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EXPIRATION:
z It is a passive process.
z It is due to elastic recoil of the lungs and thoracic wall.
Pleural pressure:
Different types of pressure
1. Intrapleural pressure- pressure within the pleural space. It is also
called intra thoracic pressure.
1. Intrapleural pressure:
At the start of quiet inspiration, it is -2.5 mmHg. At the end of inspiration, It
becomes -6 mmHg.
11. Forced vital capacity: Maximum volume of air that can be breathed
out forcefully and rapidly after a maximum inspiration.
It comprises of: FEV1, FEV2 and FEV3
COMPLIANCE:
Lungs have the tendency to recoil inwards and chest wall has tendency to
expand outwards. The tendency of lungs to recoil back from chest wall is
regulated by 2 forces:
1. Recoil of elastic tissue of lungs.
2. Surface tension within the alveoli.
Law of Laplace: P = 2T/ R.
P is distending pressure, T is surface tension, R is radius.
SURFACTANT:
Increasing surfactant
1. Cortisol
2. Thyroid hormones
APPLIED:
WORK OF BREATHING:
ALVEOLAR VENTILATION:
DEAD SPACE:
Amount of air in the respiratory passage, that does not take part in gaseous
exchange
TWO TYPES:
Any factor that alters alveolar ventilation and pulmonary blood flow alters
the V/P ratio.
Increased by
1. Exercise.