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Cumulartive Designated Products as of: 10/3/2007

total designated products: 1749
Trade Name
Valortim

Generic Name

Designated Indication
Treatment of anthrax infection Prevention of serious adverse events associated with vascular leak syndrome caused by Interleukin-2 therapy

(+/-)-7-[3-(4-acetyl-3-methoxy-2propylphenoxy)propoxy]-3,4-dihydro-8-propyl2H-1-benzopyran-2-carboxylic acid (1R,2S) 6-bromo-alpha-[2(dimethylamino)ethyl]-2-methoxy-alpha-(1naphthyl)-beta-phenyl-3-quinolineethanol (1S)-1-(9-deazahypoxanthin-9-yl)-1,4dideoxy-1,4-imino-D-ribitol-hydrochloride (1S)-1-(9-deazahypoxanthin-9-yl)-1,4dideoxy-1,4-imino-D-ribitol-hydrochloride (1S)-1-(9-deazahypoxanthin-9-yl)-1,4dideoxy-1,4-imino-D-ribitol-hydrochloride (2Z)-2-cyano-3-3hydroxy-N-[4(trifluoromethly)phenyl]-2-hepten-6-ynamide (3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazole-3-yl]benzoic acid (3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazole-3-yl]benzoic acid) (3S)-3-(4-trifluoromethoxybenzyloxy)-6-nitro2H-3,4-dihydroimidazo[2,1-b]oxazine (3S)-3-[(2S)-2-({N-[2-tertbutyl)phenyl]carbamoyl}carbonylamino) propanoylamino]-4-oxo-5-(2,3,5,6tetrafluorophenoxy) pentanoci acid (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14tetrahydro-1-H-pyrano[3?,4?:6,7]-indolizino[1,2-b]-quinoline-11-carbaldehyde O-(tertbutyl)-(E)-oxime (6R,S)5,10-methylene-tetrahydrofolic acid (9-[N-(3-morpholinopropyl)-sulfonyl]-5,6dihydro-5-oxo-11-H-indeno [1,2-c] isoquinoline methanesulfonic acid (R)-2-methyl-6-nitro-2-{4-[4-(4trifluoromethoxyphenoxy)piperidin-1yl]phenoxymethyl}-2,3-dihydroimidazo[2,1b]oxazole (R)-N-[2-(6-chloro-5-methoxy-1H-indol-3yl)propyl]acetamide (R)-N-[2-(6-Chloro-methoxy-1H-indol3yl)propyl]acetamide (UDU-stereoisomer of c-UJUun UNU-terminal UkUnhibitor) [5,10,15,20-tetrakis(1,3-diethylimidazolium-2yl)porphyrinato] manganese(III)pentachloride 1,1'-[1,4-phenylenebis(methylene)-bis1,4,8,11-tetraazacyclotetradecan

Treatment of pulmonary tuberculosis (active disease) Treatment of chronic lymphocytic leukemia and related leukemias to include prolymphocytic leukemia, adult T-cell leukemia, and hairy cell leukemia

Treatment of acute lymphoblastic leukemia

Treatment of T-cell non-Hodgkin's lymphoma

FK778

Prevention of acute rejection following kidney, heart, and liver tranplantation For use in the treatment of cystic fibrosis resulting fron a nonsense (premature stopcodon) mutation in the cystic bibrosis transmembrane conductance regulatory gene. Treatment of Muscular Dystrophy resulting from premature stop mutations in the dystrohin gene.

Treatment of tuberculosis.

Treatment of patients undergoing solid organ transplantation.

Gimatecan CoFactor

Treatment malignant glioma For use in combination with 5-fluorouracil for the treatment of patients with pancreatic cancer Prevention of post-operative complications of aortic anuerysm surgical repair

Treatment of pulmonary tuberculosis. Treatment of circadian rhythm sleep disorders in blind people with no light perception Treatment of neuroleptic-induced tardive dyskinesia in schizophrenia patients

Treatment of acute sensorineural hearing loss

Treatment of Amyotrophic Lateral Sclerosis For use to improve the yield of progentor cells in the apheresis product for subsequest stem cell transplantation following myelosuppressive or myeloablative chemotherapy

1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2[(methylamino)carbonyl]hydrazine

Cloretazine

Treatment of acute myelogenous leukemia

1,5-(Butylimino)-1,5 dideoxy,D-glucitol

Treatment of Fabry's disease. Treatment of somatostatin receptor positive neuroendocrine tumors.

111Indium pentetreotide

SomatoTher

166Ho-DOTMP

Treatment of multiple myeloma.

17 a-Hydroxyprogesterone caproate 17-alltlamino-17-demethoxygeldanamycin (17-AGG) 17-allylamino-17-demethoxygeldanamycin (17-AGG)

Gestiva

Prevention of preterm birth in singleton pregnancies

Treatment of multiple myeloma.

For the treatment of chronic myelogenous leukemia

1-Deoxygalactonojirimycin

Treatment of Fabry Disease

1-dexynojirimycin hydrochloride 2-(3,5-dichloro-phenyl)-benzoxazole-6carboxylic acid 2-(3-diethylaminopropyl)-8,8-dipropyl-2azaspiro [4,5] decan dimaleate 2-(3-Diethylaminopropyl)-8,8-dipropyl-2azaspiro[4,5] decane dimaleate

Treatment of Pompe disease

Treatment of familial amyloid polyneuropathy Treatment of mulitple myeloma and associated bone resorption

Atiprimod

Atiprimod

Treatment of carcinoid tumors

2',3',5'-tri-o-acetyluridine 2-0-Butyryl-1-0-octyl-myo-inositol 3,4,5,6tetrakisphosphate

Treatment of mitochondrial disease

Treatment of cystic fibrosis

2-0-desulfated heparin

Aeropin

Treatment of cystic fibrosis.

20-mer complementary to Akt mRNA 20-mer oligonucleotide complementary to Akt mRNA 20-mer oligonucleotide complementary to Akt mRNA 20-mer oligonucleotide complementary to Akt mRNA

Treatment of stomach cancer

Treatment of pancreatic cancer

Treatment of glioblastoma

Treatment of renal cell carcinoma

20-mer oligonucleotide complementary to Akt mRNA

Treatment of ovarian cancer

2'-3'-dideoxyadenosine

Treatment of aquired immunodeficiency syndrome.

24,25 dihydroxycholecalciferol

Treatment of uremic osteodystrophy.

2-chloroethyl-3-sarcosinamide-1-nitrosourea

Treatment for malignant gliomas

2-chloroethyl-3-sarcosinamide-1-nitrosourea 2'-deoxycytidine

Sarmustine

Treatment for malignant glioma As a host-protective agent in the treatment of acute myelogenous leukemia.

2-methoxyestradiol

PulmoLAR

Treatment of pulmonary arterial hypertension

2-methoxyestradiol

Panzem NCD

Treatment of ovarian cancer

2-methoxyestradiol

Panzem

Treatment of multiforme glioblastoma

2-methoxyestradiol 2'-O-methyl-phosphorothiolate oliogribonucleotide 3-(3,5-Dimethyl-1H-2ylmethylene)-1,3dihydro-indol-2-one 3-(3,5-dimethyl-1H-2ylmethylene)-1,3-dihydroindol-2-one

Panzem

Treatment of multiple myeloma

Treatment of Duchenne muscular dystrophy

Treatment of von Hippel-Lindau disease.

Treatment of Kaposi's sarcoma.

3,4-diaminopyridine 3,5,3'-triiodothyroacetate

Treatment of Lambert-Eaton myasthenic syndrome. Treatment of well-differentiated papillary, follicular or combined papillary/follicular carcinomas of the thyroid gland.

3'-azido-2',3'dideoxyuridine 4-(2-fluorophenyl)-6-methyl-2-(1-piperzinyl) 4-(3-Methanesulfonyl-phenyl)-1propylpiperidine HCl

AZDU

Treatment of acquired immunodeficiency syndrome. Treatment of Chronic Functional Vomiting to include functional vomiting and cyclic vomiting syndrome.

Treatment of Huntington disease.

4,5-dibromorhodamine 123

Theralux Irradiation Device chronic myelogenous leukemia Treatment of
Treatment of chronic iron overload resulting from conventional transfusional treatment of betathalassemia major and sickle cell anemia.

40SD02

4-Amino-1-[5-O-[(2R, 4S)-2-oxido-4-(4pyridinyl)-1, 3, 2-dioxaphosphorinan-2-yl]-b-Darabinofuranosyl]-2(1H)-pyrimidinone 4-Aminopyridine 4-aminosalicylic acid 4-aminosalicylic acid

Treatment of hepatocellular carcinoma. Treatment chronic functional motor and sensory deficits from Guillain-Barre syndrome

Paser Granules ileo-cecal Crohn's disease

Treatment of acute flares in pediatric patients with Treatment of mild to moderate ulcerative colitis in

Pamisyl (P-D), Rezipas (Squibb) to sulfasalazine. patients intolerant

4-cholest-en-3-one, oxime 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1[dimethylamino)acetyl]-4-piperidinyl]phenyl]1H-imidazole-2-carboxamide monohydrochloride 4-trifluoromethyl-N-(3.3a.4.4a.5,5a,6,6aoctahydro-1,3-dioxo4,6ethenocycloprop[f]isoindol-2(1H)-yl)benzamide 4-trifluoromethyl-N-(3.3a.4.4a.5,5a,6,6aoctahydro-1,3-dioxo4,6ethenocycloprop[f]isoindol-2(1H)-yl)benzamide

Treatment of amyotrophic lateral sclerosis

Treatment of acute myeloid leukemia

Treatment of smallpox.

post exposure prophylaxis against smallpox

5(S)-(2'-hydroxy ethoxy)-20(S)-Camptothecin 5,12-Naphthacenedione, 10-[[3-amino-2,3,6trideoxy-4-O-(phenylmethyl)-a-L-lyxohexopyranosyl]oxy]-7,8,9,10-tetrahydro6,8,11-trihydroxy-8-(hydroxyacetyl)-1methoxy-, hydrochloride, (8S,10S)- (9CI) 5,5',5"-[Phosphinothioylidyne-tris(imino-2,1ethanediyl)]tris[5methylchelidoninium]trihydroide hexahydrochloride

Treatment of osteosarcoma (bone cancer)

Treatment of malignant gliomas

Treatment of pancreatic cancer

5,6-dihydro-5-azacytidine 5,7-dihydroxy-3-(4-hydroxyphenyl)-chromen4-one

Treatment of malignant mesothelioma.

Prevention of acute radiation syndrome

506U78 5a8, monoclonal antibody to CD4

Treatment of chronic lymphocytic leukemia. For use in post-exposure prophylaxis for occupational exposure to human immunodeficiency virus.

5-aza-2'-deoxycytidine

Treatment of acute leukemia.

5-hydroxymethyl-2-furfuraldehyde

Treatment of sickle cell disease

5-iodo-2-pytimidinone-2'-deoxyribose 5-methyl-1-phenyl-2-(1H)-pyridone(CAS 53179-13-8)

Treatment of malginant glioma

Pirfenidone

Treatment of idiopathic pulmonary fibrosis

6,8-bis-benzylsulfanyl-octanoic acid

Treatment of pancreatic cancer

6-hydroxymethylacylfulvene

Treatment of histologically confirmed advanced or metastatic pancreatic cancer.

8 Cyclopentyl 1,3-dipropylxanthine 8-methoxsalen

Treatment of cystic fibrosis.

Uvadex

For use in conjunction with the UVAR photopheresis to treat diffuse systemic sclerosis. For the prevention of acute rejection of cardiac allografts.

8-methoxsalen

Uvadex

90Y-hPAMA4 9-cis-retinoic acid

PAN-Cide

Treatment of pancreatic cancer Prevention of retinal detachment due to proliferative vitreoretinopathy.

9-nitro-20-(S)-camptothecin

Treatment of pancreatic cancer.

9-nitro-20-(S)-camptothecin

Camvirex

Treatment of pediatric HIV infection/AIDS

a-(3-aminophthalimido) glutaramide

Actimid

Treatment of multiple myeloma

A10 & AS2-1 Antineoplaston

Treatment for patients with brain stem glioma

Abetimus

Treatment of lupus nephritis.

ACA125 Acetylcysteine

Treatment of epithelial ovarian cancer

Mucomyst/Mucomyst 10 IV severe acetaminophen overdose. moderate to

Intravenous treatment of patients presenting with

acetylcysteine

Acetadote

For the intravenous treatment of moderate to severe acetaminophen overdose

Acid sphingomyelinase

Treatment of Niemann-Pick disease type B.

Aconiazide

Treatment of tuberculosis.

Adalimumab

Humira

Treatment of pediatric Crohn's disease.

Adalimumab Adeno-associated vector expressing the human lipoprotein lipase protein Adeno-associated viral vector containing the gene for human coagulation factor IX

Humira

Treatment of juvenile rheumatoid arthritis

Treatment of lipoprotein lipase deficiency

Coagulin-B

Intramuscular treatment of patients with moderate to severe hemophilia

Adeno-associated viral vector containing the gene for human coagulation factor IX Adeno-associated viral vector expressing human acid alpha glucosidase gene adeno-associated viral vector expressing human retinoschisin-1 gene Adeno-associated viral-based vector cystic fibrosis gene therapy

Coagulin-B

Intrahepatic treatment of patients with moderate to severe hemophilia

Treatment for Pompe disease

Treatment of X-linked juvenile retinoschisis (XLRS).

Treatment of cystic fibrosis. For use in conjunction with BCNU in the treatment of brain tumors.

Adenosine Adenoviral vector expressing Herpes simplex virus thymidine kinase gene Adenovirus-based vector Factor VIII complementary DNA to somatic cells adenovirus-mediated herpes simplex virusthymidine kinase gene

Treatment of malignant brain tumors

MiniAdFVIII

Treatment of hemophilia A. Use with gancyclovir in the treatment of malignant glioma Treatment of respiratory syncytial virus lower respiratory tract disease.

Aerosolized pooled immune globulin

a-Galactosidase A

Plant-Produced Human a-Glactosidase A Treatment of Fabry's disease

Aglycosyl anti-CD3 monoclonal antibody

Treatment of new-onset type I diabetes mellitus

AI-RSA

Albendazole

Albenza

Treatment of autoimmune uveitis. Treatment of neurocysticercosis due to Taenia solium as: 1) chemotherapy of parenchymal, subarachnoidal and racemose (cysts in spinal fluid) neurocysticercosis in symptomatic cases and 2) prophylaxis of epilepsy and other sequelae in asymptomatic neurocys Treatment of hydatid disease (cystic echinococcosis due to E. granulosus larvae or alveolar echinococcosis due to E. multilocularis larvae).

Albendazole

Albenza

Albuterol Aldesleukin

Prevention of paralysis due to spinal cord injury

Proleukin

Treatment of primary immunodeficiency disease associated with T-cell defects.

Aldesleukin

Proleukin

Treatment of metastatic renal cell carcinoma.

Aldesleukin

Proleukin

Treatment of metastatic melanoma.

Aldesleukin

Proleukin

For the treatment non-Hodgkin's lymphoma.

alemtuzumab alendronate

Campath Fosamax

Treatment of chronic lymphocytic leukemia. Treatment of osteogenesis imperfecta in pediatric patients 4 years of age and older Treatment of the bone manifestations of Gaucher disease

Alendronate disodium

Fosamax

Alfentanil

Management of postherpetic neuralgia

Alfentanil Alglucerase injection

Treatment of painful HIV-associated neuropathy

Ceredase

Replacement therapy in patients with Type II and III Gaucher's disease.

Alglucerase injection Alitretinoin

Ceredase Panretin

For replacement therapy in patients with Gaucher's disease type I. Topical treatment of cutaneous lesions in patients with AIDS-related Kaposi's sarcoma.

Alitretinoin allantoin Allogeneic human retinal pigment epithelial cells on gelatin microcarriers

Panretin Alwextin

Treatment of acute promyelocytic leukemia Treatment of skin blistering and erosions associated with inherited epidermolysis bullosa Treatment of Hoehn and Yahr stage 3 and 4 Parkinson's disease.

Spheramine

Allogeneic peripheral blood mononuclear cells sensitized against patient alloantigens by CYTOIMPLANT Treatment of pancreatic cancer mixed lymphocyte culture Allogeneic retinal epithelial cells transfected with plasmid vector expressing ciliary neurotrophic growth factor Allogeneic T-cells cultured with anti-CD3 and IL-2; transduced with retroviral vector (SFCMM-3), expressing herpes simplex 1 virus-thymidine kinase (HSV-TK) and truncated low affinity nerve growth factor receptor; selected with anti-low affinity nerve gro

Treatment of retinitis pigmentosa

Immunotherapy for acceleration of T-cell reconstitution in patients undergoing allogeneic hematopoietic stem cell transplantation

Allopurinol riboside

Treatment of cutaneous and visceral leishmaniasis.

Allopurinol riboside

Allopurinol sodium

Treatment of Chagas' disease. Management of patients with leukemia, lymphoma, and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels and who cannot tolerate oral Aloprim for Injection therapy.

Allopurinol sodium

Ex-vivo preservation of cadaveric kidneys for transplantation

Alpha-1-acid glycoprotein

Treatment of cocaine overdose

Alpha-1-acid glycoprotein Alpha-1-antitrypsin (recombinant DNA Origin) Alpha1-Proteinase Inhibitor (Human)

Treatment of tricyclic antidepressant poisoning As supplementation therapy for alpha-1-antitrypsin deficiency in the ZZ phenotype population. Inhalation therapy for the the treatment of congential deficiency of alpha1-proteinase inhibitor.

Alpha1-Proteinase Inhibitor (Human) Alpha1-proteinase inhibitor (human)

ARC-API

Treatment of cystic fibrosis For slowing the progression of emphysema in alpha1antitrypsin deficient patients. For replacement therapy in the alpha-1-proteinase inhibitor congenital deficiency state.

Alpha1-proteinase inhibitor (human)

Prolastin

Alpha-galactosidase A

Fabrase

Treatment of Fabry's disease. Treatment of alpha-galactosidase A deficiency Long-term enzyme replacement therapy for the treatment of Fabry disease. Prevention and treatment of intrinsic acute renal failure due to ischemia. Treatment of inherited mitochondrial respiratory chain diseases Treatment of severe peripheral arterial occlusive disease (critical limb ischemia) in patients where other procedures, grafts or angioplasty, are not indicated.

Alpha-galactosidase A Alpha-galactosidase A Alpha-melanocyte stimulating hormone

CC-galactosidase (Fabry's disease). Replagal

Alpha-tocopherol quinone

Alprostadil alteplase

Activase

Treatment of intraventricular hemmorage associated with intracerebral hemmorrhage

Altretamine Alvocidib

Hexalen

Treatment of advanced adenocarcinoma of the ovary. Teatment of B-cell chronic lymphocytic leukemia (BCLL) or prolymphocytic leukemia arising from CLL.

ambrisentan

Letairis

Treatment of pulmonary arterial hypertension

AMG 531

Treatment of immune thrombocytopenic purpura.

Amifostine Amifostine Amifostine Amifostine

Ethyol Ethyol Ethyol Ethyol

Treatment of myelodysplastic syndromes. For use as a chemoprotective agent for cisplatin in the treatment of metastatic melanoma. for For use as a chemoprotective agent cyclophosphamide in the treatment of advanced ovarian carcinoma.

For use as a chemoprotective agent for cisplatin in the treatment of advanced ovarian carcinoma.

Amifostine Amifostine Amikacin

Ethyol Ethyol

Reduction of the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer. For the reduction of the incidence and severity of toxicities associated with cisplatin administration. Treatment of bronchopulmonary Pseudomonas

SLIT Amikacin aeruginosa infections in cystic fibrosis patients

Amiloride HCl solution for inhalation

Treatment of cystic fibrosis. For the topical treatment of traumatic hyphema of the eye.

Aminocaproic acid

Caprogel

Aminolevlinic acid hydrochloride

Levulan

Treatment of esophageal dysplasia

Aminosalicylate sodium

Treatment of Crohn's disease.

Aminosalicylic acid

Paser Granules Treatment of tuberculosis infections

Aminosidine

Paromomycin

Treatment of visceral leishmaniasis

Aminosidine

Paromomycin

Treatment of visceral leishmaniasis (kala-azar).

Aminosidine

Gabbromicina

Treatment of tuberculosis.

Aminosidine

Gabbromicina

Treatment of Mycobacterium avium complex.

Amiodarone

Amio-Aqueous Treatment of incessant ventricular tachycardia.
For the acute treatment and prophylaxis of lifethreatening ventricular tachycardia or ventricular fibrillation.

Amiodarone HCl

Cordarone

Ammonium tetrathiomolybdate

Coprexa

Treatment of Wilson's disease.

amonafide L-malate

Xanafide

Amphotericin B inhalation powder

Treatment of acute myeloid leukemia. Prevention of pulmonary fungal infections in patients at risk for aspergillosis due to immunosuppressive therapy including those receiving organ or stem cell transplants, or teated with chemotherapy or radiation for hematologic malignancies

Amphotericin B lipid complex

Abelcet

Treatment of invasive protothecosis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive sporotrichosis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive coccidioidomycosis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive zygomycosis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive candidiasis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive fungal infections.

Amsacrine

Amsidyl

Treatment of acute adult leukemia.

Amyl nitrite, sodium nitrite, sodium thiosulfate Cyanide Antidote Kit Treatment of cyanide poisoning Treatment of thrombocytosis in chronic myelogenous leukemia.

Anagrelide

Agrylin

Anagrelide

Agrylin

Treatment of essential thrombocythemia.

Anagrelide

Agrylin

Treatment of polycythemia vera.

Ananain, comosain

Vianain

For the enzymatic debridement of severe burns.

Anaritide acetate Anaritide acetate

Auriculin Auriculin

Treatment of patients with acute renal failure. Improvement of early renal allograft function following renal transplantation. Treatment of patients having experienced a severe traumatic brain injury (Glasgow Coma Scale 3 to 8) in order to decrease early mortality and improve longTo establish and maintain anticoagulation in heparinterm functional and neurological outcome intolerant patients undergoing cardiopulmonary bypass.

Anatibant Ancrod

Viprinex

Angiotensin 1-7 Angiotensin 1-7 Anti pan T lymphocyte monoclonal antibody Anti pan T lymphocyte monoclonal antibody antiangiogenic components extracted from marine cartilage

MARstem

Treatment of myelodysplastic syndrome Treatment of neutropenia associated with autologous bone marrow transplantation.

Anti-t Lymphocyte Immunotoxin Xmmly-h65-rta potential bone marrow grafts.

For ex-vivo treatment to eliminate mature T cells from For in-vivo treatment of bone marrow recipients to

Anti-t Lymphocyte Immunotoxin Xmmly-h65-rta prevent graft rejection and graft versus host disease.

Neovastat (AE-941) Treatment of renal cell carcinoma

anti-CD23 IgG1, kappa monoclonal antibody

Treatment of chronic lymphocytic leukemia

Anti-CD40 mAb

Treatment of chronic lymphocytic leukemia

Anti-CD45 monoclonal antibodies Anti-CEA Sheep-human chimeric monoclonal antibody labeled w/iodine-131 (KAb201) Anti-cytomegalovirus monoclonal antibodies Anti-cytomegalovirus monoclonal antibodies Anti-cytomegalovirus monoclonal antibodies Anti-cytomegalovirus monoclonal antibodies Anti-cytotoxic T lymphocyte antigen 4 monoclonal antibody Antiepilepsirine

Prevention of acute graft rejection of human organ transplants.

Treatment of pancreatic cancer Prevention of human cytomegalovirus infection in bone marrow and organ transplant patients. Treatment of human cytomegalovirus infection in bone marrow and organ transplant patients. Prevention of human cytomegalovirus infection in patients diagnosed with AIDS. Treatment of human cytomegalovirus infection in patients diagnosed with AIDS. Treatment of stage IIb to stage IV metastatic melanoma Treatment of drug resistant generalized tonic-clonic epilepsy in children and adults.

Antihemophilic factor (human)

Alphanate

Antihemophilic factor (recombinant)

ReFacto

Treatment of von Willebrand's disease For the control and prevention of hemorrhagic episodes and for surgical prophylaxis in patients with hemophilia A (congenital factor VIII deficiency or classic hemophilia). Prophylaxis and treatment of bleeding in individuals with hemophilia A or for prophylaxis when surgery is required in individuals with hemophilia A.

Antihemophilic factor (recombinant)

Kogenate

Antihemophilic factor/von Willebrand factor complex (human), dried, pasteurized

Humate-P

Treatment of patients with von Willebrand's disease

anti-interferon-gamma Fab from goats Antimelanoma Antibody XMMME-001-DTPA 111 Indium

For the treatment of immunologic corneal allograft rejection Diagnostic use in imaging systemic and nodal

Antimelanoma Antibody XMMME-001-DTPA 111 Indium melanoma metastasis.

Antimelanoma Antibody XMMME-001-RTA

Antimelanoma Antibody resection. surgical XMMME-001-RTA

Treatment of stage III melanoma not amenable to

Antipyrine Test Antisense 20-mer oligonucleotide complementary to R2 component of ribonucleotide reductase mRNA antisense 20-mer phosphorothioate oligonucleotide [complementary to the coding region of R2 component of the human GTI-2040 ribonucleotide reductase mRNA]

For use as an index of hepatic drug-metabolizing capacity.

Treatment of acute myeloid leukemia

Treatment for renal cell carcinoma Treatment of homozygous familial hypercholesterolemia

Antisense inhibitor of apoB-100

Anti-tap-72 immunotoxin Anti-tenascin 81C6 monoclonal antibody labeled w/ I 131

Xomazyme-791 Treatment of metastatic colorectal adenocarcinoma.

Antithrombin III (human) Antithrombin III (human) Antithrombin III (human) concentrate IV

ATnativ Thrombate III Kybernin P

Treatment of primary malignant brain tumors For the treatment of patients with hereditary antithrombin III deficiency in connection with surgical or obstetrical procedures or when they suffer from thromboembolism. For replacement therapy in congenital deficiency of

AT-III for prevention and treatment of thrombosis and pulmonary emboli.

Antithrombin III human

For prophylaxis and treatment of thromboembolic episodes in patients with genetic AT-III deficiency. Preventing or arresting episodes of thrombosis in patients with congenital AT-III deficiency and/or to prevent the occurrence of thrombosis in patients with AT-III deficiency who have undergone trauma or who Antithrombin III human to undergo surgery or parturition. are about

Anti-thymocyte Globulin (Rabbitt) Anti-thymocyte serum Antivenin crotaline (pit-viper) equine immune F(ab)2)

Thymoglobulin Treatment of myelodysplastic syndrome (MDS)organ Treatment of allograft rejection, including solid Nashville Rabbit marrow transplantation. Anti-thymocyte Serum
(kidney, liver, heart, lung, and pancreas) and bone

Antivipmyn

Treatment of envenomation by Crotaline snakes

Antivenin, crotalidae polyvalent immune Fab (ovine) Antivenom (crotalidae) purified (avian) AP1903

CroFab

Treatment of envenomations inflicted by North American crotalid snakes. Treatment of envenomation by poisonous snakes belonging to the Crotalidae family. Treatment of acute graft-versus-host disease in patients undergoing bone marrow transplantation.

APL 400-020 V-Beta DNA vaccine Apomorphine Apomorphine

Treatment of cutaneous T cell lymphoma. For use as rescue treatment for early morning motor dysfunction in late-stage Parkinson's disease. Treatment of the on-off fluctuations associated with late-stage Parkinson's disease. Treatment of the on-off fluctuations associated with late-stage Parkinson's disease. For the treatment of patients in a vegetative state or minimally conscious state for up to 12 months following a severe traumatic brain injury (traumatic or spontaneous)

Apomorphine HCl

Apokyn

Apomorphine hydrochloride

Aprotinin Arcitumomab

Trasylol

For prophylactic use to reduce perioperative blood loss and the homologous blood transfusion requirement in patients undergoing cardiopulmonary bypass surgery in the course of repeat coronary artery bypass graft surgery, and in selected cases of primary c Diagnosis and localization of primary, residual,

99m Tc-labeled CEA-Scan metastatic medullary thyroid carcinoma. recurrent and

Arginine butyrate

Treatment of sickle cell disease and beta thalassemia.

Arginine butyrate

Treatment of beta-hemoglobinopathies and betathalassemia.

arimoclomol

Treatment of amyotrophic lateral sclerosis

Aripiprazole arsenic

Abilify Trisenox

Treatment of Tourette's syndrome Treatment of acute myelocytic leukemia subtypes M0, M1, M2, M4, M5, M6 and M7

Arsenic trioxide

Trisenox

Treatment of malignant glioma

arsenic trioxide

Trisenox

Treatment of chronic myeloid leukemia

Arsenic trioxide

Trisenox

Treatment of acute promyelocytic leukemia.

Arsenic trioxide

Trisenox

Treatment of multiple myeloma.

arsenic trioxide

Trisenox

Treatment of liver cancer

Arsenic trioxide

Trisenox

Treatment of chronic lymphocytic leukemia

arsenic trioxide artemether/lumefantrine

Trisenox Coartem

Treatment of myelodysplastic syndrome. For the treatment of infections due to Plasmodium falciparum or mixed infections including P. falciparum.

Artesunate

Immediate treatment of malaria

Artesunate

Treatment of malaria.

As-101

Treatment of acquired immunodeficiency syndrome.

Ascorbic acid

Ascor L 500

Treatment of scurvy

Atomoxetine hydrochloride

STRATTERA

Atovaquone

Mepron

Treatment of Tourette's Syndrome Prevention of Pneumocystis carinii pneumonia (PCP) in high-risk, HIV-infected patients defined by a history of one or more episodes of PCP and/or a peripheral CD4+ (T4 helper/inducer) lymphocyte count less than or equal to 200/mm3. Treatment of AIDS associated Pneumocystis Carinii Pneumonia.

Atovaquone

Mepron

Atovaquone

Mepron

Primary prophylaxis of HIV-infected persons at high risk for developing Toxoplasma gondii encephalitis. Treatment and suppression of Toxoplasma gondii encephalitis.

