Nama Obat Gentamicin 0,1% zalf kulit Oxytetracycline 0,1% zalf kulit Mikonazole Hydrocortisone 2,5%

Indikasi Infeksi bakteri Dermatitis dgn infeksi Infeksi jamur Dermatosis responsif KS

Kontra Indikasi Hipersensitivitas Hipersensitivitas Hipersensitivitas Infeksi virus/jamur, lesi tuberkular/sifilis, infeksi bakteri Hipersensitivitas, infeksi jamur Hipersensitivitas Hipersensitivitas Hipersensitivitas

Efek Samping 3-4 x/hari 4 x/hari Iritasi, dermatitis kontak Atrofi kulit, iritasi, folikulitis, hipertrikosis Atrofi kulit, iritasi, folikulitis, hipertrikosis Rash, demam, angioedema Ototoksik Menghancurkan kontrasepsi latex Edema perifer, hipotensi, palpitasi, takikardia, flushing, pusing, nyeri kepala, nausea, miksi lbh sering, myalgia, tremor, ggn hepar Hipotensi, takikardia, nyeri dada, palpitasi, pruritus, hiperkalemia, angioedema, skin rash, batuk nonproduktif, pusing, ggn pengecapan, proteinuria

Dosis

2 x/hari Sesuai petunjuk dokter

Betamethasone Zalf kulit 2-4 Chloramphenicol 1% zalf mata Chloramphenicol 3% tetes telinga Nistatin vaginal

Dermatosis responsif KS Skabies, pedikulosis Infeksi okular Otitis eksterna Kandidiasis vaginal

Sesuai petunjuk dokter

1-2 tetes tiap 2 jam 2-3 tetes; 2-3 x /hari 100.000-200.000 U/hari, 14 hari 2x1 10-40 mg/hari

Nifedipin 10 mg (Ca antagonis)

Hipertensi, angina pectoris

Captopril 12,5 & 25 mg (ACE inhibitor)

Hipertensi, gagal jantung, post MI (3 hari stlh), neuropati diabetik

MI akut, shock kardiogenik, acute unstable angina,serangan angina pada chronic stable angina Hipersensitivitas, hamil, ggn ginjal, angioedema herediter

HTN Initial : 12,5 mg, 2x1 Maintenance : 25-50 mg, 2x1 HF I : 6,25-12,5 mg, 2-3x1 MI : 6,25 mg/hari ND : 25 mg, 3x1 (1 jam AC atau 2 jam PC) 1x1

Aspilet (antikoagulan, antikoagulan&fibrinolitik, analgetik&antipiretik) Ibuprofen 400 mg (NSAID, obat KV gol lain)

Angina pectoris & MI

Kelainan darah, asma, ulkus peptikum aktif

Nyeri & inflamasi, demam

Ulkus peptikum aktif, hipersensitivitas

Ulkus peptikum, ggn GIT, waktu perdarahan meningkat, tinnitus, pusing, hipotrombinemia Dyspepsia, muntah, nyeri perut, heartburn, nausea, diare, nyeri epigastrium, edema, retensi cairan, pusing, rash, tinitus

2x½ Nyeri & inflamasi 1,2-1,8 g/hari, maintenance 0,6 -1,2g/hari Demam 200-400mg setiap 4-6 jam 2x1 N&I : 75-150 mg/hari M :Initial 50 mg (serangan pertama), ulang 2 jam kmdn jk perlu, dan lalu setiap 4-6 jam 3x1 Alergi Initial : 30 mg hari pertama Turunkan 5 mg per hari hingga 21 tablet habis RA : ≤ 10 mg/hari Asma akut

Diclofenac sodium (NSAID)

Nyeri & inflamasi, migrain

Ulkus peptikum aktif, hipersensitivitas thdp NSAID, trimester 3 kehamilan, terapi nyeri postoperative CABG

Ggn GIT, pusing, nyeri kepala, rash, pdarahan GIT, ulkus peptikum, ggn ginjal, SJS, TEN

