmacognosy & Plant Cultivation” 17. I&II.. The wealth of India..C. Medicinal plants of India I&II. “Pharmacognosy” Bailliere Tindall east Baorne.. Popular Prakashan (P) Ltd. 7. Indian council of Medical Reasearch.S. BOOKS RECOMMENDED : 1. 11. Atal C.E.K. “Analytical Microscopy” J&A Churchill Ltd. Wallis. T. Gokhale AS. 11.. of India. PROJECT WORK A report on marketed preparations based on traditional drugs mentioned in theory. Evans. 9. 10.K. U.E. RRL. 2. “Text Book of Pharmacognosy” J&A Churchill Ltd. Tyler V. 15. Rastogi & Malhotra. Cultivation of Medicinal Plants. 4. Philadelphia. Indian Pharmacopoeia. Trease. 6. “Practical Pharmacognosy” Vallabh Prakashan.K.c) Ash values. New Delhi. Govt. 8. W. 5. 14. 10) in any liquid Ayurvedic formulation. ICMR & RRL. Indian Herbal Pharmacopoeia.” Pharmacognosy” B.K. Bombay. 13. & Evans. 10. W.E. London. Jammu. Raw Materials (All volumes) Council of Scientific & Industrial Research. in water and alcohol of any Ayurvedic formulation (solid) available in the market. New Delhi. To perform above studies (exp. Kokate CK. Indian Materia Medica 1-2. d) pH of 1% solution. “Cultivation & utilization of Medicinal plants.. & Kapur BM. Qadry J. Wallis T. 65    .S. London.

Written skills: Proposal writings formats. Extempore Unit-V 8. Leadership Skills. Team work ‘BSC’ – Boss.Productivity. Exit Interview BOOKS RECOMMEDNDED 1. office etiquettes. Meenakshi & Sharma Sangeeta. Time Management simulation exercise 3. Technical Communications. Report writings Business letters Applications Covering letters. during the interview. Raman. Model interview (Video-shooting & displaying optional) 9. Various questions that may be asked in an interview.PHARM-365 PROFESSIONAL COMMUNICATION-II Unit-I 1. Group Discussions (G. Curriculum Vitae Designing Unit-II 2. Corporate behaviour. after the interview & on the day of interview. corporate expectation. 7. Subordinates & Collegues Unit-III 5.D) Tips GD Unit-IV 6. Oxford University Press. 4. [10] [06] [08] [06] [10] 66    . Interview Tips:What student is supposed to do before the interview.Principles & Practice.

3. Unit-II Ecosystems A. scope & importance B. Sharma R. PHARM.366 : ENVIRONMENT & ECOLOGY Unit-I Environment studies A. Introduction.Use. Food resources. exploitation and associated problems of forests. Mineral resources. Noise. Water resources. Lesikar’s Basic Business Communication. Land resources.Natural Resources – renewable & non renewable C. utilization. & Krishna Mohan.C. 1974 Unit-V Environmental Protection Act -1986 Noise Pollution Hazardous Wastes Hazardous Chemical Hazardous Microorganism Biomedical Waste 67    . Business Correspondence & Report Writing. Desert and Aquatic. Lesikar RV.Forest Grassland. Tata Mc Graw Hill Co.Introduction causes and control measures. types features & functions of difference ecosystems. D. Unit IV Law related to Environmental Protection Air (Prevention and Control of pollution )Act 1987 Water prevention & Control of Pollution Act.Equitable use of resources for sustainable life style. Biodiversity & its conservation with special reference to India. Thermal. Energy resources. Nuclear.Air. Water.2. Unit-III Environmental pollution.Definition. B. role of an individual in conservation. Marine. Soil.

M.Chemistry. chemical shift. Hyderabad. Instrumentation & Applications.Provisions applicable to drugs and cosmetic. spin spin splitting spectra of CH3-CH2-OH. 4. Hyderabad 3. deviation from Beer’s law. Compliances & Standards Vol.Electronic excitation. Instrumentation and applications Ultra violet and Visible. Instrumentation and applications. Principles of Environmental Studies.NMR.Inter pretation of IR . CH3-CHO. Manoharachary. single and double beam spectrophotometry. C6 H6. 2. Reddy. Instrumentation and application of GLC & HPLC. SEMESTER –VII PHAR M–471 PHARMACEUTICAL ANALYSIS -III Unit-I : Colorimetric Method. Reference 1. spin spin coupling.CH3-(CH2)4 CH3. Pharma Book Syndiacte. Pharma Book Syndicate. Acts. spectra of simple compounds. Fluorimetric Analysis.Theory of 1H. applications in pharmaceutical analysis.K.Theory.Anji . ‘ Text Book of Environmental Sciences & Techgnology”. [08] Unit-IIInfra-Red spectrophotometry-Theory. quantitative laws. Unit-III NMR Spectroscopy. Guidelines.Mass Spectroscopy –Theory. Shielding & Desheilding. mass spectra of some simple compounds. C. instrumentation and applications. R. P. Relevant Acts & Rules published by Govt. FTIR. Spectrophotometry. Handbook of Environmental Laws. Unit-IV Flame photometry-Theory . CH3 C6 H5. instrumentation. of India with latest amendments. [06] 68    [10] [08] .Trivedy. Atomic absorption spectroscopy. I &II. instrumentations. instrumentation and applications Unit-V Basic Principles. Jyaranama Reddy.

