01: Mucoluoskeletal and Rehabilitation

Duff J, Evans MJ, Kennedy P. Goal planning: a retrospective audit of rehabilitation process and outcome. Clinical Rehabilitation 2004; 18(3):275-286. Elliott TR, Kennedy P. Treatment of Depression Following Spinal Cord Injury: An Evidence- Based Review. Rehabilitation Psychology 2004; 49(2):134-139. Tasiemski T, Kennedy P, Gardner BP, Blaikley RA. Athletic identity and sports participation in people with spinal cord injury. Adapted Physical Activity Quarterly 2004; 21(4):364-378. Chennagiri R, Burge P. Pre-osteotomy plate application technique for ulnar shortening. Journal of Hand Surgery 2004; 29(5):453-457. Herron ML, Kar S, Beard D, Binfield P. Sensory dysfunction in the great toe in hallux valgus. Journal of Bone and Joint Surgery-British Volume 2004; 86B(1):54-57. Harvie P, Ostlere SJ, Teh J, McNally EG, Clipsham K, Burston BJ et al. Genetic influences in the aetiology of tears of the rotator cuff - Sibling risk of a full-thickness tear. Journal of Bone and Joint Surgery-British Volume 2004; 86B(5):696-700. Herron ML, Kar S, Beard D, Binfield P. Sensory dysfunction in the great toe in hallux valgus. Journal of Bone and Joint Surgery-British Volume 2004; 86B(1):54-57 Linguraru MG, Brady M, English R. Foveal algorithm for the detection of microcalcification clusters: A FROC analysis. Medical Image Computing and Computer-Assisted Intervention - Miccai 2004, Pt 2, Proceedings 2004; 3217:813-820. Price AJ, Rees JL, Beard DJ, Gill RH, Christopher A, Murray DM. Sagittal plane kinematics of a mobile-bearing unicompartmental knee arthroplasty at 10 years: a comparative in vivo fluoroscopic analysis. Journal of Arthroplasty 2004; 19(5):590-597. Sato H, Lagan AL, Alexopoulou C, Vassilakis DA, Ahmad T, Pantelidis P et al. The TNF-863A allele strongly associates with anticentromere antibody positivity in scleroderma. Arthritis and Rheumatism 2004; 50(2):558-564. Williamson L, Dockerty JL, Dalbeth N, McNally E, Ostlere S, Wordsworth BP. Clinical assessment of sacroiliitis and HLA-B27 are poor predictors of sacroiliitis diagnosed by magnetic resonance imaging in psoriatic arthritis. Rheumatology 2004; 43(1):85-88. Dawson J, Linsell L, Zondervan K, Rose P, Randall T, Carr A et al. Epidemiology of hip and knee pain and its impact on overall health status in older adults. Rheumatology (Oxford) 2004;(43):4-497. Price JD, Sear JW, Venn RM. Perioperative fluid volume optimization following proximal femoral fracture. The Cochrane database of Systematic Reviews 1. 2004. Jaakkola E, Crane AM, Laiho K, Herzberg I, Sims AM, Bradbury L et al. The effect of transforming growth factor beta1 gene polymorphisms in ankylosing spondylitis. Rheumatology (Oxford) 2004; 43(1):32-38. Koay MA, Duncan EL, Ralston SH, Compston JE, Cooper C, Keen R et al. Influence of LRP5 gene polymorphisms on the normal variation of bone mineral density. J Bone Miner Res 2004; 19(6):1030. Williamson L, Dalbeth N, Dockerty JL, Gee BC, Weatherall R, Wordsworth BP. Extended report: nail disease in psoriatic arthritis--clinically important, potentially treatable and often overlooked. Rheumatology (Oxford) 2004; 43(6):790-794.

Williamson L, Dockerty JL, Dalbeth N, Wordsworth BP. Gastrointestinal disease and psoriatic arthritis. J Rheumatol 2004; 31(7):1469-1470. Williamson L, Dockerty JL, Dalbeth N. Treatment of psoriatic arthritis. Rheumatology (Oxford) 2004; 43(7):938-939. Adamopoulos I, Danks L, Sabokbar A, Carr A, Wordsworth BP, Athanasou NA. Synovial fluid promotes macrophage and osteoclast formation in inflammatory arthritis. J Bone Miner Res 2004; 19(6):1051. Aldinger PR, Clarius M, Murray DW, Goodfellow JW, Breusch SJ. Medial unicompartmental knee replacement using the "Oxford Uni" meniscal bearing knee. Orthopade 2004; 33(11):1277-1283. Barker KL, Simpson A-HRW. Recovery of function after closed femoral shortening. J Bone Joint Surg Am 2004; 86(8):1182-1186. Barker KL, Lamb SE, Simpson A-HRW. Functional recovery in patients with nonunion treated with the Ilizarov technique. J Bone Joint Surg Am 2004; 86(1):81-85. Barker KL, Shamley DR, Jackson D. Changes in the cross-sectional area of multifidus and psoas in patients with unilateral back pain: the relationship to pain and disability. Spine 2004; 29(22):515-519. Blair HC, Athanasou NA. Recent advances in osteoclast biology and pathological bone resorption. Histol Histopathol 2004; 19(1):189-199. Bond SE, Saeed NR, Cussons PD, Watt-Smith SR. Reconstruction of the temporomandibular joint by the transfer of the free vascularised second metatarsal. Br J Oral Maxillofac Surg 2004; 42(3):241245. Briggs A, Sculpher M, Dawson J, Fitzpatrick R, Murray- David, Malchau H. The use of probabilistic decision models in technology assessment : the case of total hip replacement. Applied Health Economics and Health Policy 2004; 3(2):79-89. Clarke R, Grimley EJ, Schneede J, Nexo E, Bates C, Fletcher- A et al. Vitamin B12 and folate deficiency in later life. Age Ageing 2004; 33(1):34-41. Edwards JR, Jackson DG, Athanasou NA. The role of lymphatics in tumour growth in bone. J Pathol 2004; 204:44A. Edwards JR, Sun SG, Shipman CM, Athanasou NA, Sabokbar A. Light, a TNF-superfamily member, induces osteoclast formation in vitro; A novel mediator of bone resorption? J Bone Miner Res 2004; 19(6):1051. Fairbank-Jeremy CT. William Adams and the spine of Gideon Algernon Mantell. Ann R Coll Surg Engl 2004; 86(5):349-352. Fairbank J. Historical perspective: William Adams, the forward bending test, and the spine of Gideon Algernon Mantell. Spine 2004; 29(17):1953-1955. Fang-Christopher SJ, McCarthy CL, McNally EG. Intramuscular dissection of Baker's cysts: report on three cases. Skeletal Radiol 2004; 33(6):367-371. Ferguson D-JP, Itonaga I, Maki M, McNally E, Gundle R, Athanasou NA. Heterotopic bone formation following hip arthroplasty in Paget's disease. Bone 2004; 34(6):1078-1083. Glyn JS, Gill HS, McLardy SP, Murray DW. Roentgen stereophotogrammetric analysis of the Birmingham hip resurfacing arthroplasty. A two-year study. J Bone Joint Surg Br 2004; 86(2):172-176.

Green J, Young J, Forster A, Collen F, Wade D. Combined analysis of two randomized trials of community physiotherapy for patients more than one year post stroke. Clin Rehabil 2004; 18(3):249252. Harrison JL, Ostlere SJ. Diagnosing purely ligamentous injuries of the cervical spine in the unconscious trauma patient. Br J Radiol 2004; 77(916):276-278. Harvie P, Patel N, Ostlere SJ. Prevalence and epidemiological variation of anomalous muscles at guyon's canal. J Hand Surg [Br] 2004; 29(1):26-29. Itonaga I, Sabokbar A, Sun SG, Kudo O, Danks L, Ferguson D et al. Transforming growth factor-beta induces osteoclast formation in the absence of RANKL. Bone 2004; 34(1):57-64. Johnson GR, Ferrarin M, Harrington M, Hermens H, Jonkers I, Mak P et al. Performance specification for lower limb orthotic devices. Clinical Biomechanics 2004; 19(7):711-718. Kellett CF, Short A, Price A, Gill HS, Murray DW. In vivo measurement of total knee replacement wear. Knee 2004; 11(3):183-187. Lau YS, Edwards J, Sabokbar A, Gibbons CLMH, Giele H, Athanasou NA. Sarcoma-associated macrophages differentiate into osteoclastic bone-resorbing cells. J Bone Miner Res 2004; 19(6):1051. Maki M, Athanasou N. Osteofibrous dysplasia and adamantinoma: correlation of proto-oncogene product and matrix protein expression. Hum Pathol 2004; 35(1):69-74. Matthews T, Carr A. Orthopaedic surgery and haemophilia. Current Orthopaedics 2004; 18(5):345356. McCarthy CL, McNally EG. The MRI appearance of cystic lesions around the knee. Skeletal Radiol 2004; 33(4):187-209. Rees JL, Price AJ, Beard DJ, Dodd C-AF, Murray DW. Minimally invasive Oxford unicompartmental knee arthroplasty: functional results at 1 year and the effect of surgical inexperience. Knee 2004; 11(5):363-367. Southam L, Dowling B, Ferreira A, Marcelline L, Mustafa Z, Chapman K et al. Microsatellite association mapping of a primary osteoarthritis susceptibility locus on chromosome 6p12.3-q13. Arthritis Rheum 2004; 50(12):3910-3914. Spencer-Jonathan MF, Gibbons C-LM, Sharp RJ, Andrew J, Athanasou NA. Arthroplasty for ochronotic arthritis: no failure of 11 replacements in 3 patients followed 6-12 years. Acta Orthop Scand 2004; 75(3):355-358. Teh J, Ostlere S. Diagnostic and therapeutic percutaneous procedures in the spine. Rivista di Neuroradiologia 2004; 17(3):362-368. Urban-Jill PG, Smith S, Fairbank-Jeremy CT. Nutrition of the intervertebral disc. Spine 2004; 29(23):2700-2709. Wilson D. Ultrasound assessment of carpal tunnel syndrome. Clin Radiol 2004; 59(10):909. Wilson DJ. Soft tissue and joint infection. Eur Radiol 2004; 14(3 Suppl):s64-s71. Zavatsky AB, Oppold PT, Price AJ. Simultaneous in vitro measurement of patellofemoral kinematics and forces. J Biomech Eng 2004; 126(3):351-356. Barker K, Lamb SE, Toye F, Jackson S, Barrington- Sharon. Association between radiographic joint space narrowing, function, pain and muscle power in severe osteoarthritis of the knee. Clin Rehabil 2004; 18(7):793-800.

Berendt T, Byren I. Bone and joint infection. Clinical Medicine 2004; 4(6):510-518 Johnson D, Tiernan E, Richards AM, Cole RP. Dynamic external fixation for complex intraarticularphalangeal fractures. Journal of Hand Surgery 2004; 29 B(1):76-81. Newton JL, Harney-Sinad MJ, Timms AE, Sims AM, Rockett K, Darke C et al. Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis. Arthritis Rheum 2004; 50(7):2122-2129. Ramsbottom R, Ambler A, Potter J, Jordan B, Nevill A, Williams C. The effect of 6 months training on leg power, balance, and functional mobility of independently living adults over 70 years old. Journal of Aging and Physical Activity 2004; 12(4):497-510. Robson MD, Gatehouse PD, Bydder GM, Neubauer S. Human imaging of phosphorus in cortical and trabecular bone in vivo. Magn Reson Med 2004; 51(5):888-892. Hands LJ, Jones RW, Clarke M, Mahaffey W, Bangs I. The use of telemedicine in the management of vascular surgical referrals. J Telemed Telecare 2004; 10(Suppl 1):38-40. Leardini A, O'Connor JJ, Catani F, Giannini S. Mobility of the human ankle and the design of total ankle replacement. Clin Orthop 2004;(424):39-46. Parenti-Castelli V, Leardini A, Di Gregorio R, O'Connor JJ. On the modeling of passive motion of the human knee joint by means of equivalent planar and spatial parallel mechanisms. Autonomous Robots 2004; 16(2):219-232. Williamson L, Dockerty JL, Dalbeth N, McNally E, Ostlere S, Wordsworth BP. Clinical assessment of sacroiliitis and HLA-B27 are poor predictors of sacroiliitis diagnosed by magnetic resonance imaging in psoriatic arthritis. Rheumatology 2004; 43[1], 85-88. Williamson L, Dalbeth N, Dockerty JL, Gee BC, Weatherall R, Wordsworth BP. Extended report: nail disease in psoriatic arthritis--clinically important, potentially treatable and often overlooked. Rheumatology 2004; 43[6], 790-794. Timms A, Crane A, Sims A, Cordell H, Bradbury L, Abbott A et al. The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. American Journal of Human Genetics 2004; 75[4], 587-595. Sims A, Wordsworth B, Brown M. Genetic susceptibility to ankylosing spondylitis. Current molecular medicine 2004; 4(1):13-20. Pattison DJ, Silman AJ, Goodson NJ, Lunt M, Bunn D, Luben R et al. Vitamin C and the risk of developing inflammatory polyarthritis: prospective nested case-control study. Ann Rheum Dis 2004; 63(7):843-847. Newton JL, Harney SMJ, Wordsworth BP, Brown MA. A review of the MHC genetics of rheumatoid arthritis. Genes and immunity 2004; 5(3):151-157. Jaakkola E, Crane AM, Laiho K, Herzberg I, Sims AM, Bradbury L et al. The effect of transforming growth factor beta1 gene polymorphisms in ankylosing spondylitis. Rheumatology 2004; 43[1], 32-38. Gleeson RE, Evans R, Ackroyd CE, Webb J, Newman JH. Fixed or mobile bearing unicompartmental knee replacement? A comparative cohort study. The Knee 2004; 11(5):379-384. Gennero I, Dickinson SC, Sims TJ, Espina B, Hulley PA, Hollander AP et al. Lovastatin stimulates type II collagen and glycoaminoglycan protein production in bovine articular chondrocytes. Bone 2004; 34:S34-S35.

Brogan PA, Shah V, Brachet C, Harnden A, Mant D, Klein N et al. Endothelial and platelet microparticles in vasculitis of the young. Arthritis Rheum 2004; 50(3):927-936. Appel H, Kuon W, Kuhne M, Wu PH, Kuhlmann S, Kollnberger S et al. Use of HLA-B27 tetramers to identify low-frequency antigen- specific T cells in Chlamydia-triggered reactive arthritis. Arthritis Research & Therapy 2004; 6(6):R521-R534. Bonifati DM, Willcox N, Vincent A, Beeson D. Lack of association between acetylcholine receptor epsilon polymorphisms and early-onset myasthenia gravis. Muscle Nerve 2004; 29(3):436-439. Dawson J, Linsell L, Zondervan K, Rose P, Randall T, Carr A et al. Epidemiology of hip and knee pain and its impact on overall health status in older adults. Rheumatology (Oxford) 2004; 43(4):497-504. De Raeve HR, Vermeulen PB, Vanderkerken K, Harris AL, Van Marck E. Microvessel density, endothelial-cell proliferation and carbonic anhydrase IX expression in haematological malignancies, bone-marrow metastases and monoclonal gammopathy of undetermined significance. Virchows Arch 2004; 445(1):27-35. Edwards JE, McQuay HJ, Moore RA. Efficacy and safety of valdecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials. Pain 2004; 111(3):286296. Fitzpatrick R, Norquist JM, Jenkinson C, Reeves BC, Morris RW, Murray DW et al. A comparison of Rasch with Likert scoring to discriminate between patients' evaluations of total hip replacement surgery. Qual Life Res 2004; 13(2):331-338. Fitzpatrick R, Norquist JM, Jenkinson C. Distribution-based criteria for change in health-related quality of life in Parkinson's disease. J Clin Epidemiol 2004; 57(1):40-44. Fitzpatrick R, Norquist JM, Reeves BC, Richard W, Murray DW, Gregg PJ. Equity and need when waiting for total hip replacement surgery. J Eval Clin Pract 2004; 10(1):3-9. Hajihosseini MK, Lalioti MD, Arthaud S, Burgar HR, Brown JM, Twigg SRF et al. Skeletal development is regulated by fibroblast growth factor receptor 1 signalling dynamics. Development 2004; 131(2):325-335. Hobart JC, Riazi A, Lamping DL, Fitzpatrick R, Thompson AJ. Improving the evaluation of therapeutic interventions in multiple sclerosis: development of a patient-based measure of outcome. Health Technol Assess 2004; 8(9):1-48. Gwilym SE, Swan MC, Giele H. One in 13 'oringinal' articles in the Journal of Bone and Joint Surgery are duplicate or fragmented publications. Journal of Bone and Joint Surgery Series B 2004; 86(5):743-745. Hambleton S, Valeyev N, V, Muranyi A, Knott V, Werner JM, McMichael AJ et al. Structural and functional properties of the human notch-1 ligand binding region. Structure 2004; 12(12):2173-2183. Khan AA, Rider OJ, Jayadev CU, Heras PC, Giele H, Goldacre M. The role of manual occupation in the aetiology of Dupuytren's disease in men in England and Wales. J Hand Surg [Br] 2004; 29(1):1214. Simpson AHRW, Lamb S, Roberts PJ, Gardner TN, Evans JG. Does the type of flooring affect the risk of hip fracture? Age Ageing 2004; 33(3):242-246.

