rifampin + chloramphenicol rifampin decreases levels of chloramphenicol by increasing metabolism. Minor or nonsignificant interaction.

rifampin + sulfamethoxazole rifampin will decrease the level or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/10 metabolism. Minor or non-significant interaction. clotrimazole + rifampin clotrimazole decreases levels of rifampin by inhibition of GI absorption. Applies only to oral form of both agents. Minor or non-significant interaction. Only applies to oral preparations of both agents.

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