B.Sc.

Life Sciences
THREE-YEAR FULL-TIME PROGRAMME (Six-Semester Course)

COURSE CONTENTS
(Effective from the Academic Year 2010-2011)

UNIVERSITY OF DELHI DELHI – 110 007

Course Structure
YEAR-1
PART I: Semester – 1 Paper 1 Paper 2 Paper 3 Paper 4 CHPT 101 LSPT 101 MACT 303 ENAT 101*/ CSAT 101* Chemistry-I Biology-I (Introduction to Biology) Mathematics and Statistics Technical writing and Communication in English / Computational skills

PART I: Semester – 2 Paper 5 Paper 6 Paper 7 Paper 8 CHPT 202 LSPT 202 LSPT 203 ENAT 201*/ CSAT 201* Chemistry -II Biology-II Food, Nutrition and Health Technical writing and Communication in English / Computational skills

*The college will have an option to take either of the two papers in a particular semester for a particular course, while students have to appear in both the papers In addition, there shall be one qualifying paper in self-learning mode called Environmental Studies offered in Semester-2

YEAR-2
PART II: Semester – 3 Paper 9 Paper 10 Paper 11 Paper 12 CHPT303 LSPT 304 LSPT 305 LSPT 306 Chemistry -III Biodiversity-I “Microbes” Biodiversity-II “Animals” Introduction to Medical Diagnostics

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PART II: Semester – 4 Paper 13 Paper 14 Paper 15 Paper 16 CHPT 404 LSPT 407 LSPT 408 LSPT 409 Chemistry –IV Molecular Biology Biodiversity-II “Plants” Bioinformatics

YEAR-3
PART III: Semester – 5 Paper 17 Paper 18 Paper 19 Paper 20 CHPT 505 LSPT 510 LSPT 511 LSPT 512 Chemistry –V Biochemistry and Immunology Developmental Biology and Physiology-Plants Genetics & Genomics

PART III: Semester – 6 Paper 21 Paper 22 Paper 23 Paper 24 CHPT 606 LSPT 613 LSPT 614 LSPT 615 Chemistry –VI Applied Biology and Biotechnology Developmental Biology and Physiology-Animals Ecology and Environmental Management

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PREAMBLE

The ongoing B.Sc. Life Sciences course was introduced by the Faculty of Science from the academic year 2005-2006. Broadly, the same course has now been changed to semester-based scheme and shall be effective from the current academic year 2010-2011. However, the opportunity presented by the semester-based scheme has been used for some revision to accommodate the widening horizons of the discipline of biological sciences. Specifically, the subjects on computational skills and bioinformatics have been included so that students can keep pace with the new and expanding information in the field. Two new disciplines: “Food, Nutrition and Health” in Semester II and “Introduction to Medical Diagnostics” in Semester III have been introduced to provide better employment opportunities to Graduate students. In addition, six papers of chemistry covering almost major streams of chemical sciences that should be taught to biology students have also been included. The course content also lists new practical exercises, especially in molecular biology so that the students get a hands-on experience of the latest techniques that are in current usage both in the advanced research laboratories and in Industry.

Paper 1-CHPT 101- Chemistry-1 (Atomic Structure, Bonding, General Organic Chemistry & Aliphatic Hydrocarbons)
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THEORY
Section A: Inorganic Chemistry-1

Marks: 100
(30 Periods)

Unit 1. Atomic Structure: Recapitulation of: Bohr’s theory and its limitations, dual behaviour of matter and radiation, de-Broglie’s relation, Heisenberg Uncertainty principle. Need of a new approach to Atomic structure. What is Quantum mechanics? Time independent Schrodinger equation (H Ψ = EΨ) and meaning of various terms in it. Significance of Ψ and Ψ2, Schrodinger equation for hydrogen atom in Cartesian coordinates (x,y,z). Need of polar coordinates, transformation of Cartesian coordinates (x,y,z) into polar coordinates (r,θφ). Radial and angular parts of the hydogenic wavefunctions (atomic orbitals) and their variations for 1s, 2s, 2p, 3s, 3p and 3d orbitals. (Only graphical representation), Radial and angular nodes and their significance. Radial distribution functions and the concept of the most probable distances with special reference to 1s and 2s atomic orbitals. Significance of quantum numbers, orbital angular momentum and quantum numbers mr and ms. Shapes of s, p and d atomic orbitals, nodal planes. Discovery of spin, spin quantum number (s) and magnetic spin quantum number (ms). Rules for filling electrons in various orbitals, Electronic configurations of the atoms. Stability of half-filled and completely filled orbitals, concept of exchange energy. Relative energies of atomic orbitals, Anomalous electronic configurations. Unit 2. Chemical Bonding and Molecular Structure Ionic Bonding :General characteristics of ionic bonding. Energy considerations in ionic bonding, lattice energy and solvation energy and their importance in the context of stability and solubility of ionic compounds. Statement of Born-Lande equation for calculation of lattice energy, Born-Haber cycle and its applications, polarizing power and polarizability. Fajan’s rules, ionic character in covalent compounds, bond moment, dipole moment and percentage ionic character. Covalent bonding :VB Approach :Shapes of some inorganic molecules and ions on the basis of VSEPR and hybridization with suitable examples of linear, trigonal planar, square planar, tetrahedral, trigonal bipyramidal and octahedral arrangements. Concept of resonance and resonating structures in various inorganic and organic compounds. MO Approach : Rules for the LCAO method, bonding and antibonding MOs and their characteristics for s-s, s-p and p-p combination of atomic orbitals, non- bonding combination of orbitals ,MO treatment of homonuclear diatomic molecules of 1st and 2nd periods (including idea of s-p mixing) and heteronuclear diatomic molecules such as CO, NO and NO+. Comparison of VB and MO approaches.

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t. Configuration: Geometrical and Optical isomerism. Strength of organic acids and bases: Comparative study with emphasis on factors affecting pK values. Hydration. Alkynes: (Upto 5 Carbons) Preparation: Acetylene from CaC2 and conversion into higher alkynes.trans nomenclature. Interconversion of Wedge Formula. oxymecuration-demercuration. butane and cyclohexane. Stereochemistry Conformations w. Fundamentals of Organic Chemistry Physical Effects. Ozonolysis. Newman.r. Aliphatic Hydrocarbons Functional group approach for the following reactions (preparations & reactions) to be studied in context to their structure. Unit 4. KMnO4. by dehalogenation of tetra halides. Cleavage of Bonds: Homolysis and Heterolysis. cis alkenes (Partial catalytic hydrogenation) and trans alkenes (Birch reduction). ethane. Concept of chirality (upto two carbon atoms). Threo and erythro. Aromaticity: Benzenoids and Huckel’s rule. D and L. Alkenes: (Upto 5 Carbons) Preparation: Elimination reactions: Dehydration of alkenes and dehydrohalogenation of alkyl halides (Saytzeff’s rule). Structure. Electromeric Effect. Reactions: formation of metal acetylides. Carbanions free radicals. Resonance and Hyperconjugation. ozonolysis and oxidation with hot alk. Kolbe’s synthesis. KMnO4) and trans-addition (bromine). Unit 5. Electronic Displacements: Inductive Effect. Reactive Intermediates: Carbocations. Diastereomerism and Meso compounds) . Addition of HX (Markownikoff’s and anti-Markownikoff’s addition). Alkanes:(Upto 5 Carbons). dehydrohalogenation of vicinal-dihalides. Enantiomerism. Preparation: Catalytic hydrogenation. Sawhorse and Fischer representations. from Grignard reagent. Reactions: Free radical Substitution: Halogenation. addition of bromine and alkaline KMnO4.Section B: Organic Chemistry-1 (30 Periods) Unit 3. CIP Rules: R/ S (for upto 2 chiral carbon atoms) and E / Z Nomenclature (for upto two C=C systems). hydroboration-oxidation. Reactions: cis-addition (alk. 5|Page . shape and reactivity of organic molecules : Nucleophiles and electrophiles. Wurtz reaction. cis .

D.Chemistry-1 (Atomic Structure. J. Lee: A new Concise Inorganic Chemistry. Estimation of oxalic acid by titrating it with KMnO4. General Organic Chemistry & Aliphatic Hydrocarbons) PRACTICALS Section A: Inorganic Chemistry . S. Peter Sykes: A Guide Book to Mechanism in Organic Chemistry. Estimation of Cu(II) ions iodometrically using Na2S2O3.Cl. Arun Bahl and B. 2. Marks: 50 Section B: Organic Chemistry 1. Section B: 1. B. S. tyrosine or any other amino acid) by paper chromatography (b) Identify and separate the sugars present in the given mixture by paper chromatography. 2.Volumetric Analysis 1. Detection of extra elements (N. Estimation of Fe(II) ions by titrating it with K2Cr2O7 using internal indicator. 6|Page .Br. Bonding. 5. 3. T. S. B. E L. L. Estimation of water of crystallization in Mohr’s salt by titrating with KMnO4. S. 2. Estimation of sodium carbonate and sodium hydrogen carbonate present in a mixture. Bahl : Advanced Organic Chemistry.I) in organic compounds (containing upto two extra elements) 2. Boyd: Organic Chemistry. Separation of mixtures by Chromatography: Measure the Rf value in each case (combination of two compounds to be given) (a) Identify and separate the components of a given mixture of 2 amino acids (glycine. Orient Longman. 3.SUGGESTED READINGS Section A: 1. Ellen Keiter and Richard Keiter : Inorganic Chemistry: Principles of Structure and Reactivity. I & II). glutamic acid. Pearson Publication. James E. 4. E. L. Morrison & R. Prentice Hall. Huheey. Chand 4. aspartic acid.S. R. Finar : Organic Chemistry (Vol. N. CHPP 101. I.

The formation and function of molecules depend on chemical bonding between atoms. Chemistry of life (Ch 2 Campbell) (6 Periods) The constituents of matter. Water and life The water molecule is polar.Paper 2-LSPT 101. Major events in the history of life. Structure of an atom. Model organisms for the genetic analysis. Evolutionary history of biological diversity (Ch 25 Campbell) (6 Periods) Early earth and the origin of life. Chemical context of living systems a. Introduction to concepts of biology (Ch 1 Campbell) (4 Periods) Marks: 100 Themes in the study of biology. Biological systems. Darwinian view of life and origin of species (Ch22. Developmental noise. 24 Campbell) (10 Periods) (Ch 25 Raven) (8 Periods) Darwin’s theory of evolution. The flow of genetic information from DNA to RNA to protein. The evolution of populations. Archaea d. Properties of water. Biology and everyday life b. Genetic approach to Biology (Ch 1 Griffiths) (8 Periods) Patterns of inheritance and question of biology. Phylogeny and the tree of life c. Detecting macromolecules of genetics. The energy level of electron. Classifying the diversity of life Kingdoms of Life –Prokaryotes. Distinction between Phenotype and Genotype Unit 2. Mechanism of Macroevolution.BIOLOGY-I (INTRODUCTION TO BIOLOGY) THEORY Unit 1. The process of Science. Methodologies used to study genes and gene activities. evolution and biodiversity a. Variation on Mendel’s Law. What makes carbon special? Properties of organic compounds 7|Page . Chemical reaction make or break chemical bonds b. Carbon and life (Ch 4 Campbell) (5 Periods) (Ch 3 Campbell) (5 Periods) Organic chemistry-the study of carbon compounds. Mechanism of speciation e. A closer look at cell. Eukaryotes. A closer look at ecosystem. The molecular basis of genetic information. Concepts of species. Ionization of water c. Genetic Variation.

coli. San Francisco. To perform quantitative estimation of protein using the Lowry's method. (2008) Biology 8th edition. New Delhi 3. 7. molar and standard solutions. To study the cytochemical distribution of nucleic acids and mucopolysaccharides with in cells/tissues from permanent slides. Determine the concentration of the unknown sample using the standard curve plotted.H. 2. Raven. phosphate buffers. 5.J. Protein have diverse structures and functions. Isolation of genomic DNA from E. 3. To perform gram staining of bacteria. serial dilutions Use of micropipettes Separation of A) amino acids B) chloroplast pigments by paper chromatography.H et al (2006) Biology 7th edition Tata McGrawHill Publications. Nucleic acids store and transmit hereditary information SUGGESTED BOOKS 1. NY LSPP 101. A. Marks: 50 To learn a) use of microscope b) principles of fixation and staining. 10. 8|Page . coli and estimate the culture density by turbidity method. 2. 9.F et al (2008) Introduction to Genetic Analysis.A. 8. 6. Griffiths. W. Draw a growth curve from the available data. Freeman & Co.d. Lipids are group of hydrophobic molecules. and Reece. N. Campbell. Carbohydrates act as fuel and building materials. To separate and quantify sugars by thin layer chromatography. Structure and function of biomolecules (Ch 5 Campbell) (8 Periods) Most macromolecules are Polymers.BIOLOGY-I (INTRODUCTION TO BIOLOGY) PRACTICALS 1. Pearson Benjamin Cummings. Preparation of Normal. 4. P. J. 9th edition. To raise the culture of E. B.