B. Pharmacopoeia of India. I and II. 4. Parikh V. Willard H. 2.W. 8. 1970. John Wiley & Sons. New York. Govt of India.PHARM-471P PHARMACEUTICAL ANALYSIS -III PRACTICAL 1. I & II Marcel. Principles of Instrumental Analysis. 6. Silver stein RM & Webster FX. 2. New York. 7. and Merrit L. Dekker. Interpretation of a few spectra. A text book of Pharmaceutical Chemistry Vol. Instrumental methods of analysis Van Nostrand Renhold. Ministry of Health. Assay of at least 10 official formulation containing single and more active ingredients using instrumental techniques. Becket A. Jr and Dean J.G. The Athlone Press of the University of London. New York. 5. Skoog V. Undergraduate Instrumental Analysis. Absorption Spectroscopy of Organic Molecules Addison-Wesley Publishing Co.H. and Stenlake J. Marcel Dekker Inc.. Biopharmaceutics : 69    .H. Spectrometric Identification of Organic Compounds.R.. Holler-Neimen PHAR M– 472 PHARMACEUTICS -VIII (BIOPHARMACEUTICS & PHARMACOKINETICS) Unit-1 :Introduction to Biopharmaceutics and Pharmacokinetics and their role in formulation development and clinical setting.A. 3. London 1974. Practical Pharmaceutical Chemistry Vol. Obonson J. BOOKS RECOMMENDED 1.H. Chatten L.

Unit-III:(A) Volume of distribution and distribution coefficient. Unit-V :Bioavailability and Bioequivalence : (A) Measures of bioavailability. [08] [08] [08] [08] PHARM-472P PHARMACEUTICS-VIII (BIOPHARMACEUTICS & PHARMACOKINETICS) PRACTICAL 1. (B) Compartment model and Non-compartment model. Statistical treatment of pharmaceutical data. (B) Pharmacokinetic drug interactions and their significance in combination therapy. 3. physiological and pharmaceutical. Experiments designed for the estimation of various pharmacokinetic parameters with given data. Loo-Reigelman method. plasma protein binding. 4. 2. (C) Clinical Pharmacokinetics : Definition and scope Unit-IV: (A) Dosage adjustment in patients with and without renal and hepatic failure. active transport. Definition and Scope. Determination of pharmacokinetic parameters from plasma and urine data after drug administration by intravascular and oral route. Unit-II : Pharmacokinetics : (A) Significance of plasma drug concentration measurement. and area under the curve (AUC). 70    . Absorption studies – in vitro. In vitro evaluation of different dosage forms for drug release. C-max. (B) Review of regulatory requirements for conduction of bioequivalent studies.(A) Passage of drugs across biological barrier (passive diffusion. (C) Drug distribution in the body. (B) Compartment kinetics – One compartment and Preliminary information of multicompartment models. (C) Pharmacokinetics of drug absorption – zero order and first order absorption rate constant using Wagner – Nelson. (B) Factors influencing absorption – Physicochemical. facilitated diffusion and pinocytosis).

To study the effect of hardness of tablet on dissolution rate. 16. To study the effect of various diluents on dissolution rate of dosage form (Tablets. suspension etc. 17.). 2. In-vitro dissolution study of the given fast release (M. In-vitro dissolution study of the given sustained release dosage form. Use of semilog paper. 3. 5. In-vitro drug release study of the given capsule dosage form using various dissolution media.D. In-vitro drug release study of the given powder dosage form using various dissolution media. 13. 15. To study the in-vitro drug.injection using both methods (Rate of elimination & sigma minus method one compartment model).) dosage form.drug interaction. 4. 8. 19. Operation of colorimeter & U.V bolus injection (one compartment model). Dispersible etc. To calculate the various Pharmacokinetic parameters from the given blood data of I. To calculate various Pharmacokinetic parameters from the given zero order drug release data. To calculate various Pharmacokinetic parameters from the given first order drug release data. 6.). 7. To determine the % protein binding of the given drugs. 4. 11. In-vitro drug release study of the given film coated dosage form using various dissolution media. To calculate various Pharmacokinetic parameters from the given urinary excretion data of I. 14.SUGGESTED PRACTICALS 1.V spectrophotometer. 2. DEMONSTRATION EXPERIMENTS 1. Capsules. To study the passive diffusion of the given drug using egg or goat membrane. To determine the various Pharmacokinetic parameters from the given blood data of oral administration of dosge form. 12. 3. In-vitro drug release study of the given uncoated tablet dosage form using different dissolution media. 71    . Preparation of Buffers & membranes. To determine the effect of protein binding on drug bioavailability. To study the effect of formulation on drug release (powder. 18. 10. Dissolution Apparatus. To study the passive diffusion of the given drug using cellophane membrane. 9. Ointment etc.V bolus.

