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I M.B.B.S. Regulation - 2005


CONTENTS --------------------------------------------------------------------------SL.No. Description Pg.No. -------------------------------------------------------------------------------------1. 2. 3. Short Title and Commencement General Considerations & Teaching Approach Eligibility (1) Age Limit (2) Qualifying Examinations (3) Selection of Students (4) Eligibility Certificates 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Cut-off dates for admission Enrollment of Candidates Registration of Candidates Course of Study Commencement of the Course Curriculum Medium of Instruction Submission of Laboratory Record Note Books Working days in an academic year Internal Assessment 09 10 12 16 16 16 17 18 21 21 21 21 22 22 04 04

Attendance required for admission to examination 24 Regulations for condonation of lack of attendance 25

I MBBS Regulations 2005


:2: --------------------------------------------------------------------------SL.No. Description Pg.No. -------------------------------------------------------------------------------------16. “University Examinations’ (1) Commencement of Examination (2) Timing of Examination (3) Exemption in passed subjects (4) Carryover of failed subjects 17. 18. 19. 20. 21. Revaluation of Answer Papers Classification of Successful candidates Re-admission after break of study Migration / Transfer of candidates Curriculum – Syllabus for i) Anatomy ii) Physiology iii) Bio-chemistry Pattern of Examinations i) Anatomy ii) Physiology iii) Bio-chemistry Marks qualifying for a Pass i) Anatomy ii) Physiology iii) Bio-chemistry Community Medicine (1) Annexure I [Regulations 6] (2) Annexure II [Regulations 20 (iii)] (3) Annexure III [Regulation 20 (iv)] ********** 25 26 26 27 27 27 28 28

33 43 54


40 53 62


42 53 63 64 30 31 32

24. 25.

I MBBS Regulations 2005

Act. MEDICAL UNIVERSITY. the Standing Academic Board of the Tamil Nadu Dr.B.G. Medical University. These regulations are applicable to the students who are admitted to the course from the academic year 2005-06*.4 THE TAMIL NADU Dr.B. M.R. SHORT TITLE AND COMMENCEMENT: These regulations shall be called "REGULATIONS FOR THE M. held on 05-08-2005. 1987 (Tamil Nadu Act 37 of 1987). I MBBS Regulations 2005 .B.G.R.S. 2. Chennai.R. M. M. Medical University hereby makes the following regulations: 1. M. CHENNAI REGULATIONS FOR THE BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE COURSE In exercise of the powers conferred by Section 44 of the Tamil Nadu Dr.R. MEDICAL UNIVERSITY.G. CHENNAI”.G. GENERAL CONSIDERATIONS AND TEACHING APPROACH: (1) Graduate medical curriculum is oriented towards training students -------------------------------------------------------------------------------------------*XXIX S.A. DEGREE COURSE (NON-SEMESTER) 2005 OF THE TAMIL NADU Dr. The regulations framed are subject to modification by the Standing Academic Board from time to time.

Adequate exposure to such experiences. This has to be further intensified by providing exposure to field practice areas and training during the internship period. promotive. The aim of the period of rural training during internship is to enable the fresh graduates to function effectively under such settings. (4) The importance of the community aspects of health care and of rural health care services is to be emphasised. This aspect of education and training of graduates should be adequately recognised in the prescribed curriculum. I MBBS Regulations 2005 . should be available throughout in all the three phases of graduate medical education and training. curative and rehabilitative aspects of medical care. (2) With a wide range of career opportunities available today a graduate has a wide choice of career opportunities.5 to undertake the responsibilities of a physician of first contact who is capable of looking after the preventive. The training though broad based and flexible should aim to provide educational experience of the essentials required for health care in our country. To avail of opportunities and engage in professional activities the graduate shall endeavour to acquire basic training in different aspects of medical care. it is essential to provide adequate placement training tailored to the needs-of such services. (3) To undertake the responsibilities of various service situations.

6 (5) The educational experience should emphasize health and community orientation instead of only disease and hospital orientation or being concentrated on curative aspects. (6) Enough experience must be provided for self learning. To achieve this purpose the educational process should also be community based rather than only hospital based. The methods and techniques that would ensure this must become a part of the teaching-learning process. (7) The medical graduate of modern scientific medicine shall endeavour to become capable of functioning independently in both urban and rural environment. The importance of population control and family welfare planning should be emphasized throughout the period of training with the importance of health and development duly emphasized. As such all the basic concepts of modern scientific medical education are to be adequately dealt with. I MBBS Regulations 2005 . He/She shall endeavour to master the fundamental aspects of the subjects taught and all common problems of health and disease avoiding unnecessary details of specialization. (8) The importance of social factors in relation to the problem of health and disease should receive proper emphasis throughout the course.

ability to collect and analyse information and to correlate the facts. they are best taught in a setting of clinical relevance with hands on experience for the students to assimilate and make this knowledge a part of their own working skills. Students shall be encouraged to learn in small groups through sheer interactions so as to gain maximal experience through contact with patients and the communities in which the patients live. clarity of expression and independence of judgement. The history of Medicine with reference to the evolution of medical knowledge both in this country and in the rest of the world should form a part of this process.7 (9) Adequate emphasis is to be placed on cultivating logical and scientific habits of thought. (10) The educational process should be placed in a historical background as an evolving process and not merely as an acquisition of a large number of disjointed facts without a proper perspective. Every effort should be made to encourage the use of active methods related to demonstration and first hand experience. I MBBS Regulations 2005 . (11) Lectures alone are generally not adequate as a method of training and a means of transferring information and even less effective at skill development and in generating the appropriate attitudes. While the curriculum objectives often refer to areas of knowledge or science.


(12) The graduate medical education in clinical subjects should be based primarily on teaching in out-patient and emergency

departments and within the community including peripheral health care institutions. The out-patient departments should be suitably planned to provide training to graduates in small groups. (13) Clinics should be organized in small groups of preferably not more than 10 students so that a teacher can give personal attention to each student with a view to improving his skill and competence in handling of patients. (14) Proper records of the work should be maintained which will form a basis for the student's internal assessment. They should be available to the inspectors at the time of inspection of the college by the Medical Council of India. (15) Maximal efforts have to be made to encourage integrated teaching between traditional subject areas using a problem based learning approach starting with clinical. or community cases and exploring the relevance of various pre-clinical disciplines in both understanding and resolving a problem. Every attempt must be made to avoid compartmentalisation of disciplines so as to achieve both horizontal and vertical integration in different phases.

I MBBS Regulations 2005


(16) Every attempt is to be made to encourage students to participate in group discussions and seminars to enable them to develop personality, character, expression and other faculties which are necessary for a medical graduate to function either in solo practice or as a team member/leader when he begins his independent career. A discussion group should not have more than 20 students. (17) Faculty members should avail of modern educational technology while teaching the students. To attain this objective Medical Education Units/Departments should be established in all medical colleges for faculty development and providing learning resource material to teachers. (18)To derive maximum advantage out of this revised curriculum the vacation period of students in one calendar year should not exceed one month during the 4 ½ years Bachelor of Medicine and Bachelor of Surgery (MBBS) Degree Course. 3.. ELIGIBILITY (1) Age limit: No candidate shall be allowed to be admitted to the Medical curriculum of First Bachelor of Medicine and Bachelor of Surgery (MBBS) Degree Course until; he/she shall complete the age of 17

I MBBS Regulations 2005


years on or before 31 December of the year of admission to the course; (2) Qualifying examination: No candidate shall be allowed to be admitted to the First Bachelor of Medicine and Bachelor of Surgery (MBBS) Degree Course until he/she has passed a qualifying examination as under: (a) The Higher Secondary Examination or the Indian School Certificate Examination which is equivalent to 10+2 Higher


Secondary Examination after a period of 12 Years of study, the last two years of study comprising of Physics, Chemistry and Biology with English at a level not less than the core course for English as prescribed by the National Council for Educational Research and Training after the introduction of the 10+2+3 years educational structure as recommended by the National Committee on education;
Note: Where the course content is not as prescribed for 10+2 education structure of the National Committee, the candidates will have to undergo a period of one year pre~professional training before admission to the Medical Colleges.

OR (b) The Intermediate Examination in science of an Indian

University / Board or other


examining body with

Physics,Chemistry and Biology which shall include a practical test in these subjects and also English as a compulsory subject. OR

I MBBS Regulations 2005

OR (f) Any other examination which in scope and standard is found to be equivalent to the intermediate science examination of an Indian University/Board.11 (c) The Pre-professional/Pre-medical Examination with Physics. Chemistry & Biology and also English as a compulsory subject. Chemistry and Biology including a practical test: in these subjects provided the examination is a University Examination and candidate has passed 10+2 with English at a level not less than a core course. Chemistry and Biology including a practical test in each of these subjects and English. taking Physics. Biology and English. Chemistry. OR (d) The first year of the three years degree course of a recognized University. Chemistry.Sc. Chemistry and Biology. provided that he/she has passed the B. The Pre-professional/Pre-medical Examination shall include a practical test in Physics. with Physics. Examination with not less than two of the following subjects Physics. Examination of an Indian University. OR (e) B. I MBBS Regulations 2005 . Biology (Botany and Zoology) and further that he/she has passed the earlier qualifying examination with the following subjects Physics.Sc. after passing either the Higher Secondary School Examination or the Pre-University or an equivalent examination.

(3) (a) SELECTION OF STUDENTS : The Selection of students to medical college shall be based solely on merit of the candidates and for determination of merit. the integrated courses should be abolished. in the vocational stream are not eligible for admission to M.B. (iii) After the 10+2 course is introduced. the candidate must have passed any of the qualifying examinations as enumerated above at 3(2).12 Note: The Pre-medical course may be conducted either in a Medical College or in a Science College.S.Sc. I MBBS Regulations 2005 .B. (ii) Candidates who have passed the H. the following criteria be adopted: (i) In a state having more than one Board/examining body conducting the qualifying examination of where there is more than one medical college under the administrative control of one authority a competitive entrance examination should be held. course. (ii) To be eligible for competitive entrance examination. (i) The marks obtained in Mathematics are not to be considered for admission to MBBS Course.

C. Minimum of 55% of marks in Biology or Botany & Zoology taken together. No. Aggregate should not be less than 120 out of 200. M.C. B. Chemistry and Biology taken together at the qualifying examinations” : Sl. Minimum Eligibility Marks * Minimum of 60% of marks in Biology or Botany & Zoology taken together. 55% of marks in each of Physics and Chemistry. ---------------------------------------------------------------------------------------• XXVI SAB dt.13 (iii) *A candidate for admission to M.B. Community O.S. 16-12-2003 I MBBS Regulations 2005 .B. Degree Course must have obtained individual pass in English and the following marks in Physics. 60% of marks in each of Physics and Chemistry. 2.C. Aggregate should not be less than 130 out of 200. Minimum of 60% of marks in Biology or Botany & Zoology taken together. Aggregate should not be less than140 out of 200.B. 1. 3. 60% of marks in each of Physics and Chemistry.

