You are on page 1of 13

Zoster is a common, predominantly dermal, and neurologic disorder caused by the varicella-zoster virus (VZV), a virus morphologically

and antigenically identical to the virus causing varicella (chickenpox). Difference in clinical manifestations between varicella and zoster apparently depends on the immune status of individual patients; those with no prior immunologic exposure to varicella virus, most commonly children, develop the clinical syndrome of varicella, while those with circulating varicella antibodies develop a localized recrudescence, zoster. Zoster probably results most often from a failure of the immune system to contain latent varicella-zoster virus replication. Whether other factors such as radiation, physical trauma, certain medications, other infections, or stress also can trigger zoster has not been determined with certainty. Nor is it entirely clear why circulating varicella antibodies and cell-mediated immune mechanisms do not prevent recurrent overt disease, as is common with most other viral illnesses. An inverse correlation appears to exist between the capacity of a host to mount a cellular immune response and the incidence of zoster. However, many patients with zoster apparently have normal immune systems. In these patients, zoster is postulated to occur when varicella-zoster virus antibody titers and cellular immunity drop to levels at which they no longer are completely effective in preventing viral invasion. Evidence for this hypothesis includes the observation that pediatricians, who presumably are reexposed to the varicella virus routinely and thus maintain high levels of immunity to varicella-zoster virus, seldom develop zoster. Zoster most commonly manifests in 1 or more posterior spinal ganglia or cranial sensory ganglia, presumably because viral particles have been preserved within these ganglia in a dormant state since the original episode of varicella. This results in pain and characteristic cutaneous findings (see History) along the corresponding sensory dermatomes of the involved ganglia. Less often, involvement of anterior and posterior horn cells, leptomeninges, and peripheral nerves is observed, with consequent muscle weakness or palsy, pleocytosis of spinal fluid, and/or sensory loss. Rarely, myelitis, meningitis, encephalitis, or visceral involvement may occur.

Shingles facts

Shingles is caused by the same virus that causes chickenpox and can be spread to people who have not had chickenpox. Shingles, also known as herpes zoster, is not related to thesexually transmitted herpes virus disease called herpes genitalis, or the oral herpes virus, herpes simplex. Shingles may cause pain that can continue after the rashdisappears. Steroids and antiviral drugs can help prevent long-term pain after shingles if they are started within the first two days of the appearance of the rash. The Zostavax vaccine is available for people over 60 years of age to reduce the incidence and severity of shingles.

 

What is shingles? What causes shingles?
Shingles is a skin rash caused by a nerve and skin inflammation from the same virus that previously caused chickenpox. This virus is called thevaricella zoster virus (VZV) and belongs to the herpes family of viruses. After an individual has chickenpox, this virus lives dormant in the nervous system and is never fully cleared from the body. Under certain circumstances, such as emotional stress, immune deficiency (from AIDS orchemotherapy), or with cancer, the virus reactivates and causes

How long is shingles contagious? Shingles is contagious and can be spread from an affected person to babies.shingles. The duration of the outbreak may take three to four weeks from start to finish. children. The entire path of the affected nerve may be involved. Shingles rash starts as small blisters on a red base. with new blisters continuing to form for three to five days. Anyone who has ever had chickenpox is at risk for the development of shingles. the pain of shingles may be apparent. more than one nerve will be involved. Eventually. . a cause for the reactivation of the virus is never found. This can be a very confusing cause of local pain. Generally. Once infected. although it occurs most commonly in people over the age of 60. however. In most cases of shingles. and the area starts to ooze. In a rare case. or adults who have not had chickenpox. the pain will be present but the blisters may never appear. people cannot catch shingles (or contract the virus) from someone else. Shingles is medically termed herpes zoster. But instead of developing shingles. the patient may notice several days to a week of burning pain and sensitive skin.S. the blisters pop.000. or there may be areas in the distribution of the nerve with blisters and areas without blisters. Before a rash is visible.000 cases of shingles occur each year in the U. What are shingles symptoms and signs? How long does shingles last? Even when there is no rash. only one nerve level is involved. On occasion. When the characteristic rash is not yet apparent. however. It has been estimated that up to 1. The affected areas will then crust over and heal. Once they have had chickenpox. these people develop chickenpox. people have the potential to develop shingles later in life. The herpes virus that causes shingles and chickenpox is not the same as the herpes viruses that causes genital herpes (which can be sexually transmitted) or herpes mouth sores. The blisters follow the path of individual nerves that come out of the spinal cord in a specific "ray-like" distribution (called a dermatomal pattern) and appear in a band-like pattern on an area of skin. it may be difficult to determine the cause of the often severe pain.