Heavy metal Anatagonists. 5.G. Estrogens. organophosphorous & atropine poisoning. N. and Tozer T. opioids. 7. [10] Unit-V : Principles of Toxicology Definition of poison. Antibiotics – Penicillins.Y. John. Lea and Febriger. Sulfonamides. Parathormone. Basel. Hamilton. Wagner J. Technomic Publishing A. Cephalosporins. Quinolones. Clinical Pharmacokinetics.E. Viral diseases. Notari. PHAR M– 473 PHARMACOLOGY –III Unit-I : Pharmacology of Endocrine System Hypothalamic & pituitary hormones. Wagner J. Chloramphenicol. Thyroid hormones & Thyroid Drugs. 4.Y. Drugs Intelligence Publishers. general principles of treatment of poisoning with particular reference to barbiturates.. oral hypoglycemic agents & glucagon. 6. Fundamentals of Clinical Pharmacokinetics. G. Macrolides. Curry. Fungal infections. Tuberculosis. [07] [07] [08] Unit-II : ACTH & Cortico steroids. Oral Contraceptives. Leprosy.BOOKS RECOMMENDED : 1. StephenH. Drugs acting on uterus. [08] Unit-IV : Chemotherapy of Parasitic infections.N. “ Drug Disposition & Pharmacokinetics”. Androgens & anabolic steroids. 8.” Pharmacokinetics for the Pharmaceutical Scientist’.G. Rowland M. N. Biopharmaceutics and Pharmacokinetics – An introduction Marcel Dekker Inc. 3. Robert . Cotrimoxazole. Unit-III : Chemotherapy General Principles of Chemotherapy. Insulin. Milo’ Biopharmaceutics & Clinical pharcokinatics”. Calcitonin & Vitamin D.G. Pharmacokinetics for the Pharmaceutical Scientist. Introduction to Immunondulators and Chemotherapy of Cancer.Wagner. Gibaldi. Switzerland. Progesterone & 72    .” Analytical Techniques for Biopharmaceuticals Development”. R. 2. Rodriguezdiaz. Malaria. Tetracyclines.

. 5. 9.ISBN. Vallabh Prakashan. Chapman and Hall. To calculate the pA2 value of Atropine & chlorpheniramine. Kulkarni S. Interprint. 13. 8. Riter JM. Hardman. Prentice Hall. DR & Bennet PN. Surender. Ltd. Clinical Pharmacology.K.G.Sheffield Bioscience Programs.. Bombay. 10. B.G. Goodman & Gilman. New Delhi. Editors :. CBS Publishers. RW Ruddon & AG Gil. Calcutta. Churchill Livingstone. three point assay & four point assay.Bioassay of histamine and acetylcholine using matching and interpolation method on rat guinea pig . 2. Katzung.S. 14. U.. Satoskar & Bhandarkar : Pharmacology & Pharmacotheropeutics. 3. New Delhi. PHARM –474 PHARMACEUTICAL CHEMISTRY –VI (MEDICINAL CHEMISTRY . Popular Prakashan Pvt.PHAR-473P PHARMACOLOGY. Fundamentals of Experimental Pharmacology. Le Limbird. Pharmacology Churchill Livingstone. 3.K. Ghosh M. 11. uses . Jay Pee Publishers. Tripathi. bracketing assay. Laurene.. L..J. Pergamon Press. PB Molinoss. Rang MP. Scientific Book Agency. 4. New Delhi. Principles of Pharmacology. 1-874758-02-6. Basic & Clinical Pharmacology.III PRACTICAL 1. histamine & oxytocin on suitable isolated preparations using matching assay. Bioassay of Ach. structure-activity relationship of the following classes of drug (Synthetic procedures of individually mentioned drugs only). International. K.K : Text Book of Pharmacology. 7. Experiments in Pharmacy & Pharmacology. All experiments will be conducted using software wherever possible. Essentials of Medical Pharmacology. Unit-I : 73    . Barar F. Delhi. Pergamon Press.N. 6. Paul.K. Singh. 2. The Pharmacological basis of Therapeutics. Grover J.D. 12. Essentials of Pharmacology. Delhi. Academa Publishers. Dale MM.III) Mode of action. BOOKS RECOMMENDED : 1. Hand Book of Experimental Pharmacology.

Ministry of Health. Diloxanide Antiseptics & Disinfectants – Benzalkonium chloride Anthelmintics. Cephalosporins. Delhi. Pyrimethamine. Levothyroxine. Vallabh Prakashan. tetracyclines. Singh Harkrishan and Kapoor. 74    . Lea & Febiger.HIV agents-Zidovudine. Chloramphenicol. Semi-synthetic penicillins. Lamivudine. [08] Unit-II : Antibiotics-Penicillin. Dexamethasone. Burger’s Medicinal Chemistry. Philadelphia. Stanazolol. Primaquine. J. Principles of Medicinal Chemistry. Methimazole. Delagado J N and Remers W A R. Acyclovir. Tinidazole. New York. Antimycobacterial Agents:PAS.Glibenclamide. 2. Antiamoebics: Metronidazole. Antivirals –Amantadine. Carboprost. 5. Prostaglandins –Misoprostol.Saquinavir. streptomycin. Dapsone Antimalarials: Cholroquine. [08] [08] [08] BOOKS RECOMMENDED : 1. 4.. (C) Adrenocorticoids – Prednisolone. Ethambutol. Govt. Philadelphia. Unit-V :-Thyroid and Antithyroids – Carbimazole. V.1. Isoniazid. Eds. Steroids and related drugs : Introduction.. 3. Metformin..Insulin Chlorpropamide. Tolbutamide. Organic Pharmaceutical Chemistry.Griseoflain and Clotrimazole Unit-IV : – Anti. Wolff ME. Zalcitabine. Hypoglycaemics . Ed. Nomenclature. Propylthiouracil. Stereochemistry (A) Androgens and Anabolic steroids – Testosterone. Fluroquinolones. Foye W C. of India. Betamethasone.Mebendazole Antifungals :.K. Estradiol. Wilson And Gisworld’s Text book of Organic Medicinal and Pharmaceutical Chemistry. Classification. Lippincott Co. John Wiley & Sons. Pharmacopoeia of India. (B) Estrogens and Progestogens – Progesterone.