Atovaquone Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination with activated autologous blood derived T-cells

Mepron

Treatment of primary central nervous system malignancies

augmerosen

Genasense

Treatment of acute myelocytic leukemia

augmerosen

Genasense

Treatment of multiple myeloma

augmerosen autologous antigen presenting cells pulsed with autologous tumor Ig idiotype Autologous cultured endothelial cells on a donor human corneal disk Autologous dendritic cells pulsed with autologous antigens from primay malignant brain tumor cells Autologous DNP-conjugated tumor vaccine Autologous incubated macrophage Autologous or allogeneic limbal epithelial stem cells expanded ex vivo on human amniotic membrane autologous tumor-derived gp96 heat shock protein-peptide complex autologous tumor-derived gp96 heat shock protein-peptide complex

Genasense

Treatment of chronic lymphocytic leukemia

Mylovenge

Treatment of multiple myeloma Treatment of Fuch's dystrophy, pseudophakic bullous keratopathy, and bullous keratopathy

DCVax-Brain M-Vax

Treatment of therapy in melanoma patients with For adjuvant primary brain malignant cancer surgically resectable lymph node metastasis (Stage III and limited Stage IV disease). Therapy to improve the motor and sensory neurological outcome in acute cases of spinal cord injury Treatment of ocular surface diseases that are characterized by total limbal stem cell deficiency

Oncophage

Treatment of renal cell carcinoma

Oncophage

Treatment of metastatic melanoma

Autolymphocyte therapy

Treatment of renal cell carcinoma.

axitinib

For treatment of pancreatic cancer.

azacitidine

Vidaza

Treatament of myelodysplastic syndromes Treatment of oral manifestations of graft-versus-host disease. Inhalation therapy for control of gram-negative bacteria in the respiratory tract of patients with cystic fibrosis Treatment of stage IIb through IV metastatic melanoma

Azathioprine aztreonam

Imuran

Bacillus Calmette-Guerin vaccine

Bacitracin

Baclofen Baclofen

Treatment of antibiotic-associated pseudomembranous enterocolitis caused by toxins A Altracin and B elaborated by Clostridium difficile. Treatment of intractable spasticity caused by spinal cord injury, multiple sclerosis, and other spinal diseases (including spinal ischemia, spinal tumor, transverse myelitis, cervical spondylosis, and Lioresal Intrathecal degenerative myelopathy). Treatment of intractable spasticity due to multiple sclerosis or spinal cord injury.

Baclofen

Lioresal Intrathecal Treatment of spasticity associated with cerebral palsy.

baclofen

Treatment of dystonia

Balsalazide disodium

Colazal

Treatment of pediatric patients with ulcerative colitis Prophylaxis of solid organ rejection.

Basiliximab

Simulect

beclomethasone 17,21-dipropionate Beclomethasone dipropionate

Bec

Prevention of gastrointestinal graft-versus-host disease For oral administration in the treatment of intestinal graft-versus-host disease.

Bendamustine hydrochloride

Treanda

Benzoate and phenylacetate

Ucephan

Treatment of chronic lymphocytic leukemia For adjunctive therapy in the prevention and treatment of hyperammonemia in patients with urea cycle enzymopathy due to carbamylphosphate synthetase, ornithine, transcarbamylase, or argininosuccinate synthetase deficiency. Treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle. light induced skin For the prevention of visible photosensitivity as a result of porfimer sodium

benzoate/phenylacetate Benzophenone-3, octylmethoxycinnamate, avobenzone, titanium dioxide, zinc oxide Benzydamine hydrochloride Benzylpenicillin, benzylpenicilloic, benzylpenilloic acid

Ammonul

Total Block VL SPF 75 photodynamic therapy Tantum

Beractant

Prophylactic treatment of oral mucositis resulting from radiation therapy for head and neck cancer. Assessing the risk of administrating penicillin when it is the preferred drug of choice in adult patients who have previously received penicillin and have a history Pre-Pen/MDM of clinical sensitivity. Treatment of full-term newborn infants with respiratory failure caused by meconium aspiration syndrome, persistent pulmonary hypertension of the newborn, or Survanta Intratracheal Suspension pneumonia and sepsis.

Beractant

Survanta intratracheal suspension respiratory distress syndrome. Prevention of neonatal

Beractant Beraprost

Survanta intratracheal suspension respiratory distress syndrome. Treatment of neonatal arterial hypertension Treatment of pulmonary
associated with any New York Heart Association classification (Class I, II, III, or IV).

Beta alethine

Betathine

Treatment of metastatic melanoma.

Beta alethine

Betathine

Treatment of multiple myeloma.

Betaine

Cystadane

Treatment of homocystinuria. Prevention of recurrence of primary ventricular fibrillation.

Bethanidine sulfate

Bethanidine sulfate

Treatment of primary ventricular fibrillation.

Betulinic acid

Topical treatment of metastatic melanoma

Bevacizamub

Avastin

Treatment of malignant glioma

Bevacizumab

Avastin

Therapeutic treatment of patients with ovarian cancer

Bevacizumab

Avastin

Treatment of pancreatic cancer

Bevacizumab

Avastin

Treatment of renal cell carcinoma Treatment of cutaneous manifestations of cutaneous T-cell lymphoma in patients who are refractory to at least one prior systemic therapy.

Bexarotene

Targretin

bifidobacterium longum infantis 35624

Treatment of pediatric Crohn's disease

Bindarit Bioartificial liver system utilizing xenogenic hepatocytes in a hollow fiber bioreactor cartridge (BAL)

Treatment of lupus nephritis. Treatment of patients with acute liver failure presenting with encephalopathy deteriorating beyond Parson's grade 2 Use in the management of patients undergoing continuous renal replacement therapy with Normocarb HF hemofiltration For use as a graft for restoring a cornea-like epithelial phenotype to substitute for the normal corneal epithelium that is lost in patients due to total limbal stem cell deficiency

biocarbonate infusate

Bio-engineered oral mucosal tissue

Bis(4-fluorophenyl)phenylacetamide Bispecific molucule with two linked murine single-chain Fv regions directed against CD3 & CD19

Treatment of sickle cell disease. Treatment of indolent B-cell lymphoma, excluding CLL and NHL with CNS involvement For use as an anticoagulant in patients with or at risk of heparin-induced thrombocytopenia/heparin-induced thrombocytopenia thrombosis syndrome

bivalirudin

Angiomax

Bleomycin

Blenoxane

Treatment of pancreatic cancer.

Bleomycin sulfate

Blenoxane

Treatment of malignant pleural effusion.

BMY-45622

Treatment of ovarian cancer.

Bortezomib

Velcade

Treatment of multiple myeloma

Bosentan Botulinum toxin type A

Tracleer Dysport

Treatment of pulmonary arterial hypertension. Treatment of dynamic muscle contractures in pediatric cerebral palsy patients.

Botulinum toxin type A

Dysport

Treatment of spasmodic torticollis (cervical dystonia).

Botulinum toxin type A Botulinum toxin type A Botulinum toxin type A

Dysport Botox

Treatment of essential blepharospasm. Treatment of dynamic muscle contracture in pediatric cerebral palsy patients. Treatment of synkinetic closure of the eyelid associated with VII cranial nerve aberrant regeneration.

Botulinum toxin type A Botulinum toxin type A Botulinum toxin type A

Botox Botox Botox

Treatment of cervical dystonia. Treatment of strabismus associated with dystonia in adults (patients 12 years of age and above). Treatment of blepharospasm associated with dystonia in adults (patients 12 years of age and above).

Botulinum toxin type B

Myobloc

Treatment of cervical dystonia.

Botulinum toxin type F

Treatment of spasmodic torticollis (cervical dystonia).

Botulinum toxin type F

Treatment of essential blepharospasm.

Botulism immune globulin

BabyBIG

Treatment of infant botulism.

Bovine colostrum Bovine immunoglobulin concentrate, Cryptosporidium parvum

Treatment of AIDS-related diarrhea. Treatment and symptomatic relief of Cryptosporidium parvum infection of the gastrointestinal tract in Treatment of cryptosporidiosis immunocompromised patients. caused by the presence of Cryptosporidium parvum in the gastrointestinal tract of patients who are immunodeficient/immunocompromised or immunocompetent.

Sporidin-G

Bovine whey protein concentrate

Immuno-C

Branched chain amino acids

Treatment of amyotrophic lateral sclerosis.

Brimonidine

Alphagan

Treatment of anterior ischemic optic neuropathy.

Brivaracetam Bromhexine

Treatment of symtomatic myoclonus

Bisolvon

Treatment of mild to moderate keratoconjunctivitis sicca in patients with Sjogren's syndrome. Radiation sensitizer in the treatment of primary brain

Broxuridine bryostatin-1 Buffered intrathecal electrolyte/dextrose injection

Broxine/Neomark tumors.

For use in combination with paclitaxel in the treatment of esophageal cancer For use as a diluent in the intrathecal administration of methotrexate and cytarabine for the prevention or treatment meningeal leukemia and lymphocytic Elliotts B Solution lymphoma. For the treatment of pruritus in patients with Alagille Syndrome

Buffered Ursodeoxycholic Acid

Ursocarb

Buprenorphine hydrochloride

Subutex

Treatment of opiate addiction in opiate users.

Buprenorphine in combination with naloxone

Suboxone

Treatment of opiate addiction in opiate users. As preparative therapy in the treatment of malignancies with bone marrow transplantation. For use as preparative therapy for malignancies treated with bone marrow transplantation.

Busulfan Busulfan

Busulfex Spartaject

Busulfan busulfan

Spartajet-Busulfan Intrathecal therapy for neoplastic meningitis Partaject
Preparative therapy for pediatric patients undergoing bone marrow transplantation

Busulfan Buthionine sulfoxamine Buthionine sulfoxamine

Spartaject

Treatment children asbrain malignancies. For use in of primary a modulator of chemotherapy for the treatment of pediatric patients with neuroblastoma Use as a modulator of chemotherapy for the treatment of pediatric patients with primary malignant brain tumors

Butyrylcholinesterase Butyrylcholinesterase

Treatment of post-surgical apnea. For the reduction and clearance of toxic blood levels of cocaine encountered during a drug overdose.

BW 12C

Treatment of sickle cell disease.

C1 esterase inhibitor (human) C1 esterase inhibitor (human) C1-esterase-inhibitor, human, pasteurized C1-inhibitor

Treatment of angioedema Treatment and prevention of angioedema caused by C1-esterase inhibitor deficiency.

Berinert P

Prevention and/or treatment of acute attacks of hereditary angioedema. Prevention of acute attacks of angioedema, including short-term prophylaxis for patients requiring dental or

C1-inhibitor (human) vapor heated, Immuno other surgical procedures.

C1-inhibitor

C1-inhibitor (human) vapor heated, Immuno Treatment of acute attacks of angioedema.

cAC10-vcMMAE (4)

Treatment of Hodgkin's lymphoma.

Caffeine

Cafcit

Treatment of apnea of prematurity. Treatment of symptomatic Paget's disease (osteitis

Calcitonin salmon nasal spray

Miacalcin Nasal Spray deformans).

Calcitonin-human for injection

Cibacalcin

Treatment of symptomatic Paget's disease (osteitis deformans). Treatment of hyperphosphatemia in end stage renal failure. Treatment of hyperphosphatemia in end stage renal disease.

Calcium acetate

Phos-Lo

Calcium acetate Calcium carbonate

R & D calcium carbonate/600 stage renal disease.

Treatment of hyperphosphatemia in patients with end

Calcium gluconate Calcium gluconate gel Calcium gluconate gel 2.5%

Calgonate H-F Gel

For use as a wash for hydrofluoric acid spills on human skin. For use in the emergency topical treatment of hydrogen fluoride (hydrofluoric acid) burns. Emergency topical treatment of hydrogen fluoride (hydrofluoric acid) burns.

Calfactant

Infasurf

Acute respiratory distress syndrome (ARDS)

Capsaicin

Capsaicin

Treatment of postherpetic neuralgia. Treatment of intermetatarsal neuroma (Morton's Neuroma) that does not respond to conservative treatment and requires either neurectomy or neurolysis

capsaicin

Treatment of erythromelalgia

Capsaicin

Treatment of painful HIV-associated neuropathy Treatment of N-acetylglutamate synthetase deficiency. of persons with AIDS and in patients with Treatment

Carbamylglutamic acid Carbovir

symptomatic HIV infection and a CD4 count less than 200/mm3.

Carmustine

Treatment of intracranial malignancies. Treatment of oral drug overdosage to speed lower bowel evacuation.

Cascara sagrada fluid extract

Catumaxomab

Removab

Treatment of ovarian cancer

CD4 human truncated 369 AA polypeptide CD5-T lymphocyte immunotoxin

Soluble T4

Treatment of acquired immunodeficiency syndrome. Treatment of graft versus host disease and/or rejection in patients who have received bone marrow Xomazyme-H65 transplants.

CDP571

Treatment of Crohn's disease.

Ceftriaxone sodium

Rocephin

Cells produced using the AastromReplicelle System and SC-I Therapy Kit

Treatment of amyotrophic lateral sclerosis For use in patients receiving high dose chemotherapy who are unable to generate an acceptable dose of peripheral blood stem cells and who have a sufficient bone marrow aspirate without morphological evidence of tumor

Cenersen sodium

Treatment of acute myeloid leukemia Treatment of scorpion envenomations requiring medical attention.

Centruroides immune F(ab)2 Ceramide trihexosidase/alpha-galactosidase A

Alacramyn

Fabrazyme

Treatment of Fabry's disease. Prophylactic treatment of patients exposed to inhalation anthrax.

cethromycin

Cetiedil citrate injection

Treatment of sickle cell disease crisis.

cetuximab

Erbitux

Treatment of pancreatic cancer

Cetuximab

Erbitux

Treatment of squamous cell cancer of the head and neck in patients who express epidermal growth factor receptor.

Chenodeoxycholic acid

Chenofalk

Treatment of cerebrotendinous xanthomatosis

chenodeoxycholic acid

Chenodiol Chimeric (human-murine) G250 IgG monoclonal antibody chimeric (murine-human) IgG1 mAb against IL-6 Chimeric (murine-human) IgG1k monoclonal antibody against interleukin-6

Chenix

Treatment of cerebrotendinous xanthomatosis For patients with radiolucent stones in well opacifying gallbladders, in whom elective surgery would be undertaken except for the presence of increased surgical risk due to systemic disease or age.

Treatment of renal cell carcinoma.

Treatment of multiple myeloma

Treatment of Castleman's disease For treatment of shiga-toxin producing bacterial infection.

Chimeric monoclonal antibodies

Chimeric monoclonal antibody to mesothelin Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4 Chimeric, humanized monoclonal antibody to staphylococcus

Treatment of pancreatic cancer

Treatment of multiple sclerosis. Prophylaxis of Staphylococcus epidermidis sepsis in low birth weight (1500 grams or less) infants. For use in the amelioration of oral mucositis associated with cytoreductive therapy used in conditioning patients for bone marrow transplantation therapy. Treatment of inborn errors of cholesterol and bile acid synthesis and metabolism Treatment of choline deficiency, specifically the choline deficiency, hepatic steatosis, and cholestasis, associated with long-term parenteral nutrition. Prevention and/or treatment of choline deficiency in patients on long-term parenteral nutrition For use in correcting vesicoureteral reflux in the pediatric population.

Chlorhexidine gluconate mouthrinse cholic acid (3 alpha, 7 alpha, 12 alpha trihydroxy 5-beta cholanolic acid)

Peridex Falkochol

Choline chloride Choline chloride

Intrachol IntraChol

Chondrocyte-alginate gel suspension

Chondroitinase

Treatment of patients undergoing vitrectomy.

cilengitide

Treatment of malignant glioma

Ciliary neurotrophic factor Ciliary neurotrophic factor, recombinant human Ciliary neurotrophic factor, recombinant human

Treatment of amyotrophic lateral sclerosis. Treatment of motor neuron disease (including amyotrophic lateral sclerosis, progressive muscular atrophy, progressive bulbar palsy, and primary lateral sclerosis).

Treatment of spinal muscular atrophies.

cinacalcet cis-Amminedichloro(2methylpyridine)platinum(II)

Sensipar

Treatment of hypercalcemia in patients with parathyroid carcinoma

Treatment of small cell lung cancer. Treatment of osteogenic sarcoma metastatic to the

Cisplatin in liposomal formulation

SLIT Cisplatin for inhalation lung

Cisplatin/epinephrine

IntraDose

Treatment of metastatic malignant melanoma. Treatment of squamous cell carcinoma of the head and neck. Treatment of renal and bladder calculi of the apatite

Cisplatin/epinephrine Citric acid, glucono-delta-lactone and magnesium carbonate

IntraDose

Renacidin Irrigationstruvite variety. or

Civamide

Zucapsaicin

Treatment of postherpetic neuralgia of the trigeminal nerve

Cladribine

Leustatin

Treatment of acute myeloid leukemia.

Cladribine

Leustatin Injection Treatment of hairy cell leukemia.

Cladribine

Leustatin Injection Treatment of chronic lymphocytic leukemia.
Treatment of the chronic progressive form of multiple sclerosis.

Cladribine

Mylinax

Cladribine

Leustatin Injection Treatment of non-Hodgkin's lymphoma.
Treatment of cerebral vasospasm following subarachnoid hemorrhage Prevention of Pneumocystis carinii pneumonia in AIDS patients. Treatment of Pneumocystis carinii pneumonia associated with AIDS patients.

Clazosentan

Erajet

Clindamycin Clindamycin

Cleocin Cleocin

Clindamycin hydrochloride

Treatment of sarcoidosis

clofarabine

Clofarex

Treatment of acute myelogenous leukemia

clofarabine

Clolar

Treatment of acute lymphoblastic leukemia Treatment of lepromatous leprosy, including dapsoneresistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum.

Clofazimine

Lamprene

Clonazepam

Klonopin

Clonidine Clostridial collagenase

Duraclon

Treatment of hyperekplexia (startle disease). For continous epidural administration as adjunctive therapy with intraspinal opiates for the treatment of pain in cancer patients tolerant to, or unresponsive to, intraspinal opiates. Treatment of advanced (involutional or residual stage) Dupuytren's disease.

Clotrimazole

Topical treatment of children and adults with pouchitis

Clotrimazole

Treatment of Huntington's disease

Clotrimazole

Treatment of sickle cell disease.

c-myb antisense oligodeoxynucleotide Coagulation factor IX

Treatment of chronic myelogenous leukemia

Mononine

Replacement treatment and prophylaxis of the hemorrhagic complications of hemophilia B.

Coagulation Factor IX (human)

AlphaNine

For use as replacement therapy in patients with hemophilia B for the prevention and control of bleeding episodes, and during surgery to correct defective hemostasis.

Coagulation Factor IX (recombinant) Coagulation factor VIIa (recombinant)

BeneFix NovoSeven

Treatment of hemophilia B. Prevention of bleeding episodes in patients with acquired inhibitors to Factor VIII or Factor IX Prevention of bleeding episodes in Glanzmann's thrombasthenia Prevention of bleeding episodes in patients with congenital Factor VII deficiency Treatment of bleeding episodes in patients with acquired inhibitors to Factor VIII or Factor IX Prevention of bleeding episodes in patients with hemophilia A or B, with or without inhibitors Treatment of bleeding episodes in Glanzmann's thrombasthenia Treatment of bleeding episodes in patients with congenital factor VII deficiency Treatment of bleeding in patients experiencing intracranial hemorrhage. Treatment of bleeding episodes in hemophilia A or B patients with inhibitors to Factor VIII or Factor IX.

Coagulation factor VIIa (recombinant)

NovoSeven

Coagulation factor VIIa (recombinant) Coagulation Factor VIIa (Recombinant)

NovoSeven NovoSeven

Coagulation factor VIIa (recombinant)

NovoSeven

Coagulation factor VIIa (Recombinant) Coagulation factor VIIa (recombinant) Coagulation Factor VIIa (Recombinant) Coagulation factor VIIa (recombinant)

NovoSeven NovoSeven NovoSeven NovoSeven

cobiprostone

Treatment of cystic fibrosis

Coenzyme Q10

Treatment of Huntington's disease

colchicine

Treatment of familial Mediterranean fever

colchicine Colchicine Colfosceril palmitate, cetyl alcohol, tyloxapol Colfosceril palmitate, cetyl alcohol, tyloxapol

For the treatment of Behcet's Syndrome. For arresting the progression of neurologic disability caused by chronic progressive multiple sclerosis.

Exosurf Neonatal for Intratracheal Suspensiondisease, also known at all gestational ages. Prevention of hyaline membrane Exosurf Neonatal for Intratracheal less. weeks gestation or Suspension

Treatment of established hyaline membrane disease

as respiratory distress syndrome, in infants born at 32

Colfosceril palmitate, cetyl alcohol, tyloxapol

Exosurf

Treatment of adult respiratory distress syndrome.

Collagenase (lyophilized) for injection

Plaquase

Treatment of Peyronie's disease.

Combretastatin A4 phosphate Combretastatin A4 Phosphate

Treatment of ovarian cancer Treatment of anaplastic thyroid cancer, medullary thyroid cancer, and stage IV papillary or follicular thyroid cancer

conjugate of human transferrin and a mutant diphtheria toxin (CRM 107)

TransMID

Treatment of malignant tumors of the central nervous system Treatment of steatorrhea in patients with short bowel syndrome Intrathecal treatment of neuropathic pain associated with spinal cord injury

conjugated bile acids Contulakin-G

COBARTin

Cordycepin Corticorelin ovine triflutate

Acthrel

Treatment differentiating pituitarylymphocytic leukemia For use in of TdT-positive acute and ectopic production of ACTH in patients with ACTH-dependent Cushings syndrome.

Corticotropin-releasing factor, human

Xerecept

Treatment of peritumoral brain edema.

Coumarin

Onkolox

Treatment of renal cell carcinoma. Treatment of stage II (T4), stage III, and stage IV melanoma

Coxsackievirus A21

Cavatak

Creatine

Creapure

Treatment of Huntington's disease

creatine

Creapure

Treatment of amyotrophic lateral sclerosis

Cromolyn sodium

Gastrocrom

Treatment of mastocytosis.

Cromolyn sodium 4% ophthalmic solution Cryptosporidium hyperimmune bovine colostrum IgG concentrate cultured, partially T-Cell depleted, allogenic thymic tissue for transplantation CY-1503

Opticrom 4% ophthalmic solution keratoconjunctivitis. Treatment of vernal
Treatment of diarrhea in AIDS patients caused by infection with for primary immune deficiency resulting As a therapy Cryptosporidium parvum. from athymia associated with complete DiGeorge Syndrome Treatment of neonates and infants undergoing cardiopulmonary bypass during surgical repair of congenital heart lesions.

Cylexin

CY-1503 CY-1899 Cyclo {{(E,Z)-(2S,3R,4R)-3-hydroxy-4-methyl2-(methylamino)nona-6,8-dienoyl}-L-2aminobytyrl-N-methyl-glycyl-N-methyl-Lleucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-Dalanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-Nmethyl-L-valyl}

Cylexin

Treatment of post-ischemic pulmonary reperfusion edema following surgical treatment for chronic thromboembolic pulmonary hypertension. Treatment of chronic active hepatitis B infection in HLA-A2 positive patients.

Treatment and chronic control of non-infectious posterior, intermediate and pan-uveitis

cyclosporin

Prophylaxis of organ rejection in patients receiving allogeneic lung transplant Treatment of amyotrophic lateral sclerosis and its variants Treatment of acute rejection in patients requiring allogenic lung transplants.

Cyclosporin A cyclosporine

Cyclosporin Pluminiq

Cyclosporine 2% ophthalmic ointment Cyclosporine 2% ophthalmic ointment

Treatment of patients at high risk of graft rejection following penetrating keratoplasty. For use in corneal melting syndromes of known or presumed immunologic etiopathogenesis, including Mooren's ulcer.

cyclosporine A

Treatment of vernal keratoconjunctivitis For the prevention of acute rejection in cornea transplant patients

Cyclosporine A implant Cyclosporine in combination with omega-3 polyunsaturated fatty acids Cyclosporine ophthalmic

Prevention of solid organ graft rejection.

Optimmune

Treatment of severe keratoconjunctivitis sicca associated with Sjogren's syndrome.

Cyproterone acetate

Androcur

Treatment of severe hirsutism.

Cysteamine

Treatment of nephropathic cystinosis.

Cysteamine Cysteamine hydrochloride

Cystagon

Treatment of nephropathic cystinosis. Treatment of corneal cystine crystal accumulation in cystinosis patients.

Cystic fibrosis gene therapy Cystic fibrosis Tr gene therapy (recombinant adenovirus) Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator gene

Treatment of cystic fibrosis.

AdGVCFTR.10 Treatmentfibrosis transmembrane conductance For cystic of cystic fibrosis.

regulator protein replacement therapy in cystic fibrosis patients.

Treatment of cystic fibrosis.

Cytarabine liposomal

DepoCyt

Treatment of neoplastic meningitis.

cytarabine liposome Cytomegalovirus DNA Vaccine w/Copolymer/Benzalkonium Chloride Cytomegalovirus DNA vaccine with plasmids expressing pp65 and gB genes

DepoCyt

Treatment of gliomas For use in prevention of clinically significant CMV viremia, CMV disease and associated complications in at-risk hematopoietic cell transplant and solid organ transplant populations Prevention of clinically significant cytomegalovirus (CMV) viremia, CMV disease and asociated complications in at-risk hematopoietic cell transplant and solid transplant populations

Cytomegalovirus immune globulin (human) Cytomegalovirus immune globulin intravenous (human)

CytoGam

Prevention or attenuation of primary cytomegalovirus disease in immunosuppressed recipients of organ transplants. For use in conjunction with ganciclovir sodium for the treatment of cytomegalovirus pneumonia in bone marrow transplant patients.

Daclizumab

Zenapax

Prevention of acute renal allograft rejection.

Dantrolene sodium Dapsone Dapsone USP

Dantrium

Treatment of the neuroleptic malignant syndrome. Prophylaxis of toxoplasmosis in severely immunocompromised patients with CD4 counts below 100. For the combination treatment of Pneumocystis carinii pneumonia in conjunction with trimethoprim.

Dapsone

Dapsone USP

Dapsone

Prophylaxis for Pneumocystis carinii pneumonia. Treatment of Philadelphia-positive acute lymphoblastic leukemia

Dasatinib

Sprycel

Dasatinib Daunorubicin citrate liposome injection

Sprycel DaunoXome

Treatment of chronic myelogenous leukemia Treatment of patients with advanced HIV-associated Kaposi's sarcoma.

DEAE-rebeccamycin

Treatment of bile duct tumors Debridement of acute, deep dermal burns in hospitalized patients

debrase

Debridase

Decitabine

Dacogen

Treatment of acute myeloid leukemia

decitabine

Treatment of sickle cell anemia

Decitabine

Treatment of chronic myelogenous leukemia.

Decitabine Deferasirox deferiprone

Dacogen Exjade Ferriprox

Treatment of myelodysplastic syndromes. Treatment of chronic iron overload in patients with transfusion-dependent anemias Treatment of iron overload in patients with hematologic disorders requiring chronic transfusion therapy

deferoxamine-starch conjugate

Treatment of acute iron poisoning.

defibrotide

For the prevention of hepatic veno-occlusive disease.

Defibrotide

For the treatment of hepatic veno-occlusive disease

Defibrotide Dehydroepiandrosterone

Treatment of thrombotic thrombocytopenic purpura. Treatment of systemic lupus erythematosus (SLE) and the reduction in the use of steroids in steroiddependent SLE patients. Replacement therapy in individuals with adrenal insufficiency

Dehydroepiandrosterone (DHEA)

Fidelin

Dehydroepiandrosterone sulfate sodium

Treatment of serious burns requiring hospitalization. To accelerate the re-epithelialization of donor sites in those hospitalized burn patients who must undergo autologous skin grafting. Treatment of patients with Cutaneous T-cell Lymphoma.

Dehydroepiandrosterone sulfate sodium

Denileukin diftitox Deslorelin

Ontak Somagard

Desmoglein 3 synthetic peptide (PI-0824)

Treatment of pemphigus vulgaris Treatment of mild hemophilia A and von Willebrand's disease.

Desmopressin acetate Dexamethasone dexanabinol

Posurdex

For use in posterior segment drug delivery system in the treatment of idiopathic intermediate uveitis. For the attenuation or amelioration of the long-term neurological sequelae associated with moderate and severe traumatic brain injury Treatment of anthracycline extravasation during chemotherapy For the prevention of cardiomyopathy associated with doxorubicin administration.

dexrazoxane

Totect

Dexrazoxane

Zinecard

dextran 1 Dextran 70

Treatment of cystic fibrosis

Dehydrex

Treatment of recurrent corneal erosion unresponsive to conventional therapy.

Dextran and deferoxamine

Bio-Rescue

Treatment of acute iron poisoning. For use as an adjunct to the treatment of cystic fibrosis.

Dextran sulfate (inhaled, aerosolized)

Uendex

Dextran sulfate sodium

Treatment of aquired immunodeficiency syndrome.

DHA-paclitaxel

Taxoprexin

Treatment of pancreatic cancer Treatment of adenocarcinoma of the stomach or lower esophagus

DHA-paclitaxel

Taxoprexin

DHA-paclitaxel

Taxoprexin

Treatment of metastatic malignant melanoma

For use as a nutritional supplement for the treatment Dianeal peritoneal dialysis solution with 1.1% of malnourishment in patients undergoing continuous Nutrineal (Peritoneal Dialysis Solution with 1.1% Amino Acid amino acids ambulatory peritoneal dialysis. For the management of selected, refractory, patients with epilepsy, on stable regimens of antiepileptic drugs (AEDs), who require intermittent use of Diazepam viscous solution for rectal diazepam to control bouts of increased seizure administration activity. Diaziquone Treatment of primary brain malignancies (grade III and IV astrocytomas).

Dideoxyinosine

Treatment of acquired immunodeficiency syndrome.

Diethyldithiocarbamate

Imuthiol

Treatment of AIDS. For treatment of patients with known or suspected internal contamination with plutonium, americium or curium to increase the rates of elimination. Treatment of patients with known or suspected internal contamination with plutonium, americium, or curium to increase the rates of elimination.

diethylenetriaminepentaacetate (DPTA)

Diethylenetriaminepentaacetic acid (DTPA)

Diethylnorspermine (DENSPM)

Treatment for hepatocellular carcinoma

diferuloylmethane

Treatment of cystic fibrosis

Digitoxin

Treatment of cystic fibrosis

digitoxin

Treatment of soft tissue sarcomas

digitoxin Digoxin immune FAB (Ovine)

Digibind

Digoxin immune fab(ovine)

Digidote

Treatment of ovarian cancer Treatment of potentially life threatening digitalis intoxication in patients who are refractory to management by conventional therapy. Treatment of life-threatening acute cardiac glycoside intoxication manifested by conduction disorders, ectopic ventricular activity and (in some cases) hyperkalemia. Treatment of uncomplicated malaria caused by "Plasmodium falciparum," Plasmodium vivax," Plasmodium malariae," or "Plasmodium ovale." Treatment of weight loss in AIDS patients with HIVTreatment of increased intracranial pressure in patients with severe, closed-head injury, also known as traumatic brain coma, for whom no other effective treatment is available. Treatment of cutaneous manifestations of scleroderma. Treatment of palmar-plantar erythrodysethesia syndrome. Topical treatment for the prevention of soft tissue injury following extravastion of cytotoxic drugs.

dihydroartemisinin and piperaquine Dihydrotestosterone

Eurartesim

Androgel -DHT associated wasting.