Prednisone 5 mg

Alergi, RA, asma akut, TBC berat, TB ekstraparu, kusta

Hipersensitivitas, varicella, infeksi jamur sistemik, infeksi bakteri berat

Insomnia, nafsu makan meningkat, pusing, nyeri kepala, hirsutisme, hipopigmentasi, DM, intoleransi glukosa, hiperglikemia, athralgia, katarak, glaukoma, epistaksis, diaphoresis, sindrom Cushing, edema, hipertensi, muscle wasting,

aritmia. alopesia. anemia aplastik. lansia) Penyakit rematik. neuropati perifer. nefropati akut. kompresi tali pusat. infeksi atau trauma berat Asidosis metabolik akut dgn atau tnp koma. tapering off selama 4-8 mggu 2-4 mg (hingga 8 mg). selama 1-2 mggu Initial : 100 mg/hari. 1-2x/hari Gout 40 mg/hari selama 5-7 hari Muskuloskeletal Initial : 40 mg/hari. kehamilan Tremor. pingsan Dewasa 0. laktasi Allopurinol 100 mg Gout. palpitasi. alergi Anoreksia. frekuensi miksi meningkat Gangguan GIT. muntah. kehamilan. agranulositosis. nyeri kepala. dosis tunggal Maintenance : 10-30 mg/hari.osteoporosis. gagal hati atau ginjal berat. kram otot. perdarahan GIT. hipotensi. diabetic ketoasidosis. lemas. muntah. nausea. selama 2 hari Maintenance : 20 mg/hari. trimester 3 kehamilan. maks 800 mg/hari Piroxicam (NSAID) Hipersensitivitas. penyakit muskuloskeletal akut Hiperkalsemia dan hiperkalsiuria 2x1 <50 thn : 1000 mg Ca/hari >50 thn : 1200 mg Ca/hari 2x1 Rematik Initial : 20 mg/hr. angioedema. anemia hemolitik. lalu naikkan hingga 15 mg/hari. vertigo. nyeri abdominal. herpes zoster Hipersensitivitas Nausea. penyakit jantung Penyakit hepar berat. gangguan GIT. TEN Kalk (calcium lactate) Suplemen nutrisi (pertumbuhan. dyscrasia. flatulens. gangguan hepar. kejang 40-60 mg/hari selama 3-10 hari TB : 40-60 mg/hari. peningkatan enzim hepar Nausea. serangan gout akut Samclamide 5 gr (Glibenclamide) DM tipe 2 Metformin 500 mg DM tipe 2. atralgia. 3-4x/hari Salbutamol 2 mg PO : bronkospasme akut Griseofulvin 125 mg Dermatofitosis Eklampsia dan preeclampsia berat. maks 20 mg/hari 1x1 DM 500 mg/hari. demam. Lyell’s syndrome (urtikaria. nyeri kepala. ggn renal. cholestatic jaundice. 2-3 x/hari Maks 2. threatened miscarriage. IUFD. fotosensitivitas. anemia aplastik Hipoglikemia. nyeri kepala. tinnitus. muntah. menyusui.25 g/hari . ulkus peptikum aktif. DM tipe 1. malabsoprsi vit B12. infeksi intrauterine. takikardia. ibu hamil. pusing. mulut kering. hipertensi. ggn jantung. hipoglikemia. rash. rash. pruritus. diare. rasa tdk nyaman pada dada dan Initial : 2. nyeri kepala. haus meningkat. metallic taste. ggn tiroid. DM tipe 1. gangguan GIT. SJS. penglihatan kabur. PP. diare. hiperuricemia Hipersensitivitas. urtikaria. atralgia). ulkus peptikum. nausea. gout akut. 1-2x/hari Rambut & kulit 2-8 mgg Kuku jari tangan 6 bln Kuku jari kaki 12 bln Anak : 10 mg/kgBB/hari 3 x 1 atau 3 x 1/2 Aciclovir 400 mg Herpes simpleks. rash. konstipasi. diare. trombositopenia. limfadenopati. muntah. laktasi Rash.5-5 mg/hari. bronkospasme paradoksikal. gangguan pengecapan.5-1 g/hari. bradikardia. hemoraggia antepartum. parestesia. varicella zoster. SLE. penurunan BB. SJS. alkoholism. PCOS Hiperglikemia berat.

