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DRUG STUDY Name of drug Generic Name Vitamin B complex Brand Name Classification Indication / contraindication Indication Pernicious

Anemia Contraindication Hypersensitivity to vitamin B12 or cobalt. early Leber’s disease Mode of Action Adverse effect/ side effects CV: Peripheral vascular thrombosis, heart failure. GI:transient Diarrhea. Respiratory: pulmonary Edema. Skin: itching, Transitory exanthema, urticaria. Other: anaphylaxis, anaphylactoid reactions with parenteral administration , pain or burning at injection site Nursing responsibilities BEFORE: ~ Determine reticulocyte count, hct, Vit.B12, iron, folate levels before beginning therapy. ~ Obtain a sensitivity test history before administration ~ Avoid I.V. administration bec. faster systemic elimination will reduce effectiveness of vitamin. DURING: ~ Don’t give large doses ofvitaminB12 routinely; drugis lost through excretion.

Vitamins and Minerals

A coenzyme that stimulate metabolic function and is needed for cell replication, hematopoiesis, and nucleoprotein and myelin synthesis

as anemia correct itself. as needed .~ Don’t mix parenteral preparation in same syringe with other drugs. ~ Monitor patient for hypokalemia for first 48 hours. Give potassium supplements. AFTER: ~ Protect Vit.B12 from light. Don’t refrigerate or freeze.

Proteusmirabilis. glossitis Hematologic: Thrombocytopenia. including Staphylococcus saprophyticus Treatment of acute otitis media due to susceptible strains of S.neutropenia. influenza in children Contraindications Allergy to trimethoprim. pneumonia and H.leukopenia . pruritus.megaloblastica nemia. nausea vomiting.methemoglobinemia.Name of drug Classificatio n Antibacterial Indication / contraindication Indications Uncomplicated UTIs caused by susceptible strains of E. coli. Entero-bacter species.e levated serumtransaminase andbilirubin.pregnancy (teratogenic inpreclinical studies). Bactrim and Sulfatrim .megaloblastic anemiadue to folate deficiency.combination blocks twoconsecutive steps in bacterialsynthesi s of essential nucleicacids. Mode of Action Blocks synthesisof tetr ahydrofolicaci d. protein Adverse effect/ side effects Dermatologic: Rash.exfoliative dermatitis GI: Epigastric distress. Klebsiella pneumoniae. increasedBUN and serumcreatinine levels Other: Fever Nursing responsibilities Assess allergic reactions Monitor I and O ratio Monitor kidney function Assess type of infection: obtain C&S before starting therapy Generic Name: Cotrimoxazole (200mg/5ml)5ml BID Brand Name: Septra. and coagulasenegative Staphylococcus species.

Instruct patient torepot cravings to physician immediately. or any componen t of theformulation. Adverse effect/ side effects Dizziness Nausea Drowsiness Dry mouth Constipation Headache Sweating Vomiting Itching Rash Visualdisturbances Vertigo Nursing responsibilities Tell patient thatdriving or operatingmachine ry should beavoided until the effectof drug wears off. centrallyacting analgesics.Name of drug Generic Name: Tramadol Brand Name: Ultram Classification Indication / contraindication Indications Moderate to moderately severe pain Contraindications Hypersensitivity totramadol. Mode of Action Decreased pain. or psychotropic drugs. Inhibits reuptake of serotonin and norepinephrine in the CNS. opioids.hypnotic s. partic ularly whencombined with other CNS depressants Analgesic opiate . opioiddependent patients.opioid s. Inform client that medication may c auseCNS depression and/or respiratory depression.acute intoxicationwith alcohol. Pharmacologi c Mechanism Binds to muopioid receptors.

pregnancy \u2022 Physical: Skin color. pregnancy. R. chest tightness Nursing responsibilities Sedative History: Allergy to hydroxyzine or cetirizine. lactation. orientation. dyspnea. lesions. affect. adjunct in organic disease states in which anxiety is manifested. reflexes. uncomplicated vomiting in children.Name of drug Generic Name: hydroxyzine hydrochlori de Brand Name: hydroxyzine Classification Indication / contraindication Indications Symptomatic relief of anxiety and tension associated with psychoneurosis. antiemetic and analgesic properties. lactation. texture. Adverse effect/ side effects CNS:Drowsiness. alcoholism and asthma. bronchodilator. \u2022 Use cautiously with uncomplicated vomiting in children (may contribute to Reye's syndrome or unfavorably Mode of Action Competitively blocks the effects of histamine at peripheral H1 receptor sites. has skeletal muscle relaxing. adventitious sounds . prior to dental procedures Contraindications Contraindicated with allergy to hydroxyzine. involunta ry motor activity. including tremor and seizures \u2022 GI: Dry mouth \u2022 Hypersensitivity: Wheezing .

pain. older adults often self-limit liquids. Nursing responsibilities Laxative Contraindication Assessment & Drug Effects In children if the initial dose causes diarrhea. Adverse effect/ side effects Flatulence. borborygmi. vomiting. hypernatremia. belching. appears to involve metabolism of lactose to organic acids by resident intestinal bacteria. abdominal cramps . and distention (initial dose).influence its outcome. extrapyramidal effects may obscure diagnosis of Reye's syndrome) Name of drug Generic Name: Lactulose Brand Name: Cephulac Chronulac Movelax Lilac Classification Indication / contraindication Indications relief of chronic constipation Mode of Action Reduces blood ammonia.diarrhea (excessive dose). colon accumulation of hydrogen gas. Lactuloseinduced osmotic changes in the bowel support intestinal water loss and potential . Discontinue if diarrhea persists. Promote fluid intake (>=1500–2000 mL/d) during drug therapy for constipation. dosage is reduced immediately. nausea.

about 24–48 h is needed. Do not self-medicate with another laxative due to slow onset of drug action.. Discuss strategy with physician. therefore. Notify physician if diarrhea (i. .e. more than 2 or 3 soft stools/d) persists more than 24–48 h. Diarrhea is a sign of overdosage. Patient & Family Education Laxative action is not instituted until drug reaches the colon. Do not breast feed while taking this drug without consulting physician. Dose adjustment may be indicated.hypernatremia.