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DRUG STUDY

NAME OF DRUG Brand Name: Topamax Generic Name: Topiramate Dosage: Tablet 100mg Classification: anticonvulsant (antiepilepsy) drug THERAPEUTIC EFFECTS Unknown. May block a sodium channel, potentiate the activity of gammaaminobutyrate, and antagonize the ability of kainate to activate an excitatory amino acid (glutamate) receptor. INDICATIONS CONTRAINDICATIONS ADVERSE EFFECT NURSING CONSIDERATIONS If needed, withdraw antiepileptics (including topiramate) gradually to minimize risk of increased seizure activity. Monitoring topiramate level isn’t necessary. Oligohidrosis and hyperthermia have have been infrequently reported, mainly in pediatric patients taking topiramate. Monitor patient closely, especially in hot weather. Drug is rapidly cleared by dialysis may result in low

Adjunct treatment for primary generalized tonic-clonic seizures.

Contraindicated in patients hypersensitive to drug or its components.

CNS: fever, abnormal coordination, aggressive reaction, agitation, apathy, confusion, depression, generalized tonic-clonic seizures, suicide attempts, insomnia, mood problems, fatigue, vertigo, malaise, difficulty with concentration. CV: chest pains, palpitations, vasodilation, edema. EENT: abnormal vision, conjunctivitis, diplopia, eye pain, epistaxis, hearing problems, tinnitus, pharyngitis, sinusitis, nystagmus. GI: abdominal pain, anorexia, constipation, diarrhea, dry mouth, dyspepsia, flatulence, gastroenteritis, gingivitis, nausea, vomiting, taste perversion.

flulike syndrome. Musculoskeletal: arthralgia. muscle weakness. coughing. characterized by acute myopia and secondary angle closure glaucoma. rigors. hematuria. pruritus. hot flashes. lymphadenopathy. drug levels and seizures. impotence. rash. urinary frequency. breast pain. . Other: Decreased libido. dyspnea. Hematologic: anemia. A supplemental dose may be needed. back or leg pain.GU: amenorrhea. leucorrhea. dysmenorrheal. body odor. UTI. menorrhagia. menstrual disorder. Respiratory: Bronchitis. leucopenia. increased sweating. myalgia. urinary incontinence. Alert: don’t confuse Topmax with Toprol-XL. Stop drug if an ocular adverse event occurs. renal calculi. intermenstrual bleeding. dysuria. vaginitis. Metabolic: increased or decreased weight.

thirst. urinary tract infection. and hepatic impairment . Obtain baseline and periodic liver function test results. takes anticholinergics . ecchymosis. GU: hematuria. akathisia. suicide attempt. which is rare Long term treatment of schizophrenia. insomnia. amenorrhea. May block dopamine and 5-HT2 receptors. tardive dyskinesia. urinary incontinence. abnormal gait. CV: orthostatic hypotension. dizziness.DRUG STUDY NAME OF DRUG Brand Name: Zyprexa Generic Name: Olanzapine 10mg THERAPEUTIC EFFECTS Unknown. increased salivation. metrorrhagia. conjunctivitis. articulation impairment. history of seizures or conditions that might lower the seizure threshold. INDICATIONS CONTRAINDICATIONS ADVERSE EFFECT NURSING CONSIDERATIONS Monitor patient for abnormal body temperature regulation. Contraindicated in patients hypersensitive to drugs. dyspepsia. is exposed to extreme heat.Also use cautiously in in elderly patients. peripheral edema. especially if he excercises. tachycardia. personality disorder. Alert: watch for evidence of neuroleptic malignant syndrome (hyperpyrexia. CNS: somnolence. . asthenia. Use cautiously in patients with heart disease. hypertension. tremor. fever. dry mouth. those with a history of paralytic ileus. autonomic instability). muscle rigidity. vomiting. EENT: amblyopia. and those at risk for aspiration pneumonia. Monitor patient for weight gain. or is dehydrated. neurolyptic malignant syndrome. altered mental status. parkinsonism. conditions that predispose patient to hypotension. pharyngitis. GI: constipation. rhinitis. vaginitis. or angle-closure glaucoma. cerebrovascular disease. increased appetite. chest pain. prostatic hyperplasia.

Stop drug immediately. Monitor patient for tardive dyskinesia. but commonly fatal. back pain. It may not appear unil months or years later and may disappear spontaneously for life despite stopping drug. hypertonia. injury. twitching. Alert: don’t confuse olanzapine with olsalazine or Zyprexa with Zyrtec.Hematologic: leucopenia Metabolic: weight gain Musculoskeletal: joint pain. monitor and treat patient as needed. extremity pain. dyspnea Skin: sweating Other: flulike syndrome. neck rigidity. Respiratory: increased cough. which may occur after prolonged use. .

ear pain. orthostatic hypotension. tachycardia.DRUG STUDY NAME OF DRUG Brand Name: Abilify 15mg THERAPEUTIC EFFECTS INDICATIONS CONTRAINDICATIONS ADVERSE EFFECT CNS: headache. increased salivation. blurred vision. insomnia. chest pain hypertension. NURSING CONSIDERATIONS Alert: neuroleptic malignant syndrome may occur with aripiprazole use. anxiety. sucha s those with alzheimer’s disease. autism. bradycardia. abdominal pain. anorexia. vomiting. Give prescriptions only for small quantities of tablets. Use cautiously in patients at risk for aspiration pneumonia. Contraindicated in patients hypersensitive to aripiprazole. Use cautiously in patients with CV disease. EENT: rhihitis. to Thought to exhibit its antipsychotic effects through partial agonist Generic activity at D2 Name: and serotonin Aripiprazole 1A receptors and antagonist activity at serotonin 2A receptors. Monitor patient for signs and symptoms of dyskinesia. Hematologic: ecchymosis. esophageal dysmotility. GU: urinary incontinence. diarrhea. A prescription drug often used for the treatment of bipolar disorder. . Treat patient with the smallest dose for the shortest time and periodically reevaluated for continued treatment. GI: nausea. conjuncyivitis. schizophrenia. CV: peripheral edema. and depression (when used along with antidepressants). constipation. light headedness.

weight loss. cough. Reference: Nursing2009 Drug Handbook by Lippincott Williams & Wilkins . pneumonia. Other: flulike syndrome. Metabolic: weight gain. Musculoskeletal: neck pain. ulcer. dry skin.anemia. reduce risk of overdose. neck stiffness. Skin: rash. muscle cramps. Respiratory: dyspnea. sweating. pruritus.