02: Mental Health

Ballard CG, Thomas A, Fossey J, Lee L, Jacoby R, Lana MM et al. A 3-month, randomized, placebocontrolled, neuroleptic discontinuation study in 100 people with dementia: The neuropsychiatric inventory median cutoff is a predictor of clinical outcome. Journal of Clinical Psychiatry 2004; 65(1):114-119. Bantick RA, Montgomery AJ, Bench CJ, Choudhry T, Malek N, McKenna PJ et al. A positron emission tomography study of the 5-HT1A receptor in schizophrenia and during clozapine treatment. Journal of Psychopharmacology 2004; 18(3):346-354. Bellgrove MA, Collinson SL, Mattingly JB, Pantelis C, Fitzgerald PB, James-Anthony CD et al. Attenuation of perceptual asymmetries in patients with early-onset schizophrenia: Evidence in favour of reduced hemispheric differentiation in schizophrenia? Laterality: Asymmetires of Body, Brain & Cognition 2004; 9(1):79-91. Bennett-Levy-James, Westbrook-David, Fennell-Melanie, Cooper-Myra, Rouf-Khadj, Hackmann-Ann. Behavioural experiments: Historical and conceptual underpinnings. Cognitive behaviour therapy: Science and practice series, Oxford guide to behavioural experiments in cognitive therapy. Oxford University Press, 2004: 1-20. Bennewith-Olive, Gunnell-David, Peters-Tim-, Hawton K, House A. Variations in the hospital management of self harm in adults in England: Observational study. British Medical Journal 2004; 328(7448):1108-1109. Close H, Schuller S. Psychotic symptoms. Cognitive behaviour therapy: Science and practice series, Oxford guide to behavioural experiments in cognitive therapy. Oxford University Press, 2004: 245263. Cooper-Myra, Whitehead-Linette, Boughton-Nicky. Eating disorders. Cognitive behaviour therapy: Science and practice series, Oxford guide to behavioural experiments in cognitive therapy. Oxford University Press, 2004: 267-284. Cooper MJ, Wells A, Todd G. A cognitive model of bulimia nervosa. British Journal of Clinical Psychology 2004; 43(1):1-16. de-Rosnay-Marc, Pons-Francisco, Harris-Paul-, Morrell J. A lag between understanding false belief and emotion attribution in young children: Relationships with linguistic ability and mothers' mentalstate language. British Journal of Developmental Psychology 2004; 22(2):197-218. Elphick M. National electronic care records for the UK - Will IT work for mental health services? European Psychiatry 2004; 19:108S-109S. Fazel S, Grann M. Psychiatric morbidity among homicide offenders: A Swedish population study. American Journal of Psychiatry 2004; 161(11):2129-2131. Fazel S, Hope T, Donnell I, Jacoby R. Unmet treatment needs of older prisoners: a primary care survey. Age and Ageing 2004; 33(4):396-398. Fazel S. Homicide offenders and psychiatric morbidity: A swedish population study. Schizophrenia Research 2004; 67(1):10-11. Geddes JR, Burgess S, Hawton K, Jamison K, Goodwin GM. Long-term lithium therapy for bipolar disorder: Systematic review and meta-analysis of randomized controlled trialls. American Journal of Psychiatry 2004; 161(2):217-222.

Gijsman HJ, Geddes JR, Rendell JM, Nolen WA, Goodwin GM. Antidepressants for bipolar depression: A systematic review of randomized, controlled trials. American Journal of Psychiatry 2004; 161(9):1537-1547. Grann M, Fazel S. Substance misuse and violent crime: Swedish population study. British Medical Journal 2004; 328(7450):1233-1234. Harmer CJ, Shelley NC, Cowen PJ, Goodwin GM. Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition. American Journal of Psychiatry 2004; 161(7):1256-1263. Harmer CJ, Mackay C, Reid CB, Cowen P, Goodwin G. Antidepressant drug treatment modifies subliminal emotional processing in the amygdala. Journal of Psychopharmacology 2004; 18(3):A12. Harmer CJ. Monoamines and emotional processing. Journal of Psychopharmacology 2004; 18(3):A73. Hawton-Keith, Harriss-Louise, Simkin-Sue, Bale-Elizabeth, Bond-Alison. Self-Cutting: Patient Characteristics Compared with Self-Poisoners. Suicide & Life Threatening Behavior 2004; 34(3):199208. Hawton K, Simkin S, Decks J, Cooper J, Johnston A, Waters K et al. UK legislation on analgesic packs: Before and after study of long term effect on poisonings. British Medical Journal 2004; 329(7474):1076-1079. Hawton K, Zahl D, Weatherall R, Tyrer P. The risk of suicide after deliberate self harm was significant and persistent over the long term. Evidence Based Medicine 2004; 9(2):59. Hawton K, Harriss L, Simkin S, Bale E, Bond A. Suicidal Behaviour in England and Wales. In: Shcmidtke-Armin E, editor. Suicidal behaviour in Europe: Results from the WHO/EURO multicentre Study on Suicidal Behaviour. Hogrefe & Huber, 2004: 123-131. Hawton K, Malmberg A, Simkin S. Suicide in doctors - A psychological autopsy study. Journal of Psychosomatic Research 2004; 57(1):1-4. Henderson M, Bass C, Poole J. Occupational psychiatry. British Journal of Psychiatry 2004; 184:362. James A, Lai FH, Dahl C. Attention deficit hyperactivity disorder and suicide: a review of possible associations. Acta Psychiatrica Scandinavica 2004; 110(6):408-415. James AC, James S, Smith DM, Javaloyes A. Cerebellar, prefrontal cortex, and thalamic volumes over two time points in adolescent-onset schizophrenia. American Journal of Psychiatry 2004; 161(6):1023-1029. Mannie Z, McTavish S, Harmer C, Cowen P. Tyrosine depletion in recovered depressed women. Journal of Psychopharmacology 2004; 18(3):A16. McGowan S, Lawrence AD, Sales T, Quested D, Grasby PM. Presynaptic dopaminergic dysfunction in schizophrenia: A positron emission tomographic (-sup-8F) fluorodopa study. Archives of General Psychiatry 2004; 61(2):134-142. McShane RH. Memantine plus donepezil improves physical and mental health in people with Alzheimer's disease. Evidence Based Mental Health 2004; 7(3):76. Morgan J, Hawton K. Self-Reported Suicidal Behavior in Juvenile Offenders in Custody: Prevalence and Associated Factors. Crisis 2004; 25(1):8-11. Murray B. Castles in the air: Civilian trainee experiences with the RAF. Psychiatric Bulletin 2004; 28(4):145-146.

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Hafizi S, Serres F, Pei Q, Totterdell S, Grasby P, Sharp T. Evidence for co-localisation of neurokinin1 and 5-HT1A receptors in pat forebrain. Journal of Psychopharmacology 2004; 18(3):A28. Sharpley AL, Attenburrow MEJ, Hafizi S, Cowen PJ. Olanzapine increases slow wave sleep in SSRI resistant depressed patients. Journal of Psychopharmacology 2004; 18(3):A14. Rodham-Karen, Hawton-Keith, Evans-Emma. Reasons for deliberate self-harm: Comparison of selfpoisoners and self-cutters in a community sample of adolescents. Journal of the American Academy of Child and Adolescent Psychiatry 2004; 43(1):80-87. Gardner F, Johnson A, Yudkin P, Bowler U, Hockley- Christine, Mutch L et al. Behavioral and emotional adjustment of teenagers in mainstream school who were born before 29 weeks' gestation. Pediatrics 2004; 114(3):676-682. Montgomery P, Dennis J. A systematic review of non-pharmacological therapies for sleep problems in later life. Sleep Medicine Reviews 2004; 8(1):47-62. Brylewski J, Duggan L. Antipsychotic medication for challenging behaviour in people with learning disability. The Cochrane database of Systematic Reviews 3. 2004. Pollock LR, Williams JMG. Problem-solving in suicide attempters. Psychol Med 2004; 34(1):163-167. Reilly S, Challis D, Burns A, Hughes J. The use of assessment scales in Old Age Psychiatry Services in England and Northern Ireland. Aging and Mental Health 2004; 8(3):249-255. Talbot K, Eidem WL, Tinsley CL, Benson MA, Thompson EW, Smith RJ et al. Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. J Clin Invest 2004; 113(9):1353-1363. Williams JMG. Mindfulness-based cognitive therapy for depression: A new approach to preventing relapse. European Psychiatry 2004; 19:76S. Williams JM. Experimental cognitive psychology and clinical practice: Autobiographical memory as a paradigm case. Theoretical, Empirical and Clinical Directions. New York: Cambridge University Press, 2004: 251-269. Williams JM. The Use of Mindfulness-Based Approaches for Suicidal Patients. Archives of Suicide Research 2004; 8(4):315-329. Geddes J. Relapse prevention in bipolar disorder: the contribution of systematic reviews and metaanalyses. Acta Psychiatr Scand 2004; 110:8. Geddes JR, Cipriani A. Selective serotonin reuptake inhibitors. Br Med J 2004; 329(7470):809-810. Geddes JR. Bipolar disorder. Am Fam Physician 2004; 69(7):1715-1717. Lee M, Shafran R, Fairburn CG. Attentional biases in eating disorders: Assessment using an enhanced methodology. Int J Eat Disord 2004; 35(4):059. Lee M, Shafran R. Information processing biases in eating disorders. Clin Psychol Rev 2004; 24(2):215-238. Mackay CE, Robson MD, Cugno S, Connell J, van Aarde JB, Crow TJ et al. Brain torque relates to laterality of motor function but not hand preference. Schizophr Res 2004; 67(1):85. Mackay CE, Cugno S, Robson MD, Connell J, Clark G, Roberts N et al. Measurement of laterality using functional MRI. Schizophr Res 2004; 67(1):90.

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Knies-Bamforth UE, Fox SB, Poulsom R, Evan G, Harris AL. c-Myc interacts with hypoxia to induce angiogenesis in vivo by a vascular endothelial growth factor-dependent mechanism. Cancer Res 2004; 64(18):6563-6570. Knowles HJ, Ratcliffe PJ, Harris AL. Differentiation modulates the hypoxia-inducible gene program in macrophages: Effects of alterations in iron homeostasis. Br J Cancer 2004; 91:S17. Knowles H, Leek R, Harris AL. Macrophage infiltration and angiogenesis in human malignancy. Novartis Found Symp 2004; 256:189-200. Koukourakis MI, Giatromanolaki A, Sivridis E, Pastorek J, Karapantzos I, Gatter KC et al. Hypoxiaactivated tumor pathways of angiogenesis and pH regulation independent of anemia in head-andneck cancer. International Journal of Radiation Oncology Biology Physics 2004; 59(1):67-71. Liggins AP, Guinn BA, Hatton CS, Pulford K, Banham AH. Serologic detection of diffuse large B-cell lymphoma-associated antigens. Int J Cancer 2004; 110(4):563-569. Littlewood T. Medical uses of erythropoietin. Vox Sang 2004; 87(Suppl 2):93-95. Lowndes SA, Harris AL. Copper chelation as an antiangiogenic therapy. Oncol Res 2004; 14(1112):529-539. Madhusudan S, Foster M, Muthuramalingam SR, Braybrooke JP, Wilner S, Kaur K et al. A phase II study of etanercept (Enbrel), a tumor necrosis factor alpha inhibitor in patients with metastatic breast cancer. Clin Cancer Res 2004; 10(19):6528-6534. Muthuramalingam SR, Madhusudan S, Vasey PA, Patel P, Christodolus K, Protheroe A et al. A randomised phase II study of interferon-a alone or in combination with thalidomide in metastatic renal cell carcinoma. Br J Cancer 2004; 91:S33. Nijsten T, Colpaert CG, Vermeulen PB, Harris AL, Van Marck E, Lambert J. Cyclooxygenase-2 expression and angiogenesis in squamous cell carcinoma of the skin and its precursors: a paired immunohistochemical study of 35 cases. Br J Dermatol 2004; 151(4):837-845. Plugge E, Fitzpatrick R. Factors affecting cervical screening uptake in prisoners. J Med Screen 2004; 11(1):48-49. Potter C, Harris AL. Hypoxia inducible carbonic anhydrase IX, marker of tumor hypoxia, survival pathway and therapy target. Cell Cycle 2004; 3(2):164-167. Robertson N, Potter C, Harris AL. Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion. Cancer Res 2004; 64(17):6160-6165. Rossi JF, Van Hoof A, De Boeck K, Johnson SA, Bron D, Foussard C et al. Efficacy and safety of oral fludarabine phosphate in previously untreated patients with chronic lymphocytic leukemia. J Clin Oncol 2004; 22(7):1260-1267. Stephen RL, Gustafsson MCU, Jarvis M, Tatoud R, Marshall BR, Knight D et al. Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines. Cancer Res 2004; 64(9):3162-3170. Stessels F, Van den Eynden G, Van der Auwera I, Salgado R, Van den Heuvel E, Harris AL et al. Breast adenocarcinoma liver metastases, in contrast to colorectal cancer liver metastases, display a non-angiogenic growth pattern that preserves the stroma and lacks hypoxia. Br J Cancer 2004; 90(7):1429-1436. Swinson DEB, Jones JL, Cox G, Richardson D, Harris AL, O'Byrne KJ. Hypoxia-inducible factor-1 alpha in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways. Int J Cancer 2004; 111(1):43-50.

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Swinson S, Hall G, Pollard AJ. Reactivation of the bacille Calmette-Gurin scar following immune reconstitution during treatment of infant acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2004; 26(2):112-115. Van den Eynden GG, Van der Auwera I, Van Laere S, Colpaert CG, van Dam P, Merajver S et al. Validation of a tissue microarray to study differential protein expression in inflammatory and noninflammatory breast cancer. Breast Cancer Res Treat 2004; 85(1):13-22. Wall L, Talbot DC, Bradbury P, Jodrell DI. A phase I and pharmacological study of the matrix metalloproteinase inhibitor BB-3644 in patients with solid tumours. Br J Cancer 2004; 90(4):800-804. Wykoff CC, Sotiriou C, Cockman ME, Ratcliffe PJ, Maxwell P, Liu E et al. Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene. Br J Cancer 2004; 90(6):1235-1243. Behrenbruch CP, Marias K, Armitage PA, Yam M, Moore NR, English R et al. Fusion of contrastenhanced breast MR and mammographic imaging data. Br J Radiol 2004; 77(2):s201-s208. Bianchi F, Hu J, Pelosi G, Cirincione R, Ferguson M, Ratcliffe C et al. Lung cancers detected by screening with spiral computed tomography have a malignant phenotype when analyzed by cDNA microarray. Clin Cancer Res 2004; 10(18):6023-6028. Bordea C, Wojnarowska F, Millard PR, Doll H, Welsh K, Morris PJ. Skin cancers in renal-transplant recipients occur more frequently than previously recognized in a temperate climate. Transplantation 2004; 77(4):574-579. Wheeler J-MD, Dodds E, Warren BF, Cunningham C, George BD, Jones A et al. Preoperative chemoradiotherapy and total mesorectal excision surgery for locally advanced rectal cancer: correlation with rectal cancer regression grade. Dis Colon Rectum 2004; 47(12):2025-2031. Winter S-CA, Cassell O, Corbridge RJ, Goodacre T, Cox GJ. Quality of life following resection, free flap reconstruction and postoperative external beam radiotherapy for squamous cell carcinoma of the base of tongue. Clin Otolaryngol 2004; 29(3):274-278. Chakrabarti J, Turley H, Campo L, Han C, Harris AL, Gatter KC et al. The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. Br J Cancer 2004; 91(5):954-958. Yudkin P, Munaf M, Hey K, Roberts S, Welch S, Johnstone E et al. Effectiveness of nicotine patches in relation to genotype in women versus men: Randomised controlled trial. British Medical Journal 2004; 328(7446):989-990. Mouchel N, Henstra SA, McCarthy VA, Sarah H, Phylactides M, Harris A. HNF1alpha is involved in tissue-specific regulation of CFTR gene expression. Biochem J 2004; 378(3):909-918. Barnes E, Salio M, Cerundolo V, Medlin J, Murphy S, Dusheiko G et al. Impact of alpha interferon and ribavirin on the function of maturing dendritic cells. Antimicrob Agents Chemother 2004; 48(9):33823389. Fearnhead NS, Wilding JL, Winney B, Tonks S, Bartlett S, Bicknell DC et al. Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proc Natl Acad Sci USA 2004; 101(45):15992-15997.

