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BIOGRAPHICAL SKETCH NAME SIVAKUMAR LOGANATHAN. M.Sc., Ph.D. EDUCATION/TRAINING INSTITUTION AND LOCATION DEGREE (if applicable) B.Sc. M.Sc.

YEAR(s) FIELD OF STUDY

Bharathiar University, India University of Madras, India

1992-1995 1996-1998

Zoology

Zoology Pharmacology & Environmental Toxicology Cancer Biology Cancer Biology

University of Madras, India

PhD

1998 – 2004 2004 -2005 2005 –2010

University of Pittsburgh Cancer Center. University of Chicago

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Title of the Ph.D. Thesis: Anticancer and Antioxidant effects of Solanum xanthocarpum alone and in combination with Cisplatin in N-Nitrosodiethylamine induced Hepatocellular carcinoma in rats. Positions: 2005 - 2010: Post Doctoral Research Associate, University of Chicago, USA. 2004 - 2005: Post Doctoral Research Associate, University of Pittsburgh Cancer Center, USA. 1999 - 2004: Research Fellow, Dr.ALM PGIBMS, University of Madras, India Awards/Honors:   Dr. Indira Vasudevan Award for the best research paper in cancer and its prevention for the year 2003 instituted by Indian Association of Biomedical Scientists (IABMS) conference held in Defense Research and Development Organization (DRDO) campus, Delhi, India. Travel Grants have been awarded by the Journal of Thoracic Oncology in Chicago Multidisciplinary Symposium in Thoracic Oncology 2008, Chicago, USA.
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PHS 398/2590 (Rev. 05/01)

2007-2011. Pharmacology and Toxicology. Natarajan V. First. Siddiqui SS. Biochemistry.SCLC and MPM. Middle):   Recipient of Tamilnadu state Government Scholarship for the year 2002. Vigneswaran H. Ecological Engineering. El-Hashani E. Molecular Biology. Pharmacology. Kindler HL. Cervantes G. ALM PG IBMS. NIH . Dept of Medicine. Husain AN.Role of c-Met in SCLC and potential for novel therapy (5RO1CA100750-06).Studies of a novel therapeutic target in non-small cell lung cancer (5RO1CA125541-03).Graduate and Undergraduate Courses in Biology. 05/01) Page 2/8 Continuation Format Page .elegans. Loganathan S. University of Madras: 2000 – 2003. Publications: 1. Role of protein kinase C β and vascular PHS 398/2590 (Rev. Recipient of UGC herbal sciences project award in 2003.International High throughput screen for modulators/small molecule inhibitors in C. Genetics. Patent: Pending .Principal Investigator/Program Director (Last. Salgia R. Physiology and Cell Biology at University of Chicago. Kanteti R. 20052009. 10/2004 – 11/2005: NCI . Vokes EE. Dr. Drug Delivery. University of Chicago. NIH .Dietary agents on pancreatic cancer (USPHS RO1CA106953). Tretiakova M. Supervisor PSOMER summer student’s research program for underrepresented mi nority communities: Pritzker School ofMedicine. Projects Investigated: 11/2005 – 2010: NIH . Molecular Biology.Role of Paxillin in lung cancer (5RO1CA129501-02). Lilly pharmaceuticals – Enzastaurin (LY317615) in thoracic malignancies – NSCLC. Membership in Professional Societies: 2004 – Present: Associate member in American Association for Cancer Research (AACR) 2004 – Present: American Association of Thoracic Oncology 2007 – Present: International Mesothelioma Interest Group (iMig) 2006 – Present: Mesothelioma Applied Reasearch Foundation (MARF) 2006 – Present: MicroRNA club. University of Chicago 2001 – 2005 : Indian Association of Biomedical Scientists (IABMS) Teaching Graduate Courses: Taught Graduate Courses in Genetics.