B.C. S. Minimum of 40% of marks in Biology or Botany & Zoology taken together. degree course under All India Quota must have passed in the subjects of Physics. In respect of candidates belonging to Scheduled Castes.S. Schduled Tribes or other Backward classes. Aggregate should not be less than 80 out of 200. I MBBS Regulations 2005 .T.B. Chemistry & Biology (Botany & Zoology) taken together in qualifying examination be 40% instead of 50% as above with a pass in English./S. Biology (Botany & Zoology) and English individually and must have obtained a minimum of 50% marks taken together in Physics. 40% of marks in each of Physics and Chemistry. Chemistry and Biology (Botany & Zoology) at the qualifying examination as mentioned in clause (a) to (f) under Regulation 3 (2) above.14 4. Chemistry. (b) Selection of students under All India Quota: The following are the eligibility criteria for the candidates selected under All India Quota scheme:A candidate for admission to M. the marks obtained in Physics.

(ii) For SC/ST students – 40 % of the marks as stated above (2) The following guidelines shall be followed for admission to NRI students in Self-Financing Colleges: (i) Admission to the NRI seats may be made on the basis of the marks in the qualifying examination.( Ms.2006]. * (1) The marks fixed by Medical Council of India as indicated below shall be adopted as minimum eligibility marks for admission to MBBS/BDS/Para Medical Course under NRI Quota in Self-Financing Colleges (i) The candidates must pass Physics.22.) No: 137 Health and Family Welfare (MCA1) Department dated 14. Chemistry and Biology in the qualifying examination.12.15 C) Admission Procedure For NRI Quota Seats in Self Financing Colleges [G. (b) NRI Bank Account Pass Book of the financial supporter (c) Passport of the Financial Supporter (d) Nativity Certificate of the Financial Supporter (e) Evidence of payment of Development Charges of US $ 1000.08.O. (iv) Applicants for admission under NRI Quota shall not have completed 21 years of age as on the 1st of July of the respective academic year. Chemistry. (v) Candidate must furnish the Xerox copies of the following supporting documents:(a) NRI Status Certificate of the financial supporter issued by the Embassy of respective Country under their seal. -------------------------------------------------------------------------------------------------------------------* 32nd SAB dt. (ii) The candidates who are seeking admission under NRI Quota are exempted from appearing for the Tamil Nadu Professional Courses Entrance Examination. (iii) NRI financially supporting the candidate must be a blood relation such as Father/Mother/Brother/Sister/Uncle/Aunty only. Biology (Botany and Zoology) and English individually and obtain minimum of 50% of marks taken together in Physics.2006 I MBBS Regulations 2005 .

CUT-OFF DATES FOR ADMISSION * : The candidates admitted upto 30th September shall be registered to take up their I year examination during August of the next year and the next examination during February of the subsequent year. 4.06. There shall not be any admissions after 30th September even if seats are vacant.2006). 5.16 (4) Eligibility Certificate: Candidates who have passed any qualifying examination other than the Higher Secondary course examination conducted by the Government of Tamil Nadu shall obtain an eligibility certificate from the University by remitting the prescribed fee along with the application form before seeking admission to any one of the affiliated Medical Institutions.tnmmu. ENROLLMENT OF CANDIDATES*@ : The candidates admitted provisionally shall apply to the University for Enrollment within 7 days from the date of admission in prescribed -------------------------------------------------------------------------------------------------------------------* XXVI SAB dt.ac. 16-12-2003 @ No enrolment of candidates from the academic year 2006-07 onwards (31st Standing Academic Board dated:29. The application form and the details for obtaining Eligibility Certificate may be downloaded from the University website: www. I MBBS Regulations 2005 .in. All kinds of admissions shall be completed on or before 30th September of the academic year.

by the Affiliated Colleges. degree course in any of the affiliated Institution of this University shall register his / her name by submitting the prescribed application form for Registration duly filled along with the prescribed fee and a declaration in the format as in Annexure-I to the Academic Officer* of this University through the --------------------------------------------------------------------------------------------------------------* 31st SAB dt.Graduate course admission and (iii) a fee of Rs.B. which shall be downloaded from the University website (www.in) along with (i) provisional admission card issued by the College / Selection Committee. (ii) Eligibility Certificate for Non-Higher Secondary Course and other State candidates for Under. over and above permitted intake.S. if he/she does not satisfy the eligibility criteria for admission to the course concerned.tnmmu.ac. Enrollment will not confer any right on the candidate for registration with the University to take up the University Examinations.125/. 6.B.17 form. REGISTRATION OF CANDIDATES: A candidate admitted in M. Enrollment is made purely to ensure that the admission of the candidate is within the permitted intake for the academic year concerned and to check any excess admission. 29-06-2006 I MBBS Regulations 2005 .( or ) that may be prescribed by the authorities of the University from time to time.

Every student shall undergo a period of certified course of study extending over 4 1/2 academic years followed by one year of compulsory rotating internship. COURSE OF STUDY: (1).B.S. course for admission. (2). The period of 4 1/2 years is divided into three phases as follows: (a) PHASE-I (I MBBS)ONE YEAR consisting of Pre-clinical subjectsi) Human Anatomy. (b)PHASE-II (II MBBS)1 1/2 YEARS consisting of para clinical / clinical subjects. Besides 60 hours for introduction to Community Medicine including Humanities. 7. iii) BioChemistry and iv) Introduction to Community Medicine including Humanities. rest of the time shall be somewhat equally divided between Anatomy and Physiology plus Bio-chemistry combined (Physiology 2/3 and Bio-Chemistry 1/3).18 Head of the affiliated Institutions within 60 days from the cut-off date prescribed for M. ii) Physiology including Bio-Physics. --------------------------------------------------------------------------------------------------------------* 31st SAB dt.B. 29-06-2006 I MBBS Regulations 2005 . The first MBBS course shall commence on the 1st August of academic year*.

approximately equal time shall be allotted to Pathology. iii) Microbiology. The para-clinical subjects shall consist of :i) Pathology. The clinical subjects shall consist of all those detailed below in Phase III. I MBBS Regulations 2005 . Pharmacology. The clinical subjects to be taught during Phase II and III are : i) Medicine and its allied specialities. ii) Surgery and its allied specialities. teaching of para-clinical and clinical subjects shall be done concurrently. iv) Forensic Medicine including Toxicology and v) Part of Community Medicine. Microbiology and Forensic Medicine and Community Medicine combined Medicine). ii) Pharmacology.19 During this phase.Continuation of study of clinical subjects from Phase-II. iii) Obstetrics and Gynaecology and iv) Community Medicine. (1/3 Forensic Medicine and 2/3 Community (c) PHASE-III (III MBBS) TWO YEARS . Out of the time for Para-clinical teaching.

During clinical phase - I MBBS Regulations 2005 . After passing pre-clinical subjects. demonstrations.S. Radio-therapy etc. Tuberculosis and Chest. 1-1/2 years shall be devoted to para-clinical subjects. (approximately 240 teaching days) shall be occupied in the Phase I (Pre-clinical) subjects.Laryngology. Skin and Sexually Transmitted Diseases. etc. in various subjects. The Obstetrics & Gynaecology training will include Family Medicine.20 Besides clinical posting the rest of the teaching hours should be divided between didactic lectures. The training in Surgery and its allied specialities will include General Surgery. Family Welfare Planning. Radio- diagnosis. Phase II will be devoted to Para-clinical and clinical subjects. seminars. along with clinical postings. Dentistry. Infectious diseases etc. Psychiatry. group discussions etc.B. (3) THE PHASE I – I M. Ophthalmology. Orthopaedic Surgery including Physiotherapy and Rehabilitation. Anaesthesia. No student shall be permitted to join the Phase II (Paraclinical/clinical) group of subjects until he / she has passed in all the Phase I (Pre-clinical) subjects. Paediatrics. Oto-Rhino.B. The training in Medicine and its allied specialities will include General Medicine.

-------------------------------------------------------------------------------------------*XXVI SAB dt.21 (Phase III) pre-clinical and para-clinical teaching shall be integrated into the teaching of clinical subjects wherever relevant. 10. SUBMISSION OF LABORATORY RECORD NOTE BOOKS At the time of practical/clinical examination each candidate shall submit to the Examiners his/her laboratory note books duly certified by the Head of the Department as a bonafide record of the work done by the candidate. CURRICULUM: The Curriculum and the Syllabi for the course shall be as specified in these Regulations. 8. 11. 9. The practical record shall be evaluated by the concerned Head of the Department (Internal Evaluation) and the practical record marks shall be submitted to the University 15 days prior to the commencement of the theory examinations. MEDIUM OF INSTRUCTION : English shall be the medium of instruction for all the subjects of study and for examinations. 16-12-2003 I MBBS Regulations 2005 . COMMENCEMENT OF THE COURSE :* From 1st August of the Academic year.

12. In respect of failed candidates the marks awarded for records at previous examinations will be carried over to the next examinations. handwritten. INTERNAL ASSESSMENT: a) The Internal Assessment should be done once in three months. At the end of 3 months – First Internal Assessment At the end of 6 months – Second Internal Assessment One month prior to the University Examination .22 The candidate may be permitted by the examiners to refer to the practical record book during the practical examination in the subject of Biochemistry only. cyclostyled or printed guides are allowed for reference during the practical examinations. 13.Third Internal Assessment I MBBS Regulations 2005 . No other materials. WORKING DAYS IN AN ACADEMIC YEAR: Each academic year shall consist of not less than 240 working days. If a candidate desires he/she may be permitted to improve his/her performance by submission of fresh records.

2005 ** XXIX SAB dated:05. It comes into effect from August 2006 examination onwards.2005 I MBBS Regulations 2005 .A.23 The Internal Assessment consists of the following points: a) Theory b) Practical/Clinical c) Viva Voce All the details regarding Internal Assessment should be sent to the University at the end of January. examination for the knowledge of the students. ** ----------------------------------------------------------------------------------------------------------* SAB dated:28.08. Practical/Clinical & Oral should be added and aggregate must be taken and sent to the University as Internal Assessment Marks. March & May for 100 marks and the aggregate of final Internal Assessment marks at the end of June for 80 marks by the Head of the Department of the subject concerned through the Dean/Principal of the Colleges.12.* The average of the Theory. The aggregate of Final Internal Assessment Marks submitted at the end of June for 80 marks shall be taken by the University as Internal Assessment Marks for permitting the candidates to sit for the examinations. 35% of minimum marks is necessary to appear for the examinations. The Internal Assessment marks must be exhibited periodically on the Notice Board after completion of the I.