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04: Cardiovascular
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Hasan S, Ratnatunga C, Lewis CT, Pillai R. Gut ischaemia following cardiac surgery. Interactive Cardiovascular and Thoracic Surgery 2004; 3(3):475-478. Jin XY. Elucidation of cardiac, physiology in aortic valve replacement: What should we know? Journal of Heart Valve Disease 2004; 13:S70-S75. Kattach H, Anastasiadis K, Jin XY, Pillai R. Two-conduit repair for anomalous origin of the left coronary artery from the pulmonary artery in an adult. Journal of Thoracic and Cardiovascular Surgery 2004; 128(4):641-642. Khoo J, Zhao L, Alp NJ, Bendall J, Nicoli T, Wilkins MR et al. Tetrahydrobiopterin deficiency causes pulmonary hypertension: Effects on lung superoxide levels, hypoxic pulmonary vasoconstriction and vascular remodelling. Heart 2004; 90:150. Mussa S, Leeson P, Taggart DP, Channon KM. Pre-operative flow mediated dilatation predicts in vitro endothelial function in human radial artery. Heart 2004; 90:091. Nicolson DG, Porto I, Westaby S, Boardman P, Banning AP. Spontaneous echocardiographic contrast in the ascending aorta mimicking the appearance of aortic dissection in a patient with a left ventricular assist device. Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques 2004; 21(2):193-195. Porto I, MacDonald S, Banning AP. Intravascular ultrasound as a significant tool for diagnosis and management of coronary aneurysms. Cardiovascular and Interventional Radiology 2004; 27(6):666668. Selvanayagam JB, Kardos A, Francis J, Petersen S, Wiesmann F, Taggart DP et al. Effects of offpump versus on-pump coronary surgery on early and late postoperative left ventricular function: A randomized trial using cardiovascular magnetic resonance imaging. Journal of the American College of Cardiology 2004; 43(5):370A. Taggart D. Long-term follow-up of coronary artery bypass grafting in three-vessel disease using exclusively pedicled bilateral internal thoracic and right gastroepiploic arteries: Invited commentary. Annals of Thoracic Surgery 2004; 77(3):799, ISSN-4975. Taggart D. Off-pump surgery and cerebral injury. Journal of Thoracic and Cardiovascular Surgery 2004; 127(1):7-9. West NEJ, Chamberlain-Webber R, Banning AP. Which patients can safely undergo percutaneous coronary intervention (PCI) without onsite surgical cover? Heart 2004; 90:037. Westaby S. Coronary revascularization in ischemic cardiomyopathy. Surgical Clinics of North America 2004; 84(1):179-199. Westaby S. Ventricular assist devices as destination therapy. Surgical Clinics of North America 2004; 84(1):91-123. Westaby S, Narula J. Surgical options in heart failure. Surgical Clinics of North America 2004; 84(1):xv-xix. Dawson D, Lygate CA, Saunders J, Schneider JE, Ye XJ, Hulbert K et al. Quantitative 3-dimensional echocardiography for accurate and rapid cardiac phenotype characterization in mice. Circulation 2004; 110(12):1632-1637. Frayn KN, Ardilouze JL, Fielding BA, Karpe F. Coupling of metabolism and cardiovascular responses. Clinical Science 2004; 106(5):547-548. Parker KK, Lavelle JA, Taylor LK, Wang ZF, Hansen DE. Stretch-induced ventricular arrhythmias during acute ischemia and reperfusion. Journal of Applied Physiology 2004; 97(1):377-383.

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Jin XY, Hu JT, Pezzella F, Pepper J. Gene expression profiling and cardiac remodelling: Comparison of pressure versus volume overloaded human left ventricle. Heart 2004; 90:168. Lowe GDO, Danesh J, Lewington S, Walker M, Lennon L, Thomson A et al. Tissue plasminogen activator antigen and coronary heart disease. Eur Heart J 2004; 25(3):252-259. Danson E-JF, Mankia KS, Golding S, Dawson T, Everatt L, Cai S et al. Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele. J Physiol (Lond) 2004; 558(3):963-974. McCann FJ, Slade MG, Stradling J. Atrial septostomy in the treatment of severe pulmonary arterial hypertension. Thorax 2004; 59(5):450. Robinson GV, Pepperell J-CT, Segal HC, Davies R-JO, Stradling JR. Circulating cardiovascular risk factors in obstructive sleep apnoea: data from randomised controlled trials. Thorax 2004; 59(9):777-782. Robinson G, V, Stradling JR, Davies R-JO. Obstructive sleep apnoea/hypopnoea syndrome and hypertension. Thorax 2004; 59(12):1089-1094. Robinson G, V, Kanji H, Davies R-JO, Gleeson F, V. Selective pulmonary fat aspiration complicating oesophageal achalasia. Thorax 2004; 59(2):180. Sears CE, Ashley EA, Casadei B. Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component? Philos Trans R Soc Lond B Biol Sci 2004; 359(1446):1021-1044. Anderson KJ, Sear JW. QTc dispersion is prolonged in patients with early postoperative adverse cardiovascular events and those with silent myocardial ischemia. J Cardiothorac Vasc Anesth 2004; 18(3):281-287. Howell SJ, Sear JW, Young JD. Cardiovascular medicine and Moore's Law. Br J Anaesth 2004; 93(1):1-2. Howell SJ, Sear JW. Perioperative myocardial injury: individual and population implications. Br J Anaesth 2004; 93(1):3-8. Loke YK, Derry S, Aronson JK. A comparison of three different sources of data in assessing the frequencies of adverse reactions to amiodarone. Br J Clin Pharmacol 2004; 57(5):616-621. Refsum H, Smith AD, Ueland PM, Nexo E, Clarke R, McPartlin J et al. Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 2004; 50(1):3-32. Sear JW. Hypertension and postoperative cardiac mortality in non-cardiac surgical patient. Br J Anaesth 2004; 92(2):305-306. Xu H, Edwards JR, Espinosa O, Banerji S, Jackson DG, Athanasou NA. Expression of a lymphatic endothelial cell marker in benign and malignant vascular tumors. Hum Pathol 2004; 35(7):857-861. Young JD. The heart and circulation in severe sepsis. Br J Anaesth 2004; 93(1):114-120. Bamforth SD, Bragana J, Farthing CR, Jrgen E, Broadbent C, Michell AC et al. Cited2 controls leftright patterning and heart development through a Nodal-Pitx2c pathway. Nat Genet 2004; 36(11):1189-1196. Clarke N-RA, Timperley J, Kelion AD, Banning AP. Transthoracic echocardiography using second harmonic imaging with Valsalva manoeuvre for the detection of right to left shunts. European Journal of Echocardiography 2004; 5(3):176-181.

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Dawson D, Lygate CA, Saunders J, Schneider JE, Ye- Xujiong, Hulbert K et al. Quantitative 3dimensional echocardiography for accurate and rapid cardiac phenotype characterization in mice. Circulation 2004; 110(12):1632-1637 Dorrington KL, Talbot NP. Human pulmonary vascular responses to hypoxia and hypercapnia. Pflugers Archiv-European Journal of Physiology 2004; 449(1):1-15. Francis J, Cooke F, Bradley JL, Blamire AM, Schapira AHV, Neubauer S et al. Myocardial. hypertrophy in Friedreich's ataxia (FA) is a function of duration of the disease and the length of the GAA trinucleotide repeat; A cross sectional MRI study. Heart 2004; 90:201. Howell SJ, Sear JW, Foex P. Hypertension, hypertensive heart disease and perioperative cardiac risk. Br J Anaesth 2004; 92(4):570-583. Hu K, Naumann A, Fraccarollo D, Gaudron P, Kaden JJ, Neubauer S et al. Heart rate reduction by zatebradine reduces infarct size and mortality but promotes remodeling in rats with experimental myocardial infarction. American Journal of Physiology-Heart and Circulatory Physiology 2004; 286(4):H1281-H1288. McAteer MA, Schneider JE, Channon KM, Neubauer S, Choudbury RP. Very high resolution isotropic MRI enables 3D visualisation and quantification of lipid rich atherosclerotic plaques in the brachiocephalic artery of apo E-/- mice. Heart 2004; 90:149. Moorjani N, Catarino PA, Kemp TJ, Westaby S, Sugden PH. Volume overload induces activation of both mitochondrial and death receptor mediated pathways in the transition to human left ventricular (LV) failure. Heart 2004; 90:074. Murray AJ, Lygate CA, Cole MA, Neubauer S, Clarke K. Insulin resistance, abnormal energy metabolism and increased inschaemic damage in the chronically infracted rat heart. Cardiovascular Journal of South Africa 2004; 15(4 Suppl 1):s14. Petersen SE, Selvanayagam JB, Francis JM, Wiesmann F, Myerson S, Robson MD et al. Are geometric indices, derived from cardiac magnetic resonance (CMR) able to differentiate various forms of cardiac hypertrophy? Heart 2004; 90:210. Petersen SE, Mohrs OK, Horstick G, Oberholzer K, Abegunewardene N, Ruetzel K et al. Influence of contrast agent dose and image acquisition timing on the quantitative determination of nonviable myocardial tissue using delayed contrast-enhanced magnetic resonance imaging. Journal of Cardiovascular Magnetic Resonance 2004; 6(2):541-548. Sandstede JJW, Hillenbrand H, Beer M, Pabst T, Butter F, Machann W et al. Time course of Na-23 signal intensity after myocardial infarction in humans. Magn Reson Med 2004; 52(3):545-551. Schneider JE, Hulbert KJ, Lygate CA, ten Hove M, Cassidy PJ, Clarke K et al. Long-term stability of cardiac function in normal and chronically failing mouse hearts in a vertical-bore MR system. MAGMA 2004; 17(3-6):162-169. Schneider JE, McAteer MA, Tyler DJ, Clarke K, Channon KM, Choudhury RP et al. High-resolution, multicontrast three-dimensional-MRI characterizes atherosclerotic plaque composition in ApoE-/- mice ex vivo. J Magn Reson Imaging 2004; 20(6):981-989. Selvanayagam JB, Porto I, Petersen SE, Channon K, Neubauer S, Banning A. Do raised cardiac markers following percutaneous coronary intervention (PCI) really reflect cardiac necrosis. Heart 2004; 90:001. Selvanayagam JB, Kardos A, Nicolson D, Francis J, Petersen SE, Robson M et al. Anteroseptal or apical myocardial infarction: a controversy addressed using delayed enhancement cardiovascular magnetic resonance imaging. Journal of Cardiovascular Magnetic Resonance 2004; 6(3):653-661.

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Balacumaraswami L, Abu O, Anastasiadis K, Choudhary B, Pigott D, Yeong S et al. Does off-pump total arterial grafting increase the incidence of intraoperative graft failure? J Thorac Cardiovasc Surg 2004; 128(2):238-244. Balacumaraswami L, Yeong SK, Pigott D, Evans R, Robson M, Neubauer S et al. Validation of flow quantification using fluorescence imaging system for intraoperative coronary artery bypass graft (CABG) assessment. Heart 2004; 90:092. Aronson JK. Live long and prosper: A mass strategy for treating the factors associated with ischaemic heart disease and stroke. J Med Screen 2004; 11(1):1-2. Alp NJ, Channon KM. Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease. Arterioscler Thromb Vasc Biol 2004; 24(3):413-420. Bendall JK, Alp NJ, Nicoli TK, Rockett KA, Kawashima S, Yokoyama M et al. Endothelial tetrahydrobiopterin regulates eNOS coupling/uncoupling independent of vascular disease: Insights from targeted transgenic models. Heart 2004; 90(12):3. Bickerton A, Roberts R, Fielding B, Blaak E, Wagenmakers AJM, Gilbert M et al. Fatty acid oxidation in the metabolic syndrome. Atherosclerosis 2004; 175(2):S7. Bicknell R, Harris AL. Novel angiogenic signaling pathways and vascular targets. Annu Rev Pharmacol Toxicol 2004; 44:219-238. Bond R, Rerkasem K, Naylor AR, Aburahma AF, Rothwell PM. Systematic review of randomized controlled trials of patch angioplasty versus primary closure and different types of patch materials during carotid endarterectomy. J Vasc Surg 2004; 93(22):221101. Bond R, Rerkasem K, Aburahma AF, Naylor AR, Rothwell PM. Patch angioplasty versus primary closure for carotid endarterectomy. The Cochrane Database of Systematic Reviews 2. 2004. Bond R, Fairhead JF, Rerkasem K, Rothwell PM. A systematic review of the associations between age and sex and the operative risk of carotid endarterectomy. Stroke 2004; 35(6):E333. Bursill C, Greaves D, Channon KM. Adenoviral delivery of CC-chemokine inhibitor '35K' reduces macrophage recruitment and atherosclerosis in ApoE knockout mice. Atherosclerosis 2004; 174(1):S3. Bursill CA, Choudhury RP, Ali Z, Greaves DR, Channon KM. Broad-spectrum CC-chemokine blockade by gene transfer inhibits macrophage recruitment and atherosclerotic plaque formation in apolipoprotein E-knockout mice. Circulation 2004; 110(16):2460-2466. Bursill CA, Channon KM, Greaves DR. The role of chemokines in atherosclerosis: recent evidence from experimental models and population genetics. Curr Opin Lipidol 2004; 15(2):145-149. Cai S, Khoo J, Mussa S, Alp NJ, Channon KM. Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation. Heart 2004; 90(Suppl.2):28. Cattaruzza M, Guzik TJ, Slodowski W, Pelvan A, Becker J, Halle M et al. Shear stress insensitivity of endothelial nitric oxide synthase expression as a genetic risk factor for coronary heart disease. Circ Res 2004; 95(8):841-847. Channon KM. Tetrahydrobiopterin regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc Med 2004; 14(8):323-327. Danson E-JF, Mankia KS, Golding S, Dawson T, Everatt L, Cai S et al. Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele. J Physiol (Lond) 2004; 82(3):251-254.

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Khoo JP, Nicoli T, Alp NJ, Fullerton J, Flint- Jonathan, Channon KM. Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse. Mol Genet Metab 2004; 82(3):251-254. Lovett JK, Gallagher PJ, Hands LJ, Walton J, Rothwell PM. Histological correlates of carotid plaque surface morphology on lumen contrast imaging. Circulation 2004; 110(15):2190-2197. Lovett JK, Gallagher PJ, Rothwell PM. Reproducibility of histological assessment of carotid plaque: implications for studies of carotid imaging. Cerebrovasc Dis 2004; 18(2):117-123. Lovett JK, Redgrave JNF, Gallagher PJ, Rothwell PM. Pathological features of symptomatic carotid plaque and clinical correlates: A detailed histological study of 565 plaques. Stroke 2004; 35(6):E208. McAteer MA, Schneider JE, Clarke K, Neubauer S, Channon KM, Choudhury RP. Quantification and 3D reconstruction of atherosclerotic plaque components in apolipoprotein E knockout mice using ex vivo high- resolution MRI. Arterioscler Thromb Vasc Biol 2004; 24(12):2384-2390. Ng D, Thakker N, Corcoran CM, Donnai D, Perveen R, Schneider A et al. Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR. Nat Genet 2004; 36(4):411-416. Porto I, Blackman DJ, Nicolson D, Niccoli G, Kahn FZ, Ormerod O et al. What is the incidence of myocardial necrosis in elective patients discharged on the same day following percutaneous coronary intervention? Heart 2004; 90(12):1489-1490. Schneider JE, McAteer MA, Tyler DJ, Clarke K, Channon KM, Choudhury RP et al. High-resolution, multicontrast three-dimensional-MRI characterizes atherosclerotic plaque composition in ApoE-/- mice ex vivo. J Magn Reson Imaging 2004; 20(6):981-989 Selvanayagam JB, Porto I, Petersen SE, Channon K, Neubauer S, Banning A. Do raised cardiac markers following percutaneous coronary intervention (PCI) really reflect cardiac necrosis. Heart 2004; 90(Suppl.2):1. Wang Q, Robson MD, Francis JM, Petersen SE, Channon KM, Neubauer S et al. Accuracy of quantitative MR vessel wall imaging applying a semi- automated gradient detection algorithm--a validation study. Journal of Cardiovascular Magnetic Resonance 2004; 6(4):895-907. Wiesmann F, Petersen SE, Leeson PM, Francis JM, Robson MD, Wang Q et al. Global impairment of brachial, carotid, and aortic vascular function in young smokers: direct quantification by highresolution magnetic resonance imaging. J Am Coll Cardiol 2004; 44(10):2056-2064. Abu OY, Cifelli A, Matthews PM, Taggart DP. The role of microembolisation in cerebral injury as defined by functional magnetic resonance imaging. Eur J Cardiothorac Surg 2004; 26(3):586-591. Channon KM, Watkins H. Coronary artery disease genetics: Bigger is better. Eur Heart J 2004; 25(11):900-901. Flashman E, Redwood C, Moolman SJ, Watkins H. Cardiac myosin binding protein C: its role in physiology and disease. Circ Res 2004; 94(10):1279-1289. Neil H-AW, Seagroatt V, Betteridge DJ, Cooper MP, Durrington PN, Miller JP et al. Established and emerging coronary risk factors in patients with heterozygous familial hypercholesterolaemia. Heart 2004; 90(12):1431-1437. Schneider JE, Tyler DJ, Ten Hove M, Sang AE, Cassidy PJ, Fischer A et al. In vivo cardiac (1)H-MRS in the mouse. Magn Reson Med 2004; 52(5):1029-1035. Watkins H. A trio family study showing association of the lymphotoxin-(alpha) N26 (804A) allele with coronary artery disease. Eur J Hum Genet 2004; 12(9):770-774.

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Watkins H. Should genetic testing become a standard component of clinical trials in order to advance evidence-based cardiology practice? Dialogues in Cardiovascular Medicine 2004; 9(1):36-43. Mussa S, Prior T, Alp N, Wood K, Channon KM, Taggart DP. Duration of action of antispasmodic agents: novel use of a mouse model as an in vivo pharmacological assay. Eur J Cardiothorac Surg 2004; 26(5):988-994. Hillsdon M, Thorogood M, Murphy M, Jones L. Can a simple measure of vigorous physical activity predict future mortality? Results from the OXCHECK study. Public Health Nutrition 2004; 7(4):557562. James R, Davies R, Collin J. Functional popliteal artery entrapment is physiological in athletes. British Journal of Surgery 2004; 91:108.