Dimethyl sulfoxide

Dimethyl sulfoxide

Dimethylsulfoxide Dimethylsulfoxide

Dipalmitoylphosphatidylcholine /phosphatidylglycerol diphenylcyclopenone Disaccharide tripeptide glycerol dipalmitoyl

ALEC

Prevention and treatment of neonatal respiratory distress syndrome. Treatment of chronic severe forms of alopecia areata (Alopecia Totalis [AT]/Alopecia Universalis [AU])

Immther

Treatment of pulmonary and hepatic metastases in patients with colorectal adenocarcinoma.

Disodium clodronate

Treatment of hypercalcemia of malignancy. Treatment of increased bone resorption due to malignancy. Treatment of hepatic intoxication by Amanita phalloides (mushroom poisoning). Therapeutic management of patients with lung disease attributable to cystic fibrosis.

Disodium clodronate tetrahydrate Disodium silibinin dihemisuccinate DMP 777 DNA plasmid vector expressing human IL-12 gene DNA-lipid complex (DMRIE/DOPE)/plasmid vector (VCL-1102, Vical) expressing human interleukin-2

Bonefos Legalon

Treatment of ovarian cancer.

Leuvectin

Treatment of renal cell carcinoma.

DNP-Modified autologous tumor vaccine

O-Vax

Adjuvant therapy for the treatment of ovarian cancer

docosahexanoic acid-paclitaxel

Taxoprexin

Treatment of hormone-refractory prostate cancer. Treatment of bronchopulmonary infection in patients with cystic fibrosis who are colonized with Pseudomonas aeruginosa or Burkholderia cepacia. To reduce mucous viscosity and enable the clearance of airway secretions in patients with cystic fibrosis.

Doripenem

Dornase alfa

Pulmozyme

Dovitinib

Treatment of multiple myeloma

Doxorubicin HCL liposome injection Doxorubicin HCl with pluronic L-61 and pluronic F-127

Doxil

Treatment of multiple myeloma

Treatment of esophageal carcinoma

Doxorubicin liposome

Doxil

Treatment of ovarian cancer.

doxorubicin PIHCA nanoparticles

Doxorubicin Transdrug Treatment of hepatocellular carcinoma

D-peptide of the sequence AKRHHGYKRKFH PulmaDex - NH2 Dronabinol

Marinol

Treatment of cystic of appetite and prevention of For the stimulation fibrosis weight loss in patients with a confirmed diagnosis of AIDS.

Droxidopa

Treatment of neurogenic symptomatic orthostatic hypotension in patients with primary autonomic failure, dopamine-beta-hydroxylase deficiency, and nondiabetic autonomic neuropathy.

Duramycin Dynamine

Treatment of cystic fibrosis. Treatment of hereditary motor and sensory neuropathy type I (Charcot-Marie-Tooth disease).

Dynamine

Treatment of Lambert Eaton myasthenic syndrome.

eculizumab

Idiopathic membranous glomerular nephropathy

eculizumab Edotreotide Efaproxiral

Soliris OctreoTher

Treatment of paroxysmal nocturnal hemoglobinuria Treatment of somatostatin receptor-positive neuroendocrine gastroenteropancreatic tumors Adjunct to whole brain radiation therapy for the treatment of brain metastases in patients with breast cancer

Eflornithine

Treatment of anaplastic glioma Treatment of Pneumocystis carinii pneumonia in AIDS patients. Treatment of Trypanosoma brucei gambiense infection (sleeping sickness).

Eflornithine HCl Eflornithine HCl

Ornidyl Ornidyl

Elcatonin

Intrathecal treatment of intractable pain.

Enadoline hydrochloride Encapsulated porcine islet preparation

Treatment of severe head injury.

BetaRx

Treatment of type I diabetic patients who are already on immunosuppression.

Eniluracil Enisoprost Enisoprost

Treatment of hepatocellular carcinoma For use in organ transplant patients to diminish the nephrotoxicity induced by cyclosporine. For use with cyclosporine in organ transplant recipients to reduce acute transplant rejection.

Enteric-coated cysteamine

Treatment of cystinosis

Enzastaurin Epidermal growth factor (human) Epidermal growth factor (human)

Treatment of glioblastoma multiformeregeneration and For acceleration of corneal epithelial the healing of stromal tissue in the condition of nonhealing corneal defects. For promotion of cutaneous wound healing in extreme burn treatment protocols.

Epirubicin

Ellence

Treatment of breast cancer.

Epoetin alfa

Epogen

Treatment of anemia associated with HIV infection or HIV treatment. Treatment of anemia associated with end stage renal disease.

Epoetin alfa

Epogen

Epoetin alfa

Treatment of myelodysplastic syndrome. Treatment of anemia associated with end stage renal disease.

Epoetin alpha

Procrit

Epoetin alpha Epoetin alpha

Procrit Procrit

Treatment of anemia of prematurity in preterm infants. Treatment of HIV associated anemia related to HIV infection or HIV treatment. Treatment of anemia associated with end stage renal disease.

Epoetin beta

Marogen

Epoprostenol

Flolan

Treatment of secondary pulmonary hypertension due to intrinsic precapillary pulmonary vascular disease.

Epoprostenol Epoprostenol Epoprostenol

Flolan Flolan Cycloprostin

Treatment of primary pulmonary hypertension. Replacement of heparin in patients requiring hemodialysis and who are at increased risk of hemorrhage. of heparin in patients requiring Replacement hemodialysis and who are at increased risk of hemorrhage.

epratuzumab

LymphoCIDE

Treatment of non-Hodgkin's lymphoma.

Eprodisate Epstein Barr Virus specific cytotoxic T lymphocytes

Fibrillex

Treatment of secondary amyloidosis Prevention and treatment of EBV-post transplant lymphoproliferative disease after hematopoietic stem cell transplant or solid organ transplant.

Erlotinib Hydrochloride

Tarceva

Treatment of malignant gliomas

Erwinia L-asparaginase

Erwinase

Erwinia L-asparaginase

Treatment of acute lymphocytic leukemia. For use as an alternative to E. coli asparaginase in those situations where repeat courses of asparaginase therapy for acute lymphoblastic leukemia are required or where allergic reactions force the discontinuance of the E. coli preparation. Treatment of anemia associated with end stage renal disease. Treatment of anemia associated with end stage renal disease.

Erythropoietin (human, recombinant)

Erythropoietin (recombinant human)

Estradiol Gel

EstroGel

Etanercept

Enbrel

Estrogen replacement therapy in females with Turner Reduction syndrome in signs and symptoms of moderately to severely active polyarticular-course juvenile rheumatoid arthritis in patients who have had an inadequate response to one or more diseasemodifying anti-rheumatic drugs.

Ethanol gel

Treatment of congenital lymphatic malformations

Ethanol gel Ethanolamine oleate

Treatment of congenital venous malformations

Ethamolin

Treatment of patients with esophageal varices that have recently bled, to prevent rebleeding.

Ethinyl Estradiol, USP Ethiofos

Treatment of Turner's syndrome. Use as a chemoprotective agent for cisplatin and cyclophosphamide in the treatment of ovarian cancer.

Ethyl eicosapentaenoate

Treatment of Huntington's disease. Prevention of degenerative metabolic bone disease occurring in patients who require long term (6 months Didronel IV infusion or greater) total parenteral nutrition. Treatment of degenerative metabolic bone disease occurring in patients who require long term (6 months Didronel IV Infusion or greater) of hypercalcemia of malignancy Treatment total parenteral nutrition.

Etidronate disodium

Etidronate disodium Etidronate disodium

Didronel

inadequately managed by dietary modification and/or oral hydration.

Etiocholanedione

Treatment of Prader-Willi syndrome.

Etiocholanedione Ex vivo cultured adult human mesenchymal stem cells Exemestane Exisulind Factor XIII [A2] homodimer, recombinant DNA origin Factor XIII [A2} homodimer, recombinant DNA origin

Treatment of aplastic anemia.

Prochymal Aromasin

Treatment of acute graftbreast cancer in Treatment of advanced versus host disease postmenopausal women whose disease has progressed following tamoxifen therapy. For the suppression and control of colonic adenomatous polyps in the inherited disease adenomatous polyposis coli.

Treatment of congenital FXIII deficiency For the prophylaxis of bleeding associated with congential FXIII deficiency

factor XIII concentrate (human), pasteurized

Fibrogammin P Treatment of congenital factor XIII deficiency.

Factor XIII, recombinant

Treatment of congenital factor XIII deficiency.

Fampridine

Neurelan

Treatment of chronic, incomplete spinal cord injury.

Fampridine

Neurelan

Relief of symptoms of multiple sclerosis.

Felbamate

Felbatol

Treatment of Lennox-Gastaut syndrome.

Fenobam hydrochloride

Treatment of fragile X syndrome

fenretinide

Treatment of Ewing's sarcoma family of tumors.

Fenretinide ferric hexacyanoferrate (II) "Prussian Blue"

Treatment of neuroblastoma Treatment of patients with known or suspected internal contamination with radioactive or nonradioactive cesium or thallium

FIAU Fibrinogen (human)

Adjunctive treatment of chronic active hepatitis B. For the control of bleeding and prophylactic treatment of patients deficient in fibrinogen. Treatment of non-healing corneal ulcers or epithelial defects which have been unresponsive to conventional therapy and the underlying cause has been eliminated. Treatment of non-healing corneal ulcers or epithelial defects which are unresponsive to conventional therapy and for which any infectious cause of the defect has been eliminated.

Fibronectin (human plasma derived)

Fibronectin (plasma derived)

Filgrastim

Neupogen

Treatment of patients with severe chronic neutropenia (absolute neutrophil count less than 500/mm3).

Filgrastim

Neupogen

Treatment of myelodysplastic syndrome. Treatment of neutropenia associated with bone marrow transplants. Reduction in the duration of neutropenia, fever, antibiotic use, and hospitalization, following induction and consolidation treatment for acute myeloid leukemia. of patients with AIDS who, in addition, are Treatment afflicted with cytomegalovirus retinitis and are being treated with ganciclovir. For use in the mobilization of peripheral blood progenitor cells for collection in patients who will receive myeloablative or myelosuppressive chemotherapy.

Filgrastim

Neupogen

Filgrastim Filgrastim

Neupogen Neupogen

Filgrastim

Neupogen

Floxuridine, FUDR Fludarabine phosphate Fludarabine phosphate Flumecinol

Intraperitoneal treatment of gastric cancer.

Fludara Fludara Zixoryn

Treatment of chronic lymphocytic leukemia (CLL), including refractory CLL. Treatment and management of patients with nonHodgkins lymphoma. Treatment of hyperbilirubinemia in newborn infants unresponsive to phototherapy.

Flunarizine

Sibelium

Treatment of alternating hemiplegia.

Fluocinolone Fluorouracil Fluorouracil Fluorouracil

Retisert Adrucil

Treatment uveitis involving the posterior segment of the eye. For use in combination with leucovorin for therapy of metastatic combination with interferon alpha-2a, For use in adenocarcinoma of the colon and rectum.

recombinant, for the treatment of esophageal carcinoma. For use in combination with interferon alpha-2a, recombinant, for the treatment of advanced colorectal carcinoma.

Fluorouracil

Treatment of glioblastoma multiforme. Treatment of body dysmorphic disorder in children and adolescents

Fluoxetine

Prozac

Fluoxetine

Prozac

Treatment of autism. For the initiation and re-initiation of spermatogenesis in adult males with reproductive failure due to hypothalamic or pituitary dysfunction, hypogonadotropic hypogonadism. AMENDED indication 6/27/00: For the induction of spermatogenesis in men with pr

Follitropin alfa, recombinant

Gonal-F

Fomepizole

Antizole

Treatment of methanol or ethylene glycol poisoning.

Fomepizole

Antizole

Treatment of methanol or ethylene glycol poisoning.

Fosphenytoin Fructose-1,6-diphosphate Fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1

Cerebyx Cordox

For the acute treatment of patients with status epilepticus of the grand mal type. Treatment of painful vaso-occlusive episodes associated with sickle cell disease. Treatment of X-linked hypohidrotic ectodermal dysplasia

G17DT Immunogen

Treatment of gastric cancer

G17DT Immunogen

Treatment of adenocarcinoma of the pancreas

Gabapentin

Neurontin

Treatment of amyotrophic lateral sclerosis.

Gallium nitrate injection Gamma hydroxybutyrate Gamma-hydroxybutyric acid

Ganite

Treatment of hypercalcemia of malignancy. Treatment of narcolepsy and the auxiliary symptoms of cataplexy, sleep paralysis, hypnagogic hallucinationsnarcolepsy and behavior. Treatment of and automatic the auxiliary symptoms of cataplexy, sleep paralysis, hypnagogic hallucinations, and automatic behavior.

Gammalinolenic acid

Treatment of juvenile rheumatoid arthritis.

Ganaxolone

Treatment of infantile spasms. Treatment of acute herpetic keratitis (dendritic and geographic ulcers)

Ganciclovir

Virgan

Ganciclovir intravitreal implant Ganciclovir sodium Gancyclovir

Vitrasert Implant Treatment of cytomegalovirus retinitis. Cytovene
Treatment of cytomegalovirus retinitis in immunocompromised patients with AIDS. Treatment of severe human cytomegalovirus

infections in specific immunosuppressed patient populations.

Gangliosides as sodium salts

Cronassial

Treatment of retinitis pigmentosa.

Gavilimomab

Acute graft-versus-host disease (aGVHD)

Gemtuzumab zogamicin Gene plasmid hVEGF165 driven by human cytomegalovirus, and [2,3bis(oleoyl)propyl]trimethyl ammonium and dioleoyl phosphatidyl ethanolamine genetically engineered herpes simplex virus (G207)

Mylotarg

Treatment of CD33-positive acute myeloid leukemia. Prevention of complications due to neointimal hyperplasia disease in certain vascular anastomoses.

Trinam

Tretament of malignant glioma

Geneticin Gentamicin impregnated PMMA beads on surgical wire Gentamicin liposome injection

Treatment of amoebiasis.

Septopal Maitec

Treatment of chronic osteomyelitis of post-traumatic, postoperative, or hematogenous origin. Treatment of disseminated Mycobacterium aviumintracellulare infection.

Glatiramer acetate

Copaxone

Treatment of multiple sclerosis.

Glatiramer acetate for injection

Copaxone

Treatment of primary-progressive multiple sclerosis

glucarpidase

Voraxaze

Glutamine Glyceol

NutreStore

Treatment of patients at risk of methotrexate toxicity For use with human growth hormone in the treatment of short bowel syndrome (nutrient malabsorption from the gastrointestinal tract resulting from an inadequate absorptive surface). To decrease intracranial hypertension and/or alleviate cerebral edema in patients who may benefit from osmotherapy.

Glyceryl tri (4-phenylbutyrate)

Treatment of spinal muscular atrophy

Glyceryl trioleate and glyceryl trierucate Glycopyrrolate

Treatment of adrenoleukodystrophy. Treatment of pathologic (chronic moderate to severe) drooling in pediatric patients

Golimumab

Gonadorelin acetate

Lutrepulse

Treatment of chronic sarcoidosis For induction of ovulation in women with hypothalamic amenorrhea due to a deficiency or absence in the quantity or pulse pattern of endogenous GnRH secretion.

Gossypol

Treatment of cancer of the adrenal cortex.

Gp100 adenoviral gene therapy Granulocyte macrophage-colony stimulating factor Granulocyte macrophage-colony stimulating factor Granulocyte macrophage-colony stimulating factor Granulocyte macrophage-colony stimulating factor Granulocyte macrophage-colony stimulating factor Group B streptococcus immune globulin Growth hormone releasing factor Guanethidine monosulfate

Treatment of metastatic melanoma.

Leucomax Leucomax

Treatment of severe thermal injuries in patients with greater than 40% full or partial thickness burns. Treatment of chronic lymphocytic leukemia to increase granulocyte count.

Leucomax

Treatment of myelodysplastic syndrome. Treatment of neutropenia associated with bone marrow transplants.

Leucomax

Leucomax

Treatment of neutropenia due to hairy cell leukemia. Treatment of neonates for disseminated group B streptococcal infection. For the long-term treatment of children who have

growth failure due to a lack of adequate endogenous growth hormone secretion.

Ismelin

Treatment of moderate to severe reflex sympathetic dystrophy and causalgia.

Guanfacine

Tenex

Treatment of fragile X syndrome.

Gusperimus

Spanidin

Treatment of acute renal graft rejection episodes.

h5G1.1-mAb

Treatment of dermatomyositis Treatment of mild to moderate acute malaria caused by susceptible strains of P. falciparum and P. vivax.

Halofantrine

Halfan

Halofuginone heat killed Mycobacterium w immunomodulator heat killed mycobacterium w immunomodulator

Stenorol

Treatment of systemic sclerosis.

CADI Mw CADI Mw

Active tuberculosis Adjuvant to multi-drug therapy in the management of multibacillary leprosy

Heme arginate

Normosang

Treatment of symptomatic stage of acute porphyria.

Heme arginate

Normosang

Treatment of myelodysplastic syndromes.

Hemin

Panhematin

Amelioration of recurrent attacks of acute intermittent porphyria (AIP) temporarily related to the menstrual cycle in susceptible women and similar symptoms which occur in other patients with AIP, porphyria variegata and hereditary coproporphyria.

Hemin and zinc mesoporphyrin

Hemex

Treatment of acute porphyric syndromes.

Heparin

Treatment of cystic fibrosis

Heparin sodium Heparin-binding epidermal growth factor-like growth factor Hepatitis B immune globulin intravenous (human)

Treatment of cystic fibrosis Prevention and treatment of necrotizing enterocolitis (NEC) in preterm infants with birth weight less than 1,500 grams

Nabi-HB

Prophylaxis against hepatitis B virus reinfection in liver transplant patients. Prophylaxis of hepatitis C infection in liver transplant recipients. For the prevention of hepatitis B virus (HBV) reinfection in patients who have received a liver transplantation

Hepatitis C virus immune globulin (human) HepeX-B

Herpes simplex virus gene Histamine Histamine

Treatment of primary and metastatic brain tumors.

Maxamine Ceplene

For use as an adjunct to cytokine therapy in the treatment of malignant melanoma. Adjunct to cytokine therapy in the treatment of acute myeloid leukemia.

Histrelin Histrelin

Supprelin LA

Treatment of central precocious puberty Treatment of acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria.

Histrelin acetate

Supprelin Injection Treatment of central precocious puberty.

HIV neutralizing antibodies HLA-B7/Beta2M DNA Lipid (DMRIE/DOPE) Complex

Immupath Allovectin-7

Treatment of acquired immunodeficiency syndrome. Treatment of invasive and metastatic melanoma (Stages II, III, and IV).

homoharringtonine

Treatment for chronic myelogenous leukemia

HPA-23

Treatment of acquired immunodeficiency syndrome. Treatment of recurrent respiratory papillomatosis (RRP) For use in the treatment of 1D10+ B cell nonHodgkin's lymphoma

Hsp E7

Hu1D10, humanized monoclonal antibody Human acid precursor alpha-glucosidase, recombinant

Remitogen

Treatment of glycogen storage disease type II.

Human alpha 2,6 sialyltransferase adenoviral gene therapy

Treatment of patients with invasive (malignant) brain and central nervous system tumors lacking alpha 2,6 sialyltransferase.

Human anti-CD30 monoclonal antibody

Treatment of Hodgkin's disease

human anti-CD4 monoclonal antibody Human anti-integrin receptor av monoclonal antibody human anti-integrin receptor avb3/avb5 monoclonal antibody human anti-transforming growth factor beta 1 monoclonal antibody

HuMax-CD4

Treatment of mycosis fungoides

Treatment of patients with angiosarcoma Treatment of patients with high-risk stage II, stage III, and stage IV malignant melanoma

Treatment of systemic sclerosis

human anti-transforming growth factor-B1,2,3 Human cytomegalovirus immunoglobulin

human gammaglobulin

Treatment of idiopathic pulmonary fibrosis(CMV) Prevention of congenital cytomegalovirus infection following primary CMV infection in pregnant women Treatment of gastrointestinal disturbances (to include constipation, diarrhea, and abdominal pain) associated with regression-onset autism in pediatric patients.

human gammaglobulin

Treatment of idiopathic inflammatory myopathies

human gammaglobulin Human IgM monoclonal antibody (C-58) To CMV Human IgM monoclonal antibody (C-58) To CMV

Treatment for juvenile rheumatoid arthritis

Centovir Centovir

Prophylaxis of cytomegalovirus infections in bone marrow transplant patients. Treatment of cytomegalovirus infections in allogenic bone marrow transplant patients.

Human immune globulin Human immunodeficiency virus immune globulin Human immunodeficiency virus immune globulin Human immunodeficiency virus immune globulin Human immunoglobin anti-CD30 monoclonal antibody Human immunoglobulin (IgG1k)antiCTLA-4 monoclonal antibody human leukocyte-derived cytokine mixture Human monoclonal antibody against plateletderived growth factor D

Xepol

Treatment of post-polio syndrome

Treatment of AIDS. Treatment of HIV-infected pregnant women and infants of HIV-infected mothers.

Hivig

Treatment of HIV-infected pediatric patients.

Treatment of CD30+ T-cell lymphoma Treatment of high risk Stage II, Stage III, and Stage IV melanoma For neoadjuvant therapy in pts. w/squamous cell carcinoma of the head and neck To slow the progression of IgA nephropathy and delay kidney failure in patients affected by the disease. Treatment of hospital acquired pneumonia caused by serotype 011 positive Pseudomonas aeruginosa

Human monoclonal antibody directed against Aerumab 11 serotype 011 Pseudomonas aeruginosa

Human monoclonal antibody targeting CCchemokine ligand 2 Human plasma coagulation Factor VIII and human plasma von Willebrand Factor Human telomerase reverse transcriptase peptide vaccine Human T-lymphotropic virus type III Gp160 antigens

Wilate

Treatment of pancreatic cancer Treatment of von Willebrand disease except for surgical and/or invasive procedures in patients with von Willebrand disease in whom desmopressin is either ineffective or contraindicated

Treatment of pancreatic cancer

Vaxsyn HIV-1

Treatment of AIDS.

Human umbilical tissue-derived cells

Treatment of retinitis pigmentosa

Humanized anti-CD3 monoclonal antibody humanized anti-human CD16 monoclonal antibody

Treatment of recent-onset Type I diabetes Treatment of adult idiopathic thrombocytopenic purpura For the induction of donor-specific immunologic unresponsiveness resulting in prophylaxis of organ rejection without the need for chronic immunosuppressive therapy, in patients receiving allogeneic renal transplants. Prevention of acute graft-vs-host disease following bone marrow transplantation.

Humanized anti-human CD2 MAb Humanized anti-tac

MEDI-507 Zenapax

Humanized MAb (IDEC-131) to CD40L humanized monoclonal antibody against Shiga-like toxin II Humanized monoclonal antibody to the high affinity folate alpha receptor hyaluronic acid

Treatment of systemic lupus erythematosus. To prevent the development of or to decrease the incidence and severity of hemolytic uremic syndrome and associated sequelae of Shiga-like toxinproducing E. coli.

Treatment of ovarian cancer Treatment of emphysema in patients due to alpha-1 antitrypsin deficiency Treatment of severe intrapartum hypertension (diastolic blood pressure greater than or equal to 110 or systolic blood pressure greater than or equal to 160) associated with severe preeclampsia/eclampsia of pregnancy

Hydralazine

Hydroxocobalamin

Cyanokit

Treatment of acute cyanide poisoning

Hydroxocobalamin

Treatment of acute cyanide poisoning

Hydroxycobalamin/sodium thiosulfate

Treatment of severe acute cyanide poisoning.

hydroxyurea

Treatment of pediatric patients with sickle cell anemia.

Hydroxyurea

Droxia

Treatment of patients with sickle cell anemia as shown by the presence of hemoglobin S.

Hypericin

Treatment of glioblastoma multiforme.

Hypericin

Treatment of cutaneous T-cell lymphoma.

I(131)-TM-601 (chlorotoxin)

treatment of malignant glioma

Iboctadekin

Treatment of renal cell carcinoma

ibritumomab tiuxetan

Zevalin

Treatment of B-cell non-Hodgkin's lymphoma.

Ibuprofen i.v. solution

Salprofen

Prevention of patent ductus arteriosus.

Ibuprofen lysine

NeoProfen

Treatment of patent ductus arteriosus.

Icatibant

Treatment of angioedema Treatment of burn patients hospitalized with burninduced edema

Icatibant acetate

Icodextrin 7.5% with Electrolytes Peritoneal Dialysis Solution

Extraneal (with 7.5% Icodextrin) Peritoneal Dialysis Solutio disease and requiring peritoneal dialysis treatment.

Treatment of those patients having end stage renal

Idarubicin

Idamycin

Treatment of chronic myelogenous leukemia.

Idarubicin Idarubicin HCl for injection

Idamycin Idamycin

Treatment of myelodysplastic syndromes. Treatment of acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia. Treatment of acute lymphoblastic leukemia in pediatric patients.

Idarubicin HCl for injection

Idamycin

idebenone

Treatment of Leber's hereditary optic neuropathy.

idebenone

Treatment of Duchenne muscular dystrophy Treatment of cardiomyopathy associated with Friedreich's ataxia

Idebenone

Idoxuridine

Treatment of nonparenchymatous sarcomas.

idursulfase

Elaprase

Long term enzyme replacement therapy for patients with mucopolysaccharidosis II (Hunter Syndrome)

Ifosfamide

Ifex

Treatment of testicular cancer.

Ifosfamide

Ifex

Treatment of bone sarcomas

Ifosfamide

Ifex

Treatment of soft tissue sarcomas.

IL13-PE38QQR IL-4 Pseudomonas Toxin Fusion Protein (IL4(38-37)-PE38KDEL)

Treatment of malignant glioma

Treatment of astrocytic glioma.

Iloprost inhalation solution

Ventavis

Treatment of pulmonary arterial hypertension Treatment of Raynaud's phenomenon secondary to systemic sclerosis.

Iloprost solution for infusion

Iloprost solution for infusion

Treatment of heparin-associated thrombocytopenia.

Imatinib

Gleevec

Treatment of chronic myelogenous leukemia Treatment of systemic mastocytosis without the D816V c-kit mutation Treatment of myeloproliferative disorders/myelodysplastic syndromes associated with platelet-derived growth factor gene re-arrangements

Imatinib mesylate

Gleevec

Imatinib mesylate

Gleevec

Imatinib mesylate

Gleevec

Treatment of idiopathic hypereosinophilic syndrome including acute and chronic eosinophilic leukemia Treatment of Philadelphia-positive acute lymphoblastic leukemia

imatinib mesylate

Gleevec

imatinib mesylate

Gleevec

Treatment of dermatofibrosarcoma protuberans

imatinib mesylate Imciromab pentetate

Gleevec Myoscint

Treatment of gastrointestinal stromal tumors Detecting early necrosis as an indication of rejection of orthotopic cardiac transplants.

imexon

Amplimexon

Treatment of ovarian cancer.

Imexon

Treatment of multiple myeloma.

Imexon

Treatment of pancreatic adenocarcinoma

Imexon Imiglucerase Immortalized human liver cells found in the extracorporeal liver assist device

Treatment of metastatic malignant melanoma

Cerezyme

Replacement therapy in patients with types I, II, and III Gaucher's disease. Treatment of fulminant hepatic failure (acute liver failure) Treatment of chronic inflammatory demyelinating polyneuropathy

ELAD

Immune Globulin (Human) Immune Globulin (Human) containing high titers of West Nile virus antibodies

Gamunex

Omr-IgG-am (tm) 5% (WNV) West Nile virus infection Treatment of the

Immune Globulin Intravenous (human)

Carimune NF

Treatment for Guillain Barre Syndrome

Immune globulin intravenous (human)

Gammagard Liquid Treatment of multifocal motor neuropathy

Immune globulin intravenous (human)

Immune GlobulinTreatment of patients with acute myocarditis. Intravenous (human) Immuno, Iveegam

Immune globulin intravenous (human)

Iveegam, Immunoreatment of polymyositis/dermatomyositis. T

Immune globulin intravenous (human)

Iveegam, Immunoreatment of juvenile rheumatoid arthritis. T

Immune globulin intravenous, human

Immune Globulin Subcutaneous (Human)

Infection prophylaxis in pediatric patients affected with the human immunodeficiency virus. Treatment of patients with primary immune deficiency (PID) that are intolerant to immune globulin intravenous (IGIV) due to severe adverse events or Vivaglobin P (proposed) poor venous access

Gamimune N

Implitapide

Imported fire ant venom, allergenic extract

Treatment of homozygous familial hypercholesterolemia For skin testing of victims of fire ant stings to confirm fire ant sensitivity and if positive, for use as immunotherapy for the prevention of IgE-mediated anaphylactic reactions.

Inalimarev and falimarev Indium In 111 murine monoclonal antibody FAB to myosin Indium In-111 altumomab pentetate

Treatment of adenocarcinoma of the pancreas

Myoscint Hybri-ceaker

To aid in the diagnosis of myocarditis. Detection of suspected and previously unidentified tumor foci of recurrent colorectal carcinoma.

Indium-111 pentetreotide

NeuroendoMedix Treatment of neuroendocrine tumors

infliximab

Remicade

Treatment of juvenile rheumatoid arthritis

infliximab

Remicade

Treatment of giant cell arteritis Treatment of pediatric (0 to 16 years of age) ulcerative colitis

Infliximab

REMICADE

Infliximab

REMICADE

Treatment of pediatric (0 to 16 years of age) Crohn's Disease

Infliximab

Remicade

Treatment of chronic sarcoidosis Treatment of moderately to severely active Crohn's disease for the reduction of the signs and symptoms, in patients who have an inadequate response to conventional therapy; and treatment of patients with fistulizing Crohn's disease for the reduction in th

Infliximab

Remicade

INGN 201 INH-A00021

ADVEXIN Veronate

Treatment (prevention) of nosocomial bacteremia Reduction of head and neck cancer caused by staphylococci in very low birth weight infants.

inolimomab

Leukotac

Treatment of graft versus host disease

Inosine pranobex

Isoprinosine

Treatment of subacute sclerosing panencephalitis.