Discrete and Continuous Random variable. Functions and their graphs : polynomial. decreasing and. skewness. Differentiation. For instance. Examples of matrices inducing Dilation. Mean and Variance of Binomial. Curve Fitting. the Fibonacci sequence arising from branching habit of trees and breeding habit of rabbits. (20 Periods) Mesures of central tendency. Correlation and Regression. periodicity. (14 Periods) Points in plane and space and coordinate form. Unit 3. Intuitive idea of discontinuity. Examples of matrices arising in Physical. Mathematical Expectation. Sequences to be introduced through the examples arising in Science beginning with finite sequences. Use of methods of differentiation like Chain rule. 9|Page . sine. sin x. followed by concepts of recursion and difference equations. Elementary Probability and basic laws. Conception to be motivated through simple concrete examples as given above from Biological and Physical Sciences. kurtosis. Sum and Produce of matrices upto order 3. Product rule and Quotient rule. cos x. cosine. Hypothesis testing using standard normal variate. Biological Sciences and Biological networks. biological rhythms. Integration as reverse process of differentiation. Integrals of the functions introduced above. Series formulas for ex.Paper 3-MACT 303-MATHEMATICS AND STATISTICS Marks: 100 Unit 1. Emphasis on examples from Biological Sciences. Infinite Geometric Series. Intuitive idea of algebraic relationships and convergence. Step function. Rotation. Second order derivatives of above functions. Reflection and System of linear equations. log (1+x). continuity and limits. simple pendulum. muscular fibres etc. Poisson and Normal distribution. Unit 2. Measures of dispersion. cell division. Motivation and illustration for these functions through projectile motion. exponential and logarithmic functions. Simple observations about these functions like increasing. Sample mean and Sampling variance. (24 Periods) Sets.

1975) 3. 4. 2004. H. Druce : Advanced Biology Statistics. Edmondson and D. Bear: Understanding Calculus.SUGGESTED READINGS 1. New Delhi (1971. W. 1996. 10 | P a g e . John Wiley and Sons (Second Edition). A. Oxford University Press. graphical and application oriented approaches.Springer Verlag. John Wiley and Sons Inc. E. International Student Edition. Danial : Biostatistics : A foundation for Analysis in Health Sciences. 2003. Batschelet : Introduction to Mathematics for Life Scientists. Note: It is desirable that softwares should be used for demonstrating visual. 2. Narosa Publishing House. S.

agenda. S. distinct features of speech. R. narrative. letters. descriptive. 3.Biztaantra. memorandum. minutes. common errors to be avoided. distinct features of writing. Frank. G. notices. Selection of topic. Longman. Daniel G. differences between speech and writing. Writing as thinking: A guided process approach. Biztantra. manuals. Svartik: A comprehensive grammar of the English language. Heasely: Study Writing. Greenbaum. handbooks. 11 | P a g e . Additional Reference Books 5. 4. introductory. formal and informal writings. Steven E. Cambridge Univ. Quirk. Contemporary Business Communication. Englewood Cliffs. transitional and concluding paragraphs. coherence and cohesion. linguistic unity. M. Panley: “Technical Report Writing Today” .Paper 4/8-ENAT 101/201-TECHNICAL WRITING AND COMMUNICATION IN ENGLISH Marks: 100 Unit 1 Communication: Language and communication. Riordan & Steven A. A course in written English. developing the thesis. formal writings/reports. Hamp-Lyons and B. Biztantra: Technical Report Writing Today. 8th Edition (2004). 2. developmental. SUGGESTED READINGS 1. thesis statement. Riordan. Press. expository and argumentative writing. Daniel G. Unit 2 Writing Skills. London. Prentice Hall Reagents. L. Unit 3 Technical Writing: Scientific and technical subjects. 6. Pauley. Scot Ober. Leech and J. 5th Edition (2004). For academic and professional purposes.

Reference manual for Open Office available at: http://www. 1's Complement. Characteristics. System Security (virus/firewall) I-Tax. Addition and subtraction of binary numbers. Unicode. as they are freely downloadable.com/software/staroffice/ 12 | P a g e . BCD. router. I/O devices User Interface with the Operating System. memory hierarchy. Applications Problem Solving (10 Periods) Notion of algorithms. Reservations.openffice. switch. ASCII.Units of a computer. Types and generations of Computers Basic Computer Organization . 2's Complement.Paper 4/8-CSAT 101/201-COMPUTATIONAL SKILLS THEORY Computer Fundamentals (12 Periods) Marks: 100 Introduction to Computers: Characteristics of Computers. registers. Elements. server-client architecture Multimedia (4 Periods) Introduction. CPU. PHI. ALU. Networks terminology (4 Periods) Types of networks.sun. stepwise methodology of developing an algorithm.org Star Office available at: http://www. Fourth Edition. Note: Use of Open Office/Star Office is recommended. developing macros in spreadsheet General Awareness (4 Periods) IT Act. Fundamentals of Computers. Banking SUGGESTED BOOKS [1] V Rajaraman. System Tools Data Representation (8 Periods) Binary representation of integers and real numbers. Uses of computers.

Spreadsheet Handing. Presentation Software Marks: 50 4.CSAP 101/201-COMPUTATIONAL SKILLS PRACTICALS 1. Familiarizing with the Operating System. Defined projects will be done by the students and evaluated by the instructor. Creating a spreadsheet. basic functions and formulas. Control Panel. Document Preparation 3. Networking Configuration. Firewall setting 5. tables and graphs. entering and formatting information. creating charts. 2. Working with worksheets. 13 | P a g e .

moderate and weak electrolytes. Calculation of bond energy.Chemistry-2 (Thermodynamics. heat (q). Relationships between Kp. thermodynamic properties. q. Maxwell’s relations. degree of hydrolysis and pH for different salts. Unit 3. Gibbs – Helmholtz equation. thermodynamic equilibrium. state variables. Solubility and solubility product of sparingly soluble salts – applications of solubility product principle. common ion effect. Calculation of w. Chemical Equilibrium Free energy change in a chemical reaction. Thermodynamic derivation of the law of chemical equilibrium. factors affecting degree of ionization. Ionization of weak acids and bases. Le Chatelier’s principle. Concept of standard state and standard enthalpies of formations. 14 | P a g e . concept of heat and work. Criteria of spontaneity. changes in internal energy (∆U) and enthalpy (∆H) for expansion or compression of ideal gases under isothermal and adiabatic conditions for both reversible and irreversible processes. Calculation of work (w). Gibbs free energy and Helmholtz energy. pH scale. Kc and Kx for reactions involving ideal gases. Distinction between ∆G and ∆Gѳ. Ionic Equilibria Strong. Statement of Third Law of thermodynamics and calculation of absolute entropies of substances. Unit 2. Calculations of entropy change and free energy change for reversible and irreversible processes under isothermal and adiabatic conditions. First Law of thermodynamics. concept of entropy. ionization constant and ionic product of water. Salt hydrolysis-calculation of hydrolysis constant. bond dissociation energy and resonance energy from thermochemical data. Various statements of Second Law of thermodynamics.Paper 5-CHPT 202. Important principles and definitions of thermochemistry. Chemical Thermodynamics What is thermodynamics? State of a system. intensive and extensive variables. integral and differential enthalpies of solution and dilution. Variation of enthalpy of a reaction with temperature – Kirchhoff’s equation. degree of ionization. Equilibria & Functional Group Organic Chemistry-1) THEORY Section A: Physical Chemistry-1 Marks: 100 (30 Lectures) Unit 1. Buffer solutions. various types of systems and processes. ∆U and ∆H for processes involving changes in physical states.

KMnO4. Ester hydrolysis. carboxylic acid and esters. from acetylene. ROH. bromo and iodo-benzene case): from phenol. HX (Lucas test).Section B: Organic Chemistry-2 (30 Lectures) Functional group approach for the following reactions (preparations & reactions) to be studied in context to their structure. Unit 4. Reduction of aldehydes. Wittig reaction. halogenation and sulphonation. Reactions: hydrolysis. from diazonium salts. Aldehydes and ketones (aliphatic and aromatic): (Formaldehye. acetone and benzaldehyde) Preparation: from acid chlorides and from nitriles. Reactivity and Relative strength of C-Halogen bond in alkyl. Reactions – Reaction with HCN. Unit 5. Sandmeyer & Gattermann reactions. acetaldehyde . Phenols and Ethers (Upto 5 Carbons) Alcohols: Preparation: Preparation of 1 3 alcohols: using Grignard reagent.Tiemann Reaction. Preparation: from alkenes and alcohols. Clemensen reduction and Wolff Kishner reduction. benzyl. ketones. NaHSO3. Iodoform test. Unit 6. con. Aromatic hydrocarbons Preparation (Case benzene): from phenol. Alcohols. HNO3). vinyl and aryl halides. Unit 7. Meerwein-Pondorff Verley reduction. nitrile & iso-nitrile formation. Schotten – Baumann Reaction Ethers (aliphatic and aromatic): Cleavage of ethers with HI. Aryl Halides Preparation: (Chloro. Cannizzaro’s reaction. Houben – Hoesch Condensation. Benzoin condensation. halogenation and sulphonation. by decarboxylation. (Upto 4 carbons on benzene). SN1 and SNi) reactions. Reactions: Electrophilic substitution: Nitration. Aldol Condensation. Reimer . Side chain oxidation of alkyl benzenes (Upto 4 carbons on benzene). Pinacol-Pinacolone rearrangement. esterification. Gattermann-Koch Reaction. allyl. alk. dichromate. nitrite & nitro formation. Williamson’s ether synthesis: Elimination vs substitution. acid. Oppeneauer oxidation Diols: (Upto 6 Carbons) oxidation of diols. from benzene sulphonic acid. Benzyne Mechanism: KNH2/NH3 (or NaNH2/NH3). Reactions: With sodium. Reactions : (Case benzene) : Electrophilic substitution: nitration. Phenols: (Phenol case) Preparation: Cumene hydroperoxide method. NH2-G derivatives. Alkyl and Aryl Halides Alkyl Halides (Upto 5 Carbons) Types of Nucleophilic Substitution (SN2. Reactions (Chlorobenzene): Aromatic nucleophilic substitution (replacement by –OH group) and effect of nitro substituent. oxidation (with PCC. Friedel-Craft’s reaction (alkylation and acylation). 15 | P a g e .

Determination of integral enthalpy of solution of salts (KNO3. M. 4. Physical Chemistry 4th Ed. 2. determination of melting point and calculation of quantitative yields to be done. N. Determination of enthalpy of ionization of acetic acid. 5. University Chemistry 3rd Ed.Chemistry-2 (Thermodynamics. Recrystallisation. 2) Criteria of Purity: Determination of melting and boiling points. 3. Arun Bahl and B. NH4Cl). B. Section B: 1. G. S. L. G.SUGGESTED READINGS Section A: 1 Barrow. Finar : Organic Chemistry (Vol. W. I. Determination of enthalpy of neutralization of hydrochloric acid with sodium hydroxide. Study of the solubility of benzoic acid in water and determination of ∆H. Orient Longman. Peter Sykes : A Guide Book to Mechanism in Organic Chemistry. Morrison & R. 3. Narosa (2004). Castellan. E. Chand 4. 2. Mahan. 3. Narosa (1998). Prentice Hall. I & II). Boyd : Organic Chemistry. T. L. 3) Preparations: Mechanism of various reactions involved to be discussed. Determination of heat capacity of calorimeter for different volumes. 2. Section B: Organic Chemistry 1) Purification of organic compounds by crystallization (from water and alcohol) and distillation. Physical Chemistry Tata McGraw‐Hill (2007). Bahl : Advanced Organic Chemistry. Determination of enthalpy of hydration of copper sulphate. Equilibria & Functional Group Organic Chemistry-1) PRACTICALS Section A: Physical Chemistry Thermochemistry 1. CHPP 202. R. 6.4 dinitrophenylhydrazone of aldehyde/ketone 16 | P a g e Marks: 50 . H. S. B. S. (a) Bromination of Phenol/Aniline (b) Benzoylation of amines/phenols (c) Oxime and 2.

