Drug Study | Epilepsy | Adverse Effect

Name of Drug: Gabapentin

Drug class

■ Nursing considerations

Assessment

Antiepileptic
Therapeutic actions

Mechanism of action not understood; antiepileptic activity may be related to its ability to inhibit polysynaptic responses and block posttetanic potentiation.
Indications

History: Hypersensitivity to gabapentin; lactation, pregnancy ● Physical: Weight; T; skin color, lesions; orientation, affect, reflexes; P; R, adventitious sounds; bowel sounds, normal output

Interventions

Adjunctive therapy in the treatment of partial seizures with and without secondary generalization in adults and children 3–12 yr with epilepsy ● Orphan drug use: Treatment of amyotrophic lateral sclerosis ● Management of postherpetic neuralgia or pain in the area affected by herpes zoster after the disease has been treated ● Unlabeled uses: Hot flashes, neuropathic pain

Give drug with food to prevent GI upset. Be aware that patient may be at increased risk for suicidality; monitor accordingly. ● Arrange for consultation with support groups for people with epilepsy. ≠Warning If overdose occurs, hemodialysis may be an option.
● ●

Teaching points

Contraindications and cautions

Contraindicated with hypersensitivity to gabapentin. ● Use cautiously with pregnancy, lactation.

Adverse effects

CNS: Dizziness, insomnia, nervousness, fatigue, somnolence, ataxia, diplopia, tremor ● Dermatologic: Pruritus, abrasion ● GI: Dyspepsia, vomiting, nausea, constipation, dry mouth, diarrhea ● Respiratory: Rhinitis, pharyngitis ● Other: Weight gain, facial edema, cancer, impotence, suicidal ideation

Take this drug exactly as prescribed; do not discontinue abruptly or change dosage, except on the advice of your health care provider. ● Wear a medical alert ID at all times so that any emergency medical personnel will know that you have epilepsy and are taking antiepileptic medication. ● You may experience these side effects: Dizziness, blurred vision (avoid driving or performing other tasks requiring alertness or visual acuity); GI upset (take drug with food or milk, eat frequent small meals); headache, nervousness, insomnia; fatigue (periodic rest periods may help). ● Report severe headache, sleepwalking, rash, severe vomiting, chills, fever, difficulty breathing, thoughts of suicide.

Name of Drug: Polynerv
Drug class

■ Nursing considerations

Assessment

Antiepileptic
Therapeutic actions

Mechanism of action not understood; antiepileptic activity may be related to its ability to inhibit polysynaptic responses and block posttetanic potentiation.
Indications

History: Hypersensitivity to gabapentin; lactation, pregnancy ● Physical: Weight; T; skin color, lesions; orientation, affect, reflexes; P; R, adventitious sounds; bowel sounds, normal output

Interventions

Adjunctive therapy in the treatment of partial seizures with and without secondary generalization in adults and children 3–12 yr with epilepsy ● Orphan drug use: Treatment of amyotrophic lateral sclerosis ● Management of postherpetic neuralgia or pain in the area affected by herpes zoster after the disease has been treated ● Unlabeled uses: Hot flashes, neuropathic pain

Give drug with food to prevent GI upset. Be aware that patient may be at increased risk for suicidality; monitor accordingly. ● Arrange for consultation with support groups for people with epilepsy. ≠Warning If overdose occurs, hemodialysis may be an option.
● ●

Teaching points

Contraindications and cautions

Contraindicated with hypersensitivity to gabapentin. ● Use cautiously with pregnancy, lactation.