I MBBS Regulations 2005 . 14. ATTENDANCE REQUIRED FOR ADMISSION TO EXAMINATION : a) No candidate shall be permitted to anyone of the parts of MBBS Examinations unless he/she has attended the course in the subject for the prescribed period in an affiliated institution recognised by this University and produces the necessary certificate of study.2003. -------------------------------------------------------------------------------------------------------------------*XXVI S. be considered for improvement. dated 16. attendance and progress from the Head of the Institution.A.24 b) A failed candidate in any subject should be provided an opportunity to improve his/her internal assessment marks by conducting a minimum of two examinations in theory and practical separately and average. c) The internal assessment marks (both in written and practical taken together) should be submitted to the University endorsed by the Head of the institutions fifteen days prior to the commencement of the theory examinations.B. d) A candidate should obtain a minimum of 35%* of marks in internal assessment in a subject to be permitted to appear for the University examination in that subject.12.

August 1st / February 1st. 16. UNIVERSITY EXAMINATIONS* (1). e) Attendance earned by the student should be displayed on the Notice Board of the College at the end of every 3 months and a copy of the same should be sent to the University and parents of the student concerned. -------------------------------------------------------------------------------------------*XXVI S. I MBBS Regulations 2005 . 15.12.B.25 b) A candidate is required to put in minimum 75% * of attendance in both theory and practical / clinical separately in each subject before admission to the examination. c) A candidate lacking in the prescribed attendance in any one subject in the first appearance shall be denied admission to the entire examinations.A. d) Failed candidates who are not promoted to the next phase of study are required to put in minimum 75% of attendance during the extended period of study before appearing for the next examination.2003. dated 16. REGULATIONS FOR ATTENDANCE : CONDONATION OF LACK OF There shall be no condonation of lack of attendance for the course. COMMENCEMENT OF EXAMINATION : a.

If the date of commencement of the examination falls on a public holiday. Theory examinations not to be held on Saturdays and Sundays. (b) Phase II .26 b. Timing of Examinations: (a) Phase I . the next working day will be the date of commencement of examination.professional examination: At the end of 1 ½ years from the commencement of Phase II. I MBBS Regulations 2005 . (c) Phase III – Part I professional examination: At the end of one year of Phase III. Exemption in passed subjects: Candidates who fail in an examination but obtain pass mark in any subject. (3).professional examination: At the end of one academic year. shall be exempted from re-examination in that subject. (d) Phase III – Part II professional (Final Professional) examination: At the end of 2nd year of Phase III. (2).

2006 I MBBS Regulations 2005 . 17. (b) A student who fails in the II MBBS professional examination shall be permitted to carry the failed subjects to Phase III of the M. however passing of III MBBS Professional (Part I) is compulsory for being eligible to appear for III MBBS Professional. retotalling is only allowed in the failed subjects.06. 18. Carry over of failed subjects: (a) Passing in First MBBS Professional examination is compulsory before proceeding to Phase II training.B. CLASSIFICATION OF SUCCESSFUL CANDIDATES:** Distinction will be awarded to successful candidates who -----------------------------------------------------------------------------------------------------------------** Deleted 31st SAB dated:29. However. REVALUATION OF ANSWER PAPERS: There is no provision for revaluation of answer papers.S. (Part II) examination. Passing in II MBBS Professional examination is compulsory before entering Part II of Phase III (final year) of the course.27 (4).B. course but shall not be allowed to appear in III MBBS Professional Part I examination unless he/she passes all the subjects of the II MBBS Professional examination. (c) Passing in III MBBS Professional (Part I) examination is not compulsory before entering for Part II training.

20. provided the following criteria are fulfilled. RE-ADMISSION AFTER BREAK OF STUDY: As per the procedure laid down in a common Regulation for all the Under-graduate and Post-graduate courses of this University.B. the period being counted from the date of declaration of results. ii) The applicant should have passed first professional M. I MBBS Regulations 2005 . practical and viva alone. i) Both the Colleges are recognised by the Medical Council of India.28 secure 75% marks or more as a course aggregate in the first appearance taking University theory. However. 19. MIGRATION / TRANSFER OF CANDIDATES: Migration from one recognised Medical College to another recognised Medical College is not a right of a student.B. migration of students from one recognised medical college to another recognised medical college within India may be considered by the Medical Council of India only in exceptional cases on extreme compassionate grounds.S. examination. (Routine migrations on other grounds shall not be permitted). iii) The application for Migration complete in all respects along with the Proforma as in Annexure-II is submitted to all authorities concerned within a period of one month of passing the first professional Bachelor of Medicine and Bachelor of Surgery (MBBS) examination.

iii) The number of student migrating/transferring from one medical college to another medical College during one year will be kept to the minimum so that the training of the regular students of that college is not adversely affected. b) Illness of the candidate causing disability. The number of students migrating/transferring from or to any one medical college shall not exceed the limit of 5% of its sanctioned intake in one year. iv) Issue of N. NOTE : (i) Migration during clinical course of study will not be considered by the University. *** I MBBS Regulations 2005 . (ii) All applications for migration will be referred to Medical Council of India by college authorities. The affidavit should be duly certified by the Dean of the College concerned and the Registrar of the concerned University to which transfer is sought.C.29 iv) The applicant must submit an affidavit (as in Annexure-III) duly sworn in before the Ist class Magistrate stating that he/she will pursue 18 months of prescribed study before appearing for the II professional Bachelor of Medicine and Bachelor of Surgery (MBBS) examination at the transferee Medical College. for all Migrations/Transfers are subject to the approval of the Vice-Chancellor. c) Disturbed conditions declared by Government in the Medical College area. v) The following compassionate grounds shall be considered for the purpose of Migration.O. The University will not consider request for migrations without the approval of the Medical Council of India. a) Death of a supporting guardian.

/ Countersigned / Dean / Principal / Director.G. Residing at …………………………………………………………………… and admitted to in I year of …………………………… (Name of the course/ U. Chennai for the ………… (course) including regulations for re-readmission after the break of study. (Name of the College) do hereby solemnly affirm and sincerely state as follows : I declare that I shall abide by the rules and regulations prescribed by the Tamil Nadu Dr. G. Medical University.30 ANNEXURE – I REGULATION 6 DECLARATION I ………………………………………………………………………. M. R.) at ………………………………………………………………….. (Office date seal) I MBBS Regulations 2005 ./P. Son of / Daughter of …………………………………………………………. Date : Signature of the candidate.G.

9) a) Reasons for migration in brief (Date)___(Month)___(year)____ (Date)___(Month)___(year)____ (Date)___(Month)___(year)____ (date of issue) (date of issue) (date of issue) (date of issue) Yes/No b) Whether proof for the reasons enclosed Yes/No 10) Whether Bank Draft of Rs. duly Sworn before I Class Magistrate containing an undertaking that “I will study for full 18 months of II Phase of MBBS course in transferee Medical College.(non-refundable Migration fee) in favour of the Secretary.________________________________________________from _________________ Medical College.31 ANNEXURE-II REGULATION 20(iii) PROFORMA Migration of Mr/Miss. ______________to ______________________ Medical College ____________________.500/. 2) Date of Passing I MBBS University Exam 3) Date of application 4) NOC from relieving college (enclosed) 5) NOC from relieving university (enclosed) 6) NOC from receiving college. New Delhi. Yes/No Payable at New Delhi enclosed. (enclosed) 7) NOC from receiving University (enclosed) 8) Whether affidavit. Medical Council of India. 1) Date of admission in I MBBS course. 11) Permanent Address:- 12) Postal Address:SIGNATURE I MBBS Regulations 2005 . Before appearing in the II Professional University examination is enclosed”.

The above facts are true.B.Medical College IDENTIFIED BY ME Countersigned and certified that the above facts are true Registrar Tamil Nadu Dr. Photo Attested by First Class Magistrate Deponent Signature DEAN --------------------------.B. I am arranging to migrate from ___________ Medical College _____________ to ______________ Medical College. ______ That I hereby give my consent and undertaking to pursue my study for the full 18 months of II phase of M.32 ANNEXURE-III REGULATION 20 (iv) SWORN AFFIDAVIT I. Solemnly affirmed at _________ on This day of ________________ And signed his/her name in my presence.B. _____________ and that on the strength of this undertaking. II M.Medical University.B.S.G.M. That I am at present studying II year MBBS in ________________Medical College./D/o. Certified that the above facts are true. ____________________________.________________ aged about _____ years and residing at _________________________________________________ do hereby solemnly affirm and sincerely state as follows: 1.S. Chennai-32 I MBBS Regulations 2005 . __________ before appearing for II professional Bachelor of Medicine and Bachelor of Surgery (MBBS) examination at the ______________ Medical College. course in ________________ Medical College. ___________. 2.student S/o.R.

(d) demonstrate knowledge of the basic principles and sequential development of the organs and systems. recognise the clinical stages of development and the effects of common teratogens. (b) identify the microscopic structure and correlate elementary ultra structure of various organs and tissues and correlate the structure with the functions as a prerequisite for understanding the altered state in various disease processes. clinically relevant interrelationships. stress shall be laid on basic principles of the subjects with more emphasize on their applied aspects.33 CURRICULUM I M. ANATOMY Pre-Clinical Subjects – Phase – I: In the teaching of these subjects.B. He/She shall be able to explain the developmental basis of the major variations and abnormalities.B.2005 . HUMAN ANATOMY (i) Goal: The broad goal of the teaching of undergraduate students in Anatomy aims at providing comprehensive knowledge of the gross and microscopic structure and development of human body to provide a basis for understanding the clinical correlation of organs or structures involved and the anatomical basis for the disease presentations. (c) comprehend the basic structure and connections of the central nervous system to analyse the integrative and regulative functions of the organs and systems. (ii) Objectives: (A) Knowledge: At the end of the course the student shall be able to: (a) comprehend the normal disposition. I MBBS Anatomy Syllabus . functional and cross sectional anatomy of the various structures in the body.S. He/She shall be able to locate the site of gross lesions according to the deficits encountered.