Ipecac & Opium.. (B) Tropane :Belladona. Digitalis. Unit-II : (E) Imidazole : Pilocarpus. (C) Quinoline & Isoquinoline : Cinchona. Hyoscyamus. uses. London. Diosgenin. Oxford University Press. 75    [08] [08] . Nogrady T.6. Comprehensive Medicinal Chemistry. cultivation. Rauwolfia. Aloe. Utilization & production of phytoconstituents such as – Tropane Alkaloids. processing. Catharanthus & Nux-vomica. Hanch C. (D) Indole : Ergot. Taxol. Papain. Quantitative Drug Design. collection. Vol. (G) Alkaloidal amine : Ephedra & Colchicum. 8. Medicinal Chemistry – A Biochemical Approch. (A) Pyridine-piperidine : Tobacco. (H) Glycoalkaloid : Solanum. & plant laxatives. Vol. Pergamon Press. PHARM-475 PHARMACOGNOSY-IV Unit-1 : 1. Datura. IV. commercial varieties. ELBS/ Longman. Ginseng. (I) Purines : Coffee & Tea (J) Quinazoline : Vasaka. 7. Isoquinoline & Quinoline Alkaloids. I & II. Coca & Withania. Unit-III (A) World wide trade in Medicinal plants & derived product. New York. diagnostic macroscopic& microscopic features & specific chemical tests of following alkaloid containing drugs.Oxford. Ipecac. chemical constituents. (F) Steroidal : Veratrum & Kurchi. Tropane alkaloids containing drugs. Areca & Lobelia. Cinchona. Liquorice. substitutes adulterants. Finar I L. Valerian. Organic Chemistry. Rauwolfia.Oxford. Systematic study of source.

Historical development of plant tissue culture. Plant Bitters & Sweeteners. To study the TLC profile of Withania root. To study the morphology and microscopy of Solanum and Vasaka. Chemical evaluation of powdered drugs & Enzymes. SUGGESTED PRACTICALS 1. Streptokinase. 4. Introduction of plant-tissue culture techniques on laboratory scale. Microscopic study of characters of any 8 selected drugs given in theory in entire and powder form. To study the morphology and microscopy of Catharanthus and Nux-vomica. classification & study of different chromatographic methods. [08] [08] Unit-V :Introduction.(B) Role of Medicinal & aromatic plants in National Economy. type of culture. 9. To study the morphology and microscopy of Ephedra and Kurchi. 7. 8. To study the morphology and microscopy of Datura and Withania. Nutritional requirement. 76    . Chemical test of Tea. Chromatographic studies of some herbal constituents. 2. and Kurchi. 3. To study the morphology and microscopy of Ipecac and Rauwolfia. a) Morphology of Areca. To study the TLC profile of Catharanthus leaf. Datura and Withania. Chemical test of Nux-vomica. Application PHARM-475P PHARMACOGNOSY -IV PRACTICAL 1. 11. growth & their maintenance. 3. Identification tests and uses of following enzymes – Diastase. Penicillinase. Unit-IV [08] Biological sources. of chromatographic techniques in evaluation of herbal drugs. Identificaiton of crude drugs listed above. Colchicum. 4. Hyalluronidase. Some experiments in plant tissue culture. Tobacco. Ephedra. 5. b) Transverse section of Catharanthus leaf and Kurchi bark. papain. 2. preparation. 6. 10. Application of plant tissue culture in pharmacognosy. 5.

E. Henry TA. “ Pharmacognosy” B. New York. U. ND. etal Pharmacognosy. 11. Thin Layer Chromatography. Text book of Pharmacognosy” J&A Churchill Ltd. 77    . 7. Mohammed Ali. Gokhale SB.. Dixit. Kokate. 5. The Pharmaceutical Press. Ganborg & Wetter.” Pharmacognosy & Phytochemistry”.E. 10. Indian Pharmacopoeia. “Pharmacognosy” Bailliere Tindall East Bourne. 12. Academic Press. Lea & Febiger Phjadelphia. London. G.S. E.Shah Prakashan. 4.BOOKS RECOMMENDED : 1. A laboratory handbook. Clarke ECG. 17.E. 2. W.K. McGraw Hill. Qadry J. Jammu.K. Pharmaceutical Biotechnology. 16. Isolation & Identification of drugs.” 9. Street H. Cultivation of Medicinal Plants. Atal & Kapur. & Evans. Delhi. Wallis T. Plant Tissue Culture Methods. 15. S.. CBS Publication.P. Berlin. C. Saskatchewan. C. Wallis T.K. Analytical Microscopy. RRL. 13.” Pharmacognosy & Plant Cultivation”. Kokate. Mohammed Ali. Tyler V.K. Trease. J&A Churchill Ltd. 3. 14. Nirali Prakashan. London. 6. London. National Research Council of Canada. Vallabh Prakashan. Cultivation & Utilization of Medicinal Plants. Springer Verlog.E. The Plant Alkaloids. Practical Pharmacognosy. London.E. Gokhale AS.S. Stahl. V. Vyas. Tissue Culture & Plant Science. 8.C.