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05: Children
Mercuri E, Lampe A, Straub V, Yuva Y, Longman C, Wright M et al. Congenital muscular dystrophy with short stature, proximal contractures and distal laxity. Neuropediatrics 2004; 35(4):224-229. Isaac S, Athanasou NA, Pike M, Burge PD. Radial nerve palsy owing to localized hypertrophic neuropathy (intraneural perineurioma) in early childhood. Journal of Child Neurology 2004;(1):71-75. Head RA, de Goede CGEL, Newton RWN, Walter JH, McShane MA, Brown RM et al. Pyruvate dehydrogenase deficiency presenting as dystonia in childhood. Developmental Medicine and Child Neurology 2004; 46(10):710-712. Fang C, Portess H, Wilson D. Application of ultrasound in the diagnosis and management of paediatric hip conditions. Current Orthopaedics 2004; 18(4):291-303. Bunn HJ, Roberts P, Thomson AH. Noninvasive ventilation for the management of pulmonary hypertension associated with congenital heart disease in children. Pediatr Cardiol 2004; 25(4):357359. Gallagher A, Pike M, Berg S. Beware CSF pressure measured under general anaesthesia. Arch Dis Child 2004; 89(7):691. Gundeti M, Hitchcock R, Teague W. Paediatric urolithiasis in the UK: a BAPU study. BJU Int 2004; 93:77. Orpen NM, Mathievathaniy M, Hitchcock R. Left-sided gastroschisis and pseudoexstrophy: a rare combination of anomalies. Pediatr Surg Int 2004; 20(7):551-552. Ahmed ML, Ong KK, Thomson AH, Dunger DB. Reduced gains in fat and fat-free mass, and elevated leptin levels in children and adolescents with cystic fibrosis. Acta Paediatr 2004; 93(9):11851191. Brueggemann AB, Peto-Timothy EA, Crook DW, Butler JC, Kristinsson KG, Spratt BG. Temporal and geographic stability of the serogroup-specific invasive disease potential of Streptococcus pneumoniae in children. J Infect Dis 2004; 190(7):1203-1211. English M, Esamai F, Wasunna A, Were F, Ogutu B, Wamae A et al. Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in Kenya. Lancet 2004; 363(9425):19481953. English M, Ngama M, Mwalekwa L, Peshu N. Signs of illness in Kenyan infants aged less than 60 days. Bull World Health Organ 2004; 82(5):323-329. Roberts J, Hunter L, Gravel J, Rosenfeld R, Berman S, Haggard M et al. Otitis media, hearing loss, and language learning: Controversies and current research. J Dev Behav Pediatr 2004; 25(2):110122. Stewart-Brown S, Patterson J, Mockford C, Barlow J, Klimes I, Pyper C. Impact of a general practice based group parenting programme: quantitative and qualitative results from a controlled trial at 12 months. Arch Dis Child 2004; 89(6):519-525. McVernon J, Morgan P, Mallaghan C, Biswas T, Natarajan M, Griffiths D et al. Outbreak of Haemophilus influenzae type b disease among fully vaccinated children in a day-care center. Pediatr Infect Dis J 2004; 23(1):38-41. Hambleton S, Berendt AR. Bone and joint infections in children. Adv Exp Med Biol 2004; 549:47-62.

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Burnett CA, Juszczak E, Sullivan PB. Nurse management of intractable functional constipation: a randomised controlled trial. Arch Dis Child 2004; 89(8):717-722. Fazel M, Stein A. UK immigration law disregards the best interests of children. Lancet 2004; 363(9423):1749-1750. Lucey JF, Rowan CA, Shiono P, Wilkinson AR, Kilpatrick S, Payne NR et al. Fetal infants: The fate of 4172 infants with birth weights of 401 to 500 grams - The Vermont Oxford Network Experience (1996-2000). Pediatrics 2004; 113(6):1559-1566. Sleigh G, Brocklehurst P. Gastrostomy feeding in cerebral palsy: a systematic review. Arch Dis Child 2004; 89(6):534-539. Wiggs L, Stores G. Sleep patterns in children with autistic spectrum disorders (ASD). J Intellect Disabil Res 2004; 48:351. Wiggs L, Stores G. Sleep patterns and sleep disorders in children with autistic spectrum disorders: insights using parent report and actigraphy. Dev Med Child Neurol 2004; 46(6):372-380. Willatt J-MG, Quaghebeur G. Calvarial masses of infants and children. A radiological approach. Clin Radiol 2004; 59(6):474-486. Jiang ZD, Li ZH, Chen C, Wilkinson AR. Possible suboptimal neural function in the auditory brainstem at term in low-risk preterm babies. Pediatr Res 2004; 55(4):2442. Gibson BES, Todd A, Roberts I, Pamphilon D, Rodeck C, Bolton-Maggs P et al. Transfusion guidelines for neonates and older children. Br J Haematol 2004; 124(4):433-453. White J, Shepperd S, Yudkin P, Harnden A, Mant D. Parents measuring pulses; an observational study. Arch Dis Child 2004; 89(3):274-275. Vinh H, Parry C, Hanh V, Chinh M, House D, Tham C et al. Double blind comparison of ibuprofen and paracetamol for adjunctive treatment of uncomplicated typhoid fever. Pediatr Infect Dis J 2004; 23(3):226-230. Grebenik CR, Boyce A, Sinclair ME, Evans RD, Mason DG, Martin B. NICE guidelines for central venous catheterization in children Is the evidence base sufficient? British Journal of Anaesthesia 2004; 92[6], 827-830. Elcioglu NH, Gustavson KH, Wilkie AOM, Yuksel-Apak M, Spranger JW. Recessive omodysplasia: five new cases and review of the literature. Pediatr Radiol 2004; 34(1):75-82. Sullivan PB, Juszczak E, Bachlet A-ME, Thomas AG, Lambert B, Vernon RA et al. Impact of gastrostomy tube feeding on the quality of life of carers of children with cerebral palsy. Dev Med Child Neurol 2004; 46(12):796-800. Burton MJ, Dore CJ. Interventions for recurrent idiopathic epistaxis (nosebleeds) in children. The Cochrane Database of Systematic Reviews 1. 2004.

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06: Diabetes, Endorcrinology and Metabolism

Bastin S, Eaves RJ, Edwards CW, Ichihara O, Whittaker M, Wills M. A soluble-polymer system for the asymmetric transfer hydrogenation of ketones. Journal of Organic Chemistry 2004; 69(16):54055412. Scheuermann-Freestone M, Neubauer S, Clarke K. Effect of chronic peroxisome proliferatoractivated receptor gamma (PPAR gamma) activation on cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes mellitus. Heart 2004; 90(Suppl.2):F. Tan GD, Goossens GH, Humphreys SM, Vidal H, Karpe- Fredrik. Upper and lower body adipose tissue function: a direct comparison of fat mobilization in humans. Obesity Research 2004; 12(1):114118. Ahmad T, Farnie G, Bundred NJ, Anderson NG. The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. Journal of Biological Chemistry 2004; 279(3):1713-1719. Ardilouze JL, Karpe F, Currie JM, Frayn KN, Fielding BA. Subcutaneous adipose tissue blood flow varies between superior and inferior levels of the anterior abdominal wall. International Journal of Obesity 2004; 28(2):228-233. Head RA, Brown RM, Brown GK. Diagnostic difficulties with common SURF1 mutations in patients with cytochrome oxidase-deficient Leigh syndrome. Journal of Inherited Metabolic Disease 2004; 27(1):57-65. Mohanlal N, Holman RR. A standardized triglyceride and carbohydrate challenge: the oral triglyceride tolerance test. Diabetes Care 2004; 27(1):89-94. Ramadan DG, Head RA, Al Tawari A, Habeeb Y, Zaki M, Al Ruqum F et al. Lactic acidosis and developmental delay due to deficiency of E3 binding protein (protein X) of the pyruvate dehydrogenase complex. Journal of Inherited Metabolic Disease 2004; 27(4):477-485. Schafer JRA, Fell DA, Rothman D, Shulman RG. Protein phosphorylation can regulate metabolite concentrations rather than control flux: The example of glycogen synthase. Proceedings of the National Academy of Sciences of the United States of America 2004; 101(6):1485-1490. Cosgrove KE, Straub SG, Barnes PD, Chapman J, Sharp GW, Dunne MJ. Y-26763: ATP-sensitive K(+) channel activation and the inhibition of insulin release from human pancreatic (beta)-cells. Eur J Pharmacol 2004; 486(2):133-139. Murphy NP, Ford-Adams ME, Ong KK, Harris ND, Keane SM, Davies C et al. Prolonged cardiac repolarisation during spontaneous nocturnal hypoglycaemia in children and adolescents with type 1 diabetes. Diabetologia 2004; 47(11):1940-1947. Owen KR, Evans JC, McCarthy MI, Walker M, Hitman GA, Frayling TM et al. Role of the D76N polymorphism of insulin promoter factor-1 in predisposing to Type 2 diabetes. Diabetologia 2004; 47(5):957-958. Clarke PM, Gray AM, Briggs A, Farmer AJ, Fenn P, Stevens RJ, Mathhews, DR, Stratton IM et al. A model to estimate the lifetime health outcomes of patients with type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS no. 68). Diabetologia 2004; 47(10):1747-1759. Desai M, Williams AJK, Horton VA, Bingley PJ, Levy JC, Cull CA et al. GAD65 autoantibody titres at diagnosis in Latent Autoimmune Diabetes in Adults (LADA) differ from Type 1 diabetes (T1D) and together with epitope specificity predict insulin requirement. Diabetologia 2004; 47:509.

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Gardner S, Dunachie SJ, Levy JC. Real gains but practical limitations to glycaemic control with insulin in type 2 diabetes. British Journal of Diabetes and Vascular Disease 2004; 4(2):98-102. Hanefeld M, Brunetti P, Schernthaner GH, Matthews DR, Charbonnel BH. One-year glycemic control with a sulfonylurea plus pioglitazone versus a sulfonylurea plus metformin in patients with type 2 diabetes. Diabetes Care 2004; 27(1):141-147. Hill NR, Matthews DR. Automated retinal image differencing. Diabetologia 2004; 47:1056. Kaisaki PJ, Delpine M, Woon PY, Sebag ML, Wilder SP, Menzel S et al. Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome. Diabetes 2004; 53(7):1900-1904. Levy J. Insulin. British Journal of Diabetes and Vascular Disease 2004; 4(1):5-8. Liew CF, Groves CJ, Wiltshire S, Zeggini E, Frayling TM, Owen KR et al. Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism. Diabetologia 2004; 47(12):2168-2175. Madsbad S, Schmitz O, Ranstam J, Jakobsen G, Matthews DR. Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long- acting glucagon-like peptide 1 analog liraglutide (NN2211) A 12-week, double-blind, randomized, controlled trial. Diabetes Care 2004; 27(6):1335-1342. Mills GW, Avery PJ, McCarthy MI, Hattersley AT, Levy JC, Hitman GA et al. Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to Type 2 diabetes. Diabetologia 2004; 47(4):732-738. Turner HE, Thornton J, V, Wass-John AH. Systematic dose-extension of octreotide LAR: the importance of individual tailoring of treatment in patients with acromegaly. Clin Endocrinol (Oxf) 2004; 61(2):224-231. Wallace TM, Matthews DR. Recent advances in the monitoring and management of diabetic ketoacidosis. QJM 2004; 97(12):773-780. Wallace TM, Levy JC, Matthews DR. An increase in insulin sensitivity and basal beta-cell function in diabetic subjects treated with pioglitazone in a placebo-controlled randomized study. Diabet Med 2004; 21(6):568-576. Wallace TM, Levy JC, Matthews DR. The updated HOMA model: comparison of performance against euglycaemic and hyperglycaemic clamps. Diabetologia 2004; 47:612. Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 2004; 27(6):1487-1495. Wiltshire S, Frayling TM, Groves CJ, Jonathan C, Hitman GA, Sampson M et al. Evidence from a large U.K. family collection that genes influencing age of onset of type 2 diabetes map to chromosome 12p and to the MODY3 /NIDDM2 locus on 12q24. Diabetes 2004; 53(3):855-860. Zeggini E, Parkinson J, Groves CJ, Frayling TM, Hitman GA, Walker M et al. Large-scale association studies of candidate genes and their interactions in Type 2 diabetes. Diabetologia 2004; 47:376. Zeggini E, Parkinson J, Halford S, Katharine R, Frayling TM, Walker M et al. Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset. Diabetes 2004; 53(12):3319-3322. Berendt AR, Lipsky B. Is this bone infected or not? Differentiating neuro-osteoarthropathy from osteomyelitis in the diabetic foot. Current diabetes Reports 2004; 4(6):424-429.

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Durrington PN, Tuomilehto J, Hamann A, Kallend D, Smith K. Rosuvastatin and fenofibrate alone and in combination in type 2 diabetes patients with combined hyperlipidaemia. Diabetes Res Clin Pract 2004; 64(2):137-151. Lipsky BA, Berendt AR, Embil J, de Lalla F. Diagnosing and treating diabetic foot infections. Diabetes-Metabolism Research and Reviews 2004; 20:S56-S64. Crispin M-DM, Ritchie GE, Critchley AJ, Morgan BP, Wilson IA, Dwek RA et al. Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure. FEBS Lett 2004; 566(1-3):270-274. Davis JJ, Wrathmell CL, Zhao J, Fletcher J. The tunnelling conductance of molecularly ordered metalloprotein arrays. J Mol Recognit 2004; 17(3):167-173. Scheuermann-Freestone M, Neubauer S, Clarke K. Effect of chronic peroxisome proliferatoractivated receptor gamma (PPAR gamma) activation on cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes mellitus. Heart 2004; 90:F. Scheuermann FM, Neubauer S, Clarke K. Abnormal cardiac muscle function in heart failure is related to insulin resistance. Cardiovascular Journal of South Africa 2004; 15(4 Suppl 1):s12. Schmidt A, Marescau B, Boehm EA, Renema WKJ, Peco R, Das A et al. Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency. Hum Mol Genet 2004; 13(9):905-921. Thakker RV. Genetics of endocrine and metabolic disorders: parathyroid. Reviews in Endocrine and Metabolic Disorders 2004; 5(1):37-51. Stratton IM, Holman RR, Boulton AJM. Risk factors for neuropathy in UKPDS. Diabetologia 2004; 47:121. Stevens RJ, Coleman RL, Shine BL, Holman RR. Could non-HDL cholesterol replace total/HDL cholesterol ratio to estimate coronary heart disease risk in the UKPDS risk engine? Diabetologia 2004; 47:157. Stevens R, Coleman RL, Adler AI, Stratton IM, Matthews DR, Holman RR. Risk factors for myocardial infarction case fatality and stroke case fatality in type 2 diabetes. Diabetes Care 2004; 27(1):201-207. Matthews DR, Stratton IM, Aldington SJ, Holman RR, Kohner EM. Risks of progression of retinopathy and vision loss related to tight blood pressure control in type 2 diabetes mellitus - UKPDS 69. Arch Ophthalmol 2004; 122(11):1631-1640. Kim JI, Stevens RJ, Holman RR. The haemoglobin glycation index is reproducible in dysglycaemic individual but is not explained by post-challenge plasma glucose levels. Diabetologia 2004; 47:319. Jacoby R. Concomitant loop diuretics and ACE inhibitors increase risk of lithium toxicity in elderly people. Evidence-based mental health 2004; 7(4):120. Holman R, Hines G, Kennedy I, Stevens R, Matthews D, Levy J. A calculator for HOMA. Diabetologia 2004; 47(Suppl.1):610. Evans R, Banks C, Compton R. Amperometric detection of glucose using self-catalytic carbon paste electrodes. Analyst 2004;129[5], 428-431. Cavaco BM, Guerra L, Bradley KJ, Carvalho D, Harding B, Oliveira A et al. Hyperparathyroidism-jaw tumor syndrome in Roma families from Portugal is due to a founder mutation of the HRPT2 gene. J Clin Endocrinol Metab 2004; 89(4):1747-1752.

