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Name of drug Clopidogrel

Specific action Anti-platelet Agent

Mechanism of action

Indication Used in thromboembolic disorders. it is an analogue of ticlopidine and acts by inhibiting adenosine diphosphate platelet aggregation.

Contraindication Side effects Hypersensitivity, active pathological bleeding such as peptic ulcer or intracranial hemorrhage.          GI bleeding intracranial bleeding neutropenia agranulocytosis abdominal pain dyspepsia gastritis constipation diarrhea

Blocks ADP receptors, which prevent fibrinogen binding at that site and thereby reduce the possibility of platelet adhesion and aggregation.

Nursing Responsibilities  assess for any hypersensitivity reactions  Assess for any bleeding or any side effects  Monitor lab. result  monitor client’s general condition

Name of drug ASA

Specific action Anti-platelet agent

Mechanism of action

Indication Prevention of myocardial infarction and stroke. analgesic and anti-pyretic

Contraindication Side effects     Patients with dyspepsia hemophilia hemorrhagic disorder gout
 GI disturbances

Nursing Responsibilities

Relieves pain and reduces inflammation by inhibition of peripheral prostaglandin synthesis. it also inhibits the synthesis or action of other mediators of inflammation.

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 allergic reaction hypoprothrombinemia reye’s syndrome    

Assess for any bleeding disorder assess for any allergic reaction take with meals monitor vital signs Monitor lab. result

Contraindication Side effects Conditions with a high risk of uncontrollable hemorrhage including major bleeding disorders and focal lesions. Patients with high risk of thromboembolism. severe infections and rheumatic disease. Prophylaxis of venous thromboembolism in medical patients bedridden due to acute illnesses including cardiac insufficiency.Name of drug Enoxaparin Specific action Anti-coagulant Mechanism of action Indication Prophylaxis of venous thrombosis in surgical patients.thrombin complex and deactivates thrombin. respiratory failure. Nursing Responsibilities  Assess for any bleeding disorder before administration  assess for any bleeding  assess for complaints of pain or any side effects  monitor vital signs  monitor client’s general condition .      hemorrhage thrombocytopenia pain hematoma mild irritation Accelerates formation of antithrombin IIIB. preventing conversion of fibrinogen to fibrin.

   monitor for any side effects monitor client’s level of consciousness monitor vital signs . antipyretic and muscle relaxant Mechanism of action Indication Relief of moderate to severe pain Contraindication Side effects  Known hypersensitivity Binds with opioid receptors in the CNS causing alteration of both perception of and emotional response to pain through unknown mechanism.     respiratory depression acute or severe bronchial asthma paralytic ileus pregnancy and lactation          chills pruritus sweating abdominal pains anorexia constipation dry mouth dyspepsia nausea and vomiting Nursing Responsibilities  assess hypersensitivity reaction  Assess for any contraindicatio n before administration of meds.Name of drug Morphine sulfate Specific action Analgesic.

cirrhosis of the liver.Name of drug Furosemide Specific action Loop diuretics Mechanism of action Indication Treatment of edema associated with CHF. and renal disease including nephritic syndrome. Contraindication Side effects      anuria hepatic coma severe hypokalemia hyponatremia hypovolemia      Nursing Responsibilities Inhibits sodium and chloride reabsorption at the proximal tubules. Symptomatic  hypotension dehydration hemoconcentration  hypokalemia  hyponatrmia   Assess and monitor lab. useful as an adjunct to hypotensive agents in the treatment of acute pulmonary edema. chloride and potassium. distal tubules and ascending loop of henle leading to excretion of water together with sodium. results monitor vital signs monitor intake and output encourage to eat foods rich in potassium like bananas monitor and regulate IVF properly .

peripheral vessel disease. Patients at high risk of coronary heart disease including patients with diabetes. result . or witrh existing coronary heart disease to reduce risk of CV death Contraindication     hypersensitivity active liver disease children pregnancy and lactation Side effects         abdominal pain constipation flatulence nausea acid vomiting diarrhea dyspepsia headache Nursing Responsibilities Inhibits HMGCOA reductase enzyme.Name of drug Simvastatin Specific action Anti-lipidemic Mechanism of action Indication Adjunct to diet for treatment of hypercholesterolemia. this enzyme is needed for cholesterol production. take with meals avoid foods high in fats monitor vital signs Monitor lab. history of stroke or other cerebrovascular disease. which reduces cholesterol synthesis.       Assess for any hypersensitivi ty reaction Assess for any contraindicati on before administratio n of meds.

reduces ion concentration of K. magnesium and phosphate      assess lab result assess for hypercalcemia avoid foods rich in calcium monitor vital signs monitor client’s general condition . Contraindication Side effects   hypercalcemia disturbed amino acid metabolism  hypercalcemia Nursing Responsibilities Normalizes metabolic process. promotes recycling product exchange.Name of drug Ketosteril Specific action ketoanalogues Mechanism of action Indication Prevention and therapy of damages that is faulty or deficient protein metabolism in chronic renal insufficiency in connection with limited protein in food of 40g/day patient with 5 and 15 ml/min.

Reduction of fever. temp. angioedema or nasal polyps are precipitated by other NSAIDs advance kidney and liver disease      fluid retention increased BP hypotension CVA palpitation Decreases fever by inhibiting the effects of pyrogens on the hypothalamic heat regulating centers and by a hypothalamic action leading to sweating and vasodilation . Contraindication Side effects  patients in whom bronchospasm . and BP Monitor lab.Name of drug Paracetamol Specific action NSAIDs Mechanism of action Indication Faster relief of mild to moderately severe pain of musculoskeletal origin . Relieves pain by inhibiting prostaglandin synthesis at the CNS but does not have antiinflammatory action because of its minimal effect on peripheral prostaglandin synthesis.     Monitor vital signs esp. Nursing Responsibilities  Assess general condition of the patient  Assess for any contraindicatio n before administration of meds. result monitor intake and output .