as long as there are new blisters forming and old blisters healing. may also provide . Cool compresses and anti-itching lotions. particularly in people with impaired immune function. such as acyclovir (Zovirax). such ascalamine lotion. Both nonsteroidal antiinflammatory medications and narcotic pain-control medications may be used for pain management in shingles. is usually sufficient to establish the diagnosis. samples from the affected area may be tested in a laboratory. Drugs that fight viruses (antivirals). The affected area should be kept clean. can reduce the severity and duration of the rash if started early (within 72 hours of the appearance of the rash). either by culturing the tissue for growth of the virus or by identifying the genetic material of the virus. No diagnostic tests are usually required. In these cases. or famciclovir(Famvir). How is shingles diagnosed? The clinical appearance of shingles. What is the treatment for shingles? Should I visit my health care professional? There are several effective treatments for shingles. shingles may sometimes not display the characteristic clinical pattern. pain medications may be needed for symptom control. Once all of the blisters are crusted over. with characteristic painful blisters localized to the region of a specific nerve. Similar to chickenpox. and the area can be cleansed with soap and water. the virus can no longer be spread and the contagious period is over. the time prior to healing or crusting of the blisters is the contagious stage of shingles. In addition to antiviral medications.valacyclovir (Valtrex).What does shingles look like? Shingles is contagious to people who have not previously had chickenpox. However. Bathing is permitted.

and X) are involved. it is possible. your eyes should be evaluated by a health care professional. specifically the forehead and nose. contact your health care professional. a bacterial infection of the skin.relief. the blisters can become infected with bacteria. warm. and tender. shingles heals well and problems are few. IX. A rare complication of shingles is known asRamsay Hunt syndrome. If this occurs. leading to loss of vision. Antibiotics can be used to treat these complications. although not likely. What are the complications of shingles? Generally. In this situation. If you have shingles on your forehead or nose. available at your pharmacy) can be used to help dry up the blisters and oozing. . If you notice any of these symptoms. on occasion. The typical rash is often observed around the ear and ear canal. You might notice red streaks forming around the wound. An aluminum acetate solution (Burow's orDomeboro solution. the area will become reddened. the cranial nerves (cranial nerves V. that shingles can affect the eye (known as herpes zoster ophthalmicus). firm. In this case. A more worrisome complication occurs when shingles affects the face. Symptoms may include peripheral facial nerve weakness anddeafness. However. causingcellulitis.

Picture: How the varicella zoster virus causes shingles and postherpetic neuralgia What is postherpetic neuralgia? The most common complication of shingles is postherpetic neuralgia. Postherpetic neuralgia occurs primarily in people over the age of 50 and affects 10%-15% of people with shingles. a derivative of hot chili peppers. carbamazepine [Tegretol]. The pain of postherpetic neuralgia can be reduced by a number of medications. even after the rash is gone. to reduce the pain. Tricyclic antidepressant medications (amitriptyline [Elavil] and others).Lidocaine pain patches (Lidoderm) applied directly to the skin can also be helpful in relieving nerve pains by . This occurs when the nerve pain associated with shingles persists beyond one month. Capsaicin cream(Zostrix). as well as antiseizure medications (gabapentin[Neurontin].pregabalin [Lyrica]). previously used for the management of restless legs syndrome. the FDA approved the use of gabapentin enacarbil (Horizant). have been used to relieve the pain associated with postherpetic neuralgia. The pain can be severe and debilitating. There is evidence that treating shingles with antiviral agents can reduce the duration and occurrence of postherpetic neuralgia. can be used topically on the area after all the blisters have healed. In 2012. It is a result of irritation of the nerves of sensation by the virus. for the treatment of postherpetic neuralgia.