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Clarke PM, Gray A, Stevens R, Holman R. Cost utility analysis of intensive blood-glucose control, tight blood pressure control and metformin in patients with Type 2 diabetes. Diabetologia 2004; 47(Suppl.1):128. Desai M, Williams AJK, Horton VA, Bingley PJ, Levy JC, Cull CA et al. GAD65 autoantibody titres at diagnosis in Latent Autoimmune Diabetes in Adults (LADA) differ from Type 1 diabetes (T1D) and together with epitope specificity predict insulin requirement. Diabetologia 2004; 47(Suppl.1):509. Ardilouze JL, Fielding BA, Currie JM, Frayn KN, Karpe F. Nitric Oxide and (beta)-Adrenergic Stimulation Are Major Regulators of Preprandial and Postprandial Subcutaneous Adipose Tissue Blood Flow in Humans. Circulation 2004; 109(1):47-52. Cai SJ, Channon KM. Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells. Molecular Therapy 2004; 9:206. Fielding BA, Frayn KN. Lipid metabolism. Curr Opin Lipidol 2004; 15(4):483-485. Fielding BA, Roberts R, Bickerton A, Karpe F, Gilbert M, Frayn KN. Comparison of GC-MS and GCcIRMS for the measurement of [C-13] palmitate enrichment in a stable isotope study in vivo in man. Int J Obes 2004; 28:S165. Frayn KN. Insulin resistance and the concept of metabolic flexibility. Int J Obes 2004; 28:S36. Frayn KN, Fielding BA, Macdonald IA, Coppack SW, Lawrence V, Karpe F. Pulsatile blood flow and lipolysis in human adipose tissue. Int J Obes 2004; 28:S81. Heath RB, Jones R, Frayn KN, Robertson MD. Vagal stimulation exaggerates the inhibitory ghrelin response to oral fat in humans. J Endocrinol 2004; 180(2):273-281. Meininger CJ, Cai S, Parker JL, Channon KM, Kelly KA, Becker EJ et al. GTP cyclohydrolase 1 gene transfer increases nitric oxide synthesis in endothelial cells and isolated vessels from type I and type II diabetic. FASEB J 2004; 18(4):A641. Miller WH, Brosnan MJ, Graham D, Channon KM, Reynolds PN, Baker AH et al. Sustained lowering of systolic blood pressure using an endothelial cell-targeted adenoviral vector. J Hypertens 2004; 22:S15. Miller WH, Brosnan MJ, Graham D, Frater AJ, Channon KM, Danilov SM et al. Targeted delivery of adenovirus expressing eNOS to the endothelium in vivo lowers blood pressure in hypertensive rats. Molecular Therapy 2004; 9:391. Richardson CC, Jones P, Persaud S, Hussain K, Clark A, Christie MR. Sequential expression of elements of beta cell stimulus- secretion coupling follows islet hormone expression in human fetal life. Diabetologia 2004; 47:133. Roberts R, Bickerton A, Fielding BA, Blaak E, Wagenmakers AJM, Gilbert M et al. A new protocol to study fatty acid metabolism in muscle and adipose tissue in subjects with the metabolic syndrome. Int J Obes 2004; 28:S165. Schfer A, Alp NJ, Cai S, Lygate CA, Neubauer- Stefan, Eigenthaler M et al. Reduced vascular NO bioavailability in diabetes increases platelet activation in vivo. Arterioscler Thromb Vasc Biol 2004; 24(9):1720-1726. Trezise A-EO, Farinha CM, Heda GD, Harris A, Amaral MD, Mouchel N. Non-PCR methods for the analysis of CFTR transcripts. Journal of Cystic Fibrosis 2004; 3(SUPPL. 2):25-28. Cull CA, Neil H-AW, Holman RR. Changing aspirin use in patients with Type 2 diabetes in the UKPDS. Diabet Med 2004; 21(12):1368-1371.

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Goldacre MJ, Duncan ME, Cook MP, Neil H-AW. Trends in mortality rates for death-certificate-coded diabetes mellitus in an English population 1979-99. Diabet Med 2004; 21(8):936-939. Neil H-AW, Hammond T, Mant D, Humphries SE. Effect of statin treatment for familial hypercholesterolaemia on life assurance: results of consecutive surveys in 1990 and 2002. Br Med J 2004; 328(7438):500-501. Pooley EC, Fairburn CG, Cooper Z, Sodhi MS, Cowen PJ, Harrison PJ. A 5-HT(2C) Receptor Promoter Polymorphism (HTR2C -759C/T) Is Associated with Obesity in Women, and with Resistance to Weight Loss in Heterozygotes. American Journal of Medical Genetics Neuropsychiatric Genetics 2004; 126 B(1):124-127. Roberts SE, Goldacre MJ, Neil HA. Mortality in young people admitted to hospital for diabetes: database study. Br Med J 2004; 328(7442):741-742. Schultz CJ, Dalton RN, Selwood M, Dunger DB, Neil H-AW. Paternal phenotype is associated with microalbuminuria in young adults with Type 1 diabetes mellitus of short duration. Diabet Med 2004; 21(3):246-251. Siebold C, Hansen BE, Wyer JR, Harlos K, Esnouf RE, Svejgaard A et al. Crystal structure of HLADQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. Proc Natl Acad Sci USA 2004; 101(7):1999-2004.

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07: Renal Tract and Renal Impairment

Abraham L, Hareendran A, Mills IW, Martin ML, Abrams P, Drake MJ et al. Development and validation of a quality-of-life measure for men with nocturia. Urology 2004; 63(3):481-486. Chertow GM, Mason PD, Vaage-Nilsen O, Ahlmen J. On the relative safety of parenteral iron formulations. Nephrology Dialysis Transplantation 2004; 19(6):1571-1575. Karim M, Hill P, Pillai G, Gatter K, Davies DR, Winearls CG. Proliferative glomerulonephritis associated with mantle cell lymphoma - natural history and effect of treatment in 2 cases. Clinical Nephrology 2004; 61(6):422-428. Watson CJ, Firth J, Bradley J, Smith KG, Jamieson NV, Friend PJ et al. Campath 1H (alemtuzumab) in renal transplantation: 5-year comparative follow up. American Journal of Transplantation 2004; 4:900. Koo D-DH, Roberts I-SD, Quiroga I, Procter J, Barnardo M-CNM, Sutton M et al. C4d deposition in early renal allograft protocol biopsies. Transplantation 2004; 78(3):398-403. Mathew T, Kreis H, Friend P. Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: results from five multicenter studies. Clin Transplant 2004; 18(4):446-449. Reddy S, Zilvetti M, Brockmann J, McLaren A, Friend P. Liver transplantation from non-heart-beating donors: current status and future prospects. Liver Transplantation 2004; 10(10):1223-1232. Vaux EC, Taylor DJ, Altmann P, Rajagopalan B, Graham K, Cooper R et al. Effects of carnitine supplementation on muscle metabolism by the use of magnetic resonance spectroscopy and nearinfrared spectroscopy in end-stage renal disease. Nephron Clinical Practice 2004; 97(2):41-48. Watson CJ, Firth J, Bradley J, Smith KG, Jamieson NV, Friend PJ et al. Campath 1H (alemtuzumab) in renal transplantation: 5-year comparative follow up. American Journal of Transplantation 2004; 4(Suppl.8):900. Irish AB, Green FR, Gray DWR. Renal allograft and patient survival in patients with and without a genetic hypercoagulable state who undergo repeat renal transplantation after an initial primary renal allograft thrombosis. American Journal of Transplantation 2004; 4(Suppl.8):1175. rish AB, Green FR, Gray DWR. Inflammation, endothelial dysfunction and inheritance predict prevalent and incident cardiovascular disease in renal transplant recipients: Results of the OxSPIRes cohort. (Oxford study of procoagulant factors in renal transplant recipients). American Journal of Transplantation 2004; 4(Suppl.8):1184. Sester M, Sester U, Clauer P, Heine G, Mack U, Moll T et al. Tuberculin skin testing underestimates a high prevalence of latent tuberculosis infection in hemodialysis patients. Kidney Int 2004; 65(5):18261834. Yamasaki M, Masgrau R, Morgan AJ, Churchill GC, Patel S, Ashcroft-Stephen JH et al. Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells. J Biol Chem 2004; 279(8):7234-7240. Kelly MD, Bandara LR, Lock EA, Kennedy S. Novel biomarkers of nephrotoxicity detected using proteomics. Toxicology 2004; 194(3):208. Klenerman P, Semmo N, Ward S. Cellular immune responses against HCV: T cells take a diversion in the liver. Hepatology 2004; 40(6):1459-1461. Warakaulle DR, Phillips RR, Turner G-DH, Davies D, Protheroe AS. Malignant monotypic epithelioid angiomyolipoma of the kidney. Clin Radiol 2004; 59(9):849-852.

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Thakker R. Dent's disease--a nephrolithiasis disorder associated with defective receptor-mediated endocytosis. Bulletin et mmoires de l'Acadmie royale de mdecine de Belgique 2004; 159(Pt 2):199-211. Shankar VK, Zilvetti M, Handa A, Bowler ICJW, Gray DWR. Chronic diarrhea and weight loss due to Vibrio parahaemolyticus infection in a renal transplant recipient. Transplantation 2004; 78(3):487. Roberts I-SD, Furness PN, Cook HT. Beyond diagnosis: Stage and grade in inflammatory renal disease. Current Diagnostic Pathology 2004; 10(1):22-35. Reddy S, Bhattacharjya S, Maniakin N, Greenwood J, Guerreiro D, Hughes D et al. Preservation of porcine non-heart-beating donor livers by sequential cold storage and warm perfusion. Transplantation 2004; 77(9):1328-1332. Nesbit M, Bowl M, Harding B, Ali A, Ayala A, Crowe C et al. Characterization of GATA3 mutations in the hypoparathyroidism, deafness, and renal dysplasia HDR syndrome. Journal of Biological Chemistry 2004; 279[21], 22624-22634. Jouret F, Igarashi T, Gofflot F, Wilson PD, Karet FE, Thakker RV et al. Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5. Kidney Int 2004; 65(1):198-208. Redman-Christopher WG, Sargent IL. Preeclampsia and the systemic inflammatory response. Semin Nephrol 2004; 24(6):565-570. Stewart GS, Fenton RA, Wang W, Kwon TH, White SJ, Collins VM et al. The basolateral expression of mUT-A3 in the mouse kidney. American Journal of Physiology Renal Physiology 2004; 286(5):F979-F987. Fabre MA, Jones DC, Bunce M, Morris PJ, Peter J, Welsh K, I et al. The impact of thiopurine Smethyltransferase polymorphisms on azathioprine dose 1 year after renal transplantation. Transpl Int 2004; 17(9):531-539. Roberts-Ian SD, Reddy S, Russell C, Davies DR, Friend PJ, Handa A, I et al. Subclinical rejection and borderline changes in early protocol biopsy specimens after renal transplantation. Transplantation 2004; 77(8):1194-1198. Schneemann M, Cathomas R, Laidlaw ST, El Nahas AM, Theakston R-DG, Warrell DA. Lifethreatening envenoming by the Saharan horned viper (Cerastes cerastes) causing micro-angiopathic haemolysis, coagulopathy and acute renal failure: Clinical cases and review. QJM Monthly Journal of the Association of Physicians 2004; 97(11):717-727. Reynard JM. Does anticholinergic medication have a role for men with lower urinary tract symptoms/benign prostatic hyperplasia either alone or in combination with other agents? Current Opinion in Urology 2004; 14(1):13-16. Rochester MA, Brewster SF. Genetics for urologists. BJU International 2004; 94(2):232-237. Warakaulle DR, Prematilleke I, Moore NR. Retroperitoneal fibrosis mimicking retrocrural lymphadenopathy. Clinical Radiology 2004; 59(3):292-293. Zarse CA, McAteer JA, Tann M, Sommer AJ, Kim SC, Paterson RF et al. Helical computed tomography accurately reports urinary stone composition using attenuation values: In vitro verification using high-resolution micro-computed tomography calibrated to Fourier transform infrared microspectroscopy. Urology 2004; 63(5):828-833. Payne SR, Napier-Hemy RD, Ganesan T, Turner WH. Presumptive coding. A preliminary study of the aggregation of input diagnoses to determine their relevance to clinical governance and urological resourcing. BJU International 2004; 93(4):553-557.

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Waldmann H, Cobbold S. Exploiting tolerance processes in transplantation. Science 2004; 305(5681):209-212.

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08: Infection and Immunity

Majumdar S, Kirby A, Berry N, Williams C, Hassan I, Eddleston J et al. An outbreak of imipenemresistant Pseudomonas aeruginosa in an intensive care unit. Journal of Hospital Infection 2004; 58(2):160-161. Ansermino M, Hemsley C. ABC of burns - Intensive care management and control of infection. British Medical Journal 2004; 329(7459):220-223. Evans EH, Kletsas D, Urban J, Menage J, Roberts S. The use of SA-beta-Gal to assess cell senescence in intervertebral disc cells. International Journal of Experimental Pathology 2004; 85(4):A61-A62. Oxenius A, Price DA, Trkola A, Edwards C, Gostick E, Zhang HT et al. Loss of viral control in early HIV-1 infection is temporally associated with sequential escape from CD8(+) T cell responses and decrease in HIV-1-specific CD4(+) and CD8(+) T cell frequencies. Journal of Infectious Diseases 2004; 190(4):713-721. Briggs JAG, Simon MN, Gross I, Krausslich HG, Fuller SD, Vogt VM et al. The stoichiometry of Gag protein in HIV-1. Nature Structural & Molecular Biology 2004; 11(7):672-675. Brown G, Brown R, Head R, Boubriak I, Leonard J, Thomas N. Pyruvate dehydrogenase E1 beta subunit deficiency. Biochimica et Biophysica Acta-Bioenergetics 2004; 1657:11-12. Brown RM, Head RA, Boubriak II, Leonard JV, Thomas NH, Brown GK. Mutations in the gene for the E1 beta subunit: a novel cause of pyruvate dehydrogenase deficiency. Human Genetics 2004; 115(2):123-127. Gordon AC, Lagan AL, Aganna E, Cheung L, Peters CJ, McDermott MF et al. TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study. Genes and Immunity 2004; 5(8):631-640. Herre J, Wiliment JA, Gordon S, Brown GE. The role of dectin-1 in antifungal immunity. Critical Reviews in Immunology 2004; 24(3):193-203. Hobson RP, Munro CA, Bates S, MacCallum DM, Cutler JE, Heinsbroek SEM et al. Loss of cell wall mannosylphosphate in Candida albicans does not influence macrophage recognition. Journal of Biological Chemistry 2004; 279(38):39628-39635. Yang X, Ahmad T, Gogus F, Wallace GR, Madanat W, Kanawati CA et al. Analysis of the CC chemokine receptor 5 (CCR5) Delta32 polymorphism in Behet's disease. European Journal of Immunogenetics 2004; 31(1):11-14. Yang X, Ahmad T, Low J, Jewell DP, Zhang L. Association of epidermal growth factor module containing mucin like hormone receptor 3 (EMR 3) mutation with susceptibility and phenotype of Crohn's disease. Gut 2004; 53:011. Yazdankhah SP, Kriz P, Tzanakaki G, Kremastinou J, Kalmusova J, Musilek M et al. Distribution of serogroups and genotypes among disease- associated and carried isolates of Neisseria meningitidis from the Czech Republic, Greece, and Norway. Journal of Clinical Microbiology 2004; 42(11):51465153. Zhou L, McConville J, Chaudhry V, Adams RN, Skolasky RL, Vincent A et al. Clinical comparison of muscle-specific tyrosine kinase (MuSK) antibody-positive and -negative myasthenic patients. Muscle & Nerve 2004; 30(1):55-60. Abbott RJM, Roversi P, Knott V, Sim RB, Teriete P, McDonnell JM et al. Structural studies of CD55 interactions with human proteins. Mol Immunol 2004; 41(2-3):1.

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Arnold JN, Radcliffe CM, Wormald MR, Royle L, Harvey DJ, Crispin M et al. The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin. J Immunol 2004; 173(11):6831-6840. D'Cruz DP, Mellor PS, Joven B, Sanna G, Allanson J, Taylor J et al. Transverse myelitis as the first manifestation of systemic lupus erythematosus or lupus-like disease: good functional outcome and relevance of antiphospholipid antibodies. J Rheumatol 2004; 31(2):280-285. Ferreira V, Valck C, Sanchez G, Gingras A, Tzima S, Molina MC et al. The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruzi. J Immunol 2004; 172(5):3042-3050. Hickling TP, Clark H, Malhotra R, Sim RB. Collectins and their role in lung immunity. J Leukoc Biol 2004; 75(1):27-33. Kinyanjui SM, Howard T, Williams TN, Bull PC, Newbold CI, Marsh K. The use of cryopreserved mature trophozoites in assessing antibody recognition of variant surface antigens of Plasmodium falciparum-infected erythrocytes. J Immunol Methods 2004; 288(1-2):9-18. Kirby A, Chapman C, Hassan I, Burnie J. The diagnosis of hepatosplenic candidiasis by DNA analysis of tissue biopsy and serum. J Clin Pathol 2004; 57(7):764-765. Kishore U, Gaboriaud C, Waters P, Shrive AK, Greenhough TJ, Reid KBM et al. C1q and tumor necrosis factor superfamily: modularity and versatility. Trends in Immunology 2004; 25(10):551-561. Kojouharova MS, Gadjeva MG, Tsacheva IG, Zlatarova A, Roumenina LT, Tchorbadjieva M, I et al. Mutational Analyses of the Recombinant Globular Regions of Human C1q A, B, and C Chains Suggest an Essential Role for Arginine and Histidine Residues in the C1q-IgG Interaction. J Immunol 2004; 172(7):4351-4358. Larsen F, Madsen HO, Sim RB, Koch C, Garred P. Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein. J Biol Chem 2004; 279(20):21302-21311. Maitland K, Makanga M, Williams TN. Falciparum malaria: current therapeutic challenges. Current Opinion in Infectious Diseases 2004; 17(5):405-412. Mayilyan K, Presanis J, Arnold J, Boyajyan A, Sim R. Measurements of MBL-MASPs complex activities predicts different MBL haplotype compositions in British vs. Armenian populations. Tissue Antigens 2004; 64(4):382. Mayilyan KR, Sim RB, Boyajyan AS, Presanis JS, Soghoyan AF, Dodds AW. Complement C4 isotypes in schizophrenia. Mol Immunol 2004; 41(2-3):159. McConkey SJ, Awi D, Cavenaugh JS, Mendy M, Schneider J, Pearse G et al. Safety, immunogenicity, and efficacy results of a phase II trial of therapeutic vaccines for chronic HBV in the Gambia. Hepatology 2004; 40(4):676A. McShane H. Developing an improved vaccine against tuberculosis. Expert Review of Vaccines 2004; 3(3):299-306. McVernon J, Trotter CL, Slack MPE, Ramsay ME. Trends in Haemophilus influenzae type b infections in adults in England and Wales: surveillance study. Br Med J 2004; 329(7467):655-658. McVernon J, Mitchison NA, Moxon ER. T helper cells and efficacy of Haemophilus influenzae type b conjugate vaccination. Lancet Infectious Diseases 2004; 4(1):40-43. Presanis JS, Arnold JN, Mayilyan K, Gal P, Sim RB. MASP-1 and MASP-2: independent assay and differential inhibition. Mol Immunol 2004; 41(2-3):208.

