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10:19 22:15 44:12 boy 288:15 151:15 195:17 56:15 60:8 62:4
44:15 97:22 102:15 BP 306:13 burial 148:19 139:8,12,19 141:15
102:21 104:4 105:6 Branch 6:6 146:3 burning 154:7 318:6 141:18 143:5,11
106:20 107:2 113:2 168:1 business 57:3 144:10,16,19
113:3 127:17,20 brave 290:13 busy 323:22 145:18,19 146:4
128:2,10 bravely 284:16 buying 315:1,7 148:8 168:2 181:5
BLUMENTHAL break 131:9 303:17 Bye-bye 294:7 181:7,17,19 185:9
104:8 breaking 135:6 B-minus 35:14 36:1 185:21 186:2,8
blunt 298:5 breaks 289:22 38:3 48:6 97:15,21 187:9 252:11
BMC 294:19 breathe 285:19 98:2 293:20 320:9
BMT 276:12 279:9 Brent 9:1 10:19 B-plus 38:4 42:20 cancers 24:8 27:21
board 167:20 22:15 44:11 48:4 156:22 140:17 141:3
Bob 278:1 brief 78:14 89:20 can’t 105:4 117:10
body 141:17 281:21 105:19 131:9,11 C 121:9 132:1 158:9
285:7 185:1 192:8 240:6 c 2:1 11:1 12:1 229:3 158:15 163:17
bone 18:18 24:21 briefing 45:2 174:14 235:5 164:20 249:10
25:2,9,10,11 60:7 174:14 186:9 calcineurin 192:14 257:5 259:14,15
67:18 137:10 150:6 202:11 207:10 192:15,17 193:15 278:3 285:6,14
208:20 216:9 231:2 314:19 296:6 295:19 312:11,12
245:1 259:10 briefly 22:10 59:1 calcium 219:7 316:10 321:20
261:17 270:1 84:19 95:3 156:16 calculate 71:15 327:17 329:4
276:17 278:21 226:7 314:7 315:9 201:12 203:19 cap 133:11
279:1 288:1 293:21 bring 20:21 193:18 calculations 62:14 capacity 146:21
325:18 bringing 331:3 California 14:5 277:15 289:16
bones 25:5 282:20 brings 153:22 181:9 capricious 242:15
292:3 Britain 97:1 call 10:5 11:10 13:3 capsule 197:13 229:4
Bonnie 8:13 10:10,15 British 274:6 180:12 218:3 295:17
18:21 broke 288:19 221:11 240:5 capsules 228:21
bony 67:22 bronchiolitis 221:13 282:10 311:19 293:8 295:22
book 123:3,6 brother 152:7 279:9 called 142:10 180:17 capture 69:13,20
boss 331:22 332:20 281:17 276:11 302:21 72:19 203:14
Boston 5:5 14:15 brought 270:18 caloric 201:13,15 254:18
129:5 280:16 329:14 203:3,16,19 227:13 captured 69:18 72:14
bothered 161:5 330:17 332:18 228:16 229:21 76:10 203:15
172:10 173:7 brown 31:18 235:6 248:13,14 233:22
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carbohydrates 282:3 229:17 249:21 203:18 204:13 253:10 256:22
carcinoma 314:2,9 264:22 298:15 216:12 252:4 257:10 260:22
cardiac 67:19 68:14 caused 54:14 95:22 central 37:4 40:7 261:11 264:12
care 13:9 26:17 150:11 156:14 69:12 95:8 265:7,14 266:8,18
35:15 59:2 75:11 285:16 286:17 certain 163:15 268:7 269:11,14,16
77:17,21 81:7 causes 32:16 212:6,8 165:12 226:17 269:18 274:20
96:19 97:1 98:17 213:11,20,22 223:1 320:18 298:22 299:3,6,10
112:13,13 116:13 causing 87:11 192:4 certainly 97:7 99:10 299:14,17,20 300:2
134:12 139:3 161:4 CBER 144:14 121:3 161:10 300:5,10,19 301:2,4
161:16 166:9,17 CCG 61:21 62:5,11 162:18 165:19 301:8,13,20 302:7
170:5 201:4 225:3 67:4 78:5 85:12 192:22 251:19 302:11,14 303:7,10
230:17 234:16 CDER 1:2 6:16,19,22 271:12 282:17 303:15,19 305:8,12
288:17 311:2 312:6 7:6,9,12,14,19,22 284:6 312:14 317:6 306:17 308:6,14
carefully 26:8 219:5 8:2,5 144:14 certainty 165:15 309:1 310:3 311:12
carried 26:20 29:3 CD4 196:2 272:13 312:9 313:20
69:14 74:18 99:22 CD8 196:2 cetera 268:12 298:9 314:11 316:14
199:5 ceiling 133:7,11 chair 2:5 5:13 24:3 317:14 318:4,11,21
carries 192:2 celebrating 288:15 52:14 184:12 319:4,9,13,16 321:5
cars 282:21 cell 29:22 184:22 chairing 13:6 321:13 322:10
cascade 31:5,7 196:8 216:9 247:2 chairman 23:22 324:5,8 327:5,10
case 37:2 45:11 66:3 276:18 291:7 314:1 32:10 332:12 328:19 329:7,21,21
66:17 69:13 70:21 314:8 chairperson 13:4 330:8 331:14 332:1
70:22 76:10,11,12 cells 31:13,17,17 15:7,10,15 18:11 333:1,4
76:16 77:1,2,5 190:17 192:12 58:2 89:12 98:8,18 challenge 164:10
78:10 90:21 91:13 208:21,22 216:10 99:5 102:8 105:18 challenged 28:6
91:17 92:3 94:15 228:7 231:1 244:18 106:9,18 107:4,12 challenges 22:17
94:17,18 95:12,13 259:10 109:5,9 112:16 52:4
118:7,9,10 122:1,7 center 1:2 3:10,12,13 115:11 116:3 chance 48:7 110:21
122:15,17 142:14 3:17,22 4:6,13,16 117:11 123:15,22 111:4 139:22
143:19 144:11 4:21 5:9 6:7 8:22 124:6 126:15 131:7 152:17 153:7
158:6 160:15 9:5 13:14 14:3,13 133:13 134:18 162:11 259:18
172:12 175:18 16:10 22:12,20 135:2,11 141:19 chances 28:13
221:8,9 242:14 32:12 52:13 144:6 153:17 154:10 change 25:17 26:7
262:8 265:18 145:19 181:7,17 155:22 156:2,5 27:18 56:13 77:6,7
cases 60:9 71:11,13 182:22 185:9,21 157:2 160:4,21 100:13,16 124:1,3
122:4 170:22 186:2,5 187:10 162:12 165:16 126:12,13,13
195:10 251:14,15 193:16 205:19,20 166:19 167:1,17 134:15 315:21
277:15 305:1 205:20 206:17 169:21 170:8 171:9 changed 92:2 93:4
330:17 209:4 216:10,12 173:10 174:11 102:22 106:1
CAT 69:16 227:7 228:14 235:4 175:8 178:15,19 177:15,16 229:11
catch 89:16 240:4 248:12 252:11,12 179:9,17,19 180:13 234:16 281:11
category 249:4 253:7 284:17 181:12 182:12 285:4 288:21
caught 144:13 293:20 312:1 320:9 184:7 225:15 changes 93:10,11
cause 115:15 159:6 323:22 239:20 240:10,18 94:9 171:3 228:9
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chapel 149:15 112:10,12 114:15 choose 136:12 275:22 class 29:18
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characterization 167:15 176:20 328:1 148:9 158:7 164:1
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112:12 46:21 48:18 chronic 31:17 214:8 168:16 170:3 171:5
characterize 98:12 CHERYL 9:9 267:18 290:12 175:13 178:7 305:6
characterized 194:11 chess 144:10 294:18 295:12 305:15 320:1
characterizing 47:13 chest 69:11 296:4,15 298:19 321:18 325:14
charcoal 274:9 Chicago 278:2 CH.B 8:15 cleared 140:21
chart 121:17 123:2 chief 3:7 4:11 24:4 Ciba 19:14 20:3 274:13,17
charts 95:12,13 27:1 167:22 184:14 Ciba-Geigy 19:13 clearly 36:17 67:10
122:19,22 123:7 186:4 56:22 61:4 97:3 101:13,14
chase 153:8 child 277:2 283:22 circled 103:15 102:1 105:3 117:12
Chase-Temple 279:8 284:19 circularity 251:5 134:1 157:15
chatting 330:15 childhood 18:20 60:6 circulation 30:20 160:15 166:5
ChB 10:12 children 18:18 24:8 273:4 274:16 178:22 211:20
check 92:6,7 28:22,22 32:15 circumstances 223:18 236:7
checked 139:1 261:6 39:14 53:10 55:17 113:10 279:4 272:10 288:14
315:20 55:19,20 56:5,7,14 307:10 318:14 321:19
checks 95:17,18 96:7 118:17 131:4 cisplatin 26:15 42:21 323:13 328:14
121:19 122:9,12 139:21 144:11,15 43:1 60:21 61:16 cleave 273:2
checkups 139:18 152:7 153:9 163:1 63:11,21 86:14,17 Clifford 8:7 11:14
chemo 290:11 163:4,5 166:2,4 101:14,16,19,20 14:6,6 15:14 16:3
chemotherapeutic 167:4,9 208:3 102:1 109:13 148:8 136:16 140:9 145:4
166:8 282:5 283:1 290:13 159:14 161:14 181:10,10 182:12
chemotherapy 22:14 290:19 citations 23:11 182:15 261:5 276:5
24:3 26:6,10,11,13 children’s 4:12,16 cited 47:12 291:2 294:8 298:21
27:3,4,13,17 35:12 5:14 13:16 14:16 claim 92:9 134:9,10 300:4 302:21 303:2
35:19 39:8 42:7,11 24:1 25:18 29:1 234:10 236:6 303:5 332:19
42:14 44:8 45:7,9 35:8 62:4 claiming 236:2 Climbing 282:20
46:15 47:8,10 53:4 chills 31:8 43:15 247:11 clinic 4:3 14:11 116:6
53:6,21 54:8,9 55:9 64:15 85:22 clarification 170:1 139:2 181:15 279:9
60:15,16,18,20 chips 279:16 171:15 304:5 315:20
61:14 63:4,9,10,16 chlopherabine 56:15 308:15 317:14 clinical 3:15 4:11,19
63:17 64:4,7,19 56:17 clarifications 90:1 6:4 9:8,10 12:6
65:15,18 66:2,12 choice 115:17 139:10 171:10,12 240:2 19:4,11,16 21:8
67:2 68:1 78:9 85:7 286:15 290:13 clarify 90:13 98:5 26:8 34:13 36:7
87:8 88:5,10 96:19 chondroblastic 68:12 105:1 106:18 108:1 41:15 52:22 53:11
96:22 97:4,11,12,14 107:15 125:1 131:13 54:5 56:11,13
98:10,12,15,16 99:1 chondrosarcoma 174:12 57:19 59:12,14,20
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76:5 98:20 99:2 44:18 45:18 54:20 311:22 166:20 179:1
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146:14 147:3 149:6 91:16,18 92:5,11,15 238:1 316:14 318:7 324:6
166:13 168:2 92:17 93:20 94:1,3 come 57:4 119:4 326:15 330:11
170:20 182:5,7 94:4,22 95:1,4 96:1 121:20 124:7 135:7 committee 1:5 2:3
184:16,19 185:5,14 106:4 119:11 120:7 138:21 175:12 3:1 10:6 11:7,12
185:18,22 186:3 122:6 129:15 132:4 197:6 198:14 200:8 12:12 13:11,13
187:11,20 188:3,10 132:5 209:21 223:16 15:19 16:8,18,21
188:19,20 189:10 COG’s 91:21 93:8 224:11 247:4 261:2 17:1 23:4 24:4 90:4
189:16,19 196:9 cohort 33:12,14,21 277:17 278:2 90:5 123:21 135:18
197:22 204:1 62:11,14,16,17,19 281:13 287:16 136:1,10 141:1
207:17 220:16 62:20 65:10 68:3,7 317:3 323:21 144:5 145:7 153:18
222:1 223:12 224:7 68:18 73:15 326:16 332:2 154:4 156:7 162:14
225:18,21 226:3 cohorts 85:5 comes 45:5 165:5 164:13 166:21
227:11 230:10 COLESVILLE 1:11 188:22 260:3 170:1 171:11
231:10 267:21 colitis 197:7 272:7 268:13 280:5 178:21 180:1,19,21
304:20 collaborating 169:1 comfort 282:5 182:20 184:13,17
clinically 21:10 36:6 colleague 153:14 coming 118:12 189:9 240:9 267:11
44:9 55:9 117:3 272:18 302:8 128:20 159:5 198:2 275:6,11,20 303:8
203:4 222:4,20 colleagues 41:21 56:6 211:15 303:13 304:7 305:9
239:16 240:22 165:20 167:2 commend 143:14 307:11 317:22
257:16 266:5 327:7 178:14 209:3 163:14 321:6 330:20 332:4
clinician 28:9 257:14 comment 18:9 91:16 committees 24:2
clinicians 189:12 collect 92:16,18 92:22 94:14 95:2 144:14
253:6 120:8 96:13 99:18 104:6 common 18:17 25:1
clock 324:12,18 collected 36:22 40:6 109:11,22 113:2 54:4 60:7,8 74:2
close 45:10 47:9 42:8 43:11 67:15 116:4,11 118:13 85:17 124:8 150:5
212:13,21 217:10 85:11,13,14 88:19 121:13 127:20 219:5,12,19 220:21
closed 20:5 107:18 232:13 235:19 130:16 132:1,14,16 221:3,12 287:16
closer 239:6 267:19,22 157:3,13 162:11 commonly 25:8
CML 267:18,18 collecting 40:2 268:3 169:13,14,15 communicated
CMV 196:11,12 collection 35:7 171:16 175:10 140:21
200:8 College 145:14 177:12 184:5 239:3 Communications
CMV-specific 196:1 colon 194:7 241:12 243:19 294:19
196:8 colonoscope 272:9 245:21 247:15 Communion 282:8
Coagulation 188:5 Columbia 181:18 257:14 259:20 community 57:6
204:16 combat 151:18 270:13 271:6,7 142:9 143:5 307:3
coated 197:13 combats 153:3 315:9 331:15 325:18
codifies 51:1 combination 26:10 commented 141:19 comorbidities 208:16
COG 9:20 20:12,13 61:14 114:15 115:7 161:17 companies 53:15
21:22 23:8,9,10 115:8 117:8 167:14 comments 87:16 company 20:4
28:4,8 34:18 35:8 combinations 26:17 106:20 113:12 132:22 163:14
36:4 37:3,5,7,11 51:11 191:4 123:21 162:9,13,15 165:4 175:19,21
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108:17 120:2 194:12 196:7 223:5 conceptually 322:6 32:13 34:16 37:17
comparable 79:3 297:7 concern 51:18 38:18 62:3 80:3
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263:2 93:21 146:10 172:1 219:22 268:6 269:7 95:6 168:14 188:10
compare 65:14 81:2 188:2 199:7 227:14 321:13 329:11 226:12 232:3 233:9
97:4 162:5 201:3 230:2 234:15 concerned 109:16 237:12
compared 34:2 38:8 completely 110:17 152:8 174:6 176:14 confidence 38:12
39:7 66:20 71:2 233:13 237:9 286:7 concerning 59:1 39:11 40:1 42:4
73:20 76:20 86:8 297:8 322:14 87:16 111:16 126:4
88:9 202:18 227:10 completeness 131:5 concerns 199:1 165:13 306:6
233:11 239:2 241:3 172:18 201:22 224:10 confident 176:4
241:10 249:19 completing 74:3 87:9 226:3 231:10 confirm 20:17
comparing 26:20 87:14 188:6 305:21 confirmation 59:21
35:22 50:5 57:17 completion 187:12 conclude 97:17,18 62:22
80:22 252:20 229:16 234:15 176:11 177:9 225:2 confirmatory 22:1
comparison 35:11 complex 56:11 238:5 330:10 40:11,13 41:8
36:3 44:3 48:3 complexity 143:17 concluded 67:4 170:21 304:21
75:10 77:16 79:21 compliance 54:16,19 141:10 202:21 confirmed 40:4
80:13,17 98:1,3,4 complicate 64:21 concludes 299:1 45:19 55:2 67:18
107:9 110:12,12 69:4 75:17 concluding 242:9 176:12
215:8 230:7 231:18 complicates 81:17 conclusion 38:16 confirms 113:20
232:21 237:16 complication 190:14 39:20 40:2,5 41:7 conflict 10:7 11:13
238:16 241:10 complications 56:8 57:19 88:3 105:22 16:2,4,12 53:17
273:11,14 311:9 150:1 197:3 201:21 326:17 182:13,14,16 183:2
329:2 251:18 279:2,13 conclusions 20:18 300:22 301:2,3,5
comparisons 47:22 310:7 314:14,18 41:16 42:4 84:16 conflicts 301:6
48:2 78:17,20 79:1 complies 19:8 178:18 84:17 102:10 257:5 conformance 46:2
compassionate 109:4 258:5,8 318:10 concomitantly 64:18 confounding 214:20
compelling 73:2 89:1 component 29:22 concurrent 234:13 confronted 250:6
90:11 164:8 166:13 63:6 conditioning 192:9 conjunction 11:21
168:10 178:13,13 components 322:22 193:9,13 208:11,13 22:13 165:3 189:6
211:18 241:8 245:7 compound 252:6 215:3,4 216:6,16,19 224:21
245:14 252:18 295:21 216:19 217:6 227:8 connection 136:7
compensate 70:9 compounded 252:6 228:12 230:21 275:17
competing 32:16 252:14 280:14 232:17,19 235:16 conscious 53:16
223:1 295:18 296:1 237:19,21 243:7 281:13
competitor 17:10 306:13 244:15 245:20 consent 67:20 69:2
competitors 17:7 compounding 253:5 256:4 262:21,22 309:15,17
136:4 183:6 275:14 comprehensive conditions 233:6,22 consequence 51:8
competitor’s 16:17 19:14 235:20 259:16 consequences 45:14
16:21 comprised 208:8 conduct 20:2 57:17 220:16
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236:4 240:21 consumer 2:19 13:21 77:20 78:3 80:7,14 correlation 328:12
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257:8 266:4 310:11 125:21 129:9 172:5 265:4 282:15 186:15 197:14
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considerations 12:8 174:20,22 229:18 controlled 80:18 219:16 221:19
204:7 231:7 280:12 331:20 195:5 198:19 201:7 226:10 235:5 238:8
considered 28:9 35:2 332:19 229:6 304:12 250:20 251:12,17
35:14 40:10 71:19 contacted 71:14 326:18 273:9
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83:2,15 111:11 contained 76:21 CONT’D 3:2 6:1 7:2 197:10 206:3,20,21
125:15 161:15 168:18 7:16 207:3 238:10,11
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234:4 248:10 87:15 206:20 conventional 27:3,13 Cosmetic 59:9
considering 255:4 context 55:21 128:22 106:6 148:10 166:7 cost 42:5 308:16,18
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consisted 63:1,10,18 230:9 242:6 275:7 151:20 178:3 311:8 costs 57:2 307:21,22
150:9 312:13,20 313:16 312:7 couldn’t 197:16
consistency 21:15 317:19 convincing 170:11 255:17 265:4
215:10 217:18 continual 280:4 304:12 280:10 281:22
268:22 269:7 continually 150:22 convoluted 56:22 332:14
consistent 36:16 continue 119:10 cool 285:11 Council 24:1
42:11,13 47:11,20 146:18 238:5 cooperative 19:22 counter 250:17
48:7 49:1 95:19,20 continued 11:1 12:1 21:5,7 22:16 32:22 countervening 256:1
221:4 242:20 263:6 41:11 42:2 139:13 34:17 35:16 44:17 countries 199:19
consistently 141:9 139:17,18 192:18 61:7 62:4 98:14 couple 94:20 112:17
consists 186:20 195:15 201:2 131:3 163:11,13 126:18 155:7
192:13 205:12 251:13 copies 37:9,9 93:22 269:17 272:9
consolidation 148:7 continues 41:9 94:2,3 316:13
constantly 112:14 248:21 copy 17:14 20:11 course 11:22 36:4
282:16 289:19 continuing 83:7 183:10 86:10 87:3 99:11
constituted 30:9 120:9 cord 276:18 100:7 150:19 159:1
constitutes 220:9 contract 17:2 108:15 corn 252:3 253:1 189:7 200:10,11,12
constitution 315:6 contraire 263:12 293:2,3,5 295:18 222:3 224:22
constitutional 87:19 contrast 27:20 56:19 306:13 311:22 230:21 251:10
constructed 70:17 194:4 312:11 292:11 293:10
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consultant 2:20 4:2 177:4 correct 102:22 103:8 cousins 288:18
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183:8 278:10 32:17,20 131:3 C.F.R 17:12 183:8 189:16 191:18
crackers 293:17 134:10 C3a/metabolism 202:13 207:20
cramps 219:4,8,17 cured 40:19 55:5 271:2 209:20 211:4
crap 317:11 161:18 212:13,16 213:14
creams 206:20 cures 161:20 D 214:11,18 215:20
created 195:8 curiosity 325:2 daily 211:13 228:17 216:2,17 220:9
CRF 121:17 123:2 curious 107:14,22 281:12 282:1 222:13 223:17,22
CRFs 37:8,9 43:9,14 154:13,19 241:9 Daly 274:5 226:4 228:21
87:16 88:16 91:8 248:1 258:9 Dame 145:13 149:17 229:17 230:1,8
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95:4 121:20 28:14 59:2 133:18 Dana-Farber 181:5 239:8 242:11,15
crimes 282:11 168:8 184:4 213:12 Dana-Farmer 2:17 243:21 245:7,14,14
criteria 52:4 67:16 313:1 330:6 dangerously 285:21 246:2,3 252:18,19
67:21 108:6 143:4 currently 24:3 27:12 dark 280:19 267:19,21 268:4
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203:13 226:22 168:1 208:14 252:3 22:17,22 23:9,12 274:14 296:12
248:2 249:12 309:3 311:15,17 27:13,14 28:18 303:22 310:11
305:19 CURT 9:7 35:7 36:22 37:5 312:8 319:17 326:8
criterion 46:7 47:21 curve 66:9 79:12,12 40:3,6 43:20 44:1,8 database 37:4,6,10
251:10 127:6 162:5 44:21 50:21 54:20 40:7,8,10,11,11
critical 267:19 274:5 curves 32:19 42:2 56:7,11 57:15 59:5 45:4 95:5,10,14,16
criticize 332:10 55:3 66:22 79:10 67:15 70:22 72:9 96:8 121:18 123:3
Crohn’s 197:7,15 79:14,15 115:13 73:9 76:10,11 207:1 218:6
cropped 159:17 127:12,12 132:21 77:10,10 79:11 databases 92:20
cross 38:13 39:12 165:9,9,11 172:4 82:12 83:19 84:7 283:17
295:10 325:13 84:10,20 85:10,14 dataset 20:11 28:4
crossfire 144:13 cushingoid 219:18,19 88:16,18 91:8,15,18 37:11 38:6 40:13
crossing 325:13 298:8 92:13 94:16,20 40:13,15,18 41:8
CRs 297:7 cut 77:10 300:4 95:4,7,21,22 96:4,7 49:1,2,7 71:3,17,17
crucial 23:19 29:10 cutoff 83:19 84:7,11 97:16 98:1 102:11 71:18 72:2,4 75:15
Cruickshank 243:18 233:19 254:22 102:13 104:13 76:4,6,8,9,12,15,17
244:6,10,10 246:15 cutting 131:11 106:1,2 108:12 76:20,20,22 77:4,12
259:20 260:1,5 cycle 295:7,7,13 112:3,4 117:15,17 81:10,13 82:14
262:15,18 263:17 cycles 63:10,13,20 118:2,9 121:14,18 83:20 88:15,16
314:6,7 323:16 297:2,4 121:21 122:3,9,10 91:9,10,10,19 92:5
325:3,6 cyclosporin 285:15 122:11,17 123:2 93:8,11,15 103:18
crying 285:14 292:12 125:4 127:22 106:8 107:16
CT 100:3,4 147:18 cyclosporine 192:14 129:12 141:17 113:19 117:15
cultures 199:15 cytokine 31:5,7 142:12,14,17 156:9 118:12 119:15
cumulative 210:21 cytokines 190:17 156:18 157:6,22 120:1,5,11 122:11
211:9 226:16 cytomegalovirus 163:11,13 164:8,12 123:12,18 125:8,15
250:20,22 221:2,3 164:15 165:6,8 126:2,7,9,9 129:15
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130:7 131:18,22 220:5 222:7,8 dealing 271:4,5 46:6
132:4,5,12 133:1 226:15,18 229:15 281:4 291:22 deficiency 221:20
142:22 163:8,9 229:18,21,22 death 21:13 28:12 define 268:2
173:20 175:4,4 231:15 232:12 32:16 39:14 41:11 defined 34:22 52:17
234:9 246:9 256:9 237:15 238:19,20 76:13 95:17,19 59:18 85:12,18
257:7 239:9 240:22 245:7 195:21 212:6,8 170:4 201:14,14
datasets 48:10 70:13 248:4,15 249:3,4,17 213:11,20,22 226:22 267:7
70:15,16 76:2 249:17,17,18 229:18 264:22 defines 98:17
91:14,21 92:11 250:21,21 251:1,14 deaths 57:8 72:2,3 defining 29:8
104:22 117:15 259:13 262:20 87:5 88:21 125:7,8 definitive 51:14 52:6
118:8 122:5 123:11 263:1 265:9,20,20 133:1,11 148:4 63:2
141:11 143:6 265:22 266:5,13,14 150:11 192:5 212:6 defy 127:22
234:12 238:2 266:21,21 280:2 212:7 214:1 320:14 degree 235:6 246:12
datatset 143:17 282:7 285:2,5 320:21,21 321:2,3 306:6 332:12
date 69:18 71:13,14 286:14 287:7 288:9 debatable 157:11 delay 49:11 204:12
77:10 92:18 93:3,6 288:17 290:9 296:8 decade 150:7 228:10 delayed 57:8 93:17
108:20 125:21 312:16,16 313:14 230:18 234:17 delayed-release
130:2 138:11 320:4 324:13 decades 250:9 187:1
173:19 174:10 325:15,15 328:13 decadesm 24:12 deliberation 313:18
180:8 232:14 days 76:13 200:3,11 December 84:1,2,3 313:19
dated 94:3 200:18,20 201:12 149:20 174:19,21 deliberations 312:10
dates 28:2 92:2,14 202:16 204:10,19 175:1 delivery 197:13
226:17 205:3,10,10 206:2,5 decent 293:17 demographic 38:19
daughter 282:8 215:12 218:16 decide 117:9 163:1 demographics
288:1 228:18,19 229:7,16 178:8 226:21 227:16
daughters 281:10 229:16 235:10,11 decided 138:11 demonstrable 26:11
Dave 181:4 324:15 248:5 257:15 decision 29:9 33:20 demonstrate 41:9
David 2:14 13:22 258:17,19 259:2 53:17 135:16 204:1 108:16 114:20
16:16 185:20 260:14,16 266:11 245:19 281:13 168:7 223:7 233:17
252:10 266:12 268:9,11,11 290:18 308:13 239:18 248:22
day 141:5,9,16 268:12,17,21 269:2 decision-making 323:11 329:3
147:13,16,17 270:3 271:17 275:3 demonstrated 22:3
148:13 149:18 279:11 281:7,7,9 deck 255:9 27:18 31:10 53:5
163:2 164:9 187:5 286:5 287:19 289:7 declared 103:20 54:18 57:11 81:6
187:5 189:2 192:11 295:8 296:18 297:2 decline 195:2 97:10 211:16 224:2
192:17,19 193:1,2,3 310:14,16,19 322:4 declined 43:17 304:2
194:21 195:11 323:11,14,16 decrease 238:9 demonstrates 21:7
196:7 199:2,20 324:14 decreased 198:8,9 21:10,14 25:17
201:10,19 202:16 day-80 323:10 223:18,20 250:4 42:6 66:9
203:1 204:9,10,14 de 17:11 183:7 298:2 demonstrating 59:15
205:15 209:2,9,12 dead 100:17 125:15 deep 220:22 205:1 217:17
210:7,15,17 211:1,6 283:19 deeper 217:10 demonstration 36:14
211:8,17 212:1,11 deadliest 153:3 defects 121:11 51:5 115:3
212:13,18,19,19,21 deafness 86:12,16 defense 163:8 333:2 Dendreon 144:6
213:10 217:8,19 deal 123:3 295:9 deferred 45:22 46:5 denigrate 247:7