development of hybridoma for monoclonal antibodies. Isolation of mutants and factors affecting mutation. Stanbury & A. 2. CBS Publishers and Distributors. factors affecting enzyme kinetics. Screening of soil for organisms producing antibiotics Antimicrobial spectrum and methods used for their standardization. Cellular. 4th Ed. standardization and storage of BCG. Pharmaceutical Biotechnology. BOOKS RECOMMENDED : 1. Unit-V : Enzyme immobilization : Techniques of immobilization of enzymes. transduction. [08] Unit-II : Genetic Recombination Transformation.F. Vyas and V. and humoral immunity. Delhi. protoplast fusion and gene cloning and their applications. streptokinase and streptodaranse. immunological tolerance.SEMESTER – VIII PHARM –481 PHARMACEUTICAL BIOTECHNOLOGY Unit-I : Immunology and Immunological preparations : Principles. conjugation.antigen-antibody reactions and their applications. biotranformation processes and its improvements with special reference to steroids. Design of Bio-transformation process. Insulin. its design and control of different parameters. study of drugs produced by biotechnology such as Activase. [08] Unit-III : Antibiotics : Historical development of antibiotics. study of enzymes such as hyaluronidase. amylases and proteases Immobilization of Bacteria and plant cells. Somatotropin. 3.P. penicillinase. Fermentor. Unit-IV : Microbial Transformation : Introduction. P. S. Prescott and Dunn’s Industrial Microbiology. Antigen and haptens. Ahhitar Principles of Fermentation Technology. Dixit. selection of organisms. CBS Publication. 78    [08] [08] [08] . immune system. New Delhi. 1987.K. types of reactions mediated by microorganisms.

terpenes. P. Citral. Standury & A. Recent developments of natural products used as anticancer agents.F. Diosgenin & Sarasapogenin ii) Lignans iii) Quassinoids iv) Flavonoids (Quercetin) Unit-III : Alkaloids – Atropine & related compounds. Panima Publishing Corporation. quinine. D. 7. Biotechnology-A Textbook of Industrial Microbiology. Johan.J. Isolation & Characterisation of – Terpenoids.Carotene. New Delhi. Whitaker & Hall S. β. and Vinca Alkaloids. steroids) Brief introduction to biogenesis of secondary metabolites of Pharmaceutical importance. Unit-V Herbal Cosmetics and their formulation. antidiabetics and immunomodulators. Kieslich Ed. ephedrine.Camphor. Crueger W.4. Photosensitizing agents and fungal toxins. 5.Digitoxin. Natural Allergens. 6. Delhi. Digoxin. Aditya Book Private Limited. Isolation & Chemistry of – i) Glycosides . [02] [03] [08] [08] [08] 79    . papaverine. Principles of Fermentation. Hecogenin. Unit-II Extraction. 2. reserpine. Chemical & Spectral approaches to simple molecules of natural origin. & Crueger A. morphine. K.” Biotechnology & Fermentation” PHAR M–482 NATURAL PRODUCTS Unit-I : 1. ergot. α -Tocopherol. Biogenetic Investigations and basic metabolic pathways. α-Pinene. (alkaloids. Biotechnology Vol. Menthol.Souza. Unit-IV: Extraction. 69 Verleg Chernie Switzerland 1984.

80    .S. 4. 4. 2. U. Isolation of Caraway oil from caraway.C. International Ed. London. Isolation of cumin oil from cumin. Medicinal Plant Alkaloids & Glycosides. 8. Trease G.” Pharmaconosy “B. Isolation of caffeine from Tea leaves. The Practical evaluation of phytopharmaceutical. Harborne. & Evan. “Pharmacognosy” Bailleire tindall East bourne.. Isolation of Clove oil from clove.L. I & II ELBS.S. Tyler V. Sim. 3. 9.E. 6. J. Stahl E. 2. To perform the column chromatography of herbal drug. Pharmacopoeia of India. Meerut. I.R. etal “Pharmacognosy” Lea & Febiger Philadelphia. Extraction of volatile oils & theirs chromatographic profiles.. 7. House. 10. New Delhi. W. 5. Qadry. “Chemistry of Organic Natural Product” Vol. “Practical Pharmacognosy” Vallabh Prakashan. “Thin layer chromatography” A Laboratory Hand Book. Springer Verlag. I & II Goel Pub. 11. To study the paper chromatographic profile of glycone portion separated from senna. 11.K. K. 6.B. O. separation. 10. To study the TLC profile of extracted oils. 7. Agarwal. 8.. Quantitative determination of Ascorbic acid present in Amla. BOOKS RECOMMENDED 1.E. Exercises on paper & thin layer chromatographic evaluations of herbal drug constituents. SUGGESTED PRACTICALS 1.K. Finar “Organic chemistry” Vol. London. (Fresh/ Dry). Brain. To Isolate the active constituent of any available drug with the help of preparative TLC. Wright. 3. purification of various groups of chemical Constituents of Pharmaceutical significance.D. Isolation of Hesperidin from Orange Peel. Phytochemical Methods Chapman & Hall. 5. Isolation of piperine from Black Pepper. Bristol. 2.P. Kokate C.. 3. Laboratory experiments on Isolation.PHARM-482P NATURAL PRODUCTS PRACTICAL 1. 9. J. Berlin. & Turner T.Shah Prakashan.

