Cloxacillin Brand Name: Cloxapen, Tegopen Classification:anti-infective Dose: 500 mg 1 cup q 6 hours P.

O Mechanism of action: inhibits cell wall synthesis and causes call lysis or death in bacteria that make rigid,cross-linked call wall in several steps. Indications: to treat mild respiratory track infections or localized skin and softtissue infection cause by penicillinase-producing staphylococci. Contraindications: Hypersensitivity to penicillins. Adverse effects: Cloxacillin may cause stomach upset, diarrhea, nausea, and vomiting during the first few days as your body adjusts to the medication. If these symptoms persist or become severe, inform your doctor. An allergic reaction may occur while taking Cloxacillin. Symptoms include: - Skin rash; - Itching; - Hives; - Difficulty breathing; Common side effects are: - Diarrhea Less Severe; - Feel Like Throwing Up Less Severe;; - Head Pain Less Severe; - Throwing Up Less Severe Nursing responsibilities: • Determine previous exposure and sensitivity to penicillins and cephalosporins and other allergic reactions of any kind before treatment is initiated. • Monitor for S&S of anaphylactoid reaction (see Appendix G) or other signs or symptoms of hypersensitivity reaction (see Appendix F) as with other penicillins. • Take medication around the clock, do not miss a dose, and continue taking the medication until it is finished. • Report to physician the onset of hypersensitivity reaction and superinfections. • Check with physician if GI adverse effects (nausea, vomiting, diarrhea) appear. • Instruct patient to take the drug with one full glass of water.

Penicillin G Brand Name: Pen G Dose: Pen G NA 4 m units q 8 hours ANSTC(+) Mechanism of action: Inhibits enzymes responsible for cell wall synthesis of susceptible organisms, this creates an osmotically unstable cell wall that swells and bursts from osmotic pressure.

Contraindications: Patients with known allergies to penicillin. hemolytic anemias of an immunologic type. platelet dysfunction. salmonella typhosa and other salmonella. They can disrupt the normal gastrointestinal flora and cause nausea. Contraindication: Hypersensitivity to penicillin Adverese effects: hypersensitivity. • Check with physician if GI adverse effects (nausea. At high doses penicillin can have a toxic effect that can cause seizures. Precaution with pregnancy category B.Indications: Penicillin G is reserved for severe infections. and hypersensitivity to cephalosporins. e. abdominal pain. which is approximately 3% of the population. A different formulation should be used in these patients such as penicillin procaine that allows a slow release into the serum from the intramuscular site. destroyed by penicillinase Indications: Respiratory track infection due to non-penicillinase-producing staphylococci. broad-spectrum antiobiotic suitable for gram-negative bacteria. Adverse effect: The penicillins are among the least toxic drugs known. • Report to physician the onset of hypersensitivity reaction and superinfections. They rarely elicit adverse reactions in humans unless present in excessive concentrations. P. or when the oral route is compromised (as in malabsorption syndrome and vomiting). do not miss a dose. vomiting. and nephritis. • Note history of sensitivity to the drug . including streptococcus pneumonia.infective Dose: Mechanism of action: synthetic. and continue taking the medication until it is finished. and streptococci. dosages should be decreased since excretion of drug is by the renal system. colitis. In patients with renal impairment.GI infections due to shigella. gastritis. lactation. • Take medication around the clock. • Monitor for S&S of anaphylactoid reaction (see Appendix G) or other signs or symptoms of hypersensitivity reaction (see Appendix F) as with other penicillins. Acid resistance. and anorexia. diarrhea. encephalitis.marabilis and entorococci. vomiting. diarrhea) appear Ampicillin Brand name: Ampicillin sodium Classification:anti. Nursing Responsibilities: • Determine previous exposure and sensitivity to penicillins and cephalosporins and other allergic reactions of any kind before treatment is initiated.coli. nausea and Vomiting. and for some patients requiring prophylactic coverage. stomatitis Nurisng responsibilities • List characteristics of signs and symptoms.

7. 5. Don’t give large doses of vitamin B 12 routinely. 6. transitory exanthema. folate levels before beginning therapy. and nucleoprotein and myelin synthesis. Protect Vit. administration bec. Don’t refrigerate or freeze. Indications: Treatment and prevention of vitamin B12 deficiency. Obtain a sensitivity test history before administration 3. Don’t mix parenteral preparation in same syringe with other drugs.V. Neuropathies caused by disease states Contraindication: Hypersensitivity to Vit B12 Adverse effect: CV: peripheral vascular thrombosis. hematopoiesis. . Nursing responsibilities: 1. Vit. Avoid I. determine reticulocyte count. faster systemic elimination will reduce effectiveness of vitamin. Skin: itching. Monitor patient for for adverse effects. GI: transient diarrhea. Respi: pulmonary edema. Nutritional support in painful neurological manifestations of neuritis & neuropathy eg cervical & shoulderarm syndrome. drug is lost through excretion. and diseases caused by low vitamin B12 levels. B 12 from light. food mat interfere with absorption • Instruct the patient not to save pills for future use with family members/friends who have similar condition • Take for prescribed number of days even if symptoms subside. ischialgia & sciatica. 2. 4. Vitamin B Brand name: vitamin B Polynerv Classification: Vitamins and Minerals(Vitamin B1 in combination with vitamin B6 and/or vitamin B12) Mechanism of action: A coenzyme that stimulate metabolic function and is needed for cell replication. heart failure. lumbago. iron.• Take 1 hour before or 2 hours after meals. hct. urticaria. B 12.

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