3. palpitasi. meningkatkan imunitas.7. glaucoma and subcapsular cataracts. 3x/hari Epilepsi Drowsiness. ggn pencernaan Batuk berdahak Hipersensitivitas >2000 mg/hari : Stomach upset. tremor. nervous. MAOI. edema angioneurotik.5-1.perut. atau 3 x 1 GG (Guaifenesin) DMP Dextromethorphan Tablet dan sirup OBH syr Batuk tidak berdahak Risiko mengalami gagal napas. urtikaria. mengatasi stres Defisiensi vit B6. antioksidan Defisiensi vit B1. 3 x ½ . diare 3x1 Gangguan neurologis. fungal disease of the eye.12 Stress.2. Increased susceptibility to infection. atau 3 x 1 3x1 3 x ¼ . palpitasi. increased appetite. ophthalmic use in viral. systemic absorption 3 x ½ atau 3 x 1 Adult: 0. meningkatkan energi. . gangguan pencernaan. neuritis perifer pada kehamilan. pusing. 500 mg/hari. slm 1 mggu. motion sickness. nyeri kepala. Growth retardation.6. up to 300 micrograms/kg daily may be used in emergency situations. ggn GIT 3 x ½ atau 3 x 1 Hypersensitivity. numbness 3 x ¼ . flushing. gangguan neurologis Defisiensi vit B12 (numbness atau tingling pada tangan dan kaki. Child: 1 mth–18 yr: 10–100 mcg/kg daily in 1–2 divided doses via oral admin. 3 x ½ .75-9 mg daily in 24 divided doses. depresi. katarak. menggigil. diare. folliculitis. adjusted according to response.7 g/hari. peptic ulcer. muntah. local irritation. kalkulus urinarius Pusing. Topical application: Dermal atrophy. nyeri kepala. delayed wound healing. anemia. asidosis laktat pada alkoholism dan gagal ginjal PCOS 500 mg/hari pagi slm 1 mggu.9. pusing. 2x/hari. serum sickness Inflamasi Dewasa : 15 ml. menurunkan asam urat. pertumbuhan dan perbaikan jaringan. Cushing-like features. SSP ggn keseimbangan) B1. mulut kering. may also be given via IM/IV admin. batuk persisten atau kronis GI discomfort. increased fragility of the skin. nausea. colitis ulserativa. letargi. gangguan GIT 3 x ½ atau 3 x 1 (200-400 mg setiap 4 jam) 3 x ½ atau 3 x 1 (10-20 mg setiap 4 jam) CTM Chlorpheniramine maleat (antihistamin dan antialergi) Dexametason Terapi suportif untuk batuk berdahak dan tidak berdahak Terapi simptomatis untuk alergi seperti bersin. GI upsets. pancreatic dysfunction and pancreatitis. 1. nyeri. vertebral compression fractures.5. anemia defisiensi Fe. osteoporosis. napsu makan menurun. fatigue. active untreated infections. serangan akut. 2-3x/hari 3x1 Vit C Vit B1 Vit B6 Vit B12 Vit B complex Prevensi dan terapi defisiensi vit C. rash. nausea. glaucoma. fatigue. 3x/hari Anak : 5 ml. drowsiness. dermatitis.