cancer treatment.numbing the nerves with local lidocaine anesthetic. see above) by at least two-thirds. shingles inpregnancy is very rare. It is a onetime injection (shot) that does not need to be repeated. This rash should be kept covered and will disappear on its own. People with weakened immune systems due to immune-suppressing medications. Centers for Disease Control and Prevention recommends the vaccine for people 60 years of age and over who have had chickenpox. Is shingles dangerous in pregnant women? Pregnant women are susceptible to shingles. . Tests over an initial four-year period showed that the vaccine significantly reduced the incidence of shingles in these older adults. The shingles vaccine contains a booster dose of the chickenpox vaccine usually given to children. the U. Even if you have had shingles. and headache. acetaminophen(Tylenol) is considered safe even in the late stages of pregnancy. or itching at the shot site. It has not been demonstrated that a person can develop chickenpox from getting the shingles vaccine. Studies are ongoing to evaluate the effectiveness of the vaccine over a longer term. Food and Drug Administration (FDA) approved the first vaccine for adult shingles. The shingles vaccine has not been shown to cause any serious side effects or health consequences. Can shingles be prevented with a vaccine? In May 2006. or organ transplants should not receive the shingles vaccine because it contains live.S. The single-dose vaccine was shown to be more than 60% effective in reducing shingles symptoms. but fortunately. These options should be discussed with your health care professional. women should not take nonsteroidal antiinflammatory medications such as ibuprofen (Advil) ornaproxen (Aleve). In the later stages of pregnancy. is approved for use in adults ages 50 and over who have had chickenpox. The vaccine known as Zostavax. This is also expected to reduce the incidence of shingles in adults in the future as these vaccinated children age. although some people who receive the vaccine may develop a mild chickenpox-like rash near the injection site. you can still have the vaccine to help prevent future outbreaks. The U. soreness. There are certain contraindications to receiving the shingles vaccine.HIV disease. as are most pain-relieving drugs. the incidence of chickenpox has been reduced. However. Minor side effects include redness. weakened viral particles.S. Since the chickenpox vaccine is now recommended for children. swelling.Pregnant women should not receive the shingles vaccine. It is safe for those who have received the shingles vaccine to be around babies or those with weakened immune systems. There is not enough information available from researchers to decide at this point whether Zostavax may be beneficial in people younger than 60 years of age. The antiviral medications described above are considered safe to use in pregnant women. and it reduced the incidence ofpostherpetic neuralgia (PHN.