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Rannan ES, V, Taylor IB, De H, I, Ouweland-Ans MW, Wall SA, Wilkie-Andrew OM. Paternal origin of FGFR3 mutations in Muenke-type craniosynostosis. Hum Genet 2004; 115(3):200-207. Sahyoun C, Floyer LA, Johansen BH, Matthews PM. Towards an understanding of gait control: brain activation during the anticipation, preparation and execution of foot movements. Neuroimage 2004; 21(2):568-575. Smith SM, Jenkinson M, Woolrich MW, Beckmann C, Behrens-Timothy EJ, Johansen BH et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004; 23(Suppl 1):s208-s219. Twigg-Stephen RF, Kan R, Babbs C, Bochukova EG, Robertson SP, Wall SA et al. Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome. Proc Natl Acad Sci USA 2004; 101(23):8652-8657. Vllm BA, de A, I, Cowen PJ, Rolls ET, Kringelbach ML, Smith KA et al. Methamphetamine activates reward circuitry in drug nave human subjects. Neuropsychopharmacology 2004; 29(9):1715-1722. Le Masurier M, Houston G, Cowen P, Grasby P, Sharp- Trevor, Hume S. Tyrosine-free amino acid mixture attenuates amphetamine-induced displacement of (11C)raclopride in striatum in vivo: a rat PET study. Synapse 2004; 51(2):151-157. Vaney C, Vaney S, Wade DT. SaGAS, the Short and Graphic Ability Score: an alternative scoring method for the motor components of the Multiple Sclerosis Functional Composite. Mult Scler 2004; 10(2):231-242. Wade DT, Makela P, Robson P, House H, Bateman- Cynthia. Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Mult Scler 2004; 10(4):434-441. Petkau AJ, White RA, Ebers GC, Reder AT, Sibley WA, Lublin FD et al. Longitudinal analyses of the effects of neutralizing antibodies on interferon beta-1b in relapsing-remitting multiple sclerosis. Mult Scler 2004; 10(2):126-138. Liu X, Tailor J, Wang S, Yianni J, Gregory R, Stein J et al. Reversal of hypertonic co-contraction after bilateral pallidal stimulation in generalised dystonia: a clinical and electromyogram case study. Mov Disord 2004; 19(3):336-340. Maggs FG, Palace J. The pathogenesis of multiple sclerosis: is it really a primary inflammatory process? Mult Scler 2004; 10(3):326-329.

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10: Perinatal Medicine

Waller S, Kurzawinski T, Spitz L, Thakker R, Cranston T, Pearce S et al. Neonatal severe hyperparathyroidism: genotype/phenotype correlation and the use of pamidronate as rescue therapy. European Journal of Pediatrics 2004; 163(10):589-594. Khullar S, Greenwood SL, McCord N, Glazier JD, Ayuk PTY. Nitric oxide and superoxide impair human placental amino acid uptake and increase Na+ permeability: Implications for fetal growth. Free Radical Biology and Medicine 2004; 36(3):271-277. Kurian MA, O'Mahoney ES, Rustin P, Brown G, Treacy EP, King MD. Neonatal seizures and limb malformations associated with liver- specific complex IV respiratory chain deficiency. European Journal of Paediatric Neurology 2004; 8(1):55-59. Brown MA. Mutation of perinatal myosin heavy chain. N Engl J Med 2004; 351(24):2556. Boyd PA, Tondi F, Hicks NR, Chamberlain PF. Autopsy after termination of pregnancy for fetal anomaly: retrospective cohort study. Br Med J 2004; 328(7432):137. Ives NK. Invited commentary to supplement hot topics in neonatology. Acta Paediatr 2004; 93(2):161163. Manning N, Impey L, Lindsell D, Lakhoo K. Prenatally diagnosed portocaval shunt and postnatal outcome: a case report. Prenat Diagn 2004; 24(7):537-540. Patel Y, Boyd PA, Chamberlain P, Lakhoo K. Follow-up of children with isolated fetal echogenic bowel with particular reference to bowel-related symptoms. Prenat Diagn 2004; 24(1):35-37. Schneider JE, Bhattacharya S. Making the mouse embryo transparent: identifying developmental malformations using magnetic resonance imaging. Birth Defects Research Part C 2004; 72(3):241249. Schneider JE, Bse J, Bamforth SD, Gruber AD, Broadbent C, Clarke K et al. Identification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging technique. BMC Developmental Biology 2004; 4(1):16. Gates S, Brocklehurst P, Ayers S, Bowler U. Thromboprophylaxis and pregnancy: Two randomized controlled pilot trials that used low-molecular-weight heparin. Am J Obstet Gynecol 2004; 191(4):1296-1303. Gates S, Brocklehurst P. How should randomised trials including multiple pregnancies be analysed? Br J Obstet Gynaecol 2004; 111(3):213-219. Henderson J, Hockley C, Petrou S, Goldacre M, Davidson L. Economic implications of multiple births: inpatient hospital costs in the first 5 years of life. Arch Dis Child Fetal Neonatal Ed 2004; 89(6):F542-F545. Jiang ZD, Wang J, Brosi DM, Shao XM, Wilkinson AR. One-third of term babies after perinatal hypoxia-ischaemia have transient hearing impairment: dynamic change in hearing threshold during the neonatal period. Acta Paediatr 2004; 93(1):82-87. Jiang ZD, Zhang Z, Wilkinson AR. Frequency-specific hearing impairment in neonates after perinatal hypoxia-ischaemia. Pediatr Res 2004; 56(3):120. Jiang ZD, Brosi DM, Shao XM, Wilkinson AR. Neonates with low Apgar score but without hypoxicischaemic encephalopathy: Sub-optimal brainstem function. Pediatr Res 2004; 56(3):122.

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Jiang ZD, Brosi DM, Wang J, Wilkinson AR. Electrophysiological evidence of prolonged brainstem neuronal damage in term neonates after asphyxia. Pediatr Res 2004; 55(4):2441. Kurinczuk JJ, Gray R, Brocklehurst P. Risk of stillbirth after previous caesarean section. Lancet 2004; 363(9406):402. Rowe RE, Garcia J, Davidson LL. Social and ethnic inequalities in the offer and uptake of prenatal screening and diagnosis in the UK: a systematic review. Public Health 2004; 118(3):117-189. Stoneham MD. I. 'It ain't you do; it's the way that you do it...': Reducing haemodynamic instability during carotid surgery. Br J Anaesth 2004; 92(3):321-323. Burch M, Kaufman L, Archer N, Sullivan I. Persistent pulmonary hypertension late after neonatal aortic valvotomy: a consequence of an expanded surgical cohort. Heart 2004; 90(8):918-920. Kudo Y, Boyd C-AR, Sargent IL, Redman C-WG, Lee JM, Freeman TC. An analysis using DNA microarray of the time course of gene expression during syncytialization of a human placental cell line (BeWo). Placenta 2004; 25(6):479-488. Kudo Y, Boyd CAR. RNA interference-induced reduction in CD98 expression suppresses cell fusion during syncytialization of human placental BeWo cells. FEBS Lett 2004; 577(3):473-477. Kudo Y, Boyd C-AR, Spyropoulou I, Redman C-WG, Takikawa O, Katsuki T et al. Indoleamine 2,3dioxygenase: distribution and function in the developing human placenta. J Reprod Immunol 2004; 61(2):87-98. Wilson C, Nikitenko LL, Sargent IL, Rees-Margaret CP. Adrenomedullin: multiple functions in human pregnancy. Angiogenesis 2004; 7(3):203-212. Goodacre-Tim EE, Hentges F, Moss-Tony LH, Short V, Murray L. Does repairing a cleft lip neonatally have any effect on the longer- term attractiveness of the repair? Cleft Palate Craniofac J 2004; 41(6):603-608.

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11: Urgent and Emergency Care

Bloomer R, Willett K, Pallister I. The stove-in chest: a complex flail chest injury. Injury-International Journal of the Care of the Injured 2004; 35(5):490-493. Harvie P, Gundle R, Willett K. Traumatic periprosthetic acetabular fracture: life threatening haemorrhage and a novel method of acetabular reconstruction. Injury-International Journal of the Care of the Injured 2004; 35(8):819-822. Gerard K, Lattimer V, Turnbull J, Smith H, George S, Brailsford S et al. Reviewing emergency care systems 2: measuring patient preferences using a discrete choice experiment. Emergency Medicine Journal 2004; 21(6):692-697. Banky JP, Turner RJ, Hollowood K. Multiple scrotal epidermolytic acanthomas; secondary to trauma? Clin Exp Dermatol 2004; 29(5):489-491. Goetz P, Blamire A, Rajagopalan B, Cadoux HT, Young D, Styles P. Increase in apparent diffusion coefficient in normal appearing white matter following human traumatic brain injury correlates with injury severity. J Neurotrauma 2004; 21(6):645-654. Wyllie DH, Bowler ICJ, Peto TEA. Relation between lymphopenia and bacteraemia in UK adults with medical emergencies. J Clin Pathol 2004; 57(9):950-955. Martin B, Butler J. Best evidence topic report Two thumb compared with two finger cardiopulmonary resuscitation in infants. Emergency medicine journal 2004; 21(6):711-713. Martin BW. Radiology in paediatric cervical spine injury. Emergency medicine journal 2004; 21(5):648. Black JJM, Ward ME, Lockey DJ. Appropriate use of helicopters to transport trauma patients from incident scene to hospital in the United Kingdom: an algorithm. Emergency medicine journal 2004; 21(3):355-361. Ameratunga SN, Norton RN, Bennett DA, Jackson RT. Risk of disability due to car crashes: a review of the literature and methodological issues. Injury-International Journal of the Care of the Injured 2004; 35(11):1116-1127. Jackson R. Hypertonic or isotonic saline in hypotensive patients with severe head injury. Emergency Medicine Journal 2004; 21(1):80-81. Whitlock G, Norton R, Clark T, Jackson R, MacMahon S. Motor vehicle driver injury and marital status: a cohort study with prospective and retrospective driver injuries. Inj Prev 2004; 10(1):33-36. Dunning J, Daly JP, Malhotra R, Stratford SP, Lomas JP, Lecky F et al. The implications of NICE guidelines on the management of children presenting with head injury. Arch Dis Child 2004; 89(8):763-767.

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12: Respiratory Medicine

Schultz MJ, Millo J, Levi M, Hack CE, Weverling GJ, Garrard CS et al. Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia. Thorax 2004; 59(2):130-135. Aziz ZA, Wells AU, Hansell DM, Bain GA, Copley SJ, Desai SR et al. HRCT diagnosis of diffuse parenchymal lung disease: interobserver variation. Thorax 2004; 59(6):506-511. Evans AL, Gleeson FV. Radiology in pleural disease: State of the art. Respirology 2004; 9(3):300312. Goetghebuer T, Isles K, Moore C, Thomson A, Kwiatkowski D, Hull J. Genetic predisposition to wheeze following respiratory syncytial virus bronchiolitis. Clinical and Experimental Allergy 2004; 34(5):801-803. Goetghebuer T, Kwiatkowski D, Thomson A, Hull J. Familial susceptibility to severe respiratory infection in early life. Pediatric Pulmonology 2004; 38(4):321-328. Scarsbrook A, Gleeson FV. Progress through sound and vision. Respiration 2004; 71(5):448-449. Matsas RA, Thomson AH. New asthma guidelines. Current Paediatrics 2004; 14(4):329-335. McLachlan G, Griesenbach U, Owaki T, Hillery L, Williams J, Zhu YF et al. Recombinant Sendai virus vector to evaluate vector distribution in a large animal model of lung gene transfer. Molecular Therapy 2004; 9(Suppl.1):496. Cardy CM, Maskell NA, Handford PA, Arnold AG, Davies RJO, Morrison PJ et al. Familial spontaneous pneumothorax and FBN1 mutations. Am J Respir Crit Care Med 2004; 169(11):12601262. Chapman SJ, Davies R-JO. The management of pleural space infections. Respirology 2004; 9(1):411. Chapman SJ, Davies-Robert JO. Recent advances in parapneumonic effusion and empyema. Curr Opin Pulm Med 2004; 10(4):299-304. Chapman SJ, Davies-Robert JO. Pleural effusions. Clinical Medicine 2004; 4(3):207-210. Maskell NA, Gleeson F, V, Darby M, Davies-Robert JO. Diagnostically significant variations in pleural fluid pH in loculated parapneumonic effusions. Chest 2004; 126(6):2022-2024. Maskell NA, Lee Y-CG, Gleeson F, V, Hedley EL, Pengelly G, Davies-Robert JO. Randomized trials describing lung inflammation after pleurodesis with talc of varying particle size. Am J Respir Crit Care Med 2004; 170(4):377-382. Millo JL, Schultz MJ, Williams C, Weverling GJ, Ringrose T, Mackinlay CI et al. Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia. Intensive Care Med 2004; 30(1):68-74. Robinson GV, Stradling JR, Davies RJO, Roberts ISD. Post mortem diagnosis of fatal obstructive sleep apnoea. Histopathology 2004; 45(5):542-544. Robinson G. Casebook: chest infection in adults. Practitioner 2004; 248(1657):223-224. West SD, Davies-Robert JO, Lee Y-CG. Pleurodesis for malignant pleural effusions: current controversies and variations in practices. Curr Opin Pulm Med 2004; 10(4):305-310.

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Stradling J. Con: Sleep apnea does not cause cardiovascular disease. Am J Respir Crit Care Med 2004; 169(2):148-149. Stradling JR, Hardinge M, Smith DM. A novel, simplified approach to starting nasal CPAP therapy in OSA. Respir Med 2004; 98(2):155-158. Stradling JR, Hardinge M, Paxton J, Smith DM. Relative accuracy of algorithm-based prescription of nasal CPAP in OSA. Respir Med 2004; 98(2):152-154. Stradling JR, Davies R-JO. Sleep. 1: Obstructive sleep apnoea/hypopnoea syndrome: definitions, epidemiology, and natural history. Thorax 2004; 59(1):73-78. Stradling JR. Reducing the cost of treating obstructive sleep apnea: Good news for patients. Am J Respir Crit Care Med 2004; 170(11):1143-1144. Richeldi L, Ewer K, Losi M, Hansell DM, Roversi P, Fabbri LM et al. Early diagnosis of subclinical multi drug-resistant tuberculosis. Ann Intern Med 2004; 140(9):709-713. Richeldi L, Ewer K, Losi M, Bergamini BM, Roversi- Pietro, Deeks J et al. T cell-based tracking of multidrug resistant tuberculosis infection after brief exposure. Am J Respir Crit Care Med 2004; 170(3):288-295. Westby M, Benson M, Gibson P. Anticholinergic agents for chronic asthma in adults. The Cochrane Database of Systematic Reviews 3. 2004. Chinnery PF, DiMauro S, Shanske S, Schon EA, Zeviani M, Mariotti C et al. Risk of developing a mitochondrial DNA deletion disorder. Lancet 2004; 364(9434):592-596. Colasanti RL, Morris MJ, Madgwick RG, Sutton L, Williams EM. Analysis of tidal breathing profiles in cystic fibrosis and COPD. Chest 2004; 125(3):901-908. Price DB, Honeybourne D, Little P, Mayon-White RT, Read RC, Thomas M et al. Communityacquired pneumonia mortality: a potential link to antibiotic prescribing trends in general practice. Respir Med 2004; 98(1):17-24. Morris MJ, Williams-E-Mark, Madgwick R, Banerjee- Rajarshi, Phillips E. Changes in lung function and tidal airflow patterns after increasing extrathoracic airway resistance. Respirology 2004; 9(4):474480. Awomoyi AA, Nejentsev S, Richardson A, Hull J, Koch O, Podinovskaia M et al. No association between interferon-gamma receptor-1 gene polymorphism and pulmonary tuberculosis in a Gambian population sample. Thorax 2004; 59(4):291-294. Hull J, Rowlands K, Lockhart E, Sharland M, Moore- Catrin, Hanchard N et al. Haplotype mapping of the bronchiolitis susceptibility locus near IL8. Hum Genet 2004; 114(3):272-279. Nicholson AG, Addis BJ, Bharucha H, Clelland CA, Corrin B, Gibbs AR et al. Inter-observer variation between pathologists in diffuse parenchymal lung disease. Thorax 2004; 59(6):500-505. Marfin AG, Pandit JJ, Dombrovskis A, Popat MT, Mihm F. Tracheal tube impingement during nasotracheal fibreoptic intubation. Anaesthesia 2004; 59(10):1043. Henderson JJ, Popat MT, Latto IP, Pearce AC. Difficult Airway Society guidelines for management of the unanticipated difficult intubation. Anaesthesia 2004; 59(7):675-694. Bokhari A, Benham SW, Popat MT. Management of unanticipated difficult intubation: a survey of current practice in the Oxford region. Eur J Anaesthesiol 2004; 21(2):123-127.

