Chapter 5: Population Genetic

5.1 Gene Pool Concept Explain gene pool and allele frequency Explain population genetics and its relation to allele frequency Explain allele frequency and genetic equilibrium Describe the changes in allele frequency 5.2 Hardy-Weinberg Law State the Hardy-Weinberg Law Explain five assumptions of Hardy-Weinberg Law for genetic equilibrium. Using the Hardy-Weinberg equations to calculate alleles and genotype frequencies.

Chapter Review

Extra Exercise
Multiple Choice Question 1. A population is defined as __________. a. members of the same species, living in the same area, that have the potential to interbreed b. members of the same genus, living in the same area, that have the potential to interbreed c. interbreeding members of the same species d. members of the same species e. members of the same genus 2. Which of the following is NOT a condition of the Hardy-Weinberg law? a. Mating within the population occurs at random with respect to the loci under consideration. b. The population is infinitely large or, in practical terms, is large enough that sampling errors and random effects are negligible. c. No more than one other factor—mutation, migration, or random genetic drift—can be acting at one time during the period under study. d. There is no selective advantage for any of the genotypes under consideration; all genotypes are equally viable and fertile. e. All of the above are conditions of the Hardy-Weinberg law.

the frequency of S is p=0. 64% of giraffes have small spots. then the expected incidence of affected homozygous females would be _______. 1 in 20 b.9 0. d.3. and 100 were homozygous for its absence.55 0. What conditions must be meet for a population to be in Hardy-Weinberg Equilibrium? 2. If an autosomal recessive disorder which shows Hardy-Weinberg equilibrium has an incidence of 1 in 6400 then the frequency of carriers is approximately _______. the gene that determines spot size has two alleles. 1 in 120 5. a. What characterizes a population in Hardy-Weinberg equilibrium? Genetic Problem: 1. 1 in 80 d. 3. In a population of giraffes. Explain why population size is important to the Hardy-Weinberg Law. If an X-linked recessive disorder is in Hardy-Weinberg equilibrium and the incidence in males equals 1 in 100. 1 in 4000 c. a. 200 were homozygous for the presence of the restriction site. e. In one generation. What percentage of giraffes in the second generation will have medium spots? Large spots? . 1 in 40000 Short Answer: 1. Giraffes with one of each allele have mediumsized spots. 1 in 10000 d. All members of an isolated village were genotyped for a particular RFLP. 1 in 40 c.45 0. 0. Of the 1000 individuals. b. c. they are acted upon by natural selection.6. In the next generation. Since spots help the giraffes blend in with their surroundings.4 and the frequency of s is q=0. S for larger spots and s for smaller spots. 1 in 160 e. What is the frequency of the "restriction site present" allele. 1 in 1000 b. p? a.2 None of the above 4. What must be true of mating within a population for it to be in Hardy-Weinberg equilibrium? 4. 700 were heterozygous.

a. What is the predicted frequency of heterozygotes? c... how did the tidal wave affect the predicted frequencies of the alleles in the population? NOTE: assume the new population is at equilibrium -." . calculate the following: a.so you are comparing two populations what are at equilibrium to look for changes in allele frequencies. The frequency of the "a" allele. If 81% of a population is homozygous recessive for a given trait... The frequency of the "A" allele. d. If you have 168 brown mice in a population of 200 mice. What is the predicted frequency of heterozygotes? b.... e. b. What is the predicted frequency of homozygous dominant? c. a. c.2. What is the predicted frequency of homozygous dominant? 3. If we assume that all individuals were equally likely to be wiped out. What is the frequency of the dominant and recessive alleles in the population? 5... a. Using that 36%... a.. Lets say that brown fur coloring is dominant to gray fur coloring in mice. leaving 36 homozygous recessive out of the 100 survivors." The frequencies of the two possible phenotypes if "A" is completely dominant over "a. What is the predicted frequency of individuals in the population that express the dominant phenotype? b.. What is the predicted frequency of homozygous recessive? 4. What is the predicted frequency of homozygous dominant? b. If 51% of the population carries at least one copy of the recessive allele.... What is the frequency of homozygous recessive? b.... The frequency of the "aa" genotype. What is the predicted frequency of individuals in the population that express the recessive phenotype? 6..AFTER the event . Your original population of 200 was hit by a tidal wave and 100 organisms were wiped out... You have sampled a population in which you know that the percentage of the homozygous recessive genotype (aa) is 36%. The frequencies of the genotypes "AA" and "Aa. What is the predicted frequency of heterozygotes? c.

245 young "potential" Biology instructors. The expected genotype frequencies. 8. c. Within a population of butterflies. Assuming that all of the Hardy-Weinberg conditions are met. a. The frequency of the recessive allele in the population. "aa". and determined that 150 could detect the bitter taste of PTC and 65 could not.7. Please calculate the following. The frequency of the dominant allele in the population. b. The frequency of homozygous dominant individuals.500 babies in the Caucasian population of the United States. the color brown (B) is dominant over the color white (b). Cystic fibrosis is a recessive condition that affects about 1 in 2. Conditions happen to be really good this year for breeding and next year there are 1. And. b. Calculate allelic and genotypic frequencies for this population. Please calculate the following: a. Given this simple information. The allele frequencies of each allele. A rather large population of Biology instructors have 396 red-sided individuals and 557 tan-sided individuals. 11. 10. how many of these would you expect to be red-sided and how many tan-sided? 9. . b. The number of heterozygous individuals that you would predict to be in this population. e. The expected phenotype frequencies. Assume that red is totally recessive. The percentage of butterflies in the population that are heterozygous. c. The ability to taste PTC is due to a single dominate allele "T". d. A very large population of randomly-mating laboratory mice contains 35% white mice. which is something that is very likely to be on an exam. White coloring is caused by the double recessive genotype. calculate the following: a. You sampled 215 individuals in biology. The percentage of heterozygous individuals (carriers) in the population. Calculate all of the potential frequencies. 40% of all butterflies are white.

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