In immunocompromised hosts. Both are closely related but differ in epidemiology. Symptomatic infections can be characterized by significant morbidity and recurrence. sunlight. infections can cause lifethreatening complications. menstruation). HSV is distributed worldwide. Humans are the only natural reservoirs. fever. Endemicity is easily maintained in most human communities owing to latent infection. resulting in overt or covert recurrent infection and shedding of HSV. In immunocompetent persons who are at an equal risk of acquiring HSV-1 and HSV-2 both orally and genitally.The shingles vaccine should not be administered to pregnant women. If you do not know if you have had chickenpox. HSV-2 reactivates 8-10 times more commonly in the genital region than in the orolabial regions. in genital HSV infection. Herpes simplex viruses are ubiquitous. however. cervix. and asymptomatic virus shedding.[2] Dissemination of herpes simplex infection can occur in people with impaired T-cell immunity. always in the area supplied by the ganglia in which latency was established. . It is a double-stranded DNA virus characterized by the following unique biological properties: [1]   Neurovirulence (the capacity to invade and replicate in the nervous system) Latency (the establishment and maintenance of latent infection in nerve cell ganglia proximal to the site of infection): In orofacial HSV infections. HSV-1 reactivates more frequently in the oral rather than the genital region.[3] HSV is transmitted by close personal contact. Two types exist: herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). and infection occurs via inoculation of virus into susceptible mucosal surfaces (eg. a blood test can determine whether you have antibodies (immune protection) against the virus. The risk of birth defects is believed to be lower with shingles than with primary chickenpox infection. can be induced by various stimuli (eg. host-adapted pathogens that cause a wide variety of disease states. such as in organ transplant recipients and in individuals with AIDS. making it a major public health concern. periodic reactivation. Up to 80% of herpes simplex infections are asymptomatic. lesion location is not necessarily indicative of viral type. Similarly. while HSV-2 is traditionally associated with genital disease. It is recommended that a woman wait three months before trying to become pregnant after she has received the shingles vaccine. while. trauma. depending upon when in the pregnancy the infection occurs. and no vectors are involved in transmission. the sacral nerve root ganglia (S2-S5) are involved. aerosol and fomitic spread are rare. Those who received the chickenpox vaccine as well as those who have previously had chickenpox will have antibodies in their blood that are directed against the VZV virus. The prevalence of HSV infection worldwide has increased over the last several decades. HSV (both types 1 and 2) belongs to the family Herpesviridae and to the subfamily Alphaherpesvirinae. emotional stress. the trigeminal ganglia are most commonly involved.  Reactivation: The reactivation and replication of latent HSV. HSV-1 is traditionally associated with orofacial disease. Reactivation is more common and severe in immunocompromised individuals. hence. Having chickenpox during pregnancy has the potential to cause birth defects. Prompt recognition of herpes simplex infection and early initiation of therapy are of utmost importance in the management of the disease. conjunctiva) or through small cracks in the skin. The virus is readily inactivated at room temperature and by drying. oropharynx.