Interferon alfa-2a

Roferon A

Treatment of chronic myelogenous leukemia.

Interferon alfa-2a (recombinant) Interferon alfa-2a (recombinant) Interferon alfa-2a (recombinant)

Roferon-A Roferon-A Roferon-A

Treatment of renal cell carcinoma. For the treatment of metastatic malignant melanoma in combination with Teceleukin. For the concomitant administration with Teceleukin for the treatment of metastatic renal cell carcinoma.

Interferon alfa-2a (recombinant) Interferon alfa-2a (recombinant) Interferon alfa-2a (recombinant)

Roferon-A Roferon-A Roferon-A

Treatment of AIDS related Kaposi's sarcoma. For the concomitant administration with fluorouracil for the treatment of advanced colorectal cancer. For use in combination with fluorouracil for the treatment of esophageal carcinoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of AIDS-related Kaposi's sarcoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of acute hepatitis B.

Interferon alfa-2b (recombinant)

Intron A

Treatment of primary malignant brain tumors.

Interferon alfa-2b (recombinant)

Intron A

Treatment of carcinoma in situ of the urinary bladder.

Interferon alfa-2b (recombinant)

Intron A

Treatment of invasive carcinoma of the cervix.

Interferon alfa-2b (recombinant)

Intron A

Treatment of ovarian carcinoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of chronic myelogenous leukemia.

Interferon alfa-2b (recombinant)

Intron A

Treatment of metastatic renal cell carcinoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of laryngeal (respiratory) papillomatosis.

Interferon alfa-2b (recombinant) Interferon alfa-nl

Intron A Wellferon

Treatment of chronic papillomavirus in patients with Treatment of human delta hepatitis. severe resistant/recurrent respiratory (laryngeal) papillomatosis.

Interferon alfa-nl

Wellferon

Treatment of AIDS related Kaposi's sarcoma. For the systemic treatment of metastatic renal cell carcinoma. For the intralesional and/or systemic treatment of AIDS-related Kaposi's sarcoma. For the systemic treatment of cutaneous T-cell lymphoma.

Interferon beta (recombinant) Interferon beta (recombinant)

R-IFN-beta r-HuIFN-beta

Interferon beta (recombinant)

r-HuIFN-beta

Interferon beta, recombinant human

Betaseron

Treatment of acquired immunodeficiency syndrome. Treatment of patients with secondary progressive multiple sclerosis.

Interferon beta-1a

Rebif

Interferon beta-1a

Avonex

Treatment of multiple sclerosis.

Interferon beta-1a (recombinant human)

Treatment of acute non-A, non-B hepatitis. For the systemic treatment of cutaneous malignant melanoma. Treatment of symptomatic patients with AIDS including all patients with CD4 T-cell counts less than 200 cells per mm3.

Interferon beta-1a (recombinant) Interferon beta-1a (recombinant)

r-HuIFN-beta Rebif

Interferon beta-1b

Betaseron

Treatment of multiple sclerosis.

Interferon gamma 1-b Interferon gamma-1b

Actimmune Actimmune

Treatment of chronic granulomatous disease. Delaying time to disease progression in patients with severe, malignant osteopetrosis.

Interferon gamma-1b

Actimmune

Treatment of renal cell carcinoma.

Interferon-alfa-1b

Treatment of multiple myeloma

Interleukin-1 alpha, human recombinant Interleukin-1 alpha, human recombinant Interleukin-1 receptor antagonist, human recombinant Interleukin-1 receptor antagonist, human recombinant Interleukin-1 Trap

For hematopoietic potentiation in aplastic anemia. For the promotion of early engraftment in bone marrow transplantation.

Antril Antril

Treatment of juvenile rheumatoid arthritis. Prevention and treatment of graft versus host disease in transplant recipients. Treatment of Still's disease including juvenile rheumatoid arthritis and adult-onset Still's disease

Interleukin-1Trap Interleukin-2

Treatment of CIAS1-Associated Periodic Syndromes

Teceleukin

In combination with interferon alfa-2a for the treatment of metastatic malignant melanoma.

Interleukin-2

Teleleukin

Treatment of metastatic malignant melanoma.

Interleukin-2 Interleukin-2 Interleukin-3 human (recombinant)

Teceleukin Teceleukin

Treatment of metastatic renal cell carcinoma. In combination with interferon alfa-2a for the treatment of metastatic renal cell carcinoma. Promotion of erythropoiesis in Diamond-Blackfan anemia (congenital pure red cell aplasia). For sequential administration with sargramostim to accelerate neutrophil and platelet recovery in patients undergoing autologous bone marrow transplantation for the treatment of Hodgkin's disease or nonHodgkin's lymphoma.

Interleukin-3, human, recombinant Intraoral fluoride releasing system

IFRS

Prevention of dental caries due to radiation-induced xerostomia in patients with head and neck cancer

Intravenous immune globulin

VitiGam

Treatment of Stage IIB to IV malignant melanoma

Iobenguane I 123

For the diagnosis of pheochromocytoma.

Iobenguane I 123

For the diagnosis of neuroblastomas.

iobenguane I 131

Treatment of neuroendocrine tumors

Iobenguane I 131

Ultratrace

Treatment of neuroendocrine tumors For use as a diagnostic adjunct in patients with pheochromocytoma.

Iobenguane Sulfate I 131 Iobenguane Sulfate I-123

OmaClear

For scintigraphic detection, localization and staging of neuroblastoma. For the detection, localization, and staging of pheochromocytomas.

iobenguane sulfate I-123

OmaClear

Iodine 131 6B-iodomethyl-19-norcholesterol Iodine I 123 murine monoclonal antibody to alpha-fetoprotein Iodine I 123 murine monoclonal antibody to alpha-fetoprotein Iodine I 123 murine monoclonal antibody to hCG Iodine I 131 bis(indiumdiethylenetriaminepentaacetic acid)tyrosyllysine/hMN-14 x m734 F(ab')2 bispecific monoclonal antibody

For use in adrenal cortical imaging. Detection of alpha-fetoprotein producing germ cell tumors. Detection of hepatocellular carcinoma and hepatoblastoma. Detection of hCG producing tumors such as germ cell and trophoblastic cell tumors.

Pentacea

Treatment of small-cell lung cancer.

Iodine I 131 Lym-1 Monoclonal Antibody Iodine I 131 murine monoclonal antibody IgG2a to B cell Iodine I 131 murine monoclonal antibody to alpha-fetoprotein Iodine I 131 murine monoclonal antibody to alpha-fetoprotein Iodine I 131 murine monoclonal antibody to hCG Iodine I-131 radiolabeled chimeric MAb tumor 131IchTNT-1 necrosis treatment (TNT-1B)

Treatment of B-cell lymphoma.

Immurait, Ll-2-I-131 Treatment of B-cell leukemia and B-cell lymphoma.
Treatment of alpha-fetoprotein producing germ cell tumors. Treatment of hepatocellular carcinoma and hepatoblastoma. Treatment of hCG producing tumors such as germ cell and trophoblastic cell tumors. Treatment of glioblastoma multiforme and anaplastic astrocytoma.

irofulven

Treatment of renal cell carcinoma.

irofulven

Treatment of ovarian cancer. Treatment of patients with known or suspected internal contamination with radioactive or nonradioactive cesium or thallium

iron(III)-hexacyanoferrate(II)

Radiogardase

Isobutyramide Isobutyramide

Treatment of sickle cell disease and beta thalassemia.

Isobutyramide oral solution syndromes. thalassemia

Treatment of beta-hemoglobinopathies and beta-

Isofagomine tartrate Japanese encephalitis vaccine (live, attenuated) Ketoconazole

Treatment of Gaucher disease

Nizoral

Prevention ofcyclosporine A to diminish the For use with Japanese encephalitis. nephrotoxicity induced by cyclosporine in organ transplantation.

L-2-oxothiazolidine-4-carboxylic acid

Procysteine

Treatment of adult respiratory distress syndrome.

L-2-oxothiazolidine-4-carboxylic acid

Procysteine

Treatment of amyotrophic lateral sclerosis.

L-5-hydroxytryptophan Lactic acid lactic acid bacteria (Lactobacilli, Bifidobacteria, and Steptococci) lactic acid bacteria (Lactobacilli, Bifidobacteria, and Streptococcus species) Lactobin L-aminocarnityl-succinyl-leucyl-argininaldiethylacetal

Treatment of tetrahydrobiopterin deficiency.

Aphthaid

Treatment of severe aphthous stomatitis in severely, terminally immunocompromised patients.

Treatment of active chronic pouchitis Prevention of disease relapse in patients with chronic pouchitis

Lactobin

Treatment of AIDS-associated diarrhea unresponsive to initial antidiarrheal therapy. Treatment of Duchenne and Becker muscular dystrophy

Lamotrigine

Lamictal

Treatment of Lennox-Gastaut syndrome.

Lanreotide

Somatuline Depot Treatment for acromegly

laronidase

Aldurazyme

Treatment of patients with mucopolysaccharidosis-I.

Latrodectus immune F(ab)2

Aracmyn

Treatment of black widow spider envenomations Treatment of intractable spasticity in children with cerebral palsy. Treatment of intractable spasticity associated with spinal cord injury or multiple sclerosis.

L-Baclofen L-baclofen

Neuralgon Neuralgon

L-Baclofen

Treatment of trigeminal neuralgia.

L-baclofen

Treatment of trigeminal neuralgia.

L-cycloserine L-cysteine Leflunomide

Treatment of Gaucher's disease. For the prevention and lessening of photosensitivity in erythropoietic protoporphyria. Prevention of acute and chronic rejection in patients who have received solid organ transplants.

lenalidomide

Revlimid

Treatment of myelodysplastic syndromes

lenalidomide

Revlimid

Treatment of chronic lymphocytic leukemia.

lenalidomide

Revlimid

Treatment for multiple myeloma

Lentiviral vector encoded with a human betaglobin gene plasmid

Thalagen

Treatment of beta-thalassemia major and betathalassemia intermedia Treatment of heparin-associated thrombocytopenia type II.

Lepirudin

Refluden

Lestaurtinib Leucovorin Leucovorin Leucovorin calcium leukocyte interlukin

Treatment of acute myeloid leukemia

Leucovorin calcium treatment of metastatic colorectal cancer. Leucovorin calcium treatment of osteosarcoma. in the Wellcovorin Multikine

For use in combination with 5-fluorouracil for the For rescue use after high dose methotrexate therapy For use in combination with 5-fluorouracil for the treatment of metastatic colorectal cancer. Neoadjuvant therapy in patients with Squamous Cell Carcinoma of the Head and Neck For use as an adjunct to microsurgical peripheral nerve repair.

Leupeptin

Leuprolide acetate Levocabastine HCl ophthalmic suspension 0.05% Levocarnitine Levocarnitine Levocarnitine Levocarnitine

Lupron Injection Treatment of central precocious puberty.

Carnitor Carnitor Carnitor Carnitor

Treatment of vernal keratoconjunctivitis. Treatment of manifestations of carnitine deficiency in patients with end stage renal disease who require dialysis. Treatment of manifestations of carnitine deficiency in patients with end stage renal disease who require dialysis. For the treatment of secondary carnitine deficiency in valproic acid toxicity. For the prevention of secondary carnitine deficiency in valproic acid toxicity. Treatment of zidovudine-induced mitochondrial myopathy.

Levocarnitine

Carnitor

Levocarnitine

Carnitor

Treatment of pediatric cardiomyopathy. Treatment of primary and secondary carnitine deficiency of genetic origin.

Levocarnitine

Carnitor

Levocarnitine

Carnitor

Treatment of genetic carnitine deficiency.

Levodopa and carbidopa

Duodopa

Treatment of late stage Parkinson's disease.

Levomethadyl acetate hydrochloride

Orlaam

Treatment of heroin addicts suitable for maintenance on opiate agonists.

L-glutamine

Treatment of sickle cell disease

L-glutamyl-L-tryptophan

Treatment of AIDS-related Kaposi's sarcoma.

liarozole Lidocaine patch 5%

The treatment of congenital ichthyosis

Lidoderm Patch chronic pain in postherpetic neuralgia.

For relief of allodynia (painful hypersensitivity), and

Lintuzumab

Treatment of myelodysplastic syndrome.

lintuzumab

Treatment of acute myeloid leukemia.

lintuzumab

Zamyl

Treatment of acute myelogenous leukemia

Liothyronine sodium injection

Triostat

Treatment of myxedema coma/precoma.

Lipid/DNA human cystic fibrosis gene

Treatment of cystic fibrosis.

Liposomal amphotericin B

AmBisome

Treatment of histoplasmosis.

Liposomal amphotericin B

AmBisome

Treatment of visceral leishmaniasis.

Liposomal amphotericin B

AmBisome

Treatment of cryptococcal meningitis.

Liposomal annamycin

Treatment of acute myeloid leukemia

Liposomal annamycin

Treatment of acute lymphoblastic leukemia

Liposomal ciprofloxacin

For the management of bronchiectasis

Liposomal ciprofloxacin for inhalation

Management of cystic fibrosis

Liposomal cisplatin

LipOva-Pt

Treatment of ovarian cancer For aerosolized administration in the prevention and treatment of lung allograft rejection and pulmonary rejection events associated with bone marrow transplantation.

Liposomal cyclosporin A

Cyclospire

Liposomal doxorubicin hydrochloride Liposomal N-Acetylglucosminyl-NAcetylmuramly-L-Ala-D-isoGln-L-Ala -gylcerolidpalmitoyl Liposomal N-Acetylglucosminyl-NAcetylmuramly-L-Ala-D-isoGln-L-Ala -gylcerolidpalmitoyl

Sarcodoxome

Treatment of soft tissue sarcomas

ImmTher

Treatment of osteosarcoma.

ImmTher

Treatment of Ewing's sarcoma.

Liposomal nystatin liposomal p-ethoxy growth receptor bound protein-2 antisense product

Nyotran

Treatment of invasive fungal infections.

Treatment of chronic myelogenous leukemia

Liposomal prostaglandin E1 injection Liposomal-cis-bis-neodecanoato-trans-R,R1,2-diaminocyclohexane-Pt (II) Liposome encapsulated recombinant interleukin-2 Liposome encapsulated recombinant interleukin-2 Lisofylline

Treatment of acute respiratory distress syndrome.

Aroplatin

Treatment of malignant mesothelioma.

Treatment of brain and CNS tumors.

Treatment of cancers of the kidney and renal pelvis. Treatment of patients undergoing induction therapy for acute myeloid leukemia. For use in combination chemotherapy with the approved agent 5-fluorouracil in the palliative treatment of metastatic adenocarcinoma of the colon and rectum. For use in conjunction with high-dose methotrexate in the treatment of osteosarcoma.

L-leucovorin L-leucovorin

Isovorin Isovorin

Lodoxamide tromethamine

Alomide Ophthalmic Solutionvernal keratoconjunctivitis. Treatment of

Loxoribine

Treatment of common variable immunodeficiency. Treatment of spasticity associated with familial spastic paraparesis.

L-threonine

L-threonine

Threostat

Treatment of amyotrophic lateral sclerosis. Treatment of neuropathic pain associated with spinal cord injury

L-threonyl-L-prolyl-L-prolyl-L-threonine

L-tyrosine-L-serine-L-leucine

CMS-024

Treatment of hepatocellular carcinoma. Prevention of bronchopulmonary dysplasia in premature infants Treatment of bronchopulmonary dysplasia in premature infants. Treatment of meconium aspiration syndrome in newborn infants Treatment of acute respiratory distress syndrome in adults. Treatment of respiratory distress syndrome in premature infants.

Lucinactant

Surfaxin

Lucinactant

Surfaxin

Lucinactant

Surfaxin

Lucinactant

Surfaxin

Lucinactant

Surfaxin

Lysine acetylsalicylate injectable

Mafenide acetate solution

Treatment of pain and fever secondary to sickle cell disease crisis. For use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn Sulfamylon solution wounds.

Mafosfamide Mammalian target of rapamcyin (mTOR) inhibitor

Treatment of neoplastic meningitis

Treatment of soft tissue sarcoma For use to facilitate clearance of mucus in patients with bronchiectasis and in patients with cystic fibrosis at risk for bronchiectasis Treatment of high-risk Stage II, Stage III, and Stage IV melanoma Prevention of cytomegalovirus viremia and disease in the populations at risk.

Mannitol

Bronchitol

mannopentaose phosphate sulfate maribavir

Marijuana

Treatment of HIV-associated wasting syndrome.

Matrix metalloproteinase inhibitor

Galardin

Treatment of corneal ulcers.

MaxAdFVIII

Treatment of Hemophilia A

Mazindol

Sanorex

Treatment of Duchenne muscular dystrophy.

Mecamylamine

Inversine

Treatment of Tourette's syndrome.

Mecasermin

Myotrophin

Treatment of amyotrophic lateral sclerosis.

Mecasermin

Increlex

Treatment of growth hormone insensitivity syndrome.

mecasermin rinfabate

iPLEX

Treatment of growth hormone insensitivity syndrome (GHIS)

meclorethamine or nitrogen mustard

Treatment of mycosis fungoides.

MEDI-522

Vitaxin

For the treatment of metastatic melanoma

Medroxyprogesterone acetate

Hematrol

Treatment of immune thrombocytopenic purpura. Prevention of chloroquine-resistant Falciparum malaria.

Mefloquine HCl

Mephaquin

Mefloquine HCl Mefloquine HCl Mefloquine HCl

Mephaquin Lariam Lariam

Treatment of chloroquine-resistant Falciparummalaria. Prophylaxis of Plasmodium falciparum malaria which is resistant to other available drugs. Treatment of acute malaria due to Plasmodium falciparum and Plasmodium vivax. Treatment of patients with anorexia, cachexia, or significant weight loss (=/>10% of baseline body weight) and confirmed diagnosis of AIDS. Treatment of stage IIIb through IV metastatic melanoma

Megestrol acetate

Megace

Melanoma autologous dendritic cell vaccine

Melanoma cell vaccine Melanoma peptide vaccine

Canvaxin

Treatment of invasive melanoma. Treatment of HLA-A2+ patients with stage IIB, IIC, III, and IV malignant melanoma

Melanoma vaccine Melatonin Melatonin

Melacine Circadin

Treatment of stage III - IV melanoma. Treatment of non-24-hour sleep-wake disorder in blind individuals without light perception Treatment of circadian rhythm sleep disorders in blind people with no light perception.

meloxicam Melphalan Melphalan

Mobic

Treatment of juvenile rheumatoid arthritis For use in hyperthermic regional limb perfusion to Treatment of patients with multiple myeloma for whom

Alkeran for Injection metastatic melanoma of the extremity. treat Alkeran For Injectiontherapy is inappropriate. oral

mepivacaine

Treatment of postherpetic neuralgia

Mepivacaine

Treatment of painful HIV-associated neuropathy For first-line treatment in patients with hypereosinophilic syndrome Management of acute pulmonary exacerbations, in

mepolizumab Meropenem Mesna Mesna

Merrem IV

cystic fibrosis patients, due to respiratory tract infection with susceptible organisms. Inhibition of the urotoxic effects induced by oxazaphosphorine compounds such as cyclophosphamide.

Mesnex

For use as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis.

Methionine/L-methionine

Treatment of AIDS myelopathy.

Methotrexate

Rheumatrex

Treatment of juvenile rheumatoid arthritis.

Methotrexate sodium

Methotrexate

Treatment of osteogenic sarcoma.

Methotrexate with laurocapram

Methotrexate/azone Topical treatment of mycosis fungoides.

Methoxsalen

Uvadex

For use in conjunction with the UVAR photopheresis system to treat graft versus host disease. Treatment of metabolic disorders secondary to lipodystrophy leptin deficiency secondary to Treatment of generalized lipodystrophy and partial familial lipodystrophy

metreleptin metreleptin

Metronidazole Metronidazole (topical)

Metrogel Flagyl

Treatment of perioral dermatitis. Treatment of grade III and IV, anaerobically infected, decubitus ulcers.

Metronidazole (topical)

Metrogel

Treatment of acne rosacea.

Mibefradil Microbubble contrast agent Microvesiculated modified glycosylated tissue factor

Treatment of ovarian cancer

Filmix Neurosonographic Contrast Agent of intracranial tumors.

Intraoperative aid in the identification and localization Treatment of non-life threatening, mild to severe bleeding episodes due to cutaneous injuries or dental procedures in hemophiliac patients Treatment of bouts of increased seizure activity in selected refractory patients with epilepsy who are on stable regimens of anti-epileptic drugs and who require intermittent use of midazolam

Midazolam HCl

Midodrine HCl

Amatine

Treatment of patients with symptomatic orthostatic hypotension.

mifamuritide Mifepristone mifepristone

Junovan

Treatment of osteosarcoma Treatment of Cushing's syndrome secondary to ectopic ACTH secretion

Corlux

Treatment of the clinical manifestations of endogenous Cushing's symdrome.

miglustat

Zavesca

Treatment of Gaucher disease.

miltefosine

Impavido

Treatment of leishmaniasis.

Minocycline HCl

Minocin Intravenous Treatment of chronic malignant pleural effusion.

Minocycline hydrochloride

Treatment of sarcoidosis Treatment of intrauterine fetal death not accompanied by complete expulsion of the products of conception in the seconddiffuse non-Hodgkin's lymphoma, Treatment of and third trimesters of pregnancy. including AIDS-related diffuse non-Hodgkin's lymphoma.

misoprostol Mitoguazone

GyMiso apep

Mitolactol

Treatment of invasive carcinoma of the uterine cervix

Mitolactol Mitomycin-C

As adjuvant therapy in the treatment of primary brain tumors. Treatment of refractory glaucoma as an adjunct to ab externo glaucoma surgery.

Mitoxantrone

Novantrone

Treatment of hormone refractory prostate cancer.

Mitoxantrone

Novantrone

Treatment of secondary-progressive multiple sclerosis.

Mitoxantrone Mitoxantrone HCl MN14 monoclonal antibody to carcinoembryonic antigen MN14 monoclonal antibody to carcinoembryonic antigen

Novantrone Novantrone

Treatment of progressive-relapsing multiple sclerosis. Treatment of acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia.

Cea-Cide

Treatment of small cell lung cancer

Cea-Cide

Treatment of pancreatic cancer. Treatment of excessive daytime sleepiness in narcolepsy. Treatment of AIDS patients with neutropenia due to the disease, AZTor ganciclovir.

Modafinil Molgramostim

Provigil Leucomax

Molgramostim

Leucomax

Treatment of aplastic anemia.

monarsen Monoclonal Ab(murine) anti-idiotype melanoma-associated antigen Monoclonal antibodies (murine or human) to B-cell lymphoma

Treatment of Myasthenia Gravis

Melimmune

Treatment of invasive cutaneous melanoma.

Treatment of B-cell lymphoma.

Monoclonal antibody 17-1a Monoclonal antibody for immunization against lupus nephritis Monoclonal antibody to cytomegalovirus (human) Monoclonal antibody to cytomegalovirus (human) Monoclonal antibody to hepatitis B virus (human)

Panorex

Treatment of pancreatic cancer.

Treatment of lupus nephritis. Treatment of cytomegalovirus retinitis in patients with AIDS. Prophylaxis of cytomegalovirus disease in patients undergoing solid organ transplantation. patients Prophylaxis of hepatitis B reinfection in undergoing liver transplantation secondary to endstage chronic hepatitis B infection.

Monoclonal antibody-B43.13

Ovarex MAb-B43.13 Treatment of epithelial ovarian cancer.

Monoclonal antiendotoxin antibody XMMEn0e5

Treatment of patients with gram-negative sepsis which has progressed to shock.

Monolaurin Monooctanoin Morphine sulfate concentrate (preservative free) motexafin gadolinium

Glylorin Moctanin

Treatment of congenital primary ichthyosis. For dissolution of cholesterol gallstones retained in the common bile duct. For use in microinfusion devices for intraspinal administration in the treatment of intractable chronic pain. in conjunction with whole brain radiation for For use the treatment of brain metastases arising from solid tumors

Infumorph Xcytrin

MTC-DOX for Injection Mucoid exopolysaccharide Pseudomonas hyperimmune globulin Mucoid exopolysaccharide Pseudomonas hyperimmune globulin

MEP IGIV MEP IGIV

Treatment of hepatocellular carcinoma Treatment of pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis. Prevention of pulmonary infections due to

Multi-ligand somatostatin analogue Multi-vitamin infusion (neonatal formula)

Pseudomonas aeruginosa in patients with cystic fibrosis. Treatment of patients with functional gastroenteropancreatic (GEP) neuroendocrine tumors (specifically, carcinoid, insulinoma, gastrinoma, somastatinoma, GRFoma, VIPoma and glucagonoma. For establishment and maintenance of total parenteral nutrition in very low birth weight infants. Prevention of vitamin deficiency and thromboembolic complications in people receiving home parenteral nutrition and warfarin-type anticoagulant therapy

multi-vitiam infusion without vitamin K Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma Murine MAb to polymorphic epithelial mucin, human milk fat globule 1

M.V.I.-12

Oncolym

Treatment of B-cell non-Hodgkin's lymphoma.

Theragyn

Adjuvant treatment of ovarian cancer.

Mx-dnG1 or Rexin-G retroviral vector Mycobacterium avium sensitin RS-10

REXIN-G

Treatment of pancreatic cancer For use in the diagnosis of invasive Mycobacterium avium disease in immunocompetent individuals.

Mycophenolate mofetil

Cellcept

Treatment of myasthenia gravis

Mycophenolate mofetil

CellCept

Treatment of pemphigus vulgaris

Myelin myo-inositol myristoylated recombinant SCR1-3 of human APT070 complement reseptor type I N-((methyl-diazacyclohexylmethylbenzamide)-asaphenylaminothiopyrrole) mesylate N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2[(4-pyridinylmethyl)amino]-3pyridinecarboxamide, phosphate (1:2)

Treatment of multiple sclerosis. Prevention of retinopathy of prematurity in preterm infants at risk for developing retinopathy of prematurity Prevention of delayed graft function in solid organ transplant Treatment of malignant gastrointestinal stromal tumors.

Treatment of gastrointestinal stromal tumors

N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-1,4dihydro-4-oxoquinoline-3-carboxamide N-(2-amino-phenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)-methyl] benzamide dihydrobromide N-(methyl-diazacyclohexyl-methylbenzamide)azaphenyl-aminothiopyrrole) mesylate N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4methoxybenzenesulfonamide N-[3-(4',5'-bipyrimidin-2-ylamino)-4methylphenyl]-4-{[(3S)-3(dimethylamino)pyrrolidin-1-yl]methyl}-3(trifluoromethyl)benzamide N-[4-(3-amino1H-indazol-4-yl)phenyl]-N1-(2fluoro-5-methylphenyl)urea N-[4-(4-amino-2-ethyl-1H-imidazo[4,5c]quinolin-1-yl)butyl]methanesulfonamide N-[4-(4-amino-2-ethyl-lH-imidazo[4,5c]quinolin-1-yl)butyl]methanesulfonamide N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5yl)phenyl]-N'-[3,5bis(trifluoromethyl)phenyl]urea

Treatment of patients with cystic fibrosis.

Treatment of Hodgkin's lymphoma

Treatment of multiple myeloma.

Treatment of neuroblastoma Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia.

Treatment of hepatocellular carcinoma

Treatment of stages IIB-IV melanoma

Treatment of cutaneous T-cell lymphoma

Treatment of sickle cell disease

N-acetylcysteinate Lysine

Nacystelyn Dry Powder management of cystic fibrosis For the Inhaler

N-acetylcysteine N-acetylgalactosamine-4-sulfatase, recombinant human

Treatment of acute liver failure

Naglazyme

Treatment of mucopolysaccharidosis Type VI (Maroteaux-Lamy syndrome).

N-acetyl-glucosamine thiazoline

N-acetylprocainamide N-acetyl-procainamide N-acetyl-sarcosyl-glycyl-L-valyl-Dalloisoleucyl-L-threonyl-L-norvalyl-L-isoleucylL-arginyl_L-prolylethylaminde acetate

Napa

Treatment of adult Tay-Sachs disease To lower the defibrillation energy requirement sufficiently to allow automatic implantable cardioverter defibrillator therapy in those patients who could otherwise not life-threatening ventricular arrhythmias Prevention of use the device. in patients with documented procainamide-induced lupus.

Treatment of soft tissue sarcoma

Nafarelin acetate

Synarel Nasal Solution Treatment of central precocious puberty.

Naltrexone HCl Natural human lymphoblastoid interferonalpha Natural human lymphoblastoid interferonalpha

Trexan

For blockade of the pharmacological effects of exogenously administered opioids as an adjunct to the maintenance of the opioid-free state in detoxified formerly opioid-dependent individuals.

Treatment of polycythemia vera

Treatment of Behcet's disease.

Natural human lymphoblastoid interferonalpha

Treatment of papillomavirus warts in the oral cavity of HIV positive patients.

NDROGE Nebacumab

Treatment of postanoxic intention myoclonus.

Centoxin

Treatment of patients with gram-negative bacteremia which has progressed to endotoxin shock.

nelarabine

Arranon

Treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma Treatment of motor neuron disease/amyotrophic lateral sclerosis.

Neurotrophin-1 NG-29

Somatrel

Diagnostic measure of the capacity of the pituitary gland to release growth hormone.

Nifedipine

Treatment of interstitial cystitis.

Nikkomycin Z

Treatment of coccidioidomycosis

nilotinib

Tasigna

Treatment of gastrointestinal stromal tumors.

Nilotinib

Treatment of chronic myelogenous leukemia

Nimotuzumab

Treatment of glioma

niprisan

Hemoxin

Treatment of sickle cell disease

nitazoxanide

Cryptaz

Treatment for intestinal amebiasis

nitazoxanide

Alinia

Treatment of intestinal giardiasis

Nitazoxanide

Alinia

Treatment of cryptosporidiosis.

Nitisinone

Orfadin

Treatment of alkaptonuria

Nitisinone

Orfadin

Treatment of tyrosinemia type 1.

Nitric oxide

Diagnosis of sarcoidosis To reduce the risk of chronic lung disease in premature neonates

Nitric oxide

INOmax

Nitric oxide

INOmax

Treatment of persistent pulmonary hypertension in the newborn. Treatment of acute respiratory distress syndrome in adults. Treatment and prevention of cerebral vasospasm following subarachnoidmedullary and anaplastic Treatment of follicular, hemorrhage.