(e) understand clinical basis of some common clinical procedures i.2005 . kidney biopsy etc. student shall be able to comprehend the regulation and integration of the functions of the organs and systems in the body and thus interpret the anatomical basis of disease processes. (C) Integration: From the integrated teaching of other basic sciences.B. (c) understand the principles of karyotyping and identify the gross congenital anomalies. Prosected specimens could replace the rest of the dissections. intramuscular and intravenous injection. GENERAL ANATOMY : The word "Anatomy" denotes "Applied Anatomy"* Descriptive terms General features and classification of bones General features and classification of joints General features and classification of tissues General features of muscle and fascia General features of nerves and Organisation of nervous tissue GROSS ANATOMY Dissections of important areas to be done.e. 05-06-2002 I MBBS Anatomy Syllabus . (a) identify and locate all the structures of the body and mark the topography of the living anatomy. lumbar puncture. Interpretation of plain and contrast X-rays. (d) understand the principles of newer imaging techniques like Ultra sound.34 (B) Skills: At the end of the course the student shall be able to. (b) identify the organs and tissues under the microscope. Computerised Tomography Scan. M.S ANATOMY SYLLABUS The course in Human Anatomy is to provide an understanding of the structure of the human body as a foundation for the scientific study and practice of medicine.B. -------------------------------------------------------------------------------------------------------------------------------* XXIII SAB dt.

Course and Termination of vessels Important relations and distribution.Greater and lesser sacs Peritoneal ligaments. Peritoneal cavity.2005 . Knowledge of lymphnodes. UPPER AND LOWER EXTREMITIES Muscles Joints --Names. Sub-diaphragmatic spaces Pelvic floor and Ischio-rectal fossa Basic knowledge of perineal spaces Name. Nerve supply and Action Names. Course and Termination of nerves Root value. Muscles Responsible Equal emphasis to be given to all joints of the extremities Vessels and Nerves -Commencement. Posterior Abdominal wall. areas of drainage Lymphatics -- Emphasis on important areas of venous and lymphatic drainage OSTEOLOGY Names of bones and Side identification. relevant and necessary applied and clinical aspects to be told and emphasized upon. Position. Essential attachments. Parts and attachments. Types of joints. Location. Blood supply. Important Relations. Important centers of ossification.35 Detailed origin and insertion of muscles to be replaced by essential attachments and emphasis to be placed on the understanding of the function. Inferior venacava Sacrum and Coccyx Features of Typical and Atypical lumbar vertebrae Bony Pelvis – Sex determination & Diameters Viscera -- OSTEOLOGY -- I MBBS Anatomy Syllabus . Growing ends. Commencement. Blood supply. Inguinal canal. Nerve supply. relations and distribution. Histology and Microstructure Portal vein and Porta-systemic Anastomosis Important arteries. In all areas. ABDOMEN AND PELVIS : Abdominal wall -Anterior Abdominal wall. Important peritoneal and other Relations. Movements.

Outflow of ANS and distribution Names & Location of bones of skull. Eyeball.2005 Brain -- . Names and Types of joints of Thorax. Palate. Organs of Hearing & Equilibrium The blood vessels and lymphatics of Head And Neck Cranial nerves and plexuses Ganglia.36 THORAX : Thoracic cage -Walls of thorax. Bony fossae Features of typical & atypical cervical vertebrae Cranial cavity Other areas --- Vessels and Lymphatics -- Nerves -- Autonomic Nervous System OSTEOLOGY BRAIN AND SPINAL CORD : Spinal cord -Spinal cord & Meninges Parts & Tracts of spinal cord Blood supply Brain & Meninges Blood supply Parts of brain and functional components I MBBS Anatomy Syllabus . Para-nasal air sinuses. Tongue. Mediastinum – sub divisions. boundaries and Contents (including Heart and Pericardium) Lungs and Pleura Diaphragm OSTEOLOGY -- Features of typical and atypical thoracic vertebrae Features of typical and atypical ribs Features of sternum HEAD AND NECK : Scalp & Neck -Scalp Face Sub-occipital Triangle Anterior & Posterior Triangles of Neck Structures in the neck Cranial fossae and structures related Duramater and dural venous sinuses Parotid region Temporal and Infra-temporal fossae Sub-mandibular region Mouth. Orbit. Pharynx. Larynx. foraminae. Bony cranial cavity – sub divisions. Nose and nasal cavity.

37 Base of brain. I MBBS Anatomy Syllabus . Eye lid and Parts of eyeball. Internal ear. Connective tissue. Embryonic period. Spermatogenesis. Basic Teratology. Mid brain. Salivary glands & Gastro-intestinal system Urinary system Reproductive system (male & female) Endocrine system. Palate. EMBRYOLOGY : General Embryology Oogenesis. Brachial apparatus Endocrine system Vertebral column Parts of neural tube & derivatives Visual and auditory apparatuses Outline of development of limbs HISTOLOGY : General Histology Cell. Cerebellum. Amnion. Spinal cord. Olfactory epithelium. Placenta. Diencephalon. CNS -. Bone. Nerve ganglia. Cerebrum. Cerebellum. Glands. Hind brain. Cartilage. Taste buds. Mid brain. Pons. Tongue. Umbilical cord Organogenesis. Vascular system. Twinning Special Embryology Gastro-intestinal system and spleen Urinary and genital systems Diaphragm Heart & Aortic arch derivatives Respiratory system Face.2005 . Nervous tissue Lymphoid tissue. Muscle. Epithelia. Fertilization Bilaminar and Trilaminar germ discs. Skin and its appendages Special Histology Respiratory system. Muco-cutaneous junctions.Medulla. Cerebrum.

Kidneys and Abdominal part of ureter. Chromosomal aberrations (Numerical & Structural). Internal jugular vein. SM of Common carotid artery. Structure of gene.Principle of X-ray . Facial artery on the face. 6 weeks 5 weeks 10 weeks 3 weeks 11 weeks 4 weeks ------------TOTAL 40 weeks ------------I MBBS Anatomy Syllabus . Root of mesentery. IC junction. Duodenum Pancreas. Nasion.38 GENETICS : Structure of chromosome. Larynx. Sex linked inheritance. Thyroid cartilage. Single gene inheritance. Liver.2005 . Cricoid Cartilage Thyroid gland. Pterion. Karyotyping. Autosomal Inheritance.CT scan at T3. Important dural venous sinuses Central sulcus. fundus of Gallbladder. SM of important vessels and nerves. Spleen. Valves Pleura and Lungs Major vessels Vertebral levels of Hyoid bone. Mutation. TEACHING SCHEDULE : Introduction General Anatomy General Embryology General Histology Upper extremity Lower extremity Abdomen and Pelvis Thorax Head and Neck Brain & Spinal cord 1 week Teaching Hours 650 Hrs. Sylvian sulcus Thorax Head & Neck Brain RADIOLOGICAL ANATOMY: X-rays . Abdominalaorta And Inferior venacava Borders of Heart. Parotid gland and duct Palatine tonsil Inion. Base of Appendix. Regions and Planes of Abdomen.Principles of Ultrasound and CT scan . T4 and L1 levels.Plain and Contrast X-rays . SM of superficial and deep inguinal rings SM of Stomach. SURFACE ANATOMY : Extremities Abdomen Bony landmarks.

Importance of the venous drainage of Lower Extremity and varicose veins. c. 2.2005 . presentation. Example : Leprosy patients with nerve lesions of the Upper Extremity at the end of the study of Upper Extremity. Example : a. At the end of a region students be given cases of that region for study. To stress the importance of clinical and applied Anatomy. Anatomical basis of hernia and repair. EVALUATION INTERNAL ASSESSMENT Theory Practicals Records 40 marks * 30 marks 10 marks * -----------TOTAL 80 marks ------------ UNIVERSITY EXAMINATION PATTERN: THEORY TWO PAPERS of 3 (three) hours duration 100 marks each. Anatomical basis of transplant. b. analysis and discussion.39 Horizontal Integration : The preclinical departments together plan the Horizontal Integration. 1. pertaining to the region covered. 3. Display study questions on the notice board weekly. PAPER I : General / Applied Anatomy General Embryology General Histology Upper and Lower extremities Abdomen and Pelvis (along with essential Embryology and Special Histology) ---------------------------------------------------------------------------------------------------------• 30th Meeting of SAB held on 28/12/2005 I MBBS Anatomy Syllabus . Invite clinicians to give guest lectures and demonstrations to highlight the anatomical basis of the clinical conditions.

. Gross Spotters 15 Histology Spotters 15 2 x 15 = 30 Discussion 10 2 x 15 = 30 Discussion 10 40 Marks } }* 40 Marks Gross Spotters . Each spotter may have two or more structured questions. 2 } -----15 ------ I MBBS Anatomy Syllabus . 3 + 1 } } …... 2 …….40 PAPER II : Thorax Head and Neck Brain (along with Essential embryology and Special Histology) PATTERN OF QUESTION PAPER : ** Essay Questions Short Notes Short Answer Questions 2 x 15 Marks = 30 Marks 10 x 5 Marks = 50 Marks 10 x 2 Marks = 20 Marks ------------Total = 100 Marks -------------80 Marks* 30 Marks } } 10 Marks } }* 30 Marks } } 10 Marks } PRACTICAL EXAMINATION HISTOLOGY Spotters Discussion General 1 ] Special 1 ] -Spotters Discussion UL/LL/ABD HN/Br/Tho GROSS ANATOMY 1} 1} PRACTICAL : Two mark for each spotter and two minutes per spotter. 2 ….2005 . 2 } }* } } } ….Distribution Upper Extremity Lower Extremity Thorax Abdomen & Pelvis Head & Neck Brain & Spinal Cord ……. 2 + 1 } * } …..

** MCQ’s withdrawn from August 2008 onwards – 35th SAB held on 20. VIVA EXAMINATION : Osteology………………………………………………………….5. Marks are awarded for identification as well as discussion ).08. Radiology Surface Marking Embryology(including Karyotypes) Total 10 10 10 10 ---------40 Marks ---------- MARKS QUALIFYING FOR A PASS 50% in Theory 50% in Theory including Viva 50% in Practical 35% in I. Grand Total = = = = : 100/200 120/240 40/80 28//80 ---------200/400 ------------ * XXIX SAB held on 05. PRACTICAL EXAMINATION: A maximum of 25 candidates per day of practical examination is desirable.2005 from August 2006 onwards.A.2008 I MBBS Anatomy Syllabus .Distribution : General Histology Special Histology 3 } } * } 12 ----15 ----(Spotters should not be pre arranged.2005 .41 Histology Spotters .

