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All: 1 Review: 0

1: J Surg Oncol. 1980;15(1):85-90. Links

Indomethacin and ascorbate inhibit desmoid tumors. Related Articles

Noncytotoxic drug therapy for intra-abdominal desmoid tumor in patients with

Waddell WR, Gerner RE. familial adenomatous polyposis. [D is Col on Rectum. 1992]

Administration of indomethacin caused complete resolution of a desmoid tumor after a partial response to Testolactone, sulindac, warfarin, and vitamin K1 for unresectable desmoid
tumors. [Am JSurg. 1991]
radiation. In another patient, this drug caused an immediate response, then became ineffective. When large
doses of ascorbic acid were given with indomethacin, slow resolution of the tumor began and has continued for The use of indomethacin, sulindac, and tamoxifen for the treatment of desmoid
14 months. Treatment of a third case with indomethacin and ascorbic acid from the beginning produced tumors associated with familial polyposis. [Cancer. 1987]
shrinkage of the tumor which has continued to date.
Review Successful treatment of a desmoid tumor with doxorubicin.
PMID: 7421272 [PubMed - indexed for MEDLINE] [Cancer. 1993]

Review Combined administration of ethodolac, ascorbic acid and radiotherapy

as adjuvant therapies in an extrathoracic desmoid tumor with gross [JBUON. 2006]

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Therapeutic utility of aspirin in the ApcMin/+ murine model of colon

carcinogenesis. [BMC Cancer. 2002]

Effects of sulindac on sporadic colorectal adenomatous polyps.

[ Gut. 1997]

Mesenteric mass in a 28-year-old woman.

[Postg rad Me dJ. 1997]

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Patient Drug Information

Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...) Ascorbic acid is used
to prevent and treat scurvy, a disease caused by a lack of vitamin C in the body.

Indomethacin (Indocin® ) Indomethacin is used to relieve moderate to severe

pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused
by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused ...

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Indomethacin and ascorbate inhibit desmoid tumors.

Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C.

Preventive action of vitamin C on nitrosamine formation.

Prolongation of survival times of terminal cancer patients by administration

of large dose...

Vitamin C and cancer: an overview.

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