Nitric oxide Nitroprusside N-Methyl-2-[3-[((E)-2-pyridin-2-yl-vinyl)-1Hindazol-6-ylsulfanyl]benzamide

Axitinib

thyroid carcinoma and metastatic or locally advanced papillary thyroid cancer.

Novel Acting Thrombolytic (NAT) Nucleic acid aptamer binding to tumor cell nucleolin Nucleic acid aptamer binding to tumor cell nucleon NZ-1002

Treatment of peripheral arterial occlusion (PAO)

Treatment of pancreatic cancer

Treatment of renal cell carcinoma Enzyme replacement therapy in patients with all subtypes of Mucopolysaccharidosis I.

Obatoclax mesylate

Treatment of chronic lymphocytic leukemia

Obatoclax mesylate

Treatment of myelodysplastic syndrome

Obatoclax mesylate

Treatment of myelofibrosis Treatment of advanced malignant melanoma (Stages II,III, IV). Treatment of severe diarrhea and flushing associated

oblimersen Octreotide

Genasense

Sandostatin LARwith malignant carcinoid tumors.

Octreotide

Sandostatin LARTreatment of acromegaly.
Treatment of diarrhea associated with vasoactive

Octreotide

Sandostatin LARintestinal peptide tumors (VIPoma).

Ofloxacin

Ocuflox Ophthalmic Solution bacterial corneal ulcers. Treatment of

oglufanide disodium

Treatment of ovarian cancer

OM 401

Drepanol

Prophylactic treatment of sickle cell disease.

Omacetaxine mepesuccinate

Treatment of chronic myelogenous leukemia

Omega-3 (n-3) polyunsaturated fatty acid with all double bonds in the cis configuration

Prevention of organ graft rejection.

Omega-3 (n-3) polyunsaturated fatty acids

Omacor

Treatment of IgA nephropathy.

Oncorad Ov103

Treatment of ovarian cancer. Prevention of severe chemotherapy-induced thrombocytopenia.

Oprelvekin

Neumega

oral unfractionated heparin

Orgotein for injection

Treatment of sickle cell disease Treatment of familial amyotrophic lateral sclerosis associated with a mutation of the gene (on chromosome 21q) for copper, zinc superoxide dismutase.

ortezomib

Velcade

Treatment of multiple myeloma

Oxaliplatin

Treatment of ovarian cancer.

Oxalobacter formigenes

Treatment of primary hyperoxaluria Treatment of short stature associated with Turner's syndrome. Treatment of constitutional delay of growth and puberty.

Oxandrolone

Oxandrin

Oxandrolone Oxandrolone Oxandrolone Oxandrolone

Oxandrin Oxandrin Hepandrin

Treatment of patients with Duchenne's muscular dystrophy and Becker's muscular dystrophy. Adjunctive therapy for AIDS patients suffering from HIV-wasting syndrome. Treatment of moderate/severe acute alcoholic hepatitis in the presence of moderate protein calorie malnutrition.

oxybate

Xyrem

Treatment of narcolepsy

oxybate

Xyrem

Treatment of narcolepsy. For relief of severe intractable pain in narcotic-tolerant

Oxymorphone

Numorphan H.P.patients.

Oxypurinol p1-(uridine 5'-)-p4-(2'-deoxycytidine 5'-) tetraphosphate, tetrasodium salt P1, P4-Di(uridine 5'-tetraphosphate), tetrasodium salt

Treatment of hyperuricemia in patients intolerant to allopurinol.

For the treatment of cystic fibrosis

Treatment of cystic fibrosis.

PA mAb

Abthrax

Treatment of anthrax

Paclitaxel

Taxol

Treatment of AIDS-related Kaposi's sarcoma.

Paclitaxel

Paxene

Treatment of AIDS-related Kaposi's sarcoma.

Paclitaxel (TOCOSOL)

Treatment of non-superficial urothelial cancer Treatment of human African trypanosomiasis (sleeping sickness)

Pafuramidine maleate

Pafuramidine maleate

Treatment of malaria

pafuramidine maleate

Treatment of pneumocystis jiroveci pneuomina. Treatment of steatorrhea associated with chronic pancreatitis.

pancrelipase

VIOKASE

panobinostat

Faridak

Treatment of cutaneous T-cell lymphoma

Papain, trypsin, and chymotrypsin

Wobe-Mugos

Treatment of multiple myeloma. Treatment of sexual dysfunction in spinal cord injury patients.

Papaverine topical gel

parathyroid hormone Parvovirus B19 (recombinant VP1 and VP2; S.frugiperda cells) vaccine

Treatment of hypoparathyroidism.

MEDI-491

Prevention of transient aplastic crisis in patients with sickle cell anemia. Treatment of patulous eustachian tube.

Patul-end

Patupilone Pegademase bovine

Treatment of ovarian cancer.

Adagen

For enzyme replacement therapy for ADA deficiency in patients with severe combined immunodeficiency.

Pegaspargase PEG-glucocerebrosidase

Oncaspar Lysodase

Treatment of acute lymphocytic leukemia. For use as chronic enzyme replacement therapy in patients with Gaucher's disease who are deficient in glucocerebrosidase.

Peginterferon alfa-2a

PEGASYS

Treatment of chronic myelogenous leukemia.

Peginterferon alfa-2a PEG-interleukin-2

PEGASYS

Treatment of renal cell carcinoma. Treatment of primary immunodeficiencies associated with T-cell defects.

Pegvisomant

Somavert

Treatment of acromegaly.

Pegylated arginine deiminase

Melanocid

Treatment of invasive malignant melanoma.

Pegylated arginine deiminase Pegylated recombinant human megakaryocyte growth and development factor

Hepacid MEGAGEN

Treatment of hepatocellular carcinoma. For reducing the period of thrombocytopenia in patients undergoing hematopoietic stem cell transplantation.

Peldesine

Treatment of cutaneous T-cell lymphoma.

pemetrexed disodium Pentamidine isethionate

Alimta Nebupent

Treatment of malignant pleural mesothelioma Prevention of Pneumocystis carinii pneumonia in patients at high risk of developing this disease.

Pentamidine isethionate

Pentam 300

Treatment of Pneumocystis carinii pneumonia.

Pentamidine isethionate Pentamidine isethionate (inhalation) Pentastarch pentetate trisodium

Treatment of Pneumocystis carinii pneumonia.

Pneumopent Pentaspan

harvesting and increase the yield of leukocytes by centrifugal means. Treatment of patients with known or suspected internal contamination with plutonium, americium, or diethylenetriaminepentaacetate curium.

Prevention of Pneumocystis carinii pneumonia in patients at high risk of developing improve the As an adjunct in leukapheresis to this disease.

Pentosan polysulfate sodium

Elmiron

Treatment of interstitial cystitis. Treatment of patients with chronic lymphocytic leukemia.

Pentostatin

Nipent

Pentostatin

Nipent

Treatment of peripheral T-cell lymphomas.

Pentostatin

Nipent

Treatment of cutaneous T-cell lymphoma.

Pentostatin for injection

Nipent

Treatment of hairy cell leukemia.

Peptide 144 TGF beta-1 inhibitor

Treatment of systemic sclerosis

Peptide 144 TGF beta-1-inhibitor

Treatment of localized scleroderma

Peptidomimetic analog of hexarelin

Diagnosis of growth hormone deficiency Treatment of acute respiratory distress disease (ARDS) in adults For use in the ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia.

Perflubron

LiquiVent

Perfosfamide

Pergamid

Pergolide

Permax

Treatment of Tourette's syndrome. For use as an adjunct to surgery, radiation therapy and chemotherapy for the treatment of patients with primary or recurrent malignant glioma.

Phenylacetate

Phenylalanine ammonia-lyase

Phenylase

Treatment of hyperphenylalaninemia.

Phenylbutyrate

Treatment of acute promyelocytic leukemia. Treatment of ileal pouch anal anastomosis related fecal incontinence

phenylephrine

Phosphocysteamine

Treatment of cystinosis. Treatment of xerostomia induced by radiation therapy for head and neck cancer.

Pilocarpine

Salagen

Pilocarpine HCl

Salagen

Treatment of xerostomia and keratoconjunctivitis sicca in Sjogren's syndrome patients.

Piracetam Piritrexim isethionate Plasmid DNA vector expressing cystic fibrosis transmembrane gene

Nootropil

Treatment of myoclonus. Treatment of infections caused by Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium-intracellulare.

Treatment of cystic fibrosis

Plevitrexed

Plevitrexed

Treatment of ovarian cancer

Plevitrexed

Plevitrexed

Treatment of gastric (stomach) cancer

Plitidepsin

Aplidin

Treatment of acute lymphoblastic leukemia

Plitidepsin

Aplidin

Treatment of multiple myeloma

polifeprosan 20 with carmustine

Gliadel

Treatment of malignant glioma

polifeprosan 20 with carmustine Poloxamer 188

Gliadel

Treatment of malignant glioma. Treatment of vasospasm in subarachnoid hemorrhage patients following surgical repair of a ruptured cerebral aneurysm.

Poloxamer 188

Flocor

Treatment of sickle cell crisis.

Poloxamer 188

Florcor

Treatment of severe burns requiring hospitalization.

Poloxamer 331

Protox

Initial therapy of toxoplasmosis in patients with AIDS.

Poly I: poly C12U

Ampligen

Treatment of renal cell carcinoma. Treatment of invasive metastatic melanoma (stage IIb, III, IV).

Poly I: poly C12U

Ampligen

Poly I: poly C12U

Ampligen

Treatment of chronic fatigue syndrome.

Poly I: poly C12U

Ampligen

Treatment of AIDS. To control the clinical consequences of hyperuricemia in patients with severe gout in whom conventional therapy is contraindicated or has been ineffective. Treatment of hyperuricemia in patients with gout refractory to conventional therapy or in whom conventional therapy is contraindicated Prophylaxis of hyperuricemia in cancer patients prone to develop tumor lysis syndrome during chemotherapy. Treatment of tumor lysis syndrome in cancer patients undergoing chemotherapy.

Polyethylene glycol (PEG)-uricase

Polyethylene glycol-modified uricase Polyethylene glycol-modified uricase Polyethylene glycol-modified uricase

Zurase Zurase

Poly-ICLC

Hiltonol

polyinosinic-polycytidilic acid

Poly-ICLC

Treatment of primary brain tumors. Treatment of flavivirus infections including those due to West Nile, Japanese encephalitis, dengue, St. Louis encephalitis, yellow fever, Murray valley, and Banzai viruses

polyinosinic-polycytidilic acid

Poly-ICLC

As an adjuvant to smallpox vaccination

polyinosinic-polycytidilic acid (Poly-ICLC)

Hiltonol

Treatment for orthopox virus infections

Polymeric oxygen

Treatment of sickle cell anemia.

Polyvalent, shed-antigen melanoma vaccine Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared and coated with anti-MHC-1 Ab for intracerebral NeuroCell-PD implantation

Treatment of stage IIb to and stage IV melanoma Treatment of Hoehn and Yahr stage 4 and 5 Parkinson's disease.

Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared for NeuroCell-PD intracerebral implantation. Porcine fetal neural gabaergic cells and/or precursors aseptically prepared and coated with anti-MHC-1 Ab for intracerebral NeuroCell-HD implantation Porcine fetal neural gabaergic cells and/or precursors aseptically prepared for intracerebral implantation for Huntington's NeuroCell-HD disease. Porcine Sertoli cells aseptically prepared for intracerebral co-implantation with fetal neural tissue porfimer

Treatment of Hoehn and Yahr stage 4 and 5 Parkinson's disease.

Treatment of Huntington's disease.

Treatment of Huntington's disease. Treatment of Hoehn and Yahr stage four and five Parkinson's disease. For the ablation of High-Grade Dysplasia in Barrett's Esophagus in patients who are not considered to be candidates for esophagectomy

N-Graft Photofrin

Porfimer sodium

Photofrin

Treatment of cholangiocarcinoma For the photodynamic therapy of patients with primary or recurrent obstructing (either partially or completely) esophageal carcinoma. For the photodynamic therapy of patients with transitional cell carcinoma in situ of the urinary bladder.

Porfimer sodium Porfimer sodium

Photofrin Photofrin

Porfiromycin

Promycin

Treatment of cervical cancer.

Porfiromycin

Promycin

Treatment of head and neck cancer.

Posaconazole Potassium citrate

Posoril Urocit-K

Treatment of zygomycosis For avoidance of the complication of calcium stone formation in patients with uric lithiasis. Prevention of calcium renal stones in patients with hypocitraturia.

Potassium citrate

Urocit-K

Potassium citrate Potassium citrate and citric acid Potassium Iodide Oral Solution

Urocit-K

Prevention of uric acid nephrolithiasis. For the dissolution and control of uric acid and cysteine calculi in the urinary tract.

ThyroShield

For use as a thyroid blocking agent in pediatric patients exposed to radiactive iodine

potassium sodium aluminosilicate

For treatment of poisoning by or exposure to cesium. Treatment of myelodysplastic syndromes (MDS) requiring therapy.

PR1 Vaccine

PR1 Vaccine

Treatment of acute myelogenous leukemia

PR1 Vaccine Pr-122 (redox-phenytoin)

Treatment of chronic myelogenous leukemia. For the emergency rescue treatment of status epilepticus, grand mal type.

PR-225 (redox-acyclovir)

Treatment of herpes simplex encephalitis in individuals afflicted with AIDS.

PR-239 (redox penicillin G) Pr-320 (molecusol-carbamazepine)

Treatment of AIDS associated neurosyphilis. For the emergency rescue treatment of status epilepticus, grand mal type.

Pralatrexate Pramiracetam Sulfate

Treatment of T-cell lymphoma For the management of cognitive dysfunction and enhancement of antidepressant activity associated with electroconvulsive therapy.

Praziquantel

Treatment of neurocysticercosis.

Prednimustine Primaquine phosphate

Sterecyt

Treatment of malignant non-Hodgkin's lymphomas. For use in combination with clindamycin hydrochloride in the treatment of Pneumocystis carinii pneumonia associated with AIDS.

Procarbazine HCl Progesterone Propamidine isethionate 0.1% ophthalmic solution

Matulane

Treatment of malignant glioma of pregnancy in Establishment and maintenance women undergoing in vitro fertilization or embryo transfer procedures.

Brolene

Treatment of acanthamoeba keratitis. Treatment of Fontaine Stage IV chronic critical limb ischemia. Treatment of ischemic ulceration of the lower limbs due to peripheral arterial disease.

Prostaglandin E1 enol ester (AS-013) Prostaglandin E1 in lipid emulsion

Circulase Lipo-PGE1

Protaxel

Protein C concentrate Protein C concentrate

Ceprotin

Treatment of ovarian cancer For replacement therapy in congenital protein C deficiency for the prevention and treatment of thrombosis, pulmonary emboli, and purpura fulminans. For use in the prevention and treatment of purpura

Protein C Concentrate (human) Vapor Heated, Immuno fulminans in meningococcemia.

Protein C concentrate Protirelin

For replacement therapy in patients with congenital or acquired protein C deficiency for the prevention and treatment of warfarin-induced skin necrosis during Protein C Concentrate (human) Vapor Heated, Immuno oral anticoagulation. Prevention of infant respiratory distress syndrome associated with prematurity.

Protirelin injection

Treatment of amyothrophic lateral sclerosis. Prevention and treatment of infant respiratory distress syndrome.

Pulmonary surfactant replacement Pulmonary surfactant replacement, porcine Purified extract of Pseudomonas aeruginosa

Curosurf ImmuDyn

For the treatment and prevention of respiratory distress syndrome in premature infants. Treatment of immune thrombocytopenia purpura where it is required to increase platelet counts.

Purified type II collagen

Colloral

Treatment of juvenile rheumatoid arthritis.

Pyruvate Quinacrine hydrochloride

Treatment of interstitial lung disease. For prevention of recurrence of pneumothorax in patients at high risk of recurrence.

quinine Sulfate

Treatment of malaria

R-(-)-gossypol

Treatment of chronic lymphocytic leukemia.

rAAV2-CB-hRPE65

Treatment of type II Leber's Congential Amaurosis

Induction treatment to prevent rejection and to minimize maintenance immunosupression in pediatric Rabbit anti-human thymocyte globulin (rATG) Thymoglobulin liver transplant recipients Reduction of the risk of breast cancer in postmenopausal women

Raloxifene

Evista

Ranprinase

Onconase

Treatment for malignant mesothelioma

Rapamycin

Treatment of tuberous sclerosis complex

Rapamycin (mTOR) inhibitor

Treatment of bone sarcoma

rasburicase

Elitek

Treatment of malignancy-associated or chemotherapy-induced hyperuricemia.

recombinant adeno-associated virus alpha 1rAAV-AAT antitrypsin vector

Treatment of alpha1-antitrypsin deficiency

Recombinant anti-CD40 monoclonal antibody

Treatment of chronic lymphocytic leukemia

Recombinant anti-CD-40 monoclonal antibody Recombinant bactericidal/permeabilityincreasing protein

Treatment of multiple myeloma

Neuprex

Treatment of severe meningococcal disease.

recombinant chimeric monoclonal antibody to Anthim anthrax

Treatment of exposure to B. anthracis spores

Recombinant coagulation factor VIIa

Novoseven

Treatment of diffuse alveolar hemorrhage

Recombinant deriative of C3 transferase Recombinant Epstein-Barr virus gp350 glycoprotein vaccine recombinant fusion protein with a truncated form of the cytotoxic protein Pseudomonas exotoxin

Cethrin

Proxinium

Treatment of acute spinal cord injury Prevention of post-transplantation lymphoproliferative disorders in pediatric recipients of solid-organ transplantation Treatment of Ep-CAM-positive squamous cell carcinoma of the head and neck

Recombinant glycine2-human glucagon-like peptide-2

Treatment of short bowel syndrome.

Recombinant human acid alpha-glucosidase

Myozyme

Treatment of glycogen storage disease type II.

Recombinant human alpha 1-antitrypsin

Prevention of bronchopulmonary dysplasia

recombinant human alpha 1-antitrypsin (rAAT)

Treatment of cystic fibrosis

recombinant human alpha-1 antitrypsin

Treatment of cystic fibrosis. To delay progression of chronic obstructive pulmonary disease resulting from AAT deficiency-mediated emphysema and bronchiectasis

recombinant human alpha-1 antitrypsin (rAAT) Recombinant Human Alpha-Fetoprotein (rhAFP)

Treatment of myasthenia gravis

Recombinant human alpha-mannosidase Recombinant human anti-GDF-8 (growth and differentiation factor-8) antibody Recombinant human antithrombin III

Treatment of alpha-mannosidosis Treatment of Duchenne and Becker muscular dystrophies Treatment of antithrombin III dependent heparin resistance requiring anticoagulation.

Recombinant human C1 inhibitor Recombinant human C1 inhibitor Recombinant human C1-esterase inhibitor Recombinant human C1-esterase inhibitor

Treatment of capillary leakage syndrome Prevention and/or treatment of delayed graft function after solid organ transplantationangioedema caused Treatment of (acute attacks of) by hereditary or acquired C1-esterase inhibitor deficiency. Prophylactic treatment of angioedema caused by hereditary or acquired C1-esterase inhibitor deficiency.

Recombinant human CD4 immunoglobulin G Recombinant human Clara Cell 10kDa protein

Treatment of AIDS resulting from infection with HIV-1. Prevention of neonatal bronchopulmonary dysplasia in premature neonates with respiratory distress syndrome.

recombinant human endostatin protein

Treatment of neuroendocrine tumors.

recombinant human endostatin protein recombinant human fibroblast growth factor20 Recombinant human gelsolin

Treatment of metastatic melanoma

Treatment of radiation induced oral mucositis Treatment of acute and chronic respiratory symptoms of bronchiectasis.

Recombinant human gelsolin Recombinant human granulocyte colony stimulating factor Recombinant human highly phosphorylated acid alpha-glucosidase

Treatment of the respiratory symptoms of cystic fibrosis.

TBD

Prevention of implantation failure For enzyme replacement therapy in patients with all subtypes of glycogen storage disease type II (GSDII, Pompe Disease)

Recombinant human insulin-like growth factor IGF-1 1 Recombinant human insulin-like growth factor IGF-1 1 Recombinant human insulin-like growth factor-I Recombinant human insulin-like growth factor-I Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3

PV802

Treatment of growth hormone receptor deficiency. Treatment of antibody-mediated growth hormone resistance in patients with isolated growth hormone deficiency Ia. Treatment of short-bowel syndrome as a result of resection of the small bowel or as a result of congenital dysfunction of the intestines.

Treatment of post-poliomyelitis syndrome.

Treatment of major burns that require hospitalization.

Recombinant human interleukin-12

Treatment of renal cell carcinoma. Treatment of stage II (T4), III or IV malignant melanoma. Reducing the incidence and severity of radiationinduced xerostomia. For use in association with recombinant human follicle stimulating hormone for the treatment of women with chronic anovulation due to hypogonadotropic hypogonadism. Treatment of lipase deficiencies, including Wolman Disease and cholesteryl ester storage disease

Recombinant Human Interleukin-21 (rIL-21) Recombinant human keratinocyte growth factor

Recombinant human luteinizing hormone

Luveris

Recombinant human lysosomal acid lipase or Cholestrase cholesteryl ester hydrolase

Recombinant human microplasmin recombinant human monoclonal antibody to hsp90

Treatment of peripheral arterial occlusion

Mycograb

Treatment of invasive candidiasis

Recombinant human nerve growth factor

Treatment of HIV-associated sensory neuropathy.

recombinant human neutrophil inhibitor (hNE) Recombinant human platelet derived growth factor BB recombinant human porphobilinogen deaminase recombinant human porphobilinogen deaminase, erythropoetic form

Treatment of cystic fibrosis

treatment of osteonecrosis of the jaws.

Porphozyme

Treatment of acute intermittent porphyria attacks Treatment of acute intermittent porphyria preventing attacks

Recombinant human relaxin Recombinant human thrombopoietin

Treatment of progressive systemic sclerosis. For use in accelerating platelet recovery in patients undergoing hematopoietic stem cell transplantation.

Recombinant humanized MAb 5c8

Prevention of rejection of solid organ transplants. Prevention of rejection of pancreatic islet cell transplants. Prevention and treatment of Factor VIII/Factor IX inhibitors in patients with hemophilia A or B.

Recombinant humanized MAb 5c8 Recombinant humanized MAb 5c8 Recombinant humanized monclonal antibody 5c8 Recombinant humanized monoclonal antibody 5c8 recombinant inhibitor of human plasma kallikrein Recombinant methionyl brain-derived neurotrophic factor

Treatment of immune thrombocytopenic purpura.

Treatment of systemic lupus erythematosus.

Treatment of angioedema

Treatment of amyotrophic lateral sclerosis.

recombinant ovine interferon tau Recombinant Porcine Factor VIII, B-domain Deleted

Tauferon

Treatment of pediatric multiple sclerosis Treatment and prevention of episodic bleeding in patients with inhibitor antibodies to human coagulation factor VIII Prevention of delayed graft function in renal transplant patients Prevention of ischemia reperfusion injury in all solid organ transplants For use as enzyme replacement therapy for patients with types I, II, or III Gaucher disease.

Recombinant P-Selectin glycoprotein ligand Recombinant P-selectin glycoprotein ligandimmunoglobulin Ig Recombinant retroviral vector glucocerebrosidase Recombinant secretory leucocyte protease inhibitor Recombinant secretory leucocyte protease inhibitor

Treatment of cystic fibrosis.

Treatment of congenital alpha-1 antitrypsin deficiency.

Recombinant soluble human CD4

Receptin

Treatment of acquired immunodeficiency syndrome.

Recombinant soluble human CD4 (rCD4)

Treatment of AIDS in patients infected with HIV virus. Treatment of multiple sclerosis patients who are both HLA-DR2 positive and autoreactive to myelin oligodendrocyte glycoprotein residues 35-55

Recombinant T-cell receptor ligand Recombinant truncated SPINT2 protease inhibitor

Treatment of cystic fibrosis

Recombinant urate oxidase

Prophylaxis of chemotherapy-induced hyperuricemia.

Reduced L-glutathione

Cachexon

Treatment of AIDS-associated cachexia.

Remacemide

Ecovia

Treatment of Huntington's disease. Prevention of delayed graft function in solid organ transplant

Reparixin

repository corticotropin or adrenocorticotropic H.P. Acthar Gel Treatment of infantile spasms hormone

resiniferatoxin Respiratory Syncytial Virus Immune Globulin (human)

Treatment of intractable pain at end-stage disease Treatment of respiratory syncytial virus lower respiratory tract infections in hospitalized infants and Hypermune RSVyoung children. Prophylaxis of respiratory syncytial virus lower respiratory tract infections in infants and young children at high risk of RSV disease.

Respiratory syncytial virus immune globulin (Human)

Respigam

R-etodolac

Treatment of chronic lymphocytic leukemia Treatment of X linked severe combined immune deficiency disease

retroviral gamma-c cDNA containing vector

Retroviral vector, R-GC and GC gene 1750 Reviparin sodium Reviparin sodium

Treatment of Gaucher disease.

Clivarine Clivarine

Treatment of deep vein thrombosis which may lead to pulmonary embolism in pediatric patients Long-term treatment of acute deep vein trombosis with or without pulmonary embolism in pregnant patients

RGG0853, E1A lipid complex rhIGF-I/rhIGFBP-3

SomatoKine

Treatment of ovarian cancer. resistance syndromes Treatment of extreme insulin (type A, Rabson-Mendenhall syndrome, Leprechaunism, Type B syndrome)

rh-microplasmin

Adjunct to surgery in cases of pediatric vitrectomy

Rho (D) immune globulin intravenous (human) WinRho SD

Treatment of immune thrombocytopenic purpura.

Ribavirin

Virazole

Treatment of hemorrhagic fever with renal syndrome.

ribavirin Ricin (blocked) conjugated murine mca (antib4) Ricin (blocked) conjugated murine MCA (antiB4) Ricin (blocked) conjugated murine MCA (antimy9)

REBETOL

Treatment of chronic hepatitis C in pediatric patients For the ex-vivo purging of leukemic cells from the bone marrow of non-T cell acute lymphocytic leukemia patients who are in complete remission.

Treatment of B-cell leukemia and B-cell lymphoma. Treatment of myeloid leukemia, including AML, and blast crisis of CML.

Ricin (blocked) conjugated murine MCA (antimy9) Ricin (blocked) conjugated murine MCA (n901) Ricin (blocked) conjugated murine monoclonal antibody (CD6) Rifabutin

For use in the ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia.

Mycobutin

Treatment of small cell lung cancer. Treatment of cutaneous T-cell lymphomas, acute Tcell leukemia-lymphoma, and related mature T-cell malignancies. Prevention of disseminated Mycobacterium avium complex disease in patients with advanced HIV infection. Treatment of disseminated Mycobacterium avium complex disease.

Rifabutin

Rifalazil Rifampin

Treatment of pulmonary tuberculosis.

Rifadin I.V.

For antituberculosis treatment where use of the oral form of the drug is not feasible.

Rifampin, isoniazid, pyrazinamide Rifapentine

Rifater Priftin

For the short-course treatment of tuberculosis. Prophylactic treatment of Mycobacterium avium complex in patients with AIDS and a CD4+ count less than or equal to 75/mm3. Treatment of Mycobacterium avium complex in patients with AIDS.

Rifapentine

Priftin

Rifapentine

Priftin

Treatment of pulmonary tuberculosis.

Rifaximin

Normix

Treatment of hepatic encephalopathy

RII retinamide

Treatment of myelodysplastic syndromes.

Riluzole

Rilutek

Treatment of Huntington's disease.

Riluzole

Rilutek

Treatment of amyotrophic lateral sclerosis.

risedronate sodium

Actonel

rituximab

Rituxan

Treatment of patients with osteogenesis imperfecta. Treatment of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (Wegener's Granulomatosis, Microscopic Polyangiitis, and ChurgStrauss Syndrome)

rituximab

Rituxan

Treatment of immune thrombocytopenic purpura

rituximab

Rituxan

Treatment of non-Hodgkin's B-cell lymphoma.

rituximab

Rituxan

Treatment of chronic lymphocytic leukemia

rofecoxib

VIOXX

Treatment of juvenile rheumatoid arthritis

rolespimycin hydrochloride

Treatment for gastrointestinal stromal tumor

romidepsin Roquinimex

Linomide

Treatment of non-Hodgkin T-cell lymphomas To prolong time to relapse in leukemia patients who have undergone autologous bone marrow transplantation.

Rose Bengal Disodium

Treatment of metastatic melanoma

rSP-C lung surfactant

Venticute

Treatment of adult respiratory distress syndrome. For use in patients with pneumonia or aspiration of gastric contents leading to intubation, mechanical ventilation, and severe oxygen impairment Treatment of pediatric patients infected with human immunodeficiency virus and acquired immunodeficiency syndrome

rSP-C surfactant rubitecan

Venticute

Rufinamide

Treatment of Lennox-Gastaut Syndrome.

S(-)-3-[3-amino-phthalimido]-glutaramide

Treatment of multiple myeloma Treatment of congenital sucrase-isomaltase deficiency.

Sacrosidase

Sucraid

S-adenosylmethionine

Treatment of AIDS-myelopathy.

salirasib

Sargramostim

Leukine

Treatment of panreatic cancer. Treatment of neutropenia associated with bone marrow transplant, for the treatment of graft failure and delay of engraftment, and for the promotion of early engraftment. To reduce neutropenia and leukopenia and decrease the incidence of death due to infection in patients with acute myelogenous leukemia.

Sargramostim

Leukine

sarsasapogenin

Treatment of amyotrophic lateral sclerosis (ALS)

Satumomab pendetide

Oncoscint CR/OV Detection of ovarian carcinoma.

SB-408075

For pancreatic cancer Treatment of patients with CD55 (sc-1) positive gastric tumors

SC-1 monoclonal antibody

SCH 58500

Treatment of primary ovarian cancer.

SDF-1 (108) Lysine Dlmer

Treatment of osteogenic sarcoma

Secalciferol

Osteo-D

Treatment of familial hypophosphatemic rickets.

Secretory leukocyte protease inhibitor

Selegiline HCl Sermorelin acetate

Eldepryl Geref

Treatment of bronchopulmonary dysplasia. As an adjuvant to levodopa and carbidopa treatment of idiopathic Parkinson's disease (paralysis agitans), postencephalitic Parkinsonism, and symptomatic Parkinsonism. Treatment of idiopathic or organic growth hormone deficiency in children with growth failure. Adjunct to gonadotropin therapy in the induction of ovulation in women with anovulatory or oligo-ovulatory infertility who fail to ovulate in response to adequate treatment with clomiphene citrate alone and gonadotropin therapy alone.