Innovation Creativity. demand curves labor welfare. keeping and pricing of stocks. Operative Management (Personnel. general principles of insurance and inland and foreign trade. Unit-III 3. Salesmanship : Principle of sales promotion. balance sheet. Bank reconciliation statement. 3rd Ed. promissory notes and bundles documentary bills. Entrepreneurship development. Biosynthetic pathway Higher plants. Pharmaceutical Marketing : Functions. [03] Accountancy : Principles of Accountancy. Production. 13. Delhi. Decision making. treatment of cheques bills of exchange.12. PHARM. Margin/ Morale) Principles of Management (Coordination. Communication. profits and loss account. evaluation . Concept of Management : Administrative Management (Planning. procedure of exporting and importing goods.483 PHARMACEUTICAL INDUSTRIAL MANAGEMENT Unit-I : 1. John Wiley & Sons. retail. Sharma PP. leadership. Marketing. Organising Staffing Directing and Controlling). training. merchandising. Recruitment. demand schedule. detailing. purchase. Academic Press. New Jersey. wholesale. compensation to the pharmacist. Ledger posting and book entries preparation of trial balance. transportation. Cosmetics formulation. Indian Pharmacopoeia. 15. Financial. Motivation. [04] [04] 81    . 14. buying. advertising. rectification of errors. Materials. Delegation of Authority / Responsibility. [12] Unit-II Economics : Principles of economics with special reference to the Laws of demand and supply. literature. ethics of sales. department store. New York. selling.. channels of distribution. Record Keeping). Abraham DJ. Time/space. Berger’s Medicinal Chemistry & Drug Discibery. Pridham JB & Swain T. multiple shop and mail order business. Vandana Publishers. [04] 4. Identification of key points to give maximum thrust for development and perfection. Manufacturing & Quality control. columns of a cash book. storage financed feedback information.

R. BOOKS RECOMMENDED : 1. Methodology of Activities Performance Evaluation Technique Process –Flow. Barthwal R.N.K. Tata Mc Graw Hill. Market Researth – Tata Mc Graw Hill 2.. inventory control and evaluation of materials management. [04] 7. Maintenance Management. 7. Pharmaceutical Selling. Shreenivasan K. Market share and future demand. Massie L. 11. Joseph Essentials of Management / PHI. / New Age International. Chadwick Leslie. Essentials of Management. 8. Daver Rustam S. Beri. Chary S. Vidya sagar Pharmaceutical Industrial Management. Production Management : A brief exposure of the different aspects of Production Management – Visible and Invisible inputs. (B) Market segmentation & Market targeting. Material Management / PHI. Datta A. Industrial Economics –.Vidya Sagar. 3. Materials Management : A brief exposure of basic principles of management major areas. Production and Operative Management / Tata Mc Graw Hill. Weihrich H. Estimating industry sales. 10. Salesmanship and Publicity –/ Vikas. G. purchase. Estimating current demand Geo-demo-graphic analysis. Koontz H. stores. 5. Process Know-how.” Pharmaceutical Industrial Management”. 6. Unit-V 6.Major concept in demand measurement.R. scope. The essence of management accounting / PHI. 4. Sterling Publishers. Pharma Book Syndicate 12. An Introduction to Industrial Management –/ Vikas.Unit-IV 5.. Market Research (A) Measuring & Forecasting Market Demand . [03] [06] 82    . 9. Mukopadhyay Sekhar.

sterilization equipments. procurement and stocking.. Purchase and Inventory control: Principles. Types of drug distribution systems Charging Policy. case on drug interaction & adverse reactions. Master formula record . personnel requirements.PHARM. Unit-V: Drug distribution systems in Hospitals : Out-patient dispensing. Dispensing of controlled drugs. purchase procedures. Medication error. procurement of information. Patient medication profile. Unit-II : Drug Store Management and Inventory Control: Organization of drug. Manufacturing records. Pharmacy and therapeutic committee.484 HOSPITAL PHARMACY Unit-I: Organization and Structure: Organization of a hospital and hospital pharmacy. Responsibilities of a hospital pharmacist.g. purchase order. Hospital Formulary: Contents. idiosyncratic cases etc. methods adopted. storage conditions. Unit-III : Central Sterile Supply Unit and their Management: Types of materials for sterilization. Records and Reports : Prescription filling drug profile. packing of materials prior to sterilization. demand and costing. 83    . Budget preparation and implementation. treatment schedules. Types of materials stocked. Manufacture of Sterile and Nonsterile Products: Policy making of manufacturable items. computerized services (e. Production control. Retrieval of information. MEDLINE). Dispensing of drugs to in-patients. Unit-IV: Drug information service: Sources of information on drugs. Supply of sterile materials. manufacturing practice. preparation and revision of hospital formulary. labeling. Dispensing of drugs to ambulatory patients.

microscopical. Merchant H. Production of radio pharmaceuticals. Shah Prakashan. Lea & Febiger. (E) Pharmaceutical Packaging (f) Novel drug delivery system (G) GMP. 2. PHARM –485 ELECTIVE Any one of the following: (A) Standardization of herbal drugs. BOOKS RECOMMENDED 1. Radiation hazards and their prevention. methods of isotonic tagging. permissible radiation dose level. preparations. preparation of radioisotopes in laboratory using radiation dosimetry. and Qadry J. Pharmacy and Drug interactions (D) Pharmaceutical marketing. organoleptic. radio-isotope generators. physical & chemical evaluation of crude drugs.Nuclear Pharmacy : Introduction to Radiopharmaceutics. Quality Assurance & Validation (A) STANDARDISATION OF HERBAL DRUGS Unit I – Commerce and quality control of natural medicinal plants products. Ahmedabad.S. B. Text Book of Hospital Pharmacy. (B) Drug design.radio-active half life. a) Anti-inflammatory b) Hypoglycaemic c) Antibacterial 84    [08] [08] [08] [08] Unit-III -Methods of extraction and modern techniques for the isolation. Hasan. Units of radioactivity. specifications for radio-active laboratory. (C) Clinical. Hospital Pharmacy.Standardisation of plant material as per WHO guidelines. Philadelphia.S. Unit-II . purification. separation Unit-IV -Analysis of official formulations derived from crude drugs including some ayurvedic Unit-V -General methods of screening of natural products for following biological activity: . estimation and characterisation of active plant constituents.S.