Molecular controls. Cell Membrane and Cell Wall The functions of membranes. Golgi body & Lysosomes Structures and roles. Cell size and shape. Signal peptide hypothesis. semiautonomous nature. chloroplast DNA ER. Light Microscopy. DNA packaging in eukaryotes. N-linked glycosylation. Peroxisomes and Glyoxisomes: Structures. composition. Fluorescence microscopy. Confocal microscopy. 16. Eukaryotic Cell components Unit 3. X-ray diffraction analysis Unit 2. Sample Preparation for light microscopy. euchromatin and heterochromatin. 13 Campbell) (8 Periods) Role of Cell division. Proteins synthesized within mitochondria. Phase contrast microscopy. functions in animals and plants and biogenesis Nucleus: Nuclear Envelope. (Ch 7 Campbell / Ch 15 Sheeler / Ch 3 Raven) (8 Periods) • • • • Unit 4. composition. Role of golgi in Olinked glycosylation. Symbiont hypothesis. mitochondrial biogenesis. composition. Membrane proteins and their functions.Paper 6-LSPT 202-BIOLOGY-II THEORY Cell and Cellular Processes Unit 1. mitochondrial DNA Chloroplast Structure. Cell secretion. marker enzymes. Models of membrane structure. Electron microscopy (EM)Scanning EM and Scanning Transmission EM (STEM).structure of nuclear pore complex. Prokaryotic and eukaryotic cells. Lysosome formation. Carbohydrates in the membrane. marker enzymes. Cell as a unit of Life (Ch 6 Campbell) (10 Periods) The Cell Theory. Selective permeability of the membranes. Techniques in Biology (Ch 1 Sheeler) (12 Periods) Marks: 100 Principles of microscopy. Cell Cycle: Interphase. Meiosis 17 | P a g e . chromatin. molecular organization. nucleolus and ribosome structure (brief).20 Sheeler) (22 Periods) Mitochondria: Structure. Semiautonomous nature. Cell Organelles • (Ch 15.19.18. The fluidity of membranes. Mitosis and Meiosis (Ch 12. Sample Preparation for electron microscopy. Faces of the membranes. Cell wall Unit 5. 17. Overview of Cell cycle.

Preparation of temporary mounts of striated muscle fiber 6. 9. 11. Study the effect of temperature. viruses. 10. 5. B. J. P.SUGGESTED BOOKS 1. John Wiley & sons NY LSPP 202-BIOLOGY-II PRACTICALS Marks: 50 1. To prepare temporary stained squash from root tips of Allium cepa and to study the various stages of mitosis.A. To study the structure of animal cells by temporary mounts-squamous epithelial cell and nerve cell. N. Raven. 2.E. Study of the photomicrographs of cell organelles 3. P and Bianchi. To prepare temporary stained preparation of mitochondria from striated muscle cells /cheek epithelial cells using vital stain Janus green. 8. Demonstration of dialysis of starch and simple sugar. 7. New Delhi 3. and Reece. Pearson Benjamin Cummings. Measure the cell size (either length or breadth/diameter) by micrometry. (2008) Biology 8th edition. Sheeler. 3rd edition. (2006) Cell and Molecular Biology. 2. D.H et al (2006) Biology 7th edition Tata McGrawHill Publications. To study the structure of plant cell through temporary mounts. Campbell. To study prokaryotic cells (bacteria). eukaryotic cells with the help of light and electron micrographs. 12. San Francisco. 4. Study the structure of nuclear pore complex by photograph (from Gerald Karp) 18 | P a g e . Study of plasmolysis and deplasmolysis on Rhoeo leaf. organic solvent on semi permeable membrane.

adolescents and elderly. constipation.adults. prevention and government programmes.their causes and dietary treatment. drug dependence and Aquired Immuno Deficiency Syndorme (AIDS). Classification. Causes of food spoilage. cough. Unit 5 Food hygiene Potable water. fevers. diarrhoea. treatment. their causes. Common aliments.Physiological considerations. Enzymes. Properties.Paper 7-LSPT 203.Iron. Food groups and the concept of a balanced diet. Classification. Life style related diseases. calcium.Definition and concept of health. phosphorus. Unit 3 18 Periods Nutritional Biochemistry Carbohydrates. preschool and school children. diabetes mellitus. pregnant and nursing mothers.Definition.cold. Iodine deficiency disorders. iodine.Fat-soluble and Water-soluble vitamins. symptoms. NUTRITION AND HEALTH THEORY Unit 1 Basic concept of food and nutrition Marks: 100 2 Periods Unit 2 12 Periods Functions of food Components of food-nutrients (Macro and micronutrients): their biochemical role and dietary sources. 24 Periods Major nutritional deficiency diseases. Lipids. nutrient needs and dietary pattern for various groups. Food adulteration Nutrition through the life cycle.sources and methods of purification Food and Water borne infections 4 Periods 19 | P a g e . iodine value and saponification value of lipids. Coenzymes Vitamins.smoking. selenium and zinc: their properties Unit 4 Health Introduction to health. and obesity.hypertension.their causes and prevention through dietary/lifestyle modifications.FOOD. infants. Social health problems. if any. Essential and Non-essential amino acids. Proteins .Definition. Vitamin A deficiency.Protein Energy Malnutrition. Structure and properties Significance of acid value. alcoholism. Iron deficiency anemia. their Structure and properties Minerals.

Berg. LSPP 203. Marks: 50 20 | P a g e . 2.Undertake computer aided diet analysis and nutrition counseling for different age groups. 6. Public Health Nutrition.FOOD. Mudambi. Manay MS. 6. 9. Gibney et al. 4. Pvt Ltd. Fourth Ed. J. 8. Text Book of Human Nutrition. 4. Fundamentals of Foods. and Reddy V. Ascorbic acid estimation in food by titrimetry. Lakra P.H Freeman and Co. Food Science. L. BAPPCO. 1998. OR Identify nutrient rich sources of foods. New Age International (P) Ltd. 5. Singh MD. 2007. First Ed. To determine absorbed oil content in fried foods. Tymoczko. Nutrition and Diet Therapy. 3. NUTRITION AND HEALTH PRACTICALS 1. Swaminathan M. 2008. Rao NP. Fifth Ed. Bamji MS. Project. 7. L. Estimation of calcium in foods by titrimetry. J. 2009. Textbook of Nutrition and Health. Fifth Ed. (2006). 10. 1986. Nutrition Science. New Age International Publishers Srilakshmi B. Hampl JS. and Stryer. MV. New Age International (P) Ltd. First Ed. Acadamic Pratibha. Estimation of lactose in milk. 2007. Preparation of temporary mounts of various stored grain pests. VI Edition. Srilakshmi B. SR and Rajagopal. 2002. Oxford & IBH Publishing Co. To detect adulteration in a) Ghee b) Sugars c) Tea leaves and d) Turmeric 2. Academic Excellence. 5. New Age International (P) Ltd. Shadaksharaswamy.. Handbook of Foods and Nutrition. study of nutrition labeling on selected foods. 2007. Food-Facts and Principles. Perspectives in Nutrition. Blackwell Publishing. 7. McGraw Hill. their seasonal availability and price. Wardlaw GM. 2004.SUGGESTED BOOKS 1. Poshan va swasthya ke mool siddhant (Hindi). 2007. M. 3. Biochemistry. W. Seventh Ed. 11. Jain P et al.

Immiscibility of liquids. Calculation of equilibrium constant from EMF data. deviations from Raoult’s law – non-ideal solutions. Concentration cells with transference and without transference.Chemistry-3 (Solutions. Unit 4. Distillation of solutions. ionic product of water. Types of electrodes. solvent extraction. Lever rule. Unit 3. Electrochemical series. Standard electrode potential. congruent and incongruent melting points (lead-silver. Unit 2. Applications of conductance measurements: determination of degree of ionization of weak electrolyte. Conductance Conductivity. Ionic mobility. solubility and solubility products of sparingly soluble salts. Potentiometric titrations qualitative treatment (acid-base and oxidation-reduction only). effect of impurity on partial miscibility of liquids. Solutions Thermodynamics of ideal solutions: Ideal solutions and Raoult’s law. Phase diagrams of one-component systems (water and sulphur) and two component systems involving eutectics. Nernst equation and its importance. Vapor pressure-composition and temperature-composition curves of ideal and non-ideal solutions. Gibbs Phase Rule and its thermodynamic derivation. Derivation of Clausius – Clapeyron equation and its importance in phase equilibria. 21 | P a g e . equivalent and molar conductivity and their variation with dilution for weak and strong electrolytes. Liquid junction potential and salt bridge. Kohlrausch law of independent migration of ions. components and degrees of freedom of a system. Azeotropes. ∆H and ∆S from EMF data. Nernst distribution law and its applications. Conductance. Electrochemistry and Functional Group Chemistry-2) THEORY Section A: Physical Chemistry-2 Marks: 100 (30 Lectures) Unit 1. Conductometric titrations (only acid-base). Phase Equilibrium Phases. hydrolysis constant of a salt. pH determination using hydrogen electrode and quinhydrone electrode. Electrochemistry Reversible and irreversible cells. calculation of thermodynamic properties: ∆G.Paper 9-CHPT 303. Transference number and its experimental determination using Hittorf and Moving boundary methods. criteria of phase equilibrium. FeCl3-H2O and Na-K only). Principle of steam distillation. Concept of EMF of a cell. Measurement of EMF of a cell. Thermodynamics of a reversible cell. Partial miscibility of liquids: Critical solution temperature.

absolute configuration of Glucose and Fructose. Hofmann Bromamide reaction. dyes. Amines and Diazonium Salts Amines (Aliphatic and Aromatic): (Upto 5 carbons) Preparation: from alkyl halides. Glucose and Fructose (open chain and cyclic structure). Electrophilic substitution (case aniline): nitration. Anhydrides. Reformatsky Reaction. Schotten – Baumann Reaction. Diazonium salts: Preparation: from aromatic amines. Reactions: conversion to benzene. Reactions: Hell – Vohlard . ascending and descending in monosaccharides. Keto-enol tautomerism Reactions: Synthetic uses of ethylacetoacetate (preparation of non-hetero molecules having upto 6 carbon). 22 | P a g e . cellobiose. maltose. Carboxylic acid derivatives (aliphatic): (Upto 5 carbons) Preparation: Acid chlorides. Carbylamine test. sulphonation. Active methylene compounds: Preparation : Claisen ester condensation. Carbohydrates: Classification. Unit 7. Gabriel’s Phthalimide synthesis. Unit 5. Structure of disacharrides (sucrose. Unit 6.Section B: Organic Chemistry-3 (30 Lectures) Functional group approach for the following reactions (preparations & reactions) to be studied in context to their structure. bromination.Zelinsky Reaction. Reactions: Comparative study of nucleophilicity of acyl derivatives. and General Properties. Perkin condensation. Mutarotation. Determination of configuration of monosaccharides. Carboxylic acids and their derivatives Carboxylic acids (aliphatic and aromatic) Preparation: Acidic and Alkaline hydrolysis of Esters. Hinsberg test. Unit 8. with HNO2. lactose) and polysacharrides (starch and cellulose) excluding their structure elucidation. Reactions: Hofmann Vs Saytzeff elimination. phenol. Esters and Amides from acids and their inter-conversion.

like aerated drinks. John Wiley & Sons 10. b) Preparation of buffer solutions: (i) Sodium acetate-acetic acid (ii) Ammonium chloride-ammonium hydroxide Measurement of the pH of buffer solutions and comparison of the values with theoretical values. 5. pH measurements a) Measurement of pH of different solutions. L. Treichel.: New Delhi (2009). Morrison & R. T. R. I. Macmillan Publishing Co. G. Mahan. Jerry March :Advanced organic Chemistry.SUGGESTED READINGS 1. 4. Finar :Organic Chemistry (Vol. shampoos and soaps (use dilute solutions of soaps and shampoos to prevent damage to the glass electrode) using pH-meter. B. Orient Longman. 8.Chemistry-3 (Solutions. R. R. S. P. 2. & Townsend. (1985) General Chemistry 5th Ed. G. J. 11. Conductance. I. Graham Solomon’s :Organic Chemistry. Arun Bahl and B. C. Physical Chemistry 4th Ed. W.. Narosa (1998). S.: New York (1985). fruit juices. Boyd :Organic Chemistry. H. 3. I & II)E. M. T. B. 2. Chand CHPP 303. 6. 9.Petrucci. H. 7. General Chemistry Cengage Learning India Pvt. S. N. Bahl : Advanced Organic Chemistry. Peter Sykes :A Guide Book to Mechanism in Organic Chemistry. Distribution Study of the equilibrium of one of the following reactions by the distribution method: Marks: 50 23 | P a g e . University Chemistry 3rd Ed. Narosa (2004). Lt d. M. John Wiley and Sons. Prentice Hall. Castellan.Kotz. J. Electrochemistry and Functional Group Chemistry-2) PRACTICALS Section A: Physical Chemistry 1. W. Barrow. Physical Chemistry Tata McGraw-Hill (2007).