Sermorelin acetate

Geref

Sermorelin acetate

Geref

Treatment of AIDS-associated catabolism/weight loss.

Serratia marcescens extract (polyribosomes)

Imuvert

Treatment of primary brain malignancies.

SGN-30 (anti-CD30 antibody)

Treatment of CD30 positive T-cell lymphomas

SGN-30 (anti-CD30 mAb)

Treatment of Hodgkin's disease

SGN-40 (anti-CD40 antibody)

Treatment of multiple myeloma.

Short chain fatty acid enema Short chain fatty acid solution

Colomed Colomed

Treatment of chronic radiation proctitis. Treatment of the active phase of ulcerative colitis with involvement restricted to the left side of the colon.

Silver sulfadiazine and cerium nitrate

Flammacerium Prevention of mortality in severely burned patients.

siplizumab Sitaxsentan Sodium SK&F 110679

Treatment of T-cell lymphomas arterial hypertensionin For the treatment of pulmonary the absence of chronic obstructive pulmonary disease or congestive heart failure For the long term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion.

Sodium aluminosilicate Sodium ascorbate and menadione sodium bisulfite

Apatone

Treatment of chronic hepatic encephalopathy Treatment of metastatic or locally advanced inoperable transitional cell carcinoma of the urothelium (stage III and IV bladder cancer) Treatment of homozygous familial hypercholesterolemia.

Sodium dichloroacetate

Sodium dichloroacetate

Treatment of congenital lactic acidosis.

Sodium dichloroacetate

Treatment of congenital lactic acidosis.

Sodium dichloroacetate sodium dichloroacetate

Treatment of lactic acidosis in patients with severe malaria. Use as an antidote in the management of systemic monochloroacetic acid poisoning

Sodium dichloroacetate Sodium Monomercaptoundecahydro-closododecaborate Sodium monomercaptoundecahydro-closododecaborate

Ceresine Borocell

Treatment of severe head injury. For use in boron neutron capture therapy (BNCT) in the treatment of glioblastoma multiforme. For use in conjunction with a thermal or epithermal neutron beam in boron nuclear capture therapy of glioblastoma multiforme. Treatment of vaso-occlusive crisis associated with sickle cell disease

Sodium nitrite

Sodium nitrite

Treatment of cyanide poisoning Prevention of vasospasm associated with subarachnoid hemorrhage

Sodium nitrite

Sodium nitrite/sodium thiosulfate Sodium phenylacetate/sodium benzoate 10%/10% Injection

Cyanide Antidote Packageof cyanide poisoning Treatment

Ammonul

Treatment of grade III and VI hepatic encephalopathy

Sodium phenylbutyrate

Treatment of spinal muscular atrophy

Sodium phenylbutyrate

Buphenyl

Treatment of spinal muscular atrophy For use as an adjuct to surgery, radiation therapy and chemotherapy for the treatment of patients with primary or recurrent malignant glioma. Treatment of urea cycle disorders: carbamylphosphate synthetase deficiency, ornithine transcarbamylase deficiency, and arginiosuccinic acid synthetase deficiency. Treatment for sickling disorders, which include S-S hemoglobinopathy, S-C hemoglobinopathy, and Sthalassemia hemoglobinopathy.

Sodium phenylbutyrate

sodium phenylbutyrate

Buphenyl

sodium phenylbutyrate

Sodium pyruvate

Treatment of cystic fibrosis

Sodium stibogluconate

Treatment of cutaneous leishmaniasis Prevention of platinum-induced ototoxicity in pediatric patients

Sodium thiosulfate

Sodium thiosulfate and sodium nitrite

Treatment of cyanide poisoning

Sodium thiosulfate, sodium nitrite, amyl nitrite Cyanide Antidote Packageof cyanide poisoning Treatment

Solasonine and solamargine

Coramsine

Treatment of renal cell carcinoma Treaatment of high risk stage II, stage III and stage IV melanoma Prevention of post-cardiopulmonary bypass syndrome in children undergoing cardiopulmonary bypass. Prevention or reduction of adult respiratory distress syndrome.

Solasonine and solamargine Soluble complement receptor type 1 Soluble recombinant human complement receptor type 1 solvent/detergent treated non-blood group specific human coagulation active plasma

Coramsine

UNIPLAS

Somatostatin

Zecnil

Treatment of thrombotic thrombocytopenic purpura Adjunct to the non-operative management of secreting cutaneous fistulas of the stomach, duodenum, small intestine (jejunum and ileum), or pancreas.

Somatostatin

Treatment of bleeding esophageal varices. Treatment of short stature associated with Turner's syndrome. For long-term treatment of children who have growth

Somatrem for injection Somatrem for injection Somatropin

Protropin Protropin Humatrope

failure due to a lack of adequate endogenous growth hormone secretion. Treatment of short stature in pediatric patients with short stature homeobox-containing gene (SHOX) deficiency

Somatropin

Norditropin

Treatment of short stature in patients with Noonan syndrome Treatment of short stature associated with Turner's syndrome. Treatment of short stature associated with Turner syndrome. Adjunct for the induction of ovulation in women with infertility due to hypogonadotropic hypogonadism or bilateral tubal occlusion or unexplained infertility, who are undergoing in vivo or in vitro fertilization procedures.

Somatropin

Norditropin

Somatropin

Humatrope

Somatropin

Norditropin

Somatropin

Biotropin

Treatment of cachexia associated with AIDS.

Somatropin Somatropin

Genotropin Serostim

Treatment of adults with growth hormone deficiency. Treatment of patients with HIV-associated adipose redistribution syndrome For use in the long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion. For the enhancement of nitrogen retention in hospitalized patients suffering from severe burns. Treatment of idiopathic or organic growth hormone deficiency in children with growth failure.

Somatropin Somatropin (rDNA) Somatropin (rDNA origin)

Nutropin Saizen Saizen

Somatropin (rDNA origin)

Long-term treatment of children who have growth failure due to a lack of adequate endogenous growth Nutropin Depot hormone secretion.

Somatropin (rDNA origin) injection Somatropin (r-DNA) Somatropin (r-DNA) for injection

Norditropin Zorbtive Serostim

Treatment of growth failure in children due to inadequate growth hormone secretion. For use alone or in combination with glutamine in the treatment of short bowel syndrome. Treatment of children with AIDS-associated failure-tothrive including AIDS-associated wasting. Treatment of short stature in patients with Prader-Willi syndrome. Treatment of growth failure in children who were born small for gestational age. For the long-term treatment of children who have growth failure due to inadequate secretion of normal endogenous growth hormone. As replacement therapy for growth hormone deficiency in adults after epiphyseal closure. Treatment of growth retardation associated with chronic renal failure.

Somatropin [rDNA]

Genotropin

somatropin [rDNA] Somatropin for injection Somatropin for injection

Genotropin Humatrope Nutropin

Somatropin for injection

Nutropin

Somatropin for injection

Serostim

Treatment of AIDS-associated catabolism/weight loss.

Somatropin for injection

Nutropin

Treatment of short stature associated with Turner's syndrome.

Sorafenib

Nexavar

Treatment of hepatocellular carcinoma

Sorafenib

Nexavar

Treatment of stage IIB through stage IV melanoma

Sorafenib Sorivudine

Nexavar BRAVAVIR

Treatment of renal cell carcinoma. Treatment of herpes zoster (shingles) in immunocompromised patients. Prevention of life threatening ventricular tachyarrhythmias. Treatment of life-threatening ventricular tachyarrhythmias. For symptomatic relief and parasitic cure of chronic cryptosporidiosis in patients with immunodeficiency.

Sotalol HCl

Betapace

Sotalol HCl Spiramycin

Betapace Rovamycine

squalamine lactate

Treatment of ovarian cancer refractory or resistant to standard chemotherapy

SS1(dsFv)-PE38

Treatment of epithelial ovarian cancer

SS1(dsFv)-PE38

Treatment of malignant mesothelioma Treatment of patients with B-chronic lymphocytic leukemia.

ST1-RTA immunotoxin (SR 44163)

ST1-RTA immunotoxin (SR 44163) Staphylococcus aureus Immune Globulin (Human)

Prevention of acute graft versus host disease in allogenic bone marrow transplantation.

Altastaph

Prophylaxis against Staphylococcus aureus infections in low birth weight neonates For use as hematopoietic support in patients with relasped or refractory hematologic malignancies who are receiving high-dose therapy

Stem and progenitor cells derived from ex vivo expanded allogeneic umbilical cord blood StemEx

Sterile talc

Steritalc

Treatment of malignant pleural effusion.

Sterile talc

Steritalc

Treatment of pneumothorax.

Sterile talc powder

Sclerosol Intrapleural Aerosol Treatment of malignant pleural effusion.

SU101

Treatment of ovarian cancer.

SU101

Treatment of malignant glioma.

Succimer Succimer

Chemet Chemet

Treatment of mercury intoxication. Prevention of cystine kidney stone formation in patients with homozygous cystinuria who are prone to stone development.

Succimer Sucralfate Sucralfate suspension Sucralfate suspension

Chemet capsules Treatment of lead poisoning in children.
Treatment of oral mucositis and stomatitis following radiation therapy for head and neck cancer. Treatment of oral complications of chemotherapy in bone marrow transplant patients. Treatment of oral ulcerations and dysphagia in patients with epidermolysis bullosa. For use in combination with pyrimethamine for the treatment of Toxoplasma gondii encephalitis in patients with and without AIDS.

Sulfadiazine

Sulfapyridine

Superoxide dismutase (human)

Treatment of dermatitis herpetiformis. For protection of donor organ tissue from damage or injury mediated by oxygen-derived free radicals that are generated during the necessary periods of ischemia (hypoxia, anoxia), and especially reperfusion, associated with the operative procedure.

Superoxide dismutase (recombinant human)

Oxsodrol

Prevention of reperfusion injury to donor organ tissue.

Suramin Surface active extract of saline lavage of bovine lungs

Metaret Infasurf

Treatment of hormone-refractory prostate cancer. Treatment and prevention of respiratory failure due to pulmonary surfactant deficiency in preterm infants. Prevention and treatment of neonatal respiratory distress syndrome.

Surfactant (human) (amniotic fluid derived)

Human Surf

Synsorb Pk Synthetic human secretin Synthetic human secretin Synthetic human secretin Synthetic human secretin

Treatment of verocytotoxogenic E. coli infections. For use in conjunction with diagnostic procedures (including ERCP) for pancreatic disorders to increase pancreatic fluid secretion For use in the diagnosis of gastrinoma associated with Zollinger-Ellison syndrome. For use in conjunction with diagnostic procedures for pancreatic disorders to increase pancreatic fluid secretion. For use in obtaining desquamated pancreatic cells for cytopathologic examination in pancreatic carcinoma. For use in the evaluation of exocrine pancreas function. For use in obtaining desquamated pancreatic cells for cytopathologic examination in pancreatic carcinoma.

Synthetic human secretin Synthetic porcine secretin

Synthetic porcine secretin

For use in the evaluation of exocrine pancreas function. For use in conjunction with diagnostic procedures for pancreatic disorders to increase pancreatic fluid secretion. For use in the diagnosis of gastrinoma associated with Zollinger-Ellison syndrome. To prevent cutaneous neoplasms and other skin abnormalities in xeroderma pigmentosum. Prophylaxis of organ rejection in patients receiving heart transplants.

Synthetic porcine secretin Synthetic porcine secretin T4 endonuclease V, liposome encapsulated

Tacrolimus

Prograf

Tacrolimus

Prograf

Prophylaxis of graft-versus-host-disease.

Tadalafil

Cialis

Treatment of pulmonary arterial hypertension

TAK-603

Treatment of Crohn's disease.

talactoferrin alfa

Treatment of non-small cell lung cancer

talactoferrin alfa

Treatment of renal cell carcinoma

talactoferrin alfa

For the treatment of graft versus host disease

talactoferrin alfa

For the prevention of graft-versus-host disease

Talotrexin T-cell depleted stem cell enriched cellular product from peripheal b lood stem cells

Treatment of acute lymphoblastic leukemia

Treatment of chronic granulomatous disease

TD-K6a.513a.12

ReveKer

Treatment of pachyonychia congenita

Technetium Tc 99m pterotetramide Technetium Tc99m anti-melanoma murine monoclonal antibody

For the identification of ovarian carcinomas.

Oncotrac Melanoma Imaging Kit malignant melanoma.

For use in detecting, by imaging, metastases of Diagnostic imaging in the evaluation of the extent of disease in patients with histologically confirmed diagnosis of non-Hodgkin's B-cell lymphoma, acute Bcell lymphoblastic leukemia (in children and adults), and chronic B-cell lymphocytic leukemia. Detection of hCG producing tumors such as germ cell

Technetium Tc99m murine monoclonal antibody (IgG2a) to B cell Technetium Tc99m murine monoclonal antibody to hCG Technetium Tc99m murine monoclonal antibody to human AFP Technetium Tc99m murine monoclonal antibody to human alpha-fetoprotein Technetium Tc99m rh-Annexin V

LymphoScan

Immuraid, hCG-Tc-99m and trophoblastic cell tumors.

AFP-Scan

Detection of alpha-fetoprotein producing germ cell tumors. Detection of hepatocellular carcinoma and Diagnosis or assessment of rejection status in heart, heart-lung, single lung, or bilateral lung transplants.

Immuraid, AFP-Scan hepatoblastoma. Apomate

Tegafur/gimeracil/oteracil

Treatment of gastric cancer Treatment of pulmonary infections caused by Burkholderia cepacia Palliative treatment of recurrent, refractory or second primary squamous cell carcinomas of the head and neck in patients considered to be incurable with surgery or radiotherapy.

temocillin sodium

Negaban

Temoporfin

Foscan

temozolomide

Temodar

Treatment of malignant glioma

Temozolomide

Temodal

Treatment of newly diagnosed high grade glioma

Temozolomide

Temodal

Treatment of advanced metastatic melanoma.

Temozolomide

Temodar

Treatment of recurrent malignant glioma.

Temsirolimus

Torisel

Treatment of renal cell carcinoma Treatment of refractory childhood acute lymphocytic Diagnostic agent to assist in establishing the diagnosis in patients presenting with clinical and laboratory evidence of hypocalcemia due to either hypoparathyroidism or pseudohypoparathyroidism.

Teniposide

Vumon for injection leukemia.

Teriparatide

Parathar

Teriparatide

Parathar

Treatment of idiopathic osteoporosis.

Terlipressin

Glypressin

Treatment of bleeding esophageal varices.

Terlipressin (INN) Testosterone Testosterone

Treatment of Hepatorenal Syndrome

Androgel

Treatment of weight loss in AIDS patients with HIVassociated physiologic testosterone replacement in For use as wasting.

TheraDerm Testosterone Transdermal System weight loss.

androgen deficient HIV+ patients with an associated

Testosterone propionate ointment 2%

Treatment of vulvar dystrophies. Treatment of constitutional delay of growth and puberty in boys.

Testosterone sublingual

Tetrabenazine

Xenazine

Treatment of Huntington's disease.

Tetrabenazine

Treatment of moderate/severe tardive dyskinesia.

Tetrahydrobiopterin Tetraiodothyroacetic acid

Phenoptin

Treatment of of thyroid stimulating hormone in Suppression hyperphenylalaninemia patients with well-differentiated cancer of the thyroid gland. Treatment of adenocarcinoma of the esophagus and stomach

Tezacitabine TGF(beta)2-specific phosphorothioate antisense oligodeoxynucleotide

Oncomun

Treatment of malignant glioma

TGp1PTH1-34

Treatment of solitary (unicameral) bone cysts.

Thalidomide Thalidomide

Thalomid

Treatment of Myelodysplasticrecurrent aphthous Treatment and prevention of Syndrome ulcers in severely, terminally immunocompromised patients.

Thalidomide

Synovir

Treatment of HIV-associated wasting syndrome.

Thalidomide Thalidomide Thalidomide

Thalomid

Treatment of Crohn's disease. Prevention of graft versus host disease in patients receiving bone marrow transplantation. Treatment of graft versus host disease in patients receiving bone marrow transplantation. Treatment and maintenance of reactional lepromatous leprosy. Treatment of the clinical manifestations of mycobacterial infection caused by Mycobacterium tuberculosis and non-tuberculous mycobacteria.

Thalidomide

Thalidomide

Thalidomide

Prevention of graft versus host disease.

Thalidomide

Treatment of graft versus host disease.

Thalidomide Thalidomide

Treatment of primary brain malignancies. Treatment of severe recurrent aphthous stomatitis in severely, terminally immunocompromised patients.

Thalidomide

Thalomid

Treatment of erythema nodosum leprosum.

Thalidomide

Treatment of Kaposi's sarcoma.

Thalidomide Thiotepa

Thalomid Tepadina

Treatment of multiple myeloma Conditioning treatment prior to hematopoietic stem cell transplantation Treatment of stage IIb through Stage IV malignant melanoma

Thymalfasin

Zadaxin

Thymalfasin

Zadaxin

Treatment of chronic active hepatitis B.

Thymalfasin

Zadaxin

Treatment of DiGeorge anomaly with immune defects.

Thymalfasin

Zadaxin

Treatment of hepatocellular carcinoma.

Thymosin beta 4

Thymoxamine HCl Thyrotropin alfa

Treatment of epidermolysis bullosa Reversal of phenylephrine-induced mydriasis in patients who have narrow anterior angles and are at risk of developing an acute attack of angle-closure glaucoma following mydriasis.

Thyrogen

Treatment of well-differentiated papillary, follicular or combined papillary/follicular carcinomas of the thyroid

Thyrotropin alpha

Thyrogen

As an adjunct in the diagnosis of thyroid cancer.

Tiapride Tiazofurin (2-Beta-D-ribofuranosyl-4thiazolecarboxamide)

Treatment of Tourette's syndrome.

Chronic myelogenous leukemia (CML)

Tilarginine acetate

Treatment of cardiogenic shock Prevention of access graft disease in hemodialysis patients

tin ethyl etiopurpurin

tinidazole

Tindamax

Treatment of giardiasis

Tinidazole Tiopronin

Tindamax Thiola

Treatment of amebiasis Prevention of cystine nephrolithiasis in patients with homozygous cystinuria.

Tipifarnib

Zarnestra

Treatment of acute myeloid leukemia

tirapazamine

Tiratricol Tissue repair cells obtained from autologous bone marrow expanded ex vivo with a cell production system Tissue repair cells obtained from autologous bone marrow expanded ex vivo with a cell production system

Triacana

Treatment of head and neck cancer For use in combination with levo-thyroxine to suppress thyroid stimulating hormone in patients with well-differentiated thyroid cancer who are intolerant to adequate doses of levo-thyroxine alone.

Treatment of osteonecrosis

Treatment of dilated cardiomyopathy For the secondary prevention (prevention of lesional induction) of disorders with UV-A and visible lightinduced photosensitivity, specifically Actinic prurigo, Hydroa vacciniforme, Solar urticara (SU), Chronic Actinic Dermatitis (CAD), the cutaneous prop

Titanium dioxide and bisoctrizole Tizanidine HCl Tobramycin

Zanaflex Tobi

Treatment of spasticity associated with multiple sclerosis and spinal cord injury. Treatment of bronchiectasis patients infected with Pseudomonas aeruginosa.

Tobramycin for inhalation Tocophersolan oral solution (vitamin E-tpgs)

TOBI

Treatment of bronchopulmonary infections of Pseudomonas aeruginosa in cystic fibrosis patients. Treatment of vitamin E deficiency resulting from malabsorption due to prolonged cholestatic hepatobiliary disease.

Topiramate

Topamax

Treatment of Lennox-Gastaut syndrome.

toralizumab

Treatment of immune thrombocytopenic purpura

Toremifene

Treatment of desmoid tumors. Hormonal therapy of metastatic carcinoma of the breast.

Toremifene

Fareston

Tositumomab and iodine I 131 tositumomab

Bexxar

Treatment of non-Hodgkin's B-cell lymphoma.

trabectedin

Yondelis

Treatment of soft tissue sarcoma.

trabectedin

Yondelis

Treatment of patients with epithelial ovarian cancer

Tramadol hydrochloride

Management of postherpetic neuralgia

Tramadol hydrochloride Tranexamic acid

Cyklokapron

Treatment of painful HIV-associated neuropathy Treatment of patients with congenital coagulopathies who are undergoing surgical procedures (e.g. dental extractions). Treatment of patients undergoing prostatectomy where there is hemorrhage or risk of hemorrhage as a result of increased fibrinolysis or fibrinogenolysis.

Tranexamic acid

Cyklokapron

Tranexamic acid

Cyklokapron

Treatment of hereditary angioneurotic edema.

Tranilast

Rizaben

For the treatment of maligant glioma

Transforming growth factor-beta 2 Transgenic human alpha 1 antitrypsin Trastuzumab

Treatment of full thickness macular holes. Treatment of emphysema secondary to alpha 1 antitrypsin deficiency.

Herceptin

Treatment of patients with pancreatic cancer that overexpress p185HER2.

Treosulfan

Ovastat

Treatment of ovarian cancer.

treprostinil

Remodulin

Treatment of pulmonary arterial hypertension.

Tretinoin

Vesanoid

Treatment of acute promyelocytic leukemia.

Tretinoin

ATRA-IV

Treatment of acute and chronic leukemia.

Tretinoin

ATRA-IV

Treatment of T-cell non-Hodgkin's lymphoma Treatment of squamous metaplasia of the ocular surface epithelia (conjunctiva and/or cornea) with mucous deficiency and keratinization.

Tretinoin tri-antennary glycotripeptide derivative of 5fluorodeoxyuridine monophosphate Trientine HCl

Syprine

Treatment for hepatocellular carcinoma Treatment of patients with Wilson's disease who are intolerant, or inadequately responsive to penicillamine.

Triheptanoin

Triheptanoim-SASOl Specialfatty acid disorders Treatment of Oil

Trimetrexate Trimetrexate glucuronate

Neutrexin

Treatment of metastatic osteogenic sarcoma. Treatment of patients with advanced non-small cell carcinoma of the lung.

Trimetrexate glucuronate

Neutrexin

Treatment of Pneumocystis carinii pneumonia in AIDS patients.

Trimetrexate glucuronate

Treatment of pancreatic adenocarcinoma.

Trimetrexate glucuronate Trimetrexate glucuronate Triptorelin pamoate

Treatment of metastatic colorectal adenocarcinoma. Treatment of metastatic carcinoma of the head and neck (i.e. buccal cavity, pharynx, and larynx).

Decapeptyl Injection ovarian carcinoma of epithelial origin.

For use in the palliative treatment of advanced Treatment of moderate to severe clinical forms of hemolytic disease of the newborn arising from placental transfer of antibodies against blood group substances A and B. Prevention of ABO medical hemolytic reactions arising from ABO-incompatible bone marrow transplantation. Treatment of moderate to very severe clinical forms of transfusion reactions arising from ABO incompatible transfusions of blood, blood products, and blood derivatives. For use in ABO-incompatible solid organ transplantation, including kidney, heart, liver and pancreas.

Trisaccharides A and B Trisaccharides A and B

Biosynject Biosynject

Trisaccharides A and B Trisaccharides A and B

Biosynject

Trisodium citrate concentration Trisodium zinc Diethylenetriaminepentaacetate

Hemocitrate

For use in leukapheresis procedures. Treatment of patients with known or suspected internal contamination with plutonium, americium, or curium to increase the rate of elimination.

Troxacitabine Trypan blue Tumor necrosis factor-binding protein 1 Tumor necrosis factor-binding protein II

Troxatyl

Treatment of acute myeloid leukemia Selectively staining epiretinal membranes during including all patients with CD4 counts less than 200 cells per mm3. Treatment of symptomatic patients with the AIDS including all patients with CD4 T-cell counts less than 200 cells per mm3.

MembraneBlue ophthalmicof symptomatic patients with AIDS Treatment surgical victrectomy procedures

Tyloxapol

Supervent

Treatment of cystic fibrosis.

tyrosine kinase inhibitor

Treatment of mastocytosis

Ubiquinol

Ubi-Q-Nol, Li-Q-Nol Treatment of Huntington's Disease

Ubiquinol, coenzyme Q10, ubiquinone

UBI-Q-NOL

Treatment of pediatric congestive heart failure

Ubiquinone Unconjugated Chimeric (human-murine) G250 IgG monoclonal antibody

Ubi-Q-Gel

Treatment of mitochondrial cytopathies.

Treatment of renal cell carcinoma.

Urea for intravitreal injection Uridine 5'-triphosphate

Neurosolve

Treatment of retinitis pigmentosa To facilitate the removal of lung secretions in the treatment of patients with primary ciliary dyskinesia.

Uridine 5'-triphosphate

Urofollitropin

Metrodin

Urofollitropin Urogastrone Ursodiol

Fertinex

Treatment of cystic fibrosis. For induction of ovulation in patients with polycystic ovarian disease who have an elevated LH/FSH ratio and who have failed to respond to adequate clomiphene citrate therapy. For the initiation and re-initiation of spermatogenesis in adult males with reproductive failure due to hypothalamic or pituitary dysfunction, hypogonadotropic hypogonadism. regeneration and For acceleration of corneal epithelial healing of stromal incisions from corneal transplant surgery.

Actigall

Management of the clinical signs and symptoms associated with primary biliary cirrhosis.

Ursodiol

URSO

Treatment of patients with primary biliary cirrhosis.

Vaccinia Immune Globulin (Human) Intravenous

CNJ-016

Treatment of complications of vaccinia vaccination

Vaccinia Immune Globulin (Human) Intravenous

Treatment of severe complications from the smallpox vaccine

Valine, isoleucine and leucine valine-valine-ganciclovir

VIL

Treatment of hyperphenylalaninemia. Treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HSV1 and HSV2.

Valproic acid, sodium

PEAC

Treatment of familial adenomatous polyposis

Valrubicin

Valstar

Vandetanib

Zactima

Treatment of carcinoma in situ of the urinary bladder. Treatment of patients with follicular thyroid carcinoma, medullary thyroid carcinoma, anaplastic thyroid carcinoma, and locally advanced and metastatic papillary thyroid carcinoma

Vapreotide vapreotide

Sanvar Sanvar

Treatment of symptomatic carcinoid tumors Treatment of esophageal variceal hemorrhage patients with portal hypertension.

vapreotide vapreotide

Octastatin Octastatin

Treatment of gastrointestinal and pancreatic fistulas. Prevention of early postoperative complications following pancreatic resection.

vapreotide Varicella Zoster Immune Globulin (Human)

Sanvar VariZIG

For the treatment of acromegaly Passive immunization for the treatment of exposed, susceptible individuals who are at risk of complications from varicella

Vasoactive intestinal peptide

Treatment of Acute Respiratory Distress Syndrome.

Vasoactive Intestinal Peptide

Treatment of pulmonary arterial hypertension

Vasoactive intestinal polypeptide

Treatment of acute esophageal food impaction. Debridement of severe, deep dermal burns in hospitalized patients

Vibriolysin

Vibrilase

vigabatrin

Sabril

Treatment of infantile spasms.

Viloxazine HCl

Catatrol

Treatment of narcolepsy.

Viloxazine HCl

Catatrol

Treatment of cataplexy.

vincristine sulfate liposome injection

Marqibo

Treatment of acute lymphoblastic leukemia.

Virulizin

Virulizin

Treatment of pancreatic cancer.

viscous budesonide

Treatment for pediatric eosinophilic esophagitis.

vorinostat

Treatment of multiple myeloma

vorinostat

Zolinza

Treatment of T-cell non-Hodgkin's lymphoma

vorinostat

Treatment of mesothelioma

Xenogeneic hepatocytes

HepatAssist Liver Assist System liver failure. Treatment of severe

Yttrium (90Y) antiferritin polyclonal antibodies Ferritarg P Yttrium-90 radiolabeled humanized monoclonal anti-carcinoembroyonic antigen IgG antibody

Treatment of Hodgkin's disease.

Cea-Cide

Treatment of ovarian carcinoma.

Zalcitabine

Hivid

Treatment of AIDS.

Zalcitabine

Treatment of AIDS.

Zidovudine

Retrovir

Treatment of AIDS.

Zidovudine

Retrovir

Treatment of AIDS related complex.

Zinc acetate

Galzin

Treatment of Wilson's disease.

Zoledronate

Zometa, Zabel Treatment of tumor induced hypercalcemia.

Zosuquidar trihydrochloride

Treatment of acute myeloid leukemia

total designated products: 1749
Indication Approved for Marketing Designation Date Sponsor
2/16/2006
PharmAthene, Inc.

3/31/2003

Intarcia Therapeutics, Inc.

1/10/2005

Tibotec, Inc.

8/10/2004

BioCryst Pharmaceuticals, Inc.

8/13/2004

BioCryst Pharmaceuticals, Inc.

1/29/2004 1/10/2005

BioCryst Pharmaceuticals, Inc. Fujisawa Healthcare, Inc.

9/1/2004 1/10/2005

PTC Therapeutics PTC Therapeutics, Inc.

7/5/2007

Global Alliance for TB Drug Development

8/19/2003

Pfizer Global Research and Development

11/29/2002 8/13/2004

Novartis Pharmaceuticals Corporation Adventrx Pharmaceuticals, Inc.

12/8/2004

Inotek Pharmaceuticals Corporation

7/12/2007 10/3/2001 7/3/2003

Otsuka Pharmaceutical Company, Ltd Phase 2 Discovery, Inc. Phase 2 Discovery, Inc.

3/28/2006

Auris Medical, Inc.

11/4/2003

Aeolus Pharmaceuticals, Inc.

7/10/2003

Genzyme Corporation

10/21/2004

Vion Pharmaceuticals, Inc.

5/12/1998

Oxford GlycoSciences

6/10/1999

Louisiana State University Medical Center Foundation

2/10/1999

NeoRx Corporation

1/25/2007

Adeza Biomedical

9/9/2004

Kosan Biosciences, Inc

9/3/2004

Kosan Biosciences, Inc.

2/25/2004

Amicus Therapeutics, Inc.

6/18/2007

Amicus Therapeutics, Inc

5/23/2006

FoldRx Pharmaceuticals, Inc.

12/2/2003

Callisto Pharmaceuticals, Inc.

9/18/2006

Callisto Pharmaceuticals, Inc.

1/13/2003

Repligen Corporation

8/15/2003

Inologic, Inc.