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Department 2:8,15 designations 229:3 187:8 324:3 147:22 149:3 286:8
4:2,7 5:3,8 8:20 designed 26:8 31:19 developmental 56:21 286:19
52:15 145:18 146:8 35:9 44:16 55:22 307:22 died 72:21 73:7
333:1 56:9 65:8 151:18 develops 225:5 83:20 84:14 125:12
departure 288:16 162:4 171:1 206:8 deviate 239:21 125:21 213:9,10,20
dependent 100:15 267:1 305:2 307:6 devising 268:3 218:15 281:17
depending 46:15 329:2 DFS 34:4 36:21 286:10
105:10 193:16 designers 78:4 38:14,16 39:3 45:3 Diego 14:5 181:9
239:3 243:6 designing 157:16 45:11 46:10 51:11 dies 147:22 172:20
depends 128:3 designs 157:14 51:12,16,17,20 52:1 192:4 225:7,8
134:16 234:18 321:6 52:3 82:6,14 diet 279:16
deputy 182:8 desire 214:4 106:13 111:7 112:3 differ 46:15 332:15
Depuy 146:17 desperate 149:13 132:20 176:12 differed 245:2
derived 59:11 152:19 162:21 DFSP 142:11 143:8 difference 42:19 45:8
dermatofibrosarco... desperately 161:11 143:19 144:20 46:20 47:20 48:6
142:11 289:13 diagnosed 24:20 35:1 50:7,15 66:18,21
describe 22:7,10,12 despite 24:7 26:7 37:16 54:22 55:18 73:2 83:1 91:8
23:12 31:15 32:5 28:10 50:12 52:4 61:12 136:21 137:9 100:22 101:5,9,10
59:3 96:17 151:12 278:18 105:2 108:8 110:13
described 36:12 destruction 25:11 diagnoses 26:4 60:11 115:18,20 131:21
70:18 76:8 79:17 detail 168:13 208:5 227:16 132:10 133:17,19
92:7 113:16,16,17 detailed 36:18 75:4 diagnosis 25:13 32:4 155:9 159:15,17
115:3 119:6 132:4 81:21 68:10,15 100:7,8 176:15 203:9 217:5
232:11 detect 69:16 111:7 131:6 137:19 218:5,13 219:8
description 22:21 112:7 128:19 147:15,19 150:16 237:5 239:12 241:8
78:14 318:12 206:14 218:4 204:9 227:3 252:13 246:12 251:3
deserve 153:2,5,9 detected 110:17 259:19 257:21 258:22
design 32:21 35:5,20 detectible 25:14 36:7 diagram 73:12 259:6,8,9 269:2
36:2 42:9 49:9 determination 69:9 Diane 287:9 270:2,20 274:3
64:20 65:21 66:4 69:10 74:5 diarrhea 194:13 315:22 316:6
67:7 78:1,6,11 determine 56:9 57:21 199:11,18 204:19 325:14
101:15 158:4 159:1 72:11 74:17 76:13 280:3 281:2 285:3 differences 43:2
159:8 168:12 determined 16:9 290:4 292:14 47:14,17 48:5 50:3
170:18 203:11 60:20 68:22 69:1 293:12 312:3 91:12 102:18 110:9
206:10 227:18 149:5 182:21 diarrheal 199:19 110:16 115:21
230:13 266:19 devastating 288:3 didactic 145:20 118:14 127:1
294:17 304:19 develop 150:18 249:1 didn’t 94:19 108:10 154:13 155:15,20
319:6,6,14 322:20 298:8 111:22 113:9 114:5 155:20 193:12
designate 70:14 97:5 developed 249:4 126:3,13 173:12 221:17,18 227:18
designated 8:6 14:6 292:20 293:3,5 204:12,20 247:17 228:3,11 230:12,15
35:13 71:1,17 322:12 263:13 272:16 230:19 235:15
181:10 developing 294:3 288:17,19 289:9 238:3 246:1 315:17
designation 187:15 development 19:4,12 323:6 324:19 328:7 different 42:16 66:5
187:21 190:4 19:16 23:2 57:2 332:15 78:12 83:8 90:19
191:17 141:2,13 143:12 die 24:13 27:19 92:19 95:18 98:19

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106:5 125:2 132:12 director 3:10,16,19 discussed 21:20 188:1 189:5,13,16
149:12 150:17 4:19 6:15,18 7:12 28:18 55:6 65:20 189:21 190:12,12
159:3 160:11 177:8 7:14 15:4,5 140:12 78:6 92:2 111:15 191:1,3,9,11,14,16
193:14 196:10 168:2 182:8,9,11 143:9 144:4,9 191:18 192:1,1,3,5
223:11 228:19 276:10,19 166:7 168:13,22 193:1,18 194:5,9,10
229:7 234:19,22 disagree 96:15 234:22 236:16 195:8 196:15 197:7
235:3,9,12,14 115:19 308:10 309:5 197:15 198:7 199:4
238:21 243:5 251:2 disagrees 234:11 323:12 199:5 200:1,15
251:4 265:18 disappears 30:20 discussing 58:21 203:14 204:4 209:6
266:22 278:18 50:14 discussion 11:9 12:15 212:10 214:3,4,7,8
288:6 296:2 314:5 disapproval 180:2 15:18 59:4 69:7 219:13 222:2,21
326:11,16 331:11 disavowing 110:7 75:4 89:22 90:3 224:20 225:6,8,12
differential 263:7 discharged 249:3 126:20,21 132:18 238:14 249:2,5,13
differently 245:5 disclosed 300:17,21 135:5 154:4 156:1 252:14 253:9 254:1
differing 35:16 301:7 169:14 184:8 256:2,5,17 264:8,21
differs 274:4 disclosure 190:2 212:22 225:16 267:6 270:5,6
difficult 21:8 83:5 225:3 278:9 300:18 254:16 256:6,7,8 278:7 279:3,13
105:7 159:18 160:2 disconnect 163:21 269:13 300:9 292:14 294:15
160:7 164:16 175:13,17 176:2,4 303:14 305:9 312:22 326:13,14
268:17 310:17 discontinuation 309:21 316:15 diseases 130:21
315:11 316:10,10 195:12 202:17 319:8,10,12 331:6,7 165:21 186:8 197:5
difficulties 230:10 218:15 331:10 209:6 254:19
240:17 241:6 discontinuations discussions 15:20 321:15
difficulty 112:22 43:6 17:22 90:12 107:20 disease-free 21:18
312:15 discontinue 139:16 108:1 154:8 168:21 26:1 33:2,10 36:8
diminished 222:22 discontinued 119:5 183:18 301:21 36:10 39:19 54:21
277:14 192:16 330:19 331:3,11 65:9 66:9,17,18
Dinndorf 6:20 11:4 discouraged 325:21 disease 11:20 18:19 67:13,13 69:10
15:1,1 58:5,9 76:8 discover 290:16 18:20 20:15 21:20 71:21,22 72:6 75:6
84:15,19 89:12 310:13 22:9 24:13,19 25:4 75:7,13,18,21 77:6
101:7 102:5 108:5 discovered 203:16 25:13 27:20 28:12 77:14 81:16,17
124:11,19 discrepancies 71:4,5 31:22 32:4 33:17 82:19 88:3,10,14
dipeptide 29:21 71:20 72:5,7 76:11 35:4 36:7 44:2 55:8 89:7 93:13 94:11
dipropionate 185:3 discrepancy 71:10 55:14 56:12 57:13 100:8,10,13,14
185:11 186:14,19 157:5 57:20 68:22 69:19 103:3,6,8 104:3
295:2 discuss 49:5 59:1,6,7 73:4 78:15 79:10 105:3 113:7 114:3
direct 79:20 120:13 69:5 73:8 74:5 75:3 84:13 99:12 102:16 124:4 126:21
136:3 252:20 77:13 81:15 82:17 103:1,20,21 108:20 128:22 131:14
275:13 328:12 83:16 84:19 123:13 109:8 112:14 134:10 156:10
directed 89:14 151:6 141:2 156:6 162:16 125:20 126:12 160:16 161:7 164:5
247:16 164:4 167:18 131:1 148:1,10 173:1 175:17 176:3
directing 332:19 180:16 198:18 150:16,18 151:7,10 176:8 177:18
direction 46:14 66:13 225:22 226:3,5,7 151:14 153:4,7 disease-specific
105:10 258:22 244:6 304:4 308:7 165:21 175:13 268:4
directly 30:13 287:12 308:8 331:12 184:20 185:5,12 dismiss 164:20