(f) Preparation of methyl orange.Section B: Organic Chemistry Preparations: Mechanism of various reactions involved to be discussed. Recrystallisation. 24 | P a g e . (a) Nitration of Nitrobenzene (b) Preparation of carboxylic acid by alkaline hydrolysis of ester/amide. determination of melting point and calculation of quantitative yields to be done. (c) Oxidation of alcohol/aldehydes/hydrocarbons to carboxylic acid (d) Osazone from glucose/fructose (e) Amides and anilides from carboxylic acid.

Growth. Ecology and distribution (with reference to distribution in Indian peninsula). Range of thallus organization and reproduction.Paper 10-LSPT 304. 7. Ecology and distribution. and on animals (with special reference to: Tuberculosis and Cholera). Important classes in relation to Applied Phycology listed below Cyanophyceae. Symptoms. Economic importance. 8. Structure of DNA virus (bacteriophage T4). Unit 4. (Ch 29. asexual and recombination. Viruses Marks: 100 (2 Period) (Ch 13 Tortora et al.) 25 | P a g e . 18 Prescott) (11 Periods) Discovery. 9. 1945). Wall composition. Ecology and significance (Physarum as an experimental tool). 13 Sharma) (12 Periods) General characteristics. Detailed study of two diseases each on plants (with special reference to: Crown gall and Citrus canker). Reproduction. Fungi and their allies (24 Periods) General characteristics.Fucus and Kelps Rhodophyceae. Reproduction and spores. Life cycle of Stemonitis /Physarum. Cell structure. / Ch 16. 4. transmission and management of diseases caused by bacteria and mycoplasma on plants.Porphyra and Gracilaria Unit 5. Ecology and distribution. 22. Heterokaryosis and parasexuality. 24 Prescott) (11 Periods) Discovery of bacteria. Physiochemical and biological characteristics. and Dengue and AIDS Unit 3. Nutrition.Chlamydomonas. Lytic and Lysogenic cycle. transmission and management of diseases caused by viruses in plants and in animals-with special reference to Mosaics and Vein clearing. Comparison of Archaea and Eubacteria. / Ch 21. Algae (Ch 2. Mycoplasma. Oncogenic virus (HIV). Prokaryotes (Ch 11 Tortora et al. Basic criteria used in classification. 12. General structure. 17. Protoplasts and Sphaeroplasts) Nutrition. Wall-less forms (L-forms.BIODIVERSITY-I MICROBES THEORY Unit 1. Replication.Volvox. Alexopoulos et al.Chlorella Bacillariophyceae-Diatoms Phaeophyceae. Introduction to microbial world and to study its diversity Unit 2. Basic criteria used in classification (Fritsch. Classification (including Baltimore’s). 23. RNA virus (TMV). (Ch 1 Webster and Weber) Myxomycetes: General characteristics. Range of thallus organization. Reproduction–vegetative. Symptoms.Nostoc Chlorophyceae.

C. B. 5 Webster and Weber) General characteristics. Claviceps and its telomorphs (Ascomycetes) Puccinia. Sherwood.K. Sahoo Dinabandhu. Narosa Publishing House. R. Farming the ocean Aravali International. Vikas Publishing House Ltd. Woolverton. Delhi 8.. John Wiley & Sons. Ecology and significance. Thallus organization. Reproduction. (2007) Introduction to Fungi (3rd Edition) Cambridge Univ.J. transmission and management of fungal diseases on plants. U. 2000. New Delhi. 5. 10th edition Microbiology: An Introduction.R. Sharma. USA.5. G. Linda. Inc.W. Webster J. Reproduction.8. Sharma.J. 6. Life cycle of Rhizopus (Zygomycetes). (Sharma 2005) SUGGESTED BOOKS 1. Tata McGraw Hill Publishing Co. (Basidiomycetes) and Alternaria (Deuteromycetes) Penicillium (Anamorphic fungi).14. (1996) Introductory Mycology. I & II) The structure and reproduction of the Algae. Tortora. Fungi and Allied Organisms. and Blackwell. Mims. Joanne. 4. 8th edition (2011) McGraw Hill. Funke.S.) Associations of Fungi: Lichens: General account. New Delhi. (Ch 4. (2010). 45 (Vol. Case. Pearson. Paress.19. C. Symptoms. OP (2002) Textbook of Thallophytes. Prescott's Microbiology by Willey. and Weber. 2.17.20 Alexopoulos et al. C. PD (2005). Ecology and significance.11.L. 3. Delhi 26 | P a g e . Two diseases each on plants (with special reference to Rust of wheat and Early blight of potato).2. (Ch 7.E. Reproduction. 1935. Thallus organization. Mycorrhizae: General account and its significance.Oomycetes: General characteristics. Chris. Agaricus. M. 7. Alexopoulos.W. and on humans (with special reference to Candidiasis and Dermatophytes to be studied in detail). Fritsch F. Life cycle of Albugo.22 Webster and Weber / Ch 1.

and permanent slides. Study of fungi through temporary preparations and permanent slides: Penicillium. Asexual and sexual structures through sections/ tease mounts and permanent slides. 8. 9. 27 | P a g e . Polysiphonia. Infected specimens of any plants infected with mosaic virus and vein clearing virus. 5. Study of phaneroplasmodium from specimens or photographs. Study of mycorrhizae through photographs. binary fission. Bacteria: Study of bacteria through permanent slides (cocci. Puccinia. 6. and Alternaria. Study of Rhizopus through temporary preparations. bacteriophage and HIV. Viruses: EM/ Model of TMV. Study of symptoms of plants infected with rust and early blight. Study of algae through permanent slides: Volvox. Study of habit and sporangia of Physarum/ Stemonitis from temporary mounts. Fucus. w. Specimens/ photographs and permanent slides of root nodules. Photographs of Actinomycetes. 2. spirilli).BIODIVERSITY-I MICROBES PRACTICALS Marks: 50 1. 7.LSPP 304. 3. 4. EM of bacterial cell (surface details and sectional view). EM of endospore. Study of lichens from permanent slides and specimens. conjugation. bacilli. Oedogonium. Nostoc. Study of symptoms of plants infected with Albugo.m. EM of heterocyst. Study Agaricus (through specimens and permanent slides only).

Fox & Barnes) (3 Periods) General characters of Echinodermata. Ruppert. Aves: (Ch 34. Fox & Barnes) (3 Periods) General characters and canal system in Porifera Unit 3. Evolution of Man. 12 J Z Young) (5 Periods) Unit 13. Parasitic adaptations Unit 6. Mollusca (Chapter 12. Arthropoda General characters. Fox & Barnes) (3 Periods) General characters of Helminthes. Life cycle of Taenia solium Unit 5. Barnes) (3 Periods) General characters of Nemethehelminthes. 14 J Z Young) (5 Periods) Amniotes. 22 & 24 J Z Young) (7 Periods) Early evolution of mammals.Paper 11-LSPT 305. Origin and evolutionary radiation of reptiles Unit 14. Reptilia (Ch 34. Radiata (Chapter 7. Life cycle of Plasmodium Unit 2. Mammalia (Ch 34. Water Vascular system in Starfish. Aceolomates (Chapter 10. Flight adaptations Unit 15. Ruppert. 15&17 J Z Young) (5 Periods) The origin of birds. Pisces Osmoregulation. Fox & Barnes) (3 Periods) General characters of mollusca. Pearl Formation Unit 9. Fox & Barnes) (3 Periods) General characters of Annelida . Unit 8. Porifera (Chapter 5. Fox & Barnes) (4 Periods) Unit 7. Coelomate Deuterostomes (Chapter 28. Unit 10. Protista (Chapter 3. Campbell & Reece/ Ch. J Z Young) (6 Periods) (Ch. Ruppert. Ruppert. Migration of Fishes Unit 12. Campbell & Reece/ Ch. Coelomate Protostomes (Chapter 13. 28 | P a g e . Protochordata Salient features Unit 11. Ruppert. Fox & Barnes) (4 Periods) General characters of Protozoa. Primates. Amphibia Origin of tetrapods (Ch 2 and 3. Fox & Barnes) (3 Periods) General characters of Cnidarians and polymorphism Unit 4. Pseudocoelomates (Chapter 11. J Z Young) (2 Periods) (Ch 5. Social life in insects. Ruppert.BIODIVERSITY-II ANIMALS THEORY Marks: 100 Unit 1. Metamerism. Ruppert. (Chapter 16. Ruppert. Campbell & Reece/ Ch.

(2004). and typhlosolar intestine. (Singapore) Pvt. of arm of Starfish. 6. . Amphioxus. and Johnson. Sycon. Naja. Function and Evolution. Dentalium. Chiton. V. Squirrel and Bat. A functional Evolutionary Approach 7th Edition. Labeo. R. and Antedon. Barnes. Millipede. USA. duck. (1992). 29 | P a g e Marks: 50 . Raven. Campbell & Reece (2005). Pristis. Sea anemone and Ascaris(male and female). Beetle. Dissections Digestive and nervous system of Cockroach. Taenia. . Viper. Temporary mounts Septal & pharyngeal nephridia and ovary of earthworm. Noctiluca. gizzard. Biology. Invertebrate Zoology. Aphrodite. Dissections Afferent Branchial System of Scoliodon 7. Nereis. G. 3. Icthyophis/ Uraeotyphlus. Rhacophorus Draco. Vertebrates Comparative Anatomy. 4. Hermitcrab. Tata McGraw Hill Publications. Peripatus. Petromyzon. any three common birds-(Crow. H. Metridium. Limulus. Centipede. 2. Leech. model of Archaeopteryx. Owl). S. Chordata 5. Temporary mounts Unstained mounts of Placoid scales. Physalia. Paramecium. (2002). Study of Permanent Slides: Cross section of Sycon. 6th edition. Daphnia. New Delhi. P. Asterias.D. Uromastix. Tubipora. Kardong. Tata McGraw Hill Publishing Company. New Delhi. 4. Study of following specimens: Euglena. LSPP 305. Fox and Barnes (2006) Invertebrate Zoology. Bipinnaria and Pluteus larva. Octopus. Study of following specimens Balanoglossus. B. T. T. 2.BIODIVERSITY-II ANIMALS PRACTICALS Non-Chordata 1. Ascaris. Pearson Education. Saunders College Pub. K. Salamander. 5. Ruppert. Thomson Books/Cole 3. S. Hippocampus.SUGGESTED BOOKS 1. Biology. of Earthworm passing through pharynx. Ltd.

HPLC and GC-MS Nuclear Magnetic Resonance Spectroscopy (NMR) Atomic Force and Scanning Electron Microscopy (AFM and SEM) Electrochemistry Molecular Modeling and Chemical Databases 30 | P a g e . diagnosis and treatment Ageing. genetic basis. Treatment How pathogenesis relates to symptoms. Systemic Lupus Erythematosus (SLE)) Cancer. 18. Morphological changes. 20 Davidson.W. Viral. Di George’s Syndrome. 14. 22 Hage and Carr) (20 Periods) Brief and relevant description of the following Wet techniques in Analytical Chemistry Spectroscopic techniques such as UV Chromatography Methods such as LC. Down Syndrome) Immunological diseases (Autoimmune hemolytic anemia (AHA).Theories.Paper 12-LSPT 306.) (6 Periods) Descriptive and analytical statistical methods /tools for evaluation of health of various human groups of interest Interpretation of statistical data in scientific publications Unit 3. 14 Robbins. Hypertension.Leishmaniasis. 17. Hepatitis. Statistical Analysis and Interpretation (Ch-14 Daniel W. Poliomyelitis. Ch 2. 3 7. 21. Hashimoto’s disease. Biomedical basis of Disease 16 Weinberg) Marks: 100 (Ch 3. Clinical implications Diseases impacting on Western versus developing societies Social and economic factors of disease including role of health services and other organizations Unit 2. Metastasis. Protozoan.INTRODUCTION TO MEDICAL DIAGNOSTICS THEORY Unit 1. Analytical Technology (Ch-1.Nature/ types. (22 Periods) Cause and molecular or cellular progression of key diseases • • • Infectious (Bacterial-Tuberculosis. Typhoid. Ch 7. Malaria) Inherited/genetic diseases (Diabetes.AIDS. Anthrax.