9/17/1993

Kennedy & Hoidal, M.D.'s

12/10/2004

Rexahn Corporation

12/8/2004

Rexahn Corporation

12/8/2004

Rexahn Corporation

12/1/2004

Rexahn Corporation

12/1/2004

Rexahn Corporation

7/21/1987

National Cancer Institute, Dct

2/27/1987

Lemmon Company

8/3/2001

Lawrence Panasci, MD

11/15/2001 9/9/1996

Pangene Corporation Grant, Steven M.D.

4/11/2005

PR Pharmaceuticals, Inc.

4/4/2005

EntreMed, Inc.

6/16/2006

EntreMed, Inc.

7/10/2001

EntreMed, Inc.

11/18/2005

Prosena B.V.

3/23/2000

Sugen, Inc.

9/11/1998

Sugen, Inc.

12/18/1990 9/20/2000

Jacobus Pharmaceutical Company Elliot Danforth, Jr., M.D.

11/20/1989 10/11/2006

Berlex Laboratories, Inc. Dynogen Pharmaceuticals, Inc.

12/12/2005

A. Carlsson Research AB

4/10/2003

Kiadis Pharma Canada, Inc.

12/21/1998

Biomedical Frontiers, Inc.

8/22/2007 12/14/2005 4/26/2006 12/13/1989

Metabasis Therapeutics, Incorporated Neurorecovery, Inc. Jacobus Pharmaceutical Co., Inc. Beeken, Warren M.D.

12/1/2005

Trophos SA

7/20/2006

Johnson & Johnson Pharmaceutical Research & Dev,

12/27/2006

SIGA Technologies, Inc.

12/18/2006

SIGA Technologies, Inc.

6/15/2007

ClinTec International Ltd.

10/11/2006

Reata Pharmaceuticals, Inc.

8/20/2003

Now Pharm AG

5/11/1992

ILEX Oncology, Inc.

6/18/2007

Humanetics, Inc.

9/2/1999 12/20/1993

GlaxoSmithKline Biogen, Inc.

8/3/1987

SuperGen, Inc.

5/26/2006

Xechem International, Inc.

5/26/2006

Hana Biosciences, Inc.

3/5/2004

InterMune, Inc.

2/6/2006

Cornerstone Pharmaceuticals, Inc.

4/6/1999

MGI Pharma, Inc.

3/24/1997 6/22/1993

SciClone Pharmaceuticals, Inc. Therakos, Inc.

5/12/1994

Therakos, Inc.

1/29/2004 1/2/1997

Immunomedics, Inc. Allergan, Inc.

9/16/1996
Treatment of pediatric HIVinfection/AIDS patients

SuperGen, Inc.

5/15/2001

NovoMed Pharmaceuticals, Inc.

1/15/2003

Celgene Corporation

9/3/2004

Burzynski Research Institute, Inc.

7/28/2000

La Jolla Pharmaceutical Co.

11/25/2003 For the use of Acetadote(registered TM) Injection, administered 8/13/1987 intravenously within 8 to 10 hours after ingestion of a potentially heptotoxic quantity of acetaminophen, to prevent or 10/19/2001 lessen hepatic injur

Menarini Ricerche S.p.A. Bristol-Myers Squibb Company

Cumberland Pharmaceuticals, Inc.

8/3/2000

Genzyme Corporation

6/20/1988

Lincoln Diagnostics

10/19/2006

Abbott Laboratories

3/21/2005

Abbott Laboratories

5/21/2007 6/13/2001

Amsterdam Molecular Therapeutics BV Avigen, Inc.

6/13/2001

Avigen, Inc.

3/20/2007

Applied Genetic Technologies Corporation

5/21/2007

Applied Genetic Technologies Corporation

2/15/1995

Targeted Genetics Corporation

8/1/1989

Medco Research, Inc.

6/17/2005

Advantagene, Inc.

12/15/1999

GenStar Therapeutics Corporation

7/31/2001

Ark Therapeutics Ltd

1/3/1989

Pediatric Pharmaceuticals, Inc.

1/21/2003

Large Scale Biology Corporation

2/6/2006

TolerRX, Inc.

10/8/1992
Treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia Treatment of cystic hydatid 1/18/1996 solium. disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, 1/17/1996 Echinococcus granulosus.

AutoImmune, Inc.

SmithKline Beecham Pharmaceuticals

SmithKline Beecham Pharmaceuticals

3/12/2002 3/22/1989
Treatment of adults (>18 years old) with metastatic renal cell carcinoma.

MotoGen, Inc. Chiron Corporation

9/14/1988

Chiron Corporation

Treatment of adults with metastatic melanoma.

9/10/1996

Chiron Corporation

11/24/1998

Chiron Corporation

The treatment of patients with Bcell chronic lymphocytic leukemia who have been treated with alkylating agents and who have failed fludarabine therapy. 10/20/1997

Genzyme Corporation Merck & Co., Inc.

3/31/2003

2/13/2001

Richard J. Wenstrup, M.D.

7/8/2005

Cinergen, LLC

8/9/2005 7/21/1995
Long-term enzyme replacement therapy for children, adolescents and adult patients with a confirmed diagnosis of Type I Gaucher disease who exhibit signs and symptoms that are severe enough to result in one or more of the following conditions: 3/11/1985 a) moderateTopical treatment of cutaneous lesions in patients with AIDS3/24/1998 related Kaposi's sarcoma.

Cinergen, LLC Genzyme Corporation

Genzyme Corporation Eisai Medical Research, Inc

4/10/1992 11/21/2002

Ligand Pharmaceuticals, Inc. Alwyn Company, Inc.

7/18/1997

Bayer Healthcare Pharmaceuticals, Inc.

6/13/1997

Applied Immunotherapeutics, LLC

9/1/2004

Neurotech USA, Inc.

1/28/2005

MolMed S.p.A.

12/4/1985
Management of patients with leukemia, lymphoma, and solid 12/4/1985 tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels and who 10/16/1992 cannot tolerate oral therapy.

Burroughs Wellcome Company

Burroughs Wellcome Company

Catalytica Pharmaceuticals, Inc

11/9/1987

Burroughs Wellcome Company

3/5/2004

Bio Products Laboratory

3/17/2004 1/1/1984 12/22/2004

Bio Products Laboratory Chiron Corporation Kamada Ltd.

9/1/2004
For chronic replacement therapy of individuals having congenital 11/24/1999 deficiency of alpha1- proteinase inhibitor with clinically demonstrable panacinar 12/7/1984 emphysema.

Kamada Ltd. Aventis Behring L.L.C.

Bayer Corporation

7/20/1990

Desnick, Robert J. M.D.

6/17/1991 6/22/1998 8/19/1997

David Calhoun, Ph.D. Shire Human Genetic Therapies, Inc. National Institute of Diabetes, and Digestive and Kidney Diseases

3/28/2006

Penwest Pharmaceuticals Company

10/20/1993
Single agent palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent based combination. Treatment of pulmonary arterial hypertension (WHO group I) in patients with WHO class II or III symptoms to improve exercise capacity and delay clinical worsening

Schwarz Pharma, Inc. Daniel F. Hanley, MD

1/27/2003

2/9/1984 4/13/2007

Medimmune Oncology, Inc. Sanofi-Aventis US, Inc.

7/16/2004

Gilead Colorado

3/27/2003

Amgen, Inc.

10/4/1999
To reduce the cumulative renal toxicity associated with repeated 5/30/1990 administration of cisplatin in patients with advanced ovarian 5/30/1990 cancer.

Medimmune Oncology, Inc. Medimmune Oncology, Inc. Medimmune Oncology, Inc. Medimmune Oncology, Inc.

5/30/1990

Reduction of the incidence of moderate to severe xerostomia in patients undergoing postoperative radiation treatment for head and neck cancer, where the radiation port includes a substantial portion of the parotid 5/12/1998 glands.

Medimmune Oncology, Inc. Medimmune Oncology, Inc. Transave, Inc.

11/24/1998 3/9/2006

7/18/1990

Glaxo Wellcome Research and Development

1/6/1995

Eastern Virginia Medical School

3/20/2007

DUSA Pharmaceuticals, Inc.

4/6/1993

Syncom Pharmaceuticals, Inc.

Treatment of tuberculosis

2/19/1992

Jacobus Pharmaceutical Company

3/29/2005

The Institute for One World Health

9/9/1994

Kanyok, Thomas P. Pharm.D.

5/14/1993

Kanyok, Thomas P. Pharm.D.

11/15/1993
For initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy.

Kanyok, Thomas P. Pharm.D.

8/17/1993

Academic Pharmaceuticals, Inc.

3/16/1994

Wyeth-Ayerst Laboratories

1/31/1994

Pipex Pharmaceuticals, Inc.

12/20/2006

Xanthus Pharmaceuticals, Inc.

12/15/2005

Nektar Therapeutics

8/21/1996

The Liposome Company, Inc.

9/23/1996

The Liposome Company, Inc.

5/6/1996

The Liposome Company, Inc.

5/6/1996
Treatment of invasive fungal infections in patients who are refractory to or intolerant of conventional amphotericin B therapy.

The Liposome Company, Inc.

6/27/1996

The Liposome Company, Inc.

12/5/1991

Liposome Company, Inc.

12/7/1984

Warner-Lambert Company

12/18/2006
Treatment of patients with essential thrombocythemia to 7/14/1986 reduce the elevated platelet count and the risk of thrombosis and to ameliorate associated 1/27/1988 symptoms.

Akorn, Inc.

Roberts Pharmaceutical Corp.

Roberts Pharmaceutical Corp.

6/11/1985

Roberts Pharmaceutical Corp.

1/21/1992

Genzyme Corporation

8/27/1992 4/10/1992

Scios, Inc. Scios, Inc.

4/15/2005 10/20/1989

Xytis, Inc. Knoll Pharmaceutical Company

8/3/2001 2/16/2000 1/29/1986 1/29/1986

Maret Pharmaceutical Corporation Maret Pharmaceuticals Xoma Corporation Xoma Corporation

10/16/2002

AEterna Zentaris, Inc.

2/12/2003

Biogen IDEC, Inc.

10/6/2005

Seattle Genetics, Inc.

9/10/1990

Baxter Healthcare Corporation

5/21/2003 5/2/1990 5/2/1990 5/3/1990 5/3/1990

Xenova Biomedix Limited Biomedical Research Institute Biomedical Research Institute Biomedical Research Institute Biomedical Research Institute

9/18/2006 For surgical and/or invasive procedures in patients with von Willebrand Disease (VWD) in 3/23/1989 whom desmopressin is either ineffective or contraindicated. It is not indicated for patients with severe VWD (Type 3) 1/5/1996 undergoing major surgery

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Toxoplasmosis, as adjunctive with pyrimethamine

Bock Pharmacal Company Fuisz Technologies, Ltd. Darby Pharmaceuticals, Inc. Darby Pharmaceuticals, Inc.

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Eon Labs Manufacturing, Inc.

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Treatment and prevention of 5/6/1997 respiratory failure due to pulmonary surfactant deficiency 6/7/1985 in preterm infants.

Bio-Technology General Corp.

Warner-Lambert Company ONY, Inc.

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Synsorb Biotech Inc. Repligen Corporation ChiRhoClin, Inc. ChiRhoClin, Inc. ChiRhoClin, Inc.

For use in secretin stimulation testing for: Stimulation of pancreatic secretions to facilitate the identification of the ampulla of Vater and accessory papilla during endoscopic retrograde Use in secretin stimulation cholangio-pancreatography testing for stimulation of (ERCP) pancreatic secretions, including bicarbonate, to aid in the diagnosis of pancreatic exocrine Use in secretin stimulation dysfunction testing for stimulation of gastrin

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Prophylaxis of organ rejection in patients receiving allogenic 6/6/2005 heart transplants.

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Tap Holdings Inc.

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Belpharma N.V.

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Schering-Plough Reasearch Institute

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Treatment of adult patients with refractory anaplastic 10/14/1998 astrocytoma, i.e., patients at first relapse who have experienced disease progression on a drug regimen containing a 10/5/1998 nitrosourea and procarbazine.

Schering-Plough Research Institute

Schering-Plough Research Institute

Schering-Plough Research Institute

Treatment of advanced renal Induction therapy in patients cell carcinoma with refractory childhood acute lymphoblastic leukemia when used in combination with other approved anticancer agents.

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Wyeth Pharmaceuticals, Inc.

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Bristol-Myers Squibb Pharmaceutical Research Institute

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Rhone-Poulenc Rorer Pharmaceuticals, Inc.

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Orphan Therapeutics, LLC Unimed Pharmaceuticals, Inc. Watson Laboratories

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2/27/1998 Acute treatment of the cutaneous manifestations of moderate to severe erythema 5/1/1995 nodosum leprosum (ENL) and as maintenance therapy for prevention and suppression of the cutaneous manifestations of 7/26/1995 ENL recurrences.

Celgene Corporation Celgene Corporation

Celgene Corporation

7/29/1998
Treatment of patients with newly 10/14/1998 diagnosed multiple myeloma

Celgene Corporation

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SciClone Pharmaceuticals, Inc.

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As an adjunctive diagnostic tool for serum thyroglobulin (Tg) 8/3/2001 testing with or without radioiodine imaging in the follow-up of patients with thyroid 2/24/1992 cancer.

Iolab Pharmaceuticals Genzyme Corporation

Genzyme Corporation

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Sanofi-Synthelabo, Inc.

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Valeant Research & Development

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Arginox Pharmceuticals, Inc.

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Treatment of giardiasis caused by G. duodenalis (also termed Treatment in both adults G. lamblia)of intestinal and amebiasis and amebic than pediatric patients older liver abcess caused by three years of age E. histolytica 4/18/2002 in both adults and pediatric patients older than three years of age. It is not indicated for the treatment of asymptomatic cyst 8/20/2003 passage.

Presutti Laboratories, Inc.

Presutti Laboratories, Inc. Pak, Charles Y.C. M.D.

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7/6/2004

Johnson & Johnson Pharmaceutical Research & Dev.

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Laphal Laboratoires

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Aastrom Biosciences, Inc.

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For the acute and intermittent management of increased muscle tone associated with spasticity.

5/25/2005 1/31/1994 6/18/1999

Orfagen Athena Neurosciences, Inc. Novartis Pharmaceuticals Corp.

Management of cystic fibrosis patients with P.aeruginosa.

10/13/1994 4/15/1988

Novartis Pharmaceuticals Corp Sterling Winthrop

As adjunctive therapy in patients two years and older with siezures associated with 11/25/1992 Lennox-Gastaut syndrome.

Johnson & Johnson Pharmaceutical R & D, LLC

3/14/2002

Biogen IDEC Inc.

Treatment of metastatic breast Treatment of patients with CD20 cancer in postmenopausal positive, follicular, nonwomen with estrogen positive or Hodgkin's lymphoma, with and 9/19/1991 receptor unknown tumors. without transformation, whose disease is refractory to Rituximab and has relapsed 5/16/1994 following chemotherapy

8/17/1993

Orion Corporation

Orion Corporation

GlaxoSmithKline

9/30/2004

Johnson & Johnson Pharmaceutical Research & Dev.

3/29/2005

Johnson & Johnson Pharmaceutical Research & Dev.

4/26/2005

TheraQuest Biosciences, LLC

1/28/2005 10/29/1985

TheraQuest Biosciences, LLC Pharmacia Inc.

7/23/1987

Pharmacia Inc.

9/9/1985

Pharmacia Inc.

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Angiogen Pharmaceuticals, Pty. Ltd.

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Celtrix Pharmaceuticals, Inc. PPL Therapeutics (Scotland) Limited Genentech, Inc.

5/16/1994
Induction of remission in arterial Treatment of pulmonary patients with acute 6/4/1997 hypertension. promyelocytic leukemia who are refractory to or unable to tolerate anthracycline based cytotoxic 10/24/1990 chemotherapeutic regimens.

Medac GmbH

United Therapeutics Corp.

Hoffmann-La Roche, Inc.

1/14/1993

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Hannan Ophthalmic Marketing Services, Inc

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Cell Works Inc. Merck Sharp & Dohme Research

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Baylor Research Institute

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Medimmune Oncology, Inc. Medimmune Oncology, Inc.

Concurrent leucovorin administration as an alternative therapy for the treatment of moderate to severe PCP in immunocompromised patients who are intolerant of, or are refractory to, trimethoprim sulfamethoxazole.

5/15/1986

Medimmune Oncology, Inc.

7/25/1985

Medimmune Oncology, Inc.

7/25/1985 7/25/1985 8/10/1990

Medimmune Oncology, Inc. Medimmune Oncology, Inc. Debio R.A. Inc.

4/12/1987 4/15/1988

Chembiomed, Ltd. Chembiomed, Ltd.

8/3/1987 4/20/1987

Chembiomed, Ltd. Chembiomed, Ltd.

6/15/1995

Hemotec Medical Products, Inc.

2/27/2004

CustomCare Pharmacy

4/4/2005 8/2/2006 1/6/1993 1/6/1993

Structural GenomiX, Inc. (SGX) Dutch Ophthalmic Research Center Int'l BV Serono Laboratories, Inc. Serono Laboratories, Inc.

3/8/1995

Kennedy & Hoidal, M.D.'s

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AB Science

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Gel-Tec

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Gel-Tec, Division of TISHCON Corporation

12/14/1999

Gel-Tec, Division of Tishcon Corp.

3/22/2001

Wilex Biotechnology GmbH

12/14/2005 6/26/1996

Vitreo Retinal Techologies, Inc Inspire Pharmaceuticals, Inc.

12/4/1995

Inspire Pharmaceuticals, Inc.

11/25/1987

Serono Laboratories, Inc.

12/5/1997 11/1/1984 2/19/1991

Serono Laboratories, Inc. Chiron Vision Novartis Pharmaceuticals Corporation

6/20/1991

Axcan Pharma Inc.

treatment and/or modification of the following conditions, which are complications resulting from smallpox vaccination: Eczema vaccinatum Progressive vaccinia Severe generalized vaccinia Vaccinia infections in individuals who have skin conditions such 6/18/2004 as Treatment and modification of aberrant infections induced by vaccinia virus that include its accidental implantation in eyes (except in cases of isolated keratitis), mouth, or other areas where vaccinia infection would constitute a special hazard; 6/18/2004 eczema

Cangene Corporation

DynPort Vaccine Company LLC

1/5/1996 5/21/2007
For intravesical therapy of BCGrefractory carcinoma in situ of the urinary bladder in patients 6/24/2005 for whom immediate cystectomy would be associated with unacceptable morbidity or 5/23/1994 mortality.

Leas Research Products Verenta Pharmaceuticals, Inc.

Topo Target Germany AG

Anthra Pharmaceuticals, Inc.

10/21/2005

AstraZeneca Pharmaceutical LP

4/6/2004 1/10/2000

H3 Pharma, Inc. Debiovision, Inc.

1/10/2000 3/6/2000

Debiopharm S.A. Debiopharm S.A.

11/4/2003 11/7/2006

H3 Pharma, Inc. Cangene Corporation

3/9/2001

Biogen Idec MA, Inc.

2/22/2005

Biogen Idec MA, Inc.

6/23/1993

Research Triangle Pharmaceuticals

6/16/2006

BioMarin Pharmaceutical Inc.

6/12/2000

Ovation Pharmaceuticals, Inc.

6/11/1984

Stuart Pharmaceuticals

6/11/1984

Stuart Pharmaceuticals

1/8/2007

Hana Biosciences, Inc.

2/1/2001

Lorus Therapeutics Inc.

12/20/2006
Treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma (CTCL) who have progressive, persistant or recurrent disease on or following two systemic therapies.

University of California San Diego Medical Center

6/12/2003

Merck Research Laboratories

3/16/2004

Merck & Co., Inc.

3/17/2004

Merck & Co., Inc.

11/27/1998

Circe Biomedical, Inc.

9/18/2006

MAT Biopharma

8/3/1999

Immunomedics, Inc.

Combination therapy with zidovudine is indicated for the treatment of adult patients with advanced HIV infection (CD4 count < 300) who have demonstrated malignant clinical 6/28/1988 or immunologic deterioration.

Hoffmann-La Roche, Inc.

12/9/1986

National Cancer Institute, DCT

7/17/1985

Glaxo Wellcome Inc.

For maintenance treatment of patients with Wilson's disease who have been initially treated with a chelating agent.

5/12/1987

Glaxo Wellcome Inc.

11/6/1985

Lemmon Company

Treatment of hypercalcemia of malignancy.

8/18/2000

Novartis Pharmaceuticals Corp.

12/15/2005

Kanisa Pharmaceuticals, Inc.

Sponsor Address
One Park Place

Text4
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Text34
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2000 Powell Street

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Emeryville CA 94608

1020 Stony Hill Road

Yardley PA 19067

2190 Parkway Lake Drive

Birmingham AL 35244

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2190 Parkway Lake Drive Three Parkway North

Birmingham AL 35244 Deerfield IL 60015-2548

100 Corporate Court 100 Corporate Court

South Plainfield NJ 07080 South Plainfield NJ 07080

80 Broad Street

New York NY 10004

50 Pequot Avenue

New London CT 06320 East Hanover NJ 07936-1080 San Diego CA 92121

One Health Plaza 6725 Mesa Ridge Road

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2440 Research Blvd 3130 Highland Avenue, Third Floor 3130 Highland Ave.

Rockville MD 20850 Cincinnati OH 45219-2374 Third Floor Cincinnati OH 45219

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300 Technology Square

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4560 Horton Street

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33729

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35804

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35202

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39248

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36335

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66 Hanover Road

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Princeton NJ 08540

34515

580 California Street University of Illinois at Chicago College of Pharm

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University Of Illinois At Chicago College of Pharm 833 South Wood Street (m/c886) Rm. 176 Chicago IL 60612 University of Illinois at Chicago College of Pharm

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300 Technology Square

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Princeton NJ 08540

One Research Way

Princeton NJ 08540

One Research Way

Princeton NJ 08540

One Research Way

Princeton NJ 08540

One Research Way

Princeton NJ 08540

One Research Way Parke-Davis Pharmaceutical Research Division

Princeton NJ 08540

35356

2800 Plymouth Road

Ann Arbor MI 48106

2500 Millbrook Drive

Buffalo Grove IL 60089 Eatontown NJ 077242274

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4 Industrial Way West

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Eatontown NJ 07724 Eatontown NJ 077242274

35503

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Cambridge MA 02139

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Elkhart IN 46515

34025

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M9W427

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Lindhagensgatan 133 Pharmaceutical Division, Biological Products 1020 First Ave.

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9312 Old Georgetown Road

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36801

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West Henrietta NY 14586-9728 Swindon SN5 8RU Suite 257 Wiltshire Buffalo Grove IL 60089

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38097

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West Haven CT 06516

34332

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Boston University

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41 Moores Road

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36794

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Seattle WA 98121 Honolulu HI 96826

22322 20th Avenue SE 9200 Indian Creek Parkway 2029 Century Park East 7000 SW 97th Avenue

Suite 150 Building 9, Suite 200 Sixth Floor Miami FL 33173

Bothell WA 98021 Overland Park KS 66210 Los Angeles CA 90067

3 Forbes Rd.

Lexington MA 02421

3 Forbes Rd.

l MA 02421 Princeton NJ 085405308

600 College Road East

CN 5308

La Jolla Laboratories

San Diego CA 92121

2525 28th Street

Boulder CO 80301

38126

787 Seventh Ave., 48th Floor 2025 First Ave.

New York NY 10019 Suite 800 Seattle WA 98121

P. O. Box 970

Pacific Palisades CA 90272

One Executive Drive

P.O. Box 1399

Fort Lee NJ 07024

800 53rd Avenue N.E. 1400 Providence Highway

Minneapolis MN 55432 Norwood MA 02062 Minneapolis MN 55440-9087

33780

800 53rd Avenue N.E.

P.O. 1250

710 Medtronic Parkway NE

Minneapolis MN 55432-5604

1700 Perimeter Park Drive

Morrisville NC 27560

39071

59 Route 10

East Hanover NJ 07936-1080

35927

A Subsidiary of DOR BioPharma, Inc. A Subsidiary of DOR BioPharma, Inc.

850 Bear Tavern Road 850 Bear Tavern Road

Ewing NJ 08628 Ewing NJ 08628

41 Moores Road

Frazer PA 19355

2525 McGaw Avenue

P.O. Box 19791

Irvine CA 92623

32134

8125 N. Hayden Road 677 W. Dekalb Pike 70 Grand Avenue

Scottsdale AZ 85258 King of Prussia PA 19406 River Edge NJ 07661 West Hanford CT 06119-1551

38400

836 Farmington Avenue

Suite 207

625 Cleveland Avenue

Columbus OH 43215

625 Cleveland Avenue

Columbus OH 43215

33420

625 Cleveland Avenue

Columbus OH 43215

33420

68 T.W. Alexander Drive, PO Box 14186 Research Triangle Park NC 27709

Bldg. 337, Paint Branch Drive

College Park MD 20742

Bldg. 337, Paint Branch Drive

College Park MD 20742

3180 Porter Drive

Palo Alto CA 94304 Los Angeles CA 90048 Los Angeles CA 90048

35363

8455 Beverly Blvd.

Suite 308

8455 Beverly Blvd.

Suite 308

1440 Davey Road

Woodridge IL 60517

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way, MS #242

South San Francisco CA 94080-4990

1 DNA Way

South San Francisco CA 94080-4990

55 Challenger Road

Ridgefield Park NJ 07660

36523

Guardwell, Kinsale

County Cork

70 Grand Avenue

Suite 109

River Edge NJ 07661

Suite 235

7200 Hudson Blvd.

Oakdale MN 55128

14 Emmett Place

Whitby, Ontario L1R 2B4

38924

7000 SW 97th Avenue

Miami FL 33173

Ion Channel Advances One MedImmune Way

PO Box 14487 Gaithersburg MD 20878

Durham NC 27709

8 Campus Drive

Parsippany NJ 07054

11199 Sorrento Valley Rd.

San Diego CA 92121-1334

P.O. Box 4000

Princeton NJ 08543

35115

5 Research Parkway

Wallingford CT 06492

40 Landsdowne Street

Canbridge MA 02139

38436

1840 Gateway Dr. 1 Bath Rd., Maidenhead

2nd Floor Berkshire SL6 4UH

San Mateo CA 94404 37215

1 Bath Road

Maidenhead

Berkshire, SL6 4UH

1155 15th Street, N.W., #315 2525 Dupont Drive 1261 Furnace Brook Parkway

Washington DC 20005 P.O. Box 19534 Quincy MA 02169 Irvine CA 92623-9534

2525 Dupont Drive 2525 Dupont Drive 2525 Dupont Drive

P.O. Box 19534 P.O. Box 19534 P.O. Box 19534

Irvine CA 92623-9534 36881 Irvine CA 92713 Irvine CA 92713

32871 32871

800 Gateway Blvd.

South San Francisco CA 94080

36868

27 Maple Street

Milford MA 01757-3650

27 Maple Street

Milford MA 01757-3650

2151 Berkeley Way

Berkeley CA 94704-1011

37917

1030 North Parkview Drive

Bismarck ND 58501

4001 Lexington Avenue North

Arden Hills MN 55126

540 Arapeen Drive, Suite 202

Salt Lake City UT 84108

One Gustave L. Levy Place

New York NY 10029

2525 Dupont Dr.

P.O. Box 19534

Irvine CA 92623-9534

1950 Lake Park Drive 900 Ridgebury Road, Box 368

Smyra GA 30080 Ridgefield CT 06877-0368

225 East Deerpath, Suite 250 610 Lincoln Street

Lake Forest IL 60045 Waltham MA 02451

12419 198th Drive, NE

Woodinville WA 98072

35335

1120 Win Drive

Bethlehem PA 18017

1901 Huguenot Road

Richmond VA 23235

37537

1901 Huguenot Road

Richmond VA 23235

37537

34801 Campus Drive 111 Rock Road

Fremont CA 94555 Horsham PA 19044-2310

36195

4140 Dublin Boulevard 4140 Dublin Blvd

Dublin CA 94568 Suite 200 Dublin CA 94568

Two Annabel Lane, Suite 220 Childrens Hospital of Los Angeles MS 55 Childrens Hospital of Los Angeles

San Ramon CA 94583 Los Angeles CA 90027 4650 Sunset Blvd, MS 55 Los Angeles CA 90027

1550 East Gude Drive 1550 East Gude Drive

Rockville MD 20850 Rockville MD 20850 Research Triangle Pk NC 27709

3030 Cornwallis Road

P.O. Box 12700

236 Old Lancaster Road 5555 Valley Boulevard 1020 First Ave. One Baxter Way

Merion Station PA 19066 Los Angeles CA 90032 PO Box 61501 Westlake Village CA 91362 King of Prussia PA 19406-0901

Hyland Division (Baxter Hyland)

550 North Brand Blvd.

Glendale CA 91203

21823 30th Drive Southeast

Bothell WA 98021

1501 Wakarusa Drive

Lawrence KS 66047

36424

59 Route 10

East Hanover NJ 07936

59 Route 10

East Hanover NJ 07936

31716

60 Columbian Street

P.O. Box 361

Braintree MA 02184

33217

28101 Ballard Road, Suite F 4204 Glencoe Avenue

Lake Forest IL 60045 Marina Del Rey CA 90292

190 Commerce Drive 145 Sakonnet Blvd. 3940 Quebec Avenue North

Warwick RI 02886 Narragansett RI 02882 Minneapolis MN 55427

1576 Sweet Home Road

Amherst NY 14228

146 Medinah Drive

Blue Bell PA 19422-3212

650 Gateway Blvd

South San Francisco CA 94080

981F Industrial Road

San Carlos CA 94070 San Carols CA 94070-4117

San Carlos Business Park

981F Industrial Road

Immeuble "Le Guillaumet" 5 Moore Drive

60, avenue du General de Gaulle Research Triangle Park NC 27709

460 Seaport Court

Suite 220

Redwood CA 94063

102 Tremont Way

Augusta GA 30907

99 Hayden Avenue

Lexington MA 02420-9192

Route 23 & Woodmont Ave., P.O. Box 1510 2910 Seventh Street

King Of Prussia PA 19406 Berkeley CA 94710

216 Bath Road

Slough SL1 4EN Charlestown MA 02129

Merit E. Cudkowicz, MD, MSc

Building 149 13th Street, Room 2274

P.O. Box 376

Ann Arbor MI 48106

7824 Jackson Street

Omaha NE 68114

Amores #1034 Col Del Valle

C.P. 03100 Mexico D.F.