Cindy. Sattler M. Tretiakova MS. Salgia R. Deborah.89 (3):301-14. Ferguson MK. Protein kinase C beta in malignant pleural mesothelioma. Girard L. Krishnaswamy. Husain AN. Sivakumar. Middle): endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.Monit. invasion. Nallasura. Jagadeeswaran. Vokes EE. Sugarbaker D. Ravi. Nicolae DL. Benzyl isothiocyanate-induced DNA damage causes G2/M cell cycle arrest and apoptosis in human pancreatic cancer cells. Liang J. Tanguy Y. The role of pax transcription factors in lung carcinogenesis: relationship to c-Met receptor tyrosine kinase: P2-126. Garcia JG. Kanteti. J. Focal adhesion paxillin induces nodular cell growth. C. Krishnaswamy S. Loganathan S. 3. Soulii L. Loganathan S. Kanteti. Seiwert TY. Krausz T. Humphreys I. Aug 2007. Salgia R. Innocenti F. Minna J. Soundararajan. 2008 Jun. Kozloff MF. Ma PC. Ouyang Z. Rajani. Loganathan S. Schwartz S. Hasan. Anticancer Drugs. Zumba. J. Loganathan S. Everett E. Nallasura V. Singleton PA. Nallasura V. Clin Cancer Res. Salgia R. Osvaldo. 9. 8. Wang. Siddiqui SS. and angiogenesis in lung cancer: P2-124. Vokes EE. Rabia. Leonardo. Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion. Bindokas VP. Kanteti R. Sivakumar L and M P Balasubramanian.13 (3) 215-218(2003). 2009 Sep 15. Janamanchi V. August 2007. Aliya. Kindler HL. Jagadeeswaran R. 2008 Oct. Bueno R. 2008 Jan 1. Lang D. Ramnath N. PHS 398/2590 (Rev. Gordon GJ. Krishnaswamy S. Faoro L. Krishnaswamy S. 5. Natarajan V. Jagadeeswaran R. Faoro L.. Salgia.Ecotoxicol. 136 (11):2728-34.Environ.7 (6):856-63. Ramasamy. Ravi. Wang YC. Vidya. 4. Toxic and Sublethal effects of detergents on the freshwater fish Oreochromis mossambicus. 05/01) Page 3/8 Continuation Format Page . Faoro L. Seiwert. Loganathan S. Sattler M. 2 (8):S541. Loganathan. Liu W. Ecotoxicol. Husain AN. Westerhoff M. Ramasamy. J Carcinog. Sivakumar. Szeto LL. (Equal first author and Work was featured on the cover page of the journal). Natarajan V. Varalakshmi. Journal of Thoracic Oncology. 2006 Nov. 7. Salgia R.. Salgia. Husain AN. Cancer Res. Cancer Biol Ther. Srivastava SK. Loganathan S. Husain. Ethnic differences and functional analysis of MET mutations in lung cancer. Lab Invest. Krishnaswamy S.10:4. Antioxidant Property of Arogyavardhini. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. Modi R. Vokes EE. Wang YC. Zumba O. 11. Tretiakova M. Mackinnon AC. 2011 Mar 3.19 (9):841-8.15 (18):5714-23. elegans vulva phenotypes. Faoro L. 6. Seiwert T. Janamanchi. Vokes EE. Loganathan. Lingen MW. Zhang R.13 (4) 255-259 (2003). Faoro. Journal of Thoracic Oncology. Salgia R. 10. Ferguson MK. Rajani. Jagadeeswaran. Kanteti R. Kroll T. Lang. PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. Ahmed S.Principal Investigator/Program Director (Last. Reichman T. Tretiakova M. Minna J. Vokes. J Nutr.Environ. Duke-Cohan JS. Surawska H.Monit. Kanteti R. Vidya. an indigenous formulation on CCL4 induced liver in albino rats. Vigneswaran W. 2. Nallasura. First. Cagle P. 2(8):S540. 68 (1):132-42. Sivakumar L and M P Balasubramanian. 2009 Mar.