3rd edn. Stryer L.ECG. 4. Echo.Unit 4. biochemistry. 8. 4. (2010) Analytical Chemistry & Quantitative Analysis.W. Ultrasound SUGGESTED BOOKS 1. Blood platelet count by hemocytometer. Ultrasound.E. (2006) Textbook of Medical Physiology 11th edn. 7. 12. and Hall J. CT. 5. Estimation of Haemoglobin content of blood using Sahli’s haemoglobinometer. Robbins S. Lippincott Williams &Wilkins. 3. Prentice Hall 6.M.: Davidson’s Principles & Practice of Medicine: A textbook for students and doctors’ 14th Edition. Macleod J. Enumeration of RBC. Physiological Measurements: Blood Pressure (normal & under stress) and Temperature. Churchill Livingstone.. Determination of Erythrocytic Sedimentation Rate.C. John Wiley & Sons. Determination of bleeding and blood coagulation time. (1974) Pathological basis of Disease. Tymoczko J. (2009) Biostatistics-A Foundation for Analysis in the Human Health. X-ray. 2. Saunders 5. haematology and microbiology laboratories. and Helms C. (Students would be required to interpret the images under various pathological conditions) 31 | P a g e . Hage D S and Carr J D. Detection of abnormal constituents in urine. Berg J. CT. 2.E. Daniel W. Freeman & Co. Brant W. Testing of blood glucose using glucometer /colorimeter 7. 9th Edition. Determination of total sperm count (million/ml) and motility grading (WHO grading) from Rat 10. MRI. Introduction to medical imaging-X-ray. DLC) using haemocytometer. cholesterol by kits 9.H. Diagnostic Methods (Ch-11 Guyton. W.A. Demonstration of Electrocardiogram or ECG 11. WBC (TLC. Ch-1 Brant. and apply some of these in the laboratory Theoretical Knowledge. (2007) Fundamentals of Diagnostic Radiology. 6.L. MRI. Ch-4 Stryer) (12 Periods) Outline methods used in hospital histopathology.INTRODUCTION TO MEDICAL DIAGNOSTICS PRACTICALS Marks: 50 1. W B Saunders Company 3. Clinical estimation of glucose. Biochemistry.. Guyton A. 5th edn. LSPP 306.L.

block elements. organic and environmental chemistry. Allotropy in C. Causes of deviation.block elements.and p. Hydrometallurgy. Collision cross section.Block Elements Periodicity in s.Paper 13-CHPT 404: Chemistry-4 (Chemistry of s & p block elements. w. NH2OH) Oxoacids of P.and p. S and Cl Halides and oxohalides: PCl3. Critical phenomena. Fe. Andrews isotherms of CO2. N3H. diagonal relationship and anomalous behaviour of first member of each group. N2H4. Parting process. bonding and their important properties like oxidation/reduction. ionization enthalpy. PCl5.r. Kinetic Theory of Gases Postulates of Kinetic Theory of Gases and derivation of the kinetic gas equation. atomic and ionic size. van der Waals equation of state for real gases. Zn): electrolytic. Ni.and p. acidic/basic nature of the following compounds and their applications in industrial. oxidative refining. covalent and interstitial). collision diameter and mean free path of 32 | P a g e . and Alred-Rochow scales). Methods of purification of metals (Al. Ellingham diagrams for reduction of metal oxides using carbon as reducing agent. Deviation of real gases from ideal behaviour. Most probable. Kroll process. collision frequency. structure and properties with respect to stability of hydrides of p. electronegativity (Pauling. Cu. and P. Pb. collision number.Block Elements Hydrides and their classification (ionic. Unit 2. inert pair effect. Unit 3. General Principles of Metallurgy Chief modes of occurrence of metals based on standard electrode potentials. Structure. Oxidation states with reference to elements in unusual and rare oxidation states like carbides and nitrides). average and root mean square velocities (no derivation). Mullikan. electronic configuration. S. Compounds of s. critical constants and their calculation from van der Waals equation. compressibility factor. SOCl2 and SO2Cl2 Section B: Physical Chemistry-3 (30 Lectures) Unit 1. van Arkel-de Boer process and Mond’s process. Concept of multicentre bonding (diborane).t. States of Matter and Phase Equilibrium) THEORY Section A: Inorganic Chemistry-2 Marks: 100 (30 Lectures) Unit 1. Ti. Maxwell Boltzmann distribution laws of molecular velocities and molecular energies (graphic representation – derivation not required) and their importance. Hydrides of nitrogen (NH3. Temperature dependence of these distributions. s. Boyle temperature derivation not required).

B. Derivation of integrated rate equations for zero. Structures of NaCl. 5.: New York (1985). W. X–Ray diffraction by crystals. H. Comparison of the two theories (qualitative treatment only). 3. Defects in crystals.Petrucci. Solids Forms of solids. G.S. Cotton & G. Unit 4. Glasses and liquid crystals. E. first and second order reactions (both for equal and unequal concentrations of reactants). Half–life of a reaction. D. Lee :A New Concise Inorganic Chemistry. Viscosity of gases and effect of temperature and pressure on coefficient of viscosity (qualitative treatment only). 2. KCl and CsCl (qualitative treatment only). 6. Shriver and P. F. Laws of Crystallography . Narosa (1998). University Chemistry 3rd Ed. Kotz. 4. Unit 2.A. 9. Bravais lattice types and identification of lattice planes. 8. D. Symmetry elements. General Chemistry Cengage Learning India Pvt. General methods for determination of order of a reaction. J. B. J.Law of constancy of interfacial angles. P. M.: New Delhi (2009). John Wiley. Atkins : Inorganic Chemistry. R. G. Effect of temperature. Oxford University Press. (1985) General Chemistry 5th Ed. Ltd. J. M. Physical Chemistry 4th Ed.L.. Chemical Kinetics The concept of reaction rates. 33 | P a g e . Liquids Surface tension and its determination using stalagmometer. F. Effect of temperature on surface tension and coefficient of viscosity of a liquid (qualitative treatment only) Unit 3. & Townsend. Viscosity of a liquid and determination of coefficient of viscosity using Ostwald viscometer. Miller indices. Barrow. Narosa (2004). crystal systems. 7. Treichel. unit cells. Gary Wulfsberg : Inorganic Chemistry. SUGGESTED READINGS 1. Wilkinson :Basic Inorganic Chemistry. Mahan. Castellan. H. Viva Books Pvt. Ltd. Theories of Reaction Rates: Collision theory and Activated Complex theory of bimolecular reactions.molecules. W. Concept of activation energy and its calculation from Arrhenius equation. C. Physical Chemistry Tata McGraw-Hill (2007). pressure. Order and molecularity of a reaction. Macmillan Publishing Co. R. Law of rational indices. catalyst and other factors on reaction rates. Bragg’s law.

) Section B: Physical Chemistry (I) Surface tension measurement (use of organic solvents excluded) a) Determination of the surface tension of a liquid or a dilute solution using a stalagmometer. b) Study of the variation of surface tension of a detergent solution with concentration. Bi3+. Cd2+. SO42-. c) Study of the variation of mutual solubility temperature with concentration for the phenol water system and determination of the critical solubility temperature. Sr2+. C2O42-. Br–. SO32 –.CHPP 404. Al3+. Ba2+. Anions : CO32– . K+. PO43-. CH3COO–. 34 | P a g e Marks: 50 . Cu2+. Pb2+. S2 –. Ni2+. NO3–. Co2+. b) Determination of the critical solution temperature and composition of the phenol water system and study of the effect of impurities on it. (II) Viscosity measurement (use of organic solvents excluded) a) Determination of the relative and absolute viscosity of a liquid or dilute solution using an Ostwald’s viscometer. Cl–. Mn2+. Sn2+. Ag+. NO3–. b) Study of the variation of viscosity of an aqueous solution with concentration of solute. Fe3+. F(Spot tests should be carried out wherever feasible. Ca2+. States of Matter and Phase Equilibrium) PRACTICALS Section A: Inorganic Chemistry Semi-micro qualitative analysis using H2S of mixtures not more than four ionic species (two anions and two cations and excluding insoluble salts) out of the following: Cations : NH4+. Zn2+. I–. S2O32 –. BO33-. (III) Phase equilibria a) Construction of the phase diagram of a binary system (simple eutectic) using cooling curves.Chemistry-4 (Chemistry of s & p block elements. Cr3+.

Translation (Prokaryotes and eukaryotes): features of genetic code and deciphering. 3 Russell / Ch 14 De Robertis) (18 Periods) DNA: Miescher to Watson and Crick. Griffith’s and Avery’s transformation experiments. Apoptosis (Cell Death) & Cell Renewal (Ch 17 Cooper et al) (7 Periods) Mechanism of apoptosis. Transcription (Prokaryotes and Eukaryotes): Ch 14. DNA structure. Telomere shortening and Human Cancer.various types. tRNA.Paper 14-LSPT 407. aminoacyl tRNA synthetases.MOLECULAR BIOLOGY THEORY Unit 1. replicating the 5´end of linear chromosome including replication enzymes. 15 Klug and Cummings) (Ch 5. universality of genetic code and exceptions in some systems. initiation. Role of apoptosis in human diseases Stem Cells and Maintenance of adult tissues Unit 5. and in Eukaryotes Unit 4. ds-DNA. Charging of tRNA. Unit 3. RNA polymerase. elongation and termination of polypeptides. 6 Russell / Ch 20 De Robertis / (20 Periods) Types of structures of RNA (mRNA. Genes and Cancer. Hershey-Chase bacteriophage experiment. Chemicals and Radiations as carcinogen 35 | P a g e . Ǿ (theta) mode of replication. semi–conservative. types of genetic material. types of DNA. Genetic material: Marks: 100 (Ch 2. Cancer (Ch 22 Russell) (7 Periods) Relationship of the cell cycle to cancer. Proteins involved in initiation.historic perspective. DNA replication (Prokaryotes and eukaryotes): bidirectional replication. semi discontinuous RNA priming. elongation and termination of RNA chains. replication of linear. Regulation of gene expression (Ch 19 Russell) (8 Periods) Prokaryotes:Lac operon and Tryptophan operon . rRNA). Unit 2. Intrinsic and extrinsic pathways.

Spencer. Klug. (2009). XI Edition. iGenetics. 4. Hausman. De Robertis. W. J. Benjamin Cummings. 4. (2009). 3.. G. Russell. 5.E.S. Cooper. E. Benjamin Cummings.MOLECULAR BIOLOGY PRACTICALS 1.P. P. Marks: 50 Study of special chromosomes (polytene & lampbrush) either by slides or photographs... C.(2008) Lippincott Williams and Williams (Sixth Edition). III Edition. 3.R.A Molecular Approach. 6.M. To make temporary squash preparation of grasshopper testis and study the various stages of meiosis 36 | P a g e . Preparation of barr body (sex chromatin) Study DNA packaging by micrographs. The Cell: A molecular approach. M. Cell and Molecular Biology. Concepts of Genetics.A. (2009) ASM Press and Sinauer Associates (Fifth Edition). Preparation of the karyotype and ideogram from given photograph of somatic metaphase chromosome. LSPP 407.D. Cummings. Preparation of polytene chromosomes from dipteran larva. 2. 2. R.SUGGESTED BOOKS 1.

