name: Senokot 187 mg Tablet/ granules Category: laxative Formulation: Tablets each tablet contains 187 mg equivalent standardized

d senna concentrate Granules each teaspoonsful contains 337 mg equivalent standardized senna concentrate For reliable of functional constipation through gentle, effective peristaltic stimulation. -have virtually colon-specific action, inducing efficient, yet gentle peristalsis -does not act by irritation of the colonic mucosa -have virtually no effect on motility of the stomach and small intestine Mechanism of action: Senokot preparations contain glycosides (the natural principles of senna) which, upon ingestion, exert no action in the stomach or small intestine. In the colon, according to current theory, enzymatic action converts the inactive glycosides into active aglycones which act specifically in the large bowel through the auerbachs plexus to stimulate peristalsis. Clinically confirmed: Over a decade of wide clinical experiences and a wealth of published clinical and pharmacologic evidence have established Senokot Tablets/granules as a laxative of choice in functional constipation. Senokot preparations help to: -relieve and control chronic constipation -lighten the burden of constipation in the aged -gently relieve constipation of pregnancy and the puerperium -counteract and prevent drug-induced constipation -smoothly relieve post-surgical constipation -mitigate the hazards of constipation in cardiovascular disorders -facilitate dieting without constipation -solve the problem of chronic constipation in chronic illness -help ease the stress and distress of constipation associated with hemorrhoids Virtually Free from side effects: The action of Senoko tablets and granules is virtually limited to the colon. In proper dosage, there is usually no intestinal turmoil, cramping, or gripping that occur with orindary laxatives and harsh purgatives. Reliable, Gentle yet effective: Senokot tablets and granules, by their gentle peristaltic stimulation of the colon, help induce comfortable evacuation of well-formed stools, usually within 8 to 10 hours. This permits administration at bedtime, and easy evacuation the following morning. Its high degree of effectiveness is reflected in satisfactory evacuation achieved in 95.9% of 7,571 patients reported in 31 clinical studies.

High patient acceptance Delicious chocolate-flavored granules; small, easy to swallow tablets. Optimal dosage flexibility to meet the individual needs of your patients. Economical. Rehabilitation potential: Senokot tablets and granules aid in rehabilitation of the constipated patient by facilitating regular elimination. Dosage and Administration: Tablets: (preferably at bedtime) Adult: 2 tablets (maximum dose: 4 tablets two times a day) Children above 60 lbs (27.27kg): one tablet (Maximum dose: 2 tablets two times a day) Granules: Adult: 1 teaspoonful (maximum dose: 2 teaspoonsful twice a day) Children above 60 lbs (27.27kg): one-half teaspoonful (maximum dose: 1 teaspoonful twice a day) Dosage can be adjusted to meet individual requirements. If comfortable bowel movement is not achieved by the second day, increase recommended dose by one tablet (up to maximum dosage) or decrease until the most effective dose is established. In granules, decrease or incrase dose by one-half teaspoonful (up to maximum dosage). Contraindication do not use when abdominal pain, nausea, vomiting, or other symptoms of appendicitis are present, acute abdominal diseae, intestinal hemorrhage, or obstruction , or persistent diarrhea. Store at temperature not exceeding 30 degrees Celsius.

Clexane
Generic Name: Enoxaparin sodium Product Name: Clexane Indication of Clexane Action of Clexane Dose advice of Clexane Schedule of Clexane Common side effects of Clexane Uncommon side effects of Clexane

Indication of Clexane:

Clexane is a medicine that is used to treat blood clots, or stop clots from forming inside the body. Clexane is commonly used to prevent clotting after an operation such as a hip replacement, or in certain heart conditions. ^ top

Action of Clexane:
Clexane works by preventing certain molecules in the blood called clotting factors from working. Clotting factors are needed to from a clot (eg. on a cut or scratch). Sometimes, however, blood clots can form inside the body and travel to areas such as the lungs or brain, where they can from a block. When this happens it is difficult for blood to circulate properly, and the clot may cause severe illness. ^ top

Dose advice of Clexane:

Clexane comes as an injection. Your doctor or nurse will normally give this to you. Clexane is usually injected under the skin of the abdominal (belly) area. In some cases your doctor may show you how to inject yourself with Clexane. You should not attempt to inject yourself with Clexane unless your doctor has shown you how to do this. Clexane is sometimes given to women who are pregnant; your doctor will discuss this with you. Clexane is aPregnancy Category C medicine. Clexane should not be used by breastfeeding women, or by children. ^ top

Schedule of Clexane:
Schedule 4 ^ top

Common side effects of Clexane:

All medicines have side effects. Some side affects can be serious but most are mild. The following is a list of common side effects that occurred in more than 1% but less than 10% of people who took Clexane: Bruising or pain at the place Clexane was injected Bleeding more than normal Talk to your doctor if you experience any side effects. ^ top

Uncommon side effects of Clexane:

The following is a list of side effects that occurred in less than 1% of people who took Clexane. Do not be alarmed by this list. You may not experience any of these side effects. Changes to bone hardness with long term use Hair loss with long term use Allergic reaction Consult your doctor if you experience any of the above symptoms, or any other unusual or abnormal symptoms that concern you. ^ top

Reference:

1.

Australian Medicines Handbook. Clexane .[Monograph online]AMH Pty Ltd 2007[cited December 13, 2007] http://www.amh.net.au

2.

Clexane. MIMs Online. [Monograph online]MIMS Australia Pty Ltd 2007. [Cited December 13, 2007] http://www.mims/com.au ^ top

Diseases treated by Clexane:

Heart Attack (Myocardial Infarction) Pulmonary embolism (PE) Sick Sinus Syndrome (SSS, Bradycardia-tachycardia syndrome)