Indian herbal pharmacopocia. 2..Text book of Pharmacognosy 4. Harborne Phytochemical methods of chemical analysis . [08] Unit-II Drug metabolism-Phase I & Phase II Metabolic Reactions. & Srimal R. Physiochemical properties in relation to biological action. Prodrugs & Soft drug concepts [08] Unit-III Analogoues based drug design concept with suitable examples Structure Based drug design concept with examples. British herbal phamacopocia. E. Swendson Chromatography of alkaloids.. Lead Discovery.D. R. [08] 85    . Pharmacoepial standards for Ayurvedic formulations CCRAS.. 5. Interactions(Forces) involved in drug receptor complex. Trease. Sterochemical aspects in drug design. Bioisosterism. & Tracey MV. Delhi. The use of pharmacological techniques for evaluation of natural products.R. Wallis T. 10. Vapoorte. 13. 14. Elements of chromatography 8.E.A.C..N. Clerk’s isolation & identifications of drugs [08] 9. Brady Lynn. 7. Pharmacognosy ELBS. The practical evaluation of phytopharmaceuticals 11. Mottal. Evans W.d) Antifertility e) Psychopharmacological BOOK RECOMMENDED 1. Tyler Varro. G. and Turner T. Modern methods of plant analysis 12.E.R. Lala P. CDRI Lucknow.C..K. Brain K. Herbal drug industry (B) DRUG DESIGN Unit-I Introduction to Drug Design. Peach K. Dhavan B. 6. Robbers J.R. Pharmacognosy 3.E. Chaudhary.C.

Liver function. New York. Assessing causality. R. Wolff. Hematological. 3. John Willey and Sons. patient counseling.F.A. Reporting adverse drug reactions. Monitoring an detecting adverse drug reactions. S. Salkovisky. 86    .” Structure Based Drug Design”. Physical Chemical Properties of Drugs. Adverse drug reactionEpidemiology.Perun <’ Computer aided Drug Design methods Applications”.J. Quantitative models. Thomas J. 4. E. 2. Computer Aided Drug Design-Introduction & Softwares used in CADD [08] Unit-V QSAR Introduction. Pandi Veerapandian. New York (1975). parameters. 7.E. Academic Press. renal function. Classification. A. development and scope Unit-II PATIENT DATA ANALYSIS The patient’s case history. M. Doerge. New York. Burger A “A guide to chemical basis of Drug Design “John Wiley & Sons”. Wilson and Gisvold’s Text Book of Organic Medicinal and Pharmaceutical Chemistry. Parallel and Split & Mixed synthesis.J.Hansch method & Soft ware’s in QSAR. Marcel Dekker Inc. Olson. Risk factors.Unit-IV Combinatorial chemistry-Introduction.H. Philadelphia. Tests associated with cardiac disorders. Ariens: Drug Design.C. (C) CLINICAL PHARMACY AND DRUG INTERACTIONS Unit-I INTRODUCTION TO CLINICAL PHARMACY Definition. 6. Communication skills including patient medication history interview. 8. Valvani. its structure and use in evaluation of drug therapy. Edward C “Computer Assisted Drug Design (American Chemical Society). [08] BOOKS RECOMMEDED: 1. Burger’s Medical Chemistry. Sinkula and S. Lippincott Co. 5.

Basic skills in interpreting laboratory data. Biopharmaceutics and Applied Pharmacokinetics-Leon Shargel. Unit. Categories of Phase IV studies. 3.Estimation and determinants of bioavailability. Parthasarthi G.Calculation of loading and maintenance doses. 7.. 1997. and Hirashman J. REFERENCES 1. ELBS/Churchill Livingstone. clinical review. Herfindal E.The Society of Hospital Pharmacists of Australia. Nyfort-Hansen K. 4. Renal and non-renal clearance. Guidelines for good clinical research practice and ethical requirements.C. Ward round participation Drug utilization evaluation (DUE) and review (DRU). Davisson’s Pranciples and Practice of Medicine.Wagner.. Prentice Hall publication. 6.L. hepatic dysfunction. 8. Unit-IV RESEARCH DESIGN AND CONDUCT OF CLINICAL TRIALS Research support including planning and execution of clinical trials.Quality assurance of clinical Pharmacy services. American Society of Health System Pharmacists. TDM pharmacist interventions. Various phases of clinical trials. Practice Standrds and Definitions. A Text book of Clinical Pharmacy Practice –Essential Concepts and Skills. 87    . Williams and Wilkins Publication.. USA. Relevant review articles from recent medical and pharmaceutical literature.Dose adjustment in renal failure. Clinical Pharmacy and Therapeutics Williams and Wilkins 9. Inc.Scott LT. John g. 2. Nahata M.” Pharmacokinetics for the Pharmaceutical Scientist”.T. geriatric and paediatric patients. Orient Longman.Unit-III DAILY ACTIVITIES OF CLINICAL PHARMACISTS Drug therapy monitoring (Medication chart view. 5.V CLINICAL PHARMACOKINETICS Physiological determinants of drug clearance and volumes of distribution. Clinical Pharmacokinetics-Rowland and Tozer.