April 18-22. AACR Annual Meeting (Abstract #443). Contributed Papers at National. Loganathan S. USA 5. Loganathan and Sanjay K. 2008. elegans meeting. June 24-28. Sivakumar Loganathan. ASTRO 2008. Hedy Kindler. Everett Vokes. and the genetic–environmental interactions/effects of asbestos. 2009.Principal Investigator/Program Director (Last. Human MET and juxtamembrane domain mutations in lung cancer affect C. Chicago. Hedy Kindler. Soundararajan Krishnaswamy. International conferences & professional newsletters: 1. Ramasamy Jagadeeswaran.2009. Shahid S. Ravi Salgia. Tanguy Y. Nallasura V. Ramasamy Jagadeeswaran. Denver. Leonardo Faoro. Mesothelioma Applied Reasearch Foundation ( MARF) 2008. S. Shahid S. USA. 05/01) Page 4/8 Continuation Format Page . Varalakshmi Janamanchi. Expression and Function of PAX5 Transcription Factor and Regulation of c-MET in SCLC -Potential for Novel Biomarkers and Therapeutics. Kanteti R. The Netherlands. USA. 8. Ravi Salgia. Leo Faoro. Mesothelioma Applied Reasearch Foundation (MARF) 2007. Middle): 12. 4. USA. Krishnaswamy S. Ramasamy Jagadeeswaran Vokes EE. Leonardo Faoro. Siddiqui.elegans as a model system to evaluate genetic alterations in MPM. May 20-24. Aliya Husain. June 1-5. Chicago. Denver. A Craig Mackinnon. 11. Ravi Salgia. Chicago. Protein kinase c beta (PKC β) in malignant pleural mesothelioma. IL. Inhibition of PKC β in Malignant Pleural Mesothelioma (MPM). Ravi Salgia. Sivakumar Loganathan. Sixth congress of Lung cancer. USA. Expression and function of Pax 5 Transcription factor in SCLC. Shahid S. Ravi Salgia. Siddiqui. Sivakumar Loganathan. Salgia R. Amsterdam. Siddiqui. Sep 25-27. Sivakumar Loganathan. and Ravi Salgia.2007. Hanna Surawska. Srivastava (2011). C. Sivakumar Loganathan. Rajani Kanteti.elegans and synergize with nicotine:implications for cancer development. 25:18:25. 2009. Aliya Hussain… Sivakumar Loganathan et al. AACR Meeting LB119. Sivakumar Loganathan. 17 th International C. 6. Sivakumar Loganathan. Deborah Lang. 10. USA. 9. First. Everett Vokes. elegans vulva phenotypes: role of C. Soundararajan Krishnaswamy. 7. Germline c-Met Juxtamembrane domain mutations in lung cancer elicit abnormal vulval phenotypes in C. Chicago. Inhibition of TPA-1 protein kinase C by enzastaurin :implications for lung cancer and mesothelioma. IMIG. Sivakumar Loganathan. CO. Role of cMet in lung cancer. Ravi Salgia. elegans as a model organism for in vivo screening in cancer. Los Angeles. American Society of Clinical Oncology (ASCO). University of California. 2. ASTRO 2008. University of Chicago. Siddiqui. Trevor PHS 398/2590 (Rev. USA. CO. Expression of protein kinase C beta (PKCß) as a prognostic marker in malignant mesothelioma. Sivakumar Loganathan. Rajani Kanteti. Washington DC. 2008. Leonardo Faoro. USA. Phenethyl isothiocyanate induces apoptosis in human ovarian cancer cells by inhibiting EGFR/Akt pathway (Communicated). Faoro L. Maria Westerhoff. April 18-22. Ravi Salgia. 3. Seiwert. Shahid S.

16.28. 17. Mark W. Ruifen Zhang. Nallasura. AACR 2006 (Abstract #1314). Lioubov Soulii.Principal Investigator/Program Director (Last. 2002. Role of Cdc25C phosphatase in benzyl isothiocyanate-mediated G2/M arrest in pancreatic cancer cells. Sanjay K. India. Chennai. Thomas Krausz. Wickii Vigneswaran. 18. Jeffrey Richards. Viswanathan Natarajan. Chennai. Salgia. 15. Govt. Capsaicin induces apoptosis in human pancreatic cancer cells by activating mitochondrial death pathway. California. India. 05/01) Page 5/8 Continuation Format Page . Maria Tritiakova. Ravi. October 25. Aliya Hussain. Vytas P. Reichman. University of Madras. Anaheim. USA (Abstract #579). Vidya. Loganathan. Zumba. Salman Ahmed. 12. Lingen. Srivastava. “Solanum xanthocarpum extract alone and in combination with Cisplatin on cell membranes and derranged carbohydrate metabolism in NNitrosodiethylamine induced hepatocellular carcinoma in rats. Ravi Salgia. Ian Humphreys. 19. Sivakumar Loganathan.2003. Arumbakkam. Krishnaswamy. Krishnaswamy. 2006. CA. October 25-28. Mark K. R D Gomathi and M P Balasubramanian. Los Angeles. California. Osvaldo Zumba. 2006 14. Bindokas. The focal adhesion paxillin is a target for somatic mutations in lung cancer: implications for enhanced cell growth and invasion. Anticancer potentiating effect of ethanolic extract of Solanum xanthocarpum alone and in combination with Cisplatin in Nnitrosodiethylamine induced hepatocellular carcinoma in rats Indo-Australian Conference on Biotechnology in Medicine. Soundararajan…… Sivakumar Loganathan et al. Mutations and Functional Analysis of c-Met in Lung Cancer. Chicago. Soundararajan. USA. Antiproliferative effects of phenethyl Isothiocyanate against Human Ovarian Cancer Cells via Inhibition of Epidermal Growth Factor Receptor. Anaheim. Surawska. Varalakshmi. AACR Annual Meeting 2007(Abstract #358). Bangalore. IL. Seiwert. Trevor. The Fourth International Chicago Symposium on Malignancies of the Chest and Head & Neck. Jeffrey Richards. Role of reactive oxygen species in phenethyl isothiocyanate induced apoptosis in human ovarian cancer cells. Hanna. Sivakumar L. India. Therapeutic Targeting of c-MET in Lung Cancer Cell Lines and in Vivo Mouse Models. AACR Annual meeting 2005. Sivakumar L and Sanjay K Srivastava. AACR 2006 (Abstract #1313). Ramasamy. Everett E. Ferguson. Sanjay K. Janamanchi. Anaheim. First. Ruifen Zhang. Middle): Reichman. Anaheim. Feb. USA (Abstract # 5194). Biochemical changes in hepatopancreas and muscle of Penaeus monodon exposed to fenvaleratein National Symposium on Physiology and Biochemistry of Cultivable crustaceans. USA. Sivakumar L and M P Balasubramanian. 13. USA. Sivakumar L. Ian Humphreys and Sanjay K Srivastava. 20. Vidya Nallasura. California. The Fourth International Chicago Symposium on Malignancies of the Chest and Head & Neck. Indian Institute of Science (IISc). Vokes. Tanguy. Osvaldo. California. Jagadeeswaran.18-19. International Conference on the role of Indian systems of medicine and Homeopathy in the 21st Century” held in Chennai on February 12. Srivastava. 2004. Sivakumar Loganathan. AACR Annual meeting-2005. Feb 9-11. USA. Siddha Medical College and Hospital. PHS 398/2590 (Rev. Sivakumar. Livya Szeto. Sivakumar L and M P Balasubramanian.