depression. blood disorders (e. nausea. blood dyscrasias (e. demam. Potentially Fatal: Very rare. impotence. diarrhoea. agranulositosis. agranulocytosis. sore throat. epigastric burning. digunakan bersamaan dgn chlorpromazine Perdarahan GIT. hallucinations. mechanical obstruction and perforation. maks 15/hari Anak : 1 ½ tab. oral candidiasis. candidiasis of mouth and throat. alergi. diarrhoea. confusion. Max: 12 mg/kg/day.g. nausea. galactorrhoea or related disorders. restlessness. Inhalation: Hoarseness. rash). phaeochromocytoma. thrombocytopenia. . rematik Bleeding disorder. somnolence. transient increase in plasma aldosterone levels. children. dyspepsia Porphyria. Extrapyramidal symptoms. headache.and toxicity with occlusive dressing on application to large areas of the body and broken skin. obstruksi intestinal Amoxicillin 500 mg Amoxicillin syr 125 mg/5ml Cotrimoxazole 480 mg Tetracycline 250 Infeksi bakteri Gram + dan Infeksi bakteri Gram + dan Infeksi bakteri. liver damage. Repeat dose 3 times at 2-hrly intervals. Oesophageal ulceration. given 1 hr before start of treatment. Topical application to eye: Corneal ulcers. allergic reactions. renal impairment. anaphylaxis. 1 .g. gynaecomastia. Gastro-oesophageal reflux disease Adult: 10-15 mg up to 4 times/day. skin rashes. maks 7½/hari Diaform (Kaolin & pectin) Diare Hipersensitivitas. Nausea and vomiting Adult: 2 mg/kg/dose. GERD. history of seizures. Headache. pregnancy. Antalgin 500 mg (NSAID) Metamizole Na atau Methampyrone PCT (analgesik non opioidantipiretik) Tab 500 mg &syr 120 mg/5ml Nyeri. acute renal tubular necrosis. bronchospasm. given 30 minutes before meals and at bedtime Konsumsi setiap habis BAB Dewasa : 2 ½ tab. drowsiness. hypertension. 3 x ½ atau 3 x 1 2x1 Metoclopramide GI haemorrhage. vertigo. vomiting. methaemoglobinaemia). dizziness. hypersensitivity reactions (e. lactation. anxiety. acne Hipersensitivitas Hipersensitivitas Diare. hypersensitivity reactions. hypotension. muntah Diare.6 thn : 3 x ¼ 6 – 12 thn : 3 x ½ Dewasa : 3x 1 3 x ½ atau 3 x 1 1-3 mo: 30 mg (3x1) 3 mo-1 yr: 60-120 mg (3x1) 1-5 yr: 120-250 mg (3x1) 6-12 yr: 250-500 mg (3x1) Mild to moderate pain and fever Antasida Ranitidine 150 mg (antagonis reseptor H2) Asam lambung berlebih Benign gastric and duodenal ulceration.g. leukopenia Nausea. May repeat 2 additional doses at 3-hrly intervals if needed. agranulocytosis). neutropenia. glaucoma and reduced visual ability. hypersensitivity. black hairy tongue. muntah 3 x ½ atau 3 x 1 3 x/hari (20 mg/kgBB) 2 x 1 atau 2 x 2 3 x 1 atau 3 x 2 Hypersensitivity. nausea. leucopenia.

hypersensitivity reactions. or 800 mg in the morning and 1. oncholysis. oliguria. Child: 1-3 yr: 50 mg tid. vaginitis. ataxia. Phototoxicity. confusion. Chloramphenicol 250 mg Ciprofloxacin 500 mg Infeksi bakteri Susceptible infections. changes in mood or mental state. diarrhoea. Lower respiratory tract infections. tinnitus. discolouration of tooth (children with developing teeth) and nails. Alternatively. rashes. azotaemia. tinnitus. insomnia. visual disturbances. Skin infections Infected animal bites. nephrotoxicity. LFT abnormalities. 15 mg/kg daily in divided doses for . hypersensitivity. or 0.pancreatitis. 3-7 yr: 100 mg bid. Transient increases in serum creatinine. Urinary tract infections. leukopenia. 7-10 yr: 100 mg tid. Avoid exposure to strong sunlight or sun lamps during treatment. unpleasant metallic taste. headache. and stomatitis due to overgrowth of Candida. All doses to be taken for 7 days. vomiting.2 g in the evening for 2 days. Transient leucopenia and 3 x 1 atau 3 x 2 (50mg/kgBB/hari) Dewasa : 2 x 1 Anak : 5-15 mg/kg bid Lincomycin 500 mg Severe anaerobic infections Hypersensitivity to lincomycin or clindamycin. dizziness. Furred tongue. laktasi Hypersensitivity. There should be an interval of 4-6 wk if treatment needs to be repeated. cardiopulmonary arrest Hypotension (IV). dermatitis.g. photosensitivity. nausea. hepatic and renal disturbances. drowsiness. convulsions. pseudomembranous colitis and tachycardia. Weakness. glossitis. headache. antibiotic-associated colitis. Not to be used concurrently with tizanidine. Gastroenteritis Hipersensitivitas. Potentially Fatal: Anaphylactoid reaction. vomiting. diarrhoea or constipation. neutropenia.Anaphylaxis GI disturbances e. 3x1 Adult: 500 mg 3 or 4 times daily. urticaria. pruritus ani. epileptiform seizures (high doses or prolonged treatment). blood dyscrasias. aplastic anaemia. tremor. nausea. Metronidazole 100 mg History of hypersensitivity to metronidazole or other nitroimidazole derivatives. Trichomoniasis Adult: 2 g as a single dose. proteinuria. jaundice. Haematological. Bone and joint infections. Vasculitis. Pregnancy (1st trimester) and lactation. hamil. Potentially Fatal: Anaphylaxis. rash. vertigo. Typhoid and paratyphoid fever. superinfections. joint pain. Numbness or tingling in the extremities. stomatitis. pancytopenia. glossitis. colitis. Child: ≥1 mth: 30-60 mg/kg daily in divided doses. thrombocytopenic purpura. Rarely. erythema multiforme. Gangguan GIT GI disturbances. hepatotoxicity.6-1 g daily in 2-3 divided doses for 7 days. agranulocytosis. phototoxicity.