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disorder 190:14 177:19 178:9 302:14 303:9,15 Doug 272:18
267:12,15 288:4 257:19 263:9 278:1 306:6 307:11 downstream 211:21
disparate 102:10 297:15 298:5,15 309:22 311:13 247:11
disparity 87:7,11 299:14 302:4 310:8 312:14,19 318:4 doxorubicin 26:15
display 215:6 dog 261:16 320:16,17 321:21 60:21 61:16 63:18
displayed 243:21 dogs 33:5 326:5,7,15 109:14 148:8
disposition 49:6 50:9 doing 133:4,6 157:21 door 286:13 dozen 109:1
73:13 158:4 173:3 192:16 doorstep 282:11 Dr 13:12,14,16,18,22
distal 25:6 272:21 200:18 205:8 Dor 11:16 180:17 14:2,4,8,12,14,16
distinction 314:13 249:22 258:14 184:15,16 186:6,12 14:19,21 15:1,3,5,7
distinguish 175:3 260:10,12 308:4 190:7 244:11 15:9 16:20 17:1,4,9
distinguished 145:6 310:4,20 311:4 278:11 294:15 18:15 19:10 21:14
distorted 285:7 324:2 325:22 326:6 328:2 22:5,7,11,15,19
distribution 37:20 329:17 Dorchester 277:17 23:1,1,7,9,12,17
disturbance 303:8 dominant 194:8 dosage 193:18 29:16,16 31:14,14
division 2:10 3:7,20 196:15 213:11,22 277:13 280:1,2 32:5,9,9 33:6,8
4:11 6:19,22 7:14 donor 190:16 192:12 dose 27:6 54:11,12 43:20 44:11,15
7:19,22 9:4 15:3 206:17 207:2 63:15,15 64:3,3,5,6 52:7,10,17 53:1,3
52:12 182:10 188:4 209:18 210:13 64:7,14 74:18 85:9 57:15,15 58:2,5,9
190:3 199:8 204:15 215:3,5 217:7,12,16 114:8,8,14,21 134:4 58:14 59:6 69:5
dockets 17:19 183:15 235:4 244:18 189:1 195:15 73:8 74:21 75:2
docs 287:15 259:10 264:1,5 196:11,12 199:1,2,4 76:8 84:15,19
doctor 115:17 137:20 279:8,9 199:6 201:8 211:1 89:12 90:4,5 91:4
138:16 139:1 donors 206:17,19 211:8,9,13 218:16 91:15 92:1,7,22
147:10 don’t 90:7 91:2 94:14 224:7 250:22 94:13,17 95:2,3
doctors 138:15 281:1 98:11 100:18 251:12,15 273:13 96:9,12,14,21 97:20
287:2 102:19 105:18,20 273:14 274:8,11 97:22,22 98:3,6,8
doctor’s 279:21 106:11 107:7,16 277:13 282:19 98:11 99:2,6,7,17
document 45:2 69:20 110:3 112:20 113:3 296:20 99:17,19 100:20
93:21 96:17 174:14 115:12 117:2,7,10 doses 64:8,19 70:7 101:7,7,9,12 102:5
174:15 186:9 119:7 121:17,18 74:10,17 101:20 102:8,9,14,15,21
202:11 207:10 128:9 129:6 130:11 195:2 210:21 229:8 103:11,16 104:4,8
documentation 132:2,13 133:3 241:3 297:12 310:5 105:1,6,16,18,20
45:16,17 93:6,17 152:9 156:12 dose-compressed 106:9,11,20 107:2,7
118:14 123:12 161:22 165:1,4 27:4 107:12,13 108:5,10
documented 36:22 166:8,15 167:14,22 dose-escalation 109:7,10,11,19,21
43:10 71:11 77:2 170:1 171:21 173:5 115:2 110:1,5,6,7 111:9
87:16 88:16 122:21 176:22 178:5 dosing 34:14 115:1,1 111:10,19,22 112:2
123:1 171:5 176:18 194:16 247:7 201:3,5 228:17 112:16,17,17 113:1
235:21 305:6 251:14 252:22 235:17 297:11,15 113:1,3 114:4,16
documents 17:18 253:4,18 256:18 dosorubicin 63:11 115:6,7,8,9,19
92:11 94:22 183:14 257:15 260:5 279:4 double-blind 226:12 116:3,9,10,12
211:10 314:19 279:6 284:6 287:10 227:12 117:11,12,18 118:6
doesn’t 100:16 108:7 291:17 292:8 297:6 doubt 161:19 163:14 119:2,3,17 120:5,17
116:19 160:14 298:6 299:10 302:3 168:20 120:22 121:1,4,13

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123:10,18 124:3,6,7 232:1,11 234:14,22 dramatic 152:10 232:15 253:3
124:11,18,19,21 235:14 238:4,7 270:20 255:10 266:16
125:15,18 126:15 239:5,20 240:11,11 dramatically 106:2 270:17 272:21
126:16 127:6,7,8,10 240:13,18,19 241:5 drastically 288:21 275:1 280:8 282:1
127:17,17,20,22 241:7,17,19 242:1,2 drawn 92:19 288:11 294:3
128:2,7,10 129:3,13 242:2 243:17,17,20 dread 247:5 295:13,16 298:11
129:16 130:1,4,6,13 244:11 245:4,21 dream 149:17 298:15 305:20
130:15,15,19 246:4,5,14,15,17,18 dreams 153:8 306:1,4,9,15 307:1
131:10,11 132:1,7,9 246:19,19 247:13 drill 102:13 307:2,5,21,22
132:13,16,19 247:14,16 248:11 drilled 216:16 262:5 308:16 311:15
133:13,14,15 134:2 248:11,12 250:3,19 drink 284:20 314:17 317:3,5,13
134:17,20,22 139:4 251:22 252:8,8,10 driven 66:19 80:12 322:12 323:6 324:4
139:4,15,22 141:16 253:10,11,12 80:17 88:4 100:15 327:1 328:22 330:5
141:18,20 145:6,6 254:10,10,12 255:4 100:16 127:3 331:9,12
145:17 146:3,11 255:7,7 256:7,7,22 156:22 209:22 drugs 1:5 2:3 3:1
149:1,5 153:17 257:1,1,13 258:3,6 214:11 215:3 244:7 26:15 28:21 29:5
154:6,10,11 155:2,3 258:9 260:1 261:15 252:15,17 269:6 34:10 58:22 63:13
155:5 156:5,15,15 261:16 262:15 320:11,13 98:16 111:2,11
156:16,17 157:2,3 263:12,20 264:13 drives 127:15 210:4 115:13,22 116:18
160:4,5 161:2,9,10 264:14,20 265:13 driving 196:20 116:18,19,20 117:3
161:10,10,13,17 265:21 266:8,9 243:22 263:10 117:4,5,6 134:3,4
162:3,17,18,18 267:1 268:7,8 dropped 56:22 140:2 178:6 188:8
163:11 165:16,19 269:15,17,18,19 129:19 279:18 193:17 201:17
166:22,22 167:1,2 271:7,20 272:3 drops 248:14 205:17,18 284:21
167:13,17,18,21 280:6 294:13 drug 1:1,2 6:11,16 285:9 288:21
169:1,9,21,22 170:4 299:12,17,18 7:1,12,14,19,22 290:12,16 292:6,9
170:7,9 171:14,15 301:16 304:9 8:10 16:10 30:7 298:13 306:12
171:21 173:10,10 305:14 306:18,19 54:13 56:14,15 307:17
173:12 174:11,12 307:16 308:9,12,17 58:10 59:9,10,16 due 41:20 42:19 43:1
175:2,5,6,7,11,21 309:5,8 310:10 74:8 111:13,14,17 43:2 49:17 75:9
175:22 176:6 311:10,10,19 117:10 133:22 77:15 112:8 149:22
177:12 178:15,20 312:10 313:21,22 135:14 141:2 171:2 187:15,21
179:4,5,6,7,8,10,11 314:10,11,12 143:12 149:6,16 192:5,21 229:12
179:12,13,14,15,16 316:17,17 318:15 151:5 152:1,16 238:2 279:13
179:17,18,19 318:16,19,20,22 153:3 154:17 284:21 285:9
180:18,22 181:4,6,8 319:1,2,3,5,7,11,15 164:16 168:16 287:13 298:6 305:3
181:14,16,19,21 320:2,4,8,9,10 169:19 178:4,8 DUGAN 278:15,18
182:1,3,5,7,9,11 321:10,22 322:9,11 182:10,22 186:13 Duke 5:9 186:5
183:5 184:8,12 322:18 324:9,10 186:20 187:10,15 254:11,13 311:11
185:4,7,9,13,17,20 325:3,16 326:6,19 188:5,8 189:11 dull 147:7
186:1,3,11 189:15 326:22 327:8,11 190:4,4,5 197:12 durability 200:21
189:18 190:1,1 328:1,1,5,13,19,20 199:8 201:20 202:16 205:3 210:6
202:13 225:15,16 330:1,1 331:5,15,16 202:17 204:16,21 323:4,11

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durable 204:17,22 Eckhardt’s 141:20 223:20 244:14 electrolyte 101:1
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282:21 286:22 254:18 277:5 145:7 166:2,3 293:9 294:15
291:6 306:13 324:1 286:22 287:9 289:1 171:22 184:13 312:22 326:13,14
326:3 290:3 297:14 203:10,21 213:13 graft-versus-leuke...
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187:2 188:11 191:4 311:6,14 318:7 247:8,10 259:15 GRAHAM 9:9
215:15 222:2,13 319:5,21 320:14 264:4 265:11 284:5 grams 134:6
223:9 227:1,20 324:9 328:5 goodbye 281:18 grandfather 138:18
228:2 267:5 276:22 goal 32:14 35:20 284:16 grant 52:18 146:16
277:3 282:12 60:17 325:1 Gooley 186:1 202:13 187:10 278:10
284:21 285:16 God 288:8 292:12 320:4,8,8 granted 16:15 17:4,9
287:16 295:2 296:9 goes 195:16 292:15 gotten 249:11 314:2 183:5 187:21 190:4
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give 15:19 78:14 90:9 123:19 131:9 grab 286:17 311:7,14 graph 79:16 127:1
117:5,6,7 134:14 134:18 135:11 grace 288:8 graphic 210:22
167:14 169:18 149:3 154:3 156:2 grade 42:8 43:11,13 graphs 47:6,8,9,10
192:8 222:2 257:6 157:17 162:12 85:11 86:3,19 47:11 48:9,12,14
272:8 277:3 278:13 163:18 165:13 137:1 191:8,10,16 49:20 50:2,6,7,11
312:13 166:10 175:8,10 191:17,21,22 192:4 50:15 164:3
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64:18 86:5 107:17 190:11 193:8 grades 191:2 grateful 143:7
114:9 141:14 150:1 197:19 209:20 grading 191:2,3 graveside 288:11
169:16 187:4 218:6 239:21 gradually 30:22 gray 33:15
192:11 194:21 240:15 242:10 graduate 145:13 great 97:1 151:16
195:3 200:20 243:10 247:5 250:1 293:22 255:16
207:17 208:11 253:17,21 261:1,13 graduated 146:7 greater 68:9 70:6
209:9,20 245:19 263:7 266:20 269:3 graft 184:19 189:20 73:18 74:16 85:22
266:10 285:22 270:9 274:21 191:6,8 192:22 86:21 203:1 218:17
gives 30:3 301:9 276:16 284:14 212:9 256:4,16 219:10 227:22
giving 133:22 209:14 290:4 291:11 292:5 267:5 292:5 228:4 230:22
glad 103:15 294:5 299:21 graft-versus 185:11 239:10 268:6
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143:8,19 144:20 303:10,19 304:4 249:1 295:22
global 242:8 305:17 306:1 graft-versus-host green 51:19
glucocorticoid 220:1 307:15 308:12 185:5 189:5,16 Gregory 5:10 14:16

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grew 281:12 265:13,14 266:18 296:16 297:22 156:16 160:4,5
grief 332:8 291:15,20 292:10 298:17,19 306:12 179:12,12 181:4,4
grim 150:20 302:3 305:14 317:8 313:3,4,5,8,16 242:1,2 244:12
ground 124:9 317:11 321:13 245:4 246:4,14,17
group 5:14 14:17 guidance 144:18 H 253:12 255:7
21:8,19 22:16 24:2 guided 34:13 H 5:10 264:13,14 318:19
29:1 33:17 34:4,21 guidelines 235:22 habitus 219:18,20 Harrington’s 256:8
35:8 36:10 37:14 237:1 hair 285:7,9 hasn’t 289:21 307:13
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44:17 61:7 62:5,5 gut 194:5 197:21,21 197:18 227:5 hates 288:22
106:5 114:18 125:2 200:17 272:18,22 290:20 291:10 haven’t 124:19
127:3,15 130:8 274:15,15,19 284:2 293:19 317:21 164:14,19 165:14
131:4 151:1 158:19 287:13,21 291:12 323:20 330:20 255:21 270:15,22
158:20 159:14,17 319:19 hallmark 212:14 havoc 282:12
161:1 163:11,13 GVH 190:5 191:9,19 270:1,4 Haylock 2:18 13:20
216:21,22 217:2 192:13,16,18,21 hampered 282:14 13:20 179:13,13
218:18,20,22 219:5 193:2,14,21 194:3 hand 113:17 159:20 181:2,2 318:18,18
219:11 220:20 194:19 195:4,21,22 159:20 329:9,10
221:9,10 239:12 196:20 197:17 handle 102:9 hazard 38:11,22
245:13 246:7 198:4 199:10,12,18 handouts 296:13 39:10 41:10 45:10
247:21 251:20 200:17,22 201:7,9 hands 165:1 280:9 46:21 47:2,12
253:15 254:9 203:15 204:9 302:20 48:18 79:2,5,22
255:19 256:16 205:12,14,16 happen 153:13 80:10 81:11 126:3
259:1 262:3,13,20 206:12 212:20 157:17 247:10 126:5,7 131:17,19
262:21 263:13 262:3,9 263:15 happened 118:2,3 160:12 209:14,22
264:7,19 269:1,4 309:11 311:3,4 129:21 130:2,11 210:11,11 215:21
273:3 274:12 310:1 312:2 313:5 326:1 198:16 249:12 216:4,7,7 218:1
313:10 314:3,15,15 GVHD 184:20 266:2 285:19,20 238:12 260:8 263:3
315:3,5 316:7 188:11,21 198:5 323:14 330:14 320:20,22 321:2
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27:9 32:13,22 206:14 209:9,15 happens 93:3 127:15 185:8 225:11 279:5
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126:20 200:19 222:14,19 223:9,17 176:4,17 194:1 headache 31:8
202:20 208:6 219:9 224:6,8 227:1,20 248:15 327:6 headaches 86:1
221:8,18,18,22 228:4,4 229:6 harbor 32:3 headed 148:15
246:13 257:16 232:16 237:18 hard 20:20 111:15 heads 289:12
259:6 276:13 316:1 241:1 256:21 129:3 201:10 healing 287:18
321:19 276:22 277:3 203:20 204:17 Health 3:10 5:13
growth 24:21 146:12 279:13 281:4 249:19 258:17 145:22
guarantee 95:14 282:11,15 283:9,13 270:6 280:7 287:5 healthy 19:19,20
328:11 283:14 284:1,21 289:18 290:20 hear 13:8 123:21
guess 98:18 112:18 285:10,16,22 291:5 315:1,7 164:3
127:12 168:19 286:16 287:13 Harrington 2:14 heard 23:21 28:6,7
218:12 247:15,16 289:17 290:9,12,22 13:22,22 16:16 120:7 149:1 150:5
248:1 252:5 254:3 294:18 295:2 296:4 117:11,12 120:17 172:9,17 226:9,10
122:15,20 123:8