Poxvirus ini berasal dari family poxviridae. lebih besar daripada mRNA ditemukan pada ribosom. atau ditentukan oleh gen virus atau selular. yang paling penting yang merupakan virus terkait DNAdependent RNA polimerase. virus ini menyebar dari orang ke orang dengan menyentuh kulit yang terkena. Regulasi dilakukan oleh protein hadir dalam virion. yang dinyatakan di hadapan inhibitor sintesis protein. Intermediet replikatif. dengan virus DNA yang paling hanya sebagian kecil dari genom ditranskripsi menjadi utusan awal. benjolan dapat menyebar ke bagian lain dari tubuh mereka dengan menyentuh atau menggaruk benjolan dan kemudian menyentuh bagian lain dari tubuh. Proses Replikasi Virus DNA yaitu pada Poxvirus transkripsi terjadi pada inti dan terjemahan dalam sitoplasma. dan dalam beberapa kasus. Vaksinasi empat sampai tujuh hari setelah terinfeksi dapat menawarkan beberapa perlindungan dari penyakit atau dapat memodifikasi keparahan penyakit. Para utusan virus. merupakan penyakit penyebab cacar. hadir dalam sitoplasma. dan bantuan ventilator. Virus ini terbuat dari membran Golgi dimodifikasi mengandung virus-spesifik polipeptida. Selain vaksinasi. berinteraksi dengan urutan peraturan di ujung 5 ‘gen. dan tertunda gen awal. yang concatemers khusus berisi pasang genom tersambung baik kepala atau ekor. Umumnya. . seperti sel-sel hewan. atau mainan. Biasanya terjadi infeksi pada kulit. Biasanya terjadi infeksi pada kulit. Ciri mencolok dari DNA poxvirus adalah bahwa kedua untai komplementer bergabung. merupakan penyakit penyebab cacar. Siklus hidup poxvirus rumit dengan memiliki bentuk infeksi ganda. sisa genom ditranskripsi menjadi utusan terlambat.Pengertian Poxvirus merupakan virus lengkap yaitu virion dan dari inti asam nukleat yang dikelilingi lapisan protein yang bersifat antigenik yang disebut dengan kapsid dan terdapat selubung luar (envelope) yang terdiri dari protein dan lipid. Kedua virion menyelimuti dan unenveloped yang menular. pakaian. Transkripsi memiliki organisasi temporal. Untuk mereplikasi. termasuk hemaglutinin. Penanggulangan Cacar dapat dilakukan dengan vaksinasi dalam waktu tiga hari setelah terinfeksi akan mencegah atau secara signifikan mengurangi keparahan gejala cacar di sebagian besar orang. bagaimanapun. Setelah seseorang memiliki virus. yang dihasilkan oleh RNA polimerase II. virus ini menyebar dari orang ke orang dengan menyentuh kulit yang terkena. Infeksi dengan baik variola besar atau variola minor menciptakan kekebalan terhadap yang lain. yang monocistronic. Virus kompleks memiliki gen awal langsung. seperti perawatan luka dan pengendalian infeksi. Virus ini juga dapat menyebar dengan menyentuh permukaan dengan virus di atasnya. poxvirus menghasilkan berbagai protein khusus yang tidak diproduksi oleh virus DNA lainnya. transkrip primer. Setelah sintesis DNA. Poxvirus ini berasal dari family poxviridae. dengan mekanisme yang berbeda dan masuk ke sel. yang membutuhkan sintesis protein untuk berekspresi. terapi cairan. pengobatan cacar. sebanyak 30% dari RNA ditranskripsi tetap diterjemahkan dalam nukleus. seperti handuk. —Pengertian Poxvirus merupakan virus lengkap yaitu virion dan dari inti asam nukleat yang dikelilingi lapisan protein yang bersifat antigenik yang disebut dengan kapsid dan terdapat selubung luar (envelope) yang terdiri dari protein dan lipid. Sintesis protein awal adalah langkah awal penting dalam replikasi DNA virus. Poxvirus adalah unik di antara virus DNA dalam bahwa mereka bereplikasi dalam sitoplasma sel bukan di inti.