B. (b) SKILLS: At the end of the course the student shall be able to: (1) conduct experiments designed for the study of physiological phenomena. – Syllabus .Physiology . (5) list the physiological principles underlying pathogensis and treatment of disease.43 I M. (B) BIOPHYSICS (a) GOAL AND OBJECTIVES: The broad goal of teaching Biophysics to undergraduate students is that they should understand basic physical principles involved in the functioning of body organs in normal and diseased conditions. (2) interpret experimental/investgative data. PHYSIOLOGY (2) HUMAN PHYSIOLOGY INCLUDING BIOPHYSICS (A) (i) PHYSIOLOGY GOAL: The broad goal of the teaching of undergraduate students in Physiology aims at providing the students comprehensive knowledge of the normal functions of the organ systems of the body to facilitate an understanding of the physiological basis of health and disease.B. (c) INTEGRATION: At the end of the integrated teaching the student shall acquire an integrated knowledge of organ structure and function and its regulatory mechanisms. (3) elucidate the physiological aspects of normal growth and developlment.S.S. (3) distinguish between normal and abnormal data derived as a result of tests which he/she has performed and observed in the laboratory. (4) describe the physiological response and adoptation to environmental stresses. I M.B.B. (2) assess the relative contribution of each organ system to the maintenance of the milleu interior. (ii) OBJECTIVES: (a) KNOWLEDGE: At the end of the course the student shall be able to: (1) explain the normal functioning of all the organ systems and their interactions for well coordinated total body function.

Physical principles governing flow of blood in heart and blood vessels.) Electromyogram (E.B. Cell membrane. I M. Excitability-strength duration curve.S. organelles. 5. ECF and ICF composition.44 Total time for teaching Biophysics Out of which : 5 hours 3 hours 1 hour 1 hour 1) Didactic lectures : 2) Tutorial/group discussion : 3) Practical : (b) TOPIC DISTRIBUTION: (1) Lectures: (i) (ii) (iii) Physical principles of transport across cell membrance and across capillary wall. contraction and relaxation of skeletal. Nervous tissue – Neurons and neuroglia-cell types : Myelination. Histophysiology of different types of epithelial.B. Neurotransmitters.G.Physiology .C. Muscle : Structure innervations. (3) Practicals: Demonstration of: (a) (b) (c) (d) Biopotential on oscilloscope Electroencephalogram (E. Generation and propagation of nerve impulse. Also Physical principles governing flow of all in air passages. adipose. – Syllabus . Body Water. excitation. GENERAL PHYSIOLOGY Must Learn : 1.) Electrocardiogram (E.G. Nice to Know : 1. Transmembrane electrical potential. their receptors. Physical and chemical properties of water. neurotransmitters. 3.E. Biopotentials. receptors & functions. Synapse. nucleus. 4.) SYLLABUS OF PHYSIOLOGY THEORY 1.G. Intercellular connection and matrix. (a) Division of the Autonomic Nervous System – their neurons. cartilage and bone tissues. 2. Transport across cell membrane. (2) Tutorial/group discussion: on the topics covered in didactic lectures. smooth and cardiac muscle. Types of nerve fibres of somatic sensory and motor nerves.M. fibrous.

6. 6. Blood volume. TLC & DLC. Diarrhoea. formation. Psychosomatic illness. Nice to know : 1. 4. Intestinal colic. Interleukins. Digestion and absorption in the small intestine. count. Dysphagia. – Syllabus . Bleeding Time. Malabsorption. Degeneration and regeneration of nerve fibres. skeletal muscle fibre types – Effect of exercise on muscles. Nice to Know : 1. defecation. 4. control of secretion. 3. Heart burn. circulation. Enteric Nervous System. Haematological indices. Thrombocytes – Structure and function. Erythrocytes – Structure. Muco physacharides and protein in matrix of connective tissues. Functional classification of plasma proteins. Physiological anticoagulants. Deglutition. Pancreatic juice – mode of secretion. Types of muscular contraction. Embolism. 4. Pancreastatin. 5. 2. Cholagogues. Lymph – Formation. Purpura. control of salivation. Choleretics. Lymphoedema. DIGESTION MUST LEARN 1. change in stored blood. 4. Functions of liver. gall stones. composition of hepatic and gall bladder bile. Motility of Enteron. Frank Starling’s Law. 6. Nernst equilibrium potentials. 8. Function of the colon – motility. function lymph nodes. Paralytic ileus. 7. destruction. Effect of haemorrhage and IV fluids on volume. Clotting time. Spleen – Structure and functions. Role of Vit. Effect of mismatched blood transfusion. Plasma expanders. Composition and functions of saliva. 7. haematocrit. prophylaxis. Minor blood group systems. 3. Coagulation of Blood. Crypts of Lieberkuhn composition and function of succus entericus. Obstructive jaundice. 3. Gastric motility and secretion – Control. Antibody and complement. 5. 5. Fibrinolysin. classification of anaemia. Digestion and Absorption in the stomach. innervation and blood supply. Endogenous pyrogen. BLOOD AND LYMPH : Must Learn : 1. formation. Coagulation defects. preload and after load. composition of faeces. 5. Plasmapheresis. Composition of plasma. Minor GI I M.Physiology . organization of clot.B. absorption. Emptying of gall bladder.B. functions. 3. 5. Histocytic system. Haematocrit. intestinal obstruction. 2. K. Effect of Vasomotor on lymph flow. fate. specific gravity and viscosity of blood. II. Plasma cells. 6. composition and functions. enterohepatic circulation. Mastication : Salivary glands and von Ebner’s glands. 4. Management of peptic ulcer. Tyrpsin inhibitor. ABO and Rh blood groups – compatibility. Monokines. Biliary colic. metabolism. in vitro and in vivo anticoagulants. Bile salts. Experimental evidence for phases of gastric secretion. Achylia and hyperacidity. musculature. Functions. count. Oedema.S. 7. other lymphoid tissue. 3. 2. formation. Vomiting. 2. Goldman constant field equation. Primary Haemostatis. Functional anatomy of the alimentary tract – glands. 8. Xerostomia. Thrombosis. secretion. Duodenal mucosa. Achalasia cardia. Immunity. III.45 2. Dumping syndrome. Leucocytes – Classification.

4. 8. Proximal tubular events – Reabsorption of Bicarbonate and glucose. pulmonary. Nephron – types. Action potential in atrial and ventricular muscle – ionic basis. 2. Dyschezia. hairgrowth cycle. cutaneous circulation. Role of Counter current mechanism in creating and maintaining medullary osmotic gradient. pigmentation. Megacolon. 3. Baroreceptors. Pacemaker potential.46 hormones. 6. Glomerular filtration. Nice to Know : 1. Venous Return and Cardiac Output – Values and distribution of output – Factors affecting and regulation of output. 6. Constipation. Urine concentrating mechanism – action of vasopressin. cholinergic sympathetics. vasomotor center – short term and long term regulation of BP. sebaceous secretion. I M. Action of Parahormone. Tubuloglomerular feedback. 5. Artificial kidney. their control. Micturition. Tubular load. cerebral. cavities. 9. Arterial pulse and jugular venous pulse. Systemic arterial blood pressure – values. Filling of bladder – cystometrogram. Reabsorption of Nephric filtrate. IV. Uretic colic. Hydronephrosis. 4. Types of hair. Skin – Functions. Starling’s Law of the heart – Effect of preload and after load. Origin and spread of cardiac impulse. Plasma Clearance. Peculiarities of Renal circulation. Motility in ureters. Micro circulation – Vasomotion – formation and absorption of interstitial fluid – Local regulation of blood flow. 4. Role of kidney in homeostasis of electrolyte concentration and acid base balance. Colitis. cutaneous receptors. Diluting segment of nephron. Dendritic. Glucose absorption curve. V. 7. 7. 8.S. Starling forces in the Malpighian corpuscle. 3. 2. Resistance to blood flow. Action of ANP and BNP and Adrenomedullin. 6. heart sounds. Nerve supply to heart – control of heart rate. Heart as a pump – cardiac cycle – phases and events. Distal tubular events – Action of Aldosterone. EXCRETION : Must Learn : 1. coronary. CARDIOVASCULAR SYSTEM Must Learn : 1.Physiology . factors determining.B. Regional blood flow. 7. Function anatomy of kidney and urinary tract. 8. Water diuresis.B. Langerhans cells. 7. 5. osmotic diuresis. Juxtaglomerular Appratus. sinus arrhythmia. sweat glands . Splanchnic and cutaneous circulations. Renal threshold. Diabetes insipidus. Measurement of GFR and RBF. 3. Properties of cardiac muscle and conducting tissue of the heart. parts. – Syllabus . 5. Cardiovascular changes during exercise. Alpiecia. Types of blood vessels – pressure gradient in circulatory system. Electrocardiography – Principle – 12 classical leads – ECG tracing in Lead II. Types of abnormal bladder. glycosuria. Dialysis. Transfer maximum. Plasma load. Heterogencity of nephrons. 2.

Artificial pacemaker. Ventilation. 3. Pressure and volume changes in ventricles. Haldane effect. commissures. Types of hypoxia. Effect of ions and drugs on heart. CENTRAL NERVOUS SYSTEM : Must Learn : 1. 8. 2. 2. Diffusion coefficient and capacity. Non-respiratory functions of lung. I M. 6. Effect of gravity and posture on arterial B. aviation and space travel on CVS. VI. Foetal Hb. Respiratory adjustments in disease states. Bell-Magendie law. Descending tracts of spinal cord – Upper motor neurons. neuronal circuitry in the cord. Cardiac catheterization. Mechanism. 4. 4. physiological shunt. liquid breathing. Efferent control. 5. congenital heart disease. Correlation of ECG tracing with phases of cardiac cycle and phase of action potential. 9. cyanosis. Energy sources of cardiac muscle. Cerebral cortex – layers. VII. Bohr effect. Foetal circulation. types of fibres in white matter. Grouping of sensory nerve fibres.failing heart. 4. Airway resistance.S. connection and function. Physiological effects of ascent to high altitudes – acclimatization. Nitrogen narcosis. generator potential. Brain stem – Location and function of different centres. Nice to Know : 1. RESPIRATION Must Learn : 1. V-Q ratio. Threshold stimulus. 6.B. respiratory tract and paranasal air sinuses. Hb-O2 dissociation. Hypotensive shock. Regulation – Chemoreceptors. Functional Anatomy of the thoracic cage. Asthma. Changes during muscular exercise. 2. oxygen therapy. 8. lungs. 2. perception and cognition. functions. Motor units. Hamburger phenomenon. Dysbarism. III to XII cranial nerves. Spirometric volumes and capacities. 5. chronoaxie. Spinal reflexes – Reciprocal inhibition. Effects of high altitude.B. 3. Diffusion : Composition of atmospheric and alveolar air. Estimation of cardiac output. 4. Functional map of cortex. Thalamus – Nuclei. Muscle tone. . Bronchial tone. Respiratory membrane.P. connections. 5. 7. Bryle’s law in ventilation. 5. 3. Transport of O2 and Co2 in blood and tissue fluid. Haemodynamics of blood flow. Compliance. Important vasodilators and vasoconstrictors. 3. their pathways & lesions. Pathways for different modalities of somatic sensation. Sensory receptors – Classification. Centres. partial pressures of gases in alveoli and blood. Control of muscle tone and voluntary movements. Asphyxia. emphysema and pulmonary oedema. power of muscles. 6. Hierarchial organization of CNS. Muscles of respiration. 6. – Syllabus . Surfactant.47 Nice to Know : 1. ARD Syndrome. dead space. Diffusion in fibrosis. Hypertension. their . Ascending tracts of spinal cord. 7. Inter-hemispheric communications. morphology.Physiology . Parts of the brain and spinal and – Morphology.