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227:9 228:13 229:5 heterogenous 227:15 histology 200:7 hospitals 290:21
230:6 264:15 HFD-21 8:9 historic 33:14 34:2 host 185:12 190:17
270:22 287:6 Hi 254:12 historically 99:10 199:5 214:3 249:2
291:20 311:16 Hickman 249:8 history 19:3 56:21 282:21
316:22 hierarchical 89:6 61:3 95:20 122:13 hostage 290:9
hearing 11:8 12:13 high 42:3 59:13 151:14 322:12 hostilities 192:21
42:17 86:13 121:10 143:18 147:5 224:6 hit 280:7 289:9,21 222:18
121:11 129:10 229:12 277:13 hit-or-miss 284:4 hours 31:5 149:14
135:10,12,17,22 282:19 306:6 HLA 206:18 217:12 282:2 285:2 292:15
180:6 186:18 261:3 higher 42:18 86:15 264:4 293:18
261:7,14 274:21 101:3 111:4 153:7 HLA-matched House 149:11
275:5,10 276:4 155:13 189:1 206:17 245:1 Houston 149:8,10
278:11 299:1 196:11,12 208:7 hoc 267:22 268:4 151:9
hears 189:10 211:13 216:3 217:2 Hockenbery 185:20 Howard 145:22
heart 142:5 288:20 218:19 241:14 252:8,10,10 HPA 219:21 223:12
289:22 244:22 296:21 hold 52:13 53:14,15 226:19 229:12
held 61:4 290:9 higher-risk 209:5 163:12 293:22 270:16 271:8,13,16
Hello 291:4 highest 55:3 280:2 holding 274:15 HPA-axis 238:17
Helman 4:18 13:14 highlighted 259:8 home 137:6 138:2,12 239:1,15
13:14 107:12,13 highly 41:5 51:22 149:3 203:6 204:12 Huard 146:11
146:3 156:5 161:2 54:5 59:20 170:18 289:9 332:2 hug 288:9
161:9 167:18,21 201:22 222:19 honestly 328:6 huge 115:18,20
169:21 179:16,16 304:19 327:1 hope 66:1 78:8 140:5 164:16 321:21
Helman’s 162:19 high-blood 285:21 144:11,17 149:13 hugged 284:15
help 199:7 242:5 high-dose 11:22 189:9 255:16 Hughes 145:22
284:3 285:6 329:17 60:21 63:11,18 270:10 294:4 human 274:7
helped 140:5 245:13 109:14 134:7,8 327:13 333:2 humans 196:22
245:16 306:10 161:15 189:7 192:6 hoped 65:14,17 humor 147:9
helpful 307:13 193:5,22 194:20 255:22 hundred 19:14 35:3
hematologic 208:7 224:22 229:6 hopefully 90:8 62:6,7,13,19 85:5
225:7 227:3,15 238:11 239:11 hoping 193:19 167:7,10 273:19
267:12,14 246:21 248:20 horrible 288:6 hunt 242:10,15
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hematology/oncolo... 62:10,18 63:1 horse 292:7 18:11 58:2 89:12
2:6,10 3:7 181:20 67:17 hospital 4:12 8:17 98:8,18 99:5 102:8
hematopoietic high-resolution 13:17 22:7 137:9 105:18 106:9,18
184:22 192:11 100:4 137:15 203:5 107:4,12 109:5,9
208:21 247:2 high-volume 199:18 279:12 281:6,19 111:10 112:16
hepatic 67:20 HILTON 1:10 283:13 286:5 287:8 115:11 116:3
heralded 142:9 hinges 117:17 291:14,16 117:11 123:15,22
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135:2,11 141:18 249:8,10 45:16 53:16 57:4 115:2 169:12
145:6 153:17 hypercalcemia 58:17 61:6 68:16 185:18,22 187:20
154:10 155:22 314:22 70:13,15 76:3,6,12 188:2,15,18 189:19
156:2,5 157:2 hypertension 219:17 76:15,20,21 77:11 327:15,15
160:4,21 162:12 314:20 315:14,14 82:6,11,14 88:22 ileostomies 272:20
165:16 166:19 hypertensive 298:9 91:10 92:10 93:21 ileum 197:13,18
167:1,17 169:21 hypocalcemia 219:3 94:18 107:17,21 ill 224:18
170:8 171:9 173:10 316:4 108:10 130:9 132:2 illness 197:17 277:22
174:11 175:8 hypophosphatemia 136:20 140:18 illustrate 47:6 151:8
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179:17,19 180:13 hyporesponsiveness 145:9 illustrated 32:18
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182:12 183:5 184:7 hypothalamic-pitu... 93:15 196:9
225:15 239:20 226:19 238:16 ifosfamide 26:16 illustrates 39:2,21
240:10,18 241:4 hypothesis 171:5 61:17 63:5,18 42:1 43:21
242:1,2 247:13 223:7 305:6 79:19 97:7 115:14 imagine 277:9
253:10 256:22 hypoxia 219:13 115:14 116:7,7,15 284:19 287:18
257:10 260:22 H.A 2:5 134:5,7,8 158:14,19 329:4
261:11 264:12 159:14 161:6,19,20 imaging 69:14 99:10
265:7,14 266:8,18 I 165:3 99:13,15,21
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269:18 274:20 ice 279:16 287:3 65:16 101:1 171:2 227:7
298:22 299:3,6,10 ICH 236:1 237:1 ifos-added 133:17 232:17 237:20
299:12,14,17,20 ICU 285:17 ignorance 99:9 305:3 323:15
300:2,5,10,19 301:2 idea 90:16 128:20 Ignore 274:9 imbalances 208:6
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302:11,14 303:7,10 161:20,21 198:3 ignoring 157:22 immediate 229:1
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306:17 308:6,14 ideal 319:13 53:1 84:21 85:19 323:6
309:1 310:3 311:12 idealized 195:13 97:10 121:6,9 immediate-release
312:9 313:20 identical 221:21 142:13 166:13 186:21
314:11 316:14 264:5 186:3 187:12 immune 190:17
317:14 318:4,11,21 identified 42:15 188:14 191:10,16 192:11 193:6 196:1
318:21 319:4,9,13 61:19 68:7 69:19 191:17,21,22 192:4 198:10 221:5
319:16 321:5,13 70:20 71:4,20,22 203:15 227:20 223:21 256:10
322:10 324:5,8 72:2 76:11 77:1 228:1 267:5 287:13 285:15
327:5,10 328:19 96:5 121:22 239:16 309:19 327:16,16 immunity 30:1
329:7,21 330:8 identify 178:22 240:5 IIB 53:3 immuno 315:5
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333:4 identifying 100:9 21:1,3 22:3,14 32:5 192:22 222:18
Hutchinson 185:9,21 128:4 32:13 34:15,16 314:5
186:1 187:9 209:4 IDM 8:14 9:6 10:9 37:6,8 42:6,7 43:6 immunologist 18:21
216:12 252:9,11 13:8 18:21 20:7,11 44:4,15,18 49:9 Immunology 6:6
320:8 323:21 20:19 23:10 28:3 50:18 51:19 54:8 immunosuppression
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40:8,13 44:22