Gejala yang terjadi bagi yang terinfeksi adalah demam. Penyakit cacar dalam bahasa medis disebut variola. tangan. Penyakit ini nama ilmiahnya adalah impetigo bulosa. Cacar air. Perlu diketahui. pengobatan cacar.Urutan ini dapat menanggapi di trans untuk produk yang dihasilkan oleh gen lain dan bertindak dalam cis pada gen yang terkait. Hal ini disebabkan daya tahan tubuh yang baik yang dapat menekan virus ini berkembang. Bagi yang bisa sembuh pun. virus tersebut tidaklah musnah seluruhnya dari tubuh penderita. tepatnya di ganglion saraf tepi penderitanya. Penyakit yang disebabkan oleh virus poks (pox virus) ini sudah ada sejak berabad-abad yang lalu dan sangat mudah menular. Vaksinasi empat sampai tujuh hari setelah terinfeksi dapat menawarkan beberapa perlindungan dari penyakit atau dapat memodifikasi keparahan penyakit. sedangkan dalam bahasa Inggris disebut small pox. Penyakit ini disebabkan oleh virus yang bernama virus varisela-zoster. Penanggulangan Cacar dapat dilakukan dengan vaksinasi dalam waktu tiga hari setelah terinfeksi akan mencegah atau secara signifikan mengurangi keparahan gejala cacar di sebagian besar orang. dada. bila seseorang terkena infeksi virus varisela-zoster untuk pertama kali. Virus yang berdiam dalam tubuh penderita ini dapat sewaktu-waktu muncul kembali dan menyebabkan penyakit yang dinamai Herpes Zoster. Gejala berupa gelembung yang muncul kecil-kecil dan tidak serentak. Cacar air. cacar ular dan cacar monyet. Secara umum. Setelah sembuh. Penyakit ini kerap berakibat fatal. terutama bila mengenai bayi atau lanjut usia. dalam bahasa medisnya disebut ‘varisela’. Selain vaksinasi. Kelas yang berbeda mungkin gen ditranskripsi dari untai DNA yang berbeda dan oleh karena itu dalam arah yang berlawanan misalnya polyomaviruses. Istilah cacar monyet memang relatif tidak sepopuler istilah cacar lainnya yang telah disebutkan di atas. Penyakit ini merupakan bentuk reaktivasi penyakit cacar air (varisela) yang pernah diderita seseorang sebelumnya. walaupun namanya mirip dengan cacar. cacar monyet ini disebabkan oleh bakteri Staphylococcus aureus. Secara klinis. kaki. dan dalam bahasa Inggris dinamai chicken pox. dan punggung. Modus replikasi adalah semikonservatif tetapi sifat intermediet replikatif tergantung pada cara replikasi. atau ada pula yang menamakan impetigo vesikulo-bulosa. seperti perawatan luka dan pengendalian infeksi. Berbeda dengan jenis cacar lainnya yang disebabkan karena infeksi virus. Gejala yang didapatkan adalah adanya gelembung yang munculnya terutama di ketiak. Gelembung yang muncul ini cepat pecah dan jumlahnya tidak begitu banyak. tak jarang penyakit ini tiba-tiba muncul menyerang. maka akan timbul penyakit cacar air. namun kerap kali disertai pula oleh miliaria (biang keringat). penyakit cacar air ini jauh lebih ringan dan tidak berbahaya seperti penyakit cacar. dan akhirnya seluruh tubuh. merupakan penyakit yang berbeda. Sebaliknya. penderita tidak mengalami demam ataupun gejala umum seperti pada cacar air ataupun herpes zoster. Transkrip dapat menjalani proses pasca-transkripsi sehingga urutan intervensi yang tidak penting akan dihapus. Walaupun di dalam tubuhnya terdapat virus ini. dan muncul gelembung-gelembung berisi nanah secara serentak di kulit daerah wajah. . pada orang yang daya tahannya sedang menurun. namun kebanyakan orang memang tidak mengalami penyakit Herpes Zoster. Penyakit cacar yang disebabkan oleh poxvirus ini ada beberapa macam diantaranya yaitu cacar air. dan bantuan ventilator. akan memberikan bekas di kulit berupa bopeng-bopeng. melainkan berdiam di dalam tubuh penderita. terapi cairan. yang dimulai dari bagian tubuh penderita lalu menjalah ke anggota tubuh lainnya. Cacar ular adalah nama awam untuk penyakit Herpes Zoster.

with frequent failures and recurrences. and 35. resolve spontaneously within a few years even without treatment. Certain HPV types tend to infect skin at particular anatomic sites. 18. and 47 have oncogenic potential in patients with epidermodysplasia verruciformis. however. and deep palmoplantar warts (myrmecia). and plantar cysts. Many warts. Less common manifestations of HPV infection include focal epithelial hyperplasia (Heck disease). . The HPV virus infects the epithelium. flat warts. Warts can affect any area on the skin and mucous membranes. 8. 16.[1] epidermodysplasia verruciformis. A small number of high-risk HPV subtypes are associated with the development of malignancies. HPV types 5. and predisposing factors include disruption to the normal epithelial barrier. however. Treatment is difficult. Currently. genital warts.Warts are benign proliferations of skin and mucosa caused by the human papillomavirus (HPV). Viral replication occurs in differentiated epithelial cells in the upper level of the epidermis. The primary clinical manifestations of HPV infection include common warts. warts of any HPV type may occur at any site. 20. more than 100 types of HPV have been identified. Malignant transformation most commonly is seen in patients with genital warts and in immunocompromised patients. including types 6. viral particles can be found in the basal layer. however. 11. 31. Warts are transmitted by direct or indirect contact. and systemic dissemination of the virus does not occur.

