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Chethan Pandarinath, Ph.D.

Departments of Electrical Engineering & Neurosurgery  Stanford University  Stanford, CA
chethan [at] stanford [dot] edu  http://npl.stanford.edu/~chethan/
Education
2003-2010

Cornell University, Ithaca, NY
Ph.D. Electrical Engineering, Nov. 2010

2006

Marine Biological Laboratory, Woods Hole, MA
Methods in Computational Neuroscience

1998-2002

North Carolina State University, Raleigh, NC
B.S. Computer Engineering, B.A. Physics,
B.S. Science, Technology and Society, magna cum laude

Research Positions

Postdoctoral Fellow, Depts. of Electrical Engineering and Neurosurgery, Stanford University
(Mar. 2012-present). PIs: Jaimie Henderson, M.D., Krishna Shenoy, Ph.D.
Developing high-performance, reliable algorithms for Brain-Machine Interfaces. By extracting
signals from surgically implanted electrodes in human motor cortex, we aim to provide
accurate, high-speed control of computer cursors and assistive technologies such as robotic
arms. Currently testing these devices with persons with tetraplegia as part of the BrainGate2
FDA Pilot Clinical Trial.

Postdoctoral Fellow, Dept. of Physiology and Biophysics, Weill Cornell Medical College
(Nov. 2010-Feb. 2012). PI: Sheila Nirenberg, Ph.D.
Developed a novel prosthetic approach for vision restoration. The approach combines
algorithms that replicate the retina’s neural code with high-resolution optogenetic stimulation
of retinal ganglion cells.

Graduate Researcher, Depts. of Electrical Engineering / Physiology and Biophysics, Cornell
University (2005-2010). PI: Sheila Nirenberg, Ph.D.
Thesis: “A novel mechanism for switching a neural system from one state to another”

Undergraduate Researcher, Dept. of Physics, NC State University (2002-2003), PI: Robert
Nemanich, Ph.D.

Publications

UE Ukaegbu, SP Kishore, DL Kwiatkowski, C Pandarinath, N Dahan-Pasternak, R
Dzikowski, KW Deitsch. (2014) Recruitment of PfSET2 by RNA polymerase II to variant
antigen encoding loci contributes to antigenic variation in P. falciparum. PLOS Pathogens,
Jan;10(1):e1003854. doi: 10.1371/journal.ppat.1003854

C Pandarinath, ET Carlson, S Nirenberg. (2013) A system for optically controlling neural
circuits with very high spatial and temporal resolution, in Proceedings of the IEEE 13th
International Conference on Bioinformatics and Bioengineering (BIBE), Nov 10-13, 2013,
Chania, Greece. doi: 10.1109/BIBE.2013.6701707

S Nirenberg, C Pandarinath (2012) A retinal prosthetic strategy with the capacity to restore
normal vision. Proceedings of the National Academy of Sciences. Sept 11; 109(37):15012-7.
doi: 10.1073/pnas.1207035109

C Pandarinath, JD Victor, S Nirenberg (2010) Symmetry breakdown in the ON and OFF
pathways of the retina at night: functional implications. Journal of Neuroscience, July 28;
30(30):10006-14. doi: 10.1523/jneurosci.5616-09.2010

C Pandarinath, I Bomash, JD Victor, GT Prusky, WW Tschetter, S Nirenberg (2010) A novel
mechanism for switching a neural system from one state to another. Frontiers in
Computational Neuroscience, Mar 4:2. doi: 10.3389/fncom.2010.00002

K Dedek, C Pandarinath, NM Alam, K Wellershaus, T Schubert, K Willecke, GT Prusky, R
Weiler, S Nirenberg (2008) Ganglion cell adaptability: Does the coupling of horizontal cells
play a role? PLoS ONE, 3(3): e1714. doi: 10.1371/journal.pone.0001714

BJ Coppa, CC Fulton, SM Kiesel, RF Davis, C Pandarinath, JE Burnette, RJ Nemanich, DJ
Smith (2005) Structural, microstructural, and electrical properties of gold films and Schottky
contacts on remote plasma cleaned, n-type ZNO{0001} surfaces. Journal of Applied Physics,
97:103571. doi: 10.1063/1.1898436

WJ Mecouch, BP Wagner, ZJ Reitmeier, RF Davis, C Pandarinath, BJ Rodriguez, RJ
Nemanich (2004) Preparation and characterization of atomically clean stoichiometric surfaces
of AlN(0001). Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films,
23:1. doi: 10.1116/1.1830497

Patents

JC Kao, C Pandarinath, P Nuyujukian, KV Shenoy (2013) Brain-Machine Interface Utilizing
Interventions to Emphasize Aspects of Neural Variance. US Provisional Application No.
61/837,014 (filed June 19, 2013).

S Nirenberg, C Pandarinath, I Ohiorheneun (2012) Retina Prosthesis. International Patent
W02012030625

S Nirenberg, C Pandarinath, I Ohiorheneun (2011) Retina Prosthesis. International Patent
W02011106783

Research Support

2013-2015 Optimizing human BMI performance through insights gained from non-human
primate research. Postdoctoral Fellowship, Craig H. Neilsen Foundation for Spinal Cord
Injury Research.

2013 Dean’s Fellowship, Stanford University.

2011 Co-Principal Investigator, A retinal prosthetic strategy with the capacity to restore
normal vision. BioAccelerate NYC Prize, awarded by the New York City Investment Fund.