Pharmacopoeial tests and specifications. 4. (D) PHARMACEUTICAL MARKETING Unit-I Principles of marketing management. 2. New concepts in pharmaceutical packaging.” Biopharmaceutics& clinical pharmacokinatics’.Advertising. Identification of the marketing. Stability of package and packaging material. [08] 88    [08] [08] . Kotler. Pearson Education Asia. Philip “Marketing Management”. “ Drug Disposition & Pharmacokinetics”.10. 2. Market analysis. Curry. control of packaging materials. 6. Gibaldi. Ancillary materials used in packaging. Testing of containers & closures. Detailing.H. metals. Mickey C. Unit-III 5. Stephen. package design research. Unit-II 3. “Principles of pharmaceutical marketing”. [08] BOOKS RECOMMENDED 1. Defects in packages. Retailer. Blister and strip packaging. Smith. International marketing. Package systems. Market behaviour. Wholesaler. 11.Internal control and external control. Patient motivation. Hospital & Government agencies. CBS Publishers & Distributors. Unit-II Drug development and the marketing research interface. (E) PHARMACEUTICAL PACKAGING Unit-I 1. Selection of stockists and distributors. Introduction to pharmaceutical marketing. Milo. Unit-V Controls. 7. Marketing generic drugs. Packaging materials with special reference to polymers. Prescribing habits of physician. [08] [08] [08] [08] Unit-III Economic and competitive aspects of pharmaceutical industry. glass and plastics. Unit-IVDistribution channels in pharmaceutical marketing – Manufacuturer. Retail competition. Diversification and specialisation.

2. Pointing requirements.. Packaging of Parenterals. Microencapsulation: Methods. Transdermal drug delivery systems: Theory. Ross. ionotophoresis. 4. Quality-Control of Packaging Materials in Pharmaceutical Industry.D. General methods of design and evaluation of C.S. Unit-III 5. design and evaluation methods.D. 6. Kac Chensney. Unit-V 10. Brien. Sterilization of packaging materials. 9.O.D. Legal requirement. 5.S. Barail. Osmotic pumps. Packaging of Cosmetics and Toiletories. Packaging of Pharmaceuticals. (F) NOVEL DRUG DELIVERY SYSTEM Unit-I 1. 3. Theory of controlled release drug delivery systems. Physical.D.Unit-IV 8. label and leaflets preparation. 2. 4. kinetics of drug release from microcapsules technology and applications. Carriers for drug delivery systems. Implants and inserts: Types. Release and diffusion of drugs from C. Drug and cosmetic Packaging. Ophthalmic and aerosols. formulation and evaluation. Joseph D. Prodrugs. Griffin. [08] [08] [08] 89    . Packaging Engineering. Corrugated fibre board materials. chemical and biomedical engineering approach to achieve controlled drug delivery. 6. [08] [08] BOOKS RECOMMENDED: 1. Harburn. Unit-II 3. Medical Device Packaging Handbook.

Requirements of GMP. 5. Robinson and Vincent. Forms and maintenance of records in Pharmaceutical industry. Deasy. applications of process validation. Microencapsulation and Related Processes. nanoparticles. QUALITY ASSURANCE & VALIDATION Unit-I 1. etc. Targeted Drug delivery systems: Concept of drug targeting. 2. BOOKS RECOMMENDED 1. Polymers in Controlled Drug Delivery. 11. Ghosh. pulmonary colonic delivery. An Introduction to buccal. Quality assurance systems. Design of Biopharmaceutical Properties Through Produrugs and Analogs. Gutcho. Julian. methods in drug targeting. GLP. Unit-III 4. Drug Design: Facts or Fantasy. 7. Documentation. neosomes. Premamoy<’ Polymer Science & Technology”. liposomes.Unit-IV 7. Chien.Concepts in validation. Noxon. 3. Roiche. [08] [08] (G) GMP. environment etc Unit-IV 5. personnel. Unit-V 8. Preparation of documents for new drug approval and export registration. nasal. 10. Controlled Drug Delivery. ocular. Lisbeth. validation of manufacturing and analytical equipment. Basic concept of quality assurance. importance in therapeutics. containers. Sustained and Conrolled Drug Delivery Systems. CGMP. 9. Microencapsulation. pharmacosomes and erythrocytes. Advances in drug delivery systems. closures. Sources and control of quality variation.raw materials. 8. [08] Unit-II 2. 90    [08] [08] . 4. USFDA. Drug Delivery Systems. Novel Drug Delivery Systems.Protocols. drug immobilization techniques. 6. 3. Microencapsulation and Related Processes. Process validation in manufacturing dosage formulations. Jolles and Wooldbridge. WHO guidelines and ISO 9000 series. Illum & Davis. Robinson.

Garfield. 4. [08] PHAR-485 P Project on Elective   91    . OPPI. 2.GMP for Pharmaceuticals’. 7. Quality Assurance Principles for Analytical Laboratories. Quality Assurance. Sampling plans. 7. Tuckerman and Hitchings. 8. Willing. Pharmaceutical Process Validation. Florey. IPQC problems in pharmaceutical industries. Loftus and Nash. 6.” C. In process quality control tests. British Pharmacopoeia. BOOKS RECOMMEDED: 1. Good Manufacturing Practices for Pharmaceuticals. Sampling and operating characteristics curves.` 9. Manohar A.Unit-V 6. United States Pharmacopoeia. 3. Indian Pharmacopoeia. Analytical Profile of Drugs (All volumes). 5. Potdar.