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292:11 296:5 298:2 importantly 43:3 206:1,4 207:4 indicated 43:9 61:11
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impact 80:4 99:13,21 improve 24:17 26:13 45:13 48:6 49:2 189:4 224:19
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262:13 267:6 54:22 133:19,22 108:6 199:8 203:12 indicators 38:20
331:11 177:10 224:8 329:4 incomplete 219:22 individual 66:12
impacted 82:10 improvement 24:11 239:8 80:22 109:21 123:7
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imperative 163:20 44:10 50:17 55:10 inconvenience 167:9 individuals 54:13
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implies 191:17,22 improves 18:16 41:7 95:15 96:8 329:16 275:7
implore 153:13 inability 283:3 increase 26:5 53:6 induces 31:3
imploring 169:10 inaccuracies 70:20 54:6,9 70:8 232:9 induction 11:22
imply 173:13 inaccurate 71:12 237:11 238:12,22 101:17,21 148:5
importance 23:19 inadequate 72:10 251:12 255:12 189:7 200:10,11,12
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189:11 202:2 230:1 136:6 210:16 164:21 212:9 213:11,21
238:15 242:17 226:16 236:6 IND 61:4 187:9 221:11 238:12
245:10,22 246:8 275:16 321:18 295:5,6,11 307:19 infections 193:6
254:15 255:8 256:6 included 21:21 23:7 308:15,18 330:2 194:1 198:12 202:1
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220:19 221:14 270:17 329:15 209:17 210:13
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298:13 322:13 62:2,21 65:8,22 88:6 157:18 160:6
infiltrates 221:13 initially 243:18 267:4 69:9 75:3 77:18 interest 10:7 11:13
infiltration 31:13,16 295:17 85:3,5,10 87:5 16:2,4,9,12 17:11
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inflamed 272:14 initiated 19:21 49:13 228:16 229:21 144:12 182:13,14
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information 17:16,21 288:10,22 68:18 219:2 104:14 238:12
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infosfamide 168:21 69:11 71:6,6,8 77:3 104:7,8,11,12,14,21 international 61:2
infuriating 150:21 122:2 134:8,13 105:4,7,12,22 106:6 interpret 83:6 158:9
infused 192:12 institutional 27:9 106:12,15 107:11 158:16,17 160:12
infusion 87:19 institutions 62:19 110:19 117:16 164:15 216:22
248:16 95:7 96:6 127:18 128:3,11,16 246:11 274:14
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104:15 105:9 184:16 328:5 44:12 45:2,12 I’m 15:22 93:7 98:16
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intolerance 293:3,4 194:3 196:19 329:13 175:8 180:22 181:1
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intuition 120:19 83:16 112:11,19,21 269:3 271:12 273:4 309:9,15 311:6
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59:6 126:19 271:19 274:12 318:16 324:9,10 localized 25:13 44:2
layers 30:5,13,22 Levine 272:19 325:16 44:4
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lead 185:4,21 186:2 22:6,7 23:12,17 Link’s 256:7 lock 207:1
206:6 219:7 29:16 43:20 57:16 lipid 30:2,3,7 lodging 136:6 145:10
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leaders 28:19 177:12 178:15 liposomal-formula... logical 151:22
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leads 79:22 100:7 licensed 190:5 liposome 31:1 125:22 207:7
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leaves 277:14 282:12 283:8 listed 108:6 218:8,12 292:12
lecture 164:7 287:20 290:7 236:14 longer 33:22 41:15
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20:19 108:15 248:18 139:2,3 145:19 145:14,17,21,22
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marched 208:22 Math 7:8 156:20 157:17 medicine 2:7,8 3:8,15
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Mark 7:7 9:11,19 matter 116:19 326:10 327:7 286:1 325:20
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113:20 287:8 160:14,15 265:19 meaningful 21:10 meet 52:3 59:17
marked 27:20 102:1 299:14 302:5 44:9 54:6 55:9 76:1 143:10 240:12,20
297:10 matters 16:18,22 83:18 89:10 106:17 240:21 284:11
markedly 25:15 17:3 117:3 203:4 207:16 meeting 16:6,12
26:13 Matthew 140:10,12 221:16 222:4,14,20 17:20 23:19 135:18
market 57:1 100:13 284:11 288:13 224:9 240:22 259:6 136:8 142:6 144:7
311:15 Matt’s 287:9 316:8 327:7 180:16 182:18
marketed 186:16 maximum 54:12 means 123:22 130:1 183:2,16 275:6,18
197:15 330:6 64:13 128:15 156:10 158:9,15 330:21 332:21
markets 178:8 266:10,11 159:20,20 203:5 333:6
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173:8 286:18 181:15 meant 282:15 297:5 meets 46:7
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marrow 208:20 294:13,13 measured 188:21 member 99:19 141:5
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248:16 259:10 149:11 185:4,7,9,13 mechanism 52:17 members 2:4 3:2 4:9
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325:18 243:17,20 246:18 307:17 162:14 170:1
marrow-ablative 246:19 247:16 medial 15:1 171:11 174:13
314:15 248:11,12 257:2 median 38:15 39:18 178:21 180:19
marshaled 272:3 264:20 271:7,20 40:15 41:4 72:16 184:12 304:6 321:6
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1:13 309:8 310:10 250:22 296:19,22 Memorial 8:21 22:12
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mentioned 94:19 161:15 192:15 milligram 64:11 minute 91:16 119:18
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144:17 231:13 methylprednisolone 195:10 211:1 minutes 31:5 131:8
239:6 247:19 250:3 189:8 296:7 229:10 135:8 261:2 292:16
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mesenchymal 68:11 31:15 32:5,9,10 187:4,5 199:2 mirror 289:1
mess 287:11 53:1,3 57:15 96:12 251:9 273:17 274:1 miserable 286:8
message 218:12 96:14 97:22 98:6,8 274:7 280:2 296:8 mismatched 217:12
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metabolism 273:5 110:1,5,7 111:19 milliliters 199:20 Missouri 3:21 5:17
metabolite 220:14 112:2 119:17 Mills 8:13 10:10,15 14:13 181:18,18
271:11 273:8 274:2 130:15,19 133:13 18:15,21 19:10 mistake 324:11
metabolized 272:17 155:3,5 161:10 29:16 32:9 91:4 mitigation 51:18
metabolizes 30:22 162:3 175:22 176:6 92:1 94:17 96:9 mobile 41:5
metastases 26:4 32:2 mic 300:4 99:17 103:16 modality 69:15 151:5
60:11 69:17 146:13 Michael 3:3,18 14:12 108:10 109:7,19 model 32:20 46:11
147:19 148:3 180:22 181:16 113:1 114:16 115:7 48:17 216:1
150:12 151:2,19 318:16 115:9,19 116:3,9 models 196:21
152:2 154:16 Michael’s 264:16 119:2 120:5,22 moderate 54:14 86:3
155:13,14,16 177:2 Michigan 2:11 14:9 121:13 124:21 moderating 185:17
metastasis 25:14,15 181:13 300:14,15 127:17 129:13 240:15
metastasized 31:20 300:22 130:1,6,15 132:1 moderator 189:18
metastatic 21:19 microcospy 30:11 155:2 173:10,12 modern 220:8
35:4 36:7 44:2,5 micrometastatic 175:2,6 modest 140:18
55:8 62:17 68:2,15 151:9 mind 105:19 164:14 modification 37:11
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meta-analysis 215:9 microphones 178:21 mini 193:9 132:3
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meter 64:8,11,12 31:22 32:3 277:13 305:5 93:10
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method 69:16,20 middle 50:2 minimizes 329:1 mofetil 193:15,17
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methods 36:20 78:15 149:7,19 Minnesota 181:15 Mommy 285:6 286:8
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monitoring 16:17,21 mothers 288:10 79:12,13,15,15,19 multilayered 30:10
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137:18 139:14 254:17 286:5 88:10 90:19,20 multisystem 190:14
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184:21 189:2,2 43:19 44:7,8 45:5 MTP’s 57:7 314:15
191:22 192:4 213:6 46:14,20 47:4 mucosa 197:21 myeloablatives
214:22 215:19,21 48:13,15 49:10,13 199:12 272:10,14 244:21
217:19 218:2 50:11,12 52:18 273:1 274:15 Myers 5:15 13:18,18
222:15,16 223:2,2,5 53:4,5,10,12,15 mucosal 194:8,11,16 133:14 161:13
226:18 246:2 54:3,7,11,17 55:1,4 mucosis 287:6 179:14,14
251:21 313:14,15 55:8,19 56:2,19,21 mucositis 247:2 M.B 8:15 10:12
320:4,6,13 57:4,17,18,22 58:12 muddies 156:19 M.D 2:5 3:3,9,14,18
Mortimer 3:14 14:4 58:19 59:2,8 60:2,4 Mullen 277:16 4:1,4,10,14,18 5:10
14:4 99:6,7 100:20 61:4,11,18 63:7,14 multi 27:8 6:3,14,17,20 7:11
179:10,10 181:8,8 63:15 64:2,3,5,17 multiagent 22:14 7:14,17,20 8:19 9:3
241:5,7 314:11,12 64:22,22 65:5,7,15 42:7,14 61:14 9:7,9,13 10:17,21
318:20,20 328:19 65:17,18,19 66:8,12 115:10 11:4,11 12:4,7,11
328:20 66:12,14,21,22 67:1 multicenter 21:3 14:2
Mosbacher 52:14 70:1,4 73:6,18,19 62:3 170:17 188:15 M.Sc 8:7 11:14
mother 137:9 147:9 73:21 74:8,12,14,16 191:19 203:17
149:8,10,14 277:2 77:20 78:5,18,18,19 226:11 234:19 N
286:19 290:6 78:19 79:2,2,3,4,5,6 304:18 N 2:1 11:1,1 12:1,1
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78:21 136:18 49:4 52:1 57:21 270:19 295:5,6 nonresectable 62:18
140:11 145:8 113:11 132:14 304:6 325:19 85:3
184:14 187:6 145:1 161:11 newly 35:1 54:22 nonresponders 250:8
240:14 278:1 165:12 166:16 61:12 296:14,19,22 297:3
300:13 169:18 170:13 news 147:20 279:6 nonspecific 273:2
named 186:10 183:21 187:22 Nguyen 136:17,18,19 nonspecified 232:3
names 180:20 204:3 224:5 262:2 nice 262:12 286:17 nontoxic 327:3
Nancy 7:20 12:7,11 299:21 303:17 Nicholson’s 280:19 non-clinical 19:11,13
182:5 225:20 304:14 307:4,14 night 145:10 290:2 non-Hodgkin’s
national 4:22 6:8 needed 117:9 143:17 nightmare 280:15 278:20
19:5 20:1 21:5 189:1 204:2,17 nightmares 288:6 non-laboratory 86:6
35:16 145:21 146:4 215:17 nights 162:19 non-marrow 315:4
168:2 181:19 needing 165:20 nine 76:22 168:1 non-matched 264:1
natural 99:11 151:14 needle 137:15 284:14 286:2 291:7 non-MTP 117:22
242:16 needs 78:3 162:21 296:14 non-myeloablative
naturally 198:16 201:13,15 203:19 nineties 19:12 193:22 208:11,13
nature 47:7 118:7 negating 260:20 ninety 70:5,6 216:15,20 227:10
192:10 negative 149:21 Ninety-eight 70:2 228:12 230:20
nausea 86:1 87:20 199:16 200:8 Ninety-five 40:21 237:21 243:2,7
194:13 199:11 negative-nitrogen ninety-three 62:7 244:1 245:13 246:7
219:14 277:8,9 248:18 nitrogen-balance 253:15,18 254:6,7
284:9 293:13 312:3 negotiates 330:9 248:19 255:14 257:3
nauseated 249:9 negotiation 116:1 nocardia 221:8 261:19 262:9,22
NCI 13:15 34:18 negotiations 326:20 nodules 31:11,15 263:4 314:3,13
52:18 neighborhood 251:9 33:16,18 non-myeloablatives
NDA 11:3 20:21 neoadjuvant 60:16 noise 259:18 260:2 246:10
21:21 40:9 61:10 63:2,10,17 98:10,22 nomenclature non-myeoablative
76:2 103:19 142:19 150:13 186:18 232:19
180:16 Nerf 287:1 nominal 82:15 non-prespecified
nearest 296:19 Network 276:7,11 157:10 237:10
nearly 143:15 148:4 never 45:20 92:9 non 159:13 193:8 non-randomness
227:5 228:10 110:8 143:11 216:5 244:15,20 172:11
230:18 279:17,20 148:12 152:17 255:12 262:5 non-resectable 68:2
NEBY 9:13 218:22 272:11 263:10 312:18 non-responders
necessarily 56:10 273:3 281:17 314:14 297:14
91:2 92:20 95:5 283:10 286:11 Nonclinical 9:16 NON-VOTING 6:12
249:6 263:10 310:8 289:20 307:4 31:21 7:2
318:4 321:16 322:15 nonhematologic normal 196:3,6
necessary 66:5 78:12 328:15 86:19 199:18 218:9
80:21 204:13 new 8:22 22:8 24:9 nonmetastatic 55:14 220:11 238:19
239:18 24:16 25:11 29:9 57:13 58:19 62:10 271:16 290:8
necrosis 110:22 29:18 56:3,14 65:9 68:6,17 71:1 normally 137:8
111:5 112:8 58:10 59:16 60:9 73:14 85:2 166:17 303:15
need 10:11 18:3 22:7 127:2 148:16 168:9 169:20 norms 21:4
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notable 274:10 154:14,21 239:2 221:14 older 208:18 244:21
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note 35:12 44:6 numerically 218:19 October 61:9 138:12 old-fashioned 194:3
73:16 81:8 86:13 nurse 13:20 181:2 142:7 279:12 OLIVER 9:15
96:3 114:17 119:9 nurses 280:11 287:2 293:19 once 38:1 118:17
119:13 190:8 192:3 nutrition 203:7 285:1ODAC 8:6,8 11:9,9 154:12 155:19
202:11 209:21 nutritional 249:18 12:14,14 14:7 189:9 195:4 207:16
219:3,19 nutritionist 201:11 141:4,5,8,10,19 245:5 285:20
noted 18:4 71:10 249:18 143:18 144:17 287:22 322:18
183:22 229:9 244:8 nutritionists 203:18 156:1,1 180:16 ONCOLOGIC 1:5
283:20 181:11 303:14,14 2:3 3:1
Notes 43:14 O 330:18 oncologist 8:16
Notice 47:7 192:19 O 11:1 12:1 odds 217:20 266:4 147:14 181:7,9,13
213:13 273:6,15 oatmeal 293:17 offer 151:8 284:2 181:15 205:20
noticed 242:22 objective 42:17 office 6:16 7:6,8,12 254:13 312:7
notion 260:2 314:16 142:16 143:4 8:5 15:5,11 17:16 oncologists 28:20
Notre 145:13 149:17 144:21 166:4,6 92:5 95:8 182:11 56:1,2 134:9 165:2
Notwithstanding 167:4,8 241:16,19 183:12 203:22 252:17
88:13 objectively 152:10 officer 6:21 7:21 15:2 oncologist/hematol...
Novartis 142:19 objectives 234:21 184:15 181:17
novel 18:15 29:17 obligate 254:22 offices 91:18 95:1 oncologist’s 148:12
November 107:18 obliterans 221:14 official 8:6 14:7 oncology 2:20 3:20
139:14 141:1,7 observation 32:3 141:8 181:11 4:2 5:14 6:16,19,22
281:7 80:3 Oh 15:22 269:16 7:12,14,19,22 13:20
no-MTP 125:2,6,9 observations 129:18 oil 252:3 253:1 293:2 14:9,11,13,17,18
130:8 213:15 293:3,5 295:18 22:6 29:1 32:13,21
number 26:7 55:4 observe 79:18 106:12 306:13 311:22 34:10 36:15 41:15
71:4 73:16 74:10 observed 42:22 48:5 312:11 50:18 52:22 55:11
74:17 82:2 87:7 64:9 101:13 102:2 oil-mixed 311:16 57:5 62:5 67:5
91:11 92:19 97:9 obtained 17:14 20:11 okay 15:10,15 91:4 70:18 76:5 121:12
113:21 118:17 52:18 83:10 183:10 100:20 103:3 107:6 144:5 146:3,20
125:3 132:9 172:6 199:12 229:18 116:12 119:2 121:4 167:22 181:2
173:8 176:19 230:1 131:7 134:2,3 182:10 186:4 188:8
186:17 191:14 obviated 110:18 135:2 154:10 170:5 209:3 250:6
212:20 218:7 220:4 obviates 112:5 266:5 268:17 ones 119:2 126:13
220:19 239:4,7 obvious 86:15 106:12 274:20 300:1,15,16 242:16 251:17
243:4 252:12 106:14 211:10 300:16 301:15 297:16 315:13
261:22 265:9 obviously 102:10 302:12 303:7 304:9 316:13
268:18 271:14 159:4 188:22 305:8 314:10 329:7 one-third 37:15
297:1 314:1 320:12 210:18 247:20 333:4 39:13
320:13,14 259:18 old 129:12 136:21,21 one-year 234:2
numbers 43:2 61:21 occur 57:8 133:12 277:17 284:14 253:14 263:10,14
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120:11 308:3 274:7 275:11 295:1 34:19 35:2,16 outstanding 124:9
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onset 232:16 237:18 180:17 184:19 39:16 41:13 43:22 26:14 47:16 54:21
open 11:8 12:13 185:2 187:6 189:4 53:5 55:1,15,18 67:14 71:8 72:7
108:21 123:6 189:10,20 224:19 56:12,16,20 57:9 73:2 75:6,19,22
132:18 135:10,12 226:9 238:8 257:19 58:20 59:2 60:2,6 77:7 82:18 83:3,6
135:17,22 147:15 257:22 258:12,17 60:10,14,20 61:2,13 83:14,17,17,19 84:8
261:7 275:5,9 271:1 273:13,16 62:10,18 63:1 89:1,3,5,7,9 93:13
309:21 322:14 284:5 304:2 67:17 68:13 73:4 103:5,11 106:11,13
326:19 order 10:5 11:10 96:21 97:9 98:13 106:15,16 108:8
opened 287:11 13:3 40:1 44:19 99:9 107:15 116:14 110:18 112:4,21
OPENING 276:4 72:11 91:6 95:15 136:22 137:19 113:4,5,8 116:18,20
opens 117:14 147:9 180:12 138:6 143:10,12 122:12 124:8,17
open-label 62:2 69:9 ordinarily 158:5 144:8,12 145:2,12 126:4 129:7 132:15
operating 147:14 organ 196:20 255:17 146:5,13,18,22 132:20,22 154:12
operation 139:12 organisms 221:11 147:2,16,22 148:2,6 160:12 164:12,15
operations 95:4 organization 140:13 149:2 150:2,4,5,9 165:6 171:19
opinion 28:9,19 276:10 150:22 151:13 176:13 178:3,6,10
101:12 124:1 organs 190:18,20 152:22 161:12 178:11 207:11
176:15 orientation 192:9 165:22 166:18 213:12 217:5,16
opinions 156:16 original 46:2 61:4 168:3,4,9 169:20 218:3 230:4 233:1
opportunity 101:22 202:13,14 206:10 175:20 176:18,21 234:3 236:12 263:6
123:13 145:8 211:15 223:7,15 177:1,21 307:13 321:11
152:12,14 153:10 235:8 295:11 ototoxicity 42:22 overcome 112:21
184:18 276:8 278:1 originally 206:8 43:3,4 54:10 101:3 overlap 42:21
283:22 294:3 236:9 101:13 102:2 overlaps 79:15
opposed 126:9 originated 71:5 ought 263:21 overperformed
134:14 156:22 orphan 18:20 21:9 outcome 24:7 25:16 97:18
157:20 216:10 56:12 187:10,15 33:12 35:19 48:22 oversight 35:7
266:21 189:12 190:3,4 49:2 51:12,15,19,21 overview 185:2
opposite 105:9 254:3 199:8 56:13 80:5 88:18 overwhelming
269:3 orthopedic 146:9,10 93:12 119:7 162:6 150:11
optimal 49:10 54:11 146:17,22 147:13 162:7 196:19 206:7 overwhelmingly
option 24:16 278:22 Orthopedics 146:14 223:22 242:9 318:1
291:6 327:4 146:18 outcomes 3:11 Ownership 187:18
options 144:15 326:9 osteogenic 61:18 115:18,20 198:17 owning 17:10 183:5
oral 136:1 185:10 osteomyelitis 150:1 202:19 211:9 o’clock 180:6
186:19 187:7,8 osteopenia 292:1 214:20 223:8 224:3
188:11 189:4 osteosarcoma 18:17 243:5 298:14 P
196:18 197:4 18:17 19:18 20:10 outlined 233:16 P 2:1,1 3:12 38:11
198:21 202:21 21:1,9 23:20 24:6 328:9 39:10 45:4,5,9 46:4
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80:12 81:11,13 pardon 287:22 patent 190:5 48:13,14 49:6,14,16
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207:12 209:21 153:9,10 pathophysiologically 60:11 61:9 62:7,11
210:4 231:20 Park 293:20 294:14 270:12 62:13,17,19,20,21
233:11 Parklawn 17:16 pathophysiology 63:12,14,19,21 64:1
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115:16 172:14 part 16:5 17:12 33:4 patient 5:16 6:10 65:10 66:19 67:16
266:6 271:1 35:8 44:20 93:12 13:18 36:14 37:1 68:2,6,9,10,13,17
packed 149:8 96:9 122:18 129:17 51:14 52:6 65:5 68:19,21 69:1 70:2
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174:14 244:1 267:21 75:22 87:12,17 72:18,20,21 73:3,5
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136:20 279:4 participant 18:2 117:22 122:5,12,18 74:2,7,11,12,13,15
294:20 332:5 183:20 122:21 123:5,7 76:21 77:7,8,18
pain 25:9 87:19 participants 16:9,16 133:22 134:21 81:12 83:20,21
137:3,4,7,8,13,13 18:3,6 182:21 140:19 142:15 84:5,10,12,14,21
147:7 290:17 183:21 184:2 151:17,19 152:5 85:4,6 86:7,8,14,16
painful 283:2 293:6 participate 37:7 163:17 169:19 86:21 87:1,7,14,17
paint 286:6 92:17 139:9 316:19 173:19 181:21 87:22 88:18,21
pairs 50:16 participated 52:20 187:16 196:17 92:1,16,21 100:9
pairwise 47:17,20,22 62:6 147:2 294:14 201:16 204:18 101:15,18,19
48:3,5 98:1 participating 34:20 207:22 218:22 103:19,21 106:6
palatable 253:2 participation 190:9 224:16 227:18 108:19,20 109:1,8
Pam 13:20 particular 24:10 238:9 248:3 249:22 111:1,5 114:17,19
Pamela 2:18 181:2 131:13 154:14 277:4 295:5,7,10 114:20 116:6 118:2
PAM-intestinal 162:8 247:17 297:3 304:2 306:2 119:5,10,11,12,21
197:17 295:12 306:14 314:8 317:4 120:1,6,10,14 121:6
pancreatitis 292:20 particularly 32:1 323:19 328:7 121:8 124:12 125:1
293:6 172:19 193:17 patients 13:9 19:17 125:5,7,9,19 126:11
panel 31:18 52:11 201:21 221:2 19:18 20:10 21:13 129:9 130:2,11,17
panels 316:21 258:13 259:6 21:19 25:8,12,15,21 140:17 141:3
paper 95:6,7 110:3,5 274:10 26:3 27:2,12 28:20 142:14,16,18 143:8
118:13 123:6 141:3 parts 100:3 28:21 29:12 31:10 144:9 145:2 150:6
158:12 159:19 party 265:15 284:14 31:11 32:3 33:9,12 150:15,17,22 151:1
296:13 part-time 282:14 33:16,21 34:4,22,22 152:4,7,8 153:1,2,6
papers 227:20 pass 95:16 121:19 35:3 36:5,9 37:6,14 154:1,14 155:9,10
paperwork 138:20 143:13 177:20 37:15,18 38:2,3,8,9 155:17 161:18,20
paradigm 113:6 298:7 39:5 40:17,19,22 161:21,22 162:21
paradoxic 296:11 passed 122:12 41:2,9 42:13 43:8 168:3,9 172:2,5
paraphrase 163:7 passing 281:16 43:16,17 44:2,3,6 173:17 174:17,18
parcel 308:13 283:16 45:8 46:22,22 174:22 175:20

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176:17 184:17 312:8 314:1 315:19 5:11,16 8:21 9:4 150:10,15 152:8
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195:13,15,22 196:2 327:9,12 330:6 pegging 156:21 201:15 202:5,5,17
196:4,16 198:12 patient-driven penalty 192:2 195:19 202:18 203:2
199:11,17,18,21 276:10 pending 246:17 206:13,14 207:7
200:9,18 201:6 patient-loss 71:12 Pennsylvania 136:19 208:8,9,12,12,19
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208:1,7,9,9,15,17 15:1,3 23:19 24:8,13,16,20 213:6 216:11,21,22
208:18,22 209:1 Paul 8:19 10:17 25:3 27:19 29:6,6 217:6,13,14 218:1
211:19 212:9,12,17 22:11 32:10 163:14 29:11 40:20 118:17 218:18 219:11
212:20 213:9 Pause 294:12 300:7 134:7 152:18 220:6,6,10,10 222:6
215:13,13 216:11 301:17 302:18 163:19 173:6 195:1 222:8,9,11,15 223:4
217:2 218:7,9,10,18 303:6 200:2 211:10,12 227:9,10 228:4,8,8
218:21 220:19,22 pawn 144:9 214:5 220:4,6 228:12 239:5,6
221:15 222:2,13 pay 195:19 221:6 242:8 243:11 248:14 259:10,11
223:9,19 224:13,18 payment 136:6 245:12,15 249:9,14 273:19 289:15
225:4 227:5,9,11,19 275:16 250:4 253:20 298:3 310:13,15
228:3,8,9,12 229:5 pays 308:16 276:15 277:14 313:15,15
229:9 230:20,22 Pazdur 6:14 7:11 283:18 302:20 percentage 150:14
232:18 233:4,20 15:5,5 169:22 307:18 308:3 201:13 212:17
235:8,18 237:20 170:4,7,9 182:11,11 310:13 311:3,16,17 323:2
238:19 239:1,4,7 307:16 308:9,12,17 321:19 324:19 perform 76:1 79:6
241:2,22 244:2,2,14 319:5,7,11,15 329:12 332:9 83:18 89:10 106:17
247:1,3,20 248:2,6 326:19 330:1 331:5 peptide 30:1,4 162:2 332:7
248:20,22 249:1,3 331:17,19 332:1,6 perceived 57:1 performance 80:5
251:3,7,20 252:12 332:14,17 percent 24:12 25:5 90:16 169:11 206:3
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256:16 257:2,4 peak 24:21 34:6 38:8,9,12 39:7 45:20 69:5 75:10
259:4,9 261:19 PEARLMAN 284:9 39:7,11 40:19,21 77:17 80:1,14
262:4,6,9,20 263:22 pediatic 33:8 41:1,2,12 42:12 81:20 82:7,13
264:3,4,11 266:1 pediatric 4:13 8:16 49:15 55:13 57:12 125:22 132:19
267:16 271:13,15 14:18 19:22 21:5 60:10,13 65:2 70:5 133:9 233:15 234:8
271:15 272:7,20 32:13,21,22 34:10 70:6,21 72:17,21 236:11
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298:17 302:16,16 181:1,20 120:1,5,7,10,16 204:5,7 205:6,9,11
302:17 305:18 pediatricians 161:1 124:10 126:4 129:8 205:11 210:19,20
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331:15,16 332:4,7 52:20 53:1,3 54:8 11:6,18 12:9 16:16 227:12 309:12,22
332:15 55:22 56:9 61:19 picked 57:2 120:20 310:4 326:7
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perseverating 314:12 85:19 86:4 97:9 picture 274:5 286:6 46:7 58:16 89:7
persistent 194:13 115:2 121:4,5,9 287:5 317:20 123:16,19 148:16
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person 28:16 167:12 169:12 185:18,22 pills 280:10 281:22 229:15
248:9 186:3 187:12,20 293:2 planned 41:19 45:18
personal 147:1 188:2,14,15,18 pink 51:12 46:6 65:12 83:3
152:11 189:19 203:15 pioneered 56:2 206:10 233:5
personally 28:1 267:18,18 309:18 185:10 235:20
157:13 331:9 309:19 330:4 Pittsburgh 146:9 planning 46:2 309:1
perspective 218:8 phenomenal 330:22 pivotal 34:16 188:2 plans 108:22
315:12 322:3 phenomenon 260:17 188:15 202:8 plateau 269:20
persuasive 170:19 Philadelphia 4:12 203:11,12 208:1 270:11
304:20 13:17 145:15 279:9 215:8 217:20 218:7 platform 203:10
pertain 58:22 283:5 218:11 222:15 platinum 134:14,15
per-patient 86:3,11 Philip 294:9,13 240:15 309:20 play 189:11
86:19 phone 4:17 15:8 310:15 pleasant 292:16
pessimistic 326:3,6 phonetic 139:4 PKHRIKIAN-KY... pleasantly 214:17
PET 99:13,15,21 phosphate 219:7 291:4 please 49:4 89:20
Peter 4:10 13:16 17:9 phosphatidyl 30:2 place 29:9 139:6 99:18 106:18
176:6 58:12 171:18 180:8 272:9 115:12 116:11
pharma 8:14 10:9 photograph 284:12 286:11 332:22 131:8 153:14 155:4
11:16 13:8 136:20 285:12 287:6 placebo 198:18 170:8 178:17,20
145:10 180:17 288:14 289:9 200:11,20 202:5,17 179:17 180:13
184:15 186:6,12 physical 69:11 208:2,10,12 209:10 190:8 240:6 243:19
190:7 244:11 198:14 283:3 209:20 210:3,8,10 261:8 263:18
278:11 328:2,6 289:18 290:10 211:2,6 212:2,7 290:18 299:20
Pharmaceuticals physician 74:4 87:13 213:5,9,20 215:13 300:4,6,20 303:12
186:10 187:19 116:6,10 137:15 215:13 216:22 311:13 318:9,13,15
190:6 138:5,6 140:3 217:1,14 218:13,20 329:20 331:21
pharmacies 296:2 149:18 151:21 218:22 219:12,14 332:19
Pharmacology 4:11 201:16 215:16 220:6,20,21 221:4,9 pleased 22:5