Presentations

C Pandarinath, V Gilja, CH Blabe, B Jarosiewicz, JA Perge, LR Hochberg, KV Shenoy, JM
Henderson (2014) High-performance communication using neuronal ensemble recordings
from the motor cortex of a person with ALS. American Society for Stereotactic and Functional
Neurosurgery, Washington, D.C. 92 (suppl 1) 1-75, #130. (Selected talk)

C Pandarinath, V Gilja, CH Blabe, LR Hochberg, KV Shenoy, JM Henderson (2014)
Corresponding neural signatures of movement and imagined movement in human motor
cortex. Computational and Systems Neuroscience (COSYNE), Salt Lake City, UT. III-87
(Poster)

C Pandarinath, V Gilja, CH Blabe, LR Hochberg, KV Shenoy, JM Henderson (2013)
Overlapping neural representations of upper extremity movements in human primary motor
cortex during volitional, imagined, observed, and passive movements. Society for
Neuroscience, San Diego, CA (Poster)

V Gilja, C Pandarinath, CH Blabe, LR Hochberg, KV Shenoy, JM Henderson (2013) Design
and application of a high performance intracortical brain computer interface for a person with
amyotrophic lateral sclerosis. Society for Neuroscience, San Diego, CA (Poster)

C Pandarinath, S Nirenberg (2010) A retinal prosthetic strategy with the capacity to restore
normal vision: quantifying the effects of the encoder and transducer. Society for
Neuroscience, San Diego, CA (Poster)

S Nirenberg, C Pandarinath (2010) A retinal prosthetic strategy with the capacity to restore
normal vision. Society for Neuroscience, San Diego, CA (Talk)

S Nirenberg, C Pandarinath, I Bomash, JD Victor, GT Prusky, WW Tschetter (2010) A novel
role for gap junction coupling: a mechanism for allowing neural networks to change states.
Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL (Poster)

C Pandarinath, JD Victor, S Nirenberg (2009) Symmetry breakdown in the ON and OFF
pathways of the retina at night: functional implications. Society for Neuroscience, Chicago, IL
(Poster)

S Nirenberg, C Pandarinath, I Bomash, JD Victor, GT Prusky, WW Tschetter (2009) A novel
role for gap junction coupling: a mechanism for allowing neural networks to change states.
Society for Neuroscience, Chicago, IL (Poster)

S Nirenberg, C Pandarinath, I Bomash, JD Victor, WW Tschetter (2009) How neural systems
adjust to different environments: an intriguing role for gap junction coupling. Computational
and Systems Neuroscience (COSYNE), Salt Lake City, UT (Selected talk)

C Pandarinath, K Dedek, NM Alam, K Wellershaus, T Schubert, K Willecke, GT Prusky, R
Weiler, S Nirenberg (2007) Ganglion cell adaptability: Does the coupling of horizontal cells
play a role? Society for Neuroscience, San Diego, CA (Poster)

Teaching Experience



Head Teaching Assistant, Designing with Microcontrollers, Cornell (2005)
Teaching Assistant, Introduction to Microelectronics, Cornell (2003-2004)
Teaching Assistant, Introduction to Circuits, Cornell (2003-2004)
Teaching Assistant, Introduction to Computing, NCSU (2001)

Honors/Awards








Fellow, Craig H. Neilsen Foundation for Spinal Cord Injury Research (2013-2015)
Dean’s Fellowship, Stanford University (2013)
Fellow, Tri-Institutional Training Program in Vision Research (2005-2009)
Honorable Mention, NSF Graduate Research Fellowship (2003)
Benjamin Franklin Scholar, NCSU (1998-2002)
Leaders in Networking Scholarship, AT&T (2001)
Philip B. Jackson Engineering Scholarship, NCSU (2001)
Gregory Poole Engineering Scholarship, NCSU (2000)
Dean's List, NCSU (1998-2002)

Skills

Programming: C/C++, MATLAB/Simulink, Python, ARM/DSP embedded systems, Real-time
Linux, Atmel microcontrollers, OpenCV, Perl, PHP, Java, HTML/Javascript
Quantitative analysis: Pattern classification, Bayesian/Maximum-Likelihood decoding, neural
response analysis, linear/non-linear modeling, digital filtering/signal processing

Research techniques: Clinical studies, multi-electrode electrophysiology, optogenetic
stimulation, mouse survival surgery, optokinetic behavioral assays, retinal dissection,
histology, breeding, genotyping

Work Experience


Intel Corporation, Hardware Validation, Chandler, AZ (May-August 2002)
Billions of Operations per Second, Compiler Design, Chapel Hill, NC (May–August 2000)
IBM Corporation, Mainframe Division, Raleigh, NC (May-August 1999)

Citizenship: U.S. Citizen
References
Jaimie M. Henderson, M.D.
Associate Professor, Dept. of Neurosurgery
Stanford University
300 Pasteur Drive Rm 227, Stanford, CA
(650) 723-5574
henderj@stanford.edu
Krishna Shenoy, Ph.D.
Professor, Dept. of Electrical Engineering
Stanford University
W100-A, James H. Clark Center
318 Campus Drive West, Stanford, CA
(650) 723-4789
shenoy@stanford.edu
Sheila Nirenberg, Ph.D.
Professor, Dept. of Physiology and Biophysics
Weill Medical College of Cornell University
C-504B, 1300 York Ave, New York, NY
(212) 746-6372
shn2010@med.cornell.edu
Jonathan D. Victor, M.D., Ph.D.
Professor, Dept. of Neurology and Neuroscience
Weill Medical College of Cornell University
LC-807, 1300 York Ave, New York, NY
(212) 746-2343
jdvicto@med.cornell.edu