Reward and punishment areas of brain. Neuronal circuitry and information processing. Hydrocephalus. Epilepsy. 7. visual pigments. Disorder of sleep. Retina – layers. Neuronal circuitry and information processing. visual pigments. Types of ganglion cells and optic nerve fibres. 2. Blinking. Functional anatomy of the eyeball and adnexa. Encephalization. tests. photoreceptors. 9. Decerebrate rigidity. 3. ECG. Eustachian tube. Speech.S. 6. visual field. Cerebrospinal fluid – Formation. 15.B. Hyperaesthesia. cognition of depth. photoreceptors. Central analgesic pathway. Contents and functions of middle ear. Attention. & 5. hippopcampus. Light and Dark Adaptation. Color vision – role of retina. transduction of light signal. structure and function of cochlea – discrimination of pitch and loudness – Transduction of signal and excitation of auditory nerve. Intracranial tension. Light and Dark Adaptation. Epithalamus – Circadian rhythm. Weber-Fechner Law and Miller’s Law. Hemispheric specialization. Nice to Know : 1. 13. Conditioned reflexes. Auditory pathway – processing at various levels. Anaesthesia. functions. Functions. Accomodation to near vision. HEARING : 7. – Syllabus . Laminae of Rexed. Inner ear. Memory. 6. 5. Decorticate rigidity. Cerebellar function tests – signs of cerebellar disease. 4. 14. Cerebellum – morphology – deep nuclei and cortex – neuronal circuitry. SPECIAL SENSES Must Learn : VISION : 1.Physiology . functions. I M. perception of sound. 8. Spinal *. 14. Transduction and sensory pathway – central connections. Basal Ganglia – Connections. Aqueous humour and intraocular pressure. 3. connections. Sensing of head position and movement.48 9.B. Adaptation and potentiation. 10 Vestibular apparatus – Functional anatomy. Movements of the eyeballs. types. 4. Brodmann’s areas. Physiology of sleep and Arousal. 12. 12. 8. visual cortex. Apoplectic Stroke. 9. Limbic system – parts. Circulation. Functions. control. Metathalamus. External ear. control of the pupil and ciliary muscle. connections of cerebellum. 15. Disorders of attention and learning. 2. Senile dementia Learning in a case of split brain syndrome. VIII. Lachrymation. Effects of lesions in basal ganglia and related nuclei. Effects of lesions in amygdale. transduction of light signal. spinal shock. stereopsis. visual pathway. Reticular formation. Image forming mechanism of the eye. 13. Cause of headache. 10. 10. Types of tremor. Syndrome of Hemisection and Transection of the spinal cord. Propeties of synapses and reflexes. Effect of ions on neuronal excitability. cognition of light and colour. Aphasia and Amnesia. 11. 11. functions. Learning. mammilary bodies. Hypothalamus – Nuclei.

Colour weakness and colour blindness – types. 11. control of secretion – hierarchy. Islets of Langerhans. Wald’s visual cycle. General aspects of endocrine physiology. Histamine. 4. Parathyroid. 3. 10. response of target organ cells and regulation of secretion in respect of each of the following endocrine glands : a. Biosynthesis of protein and steroid hormones. Oculokinetic nystagmus. dysgeusia. Audiogram. Nice to Know : 1. Hormonal modulation of smell perception ( Exaltolide ). Lingual papillae and taste buds – stimuli – pathways of taste – perception of tastes. Efferent control of sense organ. Kidney. Amyblyopia. Parosmia. 8. Thyroid. feed forward and feed back regulation. c. k. 7. Epiphysis cerebri. nerves and bulb.49 SMELL TASTE: 11. h. 12. 3. 2. pathways to new and old areas of cerebral cortex. Heart.B. mode of action and local effects of the Kinins. Serotonin. Refractory defects and there correction. f . Retinal detachment. transport. transport. g. 12. Squint.S. stimuli for secretion. Neruohyophysis cerebri. Effect of lesions in visual pathway: Word blindness. Corneal and conjunctival reflexes. receptors. perception of smells. 6. Hypothalamus. Neuronal plasticity. caloric test. j. Adrenal cortex. Pathway for papillary light reflexes and accomadation. Cochlear microphonics. ENDOCRINE GLANDS Must Learn : 1. Diplopia. Anosmia. 5.Physiology . Ptosis. Polymorphism in taste perception ( PTC ). Gastrointestinal tract. d. Ageusia. Hormones secreted. 9. Layers of superior colliculus and lateral geniculate body. l. Xenopthalamia. modulation of taste (miraculin) IX. Odorants olfactory mucosa. Paracrine regulators : Production. Impedance matching. Vertigo after a spin. second messengers. Spherical and chromatic aberration. Types of deafness – Tests for hearing – interpretation. location of receptors. Eicosanoids. e. 2. i. Leukoma and cataract. Adenohypophysis cerebri. Adrenal medulla. I M. Histology and blood supply of the glands. b. dangers of glaucoma. Presbycusis.B. Difference between peripheral and central retina. Enophthalamos. – Syllabus .

Questions asked from the “NICE TO KNOW” category should not exceed 20% of the total marks in each paper. Interaction between hormones. 5. Male sterility. – Syllabus . 3. rate of daily secretion.S. Functions of placenta. REPRODUCTION Must Learn : 1. changes in ovary. Immunological test for pregnancy. Impotence. methods of contraception. 2. Benefits of breast feeding. 7. As far as possible contemporary methods must be used. N. 3. Chemistry of the autacoids. Blood counts should be preferably done on collected I M. 4. half life and catabolism of the hormones. : (1) SEQUENCE OF TEACHING SYSTEMS : It is recommended that the order given in the syllabus be followed. Puberty. Capacitation. Menstrual cycle. Animal experiments must be limited to demonstration on frog tissues only. conception. Determination of day of ovulation. fertilization.S course: Note: Methods of performing experiments may differ from institution to institution. 6. Male sexual act. Lactation amenorrhoea. Circadian rhythm. Male Sex organs. Anovulatory cycles. TEACHING HOURS - 480 HRS. vagina – role of hormones. Parturition : Initiation and stages of labour. Colostrum Vs Milk. 2.B. Hormones secreted by testes – their actions. 5. Premenstrual tension.B.50 Nice to Know : 1. Breast development and lactation – hormonal control. Quevedoces. XXX. XXY. control of secretion. 4. senescence. Pregnancy. Biosynthesis. Cryptorchidism. uterus. 6.B. cause of amenorrhoea. Fertilization. (2) QUESTION PAPERS : Examination questions should be asked mostly from the “MUST LEARN” category. Mode of activation and mode of action of second messengers.B. X. 7. Foetoplacental unit.B. Sexual differentiation of gonads and genitalia in utero. infertility. Oogenesis. Female sexual act. Nice to know : 1. Spermatogenesis. Secretion of sertoli cells. Hermaphroditism : OX. Practical Physiology for I M. Effects of hypo and hyper-secretion of each hormone – clinical syndromes. 3. Physiology of mother and foetus. Climacteric. Biosynthesis and catabolism of oestrogens and progesterone. XYY syndromes. Female sex organs. 2. growth and development of the individual after birth.Physiology . Semen. Biosynthesis and catabolism of androgens.

Percussion of lung fields. 4. examination of bone marrow smear. Demonstrate the effect of posture on the vital capacity. 6. NERVOUS SYSTEM: 1. Determination of Peak Expiratory Flow Rate. examination of blood smear. Electro Cardiography Lewi's Triple response Reactive hyperaemia following occlusion Demonstrating the effect of drug like adrenaline and histamine on the skin. Examination of the Respiratory system by auscultation. 2. 4. Recording of the chest movement of the subject and demonstration of the effects of voluntary breath-holding and voluntary hyperventilation. 3. 2. Respiratory system: 1. 7.S. fragility of RBC. Examination of peripheral pulses (arterial and venous) Auscultation of pericardial areas Trace the limits of cardiac dullness Location of apical impulse.Physiology . Demonstrate the effect of posture on blood pressure and heart rate. 8. – Syllabus . Cardiovascular system: 1.1. Demonstration only. 3. Demonstrate changes in tidal volume before and after exercise. Demonstrate the pupillary reflexes on the subject provided. Examination of Respiratory system by inspection and palpation. ABO system 5) Bleeding time (preferably by the method of Ivy) 6) Clotting time (preferably by the method of Lee and White) Note: The following experiments may be shown as demonstration only – specific gravity of blood. Demonstration only: Computerised spirometer/spirograph. 5. 6. 3. 2.B. Haematology Experiments: Major 1) Total Leucocyte count 2) Erythrocyte count 3) Differential Leucocyte count 4) Absolute Eosinophil count Minor 1) Estimation of haemoglobin : 2) Packed cell volume 3) Erythrocyte sedimentation rate 4) Blood grouping: Rh factor.B. 5. Reticulocyte count. platelet count. 4. I M. Demonstrate the effect of mild/severe exercise on blood pressure and heart rate. Effect of hyperpnoea on breath holding time.51 blood wherever possible since finger prick methods give high variability.

12. vibration and stereognosis of the subject provided.S. 11. Examine the cranial nerves 3. Calculations Graphs. Examine the sensation of pain and temperature/touch.12.2005 I M.4 and 6 7. Amphibian Experiments: Brief demonstration with nerve-muscle and heart preparations is recommended.52 2.B. 10. 4. EVALUATION: Three clinical experiments (minor changed to clinical) ------------------------------------------------------I. 6. 13. Central Nervous System and Special Senses. These should be based on : a) b) c) d) Clinical problems Physiological principles. 3. Blood and Lymph. Cardiovascular system. Assess the visual acuity and visual field of the subject. 9.A. Examine the motor system of any one upper limb/lower limb of the subject provided. 5. Excretion. Demonstrate the stretch reflexes. Digestion.B. Endocrine Glands and Reproduction. Photographs.Physiology . 8. ---- UNIVERSITY EXAMINATION PATTERN . MARKS ------------------------------------------------------Theory 40 Practical 30 * Record 10 ---Total = 80 Marks. Examine the 8th nerve in the subject provided. Do the cerebellar function tests. Charts: Each institution is encouraged to prepare fresh charts every year. Paper – II Respiration. Examine the first cranial nerve.PHYSIOLOGY THEORY : Two papers of 3 hours duration and 100 marks each Paper – I General physiology. – Syllabus . Examine the facial nerve in the subject. Demonstrate the superficial reflexes. Examine the cranial nerves 9 to 12 in the subject provided. Examine the trigeminal nerve in the subject provided. Diagrams. ---------------------------------------------------------------------------------------------------------------------* 30th SAB dated 28.