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Asai T, Marfin AG, Thompson J, Popat M, Shingu K. Ease of insertion of the laryngeal tube during manual-in-line neck stabilisation. Anaesthesia 2004; 59(12):1163-1166. Shepperd S, Perera R, Bates S, Jenkinson C, Hood K, Harnden A et al. A children's acute respiratory illness scale CARIFS predicted functional severity and family burden. J Clin Epidemiol 2004; 57(8):809-814. Bornman L, Campbell SJ, Fielding K, Bah B, Sillah J, Gustafson P et al. Vitamin D receptor polymorphisms and susceptibility to tuberculosis in West Africa: a case-control and family study. J Infect Dis 2004; 190(9):1631-1641. Cookson W, Moffatt M. Making sense of asthma genes. N Engl J Med 2004; 351(17):1794-1796. Cookson W. The immunogenetics of asthma and eczema: a new focus on the epithelium. Nature Reviews Immunology 2004; 4(12):978-988. Johnstone-Elaine, Brown-Karen, Saunders-Cas, Roberts-Kate, Drury-Mark, Walton-Robert et al. Level of nicotine replacement during a quit-smoking attempt. Nicotine and Tobacco Research 2004; 6(2):377-379. Johnstone EC, Yudkin P, Griffiths SE, Fuller A, Murphy M, Walton R. The dopamine D2 receptor C32806T polymorphism (DRD2 Taq1A RFLP) exhibits no association with smoking behaviour in a healthy UK population. Addiction Biology 2004; 9(3-4):221-226. Johnstone E, Hey K, Drury M, Roberts S, Welch S, Walton R et al. Zyban for smoking cessation in a general practice setting: the response to an invitation to make a quit attempt. Addiction Biology 2004; 9(3-4):227-232. Johnstone EC, Yudkin PL, Hey K, Roberts SJ, Welch SJ, Murphy MF et al. Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch. Pharmacogenetics 2004; 14(2):83-90. Thwaites GE, Nguyen DB, Nguyen HD, Hoang TQ, Thi TO, Nguyen-Thi CT et al. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med 2004; 351(17):17411751. Thwaites GE, Caws M, Chau-Tran TH, Dung NT, Campbell J, I, Phu NH et al. Comparison of conventional bacteriology with nucleic acid amplification (amplified mycobacterium direct test) for diagnosis of tuberculous meningitis before and after inception of antituberculosis chemotherapy. J Clin Microbiol 2004; 42(3):996-1002

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13: Womens Health

Ryan L, Hawton K. 10-Minute consultation: Female dyspareunia. British Medical Journal 2004; 328(7452):1357. Chamberlain AJ, Cooper SM, Allen J, Dean D, Baxter KF, Goodfield-Mark JD et al. Paraneoplastic immunobullous disease with an epidermolysis bullosa acquisita phenotype: two cases demonstrating remission with treatment of gynaecological malignancy. Australasian Journal of Dermatology 2004; 45(2):136-139. Banks E, Reeves G, Beral V, Bull D, Crossley B, Simmonds M et al. Influence of personal characteristics of individual women on sensitivity and specificity of mammography in the Million Women Study: cohort study. British Medical Journal 2004; 329(7464):477-479. Banks E, Reeves G, Beral V, Bull D, Crossley B, Simmonds M et al. Impact of use of hormone replacement therapy on false positive recall in the NHS breast screening programme: results from the million women study. British Medical Journal 2004; 328(7451):1291-1292. McCord N, Ayuk PT, Sargent IL, Redman CW, Boyd RA. Increased L-cystine transport in peripheral blood mononuclear cells and oxidative stress in pre-eclampsia. Journal of the Society for Gynecologic Investigation 2004; 11(2):551. Canfell K, Gray W, Snijders P, Murray C, Tipper S, Drinkwater K et al. Factors predicting successful DNA recovery from archival cervical smear samples. Cytopathology 2004; 15(5):276-282. Ali I, Dawber RAJ, Moncrieff G, Wojnarowska F. The relationship between body mass index and hair distribution in postmenopausal women. Br J Dermatol 2004; 151:34. Ali I, Dawber RAJ, Wojnarowska F. The frequency and distribution of scalp, facial and body hair in postmenopausal women: a comparison of subjective and objective hair changes. Br J Dermatol 2004; 151:34. Ali I, Dawber R. Hirsutism: diagnosis and management. Hosp Med 2004; 65(5):293-297. Cooper SM, Kirtschig G, Jeffery K-JM, Wojnarowska F. No association between hepatitis B or C viruses and vulval lichen planus in a UK population. Br J Obstet Gynaecol 2004; 111(3):271-273. Low SJ, Smith KM, Holt EM. Tension free vaginal tape: is the intra-operative cough test necessary? Int Urogynecol J Pelvic Floor Dysfunct 2004; 15(5):328-330. Brookes ST, Donovan JL, Wright M, Jackson S, Abrams P. A scored form of the Bristol Female Lower Urinary Tract Symptoms questionnaire: Data from a randomized controlled trial of surgery for women with stress incontinence. Am J Obstet Gynecol 2004; 191(1):73-82. Hampel C, Artibani W, Pons ME, Haab F, Jackson S, Romero J et al. Understanding the burden of stress urinary incontinence in Europe: A qualitative review of the literature. Eur Urol 2004; 46(1):1527. Olagundoye V, Jackson S, Manek S. Fatal septicaemia following rupture of a gangrenous fibroid. Br J Obstet Gynaecol 2004; 24(5):534-538. Price N, Jackson SR. Clinical audit of the use of tension-free vaginal tape as a surgical treatment for urinary stress incontinence, set against NICE guidelines. J Obstet Gynaecol 2004; 24(5):534-538. Zaki MM, Pandit M, Jackson S. National survey for intrapartum and postpartum bladder care: assessing the need for guidelines. Br J Obstet Gynaecol 2004; 111(8):874-876.

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Asghar T, Yoshida S, Kennedy S, Negoro K, Zhuo W, Hamana S et al. The tumor necrosis factoralpha promoter-1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population. Hum Reprod 2004; 19(11):2509-2514. Kennedy S. Women's health biobank in India. Indian J Med Res 2004; 120(3):131-132. Kenyon S, Brocklehurst P, Blackburn A, Taylor DJ. Antenatal screening and intrapartum management of Group B Streptococcus in the UK. Bjog-An International Journal of Obstetrics and Gynaecology 2004; 111(3):226-230. Omori S, Yoshida S, Kennedy SH, Negoro K, Hamana S, Barlow DH et al. Polymorphism at codon 72 of the p53 gene is not associated with endometriosis in a Japanese population. J Soc Gynecol Investig 2004; 11(4):232-236. Story L, Kennedy S. Animal studies in endometriosis: a review. ILAR Journal 2004; 45(2):132-138. Wang Z, Yoshida S, Negoro K, Kennedy S, Barlow D, Maruo T. Polymorphisms in the estrogen receptor beta gene but not estrogen receptor alpha gene affect the risk of developing endometriosis in a Japanese population. Fertil Steril 2004; 81(6):1650-1656. Zondervan KT, Weeks DE, Colman R, Cardon LR, Hadfield R, Schleffler J et al. Familial aggregation of endometriosis in a large pedigree of rhesus macaques. Hum Reprod 2004; 19(2):448-455. Olagundoye V, Jackson S, Manek S. Fatal septicaemia following rupture of a gangrenous fibroid. Br J Obstet Gynaecol 2004; 111(10):1141-1142. MacKenzie I, Naish C, Rees M, Manek S. 1170 consecutive hysterectomies: indications and pathology. Journal of the British Menopause Society 2004; 10(3):108-112. MacKenzie I, Bichler J, Mason G, Lunan C, Stewart P, Al A et al. Efficacy and safety of a new, chromatographically purified rhesus D immunoglobulin. Eur J Obstet Gynecol Reprod Biol 2004; 117(2):154-161. MacKenzie IZ. Management of traumatic complications during gynaecological surgery. Current Obstetrics and Gynaecology 2004; 14(1):52-61. Ayuk PT, Dudley S, McShane H, Rees M, MacKenzie IZ. Efficacy of follow-up and contact tracing of women who test positive for genital tract Chlamydia trachomatis prior to pregnancy termination. J Obstet Gynaecol 2004; 24(6):687-689. Edwards JE, Moore RA, McQuay HJ. Rofecoxib for dysmenorrhoea: Meta-analysis using individual patient data. BMC Women's Health 2004; 4(1):5. Goswami D, Tannetta DS, Magee LA, Fuchisawa A, Redman CWG, Sargent IL et al. Excess syncytiotrophoblast microparticle shedding is a feature of pre-eclampsia, but not normotensive intrauterine growth restriction. J Soc Gynecol Investig 2004; 11(2):343. Goulis DG, Walker IAL, de Swiet M, Redman CWG, Williamson C. Preeclampsia with abnormal liver function tests is associated with cholestasis in a subgroup of cases. Hypertension in Pregnancy 2004; 23(1):19-27. Jones G, Jenkinson C, Kennedy S. The impact of endometriosis upon quality of life: a qualitative analysis. J Psychosom Obstet Gynaecol 2004; 25(2):123-133. Jones G, Jenkinson C, Kennedy S. Evaluating the responsiveness of the Endometriosis Health Profile Questionnaire: the EHP-30. Qual Life Res 2004; 13(3):705-713. Jones G, Jenkinson C, Kennedy S. Development of the Short Form Endometriosis Health Profile Questionnaire: the EHP-5. Qual Life Res 2004; 13(3):695-704.

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Muttukrishna S, Tannetta D, Groome N, Sargent I. Activin and follistatin in female reproduction. Mol Cell Endocrinol 2004; 225(1-2):45-56. Fairhurst K, Ziebland S, Wyke S, Seaman P, Glasier A. Emergency contraception: why can't you give it away? - Qualitative findings from an evaluation of advance provision of emergency contraception. Contraception 2004; 70(1):25-29. Glasier A, Fairhurst K, Wyke S, Ziebland S, Seaman P, Walker J et al. Advanced provision of emergency contraception does not reduce abortion rates. Contraception 2004; 69(5):361-366.

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14: Haematological Sciences

Harrison P, Segal H, Furtado C, Verjee S, Sukhu K, Murphy M. Defective high shear platelet function among platelet donors. British Journal of Haematology 2004; 125:212. Llewelyn CA, Williamson LM, Murphy ME, Todd AAM, Taylor R. Leukoreduction and postoperative infections. Transfusion 2004; 44(11):1675-1676. Llewelyn CA, Taylor RS, Todd AAM, Stevens W, Murphy MF, Williamson LM. The effect of universal leukoreduction on postoperative infections and length of hospital stay in elective orthopedic and cardiac surgery. Transfusion 2004; 44(4):489-500. Murphy MF, Kay J-DS. Patient identification: problems and potential solutions. Vox Sanguinis 2004; 87(Suppl.2):197-202. Norton A, Kerr JP, O'Donovan S, Edmondson S, Cheesley P, Stear M et al. Variability in platelet dose and incremental response in haematology patients in the UK. British Journal of Haematology 2004; 125:207. Saito S, Nishinaka T, Westaby S. Hemodynamics of chronic nonpulsatile flow: Implications for LVAD development. Surgical Clinics of North America 2004; 84(1):61-74. Segal HC, Briggs C, Harrison P, Kunka S, Machin SJ, Murphy MF. A large multi-centre evaluation of the methodologies for the accurate platelet counting of severe thrombocytopenia. British Journal of Haematology 2004; 125:106. Stanworth SJ, Hyde C, Heddle N, Rebulla P, Brunskill S, Murphy MF. Prophylactic platelet transfusion for haemorrhage after chemotherapy and stem cell transplantation. The Cochrane Database of Systematic Reviews [4], 2004. Diniz SN, Nomizo R, Cisalpino PS, Teixeira MM, Brown GD, Mantovani A et al. PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophages. Journal of Leukocyte Biology 2004; 75(4):649-656. Knowles HJ, Tian YM, Mole DR, Harris AL. Novel mechanism of action for hydralazine - Induction of hypoxia-inducible factor-1 alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases. Circulation Research 2004; 95(2):162-169. Marshall ASJ, Willment JA, Lin HH, Williams DL, Gordon S, Brown GD. Identification and characterization of a novel human Myeloid inhibitory c-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes. Journal of Biological Chemistry 2004; 279(15):14792-14802. Reid DM, Montoya M, Taylor PR, Borrow P, Gordon S, Brown GD et al. Expression of the betaglucan receptor, dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions. Journal of Leukocyte Biology 2004; 76(1):86-94. Anguita E, Hughes J, Heyworth C, Blobel GA, Wood WG, Higgs DR. Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2. EMBO J 2004; 23(14):2841-2852. Armesilla AL, Williams JC, Buch MH, Pickard A, Emerson M, Cartwright EJ et al. Novel functional interaction between the plasma membrane Ca(2+) pump 4b and the proapoptotic tumor suppressor Ras-associated factor 1 (RASSF1). J Biol Chem 2004; 279(30):31318-31328. Arnold JN, Radcliffe CM, Royle L, Dwek RA, Rudd PM, Sim RB. Immunoglobulin glycosylation: the search for MBL binding targets. Mol Immunol 2004; 41(2-3):6.

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Kluin-Nelemans HC, Buck G, le Cessie S, Richards S, Beverloo HB, Falkenburg JHF et al. Randomized comparison of low-dose versus high-dose interferon- alfa in chronic myeloid leukemia: prospective collaboration of 3 joint trials by the MRC and HOVON groups. Blood 2004; 103(12):44084415. Ryan TJ. Lymphatic filariasis and the International Society of Lymphology. Lymphology 2004; 37(3):151-157. Ryan TJ. A search for consensus on the staging of lymphedema. Lymphology 2004; 37(4):180-181. Ryan T. The ageing of the blood supply and the lymphatic drainage of the skin. Micron 2004; 35(3):161-171. Sim RB, Tsiftsoglou SA. Proteases of the complement system. Biochem Soc Trans 2004; 32(1):2127. Baker PM, Davidson SR, Keeling DM. The combined use of D-dimers and diagnostic imaging in the exclusion of deep vein thrombosis in a nurse led outpatient service. Br J Haematol 2004; 125:144. Brown SA, Williams MD, Keeling DM, Yee TT, Collis PW, Dasani H et al. Low incidence of high titre FVIII inhibitors in previously untreated children with severe haemophilia A treated only with intermediate FVIII concentrate (BPL 8Y). Experience from five comprehensive care centres in the UK. Br J Haematol 2004; 125:136. Giangrande-Paul LF. Blood products for hemophilia: past, present and future. BioDrugs 2004; 18(4):225-234. Giangrande P-LF. Gene therapy for hemophilia? No. Journal of Thrombosis and Haemostasis 2004; 2(8):1236-1237. Keeling DM, Mackie IJ, Moody A, Watson HG. The diagnosis of deep vein thrombosis in symptomatic outpatients and the potential for clinical assessment and D-dimer assays to reduce the need for diagnostic imaging. Br J Haematol 2004; 124(1):15-25. Laffan M, Brown SA, Collins PW, Cumming AM, Hill FGH, Keeling D et al. The diagnosis of von Willebrand disease: A guideline from the UK Haemophilia Centre Doctors' Organization. Haemophilia 2004; 10(3):199-217. Villar A, Aronis S, Morfini M, Santagostino E, Auerswald G, Thomsen HF et al. Pharmacokinetics of activated recombinant coagulation factor VII (Novo Seven) in children vs. adults with haemophilia A. Haemophilia 2004; 10(4):352-359. Ahmed M, Sternberg A, Hall G, Thomas A, Smith- Owen, O'Marcaigh A et al. Natural history of GATA1 mutations in Down syndrome. Blood 2004; 103(7):2480-2489. Chotivanich K, Sritabal J, Udomsangpetch R, Newton P, Stepniewska KA, Ruangveerayuth R et al. Platelet-induced autoagglutination of Plasmodium falciparum- infected red blood cells and disease severity in Thailand. J Infect Dis 2004; 189(6):1052-1055. Fisher C, Steensma D, Janmohamed R, Kaczmarski R, Reilly JT, Vyas P. Absence of mutations in the key megakaryocyte transcriptional regulator FOG-1 in patients with idiopathic myelofibrosis. Br J Haematol 2004; 126(5):750-752. Guyot B, Valverde G, V, Porcher C, Vyas- Paresh. Deletion of the major GATA1 enhancer HS 1 does not affect eosinophil GATA1 expression and eosinophil differentiation. Blood 2004; 104(1):89-91. O'Shaughnessy DF, Atterbury C, Maggs PB, Murphy M, Thomas D, Yates S et al. Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. Br J Haematol 2004; 126(1):11-28.