W. Tata McGraw Hill Publishers. Classification. Introduction Marks: 100 (Ch 29 Raven et al. Reece) (7 Periods) Different types of tissue. Unit 4. et al. Gymnosperms (Ch 29 Raven et al. family. Unit 5. Angiosperms (i) (Ch 29 Raven et al. Study of vegetative and reproductive structures (including anatomical details) in Cycas & Pinus./ Ch 29. legumes (Gram & Groundnut). (2004) Plant Systematics: Theory and Practice 2nd edition. its application with reference to identification of Solanaceae. Reece) (11 Periods) Classification. Oxford & IBH Publishing Co. et al..H. P. Reece) (22 Periods) Structure of flower. part used and important uses) with reference to cereals (Wheat & Rice).) (9 Periods) Classification. characteristic features of different groups. Singh.H. spices (Black pepper & Fennel). stem & leaf (monocot & dicot). Asteraceae and Poaceae. (ii) SUGGESTED BOOKS 1. 3. their organization into root. 37 | P a g e . Special reference to Bentham & Hooker’s system of classification. (2006) Biology 7th edition. Unit 3./ Ch 30 Campbell.Paper 15-LSPT 408. Raven. Concept of stele and its evolution. ND 2.BIODIVERSITY-III PLANTS THEORY Unit 1. / Ch 30 Campbell. types of inflorescence. Unit 2. Adaptations to land habit.l) (11 Periods) Classification. Delhi. Study of vegetative and reproductive structures (including anatomical details) in Marchantia & Funaria. timber (Teak & Pine). Brassicaceae. Bryophytes (Ch 29 Raven et al. Equisetum & Pteris. Economically important plants (botanical name. An Introduction to Plant Biology 3rd edition. (2003) Botany. beverages (Tea & Coffee). D. medicinal (Rauvolfia & Digitalis) plants. 35 Campbell. characteristic features of different groups. Study of vegetative and reproductive structures (including anatomical details) in Selaginella (with concept of heterospory and seed habit). Freeman and Co. fibres (Cotton & Jute). Jones and Barlett Publishers. Phylogenetic & Modern system). Apogamy and Apospory. Pteridophytes (Ch 29 Raven et a. (2005) Biology of Plants 7th edition. characteristic features of different groups. Mauseth. Raven P. H. G. J. 4. Importance of Cultivated plants: Centres of origin of cultivated plants. Natural. fatty oil (Mustard & Linseed). Four systems of classification (Artificial.

& T. Permanent slides showing antheridial and archegonial heads.S. Megasporphyll. L. V. Kochhar. Cycas: Morphology ( coralloid roots. sporangiophore. operculum. & Reece. sporophyll.M. Permanent slides showing fern prothallus. microsporophyll & microspores.S. Equisetum: Morphology. T. spores. 7.S. sclerenchyma. L. spores. Funaria: Morphology. Selaginella: Morphology. W.A.S.S.L.S. W. 3.M. 5. Pearson Education. Pteris: Morphology.S. W. V. T. J. sporangia. Study of plant tissues (parenchyma.S. S.S. sporophyte. W. Angiosperms: Study of floral characters of the following families for their identification according to Bentham & Hooker’s system of classification: • • • • Solanaceae: Solanum / Withania Brassicaceae: Brassica / Alyssum Asteraceae: Calendula / Helianthus Poaceae: Triticum / Avena 11. stem through internode. Mac Millan Publishers India Ltd.S.S. Study of economically important plants as mentioned in the theory syllabus: • Cereals: Wheat & rice –Study through herbarium specimens and microchemical tests. V. LSPP 408. collenchyma. W.M. Ovule. 9.S. W. Permanent slides showing T. spores (wet & dry).M.M. Inc.M. Marchantia: Morphology of thallus (vegetative and with gemma cup). mega.M.S. and Dorling Kindersely Publishing. bulbil. microsporophyll. peristome teeth and spores. Inc. rhizoids. male cone. 6.M. gemmae. W. leaflet Male cone. W. capsule. 38 | P a g e .B. leaf. rachis. leaf with ligule. Permanent slide showing T. 2. needle. rachis. rhizoids.M. stem and L.BIODIVERSITY-III PLANTS PRACTICALS Marks: 50 1.M. L. strobilus. 4.and microsporangia.S. 6. Pinus: Morphology (long and dwarf shoots).5. thallus through gemma cup. (2005) Biology. Permanent slide showing L. W. • Legumes: Gram and peanut –Study through herbarium specimens and microchemical tests. Morphology of male & female thallus.S. V.S. T. strobilus. coralloid root and L. Campbell N.M. Male cone. W. leaf). V. (2009) Economic Botany: In the Tropics 3rd edition.S. stem.S. protonema. 8. W. strobilus. xylem & phloem) through permanent slides only. Permanent slides showing T.

Multiple Sequence Alignment (MSA). Nucleotide Database. Unit 5. Biological Databases. Blocks of Amino Acid Substitution Matrix (BLOSUM). 8 Ghosh and Mallick / Ch 6 Pevsner) (10 Periods) Introduction. Percent Accepted Mutation (PAM). Biological Database Retrieval System. Classification format of Biological Databases. (Ch 8 Ghosh and Mallick / Ch 7 Pevsner) (8 Periods) Methods of Phylogeny. Sequence Alignments (Ch 6. Database Retrieval Tool. Basic local alignment search tool (BLAST). Consistency of Molecular Phylogenetic Prediction. (Ch 3 Ghosh and Mallick / Ch 2 Pevsner) (5 Periods) Introduction. EMBL Nucleotide Sequence Database (EMBL-Bank): Introduction. Unit 4. Data Submission at DDBJ. Aim. Concept of Alignment. Scope and Research areas of Bioinformatics. Sequence Submission to NCBI. Molecular Phylogeny 39 | P a g e . Resources at DDBJ. Swiss-Prot: Introduction and Salient Features. Protein Information Resource (PIR): About PIR. Branches of Bioinformatics. Scoring Matrices. Protein Database. Sequence Retrieval. Databases in Bioinformatics Unit 3. Databases of PIR. Sequence Submission to EMBL. DNA Data Bank of Japan (DDBJ): Introduction. 5 Pevsner) (25 Periods) National Center for Biotechnology Information (NCBI): Tools and Databases of NCBI. Software for Phylogenetic Analyses. Sequence analysis tools.Paper 16-LSPT 409-BIOINFORMATICS THEORY Unit 1. Gene Expression Database. Biological Sequence Databases (Ch 4 Ghosh and Mallick / Ch 4. Data Retrieval in PIR. Introduction to Bioinformatics Marks: 100 (Ch 1 Ghosh and Mallick / Ch 1 Pevsner) (5 Periods) Introduction. Unit 2. Resources of PIR. MSA by CLUSTALW.

2. Ghosh Z. Construction of phylogenetic tree. Wiley-Blackwell. Sequence retrieval from databases. 3. Sequence alignment. and Bibekanand M. M. Benjamin Cummings. Marks: 50 40 | P a g e . J.. (2006) Discovering Genomics. (2008) Bioinformatics: Principles and Applications. Oxford University Press. Heyer L. (2009) Bioinformatics and Functional Genomics. II Edition. Microbial genome applications. Pevsner J. Crop improvement. 3. II Edition. SUGGESTED BOOKS 1. Sequence homology and Gene annotation. Nucleic acid and protein databases. Quantitative structure-activity relationship (QSAR) techniques in Drug Design.Unit 6. LSPP 409-BIOINFORMATICS PRACTICALS 1. 2. 5. Applications of Bioinformatics (Ch 11 Ghosh & Mallick / Ch 20 Pevsner) (7 Periods) Structural Bioinformatics in Drug Discovery. Campbell A. Proteomics and Bioinformatics. 4.

Vibrations of polyatomic molecules. rotational. Spectrochemical series. Wave-particle duality. Quantum Chemistry and Spectroscopy) THEORY Section A: Inorganic Chemistry-3 Marks: 100 (30 Lectures) Unit 1. Microwave (pure rotational) spectra of diatomic molecules. quantization. Structural information derived from vibrational spectra.Paper 17-CHPT 505. Difference between atomic and molecular spectra. Lanthanides and actinides: Electronic configurations. normalization of wavefunctions. Oxidation states. Particle in a 1-D box (complete solution). separation of lanthanides (ion-exchange method only). colour. Effect of hydrogen bonding (inter. concept of zero-point energy. Coordination Chemistry Valency Bond Theory (VBT): Inner and outer orbital complexes of Cr. Factors affecting the magnitude of ∆. Crystal field effects for weak and strong fields. Unit 3. Drawbacks of VBT. Born-Oppenheimer approximation: Separation of molecular energies into translational. Ni and Cu (coordination numbers 4 and 6). Square planar coordination. Section B: Physical Chemistry-4 (30 Lectures) Unit 4.Chemistry-5 (Chemistry of d-block elements. Crystal Field Theory Crystal field effect. Quantization of vibrational energy levels. Structural information derived from rotational spectroscopy. Transition Elements (3d series) General group trends with special reference to electronic configuration. Fe and Cu. Crystal field stabilization energy (CFSE). Tetragonal distortion of octahedral geometry. Electromagnetic radiation and its interaction with matter. Tetrahedral symmetry. Quantization of rotational energy levels. quantum mechanical operators. Quantum Chemistry & Spectroscopy Spectroscopy and its importance in chemistry. Structural and stereoisomerism in complexes with coordination numbers 4 and 6. Postulates of quantum mechanics. colour. Unit 2. Jahn-Teller distortion. Selection rules. lanthanide contraction. Rotational Motion: Schrödinger equation of a rigid rotator and brief discussion of its results (solution not required). Comparison of CFSE for Oh and Td complexes. Selection rules. Vibrational Motion: Schrödinger equation of a linear harmonic oscillator and brief discussion of its results (solution not required). magnetic and catalytic properties. variable valency. Fe. Free particle. Link between spectroscopy and quantum chemistry.and intramolecular) 41 | P a g e . IR spectra of diatomic molecules. Octahedra symmetry. Co. IUPAC system of Nomenclature. ability to form complexes and stability of various oxidation states (Latimer diagrams) for Mn. Types of spectroscopy. Group frequencies. magnetic properties. vibrational and electronic components.

F. Narosa (2004). Macmillan Publishing Co. 9. Photochemistry Laws of photochemistry. & Townsend.A. M. C. John Wiley. 5. Narosa (1998). 6. D. J. Estimation of total hardness of a given sample of water by complexometric titration. Estimation of the amount of nickel present in a given solution as Bis(dimethylglyoximato) nickel(II) or aluminium as oxinate in a given solution gravimetrically. Mahan. R. W. G. W.Petrucci. bathochromic and hypsochromic shifts. R. 42 | P a g e Marks: 50 . P. Estimation of (i) Mg2+ or (ii) Zn2+ by complexometric titrations using EDTA.: New York (1985). 2. CHPP 505. Electronic Spectroscopy: Electronic excited states. G. Quantum Chemistry and Spectroscopy) PRACTICALS Section A: Inorganic Chemistry 1. M.salicylic acid complex / Fe2+ .and substitution on vibrational frequencies. Physical Chemistry Tata McGraw-Hill (2007). Lambert-Beer’s law. Viva Books Pvt. Photoelectric cells. concentration) for various concentrations of a given coloured compound and estimate the concentration of the same in a given solution. Free Electron model and its application to electronic spectra of polyenes. auxochromes. Barrow. Fluorescence and phosphorescence. E.Chemistry-5 (Chemistry of d-block elements. SUGGESTED READINGS 1. 7. (1985) General Chemistry 5th Ed. Ltd. Photochemical and thermal reactions. 4. Determination of the composition of the Fe3+ . Lee :A New Concise Inorganic Chemistry. J. H.phenanthroline complex in solution by Job’s method.L.S. H. Gary Wulfsberg :Inorganic Chemistry. To draw calibration curve (absorbance at λmax vs. 8. Atkins : Inorganic Chemistry. chromophores. J. Physical Chemistry 4th Ed. 3. 3. F. General Chemistry Cengage Learning India Pvt. Cotton & G. 4. Wilkinson :Basic Inorganic Chemistry. B.: New Delhi (2009).B. Kotz. 2. Shriver and P. 5. Unit 5. Primary and secondary processes in photochemical reactions. Oxford University Press. Castellan. Treichel. Colour and constitution. University Chemistry 3rd Ed.. Quantum efficiency and reasons for high and low quantum yields. Ltd. D.

volumetrically or conductometrically b. (c) Conductometric titrations for the following systems (i) strong acid . lodide-persulphate reaction.6. Determination of concentration of Na+ and K+ using Flame Photometry. Acid hydrolysis of methyl acetate with hydrochloric acid. (a) Determination of the cell constant. (b) Study of the variation of molar conductivity of a strong electrolyte (KCl) and of a weak electrolyte (acetic acid) with concentration.strong base (III) Kinetic studies Study of the kinetics of the following reactions by integrated rate method: a. 43 | P a g e . Section B: Physical Chemistry (I) Potentiometric measurements (a) Strong acid with strong base (b) Weak acid with strong base (c) Mohr’s salt with potassium dichromate (II) Conductometric measurements.strong base (ii) weak acid .