such as a towel. Once someone has the virus. Although not limited to children. The virus causes small white. The bumps may appear anywhere on the body. it is most common in children 1 to 10 years of age. HIV-infected persons or persons being treated for cancer) are at higher risk for getting molluscum. the growths range from about the size of a pinhead to as large as a pencil eraser (2 to 5 millimeters in diameter). Researchers who have investigated this idea think it is more likely the virus is spread by sharing towels and other items around a pool or sauna than through water. of Dermatology. Molluscum is common enough that you should not be surprised if you see someone with it or if someone in your family becomes infected. Molluscum usually disappears within 6 to 12 months without treatment and without leaving scars. MD. the bumps can spread to other parts of their body by touching or scratching a bump and then touching another part of the body. and their growths may look different. or toys. Typical bumps are approximately 3-5 mm in diameter. In most people.. pink. Some growths may remain for up to 4 years. There is evidence that molluscum infections have been on the rise in the United States since 1966. MPH. saunas. clothing. Although the virus might be spread by sharing swimming pools. Walter Reed Army Medical Center View large image >Molluscum contagiosum is caused by a virus and usually causes a mild skin disease. alone or in groups. Image courtesy Scott Norton. Dept. and be more difficult to treat. this has not been proven. The virus affects only the outer (epithelial) layer of skin and does not circulate throughout the body in healthy people. although they may be itchy. or other wet and warm environments. Top How do people become infected with the molluscum virus? The virus that causes molluscum is spread from person to person by touching the affected skin.What is molluscum contagiosum? A single molluscum bump on the neck of an adult man.e. humid climates and where living conditions are crowded. but these infections are not routinely monitored because they are seldom serious and routinely disappear without treatment. be larger. They are usually painless. or flesh-colored raised bumps or growths with a dimple or pit in the center. Top . The virus may also be spread by touching a surface with the virus on it. red. Top Who gets molluscum contagiosum? Molluscum infections occur worldwide but are more common in warm. The bumps are usually smooth and firm. Molluscum can be spread from one person to another by sexual contact. swollen and/or sore. People with weakened immune systems (i. baths.

abdomen. For handwashing tips. bump(s). alone or in groups.How would I know if I had molluscum contagiosum? Close-up view of typical molluscum bumps. arms. legs. If you have molluscum. sore and red and/or swollen. Continue for 10–15 seconds. and genital area. The growths are usually painless but may become itchy. Image courtesy Dave Bray. Good hand hygiene is the best way to avoid getting many infections including molluscum. They can be as small as the head of a pin and as large as a pencil eraser (2 to 5 millimeters in diameter). pink.   Do not touch. contact a health care provider. Rinse well and dry your hands. . WRAMC View large image > Only a health care provider can diagnose molluscum infection. see the Clean Hands Saves Lives sitelet at http://www. Soap combined with scrubbing action helps dislodge and remove germs. or scratch any skin with bumps or blisters (yours or someone else’s). you will see small white.gov/cleanhands. Typical bumps are approximately 3-5 mm in diameter. or flesh-colored raised bumps or growths with a pit or dimple in the center. or blister(s) that do not disappear in a few days. By washing your hands frequently you wash away germs picked up from other people or from contaminated surfaces. you should see a health care provider. pick. Only a health care professional can diagnose molluscum. Top How can I avoid becoming infected with molluscum? The best way to avoid getting molluscum is by following good hygiene habits. Next rub your hands vigorously together and scrub all surfaces. He or she will discuss treatment options and how to care for the affected skin. The bumps are rarely found on the palms of the hands or the soles of the feet. Top What should I do if I think I have molluscum contagiosum? If you have any unusual skin irritation. rash. or blisters that do not disappear in a few days. MD. The bumps are usually smooth and firm. They may occur anywhere on the body including the face. bumps. rash. If you have any unusual skin irritation. Top What is the correct way to wash my hands?     First wet your hands and apply soap.cdc. neck.