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pleasure 23:18 77:14 78:4,15,21 330:3 33:7 57:8 146:5
plot 39:2,21 148:20 80:5,9,12,16,19 possible 45:13 47:13 168:16,22 172:2,10
209:19 210:15 81:10,10 82:13 47:17 51:10 54:10 183:1 193:5 234:1
213:16 88:3,7,13,22 97:12 66:3 78:10 89:21 238:9 246:6 265:5
plus 36:1 64:11,13 97:14 110:12 139:3 147:20 240:8 320:17 327:4
90:19,20 102:3 117:22 127:10 264:15 290:17 potentially 141:11
111:8 114:12,12 156:9 158:2 160:19 possibly 219:15 167:8 225:6 294:18
159:10 200:10,11 171:18 217:19 288:4 pounds 279:18 286:3
222:3 327:8 pooling 65:18 117:16 post 213:3 215:19 289:4
PMS 286:21 127:11 226:3 230:7 224:3 230:4 236:12 powder 295:22
pneumonia 221:14 230:8 234:11 267:22 268:4 289:6 power 153:13 206:13
podium 84:15 235:22 236:21 postoperative 148:7 218:4 260:18,19
POG 61:21 62:5,11 237:1 postpone 306:1 279:21 320:5,11,12
68:1 78:5 Pooling/meta-anal... postsurgical 63:7 320:13,15 323:15
point 89:20 110:20 238:1 postulated 258:16 powered 36:11 65:8
131:13 134:4 137:7 poor 90:16,20 post-hoc 83:5 144:2 66:8 67:12 109:20
148:22 149:4 151:8 population 21:17 168:15 171:3 110:8,9 112:2,18,20
157:8,21 208:13 25:18 37:18 41:5 207:18 226:2 230:3 115:22
213:22 220:10,14 44:1 68:18,20 232:10 233:10,15 powerful 151:12
227:4 240:7 245:22 99:14 160:2,13 233:16 234:4,8 PowerPoint 19:9
246:8,20 247:17 187:16 224:18 236:11,17 305:4 23:16 29:15 32:8
248:4 253:19 257:1 226:22 227:4,14 post-occurrence 44:14 52:9 58:8
258:20 260:3,6,7 235:16 304:3 176:21 75:1 84:18 91:22
262:3 263:7 266:7 320:16 321:14,21 post-one-year 243:5 101:11 120:4
268:11 278:9 280:9 323:19 328:8 245:17 125:17 127:9 130:5
286:3 293:9 306:2 populations 21:9 post-randomization 156:4 171:20
306:14 307:12 62:9 85:2 226:20 189:3 213:3 217:22 184:11 189:22
308:14 310:5 227:18 230:14 223:3 230:4 233:1 225:18 231:8 244:9
316:18 317:8,15 235:13 233:2,8 234:3 250:18 258:2
319:20 323:18 portion 299:1 243:14 245:8,9 259:22 262:17
328:22 331:3 pose 102:14 245:5 post-recurrence 263:19 272:2
pointed 162:3 204:17 261:13 155:18 177:5 294:10 325:5
234:14 235:14 posed 167:19 179:20 post-study 233:21 practical 204:7
251:3 330:1 180:3 post-transplant 309:14,16 310:1
pointer 297:6 position 190:8 206:5 208:8 213:3 327:21
pointing 103:17 306:20 222:16 223:5 practicality 324:1
points 236:4 249:17 positive 22:21 51:7 226:18 229:19 practically 320:7
316:15 320:3 331:6 51:13,15,20 113:10 232:12 237:15 practice 27:13 56:4
331:12 160:11 236:7 288:5 296:18 134:16 228:9
policy 140:15 242:12 312:17 post-treatment 34:7 248:17 312:2
political 138:20 317:10 post-treatments practices 36:16
144:10,13 possibilities 118:22 233:21 practitioner 134:16
pool 85:1 105:4,8,13 possibility 120:19 potent 186:14 202:1 prayed 149:15
107:6 119:12 143:20 171:2 273:4,9 274:4 152:14
pooled 65:13 75:8,14 270:15 305:3 309:4 potential 16:11 20:9 prayer 150:9

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prayers 284:3 205:21 135:20 156:4 pretransplant
preamble 170:4 preexisting 259:7,16 171:20 184:9,11 284:13
prechemotherapeu... preface 157:4 185:3 188:12 pretty 107:14 158:7
150:8 prefer 297:20 189:15,22 225:17 158:15 291:11
precious 283:9 preference 118:1 225:19 230:6,12 292:15 329:16
precision 113:12 preferred 178:2 231:8 232:12 prevent 195:4 242:8
preclinical 19:3 premalignant 67:22 234:14 235:15 prevention 151:6
52:16 premature 213:19 237:3 238:5 240:19 313:4
preclude 16:5 136:14 premise 223:15 240:20 244:9 previous 18:8 68:1
182:17 276:2 preparation 21:22 250:18 258:2 79:17 113:21 184:4
precluded 151:17 45:1 172:13 259:22 262:17 208:4 217:21 222:8
preconceptions 28:7 preparations 228:22 263:19 272:2 275:8 248:17 323:9
177:14 preparative 253:22 294:10 325:5 previously 28:6,8
predict 124:12 256:4 presentations 15:21 43:20 47:12 215:21
predictable 148:2 prepare 148:18 28:7 60:5 90:1 278:12 331:19
predicts 196:19,21 prepared 19:13 191:15 239:22 primarily 24:19
prednisolone 12:3 152:11 165:2 278:12 260:14 276:15
225:1 202:13 presented 53:2 74:20 296:15 298:16
prednisone 12:3 preparing 20:6 41:22 123:4 124:2 132:22 primary 21:17 25:1,5
189:7 192:6 193:5 preponderance 39:2 161:3 231:10 232:1 25:10 33:1 34:21
193:22 194:20 39:22 232:11 237:2 35:6 36:5,9,10
195:2,14,16,17,20 Prerequisites 236:5 247:18 317:7 37:12,13,14 38:5
195:20 196:2,5,6,11 prescribe 98:20 325:16 331:13 40:12 45:3,11,18
196:12,17 197:2 prescribed 137:10 presenter 185:4 46:5 52:2 54:20
198:8,9,11,13,15 149:19 presenters 265:8 67:9,14 70:22
200:1,10,11,13,15 presence 41:17 95:13 275:1 329:14 75:20 76:10 82:18
200:19 201:4,5,8 151:22 176:13 presenting 58:10,14 82:20,22 84:8
205:7,9,19,22 211:1 177:2 presently 146:8 88:14 102:17 124:4
211:20,22 215:17 present 9:6 16:11 presents 73:10 150:6 156:11
217:3 221:6 222:3 22:3 25:8,12 98:13 169:19 312:3 177:10 184:20
223:8,18,20 224:1,7 105:16 129:1 preservation 198:10 188:18 201:9 202:4
224:8,11,13,14,22 150:18 183:1 preserve 314:17 205:14 207:1,5,12
229:6,10 241:3 184:18 185:5 president 4:5 184:14 209:8,17 214:14
246:22 247:3,4,5,8 225:21 231:5 328:2 226:14 227:13
247:10 250:4 266:3 presentation 10:8 prespecified 83:3 229:14,20 231:14
273:7,11,14,17,18 11:3,15 12:5 15:18 89:5 230:16 232:3 231:16,18,19 232:2
273:22 274:1 18:13,14 19:9 233:2 237:10 232:8 233:12,14,18
277:11 280:1,6,13 23:16 29:15 30:15 268:13 234:21 236:17
286:16 291:21 32:8 35:11 44:14 pressure 285:21 237:6,7 239:14
292:7 298:10 52:9 58:4,6,8,17 315:20 240:12,20 242:10
310:14,16,18,19,21 62:1 70:14 75:1,2 pressures 315:19 242:18 245:6
311:1 325:10 77:9 84:18 91:22 presumably 118:8 251:17 264:22
prednisone-inducti... 96:22 101:8,11 221:13 314:4 265:16 267:3 272:4
210:2 120:4 125:17 presumed 170:22 322:2 328:10
predominantly 126:19 127:9 130:5 305:1 330:21

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principal 32:12 303:6 84:18 91:22 101:11 78:10 108:3 114:10
52:22 process 69:8 112:14 120:4 125:17 127:9 144:21 180:16
principally 25:4 122:21 135:15 130:5 156:4 171:20 187:6 189:4 224:19
principle 51:6 247:9 142:5 171:13 184:11 189:22 226:10 304:2
prior 63:15 64:3,6 194:17,17 199:16 225:19 231:8 241:7 prospective 36:2
67:18 74:2 84:7 200:17 269:9 275:3 244:9 250:18 258:2 62:2
87:9,14 113:22 279:1 289:3 259:22 262:17 prospectively 59:18
171:5 173:19 processes 197:9 263:19 272:2 227:3 236:3 241:20
174:10 207:1 248:8 produce 108:16 294:10 309:2,4 268:2
305:6 313:16 product 10:14 19:1 325:5 protect 290:22
private 139:2 20:2,20 22:10 progressed 151:11 protected 311:1
privilege 18:22 29:14 30:16 108:12 progression 49:17 protection 242:7
276:20 108:13,16,18 136:3 progression-free 244:3
probability 38:7 141:14 144:1 34:1 178:1 protein 64:16
probably 53:11 73:7 186:13,20 252:7 progressive 195:2 protein-binding
84:14 98:6 108:22 275:13 311:16 project 18:22 274:3
124:12 125:11 328:18 projectile 285:3 protocol 20:13 36:12
142:8 158:18 159:9 products 6:16,19,22 prolonged 197:3 36:13 42:9 44:19
171:17 173:6 7:12,14,19,22 18:1 198:15 274:18 49:6,12,15,17,18,22
246:11 252:1 18:9 144:5 182:10 277:19 280:17 50:4,18 61:20
257:17 271:21 183:19 184:5 188:5 282:19 283:8 64:13 67:10,12
285:13 291:16 190:4 199:8 204:16 promising 33:4 70:6 74:16,19
293:14 305:19 professional 152:11 prompt 96:6 325:20 81:19 82:4,5 87:9
306:4,6 308:9 professor 2:7 3:5,15 prone 282:16 96:17 101:15 104:4
317:12 320:6,10 4:6,15 5:2,7,11 9:4 proof 247:9 108:7 113:14 115:4
322:4 326:2 52:12,15 185:7 propensity 32:2 126:1 148:10
problem 69:22 70:10 profile 22:21 54:3 proper 41:19 96:6 149:20 171:6 188:3
72:8 73:8 90:14 188:20 271:20 307:6 199:9 201:6 202:14
129:17 134:12 310:6 329:4 properties 30:4 205:4 236:3 288:12
160:3 164:11 165:1 profoundly 214:13 186:16 305:7
212:11 214:2 217:2 prophylactic 328:21 protocols 26:18
280:14 301:10 progenitor 208:21 prophylaxis 191:20 protocol-specified
problematic 160:8 prognosis 150:20 192:13 193:14 69:15 73:17 74:9
problems 70:12 89:2 196:21 201:1 205:12 74:18 85:15 89:6
131:12 159:6 170:5 prognostic 38:20 326:10,13,14,18 protracted 224:6
233:16 282:10 Prognostically 327:3,5,14 protuberans 142:11
procedure 78:21 147:20 propionic 273:2 prove 60:2 317:4
225:6 program 51:1 140:19 proportion 72:11 proved 111:20
procedures 36:20 143:12 146:1 74:7 88:20 111:4 307:12,13 310:22
230:17 185:15 187:11,20 203:2 216:21 311:5
proceed 301:21 294:14 308:20,22 226:16 230:20,22 proven 111:17 313:7
303:10,20 progress 19:9 23:16 238:22 Provenge 144:7
proceeded 104:19 27:21 29:15 32:8 propose 141:17 provide 29:9 40:1
proceedings 300:7 39:15 41:13 44:14 223:16 225:10 42:3 51:13 52:5
301:17 302:18 52:9 58:8 75:1 proposed 61:10 66:3 59:10 114:14

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118:10 213:1 236:6 pull-up 285:4 289:6 128:3,12,13,16 253:12 254:11
327:12 pulmonary 25:22 156:19,21 215:8 264:13,14,16 265:7
provided 37:10,11 26:3 31:11 32:2 quality 59:5 70:12 268:9,13 269:7
38:6 40:8,12 82:6 33:16 69:17 147:19 72:8 90:21 92:6,13 293:2 300:8 301:9
94:2,4 132:5 150:11,15 151:2,7 95:16,18,22 96:7 302:1,1,4,5 303:21
140:18 145:9 151:19 152:2 117:17 121:19 304:4 305:10
170:15 203:10 154:15,18,21 122:9,12 310:12 311:13
228:21 304:16 155:13 190:22 quantitating 241:16 317:17,20 318:9
provides 41:6 44:8 pulmonology 200:13 quantitative 46:17 324:11 325:6
51:18 52:6 55:9 pulpit 332:10 47:4 104:7,12,14 330:13
59:19 140:14 pun 287:22 105:12,21 106:7,20 questioned 112:20
170:18 276:14,14 purpose 232:20 107:3,4,5 126:22 questions 11:7,9
304:19 236:2 237:16 127:5,13 128:3,12 12:12,14 15:21
providing 185:1 purposes 195:4 156:19 21:8 23:5,8 35:9
proximal 25:7 pursue 153:7 quantities 251:7 89:13,14,21 90:5,6
proximate 212:7 push 286:12 271:11 91:5 99:7 103:6
264:22 put 95:12 115:16 quarter 271:15 105:19 107:13
PRs 297:9 137:15 156:3 173:2 queries 123:7 112:18 117:14,18
psychosocial 329:13 198:6 205:2 242:5 query 122:1,20 126:16,18 131:8
329:15 248:14 272:9 278:6 question 35:10,18,20 134:20,22 155:7
public 11:8 12:13 281:4 285:17,18 65:6 66:8 89:16 156:1 162:14 169:8
15:11 16:1 135:10 292:19 293:1 295:5 91:7 96:9,13 98:9 169:18 171:11
135:12,15,17,22 295:7,19 309:16 100:20 102:14,21 240:1,4,7,9 247:14
140:15 142:20 312:20 318:9 328:3 103:4,13,13,14 257:11 261:1,12
144:3,7 153:19 330:2 104:6 106:10 267:11 303:12,14
261:3,7,14 274:21 putative 50:19,21 107:14,17 109:12 308:2 318:6 329:8
274:22 275:2,5,10 51:3,9,11 113:7 112:5 114:4,7,16 330:11,12
276:4 299:1 329:13 114:2 115:5,11 118:6 quick 90:9 133:15
330:19 331:5 332:7 putatively 154:17 120:18 121:14 261:5
332:8 putting 106:13 123:16 129:4 quickly 147:21
publication 70:19 puzzled 258:15 133:15,15 154:5,7 283:21
102:15 103:18,19 pylorus 194:15 155:5,7,17 156:3,6 quite 117:13 127:15
105:2,17 P-R-O-C-E-E-D-I-... 157:4 160:22 161:1 150:17 168:6,10
publications 176:19 13:1 161:12 162:4,5,8,11 174:7 240:22
309:18 p.m 1:8 180:7,9,11 162:15,20 167:19 245:13 252:11
published 26:22 34:2 333:6 168:6 171:15 253:3 271:3 293:6
43:20 52:21 53:7 P450 273:2 172:22 173:5 311:7 321:3 328:6
68:4 76:4 102:22 174:13 175:16 329:14
103:7 107:19 Q 176:7 178:17 quote 109:12
146:14 164:2 qualified 145:11 179:20,22 180:3 quoted 129:13
227:21 294:22 qualify 255:18 211:20 240:11 quoting 110:6
309:10 qualitative 46:13 241:17 242:5 Quynh 136:18
puke 285:2 47:5 104:7,12 244:12 245:5 Q-and-A 185:17
pull 286:18 287:9 105:7,21 106:7,21 246:17 247:15 240:16
pulled 221:10 106:22 107:5,10 251:22 252:5
126:22 127:5,14,18 R