Kuby) (7 Periods) Haematopoesis. 15. Innate. Lehninger) (5 Periods) Electron transport chain. 16. inhibition. Lehninger) (5 Periods) Unit 4.Paper 18-LSPT 510. Pentose phosphate pathway. Kuby)(5 Periods) Historical perspective of Immunology. Antigens: Properties of antigens. Lehninger) (10 Periods) Introduction. Immunoglobulins: (Chapter 4. Major Histocompatibility Complex: Structure and functions (Chapter 7. Kuby)(2 Periods) Endogenous pathway and exogenous pathway of antigen presentation Unit 12.BIOCHEMISTRY AND IMMUNOLOGY THEORY Marks: 100 Unit 1. mechanism of action. Cells and Organs of the Immune System: (Chapter 2. Cells of the immune system. Gluconeogenesis. Lehninger) (8 Periods) Glycolysis. Oxidative Phosphorylation: (Chapter 13. Polyclonal sera. kinetics. Kuby)(3 Periods) Unit 9. classes and function. Kuby)(3Periods) Basic structure. Active: Artificial and Natural Immunity Unit 7. Antigen Processing and Presentation: (Chapter 1. (Chapter 17. Carbohydrate Metabolism: (Chapter 14. Kuby)(6 Periods) Brief introduction to Vaccines. Citric acid cycle. Enzymes: (Chapter 6. Lehninger) (4 Periods) (Chapter 18.Passive: Artificial and Natural Immunity. Glycogen metabolism Unit 2. Overview of Immune System: (Chapter 1. allosteric enzymes and regulation Unit 5. Organs of the Immune system: Primary and Secondary lymphoid organs. Immune System in Health and Disease: (Chapter 19. Deamination and Urea cycle. Immunodeficiency and autoimmunity 44 | P a g e . Protein Metabolism: Transamination. Kuby)(2 Periods) Unit 11. Early theories of Immunology. Lymphatic system Unit 8. Lipid Metabolism: Biosynthesis and β-oxidation of palmatic acid Unit 3. Adaptive (cell mediated and humoral) . Oxidative phosphorylation and ATP synthase Unit 6. Monoclonal antibodies Unit 10. Adjuvants and Haptens (Chapter 3.

BIOCHEMISTRY AND IMMUNOLOGY PRACTICALS 1. P. S. Marks: 50 Color reaction to identify functional group in the given solution of carbohydrate. A.H Freeman and Co. 5.. Harper’s Illustrated Biochemistry. Kuby. (2009). IV Edition. Ouchterlony’s double immunodiffusion method. Delves. D. Cox. Freeman and Company. 6. Martin. R. 4. K. Nelson. Blackwell Publishing LSPP 510. Murray.. Roitt.. 3. (2006). Kindt. Color reaction to identify functional group in the given solution of proteins. 8. 45 | P a g e .. A. Viability and cell counting of peritoneal macrophages using trypan blue. J. Roitt's Essential Immunology. ABO blood group determination. and Lehninger. Granner.H. 2. (2006). R. Study the activity of Trypsin using fresh tissue extracts. L. Principles of Biochemistry. 2. I.. VI Edition. J.. W.. M. Lange Medical Books/McGraw-Hill. (2009). D. 7. XI edition. R. Study of the action of salivary amylase at optimum condition.. Mayes. Dissection and display of lymphoid organs. Immunology. P. M. A. A. and Rodwell.M. W.SUGGESTED BOOKS 1. B.L. 3. D. J. XXVIII Edition. Burton. Goldsby. Osborne. W. 4. J.. K. T. V.

micro and macronutrients. Structural organization of flower: Initiation and differentiation of floral organs. (Ch 3. microsporogenesis.10 Hopkins & Huner) (10 Periods) Unit 9. role of phytochrome and cryptochrome. Plant water relationship: Significance of water. water absorption and transport. (Ch-22 Raven P. mechanism of opening and closing of stomata.21 Hopkins & Huner) (11 Periods) Unit 8. Brassinosteroids and Jasmonates. ABA. significance of polarity. Role of physical factors in growth of plants: response to light photomorphogenesis. structure and types of ovule.26 Hopkins & Huner) (8 Periods) Unit 7.H. Fertilization: Pollination.3.20. 2nd Edition) (10 Periods) Unit 3. 7. pigments. types of embryo sacs (Bhojwani & Bhatnagar Chapter-1. ion uptake and role of mycorrhiza. response to temperature – vernalization. (Ch 7. Solute transport: Transport of inorganic and organic components. (Ch 18. 2nd Edition) (4 Periods) Unit 4. double fertilization. ethylene.8. structure and development of anther.25. PSI & PSII e-transport. biological clock.5.19. Developmental Biology: Introduction and scope. et al. transport pathwaysxylem and phloem. soil factors affecting their availability. 2.) (2 Periods) Unit 2. pollen-pistil interaction. (Ch 7. physiological basis of deficiency. (Bhojwani & Bhatnagar Chapter-6. 9 Hopkins & Huner) (4 Periods) 46 | P a g e . Role of growth regulators:auxin.24. transpiration. ATP synthesis C3 C4 & CAM Photorespiration. symptoms.Paper 19-LSPT 511.DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY-PLANT THEORY Marks: 100 Unit 1. photoperiodism. Mineral nutrition: essential elements.4. (Ch 2 Hopkins & Huner) (5 Periods) Unit 5. 4 Hopkins & Huner) (6 Periods) Unit 6.9. cytokinins. megasporogenesis. Photosynthesis: brief history. gibberellins. water potential. (Ch 3. signal transduction (overview). mechanism of light absorption and energy transfer.

To demonstrate effect of auxin on rooting/abscission/apical dominance.. Delaying of leaf senescence by application of cytokinn. Raghavan V (2000) Developmental Biology of Flowering Plants.F. Harcourt Academic Press.E. Determination of a effect of an environmental factor on the rate of transpiration by an excised twig using photometer. Introduction to Plant Physiology. W. (2005). 4th edn. House Pvt.. Study the Avena coleoptile curvature test. 9. To study the effect of ethrel application on fruit ripening.H. Dickinson WC (2000) Integrative Plant Anataomy. & Bhatnagar. 11. 47 | P a g e . Demonstrate Hill’s reaction using crude extract of leaves. Demonstrate the activity of nitrate reductase in leaf discs. 3. Freeman Company Publishers. 4..P. New Delhi 5. Bhojwani. USA 3. Study of monoscopic (Polygonium) type of embryo sac development (permanent slides/photographs). Study of embryo sac through electron micrographs showing egg apparatus. Raven P. LSPP 511. To study the dynamics of growth. (1999). 7. 10. Hopkins WG & Huner PA (2009) 4th edn. microsporogenesis. Study the effect of CO2 concentration on the rate of photosynthesis. 7th edn. Determination of stomatal index of leaf of the given plant material. Evert R. S. Determination of stomatal frequency of the leaf of given plant material. Vikas Pub. Study the effect of light intensity on the rate of photosynthesis. New York 4. S.H. John Wiley and Sons 2. 8. mature anther (permanent slides). Ltd. Structure of young anther wall.DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY-PLANT PRACTICALS Marks: 50 1. 5. 6. List of suggested experiment that should be demonstrated in the class and these may be kept for comments in the practical examination 1. 4. 5. Springer-Verlag. 2. 3. To demonstrate bolting in any rosette plant. 2.SUGGESTED BOOKS 1. USA. Embryology of Angiosperms. and Eichhorn S. Biology of Plants.S.

incomplete dominance. Kappa particles in Paramecium. 9:4:3. Linkage and Crossing over: (Ch 7 Pierce / Ch 5 Klug and Cummings / Ch 7 Gardner) (8 Periods) • • Linkage: concept & history.Paper 20-LSPT 512. 5. Chromosomal Aberrations: 48 | P a g e . Multiple allelism Pleiotropism Chromosome theory of Inheritance. 6 Pierce. Crossing over: concept and significance. 12:3:1. Sex-determination and Sex-linked Inheritance: Cummings / Ch 4 Gardner) • • Sex determination in Human. leaf variegation in Mirabilis jalapa. (Ch 4 Pierce / Ch 7 Klug and (8 Periods) Unit 2. Chi Square Pedigree Analysis Cytoplasmic Inheritance: Shell Coiling in Snail. recombination frequency. 9:7. Mutations: • • Types of mutations.GENETICS AND GENOMICS THEORY Marks: 100 Unit 1. 13 Russell / Ch 20 Gardner) (16 Periods) • • • • • • • • • • Brief life history of Mendel Terminologies Laws of Inheritance Modified Mandelian Ratios: 2:1. Ch 16 Klug and Cummings / Ch 11 Gardner) (6 Periods) Unit 4. Male sterility. linkage maps based on two factor crosses. effects of physical & chemical mutagens CLB method of detection of mutations (Ch 9 Pierce / Ch 8 Klug and Cummings / Ch 17 Russell) (14 Periods) Unit 5. 12. Drosophila & plants Sex linked inheritance Unit 3. Ch 3. 1:2:1. 4 Klug and Cummings / Ch 11. (Ch 10 Pierce. complete & incomplete linkage.dominance.Co. cytological proof of crossing over. 13:3. bridges experiment. Heredity: (Ch 3.lethal Genes. coupling & repulsion.

2. Snustad. Colour blindness.Ishihara’s Chart 7. Polyploidy and Aneuploidy • Structural chromosomal changes: Deletions. Construction of linkage map based on recombination frequency data obtained from a twopoint cross (use real life data). Human Genetic Syndromes (Down’s. Chi square analysis of a dihybrid F2 population data 4. Inversions & Translocations. B. Inversion bridge.. Proteomics. NY LSPP 512. W. W. 9:4:3. Pedigree analysis of hemophilia in Queen Victoria family 6. Meiosis – Allium cepa Buds 5. Freeman& co. III Edition. Cummings. M. J. Synteny. metabolomics. Unit 6. 4. (2008). Klug. Barr Bodies. C. Benjamin Cummings. A. Drosophila melanogaster. 13:3. Genomics: (Ch 20 Pierce / Ch 10 Russell) (8 Periods) Introductions to OMICS: Genomics. Mice and Humans. (2009).GENETICS AND GENOMICS PRACTICALS Marks: 50 1. 49 | P a g e . 3.J. Functional Genomics Comparative Genomics: Homologs. Laggards.A. Study of the following with the help of photographs: Sex chromosomes in Melandrium/ Coccinia. 12:3:1 2. Concepts of Genetics. M. Paralogs & orthologs.A Molecular Approach.. Translocation Ring (Rhoeo).• Numerical chromosomal changes: Euploidy. Spencer. Gene Interactions with the help of Drosophila culture for the following dihybrid F2 segregation ratios: 9:7. Multivalents. Human Genome project. E. P. Genetics. (2008).. Comparative genomics of Chimpanzees and human. glycomics • • • • Structural Genomics: Sequencing Strategies. Klinefelter’s). XI Edition. Gardner. Simmons. transcriptomics. Russell. Model organisms: Escherichia coli.S.P. 3. iGenetics.A Conceptual Approach. Duplications. Wiley India.J. Pierce.R. Arabidopsis thaliana SUGGESTED BOOKS 1. D.. Benjamin Cummings. H. Turner’s. VIII editon Principles of Genetics. (2009).

[Co(NH3)6]Cl3 . Secondary.A study of the following compounds (including preparation and important properties). Amino Acids. Structures of methyl lithium. Polynuclear and Heteronuclear aromatic compounds: Properties of the following compounds with reference to electrophilic and nucleophilic substitution: Naphthalene. Zeiss salt and ferrocene. K4[Fe(CN)6]. Bio-Inorganic Chemistry A brief introduction to bio-inorganic chemistry. Role of Mg2+ ions in energy production and chlorophyll. Preparation. Synergic effects (VB approach). Role of Ca2+ in blood clotting. Furan.π and multicentre bonds). K2Cr2O7.Chemistry-6 (Organometallics. complexation with Cu2+ ions. sodium nitroprusside. Overview of Primary. Peroxo compounds of Cr. σ . Proteins and UV-IR Spectroscopy) THEORY Section A: Inorganic Chemistry-4 Marks: 100 (30 Lectures) Unit 1. Unit 2. Zwitter ion. stabilization of protein structures and structural role (bones). Reactions of Amino acids: ester of –COOH group. KMnO4. Peptides and Proteins: Preparation of Amino Acids: Strecker synthesis. EAN rule as applied to carbonyls. Bio-inorganic Chemistry. acetylation of –NH2 group. Section B: Organic Chemistry-4 (30 Lectures) Unit 1. Chemistry of 3d metals Oxidation states displayed by Cr. (MO diagram of CO can be referred to for synergic effect to IR frequencies).acceptorbehaviour of carbon monoxide. Role of metal ions present in biological systems with special reference to Na+. Organometallic Compounds Definition and Classification with appropriate examples based on nature of metal-carbon bond (ionic. Unit 2. Ni and Co. Unit 3. Isoelectric point and Electrophoresis. Synthesis of simple peptides (upto dipeptides) 50 | P a g e . and Pyridine. Fe. Anthracene . Thiophene. ninhydrin test. Na3[Co(NO2)6]. K+ and Mg2+ ions: Na/K pump. Determination of Primary structure of Peptides by degradation Edmann degradation (N-terminal) and C–terminal (thiohydantoin and with carboxypeptidase enzyme). π . Tertiary and Quaternary Structure of proteins.Paper 21-CHPT 606. structure. using Gabriel’s phthalimide synthesis. bonding and properties of mononuclear and polynuclear carbonyls of 3d metals. Co. Pyrrole.