fibrotic thickening of the heart valves. or 400-500 mg bid for 5-7 days. Bacterial vaginosis Adult: 2 g as a single dose. Raised liver enzyme values. blurred vision. dizziness. or 500 mg bid for 7-10 days. angina. Dysaesthesia. hypotension. constipation. To be taken as soon as possible at the 1st warning of a migraine attack. Ergotamine caffeine(1-50 mg) Acute migraine attacks. 6 tablets per wk and 2 courses of treatment per mth. 15 mg/kg daily in divided doses. Child: ≥2 yr: 400 mg as a single dose. Anaphylaxis. Vitamin K deficiency due to drugs or malabsorption Adult: 10-40 mg daily. Phytomenadione 10 mg (vit K) Hipersensitivitas Hydrochlorotiazide 25 mg (Diuretik) Severe hepatic and renal impairment. raised liver enzymes. headache. urinary retention. dyspnoea. dizziness. precordial pain. alopecia and dry mouth. GI discomfort. GI symptoms such as nausea. psychomotor impairment. Urethral discomfort and darkening of urine. extrapyramidal effects. allergic reactions. vomiting. 1 tablet. Hypersensitivity. Cerebral ischaemia and thrombosis. abdominal cramps. Neonates. 3-7 yr: /3 adult dose. SGOT elevations. sleep disturbances. jaundice. headache. headache. Anxiety. Acute migraine attacks Adult: Each tablet contains ergotamine tartrate 2 mg. hallucinations. paraesthesia. Child: 10 mg/kg as a single dose. cyclizine hydrochloride 50 mg and caffeine hydrate 100 mg. peripheral ischaemia.5 mg . diaphoresis. tenesmus. Increased BP. allergic reactions after SC and IM inj. cholestatic hepatitis. renal or hepatic impairment. Ascariasis. Not to be used when there is sepsis. coronary infarction. 7-10 yr: ½ adult dose. palpitations. Initially. Single or mixed infections due to susceptible worms Adult: 10 mg/kg as a single dose. hypotension (rare).thrombocytopenia. Child: 1-3 yr: ¼ adult 1 dose. tremor. Albendazole 400 mg Enterobiasis. nausea. Preexisting vascular disease including coronary disease. Max: 3 tablets in 24 hr. nausea. rash. liver impairment. rapid and weak pulse. formication. Giardiasis Adult: 2 g once daily for 3 consecutive days. Hypersensitivity reactions. Hookworm infections Pregnancy and lactation. Anaphylaxis. claudication. pain. muscle cramps and joint pains. Pyrantel 125 mg Anorexia. or 400 mg tid for 5 days. depression. 4 tablets per attack. Alternatively. arrhythmias. Pregnancy and lactation. vomiting. obliterative vascular disease. 7 days. Hyperthyroidism. 1-2 yr: 200 mg as a single dose for enterobiasis. Raynaud's syndrome and hypertension. confusion. if needed. additional doses of ½-1 tablet may be taken at halfhrly intervals. insomnia. swelling. Addison's Hypertension Adult: Initially. 12. Ensure an interval of at least 4 days between successive treatment courses. Potentially Fatal: Bone marrow depression. convulsions. diarrhoea. pruritus. phloebitis at the Inj site. cyanosis. abdominal pain. drowsiness. Volume depletion and electrolyte imbalance. dizziness. dry Adult: 400 mg as a single dose.