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R 2:1 217:18,21 222:9,14 rationale 60:4 196:18 305:21 308:12
race 38:19 223:9 225:22 254:5 258:11 313:17 316:11
radiation 68:1 226:11 227:12 ratios 38:22 328:15,17
290:12 309:19,20 312:6 rattle 90:8 Reaman 5:10 14:16
radiation-induced 316:22 324:14,14 ravages 290:22 14:16 112:16,17,17
67:22 randomized-contr... ravaging 279:15 114:4 115:6,8
Radiographs 25:9 29:2 reach 116:20 272:21 165:16,19 178:20
radiotherapy 25:20 randomly 27:1 323:13 179:4,4
rages 286:17 110:21 reached 27:11 75:13 reap 257:17
raise 126:17 330:12 range 24:22 296:19 81:9 165:14 272:11 reason 74:2 87:11
raised 45:2 118:16 296:21 reaching 280:2 111:6 126:8 130:20
247:17 315:13 ranged 37:20 reactions 87:19 135:21 159:16
raises 164:6 ranges 315:22 316:5 138:17 215:12 259:15
Rajeshuari 8:1 182:3 rapid 130:22 229:6 read 15:22 135:12 275:9 283:17
Ralph 5:1 14:14 rapidly 30:19 200:19 170:5,7 182:13 reasonable 269:10
ramification 69:6 274:13 186:9 274:22 295:14
ran 53:3 283:4 rare 18:19 25:2 reading 108:5 207:9 reasons 20:8 49:22
288:19 140:17 141:3,14,18 252:2 73:22 87:17 91:11
random 102:4,6 142:10 143:1,5,10 readings 148:20 100:11 169:11
112:8 172:7 174:4 144:19 219:20 readmitted 279:12 234:12 310:2
259:18 242:13 316:20 readout 313:3,4 reassemble 180:5
randomization 8:7 rarely 28:22 56:3 real 24:15 159:6 recall 77:18 217:8
38:2 45:14 49:8,10 rarity 57:20 142:21 164:10 225:4 Recalling 280:19
49:12 63:7 168:12 143:16 145:1 271:18 282:2 289:3 receipt 91:17 92:3,4
205:7 206:16 212:4 rate 28:12 55:13 320:1 receive 27:2,4 38:3,9
212:18 213:1,4,7 82:10 83:1 130:22 realistic 143:20 39:5 40:17 41:10
215:20 218:2 224:4 155:13 207:11 realities 144:19 44:7 45:17 48:14
228:13 230:5 210:10,10 232:9 reality 141:12 265:10 64:17 74:8,9,12
232:15 236:13 233:13 234:7 237:8 realize 317:9 86:9 87:2 94:19
243:6 244:19 245:2 237:11,14 realized 143:2 98:22 101:16 111:2
248:9 324:13 rates 134:10,11 really 89:22 113:9 152:19 155:10
randomized 24:5 202:22 206:2 263:1 116:13 117:2 127:3 284:17
26:8,20 39:5 41:10 315:10 128:18 134:12 received 33:10 38:4,8
45:9 46:22 48:13 ratio 38:11 39:10 139:22 157:15,15 45:16 50:12 55:1
48:14 50:11 57:17 41:10 45:10 46:21 160:14 162:7 63:12,14,20 64:2
61:2 62:3,22 63:14 47:2,4,12 48:18,20 165:12 168:6 70:4,5,6 74:14,16
64:2,22 65:3,5 69:9 48:21 79:2,5,22 172:20 173:5 85:8 95:9 101:18
74:8,11,15 77:19 80:10 81:11 126:3 177:13 220:16 101:20 111:1
85:1,6,7,8 86:9 126:5,7 131:17,19 225:10 242:19 113:19 123:12
87:2 109:5,7 111:1 160:12 209:14,22 243:3 254:3,8,15 146:16 147:15
187:13 188:13 210:11 215:22 257:5,15 259:5 149:19 152:1,16
190:13 191:19 216:4,7,7 217:20 260:17 265:19 187:15 190:6 200:3
198:18,20 199:6 218:1 223:15 266:16 267:10 219:1 227:9 244:15
200:9 208:1 209:2 224:17 260:8 263:3 269:19 270:6 279:4 248:4 251:7 257:3
212:12,21 215:7 320:20,22 321:2 279:6 280:9 283:12 262:21,22 278:10

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297:4 recurred 31:15 122:5 refused 87:18 80:22 81:3 97:15
receives 16:18,22 148:9 161:18 regain 282:4 283:10 112:10 193:9,11
17:3 151:18 recurrence 32:19 regard 113:3,4 161:7 228:13,17 230:21
receiving 49:6 50:8 110:17 131:2 155:8 203:13 304:7 235:17 243:2,12
86:14 167:10 207:3 155:9,11,21 176:18 305:10 310:6 321:7 255:13,14,15 311:7
230:20 231:1 177:1,3,5,6 328:12 311:14
232:19 237:21 recurrent 33:16 regarded 46:12 regiment 310:18
251:8 252:14 205:16 215:14 51:16 104:18 regimen’s 216:20
receptor 274:3 recused 190:8 138:19 registered 62:8,14,20
receptor-binding reduced 191:13 regarding 13:8 62:15 261:6 279:6 299:3
273:6 193:10,18 211:20 228:22 231:11 299:6,11
recess 135:9 180:7 255:14 262:2,8 235:22 237:1 registration 67:19
261:10 293:12,13 247:19 84:8 237:4 239:14
recipes 205:21 reducing 28:12 regimen 35:13,14 regulated 16:10
recipients 191:6 reduction 21:12 42:20,20 46:16,22 182:22
recognize 207:9 39:13 41:11 206:14 47:1 48:20,21 regulatory 9:18
288:19 322:12 209:15 210:11 60:22 61:1 63:4,4,9 17:12 44:16,20
recognized 195:7 213:6 218:1 222:7 63:12,13,17,19,22 52:3 58:21 61:3
recognizing 317:21 222:8,10,11,15 64:1,2 65:15,16 157:20 159:2,22
recommend 116:17 223:4 263:15 66:14,14,19,21,22 163:6 183:9
153:14 167:16 313:14,15 67:1,2 73:19,21 reinitiate 108:14
245:18 reductions 188:21 75:9 77:15,19 78:2 reiterate 134:11
recommendation 222:4,14 297:11 78:3,18,18,19,19 224:19 246:19
141:8 161:14 reemphasize 317:8 79:7,11,12,13,17,18 307:16
245:11 refer 61:22 226:1 79:20,21,21 80:1,1 relapse 21:12 32:17
recommendations reference 114:2 80:5,6,8,8,13,14,16 38:7 55:4 69:18,19
142:5 252:16 referenced 295:11 80:18,18,20 81:1,4 69:21 72:14,16,19
recommended 114:8 referred 58:12 96:10 81:7 88:5,9 96:15 76:14 88:21 93:5
114:14 115:1 139:2 96:17 99:3,4 96:3 100:9 109:8
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record 16:5 18:5 305:6 111:7,15 112:1,8 265:1,2 267:16,17
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125:7 178:22 reflection 194:16 227:8,10 229:13 relapse-free 26:14
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records 37:1 122:19 reflects 54:3 79:16 237:19,22 243:7 related 23:9 85:20
123:4,9,16 99:8 170:13 304:14 245:18,20 253:22 96:10 143:15
recoup 57:1 307:20 refractoriness 270:6 255:10 256:4 257:3 146:14 196:16
recovery 140:4 177:7 refractory 151:3 314:3,14 321:16 201:20 202:19
195:5 308:20 254:19 296:4 regimens 26:21 45:9 212:15 219:6,15
recur 151:15 refugee 138:20 48:19 65:11 66:12 264:21

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relates 90:1 114:8 149:9 198:13 316:8 13:15 16:11 24:1
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136:13 276:1 remission 139:16 260:13 252:11 290:16
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relevance 56:16 replaced 193:10 210:6 213:16 323:1 residency 146:10
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reliable 59:21 170:18 report 20:7,14 37:2 213:17 residual 288:7
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relied 203:22 70:22 76:10,12,12 321:1,2 resource 328:4
relief 280:14 287:4 76:16 77:1,2,5 required 59:16 60:2 respect 18:6 41:16
relieve 280:3 90:21 91:13,17 70:1 122:6 201:17 93:13 104:20
reliving 133:14 92:4,21 94:15,17,18 206:13 227:19 128:11 160:16
reluctantly 147:9 95:12,13 118:7,9,10 248:9 310:14,15,19 171:22 184:2 237:6
remainder 58:13 122:8,15,17 141:3,6 requirement 141:18 243:1 246:1 251:16
70:14 142:15 200:7,8 170:12 304:13 315:14 316:2
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31:4 33:4 34:3 39:3 reviewer 7:5 8:4 57:22 320:21 321:1,3
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52:21 53:7 58:18 226:5 RN 2:18 11:14 ruled 204:7
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SAEs 218:14,14 scanning 100:4 63:6 64:12 69:8 269:20,20,21 270:2
safe 19:19 298:12,17 scans 149:21 72:8 75:12,21 76:6 270:7 281:9,13
safely 197:5 scared 282:6 286:11 83:16 93:14 96:9 288:14 296:16
safety 12:10 16:17,21 Schaber 11:18 184:8 100:20 107:17 297:3,10,13 313:12
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74:6 84:16,17,20,20 330:1 122:13,15 150:7 seeing 102:3 246:1
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198:22 202:2,19 195:11,13 176:11 180:6 217:7 270:10
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223:9 224:9 226:7 schema 115:2 200:4 secondaries 25:22 seemingly 96:5
226:17 229:19 205:5 secondary 45:7 67:9 seen 21:16,18 22:14
232:13 238:6,15 scheme 48:3 205:6 113:4 128:5 156:12 27:21 28:6 39:4
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salad 295:20,20 182:5,5 225:16,20 206:1 207:15,17 55:7,12 64:12
saline 30:9 225:21 231:9,13 210:5 226:15 66:16 71:15 100:12
salvage 155:13 232:1,11 234:14 265:10 268:9 121:7 133:17
sample 62:15 206:11 235:1,14 238:4,7 321:11 322:1 147:13 177:22
266:22 239:20 256:22 Secondly 110:11 205:5 246:3,12
San 14:5 181:9 257:1 265:13,21 119:14,19 234:18 255:21 258:21
sarcoma 13:9 24:2 267:1 secretary 8:8 163:7 264:9 278:12 312:8
61:18 67:22 140:13 Scholars 146:1 331:20 313:17 328:15
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sarcomas 115:12 science 146:11 281:5 secure 332:11 seizures 285:17
sat 137:2 Sciences 5:13 security 302:21 selected 30:8 37:1
satisfied 142:3 scientific 4:19 157:20 331:17 332:12 83:12 148:20
save 55:19 138:7 168:1 169:7 305:15 see 81:5 91:3 93:11 322:16
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saw 28:5 147:11 151:21 123:9 130:7 132:21 119:16
161:7 177:17 score 206:3 216:13 139:4,22 163:22 self-worth 279:20
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saying 128:7,18 263:22 174:16 194:16,16 send 96:6
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289:1 205:6 244:22 247:17 306:15
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scam 302:19 seats 180:14 259:5,14,15 260:9 100:10 117:13
scan 69:16 147:18 Seattle 252:5 260:14,16 262:5,22 sensitivity 46:10 80:4
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125:13,19 128:19 seven 62:7 68:19 97:3,22 98:1 54:14 55:21 56:8
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173:19 174:9 76:21 81:12 118:19 151:13 159:15 286:1 291:20 298:9
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sensoring 129:18 319:4 327:12 270:20 signal 50:13 101:2
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sensory 172:11 seventies 256:15 56:18 97:14 178:11 signals 51:11 214:11
sent 93:22 331:22 seventy 130:18 215:9 248:18 259:3 signed 67:20
separate 79:1 119:7 seventy-eight 62:13 269:2 284:11 significance 46:1,9
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separately 78:20 192:6 193:6 195:9 27:14 31:12 33:13 significant 21:11
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230:18 284:1 285:3,4,16 43:20 49:19 50:1 39:6,9,15 41:12
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set 71:14 102:11 212:13 213:2 178:1 245:16 194:17 197:12
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sets 50:16 261:22 263:22 sideburns 285:9 227:1 228:2,17
setting 144:22 158:22 297:5 313:14 side-effect 271:20 245:1 264:6 311:20
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similarity 48:17 155:14,16 215:16 297:17 sorts 216:2
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simpler 307:9 149:19 219:14 22:12 32:11 216:9 228:6,7,14
simplistic 260:13 281:21 288:1,7 slopped 287:13 231:2 244:18
simply 241:20 251:12 296:14 297:9 slow 195:2 259:10
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simultaneous 151:12 sixty-four 62:6 109:7 142:9 151:16 spacer 30:1
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single 33:10 58:18 Sixty-seven 208:1 194:6,18 212:20 speak 52:7 145:8,12
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315:20 sized 36:11 smart 163:19 speaker 135:22
single-agent 43:4 skeletal-looking smile 287:4 136:16 140:10
single-arm 84:21 281:14 soft 25:11 325:18 145:5 275:10 276:5
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single-center 188:14 199:17 206:20 solution 284:5 speakers 19:1 153:19
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single-institutional skin-like 287:14 somewhat 160:11 speaking 136:14
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single-site 227:11 sleeping 280:14 son 284:11 special 141:11 188:3
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sit 164:7 299:20 119:17 126:19 269:14,16 285:14 221:11 249:16
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309:1 319:17 321:7 112:12,13 116:13 states 55:20 98:9 step 28:11 116:2
Sponsors 19:5 135:4 130:13,20 134:12 138:21 161:16 Stephen 5:6
136:6 159:9,10,13 161:16 236:1,4 238:7 steps 20:17