Bio-inorganic Chemistry. Miessler and Donald A. chromophore. Lee :A New Concise Inorganic Chemistry. 9.B.by N-protection (t-butyloxycarbonyl and phthaloyl) & C-activating groups and Merrifield solidphase synthesis. I & II). auxochrome.L.S. IR spectra of alkanes. Orient Longman. 10.L. Morrison & R. E.A. Morrill: Spectroscopic Identification of Organic Compounds. aldehydes . functional group and Finger print region.β – unsaturated compounds. Prentice Hall. 5. Cotton & G.T. R. S. Pearson Publication. E. Unit 3. A13+ and Cr3+ or 51 | P a g e Marks: 50 .S. carboxylic acids and derivatives (effect of substitution on >C=O stretching absorptions). bathochromic and hypsochromic shifts. Pearson Publication. James E. Bassler and T.B. 2. SUGGESTED READINGS 1. Chand CHPP 606. John R. R. Application of electronic spectroscopy and Woodward rules for calculating λ max of conjugated dienes and α. F.M. J.C. L. ketones. Infrared radiations and types of molecular vibrations. 8. Silverstein. λmax & ε max. Arun Bahl and B. Huheey. Boyd: Organic Chemistry. Peter Sykes: A Guide Book to Mechanism in Organic Chemistry. Wilkinson: Basic Inorganic Chemistry. Application of Spectroscopy to Simple Organic Molecules Application of visible.D. Bahl : Advanced Organic Chemistry.Chemistry-6 (Organometallics. electronic transitions . Prentice Hall. Finar: Organic Chemistry (Vol. Proteins and UV-IR Spectroscopy) PRACTICALS Section A: Inorganic Chemistry 1. John Wiley & Sons. alkenes and simple alcohols (inter and intra molecular Hydrogen bonding). Separation of mixtures by chromatography: Measure the Rf value in each case. 7. ultraviolet and Infrared spectroscopy in organic molecules. 4. Electromagnetic radiations. (Combination of two ions to be given) Paper chromatographic separation of Fe3+.L. G.C. Dyer: Applications of Absorption Spectroscopy of OrganicCompounds. John Wiley & Sons. S. I. Ellen Keiter and Richard Keiter: Inorganic Chemistry: Principles of Structure and Reactivity. G. Tarr: Inorganic Chemistry. 6.N. 3.

ketonic. Co2+. Mn2+ and Zn2+ 2. amide. 52 | P a g e . NaCl. MgCl2 and Section B: Organic Chemistry Systematic Qualitative Organic Analysis of Organic Compounds possessing monofunctional groups (-COOH. Preparation of any two of the following complexes and measurement of their conductivity: (i) tetraamminecarbonatocobalt (III) nitrate (ii) tetraamminecopper (II) sulphate (iii) potassium trioxalatoferrate (III) trihydrate Compare the conductance of the complexes with that of M/1000 solution of LiCl3. nitro. aldehydic.Paper chromatographic separation of Ni2+. phenolic. 1o amines) and preparation of one derivative.

Gene therapy (ADA and Cystic fibrosis) and Stem Cells.e. 12. Southern. 21. Filariasis. Unit 4. Ch 3. Agarose and Polyacrylamide Gel Electrophoresis. Molecular Techniques in Gene manipulation (Ch 1. Polymerase chain reaction and DNA microarrays. SCP). Recombinant DNA in medicines (Recombinant insulin and Human growth hormone). plants and animals).Paper 22-LSPT 613. Construction and screening of DNA libraries. 19. Transformation techniques (microbial. 11. Malaria. Northern and Western blotting). food preservation. Dengue. transmission. organic acids.APPLIED BIOLOGY AND BIOTECHNOLOGY THEORY Unit 1. DNA sequencing (MaxamGilbert and Sanger methods). Ethics and regulation of GM organisms 53 | P a g e . amino acids. Applications of Biotechnology (Ch 9. 4 Glick & Pasternak) (16 Periods) Introduction to the concept of Recombinant DNA Technology. Amoebiasis. Human diseases Marks: 100 (Ch3. 20. Huntington’s disease and Sickle cell anemia). Micro-organism as food (e. Cloning vectors. Recombinant vaccines.g. 10. Japanese encephalitis Unit 2. Production and applications of transgenic plants (biotic. 29 Pelczar) (12Periods) Microbiology of fermented food and food-borne diseases. RNA and Proteins (i. Molecular analysis of DNA. Unit 3. 5 Park) (10 Periods) Epidemiology of infectious disease. abiotic and improvement of nutritional quality) and transgenic animals (generation of medicines and hormones). Food and industrial microbiology (Ch 28. Major products of industrial microbiology-antibiotics. prevention and control of human diseasesTuberculosis. Bioremediation. vitamins. pharmaceuticals. 23 Glick & Pasternak) (22 Periods) Molecular diagnosis of genetic diseases (Cystic fibrosis. Restriction and modifying enzymes.

Gene amplification using PCR 6. ASM press. Separation of proteins by SDS-PAGE. 3rd edition. R. J. J. Analysis of DNA fingerprint 8. Park. (2007) Recombinant DNA. helminth parasites and arthropod vectors associated with human diseases.A short course. J. Freeman and Co.APPLIED BIOLOGY AND BIOTECHNOLOGY PRACTICALS 1. (2010) Molecular Biotechnology. Witkowski. Glick. Restriction Endonuclease Digestion of plasmid DNA. Caudy.. K (2007) Preventive and social medicine B. LSPP 613. 4. 4. and Pasternak.M. 7. Myers.Principles and applications of recombinant DNA. 3. Ligation of Target DNA.J. M. 2.Genes and Genomes. New Delhi 2. 9. Washington.D.K. J. Transformation of E. Watson. NY. Study of protozoan. B. Marks: 50 54 | P a g e .R. Isolation of plasmid DNA from E. et al (2001) Microbiology 5th edition Tata McGraw-Hill Co. 5. A.SUGGESTED BOOKS 1. Pelczar. DNA sequencing: Interpretation of sequence from the data provided.coli (pUC 18/19) and calculation of transformation efficiency. coli.B publishers 3...

fertilization. cell fate Unit 3. B.ANIMAL THEORY Unit 1. Unit 5.Paper 23-LSPT 614. Endocrine system and reproduction (Ch 45. 55 | P a g e . Functional anatomy of kidney. 46 Campbell) (6 Periods) Common features of endocrine system. 2 Gilbert) (3 Neural tissue. Digestion & absorption of food Structure & function of gastrointestinal tract Unit 4. gastrulation. functional role of endocrine glands. Functioning of excitable tissue (nerve & muscle) Vander) (Ch 6 Sec A. Respiration & Renal physiology (Ch 13 Vander/ Ch 44 Campbell) (12 Periods) Transport of oxygen & carbon dioxide in blood. C. Ch 9 Sec A (12 Periods) (Ch 15 Vander) (6 Periods) (Ch 47 Campbell) (12 Periods) Marks: 100 (Ch 1.DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY. E Vander) (9 Periods) Heartbeat coordination. B. Animal development Gametogenesis. Unit 7. Anatomical aspects of development biology Unit 2. Cardiovascular physiology (Ch 12 Sec A. skeletal muscle –molecular mechanism of contraction. generation & propagation of nerve impulse. water balance & counter-current mechanism Unit 6. Principles of developmental biology Periods) History. Cardiovascular pattern in health & disease. cardiac cycle. cleavage.

thyroid. S. adrenal. Histological slides. Raff. Gilbert. 4. & Reece. 28h. neural tube). pancreas. neurula (neural fold.DEVELOPMENTAL BIOLOGY AND PHYSIOLOGY -ANIMAL PRACTICALS Marks: 50 1. Mc Graw Hill LSPP 614. (2006) 8th edn.Vander’s Human Physiology. Study of development stages of chick 18h. Widmaier E. H. Pearson Education. Preparation of haemin and hemochromogen crystals. trachea. ovary.cleavage types. (2004) 9th edn. and Dorling Kindersely Publishing.F. cartilage.. (2005) 8th edn. bone.Inc. Strang. Campbell N. duodenum. oesophagus. gastrula.SUGGESTED BOOKS 1. Biology. external gill stage of tadpole. rectum. 3. spleen. 6. 2. Inc.B. 24h. Sinauer Associates. lung. 48h. kidney. liver.T. pituitary. J. Study the reflex action in a spinal frog 5. 36h. 2.P. 72h by raising chick embryo in the laboratory. testis 56 | P a g e . salivary glands. 3. K. ileum. blastula.. Study of development stages of frog: .Examination of sections of mammalian skin.A. Inc. Recording of frog’s heart beat in situ. Developmental Biology.

predation-types. National and Local). global climatic change 57 | P a g e . density. mortality. 7 Miller) (6 Periods) Population attributes. Zoogeography: Zoogeographic realms. predator-prey system.Paper 24-LSPT 615. Hydrologic cycle. natality. Community characteristics. Biogeography (Part 23. Unit 2. 21. Bioresource management (Unit 4 Mishra/ Ch 6 Allaby/ Ch 4. Unit 5. (18 Periods) Inter-relationships between living world and environment. EIA-Environmental Impact Assessment (Global. 8. dispersal and dispersion of population. life history strategies. social parasitism. wildlife sanctuaries.organization and concept of habitats and niche. ecosystem and its components (abiotic and biotic). 25 Smith) (10 Periods) Phytogeography. environmental pollution. Threatened species of animals Unit 4. population interactions. Community and Ecosystem Ch 20. exponential and logistic growth. Environmental Issues. 9 Miller) (14 Periods) Biodiversity and regional conservation strategies success stories with reference to India and sustainable utilization. sex ratio. Population and Community Ecology (Part 4 and 5 Smith /Ch 6. endangered and threatened species of plants and animals in India. functional and numerical response. major plant communities of the world. parks and biosphere reserves in India. 24. 15. Introduction to Ecology. Phytogeographic realms. Vegetation of India. laws of limiting factors). 16 Miller) (10 Periods) Impact of urbanization and industrialization. 22 Smith/ Ch 3 Miller) Marks: 100 (Ch 4 Allaby. Environment related concepts and laws (theory of tolerance. germplasm banks. Biosphere. Principles of wildlife management. Bioenergetics. host-parasite interactions. bioremediation. Concept of habitat and niche. age ratio. biomes.ECOLOGY AND ENVIRONMENTAL MANAGEMENT THEORY Unit 1. Policies and Regulation (Unit 8 Mishra/ Ch 27. 29 Smith/ Ch 11. Biogeochemical cycles. symbiosis Unit 3. restoration of degraded ecosystems.

Measurement of soil pH. R. Study of the biotic and abiotic components of any one ecosystem 2. (2002) Basics of Environmental Science Routledge 3. (2006) Elements of Ecology Ist editon Pearson Publications 4.C. Study of population density by using different methods – natural and hypothetical community 3. Mishra. Project work . soil analysis by rapid field method 5. Miller. M.SUGGESTED BOOKS 1.sieve method.ECOLOGY AND ENVIRONMENTAL MANAGEMENT PRACTICALS 1.T (2006) Environmental Science 11th edition Brooks/Cole LSPP 615. (2005) Environmental Studies Selective and Scientific Books. temperature and texture. Study of life tables and Survivorship curves 4. Smith. A.water or air pollution Conventional sources of energy Visit to a National Park or wild life sanctuary One Ecosystem – Natural or Human modified Marks: 50 58 | P a g e . T. G. Allaby. Ecological adaptations of two animals and two plants 6. New Delhi 2. and Smith.M.any one • • • • • Restoration of biodiversity Collection of data on.

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