5.A.10 (Calculation or Comment) 40 Marks (10 per Examiner ) -------------80 MARKS 40 Marks -----------40 Marks ------------Practical – 2 ( 1 ½ hrs.Physiology .53 PATTERN OF QUESTION PAPER : ** Essay Questions Short Notes Short Answer Questions 2 x 15 Marks = 30 Marks 10 x 5 Marks = 50 Marks 10 x 2 Marks = 20 Marks ------------Total = 100 Marks ---------------------------. 35% in I.. Haematology ) …… Haematology : Major – 20 Minor 10 Chart on Paper – I portions .S.2008 I M.B. – Syllabus ... Chart on Paper – II portions (Calculation or Comment) --: 40 Marks 30 Marks ( 10x3 ) 10 Marks --------------40 Marks -------------- PRACTICAL EXAMINATION: A maximum of 25 candidates per day of practical examination is desirable.--------------- Oral PRACTICAL EXAMINATION Practical – 1 ( 1 ½ hrs. 50% in Theory including Viva …… 50% in Practical …………………. ………………………. MARKS QUALIFYING FOR A PASS : 50% in Theory ……………………. } --Cardiovascular & Nervous Systems... 100/200 120/240 40/80 28/80 ---------Grand Total = 200/400 -------------------------------------------------------------------------------------------------------------------------** MCQ’s withdrawn from August 2008 onwards – 35th SAB held on 20.B. Clinical Physiology ) Three minor experiment – } One each on Respiratory.

(12) suggest experiments to support theoretical concepts and clinical diagnosis. (7) describe mechanisms involved in maintenance body fluid and pH homeostasis.54 I M. (ii) OBJECTIVES: (A) KNOWLEDGE: At the end of the course. (2) delineate structure.S. (4) describe digestion and assimitation of nutrients and consequently or malnutrition consequences of malnutrition.B.B. (11)familiarize with the principles of various conventional and specialised laboratory investigations and instrumentation analysis and interpretation of a given data.B.Biochemistry . (i) GOAL: The broad goal of the teaching under-graduate students in bio-chemistry is to make them understand the scientific basis of the life processes at the molecular level and to orient them towards the application of the knowledge acquired in solving clinical problems. I M. BIOCHEMISTRY Biochemistry includes Medical Physics and Molecular Biology. (10) outline the biochemical basis of environmental health hazards.B. (9) summarize molecular concept of body defences and their application in medicine. (3) summarize the fundamental aspects of enzymology and clinical application wherein regulation of enzymatic activity is altered. – Syllabus . expression and regulation the principles of genetic engineering and their application in medicine. (5) integrate the various aspects of metabolism and their regulatory pathways. the student shall be able to: (1) describe the molecular and functional organisation of a cell and lies its subcellular components. (8) outline the molecular mechanisms of gene.S. function and inter-relationship of biomolecules and consequencies of deviation from normal. (6) explain the biochemical basis of inherited disorders with their associated sequelae. biochemical basis of cancer and carcinogenesis.

Lipoproteins I M. three dimensional structure of specific proteins with their structure and the suitability of their structure to their functions. Mitochondria. Glycoproteins. Endoplasmic reticulum. their properties. A brief account of the sub cellular fractionation and markers for each organelle and fraction. (3) demonstrate the skills of solving scientific and clinical problems and decision making. Insulin. Amino acids that are present in proteins. naturally occurring peptides. Fluid mosaic Model of membrane.55 (B) SKILLS: At the end of the course. Sucrose. Glycosamino glycans. cytosol. lysosomes. Phosholipids. the student shall be able to: (1) make use of conventional techniques/instruments to perform biochemical analysis relevant to clinical screening and diagnosis. Glycogen. membrane transport. Hemoglobin. Golgi apparatus. blood group antigens. peroxisomes. classification of aminoacids. Maltose. Plasma proteins and their functions.B.S. Structure of Proteins: General. Amino acids that are not present in proteins. unsaturated polyunsaturated acids. Pentoses. Peptide bond formation. Structure and functions of Carbohydrates: Glucose. Objective II Structure and function of biomolecules and the consequences of derivation from normal: Structure of amino acids. Chromatographic separation of mono and disaccharides. Cellulose. Electrophoresis of Serum proteins. Lactose. Starch. Fatty acids – Saturated. Interpretation of Serum Protein Electrophoresis patterns of – Cirrhosis liver. Structure and functions of Lipids. The structure and functions of Plasma membrane. Fructose. Lysyl oxidase – Lathyrism and role of copper. Membrane structure. cholesterol. Nephrotic syndrome. Organelles like Nucleus. Elastin. – Syllabus . (2) analyze and interpret investigative data. The composition of nucleosomes. Multiple Myeloma when compared to normal. Ascorbic acid deficiency – Collagen abnormalities. Ribosomes. Triacyl glycerol.Biochemistry . Galactose. Eicosanoids. gangliosides. Clinical: Muscle injury and myocardial infraction – Myoglobinuria Emphysema – the Collagen and elastin changes in the lungs. Collagen. (C) INTEGRATION: The knowledge acquired in biochemistry shall help the students to integrate molecular events with structure and function of the human body in health and disease. – Myoglobin. THEORY Objective I Describe the molecular and functional organisation of a cell: The structure of cell and intercellular components. Separation techniques – Electrophoresis and chromatography.B.

Clinical: Enzymes in clinical Diagnosis. Hyper and hypoparathyroidism. Gammacarboxy glutamate residues and its role in calcium binding.Biochemistry . Classification. Nucleosides. the respiratory chain and oxidative phosphorylation. Their recommended Dietary Allowance. Vitamin E – Source. absorption. structure. Its role in glutathione peroxidase. scurvy. Enzyme turnover (half life). night blindness. Hypervitaminosis A. Vitamin D – Active forms. Pantothenic acid. Their deficiency manifestations. specificity. Ascorbic acid: Source. Vitamin K – Source. RDA. RDA. Constitutive and inducible enzymes. Anti vitamins. Niacin. Role of skin. RNA. metabolism and coenzyme functions of Thiamine. Pyridoxine. Isozymes. Biotin. coenzyme functions. Deficiency manifestations. Vitamin A – The three forms of the vitamin. KM. Zymogen activation. Liposomes. Objective V and VI: Integrated Metabolism and inherited disorders. General properties – effect of temperature and pH. Riboflavin. The deficiency manifestations – rickets. absorption of sugars. Enzyme regulation: Allosteric. RDA and functions of E – Role of selenium and Vitamin E function. its role in the activity of enzyme in different tissues. Enzyme inhibitors. its role in collagen synthesis. its role in one carbon metabolism and purine synthesis megaloblastic anemia. Visual pigments. – Syllabus . the chemistry of vision and colour vision. Deficiency manifestations. hydroxylation reactions. Bioenergenetics. Biologic oxidation. the role of ATP. Rate limiting enzymes. antioxidant properties. Covalent modifications. Nucleotides. Objective IV: Vitamins: Water soluble – source. Hypervitaminosis D. Enzyme – Nomenclature.S. Structure and functions of Nucleic acids: Purines and pyrimidines. Objective III: Fundamental aspects of enzymology and clinical application. Digestion and absorption of carbohydrates. The role of calcitriol in calcium and phosphorous maintenance with the help of PTH. Fat soluble Vitamins: Beta carotene – its antioxident property. Storage and transport in plasma. cofactor. liver and kidney in the synthesis of calcitriol.B.56 Clinical: Surfactant. Active site. Intracellular location of enzymes. DNA. I M. Product inhibition. Vitamin K dependent proteins and coagulation factors. source. Digestive enzymes. feedback regulations. reducing properties. conversion of carotenes to Vitamin A absorption of Vitamin A.B. RDA. RDA. Histones – Their role in DNA arrangement in Chromosomes GENES. its role as a provitamin. Folic acid.

liver. brain. breakdown of hemoglobin. Hartup disease. Metabolism in specify tissues and organs RBC. muscle. abnormal hemoglobins. the ability of hemoglobin to accept the deliver oxygen. heart. Digestion of lipids.B. Hemoglobin. and hydrogen ion in the hemoglobin molecule. positive co-operativity. Fatty acid oxidation (beta. starvation ketosis.Biochemistry . Mechanism of amino acid absorption. pentose phosphate pathway. Forms of hemoglobins present in adults. methemoglobin. 3 bisphosphoglycerate. Clinical: Gout. lipid profile – values interpretation. The critic acid cycle – catabolism of acetyl CoA… Glycolysis. Clinical: Haptoglobins. jaundice. chemistry of respiration. Compounds derived from cholesterol. Galactosemias. binding of Oxygen. cholesterol synthesis. BUN. metabolism of glycogen. Acute pancreatitis.S. Phenyl Ketonuria. lipoproteins metabolism. Digestion of proteins. specialised compounds derived from aminoacids. metabolism of fructose and galactose. Sickle cell disease. I M. albinism. and its control. adipose tissue. starvation. Metabolic integration Fate of Glucose – 6 phosphate. Tri Glyceride Synthesis and storage. hyperlipidemias. Maintenance of Blood glucose.B. histidine. ketone bodies synthesis and breakdown. Carbon di oxide. plasma urea levels serum creatinine levels. formation of chylomicrons and lymphatic entry of lipid into circulation. maple syrup urine disease. absorption of fat soluble vitamins. alpha and omega) Metabolism of Propionyl CoA. fetal and embryonic hemoglobin’s. branched chain amino acids. Gluconeogenesis. Brief outline of purine synthesis and degradation. alkaptanuria. disposal of the amino nitrogen. Role of Bile salts and bile on lipid digestion and absorption. Calcium proteins. HGPRT deficiency. Bhor effect. Glucose Tolerance test. heme synthesis.57 Clinical: Lactose intolerance. Glycogen storage disorders. Osmotic diarrhoea. transmination and deamination reactions. Essential Fructosuria. Cholera. tryptophan. Their use in kidney function evaluation. Clinical: Hyperammonemias. Purine – brief outline of synthesis and degradation. Fructose Intolerance. Metabolism of eicosanoids. Role of 2. Metabolic adaptations in fed state. Clinical: Diabetic ketosis. thalessemias. methioine and transmethylation reactions. bilirubin metabolism. Control operating in all the metabolic pathways. Glycosuria. – Syllabus . porphyrias. Fatty acid Biosynthesis. catabolism of the carbon skeleton of tyrosine. Carbaminohemoglobin. homocystinuria. Acetyle CoA. Clinical: Diabetes Mellitus. phenyl alanine.