Good Laboratory Practice in Life Sciences Research. First. University of Texas. Training programme to study the plant tissue Culture. 2009. blood and leucocyte culture. Chennai. University of Wisconsin. University of Madras. Anaheim. Department of Pharmacology and Environmental Toxicology. PHS 398/2590 (Rev. Chennai 6-7Jan 2004. stress.Principal Investigator/Program Director (Last. Delhi. AACR Annual meeting 2005. karyotyping and karyotype analysis from human blood and bone marrow aspirate samples at Cancer Institute (WIA) (Aug 2003). The Netherlands. 05/01) Page 6/8 Continuation Format Page . C. ALM PG IBMS. Denton. GLC. University of Madras. USA Science-2004 conference organized by the University of Pittsburgh. flame photometer at Shri A M M Murugappa Chettiar Research Center (March 2004).. USA. Science Fest 2003 -11 to 14 th Feb. ALM PG IBMS. pathogenesis and heterochrony C. Adyar. Denver. California. India. USA Retreat pharmacology 2005. India. India. Taramani. (2001). Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER). Amsterdam. India. USA. Dhanabagiyam Krishnaswamy Mudaliar College for Women. India. Indian Association of Biomedical Scientists (IABMS) 2002. India Conference organized by Indian Association of Biomedical Scientists (IABMS) 2003 2 -5th Nov. of Pharmacology. CO. Washington DC. Issues and Problems on Animal Experimentation a challenge to the medical research. Sep 25-27. Aug 10-25. Vellore. India. Chennai. G-banding. organized by Dept. Madison. elegans topic meeting #4. Taramani. Chennai. USA International Mesothelioma Interest Group (IMIG). Aug 3-6. Pondicherry. Training Programme on the tissue culture. Chennai. USA.elegans and genomics. Dr. chromosomal preparations. References: I will be happy to provide you with a list of references and additional information upon request. 6-8 th October 2004. Dr. University of Pittsburgh. Defense Research and Development Organization (DRDO) campus. 2008. AACR Annual meeting 2006. 2008. USA. Herbal sciences organized by University Grants Commission (UGC) and the University of Madras (2001). India. Middle): Conference/Seminar/Workshop participated: AACR Annual meeting 2009. HPLC. Aging.

PHS 398/2590 (Rev. 09901155477. Pin: 635207 Email: PETSIVA@GMAIL. First.Principal Investigator/Program Director (Last.COM Phone (Mobile):91 9566348735. 05/01) Page 7/8 Continuation Format Page . Middle): Personal Profile: Birth Date : 10th May 1975 Nationality : Indian Contact Address: 4/20 Kamarajar Nagar Uthangarai (PO & TK) Krishnagiri (DT).

05/01) Page 8/8 Continuation Format Page . Sincerely. I look forward to serving your institution.Tech Biotechnology students. s/d (Sivakumar) PHS 398/2590 (Rev. I have carried out advanced research for the in two of the world's best research institutes. I am writing this in response to your advertisement for faculty positions in your esteemed institution. First. Please let me know if you need additional details. I have considerable teaching and research experience in the field of biological sciences. publications in leading journals and possible collaborative research projects with pharmaceutical industries. I have enclosed my CV for your kind consideration.Principal Investigator/Program Director (Last. I have a number of novel hypotheses in the area of cancer medicine. I am also confident of getting funding from national and international agencies for research activities that would provide infrastructure support for M. I am confident that pursuit of my original ideas would lead to patents. I would like to offer myself for the position of Assistant Professor in Biotechnology. Middle): Dear Sir/Madam.