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Saddick D, McNally EG, Richardson M. MRI of Hoffa's fat pad. Skeletal Radiol 2004; 33(8):433-444. Schlaeger TM, Schuh A, Flitter S, Fisher A, Mikkola H, Orkin SH et al. Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1. Mol Cell Biol 2004; 24(17):7491-7502. Malladi R, Peniket A, Collins G, Littlewood T. Fludarabine-melphalan reduced-intensity conditioning matched sibling bone marrow stem cell transplantation is an effective treatment for myeloid disorders. Bone Marrow Transplant 2004; 33:S116. Valverde G, V, Guyot B, Anguita E, Hamlett I, Porcher C, Vyas P. Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for ciselement identification. Blood 2004; 104(10):3106-3116. Di Giorgio M, Edwards AA, Moquet JE, Finnon P, Hone PA, Lloyd DC et al. Chromosome aberrations induced in human lymphocytes by heavy charged particles in track segment mode. Radiation Protection Dosimetry 2004; 108(1):47-53. Lindholm C, Edwards A. Long-term persistence of translocations in stable lymphocytes from victims of a radiological accident. Int J Radiat Biol 2004; 80(8):559-566. Livesey KJ, Wimhurst V-LC, Carter K, Worwood M, Cadet E, Rochette J et al. The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading. J Med Genet 2004; 41(1):6-10. Lloyd D, Hone P, Edwards A, Cox R, Halls J. The repair of gamma-ray-induced chromosomal damage in human lymphocytes after exposure to extremely low frequency electromagnetic fields. Cytogenetic and Genome Research 2004; 104(1-4):188-192. Schfer A, Wiesmann F, Neubauer S, Eigenthaler M, Bauersachs J, Channon KM. Rapid regulation of platelet activation in vivo by nitric oxide. Circulation 2004; 109(15):1819-1822. Steensma DP, Higgs DR, Fisher CA, Gibbons RJ. Acquired somatic ATRX mutations in myelodysplastic syndrome associated with alpha thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations. Blood 2004; 103(6):2019-2026. Watkins F, Fidler C, Boultwood J, Wainscoat JS. Adherence to deferoxamine therapy: Heeding hippocrates and osler. Am J Hematol 2004; 76(4):417. Marafioti T, Pozzobon M, Hansmann ML, Delsol- Georges, Pileri SA, Mason DY. Expression of intracellular signaling molecules in classical and lymphocyte predominance Hodgkin disease. Blood 2004; 103(1):188-193. Shankar VK, Chaudhury-S-Ray, Uthappa MC, Handa A, Hands LJ. Changes in blood coagulability as it traverses the ischemic limb. J Vasc Surg 2004; 39(5):1033-1042. Zhang J, Pellagatti A, Campbell L, Eagleton H, Gal S, Fidler C et al. Neutrophil PRV-1 gene expression in myeloproliferative, myelodysplastic and reactive blood disorders. Br J Haematol 2004; 125:53. Viprakasit V, Tanphaichitr VS, Veerakul G, Chinchang W, Petrarat S, Pung AP et al. Co-inheritance of Hb Pak Num Po, a Novel (alpha)1 Gene Mutation, and (alpha)(0) Thalassemia Associated with Transfusion-Dependent Hb H Disease. Am J Hematol 2004; 75(3):157-163. Viprakasit V, Tanphaichitr VS, Chinchang W, Sangkla P, Weiss MJ, Higgs DR. Evaluation of alpha hemoglobin stabilizing protein (AHSP) as a genetic modifier in patients with beta thalassemia. Blood 2004; 103(9):3296-3299.

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Steensma DP, Viprakasit V, Hendrick A, Goff DK, Leach J, Gibbons RJ et al. Deletion of the (alpha)globin gene cluster as a cause of acquired (alpha)-thalassemia in myelodysplastic syndrome. Blood 2004; 103(4):1518-1520. Masir N, Jones M, Pozzobon M, Marafioti T, Volkova O, Mechetina L, V et al. Expression pattern of FCRL FREB, FcRX in normal and neoplastic human B cells. Br J Haematol 2004; 127(3):335-343. Marafioti T, Mancini C, Ascani S, Sabattini E, Zinzani P, Pozzobon M et al. Leukocyte-specific phosphoprotein-1 and PU1: two useful markers for distinguishing T-cell-rich B-cell lymphoma from lymphocyte-predominant Hodgkin's disease. Haematologica 2004; 89(8):957-964. Gellrich S, Wernicke M, Wilks A, Lukowsky A, Muche JM, Jasch KC et al. The cell infiltrate in lymphomatoid papulosis comprises a mixture of polyclonal large atypical cells (CD30-positive) and smaller monoclonal T cells (CD30-negative). J Invest Dermatol 2004; 122(3):859-861. Fidler C, Watkins F, Bowen DT, Littlewood TJ, Wainscoat JS, Boultwood J. NRAS, FLT3 and TP53 mutations in patients with myelodysplastic syndrome and a del(5q). Haematologica 2004; 89(7):865866. Bokemeyer C, Littlewood T, Aapro M. Is once-weekly epoetin beta 'highly effective' in treating anaemia in patients with lymphoproliferative malignancy? Br J Haematol 2004; 125(1):98-99. Graca L, Le Moine A, Lin CY, Fairchild PJ, Stephen P, Waldmann H. Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells. Proc Natl Acad Sci USA 2004; 101(27):10122-10126. Guzik TJ, Sadowski J, Kapelak B, Jopek A, Rudzinski P, Pillai R et al. Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins. Arterioscler Thromb Vasc Biol 2004; 24(9):1614-1620. Hale G, Rebello P, Brettman LR, Fegan C, Kennedy B, Kimby E et al. Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration. Blood 2004; 104(4):948-955. Harrison P. In vitro measurement of high-shear platelet adhesion and aggregation by the PFA-100. Methods Mol Biol 2004; 272:215-223. Harrison P, Briggs C, Machin SJ. Platelet counting. Methods Mol Biol 2004; 272:29-46. Harrison P. Measuring platelet function? Hematology Journal 2004; 5(Suppl 3):s164-s169. Marshall SJ, Senis YA, Auger JM, Feil R, Hofmann F, Salmon G et al. GPIb-dependent platelet activation is dependent on Src kinases but not MAP kinase or cGMP-dependent kinase. Blood 2004; 103(7):2601-2609. Mccabe DJH, Harrison PS, Sidhu PS, Brown MM, Machin SJ. Circulating reticulated platelets in the early and late phases after ischaemic stroke and transient ischaemic attack. Br J Haematol 2004; 126(6):861-869. Mistry AR, Felix CA, Whitmarsh R, Mason A, Reiter A, Cassinat B et al. Genomic breakpoint cloning and a functional assay of DNA topoisomerase II cleavage reveal translocation mechanism underlying formation of t(15;17) in therapy-related acute promyelocytic leukaemia. Br J Haematol 2004; 125:215. Novitzky N, Thomas V, Stubbings H, Hale G, Waldmann H. Radiotherapy-based conditioning is effective immunosuppression for patients undergoing transplantation with T-cell depleted stem cell grafts for severe aplasia. Cytotherapy 2004; 6(5):450-456. Novitzky N, Thomas V, Hale G, Waldmann H. Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience. Cytotherapy 2004; 6(2):172-181.

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Novitzky N, Thomas V, Hale G, Waldmann H. T-cell depletion of stem cell grafts with campath-1H "in the bag" followed by cyclosporin immunosuppression remains a cost effective strategy in transplantation. Bone Marrow Transplant 2004; 33:S93. Schmitz N, Ljungman P, Cordonnier C, Kempf C, Linkesch W, Alegre A et al. Lenograstim after autologous peripheral blood progenitor cell transplantation: results of a double-blind, randomized trial. Bone Marrow Transplant 2004; 34(11):955-962. Shaw BE, Maldonaldo H, Madrigal JA, Smith C, Petronzelli F, Mayor NP et al. Polymorphisms in the TNFA gene promoter region show evidence of strong linkage disequilibrium with HLA and are associated with delayed neutrophil engraftment in unrelated donor hematopoietic stem cell transplantation. Tissue Antigens 2004; 63(5):401-411. Tso A, Harris L, Littlewood T. Acceptability to a general haematology clinic of written responses to referrals: questionnaire study. Br Med J 2004; 329(7472):946-947. Allen DL, Samol J, Benjamin S, Verjee S, Tusold A, Murphy MF. Survey of the use and clinical effectiveness of HPA-1a/5b-negative platelet concentrates in proven or suspected platelet alloimmunization. Transfus Med 2004; 14(6):409-417. Bolton-Maggs P-HB, Murphy MF. Blood transfusion. Archives of Disease in Childhood 2004; 89(1):47. Clark S, Youngman LD, Chukwurah B, Palmer A, Parish- Sarah, Peto R et al. Effect of temperature and light on the stability of fat-soluble vitamins in whole blood over several days: implications for epidemiological studies. Int J Epidemiol 2004; 33(3):518-525. Dong T, Stewart JG, Chen N, Easterbrook P, Xu X, Papagno L et al. HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. J Exp Med 2004; 2004(12):1547-1557. Feng G, Wood K. Regulatory T cells--an emerging role in transplantation. Yonsei Med J 2004; 45(6):968-977. Harrison P, Segal H, Furtado C, Verjee S, Sukhu- Kampta, Murphy MF. High incidence of defective high-shear platelet function among platelet donors. Transfusion (Paris) 2004; 44(5):764-770. Murphy MF, Kay J-DS. Barcode identification for transfusion safety. Curr Opin Hematol 2004; 11(5):334-338. Murphy MF, Stearn BE, Dzik WH. Current performance of patient sample collection in the UK. Transfus Med 2004; 14(2):113-121. Robson K-JH, Merryweather-Clarke AT, Cadet E, Viprakasit V, Zaahl M, Pointon JJ et al. Recent advances in understanding haemochromatosis: a transition state. J Med Genet 2004; 41(10):721-730. Spriewald BM, Ensminger SM, Jenkins S, Morris P, Wood KJ. Intrathymic delivery of plasmidencoding endoplasmic reticulum signal- sequence-deleted MHC class I alloantigen can induce longterm allograft survival. Transpl Int 2004; 17(8):458-462. Stanworth SJ, Hyde C, Heddle N, Rebulla P, Brunskill S, Murphy MF. Prophylactic platelet transfusion for haemorrhage after chemotherapy and stem cell transplantation. The Cochrane Database of Systematic Reviews 4. 2004. Stanworth SJ, Brunskill SJ, Hyde CJ, McClelland D-BL, Murphy MF. Is fresh frozen plasma clinically effective? A systematic review of randomized controlled trials. Br J Haematol 2004; 126(1):139-152. Wood KJ, Luo S, Akl A. Regulatory T cells: potential in organ transplantation. Transplantation 2004; 77(1 Suppl):s6-s8.

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Weatherall DJ. The Thalassemias: The Role of Molecular Genetics in an Evolving Global Health Problem. Am J Hum Genet 2004; 74(3):385-392. Weatherall DJ. Thalassaemia: the long road from bedside to genome. Nature Reviews Genetics 2004; 5(8):625-631.

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Burge SM, Lancaster T. Assessment in undergraduate dermatology. Clin Exp Dermatol 2004; 29(4):441-446. Burge SM. Learning dermatology. Clin Exp Dermatol 2004; 29(3):337-340. Burge SM. Teaching dermatology. Clin Exp Dermatol 2004; 29(2):206-210. Burge SM. Curriculum planning in dermatology. Clin Exp Dermatol 2004; 29(1):100-104. Clayton TH, Layton A, Clark SM, Wojnarowska F. Pemphigus foliaceus associated with conjunctivitis. Br J Dermatol 2004; 151(1):259-260. Clayton TH, Layton A, Clark S, Wojnarowska F. Childhood pemphigus foliaceus with conjunctivitis. J Am Acad Dermatol 2004; 50(3):507. Coltart I, Lewis G, Taylor D, Burge S. Let there be light! An audit of environmental lighting for clinical examination. Br J Dermatol 2004; 151:47-48. Cooper SM, Gao XH, Powell JJ, Wojnarowska F. Does treatment of vulvar lichen sclerosus influence its prognosis? Arch Dermatol 2004; 140(6):702-706. Han J, Hughes MA, Cherry GW. Effect of glucose concentration on the growth of normal human dermal fibroblasts in vitro. J Wound Care 2004; 13(4):150-153. Hill DP, Poore S, Wilson J, Robson MC, Cherry GW. Initial healing rates of venous ulcers: Are they useful as predictors of healing? Am J Surg 2004; 188(SUPPL. 1):22S-25S. Jaakkola E, Herzberg I, Crane AM, Pointon JJ, Laiho K, Kauppi M et al. A novel human leucocyte antigen-DRB1 genotyping method based on multiplex primer extension reactions. Tissue Antigens 2004; 64(1):88-95. Jia CY, Yang YH, Hughes MA, Cherry GW. The effect of intermittent radiant warming on the contraction of collagen lattices populated with human dermal fibroblasts and on the proliferation of ulcer fibroblasts in monolayer: An in-vitro pilot study. Wounds-A Compendium of Clinical Research and Practice 2004; 16(4):124-133. Xia ZD, Hu D, Wilson JM, Cherry GW, Ryan TJ. How echographic image analysis of venous oedema reveals the benefits of leg elevation. J Wound Care 2004; 13(4):125-128. Giles JW, Sear JW, Fox P. Effect of chronic (beta)-blockade on peri-operative outcome in patients undergoing non-cardiac surgery: An analysis of observational and case control studies. Anaesthesia 2004; 59(6):574-583. Gray D-WR, Sudhakaran N, Titus TT, McShane P, Johnson P. Development of a novel digestion chamber for human and porcine islet isolation. Transplant Proc 2004; 36(4):1135-1138. Sewell JC, Sear JW. Derivation of preliminary three-dimensional pharmacophoric maps for chemically diverse intravenous general anaesthetics. Br J Anaesth 2004; 92(1):45-53. Sewell JC, Sear JW. Derivation of preliminary three-dimensional pharmacophores for nonhalogenated volatile anesthetics. Anesth Analg 2004; 99(3):744-751. Zaugg M, Schaub MC, Foex P. Myocardial injury and its prevention in the perioperative setting. Br J Anaesth 2004; 93(1):21-33.

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Swan M, Gwilym S, Hollowood K, Venning V, Cassell O. Treatment of nevoid hyperkeratosis of the nipple and areola by shave excision. Ann Plast Surg 2004; 53(5):510-512. Millar J. Fast-tracking in day surgery. Is your journey to the recovery room really necessary? Br J Anaesth 2004; 93(6):756-758. Leuwer M, Haeseler G, Hecker H, Bufler J, Dengler R, Aronson JK. An improved model for the binding of lidocaine and structurally related local anaesthetics to fast-inactivated voltage-operated sodium channels, showing evidence of cooperativity. Br J Pharmacol 2004; 141(1):47-54. Corkhill A, Primrose JN, Mant D. Follow up after colorectal surgery (the FACS trial). Br J Cancer 2004; 91:S78. Avivi I, Chakrabarti S, Milligan DW, Waldmann H, Hale G, Osman H et al. Incidence and outcome of Adenovirus disease in transplant recipients after reduced-intensity conditioning with alemtuzumab. Biol Blood Marrow Transplant 2004; 10(3):186-194. Barden J, Edwards J, Moore RA, McQuay HJ. Single dose oral diclofenac for postoperative pain. The Cochrane Database of Systematic Reviews 2. 2004. Barden J, Edwards JE, Mason L, McQuay HJ, Moore R. Outcomes in acute pain trials: systematic review of what was reported? Pain 2004; 109(3):351-356. Barden J, Edwards JE, McQuay HJ, Andrew MR. Pain and analgesic response after third molar extraction and other postsurgical pain. Pain 2004; 107(1-2):86-90. Edwards JE, Moore RA, McQuay HJ. Individual patient meta-analysis of single-dose rofecoxib in postoperative pain. BMC Anesthesiology 2004; 4(1):3. Chambers WM, Mortensen N-JM. Postoperative leakage and abscess formation after colorectal surgery. Best Practice and Research Clinical Gastroenterology 2004; 18(5):865-880. Collin J, Murie J. Uncovering occult operative morbidity and mortality. Br J Surg 2004; 91(3):262-263. Lindsey I, Jones OM, Smilgin-Humphreys MM, Cunningham C, Mortensen NJ. Patterns of fecal incontinence after anal surgery. Dis Colon Rectum 2004; 47(10):1643-1649. Ali I, Moncrieff G, Dawber RA, Wojnarowska F. Universal diffuse hair loss: a novel androgenindependent phenomenon of ageing? Br J Dermatol 2004; 151:33-34. Giehl KA, Ferguson DJP, Dawber RPR, Pittelkow MR, Foehles J, De Berker DAR. Update on detection, morphology and fragility in pili annulati in three kindreds. J Eur Acad Dermatol Venereol 2004; 18(6):654-658. Millard TP, Dhitavat J, Hollowood K, Burge SM. 'Groveroid' Darier's disease? Br J Dermatol 2004; 150(3):600-602. Wong YW, Powell SM, Wawryka HJ. Hand eczema in healthcare workers and the value of a joint occupational health/dermatology clinic. Br J Dermatol 2004; 151:114. Cooper SM, Dhittavat J, Millard P, Burge S. Extensive Grover's-like eruption with lentiginous 'freckling': report of two cases. Br J Dermatol 2004; 150(2):350-352. Winsey S, Lonie L, Allen J, Bunce M, Marshall SE, Wojnarowska F. Genetic variation in COL17A1 and the development of bullous pemphigoid. Exp Dermatol 2004; 13(3):140-147. Black A-PB, Seneviratne SL, Jones L, King AS, Winsey S, Arsecularatne G et al. Rapid effector function of circulating NC16A-specific T cells in individuals with mucous membrane pemphigoid. Br J Dermatol 2004; 151(6):1160-1164

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