their major functions. Magnesium. Iron. Post translational modifications with examples. Operon hypothesis. Clinical: Protein calorie malnutrition. Recombinenet DNA technology and its application. Histone. energy derived from carbohydrates. gene therapy. processing and modification. mutations. electrolyte balance. alkalosis. I M. Obesity. repressors. binding of regulatory proteins to DNA. Mineral metabolism: Iodine. respiratory control. missence. Zinc.B. reverse transcription. nucleosomes. Nonsense mutation. SDA. Suppressor RNA molecules and their role on mutations. synthesis – hyper and hypo gammaglobulinemias. frame shift. Dietary fibres. Osmolality. transgenic animals. different types. Objective XI: Molecular concept of defence Immunoglobulins – structure.B. restriction fragment length polymorphism. monoclonal antibodies. Objective VIII: Nutrition: Major nutrients. replication and repair.58 Objective VII: Maintenance of body fluids and pH: Intracellular and extracellular electrolytes. chromosomes. Protein synthesis and the genetic code. Exons and introns. Their diagnosis. Regulation of GENE expression: Enhancers.S. maintenance of pH – the role of blood buffers. Immune deficiency. RNA – different RNA’s their synthesis. Mutations – point mutations. role of the kidney. – Syllabus . The compensatory mechanisms. protein malnutrition – kwashirokor and Marasmus. selenium and other trace minerals. Polymerase chain reaction. BMR. acidosis. prenatal diagnosis.Biochemistry . Objective IX: Hormones: Mechanism of hormone action. anion gap and blood gas measurements – their clinical use. copper. Their diagnosis and dietary correction. fats and proteins. Objective X: Molecular mechanisms of gene expression: DNA organisation. Antibiotics and their effect on translation. Ribozymes. maintenance of body water. blot techniques and their application.

Biochemistry . hydrolysis – followed by benedict’s and iodine tests. 6. acetone. Reactions of carbohydrates to identify – Mono. Spectroscopy and derivatives of Hemoglobin.S. bile salts. oncogenes. Reactions with proteins – Precipitation with half and full saturation salt solutions. Bial’s. Anticancer agents. kidney function tests. environmental pollutants.59 Objective XII: Environmental health hazards. bile pigments. 3. Quantitative experiments Estimation of: Plasma glucose Plasma urea Serum total proteins Serum creatinine Urine creatinine Serum Uric Acid Serum Phosphorous Serum Alkaline phosphatase Teaching Hours – 240 Hrs.B. di and polysaccharides. reducing sugar. Lactose. colour reactions for amino acids – albumin. Abnormal constituents of urine. Carcinogens. – Syllabus . casein. mutagenesis. Objective XIII: Specialised laboratory investigations: Liver function tests. Xenobiotics – Detoxification. Seliwanoff’s. PRACTICAL SYLLABUS Exercise: 1. I M. 2. blood. Heat coagulation test. Phosphorus. Constituents of normal urine. DNA repair. Benedict’s.B. Cell cycle control. protein. 4. biochemistry of cancer and carcinogenesis: Occupational hazards. 5. tumor markers. Tests – Molisch. Milk analysis to record calcium. Foulger’s. Benedict’s Barfoeds. Starch – Iodine test.

3.B. 8. Plasma Urea and Urine Albumin and Blood Liver Function Tests : Serum Bilirubin. Identification of – Hemin crystals. Ascorbic acid. multiple myeloma. Maltose. Serum Total Proteins Pancreatic Function Tests: Plasma glucose. Urine glucose (Serum amylase values given by the skilled assistant for interpretation) Galactosemia Essential Fructosuria Nutrition SPOTTERS 1. Oxy. 5. 10. Egg and Milk: The biological values for the proteins present in these. : To identify the essential amino acids in proteins. Urine Bile salts and pigments. Electrophoretic patterns – Normal serum proteins. 7. : CSF – Glucose and Proteins. 4. Iron. Nephrotic syndrome. Folic acid. : Serum Total proteins. : Galactose in Urine.60 Fluid proteins estimation Clinical Exercise: Diabetes Mellitus : Plasma Glucose. Urine Glucose and acetone. Multiple myeloma.S.Biochemistry . cirrhosis liver. Identification of Hemoglobin Derivatives using Spectroscope. : Serum and 24-hours urine phosphorous. pH meter. fructose. (Serum proteins) Cirrhosis liver. reduced and Methemoglobin.B. Nephrotic syndrome. Colorimeter. Nutrition: Identify source for Beta carotene. Centrifuge. I M. GTT – Plasma Glucose and Urine Glucose. Serum protein electrophoresis pattern. 24 – hour urine proteins. Osazones of glucose. Normal. 9. Chromatogram of Phenyl Ketonuria. CSF analysis Nephrotic Syndrome Renal Functions tests 2. – Syllabus . 6. Urinometer. 11. Lactose. : Creatinine clearance – Serum and 24 – hour urine creatinine estimation.

Alkalosis – Metabolic and Respiratory.B. Digestion and absorption of carbohydrates. Porphyrins. Metabolism of lipids and disorders of lipid metabolism. Electron transport chain and Biological oxidation. Charts: Acidosis – Metabolic and Respiratory. after 6 hour. 5.CHEMISTRY THEORY: TWO Papers of 3 hours duration and 100 marks each. Digestion and absorption of lipids. Chemistry.61 12.S. 4. 9. hemoglobin and metabolism of Bilirubin. Metabolism of Carbohydrates and disorders of carbohydrate metabolism. Heme synthesis. Molecular and functional organisation of the cell and its subcelular components. one week. Chemistry. Myocardial infraction – The enzyme levels immediately after the onset of Pain. 24 hours. 7. Citric acid Cycle and Metabolic integration. Nutrition.Biochemistry . Enzymes. 8.B. 3. – Syllabus . 6. Vitamins. I M. Lactate Dehydrogenase Isoenzymes (Electrophoretic pattern) Multiple Myeloma (with Electrohoretic pattern) Cirrhosis liver (with Electrophoretic pattern) Nephrotic syndrome (with Electrophoretic pattern) EVALUATION Internal Assessment : Theory : Practical : Record : 40 marks 30 marks 10 marks ----------Total : 80 marks ----------- UNIVERSITY EXAMINATION PATTERN – BIO . PAPER -I 1. 2.

Hyperuricemias. Practical exercise – II Major experiment with case discussion 40 marks 80 MARKS Minor experiment 20 marks 10 marks 10 marks ------------80 Marks -------------- Spotters………………………………………………………………… Charts Total PRACTICAL EXAMINATION: A maximum of 25 candidates per day of practical examination is desirable. absorption and metabolism of proteins. 8.62 PAPER . 5.B.S. Maintenance of Fluid and Electrolytes. Hormones.Biochemistry . inborn errors in Protein metabolism. Xenobiotics and cancer chemistry.II 1. Maintenance of pH and acid base disorders. 40 Marks PRACTICALS: Practical exercise – I 90 minutes. metabolism of Purines.5. 2. Digestion. Chemistry of purines. 4. Chemistry. Laboratory instrumentation. PATTERN OF QUESTION PAPER : ** Essay Questions Short Notes Short Answer Questions 2 x 15 Marks = 30 Marks 10 x 5 Marks = 50 Marks 10 x 2 Marks = 20 Marks ------------Total = 100 Marks -------------- ORAL………………………………………………………………………………. investigation and interpretation.2008 I M. 3. 6. ----------------------------------------------------------------------------------------------------------------** MCQ’s withdrawn from August 2008 onwards – 35th SAB held on 20. Molecular Biology. 9. 7.B. – Syllabus . Minerals.

S.Biochemistry . – Syllabus .A.B.B. Grand Total = = = = : 100/200 120/240 40/80 28//80 --------200/400 ------------ -------------------------------------------------------------------------------------------------------------------------------- I M.63 MARKS QUALIFYING FOR A PASS 50% in Theory 50% in Theory including Viva 50% in Practical 35% in I.

Seminar on the above topic.B. 8. (Principles of Sociology including demographic population dynamics). Introduction to health delivery system in rural and urban area in India. Natural history of disease and concept of prevention. National demographic goal. 14. (Dynamics of community behaviour). Introduction to Community Medicine. Social factors and morbidity pattern in rural area and urban area. Seminar on above topics. 11. 9. Seminar on above topic.B. 3. 13. 2. Seminar on above topics.64 I M.B. – Syllabus – Community Medicine . 60 Hrs. social factors related to health. Concept of Health and disease. Seminar on the above topics.S. 12. Concept of primary health care – compounds of primary health care – Health for all. 4. 7. 10. Mode of transmission of disease and dynamics of diseases. disease & disability in context of urban and rural area. LIST OF TOPICS 1. Behavioural Science and Psychology I M. COMMUNITY MEDICINE It would be desirable to ensure that teaching of Community Medicine is community oriented and community based learning experience will be more rewarding if problem solving opportunities are incorporated and teaching is carried out in an integrated fashion. 5.B. 6.S. Demography and demographic level in India and other countries. 15.

Water & Food analysis Laboratory 10. – Syllabus – Community Medicine .M. Two continuous Hours of classes per week (11. Milk Diary 13./M.) Forenoon should be organized once in a month from September to January..) on any day of the week for 15 weeks (2 Hours x 15 weeks = 30 Hours as per recommendation of Medical Council of India) should be conducted upto the end of November.B. Institute/Department of Mental Health 11. to 1.M. Seminars. Nutrition Rehabilitation Centre Suggtested Time-Table As per Medical Council of India (i) Theory. **** I M. Water works .S. Practicals (ii) Visits to Institutions of Health .00 P. Institute of Rehabilitation 12. Also 5 field visits of 6 Hours duration (7.65 I &II Semester – List of visits to Institutions 1-3 Primary Health Centres – 3 centres 4-6 Urban Health Posts 7.00 A.00 A.30 Hours . to 1.00 P.3 centres 8.30 Hours (Field Visit) Adapted Time /Table Starting from August.B. Sewage farming 9.M.

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