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Continuous Intra-arterial Blood Glucose Monitor (CAGM)

Problem:
Because the bodies of the people with diabetes are unable to properly
regulate blood glucose levels, the people must compensate for their bodies by
regulating it themselves. A diabetic must undergo the painful hassle of pricking
their fingers in order to read their blood glucose levels. Current continuous blood
glucose monitors (CGM) are problematic because they take readings from the
interstitial fluid, which then causes a lag in the readings because it is not taken
directly from the blood. In addition, the CGM must be calibrated every so often,
which again requires lancing and an external blood glucose monitor.

Solution:
With advances in wireless
technology and the ability to build smaller
and more efficient devices, our ability to
make diabetic life easier and more
comfortable is within grasp. The device I
came up with is similar to CGM monitors in
the sense that it can continuously measure
blood glucose levels but without any of the
prior problems of the CGM such as the
need to be calibrated and the lag time
from measurements of interstitial fluid. My
device, which I have labeled the
Continuous Intra-Arterial Blood Glucose
Monitor (CAGM), has two main parts to it,
a portion of the device inside the
subclavian artery and a portion of it
outside around the artery.
The subclavian artery was chosen because of the diameter of the artery as
well as its proximity to the heart, which will be further explained later. The
subclavian artery is located below the clavicle, where there is a convenient
amount of space for the portion of the device outside the artery (although the
device should be small enough so that it is not visible externally).
It is necessary to have both an external and internal part to the device
(relative to the artery, not to the body) because I do not want to hinder blood

Conceived by Wesley Cheng, 2106 Lindblad Ct, Arlington, Tx 76013 817-201-7975


Wcheng@nd.edu
Continuous Intra-arterial Blood Glucose Monitor (CAGM)

flow but at the same time I want a device that is able to power itself so that it is
not bulked up from a big battery. The external portion of the device is a
relatively flat rectangle that goes around the artery along with adjustable arms
to provide a snug fit so that it does not move around. The external portion is
where the glucose concentration will be determined as well as where the
information will be sent from via Bluetooth. The internal part of the device is
where the probe that that measures the glucose resides and also where the
source of energy is for the device.
In order to power the CAGM, a small turbine and energy generator will be
put inside the artery so that, with
each heartbeat, the CAGM is
powered. As the blood is pumped
from the aorta into the subclavian
artery, the blood that rushes past
rotates the turbine and generates
enough energy with to measure and
transmit data with the CAGM. This
natural harnessing of the body’s
energy allows for the CAGM to be
small and also have its own natural
rhythm of spontaneous transmission
that goes along with the body.
The reason I created the CAGM was because I wanted to abolish the pain
and hassle of diabetics always having to lance themselves to measure their blood
glucose levels. This device is great also because it can help both type 1 and type
2 diabetes in multiple ways. The reason why I chose transmission via Bluetooth
was because of our ever-growing array of electronics that are built in with
Bluetooth. With the CAGM, a diabetic could just carry around a cell phone with
special software installed onto it to check easily check his blood glucose level,
much like checking a text message. With more advanced cell phones such as the
iphone, a diabetic could even keep a very detailed history of how he’s doing and
customize his alerts and interface. Bluetooth can also communicate with personal
laptops so that a days history can be uploaded onto your computer and perhaps
then uploaded onto a website so that a dietician, doctor, or support group of
diabetics could view.

Conclusion:
With the availability of Bluetooth technology and downscaling of
electronics, the creation of this device should be relatively simple. The cost of
this device should not be too excessive but the process of installing it may be
difficult. I have thought about multiple ways including putting it in much like a
stent and then snapping on the outer portion onto the inner portion.
There is also a possibility of the inner portion of the CAGM causing
hemolysis but I believe that by refining the contour and shape of the parts inside
the artery can eliminate this concern. As for the material the CAGM will be
created out of, I believe an iron compound or some type of plastic polymer that
does not illicit an immune response would be most appropriate

Conceived by Wesley Cheng, 2106 Lindblad Ct, Arlington, Tx 76013 817-201-7975


Wcheng@nd.edu