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stepwise 34:13 67:11 125:18 118:12 130:21 168:12,14 169:12
steroid 202:1 211:11 strata 210:13 212:4 155:12 166:13 169:15,17,17
220:3 250:12 253:8 213:8 169:6,10 170:11 170:17,17 171:1
263:16 296:11,20 strategy 200:1,12 188:10 196:10 185:19,22,22 186:3
297:11,15 314:18 stratification 209:17 197:16 198:1 187:14 188:5,6,13
steroids 200:3 228:15 235:2,3,5 248:7 208:14 228:20 188:15,15 194:4
239:11 244:4 250:2 249:14 232:5 235:12 236:7 196:1 198:20 199:7
250:11 251:7 262:2 stratified 78:21 236:9,22 238:2,3 201:9,10,11,19,20
262:10 277:12,13 125:22 206:16 239:17 248:17 202:16,17 205:2,3
277:14,20 280:1 207:2,7 209:16 270:19 272:18 205:12,15 206:16
282:15,19 284:4 217:5,16 228:14,15 298:12 304:12 207:18 209:1,9,12
291:19 294:16,17 231:20 265:2 309:2,3,4,7 313:13 210:7 211:1,6
296:9 297:8,17 321:19 324:20 330:5,7 218:15 219:1 220:5
298:14 310:5,7 stratify 227:2 267:14 study 19:6,21 20:2,7 222:6,7,8 223:4
329:1,3 321:18 20:12,14 21:2,4,10 225:22 226:1,11,17
steroid-sparing straws 281:2 21:15 22:1,3,14 226:20,22 227:8,19
295:15 296:11 strength 282:4 24:2 31:14 32:6 228:2,9,13,17,18
311:6 289:19 33:3,9 34:12,15,16 229:10,12,16
Steve 160:5,19 stress 91:9 278:5 34:19 35:8 36:2,4 231:14 232:4,4,7,15
300:13 stressful 286:20 36:11,12,22 37:1,17 233:10,12,16 234:9
Steven 16:20 strikes 289:20 40:6 42:6,8 43:1,7 234:14,16,18,19,19
Stevie 280:21 striking 243:3 43:7,12 44:16,18 234:20,20,21 235:4
Stewart 276:6,8,9 283:14 49:9 51:19 54:8 235:4,6,11 236:13
stim 298:4 strong 41:6 52:5 55:7 56:10 57:17 236:14,16 237:4,6,7
stimulated 330:13 59:21 138:16 166:5 60:22 61:19,19 237:8 238:15
stimulates 29:22 186:15 245:9 62:3,7,12 64:22 239:14 240:12
stock 17:6,10 53:14 stronger 264:7 65:21 66:4,5,7 67:4 244:5 247:19
53:15 183:6 strongest 274:17 67:6,12,19 68:5,22 248:13 249:18
stolen 200:13 319:20 320:2 322:4 69:9 75:3,20 77:18 250:1,21,21 251:14
stomach 194:5,15 strongly 223:22 77:19 78:4,6,11,12 257:3 258:21,22
279:15 284:1 224:17 80:21 82:18,21 259:13 262:20
stood 137:2 structure 60:4 83:13 85:3 89:4 265:2 266:20 267:1
stool 199:15 struggle 164:12 92:16,19 93:16 267:2 271:16
stop 134:19 280:4 283:19 95:6 96:5 98:16 294:15,18 295:6
281:3 struggled 280:10 99:4,16,20,22 304:18,18,22 305:2
stopped 249:3 struggling 164:17 103:20 104:17 313:9 314:9 319:6
stopping 164:6 249:6 107:18 108:19,21 319:14 320:3,6,12
204:20 stuck 317:18 109:2,20 110:8 320:17 321:6
storm 144:3 studied 62:9 168:4 111:18 112:2,18 322:13,13,13,15,17
story 150:17 189:10 307:18 115:2,21 117:10,13 322:18,20,21
242:19 245:15 studies 19:15 31:21 118:18 119:15 323:20 324:2
287:7 291:5 292:22 33:6 34:8 37:6,7 121:4,6,9 122:3,6,8 325:18 328:4,21
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subject 21:21 41:21 subtype 142:10 143:1 230:11 231:4,9 26:2,10,17 33:10
176:8 143:3 268:7,8 53:21 60:14,16
subjective 42:17 success 201:14 211:6 superimposed 67:1 63:12,19 146:9,10
subjects 129:18 successes 211:5,12 superimposes 97:16 148:6,15 151:4,17
259:11 211:14,19 220:11 superior 310:6 311:2 155:21 176:22
submission 20:21 successful 149:16 314:17 surgical 60:17 61:13
40:9 44:16,20 45:1 258:14 290:16 superiority 81:6 63:2 65:1 149:22
68:16 94:21 103:19 succumbed 283:14 supervisors 331:21 155:18 177:7
114:22 succumbing 256:21 supplement 142:20 surliness 280:17
submit 41:22 Sue 276:6 supplemental 214:10 surprised 172:12,14
submitted 16:7 20:13 suffer 23:20 supplementary 71:6 214:17
58:17 59:5 61:8,10 suffice 141:12 supplied 59:8 surprising 266:14
61:15 70:13,16 sufficient 59:19 support 39:20 41:7 330:22
71:2,6 72:9 73:9 160:1 236:6 271:12 52:19 59:6,16 60:1 surrogate 50:19,21
76:7,18 88:16 sufficiently 112:19 61:8,15 70:13 89:2 51:3,9,11 100:13
92:10 93:18,20,22 suggest 31:21 43:14 140:19 187:10 113:7 114:3 178:7
94:7,15 95:8 122:2 239:21 263:9 276:15 328:4 surrogates 33:1
122:7 142:19 329:10,17 supported 33:18 surrounding 141:2
155:18 182:19 suggested 137:20 38:17 surveys 27:17
234:10 304:1 suggesting 217:1 supporting 60:3 73:3 survival 18:16 20:16
submitting 17:15 suggestion 49:2 76:16 123:12 21:18 22:2 24:11
183:11 166:6 176:16 242:15,19 24:17 25:18 26:1,5
subsequent 51:4 64:8 324:21 328:20 supportive 21:13 26:9,14 27:5,6,10
118:3 121:5 144:7 suggestions 321:6 230:17 234:16 27:12,16 32:16
233:5 234:2,6 suggestive 213:7 supports 223:17 33:2,2 34:5 36:8,8
235:20 237:9 suggests 175:15 242:9 36:10,13,19 39:4,6
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subset 38:17,18 39:3 suited 32:1 295:20 41:3,7,8,18 42:5
39:20,22 50:10 Sullivan 186:4 suppress 220:1 43:19 44:6,10
257:2 254:10,12,12 255:4 285:15 48:11,22 49:1,5
subsidiary 172:22 311:10 312:10 suppression 193:7 50:3,17,19,20 51:5
186:12 328:13 220:4,17 223:13 51:9,12,13,15,20,22
substantial 24:9 summarize 226:8 238:16,17 239:1 52:5 54:1,6,18,21
28:11 59:11,13 237:3 sure 98:17 111:19 55:10,13 57:12,14
170:2,9,15 171:8 summarized 86:5,22 130:19 137:22 60:12 65:9 66:9,17
172:6 198:22 131:15 149:3 151:10 167:7 66:18 67:7,13,14,15
224:16 255:11 summarizes 73:12 167:11 169:9 69:10 71:8,21 72:6
304:1,8,10,16 summary 12:10 52:3 214:20 264:15 72:7 73:2 75:6,6,7
317:17 318:17 222:1 238:6 283:16 301:15 75:13,18,19,21,22
321:4 summer 145:16 303:4 309:9,16 77:6,7,14 78:16
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88:4,11,14 89:1,3,5 254:8 261:19 systemic 189:1 206:3 193:8 270:15
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93:13 94:11,12 267:10 268:3 269:3 238:11 239:11 285:14 295:16
100:8,10,13 102:17 269:5 304:21 270:21 271:7 298:20 309:5
103:5,11 104:2,3,20 309:11 313:7 272:15 273:15 talked 169:1 270:16
104:21 106:11,13 316:19 321:11,14 274:4,16 297:17 307:10 322:19
106:15,16 110:18 328:13 331:1,1 298:6 talking 127:4 128:21
112:4,21 113:4,5,7 survivals 72:1 218:4 systemically 241:13 128:21 130:16
113:8,13,15,18,21 survival-driven 273:18 131:1,12 174:2
114:1,3 115:15 310:8 systems 192:11 175:3 276:20
116:18,20 118:15 survive 100:17 S-E-S-S-I-O-N tantalizing 270:10
118:18,21 119:14 137:22 153:7 177:1 180:10 tantamount 32:17
119:20 122:10,17 246:20 131:3
124:4,8,13,17 survived 150:2 T taper 195:12,15
126:21 129:1,2,7 262:11 T 9:16 11:1,1 12:1,1 205:7,10 229:7
131:1,14 132:15,20 surviving 38:7 196:7 297:17
132:22 133:19,21 survivor 139:19 table 17:21 51:10 tapered 200:19
133:22 134:3,11 147:2 277:2,3 81:2 86:22 153:21 229:11
142:17 143:21 Susan 4:14 276:9 163:4,19 164:18 target 31:19 190:18
144:2 150:10,14 278:15 174:13,16 180:19 targeted 143:12
154:12 156:10 sustained 325:14 183:17 231:15 152:1 197:18
160:16 161:7 164:2 swallow 253:1 236:15 318:12 taste 277:4
164:5,8,12,15,22 swelling 25:9 324:9 team 7:18 8:2 14:19
165:6,8,13 168:8,16 swim 147:6 tablet 186:21 187:1 182:4,7 289:8,10
170:20 171:19 swing 289:19 tablets 186:21 187:4 teammates 289:21
172:1 173:1,3 swings 286:20 228:20 teams 147:6
174:4 175:13,14,14 switch 270:14 tachycardia 86:1 technical 260:6
175:17,17 176:2,3,5 switched 293:7 tacrolimus 192:14 technician 121:21
176:8,10,13,16,20 swollen 137:14 take 22:1 90:7 96:2 Technologies 61:6
177:3,5,11,18,21 symptom 200:6 112:11 116:4 119:2 technology 100:15,15
178:2,3,10,11 206:4 symptomatic 86:13 123:22 154:22 100:16 186:11
207:18 212:1 213:2 symptoms 25:8 54:4 165:13 175:10,11 Ted 186:1 202:13
213:12,13,19 87:19,21 194:12 180:13 198:12 320:8
214:16,18 215:1,7 199:10 215:15 200:15 241:17 teleconferences
215:10 216:21,22 synchronous 92:10 254:4 263:17 265:8 316:21
217:4,9,13,14 219:2 95:5 293:18 306:9 314:3 telephone 229:18
222:13 224:3,9,12 syndromes 221:11 317:19 326:17 tell 98:21 106:4
229:17 230:3,4 synthetic 29:20 327:14,15,16 332:8 125:15 147:1
232:12,22 233:1,2,4 186:14 taken 30:20 122:5 158:18 190:3
233:6,8,9,19,22 Syracuse 293:22 155:6 162:22 180:8 243:10 252:22
234:2,3 235:19 syringe 287:3 284:14 277:18 287:7
236:12,18 237:14 system 21:8 123:3 takes 138:8 153:21 288:18 295:19
237:14 243:1,6,13 187:3 191:2,3 take-home 218:12 telling 19:2 292:22
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tends 92:15 155:22 160:21 60:16 63:2,3,3,6,8 123:20 124:8,16
tenured 52:14 165:16 166:19 63:20 64:22 65:4,6 128:19 129:17
term 30:14 46:10 167:17 169:21 68:1 73:18 74:1,2,3 130:13,20 131:3
48:22 244:8 171:9 173:12 81:5 85:16 86:4,21 132:16 135:2 155:5
terminal 197:13 178:15 179:3,22 87:3,9,15 88:2 156:17,21 157:15
terms 98:22 121:10 180:4,6 182:12 98:20 111:12 119:6 159:5 160:2,5,11
127:5,13,13 161:1 184:6,17 189:20 119:10 148:8 167:7 161:13 162:3 163:2
217:4 224:3 245:17 190:1 225:14,15 168:8,18 177:10 163:12,20 164:2,4
253:14 254:8 259:7 231:9 238:4,7 187:4 192:9 193:13 164:12 165:1,4
259:16 261:18,20 239:19,20 240:18 193:22 195:1,21 166:3,5,8,11,15
262:13 263:14,15 241:4 242:2 244:11 197:2 204:2,3 167:3,12 168:6,10
264:17 270:13 258:6 260:1 261:4 208:16 210:3 216:6 169:2,4 171:17
317:7 319:13 324:3 269:11 274:20 216:16 225:8 173:12,22 175:2,8
324:12 276:3,8 278:14,15 228:18 229:17 176:6 177:17
term’s 104:11 284:8 291:1,2 230:13 233:5 179:21 196:15
terrifying 148:17 292:12 294:2,3,7,8 235:20 248:21 203:10,21 204:20
test 19:20 47:4,16,19 294:11 298:20,21 267:7,8 272:5 211:10,16 220:13
78:22 79:6,8 298:22 301:20 274:18 298:18 223:7,16,16,22
104:11,15,21 303:2,5 305:8 327:2 224:2,16 241:7
125:22 128:14,15 306:17 312:9,10 thing 100:16 126:6 242:13,15,17,21
128:15 177:20 313:20 318:5 324:5 150:21 152:13 243:10,20 244:2
207:7 209:16 331:14 333:4 178:13 194:1 245:22 246:7,11,20
210:13 231:20 thankful 331:7 242:21 244:3 247:8 247:8,11 251:6,17
238:18 242:8 Thankfully 151:19 270:15 306:3,8 252:1 253:2,12
289:16 316:12 Thanks 160:5 261:9 327:17 329:19 254:14 256:7,19
tested 28:22 65:7 320:9 things 121:12 128:20 257:5,21 258:15,20
269:8 that’s 28:14 103:3 129:1 134:15 153:5 259:14,17 260:6
testimony 152:5 104:22 128:7 159:4 172:9 198:16 263:13,20,21 264:2
testing 48:3 106:7 130:19 132:13 210:17 214:21 264:9,20 266:6,9
234:6 239:9 250:15 160:2 162:7 163:2 230:19 247:10 267:2 268:8 269:1
tests 83:7 127:18 163:3 169:20 258:15 259:15 269:20 270:1,9
220:5,7 298:4 172:11 175:9 261:20 266:9 277:6 271:3,10,18,21
Texas 4:16 9:5 194:15 204:11,13 283:17 291:11 272:4 277:1 279:4
145:19 181:22 247:11 252:11 310:7 323:18 279:6 280:6 282:6
textbook 312:21 253:17,19 255:19 324:17 284:6,9,10 285:10
th 198:3 256:5,15,16 259:19 think 90:11,13,15 290:18 293:8
thank 15:10,16 18:10 265:3 266:7 268:18 91:1,4 94:19 96:14 298:18 305:15,17
18:11 19:10 23:14 283:9 284:5,11 97:22 98:6 99:22 305:22 306:2,5,8,10
29:13,16 32:9 52:7 291:17 296:12 100:11,22 101:7,12 306:14,20,21 307:5

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310:17,20,22 311:5 277:6 279:17 245:2 249:17,20 143:10,15 144:1,9
311:8 312:20 291:18 293:18 251:13 258:10 144:22 145:8,11
314:12 315:10 297:7 306:1 309:9 260:9 265:11 266:2 146:21 151:22
316:7,9,21 317:6,9 309:17 316:20 267:7 268:15 152:13 153:12
317:18 319:19,20 323:20 274:18 277:16 159:15 164:5
320:2,5 321:10 three-drug 35:11 279:18,19 280:15 168:14 172:9
322:5,11 323:12,17 61:1 99:3 112:12 281:8,10 282:2 185:16 186:18
326:7,8 327:4,17,19 115:17 286:14 291:1 293:1 189:9 230:6 276:9
327:20,22 329:8,17 thrilled 289:10 294:1 295:5,6 277:1 278:2 289:6
330:10 331:5 throat 285:19 286:14 296:15,17 299:19 289:6 329:6 331:8
332:11,15,20 throw 175:21 292:16 301:11,12,13,18 today’s 17:20 35:11
thinking 162:22 324:19 302:6 306:16 311:7 183:16 185:17
third 30:1 75:16 76:8 thrown 284:21 312:16 315:1,7,21 188:12 189:18
81:15 118:15 thymic 256:10,18 316:22 323:2,9 191:15
Thirdly 110:14 thymolpoiesis 256:12 325:11 328:3 told 139:15 204:18
thirteen 24:22 70:4 tibia 25:7 38:1 147:7 331:18 243:15 278:21
thirties 256:13 tick 172:4,15 173:8 timed 205:14 279:2
thirty 37:20 tide 279:22 timeline 192:8 Tolerability 10:20
Thirty-one 49:16 till 286:18 times 187:4 273:16 52:8
Thirty-three 281:7 Tim 185:18 189:18 273:16 278:19 tolerable 22:8 130:14
thirty-two 74:12 240:14 263:17 285:5 288:6 tolerance 256:19
Thomas 312:21 time 20:9,15,19 time-to 226:14 tolerate 281:22 296:9
thoracic 148:15 24:20 26:19 32:17 time-to-event 132:20 tolerated 43:16 54:12
thoracotomy 151:11 32:19 36:16 37:17 133:2,6,10 202:7,12 54:13 198:21
thoroughly 315:2 49:11 53:14 55:3 207:5 320:11,15 295:19 298:4
thought 85:20 137:3 55:12 57:6 72:6,7 time-to-failure 265:9 312:12
159:4 198:5 201:16 72:10,14,16,19 73:5 time-to-treatment tomorrow 147:12
204:5 214:19 319:9 88:20 90:7 92:4,5 210:16 246:3 332:21
326:10,22 99:3 100:5 108:11 262:19 263:8 320:3 tonight 332:19
thousand 276:20 108:13 111:5 timing 45:13,15 49:8 tool 278:6
327:12 113:18 117:5 49:10 82:1,8 85:14 tools 329:15
thousands 307:7 119:21 127:4 110:16 113:16 top 66:20 79:11 94:9
threatened 332:13 128:21 130:12 117:9 167:15 174:2 287:12
threatening 87:22 133:8 138:8 139:7 168:12 232:14 topic 141:8 332:9
three 19:4 40:22 140:1 141:21 tired 137:2 295:8 topical 186:17 197:9
44:17 69:4 71:22 147:19 150:16 tissue 25:11 30:17,21 197:14 202:1
72:3 76:2 77:22 155:8,21 159:5 31:9 151:17 287:16 206:19 207:3 220:3
81:2 91:4 92:21 167:9 173:8 193:21 325:19 228:14 235:5 238:8
98:15,16 111:2,11 195:3,18 196:7 tissues 31:20 190:17 253:7 271:4,22
111:14 115:13 197:10 200:22 title 61:14 272:4 273:9 274:18
116:17,19 117:3,15 208:14 209:1,6,8 today 13:8 21:20 327:2
117:18 131:8 134:3 212:14,18 213:1,13 22:5 23:18 24:11 topically 197:4
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total 36:5 64:19 41:11 104:9 115:12 216:15,19 217:8
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218:10 250:10 275:4 330:18 187:2 245:19 221:17 222:5,7,10
251:15 transparent 135:15 306:12 312:2 222:11,21 223:19
totality 266:6 313:11 275:2 treated 33:13 44:4 224:20 225:12
313:11 transplant 181:20 60:14 109:3 118:17 226:15,16 230:15
totally 107:7 269:6 189:2 191:12 192:8 140:2 168:3 187:17 231:14,18 232:18
touch 261:8 272:16 192:20 193:10 195:10 197:7 232:20 233:18,21
328:7 199:10 201:1 229:10 251:1,20 235:8,9,10 236:20
touched 272:10 203:22 204:10 317:4 237:20 238:17,20
tough 248:5 205:13,20 209:3,7 treating 32:14 53:10 239:9 241:1 242:9
toughing 250:8 212:1,14,15,18 69:11 74:4 87:13 243:1 244:14
toxic 53:6 87:5 214:1,5 215:15 116:9 186:7 198:3 248:10 249:15,16
toxicities 42:8,10,12 217:19 225:4 278:7 309:11 250:5,20 251:4,10
42:15 43:10,11 230:17 232:14 treatment 11:19 13:9 258:7,13 259:1,4,12
49:18 85:12 86:2,3 235:16 245:2 247:2 20:22 24:9,14 262:2 263:1,3,5
86:20 247:4 252:17 28:11,15 31:16 266:12,17 269:22
toxicity 44:10 54:10 253:18 254:21 33:20,22 35:15 271:4 292:5,13
85:12,15 100:21 255:5 256:12 270:5 39:15 41:13 43:6 293:9,10 295:2
257:18,20 285:16 270:13 276:7,11,18 43:18,21 53:20 296:2 306:10
329:1,4 276:21 278:22 54:15 55:15 56:16 307:19 308:1,16,18
to-treatment 229:15 279:8 283:4,7 60:2 61:12,18 63:1 311:4 313:5,8,16
TPN 203:6 247:20 284:18 288:1,7 65:11,13 75:9 321:1 323:7 325:12
248:2,4,6,9,15,21 289:7 291:8,9,11 77:15 79:6,16 326:12 327:2 330:2
248:21 249:2,6,11 293:21 294:14 80:15,20 83:7,11 treatments 22:8
249:12,13,14 307:7 312:7 322:3 85:18 86:17 87:6 24:17 34:11 137:6
279:17 285:1 289:2 324:20 325:18 90:16,20 96:20 167:10 186:8
292:19,19 transplantation 6:5 98:13 99:9 106:12 270:19 290:15
track 283:4 184:22 186:4 106:14 116:14 treatment-emergent
tracked 249:18 190:15 254:17 127:2 139:13,16,17 316:6
tract 11:21 189:6 295:3 144:15 150:8,19 treatment-related
190:19 197:19 transplanted 255:11 151:5 156:20 218:14,14
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22 83:19 208:12 277:17 297:22 400 60:9 273:16 323:8,13
210:8 227:10 288:5 313:2,6 323:11 41 10:19 310:13 500 27:2 55:20
22-092 11:3 30-day 205:2,11 42 208:12 227:9 505 174:17
228 45:6,21 82:7 210:20 322:16 286:3 506 292:12
229 12:7 30-year 312:13 43 49:21 208:9 51 84:2 238:19 239:9
23 220:10 278:19 300 289:7 431 296:17 519 72:21
235 12:9 300-day 289:6 44 219:11 53 48:22 282:17
24 25:21 33:21 64:18 309 12:15 45 218:1 223:4 530 83:21 84:5 129:9
95:18 285:1 31 84:1,2,3 174:19,21 46 117:21 119:5 54 210:11 215:22
175:1 209:13 165:10 210:11 217:22 286:2

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600 25:2 55:17 57:12 116:21 120:6 97 99:21
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