Adverse effects

CNS: Dizziness, insomnia, nervousness, fatigue, somnolence, ataxia, diplopia, tremor ● Dermatologic: Pruritus, abrasion ● GI: Dyspepsia, vomiting, nausea, constipation, dry mouth, diarrhea ● Respiratory: Rhinitis, pharyngitis ● Other: Weight gain, facial edema, cancer, impotence, suicidal ideation

Take this drug exactly as prescribed; do not discontinue abruptly or change dosage, except on the advice of your health care provider. ● Wear a medical alert ID at all times so that any emergency medical personnel will know that you have epilepsy and are taking antiepileptic medication. ● You may experience these side effects: Dizziness, blurred vision (avoid driving or performing other tasks requiring alertness or visual acuity); GI upset (take drug with food or milk, eat frequent small meals); headache, nervousness, insomnia; fatigue (periodic rest periods may help). ● Report severe headache, sleepwalking, rash, severe vomiting, chills, fever, difficulty breathing, thoughts of suicide.

extrasystoles ● Teaching points Take as prescribed. suck sugarless lozenges). or other. avoid excessive dosage. piroxidine (B6). mild. and sedative effects. tremor. energy releasing. such as protein. tremors. All of the above are water soluble. skin. polyneuritis. riboflavin (B2). drowsiness (use caution driving or performing tasks requiring alertness). hallucinations. third trimester of pregnancy. irregular heartbeat. vit B12 1. ● These side effects may occur: Dizziness. palpitations. herpes zoster. uncomplicated urticaria and angioedema. adjunctive therapy in anaphylactic reactions ● Active and prophylactic treatment of motion sickness ● Nighttime sleep aid ● Parkinsonism (including drug-induced parkinsonism and extrapyramidal reactions). hair. reserpine or phenothiazines. lactation. sedation. cyanocobalamin (B12). asthmatic attack. Vitamin B-Complex / with C A11DB . dry mouth (use frequent mouth care.Manufacturer Distributor Contents Indications S V More S V More Vit B1 250 mg. headache. dermatographism. Prophylaxis 1-2 tab daily. diarrhea or constipation (take drug with meals). lumbago. Dosage Administration MIMS Class ATC Classification B-complex consists of eight different vitamins. hematopoietic. restlessness. amelioration of allergic reactions to blood or plasma. stenosing peptic ulcer. rheumatic pains. Indications Adverse effects Relief of symptoms associated with perennial and seasonal allergic rhinitis. excitation. dryness of nasal mucosa (use a humidifier). disturbed coordination. diabetic neuropathy. thickening of bronchial secretions. hyperemesis gravidarum. bladder neck obstruction. confusion. and eyes. maintenance of the liver. loss of coordination. visual disturbances. May be taken w/ meals to reduce GI discomfort. and mitochondrial energy metabolism. epigastric distress. encephalopathies. tachycardia. folic acid (B9). serious sedation could occur. mouth. allergic conjunctivitis. Therapeutic 2-4 tab daily. which include thiamine (B1). sedation. As mentioned above. niacin (B3). cervical & shoulder-arm syndrome. dizziness. has atropine-like. carbohydrate. vitamin b complex can be further broken down in to 3 general categories. pantothenic acid (B5). for milder forms of the disorder in other age-groups. elderly patients who may be sensitive to anticholinergic effects. Used as dietary supplements. ● Report difficulty breathing.000 mcg Neuritis. that is. ● Avoid alcohol. Take with food if GI upset occurs. symptomatic prostatic hypertrophy. nervousness. blurred vision. pyloroduodenal obstruction. iatrogenic complications arising from INH. unusual bleeding or bruising. fat. and play a key role in several bodily functions. pregnancy. and biotin. ● ● . antipruritic. alcoholism. May be taken with or without food. ● Competitively blocks the effects of histamine at H1-receptor sites. ● Use cautiously with narrow-angle glaucoma. fatigue. vasomotor rhinitis. which will be covered thoroughly within the following paragraphs. in the elderly intolerant of more potent drugs. plus so much more. vit B6 250 mg.Vitamin B1 in combination with vitamin B6 and/or vitamin B12 . and in combination with centrally acting anticholinergic antiparkinsonian drugs ● Syrup formulation: Suppression of cough due to colds or allergy ● CNS: Drowsiness. bradycardia. diplopia ● CV: Hypotension. Name of Drug: Diphenhydramine HCl Drug classes Contraindications and cautions Antihistamine Anti–motion-sickness drug Antiparkinsonian Cough suppressant Sedative-hypnotic Therapeutic actions Contraindicated with allergy to antihistamines. cardiac disorders.

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