myasthenia gravis. pandangan kabur. Parkinson. nyeri kepala. 2-3 x/hari Anak : 2. feokromositoma HTN Hingga 500 mcg/hari slm 2 mggu. embolisme perifer & mesentrium . ggn hepar berat. may reduce to 25-50 mg daily or intermittently. sialadenitis.25 mg (anti-adrenergik) Hipertensi. Usual dose: 25-50 mg daily. depresi. lalu turunkan hingga dosis terendah Maintenance 100-250 mcg/hari Psikosis Hingga 1 mg/hari Dewasa : 1-2 tab. 1-5 yr: 2. midriasis. muscle pain and cramps. mouth. mulut kering. Psychological and physical dependence with withdrawal syndrome. Oedema associated with heart failure Adult: Usual dosage: 25100 mg daily in the morning. fatigue. perubahan salivasi. lethargy. jaundice. disuria. 12-18 yr: 10 mg (max: 40 mg/day). depresi. depresi napas dan SSP. acute narrow angle glaucoma. hyperglycaemia. photosensitivity. vomiting. inkontinensia. koma Palpitasi. ggn SSP. anuria. iskemik miokard.5 mg/hari Extract belladone 10 mg (Hyoscyamine) Spasme viseral Reserpine 0. mulut kering. anorexia.disease. colitis ulserativa. uropathy obstruktif. peningkatan BB. retensi Na. ataksia. konstipasi. ileus paralitik. galaktorrhea. Diazepam 2 mg PO Anxietas berat. sedasi. ggn penglihatan. Max: 30 mg daily. libido menurun. takikardia. konstipasi. pancreatitis. myasthenia gravis. constipation. colitis ulserativa berat. lactation. ggn GIT. laktasi Ulkus peptikum. edema. spasme otot Hipersensitivitas. kehamilan. laktasi Severe anxiety Adult: 2 mg tid. drowsiness. takikardia. sulphonamide allergy. pusing. cyclopegia. atoni intestinal pada lansia. perubahan napsu makan. drowsiness. keringat menurun Kongesti nasal. depresi atau koma SSP. insufisiensi paru akut. hesitansi. may precipitate an attack of gout. rash. urtikaria. thirst. penyakit GIT obstruktif. megakolon toksik. miosis.5 mg/kgBB/hari. 512 year: 5 mg. weakness. Up to 200 mg daily may be used as initial doses in severe cases. fatigue. nausea. vertigo. kembung. slurring of speech dan dysarthria. perubahan mental. preexisting hypercalcaemia. depresi napas. Dosis maks 1. hypotension. jaundice. if necessary.anak < 6 bln. Insomnia akibat anxietas Dewasa : 5-15 mg sblm tdr < 18 thn : : 1-5 mg sblm tdr Spasme otot Adult: 2-15 mg daily in divided doses Child: 1-12 mth: 250 mcg/kg. supresi laktasi. retensi urin. KV tidak stabil pada perdarahan. sleep apnoea syndrome. thrombocytopenia. perubahan libido. either alone or combined with other antihypertensives. alergi. Potentially Fatal: Hypersensitivity reactions. pruritus.5 mg. trombositopeni purpura daily. amnesia. 4x/hari Papaverin 40 mg Kolik kandung empedu & ginjal & kondisi dimana memerlukan relaksasi otot polos. weakness. hypersensitivity reactions e. insomnia akibat anxietas. terapi tambahan pada kejang.g. confusion. rashes. diarrhoea. impotensi. nyeri kepala. impotence. ataksia. raised Ca concentration. peningkatan enzim hepar. gastric irritation. kelemahan otot. up to 100 mg daily. psikosis Glaukoma. eksitasi paradoksikal. ginekomastia. Dose can be given twice daily. Pregnancy. TIO meningkat. breast engorgement. hipotensi. dizziness. impotensi.

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