One Kendall Square

Cambridge MA 02139-1562

37735

1440 Davey Road

Woodridge IL 60517

33 ImClone Drive

Branchburg NJ 08876

33 ImClone Drive

Branchburg NJ 08876

38777

Leinenweberstrasse 5

9041 Freiburg, GERMANY

800 South Frederik Avenue, Suite 300

Gaithersburg MD 20877

901 Sawyer Road

Marietta GA 30062

30525

Grillparzerstrasse 10B

81675 Munich

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

7150 Alexander-Fleming

210 Welsh Pool Road

Exton PA 19341

244 Great Valley Parkway 9298 Gaither Road

Malvern PA 19355 Rockville MD 20877

Sharon Wood Technical Center Leinenweberstrasse 5

11370 Reed Hartman Highway Postfach 6529

Cincinnati OH 45241

275, avenue Labrosse Feinberg School of Medicine, Dept. of Gastroentero

Pointe-Claire 676 N. St. Clair St., Suite 1400 Chicago IL 60611

61 Moulton Street

Cambridge MA 02138

8500 Hidden River Pkwy.

Tampa FL 33637

One Technology Place

Rockland MA 02370

777 Old Saw Mill River Road

Tarrytown NY 10591

3200 Walnut Street

Boulder CO 80301

3200 Walnut Street

Boulder CO 80301

One Amgen Center Drive

Thousand Oaks CA 91320-1799

38054

300 Elliott Avenue West

Seattle WA 98119

11 Deer Park Drive

Monmouth Junction NJ 08852-1923

34700 Campus Drive

Fremont CA 94555-3612

34700 Campus Drive P.O. Box 2500

Fremont CA 94555-3612 Smithtown NY 11787

33148

100 Fairway Drive, Suite 134

Vernon Hills IL 60061

920 US Highway 202

P.O. Box 300

Raritan NJ 08869

Route 202, P.O. Box 300

Raritan NJ 08869

34026

1125 Tenton-Harbourton Road

P. O. Box 200

Titusville NJ 08560 Raritan NJ 088690602

920 Route 202

PO Box 300

Route 202 South, P.O. Box 300

Raritan NJ 08869-0602

Gewerbestrasse 16

235 East 42nd Street 7000 Portage Road

150-3-46 Unit 0633-298-113

New York NY 10017 Kalamazoo MI 490010199

3423 Hill Canyon Avenue

Thousand Oaks CA 91360

4545 Horizon Hill Blvd.

San Antonio TX 78229-2263

4545 Horizon Hill Blvd.

San Antonio TX 78229-2263

38349

59 Route 10

East Hanover NJ 07936

31761

340 Kingsland Street

Nutley NJ 07110

PO Box 16532 40 Valley Stream Parkway

Columbus OH 43216-6532 Malvern PA 19335

35340

150 Broadway

Suite 1800

New York NY 10038

480 Arsenal Street

Watertown MA 02472

The Children's Hospital

300 Longwood Avenue, Bader 760

Boston MA 02115

Two Connell Drive 500 Arcola Road, P.O. Box 1200

Berkeley Heights NJ 07922 Collegeville PA 19426

33836

5555 Valley Boulevard

Los Angeles CA 90032

33238

87 Cambridge Park Drive 100 College Road West

Cambridge MA 02140 Princeton NJ 08540

35472 39003

100 College Road West

Princeton NJ 08540

100 College Road West 100 College Road West

Princeton NJ 08540 Princeton NJ 08540

38544 39003

100 College Road West

Princeton NJ 08540

38576

100 College Road West 100 College Road West 100 College Road West 100 Overlook Center

Princeton NJ 08540 Princeton NJ 08540 Princeton NJ 08540 Suite 200 Princeton NJ 085407810

38544

36244

4520 East-West Highway

Third Floor

Bethesda MD 20814

825 Challenger Drive

Green Bay WI 54311

1100 Orthodox Street

Philadelphia PA 19124

1100 Orthodox Street 661 Palisade Ave., P.O. Box 931 5 Moore Drive 5 Moore Drive

Philadelphia PA 19124 Englewood Cliffs NJ 07632 Research Triangle Park NC 27709 Research Triangle Park NC 27709 Research Triangle Park NC 27709

33087 33087

5 Moore Drive

P.O. Box 13398

40 Valley Stream Parkway

Malvern PA 19355

230 Third Avenue 321 Arsenal Street

Waltham MA 02451 Watertown MA 02472

957 Budkingham Avenue

Slough

1824 S. Robertson Blvd. 421 Wakara Way

Los Angeles CA 90035-4317 Salt Lake City UT 84108

14785 Omicron Drive 400 Rella Boulevard, Suite 201

San Antonio TX 78245 Suffern NY 10901

35208

1387 Marina Way South

Richmond CA 94804

4002 Basel

Level 1, 82 Waterloo Road

North Ryde NSW, 2113

228 Hamilton Avenue

Palo Alto CA 94301 San Francisco CA 94104

580 California St.

Suite 1600

755 Jefferson Rd

P.O. Box 1710

Rochester NY 14603

32864

755 Jefferson Rd. 56 Evergreen Drive Division of Pediatric Allergy & Immunology 3525 John Hopkins Court

P.O. Box 1710 Portland ME 04103 Erwin Road San Diego CA 92121

Rochester NY 14603

30958

Durham NC 27710

3525 John Hopkins Court 3525 John Hopkins Court

San Diego CA 92121 San Diego CA 92121

Hoarborside Financial Center

Plaza 10, 14th Floor

Jersey City NJ 07302

950 Tower Lane Tecnology Ventures Corporation Technopolis 950 Tower Lane

Suite 790

Foster City CA 94404 Albuquerque NM 87106 Foster City CA 94404

1155 University Blvd., SE Suite 790

2525 Dupont Drive 2525 Dupont Drive

P.O. Box 19534 P.O. Box 19534

Irvine CA 92623-9534 Irvine CA 92623-9534

Batiment Genavenir IV

F-91058-Evry cedex

Harborside Financial Center

Plaza 10, 14th Floor

Jersey City NJ 07302 Durham NC 277132280 Athens GA 30602

200 Westpark Corporate Center College Of Veterinary Medicine

4364 South Alston Avenue Department of Small Animal Medicine

300 Fairfield Road

Wayne NJ 07470 Ann Arbor MI 481090408

University of Michigan Medical School

300 NIB, 1192 SE

781 Chestnut Ridge Road 800 South Frederick Avenue

P.O. Box 4310 Gaithersburg MD 20877

Morgantown WV 26504

34561

One Mountain Rd.

P.O. Box 9322

Framingham MA 01701-9322

12111 Parklawn Drive One Mountain Road

Rockville MD 20852 P.O. Box 9322 Framingham MA 01701-9322

938 Clopper Road

Gaithersburg MD 20878

10450 Science Center Drive

San Diego CA 92121

36251

Medical University of South Carolina

96 Jonathan Lucas Street, Suite 428 CSB Charleston SC 29425

10390 Pacific Center Court

San Diego CA 92121

10390 Pacific Center Court

San Diego CA 92121

305 South Street Pharmaceutical Division, Biological Products

Boston MA 02130-3597 400 Morgan Lane New Haven CT 06516

36133

340 Kingsland Street

Nutley NJ 07110

35774

P.O. Box 191 37 Cleveland Lane 37 Cleveland Lane

Norwich NY 13815 P.O. Box 5290 P.O. Box 5290 Princeton NJ 08540 Princeton NJ 08540

37 Cleveland Lane

P.O. Box 5290

Princeton NJ 08540

5 Research Parkway

Wallingford CT 06492

38896

5 Research Parkway 650 Cliffside Drive

Wallingford CT 06492 San Dimas CA 91773

38896 35163

Via Pian Scairolo, 6912 Pazzallo

Lugano

3, Azrieli Center

Triangular Tower 45th Floor

6611 Tributary Street

Baltimore MD 21224-6515

6611 Tributary Street

Baltimore MD 21224

6611 Tributary Street

Suite 200

Baltimore MD 21224

6611 Tributary Street 59 Route 10 Apotex Research Inc.

Suite 200 East Hanover NJ 07936-1080 Toronto, Canada M9L 1T9

Baltimore MD 21224

38839 38658

1095 10th Avenue, SE

Minneapolis MN 55414

Piazza XX Settembre, 2

Piazza XX Settembre, 2

22079 Villa Guardia (CO)

Via Belvedere 1 505 Penobscot Drive

Villa Guardia, Italy 22079 Redwood City CA 94063

6111 Royalmount Avenue, Suite 102

Montreal

Quebec H4P 2T4

2401 Foothill Drive

Salt Lake City UT 84109-1405

2401 Foothill Drive

Salt Lake City UT 84109-1405

55 Challenger Road Meridian Center II

Ridgefield Park NJ 07660 Four Industrial Way West Eatontown NJ 077242274

36196

64 Sidney Street

Cambridge MA 02139-4170 King of Prussia PA 19406-0901 Irvine CA 92623-9534 Iselin NJ 08830

1020 First Avenue 2525 Dupont Drive 99 Wood Avenue

PO Box 61501 P. O. Box 19534 Suite 311

34400

Fruebjergvej 3, 2100

Copenhagen

39331

7000 Portage Road

Kalamazoo MI 49001-0199 Toronto, Ontario M4P 3B

34845

160 Eglinton Ave. East 30 Forest Notch

Suite 600 Cohasset MA 02025

1095 10th Avenue S.E.

Minneapolis MN 55414 Salt Lake City UT 84132

University Of Utah Medical Center

50 North Medical Drive, Room 4R240

2-31 Koraibashi, Higashi-ku

Osaka 541

1000 Madison Ave.

Norristown PA 19403

1000 Madison Ave.

Norristown PA 19403

1000 Madison Ave.

Norristown PA 19403

1620 Waukegan Road

McGaw Park IL 60085

3300 Hyland Avenue 2800 Plymouth Rd., P.O. Box 1047

Costa Mesa CA 92626 Ann Arbor MI 48106

35640

2400 West Lloyd Expressway

Evansville IN 47721

Route 611, P.O. Box 187

Swiftwater PA 18370

10 DeAngelo Drive

Bedford MA 01730

Langes Feld 13

Hameln

38210

153 Second Avenue

Waltham MA 02451

640 Sasco Hill Road

Fairfield CT 06824

11008 Lamplighter Lane

Potomac MD 20854

130 Fifth Ave., N.

Seattle WA 98109-4933

130 Fifth Ave., N. 5 Moore Drive

Seattle WA 98109-4933 Research Triangle Park NC 27709

31524

1301 Piccard Drive

Rockville MD 20850

800 South Frederick Avenue 610 Herndon Parkway

Gaithersburg MD 20877 Suite 750 Herndon VA 20170 La Jolla CA 920930624

c/o Univ. of Calif., San Diego

9500 Gilman Dr.

7301 East 22nd Street 7301 East 22nd Street

Suite 10E Suite 10E

Tucson AZ 85710 Tucson AZ 85710

33 Flying Point Road 1900 Patterson Street 3505 Riverview Circle

Southampton NY 11968 Suite 104 Moorhead MN 56560 Nashville TN 37203

29949 S.R. 54 West

Wesley Chapel FL 33543

103 Carnegie Center, Suite 102 4470 Redwood Highway Chestnut Run, Maple Run

Princeton NJ 08540 San Rafael CA 94903 Centre Rd. Wilmington DE 19805

2215 Mock Road

Huntsville AL 35801 San Diego CA 921213088 Overland Park KS 66210

9373 Towne Center Dr.

Suite 100

9200 Indian Creek Parkway

Building 9, Suite 200

1000 Madison Ave

Norristown PA 19403

920 US Highway 202

P. O. Box 300

Raritan NJ 08869

460 Point San Bruno Boulevard

South San Francisco CA 94080

34333

One Health Plaza

East Hanover NJ 07936-1080

920 US Highway 202, P. O. Box 300

Raritan NJ 08869

39219

215Bouchard Blvd

Dorval

Quebec H9S 1A9

1550 Plymouth St.

PO Box 7210

Mountain View CA 94039-7210

36339

59, Bd Gal Martial Valin - 75015

Paris

100 Technology Drive 901 Sawyer Rd.

Suite 440 B Marietta GA 30062

Pittsburgh PA 15219

33960

13950 Ballantyne Corporate Place

Charlotte NC 28277

207 South Elliott Road PMB#231 200 First Street Southwest

Chapel Hill NC 27514 Rochester MN 55905

200 First Street Southwest

Rochester MN 55905

352 Knotter Drive

Cheshire CT 06410

352 Knotter Drive 59 Route 10/Bldg 122/N142 11080 CirclePoint Road

Cheshire CT 06410 One Health Plaza Suite 200 East Hanover NJ 07936-1080 Westminster CO 80020

39157

460 Seaport Court

Redwood City CA 94063

P.O. Box 9627 P.O. Box 9627

Kansas City MO 64134 Kansas City MO 64134

33205

10 Mountainview Road Parke-Davis Pharmaceutical Research Division 2825 Santa Monica Blvd.

Upper Saddle River NJ 07458

2800 Plymouth Road 2nd Floor

Ann Arbor MI 48105 Santa Monica CA 90404-2429

4620 Creekstone Drive 4901 Searle Parkway 4901 Searle Parkway

Research Triangle Park Skokie IL 60077 Skokie IL 60077

Durham NC 27703

200 West Arbor Drive

San Diego CA 92103-8450

Lilly Corporate Center 500 Iolab Drive P.O. Box 151

Indianapolis IN 46285 Claremont CA 91711 Somerville NJ 08876 Kalamazoo MI 4900136418 0199

0634-298-113

7000 Portage Rd.

1840 Dehavilland Drive

Thousand Oaks CA 91320

33238

1840 Dehavilland Drive

Thousand Oaks CA 91320 Raritan NJ 088690602

32660

920 U.S. Highway

Route 202, P.O. Box 300

Route 202 South

P.O. Box 300

Raritan NJ 08869 Raritan NJ 088690602

920 US Highway 202 Route 202, P.O. Box 300

P.O. Box 300 Raritan NJ 08869

3780 Hawthorn Court

Waukegan IL 60087

Five Moore Dr.

PO Box 13398

Research Triangle Park NC 27709-3398 36630

5 Moore Drive 5 Moore Drive 301 Henrietta Street

Research Triangle Park NC 27709 Research Triangle Park NC 27709 Kalamazoo MI 49001

34962

300 American Road

Morris Plains NJ 07950

7220 Frederick Banting, Suite 100

Saint-Laurent

Quebec H4S 2A1 Houston TX 770302399

Feigin Center

Suite 1120

1 DNA Way

South San Francisco CA 94080-4990

1980 South Easton Road

Suite 250

Doylestown PA 18901

P.O. Box 516, 107/2 MS10

St. Louis MO 63166

607 Herndon Parkway

Herndon VA 21070

51 University St.

Seattle WA 98101-2936

36307

Parc Technologique du Canal

31521 Ramonville Saint Agne Cedex

Parc Technologique du Canal 257 Cornelison Avenue

31521 Ramonville Saint Agne Cedex Jersey City NJ 07302

32499

70 Wood Avenue, South 100 Front Street Kings Park House, Laurelhill Business Park

Iselin NJ 08830 West Conshohocken PA 19428

Polmaise Road, Stirling FK7 9JQ Bloomington MN 55438-2318 Bloomington MN 55438-2318 Bloomington MN 55437-3107

6300 West Old Shakoppe Rd.

Suite 110

6300 West Old Shakoppe Rd. 5775 West Old Shakoppe Rd.

Suite 110 Suite 100

31888

Two Annabel Lane, Suite 220

San Ramon CA 94583 San Ramon CA 94583

Two Annabel Lane, Suite 220

Suite 10

2001 Aliceanna Street 7000 Portage Road 58 South Service Road

Baltimore MD 21231-3043 Mail Stop: 0636-298-113 Suite 110 Kalamazoo MI 4900136454 0199 Melville NY 11747

100 College Road West 100 College Road West

Princeton NJ 08540 Princeton NJ 08540 King of Prussia PA 19406-0901

1020 First Ave.

PO Box 61501

4225 Roosevelt Way

Seattle WA 98105

15 Skyline Dr.

Hawthorne NY 10532

15 Skyline Dr.

Hawthorne NY 10532

301B College Road East

Princeton NJ 08540

34179

Fetcham Park House

Leatherhead, Surrey KT22 9HD

61 Lincoln's Inn Fields

London WC2A 3PX Los Angeles CA 90027 Frankfurt

Childrens Hospital Los Angeles Weissfrauenstr.9

4650 Sunset Blve, MS 55 D-60287

100 Pelican Way 5555 Valley Boulevard

San Rafael CA 94901 Los Angeles CA 90032

310 East 67th Street

New York NY 10021

9342 Jeronimo Road

Irvine CA 92718

1840 Dehavilland Drive

Thousand Oaks CA 91320

34687

1840 Dehavilland Drive

Thousand Oaks CA 91320

1840 Dehavilland Drive

Thousand Oaks CA 91320

34500

One Amgen Center Dr. One Amgen Center Dr.

Thousand Oaks CA 91320-1799 Thousand Oaks CA 91320-1799

35887

1840 Dehavilland Drive

Thousand Oaks CA 91320

35061

160 East 34th Street 15049 San Pablo Avenue, P.O. Box 4099 15049 San Pablo Avenue Post House, Suite 213

New York NY 10016 Richmond CA 94804 P.O. Box 4099 1720 Post Road East Richmond CA 948040099 Westport CT 068805643

33346

P.O. Box 200

Titusville NJ 08560

8500 Hidden River Parkway Division of American Cyanamid Company 340 Kingsland Street 340 Kingsland Street

Tampa FL 33637 401 N. Middletown Road Nutley NJ 07110-1199 Nutley NJ 07110-1199 Pearl River NY 10965

38450

194 Bureaux de la Colline - Batiment D

92213 Saint-Cloud Cedex New York NY 100296574 New York NY 100296574

The Mount Sinai School of Medicine

One Gustave L. Levy Place

Dept. of Psychiatry

Box 1230, One Gustave L. Levy Place

100 Longwater Circle

Norwell MA 02061

36670

3180 Porter Drive

Palo Alto CA 94304

36868

3180 Porter Drive

Palo Alto CA 94304

35768

2800 Plymouth Road 3260 Whipple Road

Ann Arbor MI 48106 Union City CA 94587-1217

35282

Av de Sevelin, 18-20

Lausanne, Switzerland South San Francisco CA 94080 South San Francisco CA 94080

1140 Veterans Blvd.

Suite A

1140 Veterans Blvd. Parke-Davis Pharmaceutical Research Division

Suite A

2800 Plymouth Road

Ann Arbor MI 48105

1845 Tonne Road 18-01 River Road

Elk Grove Village IL 60007 Fair Lawn NJ 07410

33255

University of Massachusetts Medical Center

55 Lake Avenue

Worcester MA 01655

21 Business Park Drive

Branford CT 06405

3110 Cherry Palm Drive

Tampa FL 33619

9342 Jeronimo Road 3401 Hillview Avenue 3030 Cornwallis Road

Irvine CA 92718-1903 Palo Alto CA 94304 P.O. Box 12700 Research Triangle Park NC 27709

35128 32682

1401 Eye Street, N.W. Suite 900

Washington DC 20005 Thousand Oaks CA 91320-1799

One Amgen Center Drive

Mail Stop 17-2-A

PO Box 8299

Philadelphia PA 19101-8299

36663

1 Fitzroy Mews

London W1T6DE

10660 Scripps Ranch Blvd.

Suite 200

San Diego CA 92131

505 Irving Avenue 9 West 57th Street One Research Way

Syracuse NY 13210 Suite 3825 Princeton NJ 08540 New York NY 100192701

1510 Delp Drive

Kulpsville PA 19443

35419

1090 Horsham Road

North Wales PA 19454

5214 Maryland Way, Suite 405

Brentwood TN 37027

4364 South Alston Avenue

Durham NC 27713

38148

Subsidiary of Medicis Pharmaceutical Corporation

Scottsdale AZ 85258 Kennedy Krieger Institute, 707 North Broadway Suite 1800

Johns Hopkins University Five Concourse Parkway

Baltimore MD 21205 Atlanta GA 30328

200 Great Valley Parkway

Malvern PA 19355-1307

400 Rella Boulevard, Suite 201

Suffern NY 10901

32791

The New York Hospital - Cornell Medical Center 525 East 68th Street, Box 70

New York NY 10021

500 Kendall Street 2000 Galloping Hill Road 2000 Galloping Hill Road

Cambridge MA 02142 Kenilworth NJ 07033 Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road 12280 Wilkins Avenue One Enterprise Way 59 Route 10

Kenilworth NJ 07033 Rockville MD 20852 Aliso Viejo CA 92656 East Hanover NJ 07936-1080 Corona CA 917181900 Wallingford CT 06492-7660

311 Bonnie Circle

PO Box 1900

5 Research Parkway

P.O. Box 5100

352 Knotter Drive

Cheshire CT 06410 Philadelphia PA 19101

One Franklin Plaza

P.O. Box 7929

33809

Textile House, 2 Koifman St.

Tel-Aviv 68012 Gaithersburg MD 20878 Chesterfield MO 63017

9801 Washingtonian Blvd 16020 Swingley Ridge Road

Suite 220 Suite 145

Immeuble Le Guillaumet

92046 Paris La Defense 92056 Paris La Defense

Immeuble Le Guillaumet

70 avenue du General de Gaulle,

Diagnostics Division University Of Massachusetts Medical Center

Abbott Park IL 60064

30517

55 Lake Avenue North

Worcester MA 01655

1 Prospect West

Wiltshire SN14 6FH

261 Aldwick Road 96 Skyway Avenue 12280 Wilkins Avenue

West Sussex PO21 3QU M9W 4Y4 Rockville MD 20852

12276 Wilkins Avenue 65 Hayden Avnue

Rockville MD 20852 Lexington MA 02421

938 Clopper Road 777 Old Saw Mill River Road 777 Old Saw Mill River Road

Gaithersburg MD 20878 Tarrytown NY 10591 Tarrytown NY 10591

33 Hayden Avenue University of Texas Medical Branch at Galveston

Lexington MA 02421 Route J-09, 700 The Strand Galveston TX 77550

39205

Meridian Center III

6 Industrial Way West

Eatontown NJ 07724

33596

4954 Van Nuys Boulevard 9373 Towne Centre Dr., Suite 100

Sherman Oaks CA 91403 San Diego CA 92121

2730 Wilshire Blvd. #110

Santa Monica CA 90403

500 Arcola Road

Collegeville PA 19426 San Diego CA 194262655

Nventa Biopharmaceuticals Corporation 6055 Lusk Boulevard

34801 Campus Drive

Fremont CA 94555 Framingham MA 01701-9322

c/o Genzyme Corporation

1 Mountain Rd.

1801 Maple Avenue

Suite 4300

Evanston IL 60201

519 Route 173 West

Bloomsbury NJ 08804

Tolbodgade 33

DK-1253 Copenhagen K

200 Great Valley Parkway 200 Great Valley Parkway

Malvern PA 19355-1307 Malvern PA 19355-1307

One Kendall Square

Cambridge MA 02139

500 Kendall Street 66 Ford Road

Cambridge MA 02142 Denville NJ 07834

70 Calle Encanto

Tucson AZ 85716

70 Calle Encanto

Tucson AZ 85716

7310 Turfway Road 244 Great Valley Parkway 244 Great Valley Parkway

Suite 490 Malvern PA 19355 Malvern PA 19355

Florence KY 41042

P. O. Box 625

5800 Park of Commerce Blvd., NW 5800 Park of Commerce Blvd., N.W.

Boca Raton FL 33487 Boca Raton FL 33487

5800 Park of Commerce Blvd., NW

Boca Raton FL 33487

519 Route 173 West

Bloomsbury NJ 08804

5 Research Parkway 140 West 57th Street 322 East Main Street Rehhagstrsase

Signature 91 Bldg/3SIG-3012 New York City NY 10019 Branford CT 06405

Wallingford CT 06492

200 Great Valley PArkway

Malvern PA 19355-1307

5885 Trinity Parkway

Suite 350

Centreville VA 20120

Koigle Alle 6

1000 Research Parkway

Meriden CT 06450

200 Great Valley Parkway

Malvern PA 19355-1307

1500 East Gude Drive

Rockville MD 20850

500 Kendall Street

Cambridge MA 02142

Building 75, 3rd. Ave. 340 Kingsland Street

Charlestown Navy Yard Nutley NJ 07110-1199

Charlestown MA 02129

3030 Callan Rd.

San Diego CA 92121

600 Alexander Park

Suite 304

Princeton NJ 08540

210 Welsh Pool Road 1301 Shoreway Road

Exton PA 19341 Suite 320 Belmont CA 94002

790 W. Frontage Road

Suite 125

Northfield IL 60093

37 rue Saint Romain

69008 Lyon

39066

3180 Porter Drive

Palo Alto CA 94304 Elk Mountain WY 82324

Mile 5.0 Pass Creek Road

PO Box 24

6200 Seaforth Street

Baltimore MD 21224

P.O. Box 4000

Princeton NJ 08543

35851

2751 Centerville Rd., Suite 210

Wilmington DE 19808

2751 Centerville Rd., Suite 210

Wilmington DE 19808

840 Memorial Drive

Second Floor

Cambridge MA 02139 Philadelphia PA 19101

d/b/a GlaxoSmithKline

P. O. Box 7929

5200 research Place

San Diego CA 92122 Westport CT 068805643

37306

1720 Post Road East

Suite 213

1720 Post Road East

Suite 213

Westport CT 068805643

38820

Invalidenstr. 130

10115 Berlin

Invalidenstr, 130

10115 Berlin

Renal Division

1620 Waukegan Road

McGaw Park IL 60085 37610 Kalamazoo MI 490010199 Kalamazoo MI 490010199

7000 Portage Road

Unit 0633-298-113

7000 Portage Road P.O. Box 16529

Unit 0633-298-113 Columbus OH 43216

33143
Kalamazoo MI 490010199

7000 Portage Road

Unit 0633-298-113

Hammerstrasse 47

Hammerstrasse 47

Hammerstrasse 25

CH-4410 Liestal

225 East Deerpath, Suite 250

Lake Forest IL 60045

700 Main Street

Cambridge MA 02139

38922

5 Research Parkway, P.O. Box 5100

Wallingford CT 06492

32507

P.O. Box 4000

Princeton NJ 08543-4000

P.O. Box 4000

Princeton NJ 08543

150 Field Drive

Suite 195

Lake Forest IL 60045

1210-885 West Georgia

Vancouver, British Columbia

San Diego

5000 Shoreline Court

South San Francisco CA 94080

38350

300 Fairfield Road

Wayne NJ 07470

300 Fairfield Road

Wayne NJ 07470

59 Route 10

East Hanover NJ 07936-1080

37021

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza 244 Great Valley Parkway

East Hanover NJ 07936-1080 Malvern PA 19355

37288

4380 N. Campbell Ave.

Tucson AZ 85718

2321 Camino La Zorrela

Tucson AZ 85718

2321 Camino La Zorrela

Tucson AZ 85718

2321 Camino La Zorrela One Kendall Square

Tucson AZ 85718 Cambridge MA 02139-1562

34477

15222 Avenue of Science

Suite C

San Diego CA 92128

8368 US 70 West

Clayton NC 27520

Plasma Fractionation Institute

Ramat Gan 52621

Wankdorfstrasse 10

CH-3000 Bern 22

Baxter Bioscience

Westlake Village CA 91362

750 Lexington Avenue

New York NY 10022

155 East 56th Street

New York NY 10022

750 Lexington Avenue, 19th Floor

New York NY 10022

Pharmaceutical Division, Biological Products

400 Morgan Lane

New Haven CT 06516 34330 King of Prussia PA 19406-0901

1020 First Avenue

P.O. Box 61501

2 Tesseneer Drive

Highland Heights KY 41076

Research Center

27 Village Lane

Wallingford CT 06492

76 Rogers Street

Cambridge MA 02142

244 Great Valley Parkway 11095 Torreyanna Road

Malvern PA 19355 San Diego CA 92196

9701 Richmond Avenue

Houston TX 77042 Malvern PA 193551307

200 Great Valley Parkway

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

38856

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

36031

2250 Holcombe Blvd 8995 Westside Parkway Suite 150

Houston TX 77030 Alpharetta GA 30004

3, allee des sequoias*

69760 LIMONEST - France

897 West Sixteenth Street

Newport Beach CA 92663

340 Kingsland Street

Nutley NJ 07110

34991

340 Kingsland Street 340 Kingsland Street 340 Kingsland Street

Nutley NJ 07110-1199 Nutley NJ 07110 Nutley NJ 07119

340 Kingsland Street 340 Kingsland Street 340 Kingsland Street

Nutley NJ 07110 Nutley NJ 07110-1199 Nutley NJ 07110-1199

32468

2000 Galloping Hill Road

Kenilworth NJ 07033

32468

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road 5 Moore Drive

Kenilworth NJ 07033 Research Triangle Park NC 27709

3030 Cornwallis Road

Research Triangle Pk NC 27709

14 Cambridge Center 14 Cambridge Center

Cambridge MA 02142 Cambridge MA 02142

14 Cambridge Center 15049 San Pablo Avenue, P.O. Box 4099

Cambridge MA 02142

Richmond CA 94804

100 Longwater Circle

Norwell MA 02061

14 Cambridge Center

Cambridge MA 02142

35202

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center 100 Longwater Circle

Cambridge MA 02142 Norwell MA 02061

4560 Horton Street

Emeryville CA 94608

34173

3280 Bayshore Blvd 1710 Gilbreth Road,

Brisbane CA 94005 Suite 301 Burlingame CA 94010-1317

33227 36566

1 DNA Way

South San Francisco CA 94080-4990

Center for Cancer Drud Discovery and Development

9500 Euclid Avenue

Clevland OH 44195

51 University Street 51 University Street

Seattle WA 98101 Seattle WA 98101

One Amgen Center Drive One Amgen Center Drive 777 Old Saw Mill River Road

Thousand Oaks CA 91320-1799 Thousand Oaks CA 91320-1799 Tarrytown NY 10591

777 Old Saw Mill River Road 340 Kingsland Street

Tarrytown NY 10591 Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street 340 Kingsland Street 51 University Street

Nutley NJ 07110 Nutley NJ 07110 Seattle WA 98101

59 Route 10 1120 Win Drive

East Hanover NJ 07936 Bethlehem PA 18017

39 Jerusalem Street

101 Carnegie Center

Princeton NJ 08540

101 Carnegie Center Div. of Draxis Specialty Pharmaceuticals, Inc.

Princeton NJ 08540

Kirkland, Quebec H9H 4J4

160 Second street

Cambridge MA 02142 Ann Arbor MI 481090028

UH B1 H410/0028 312 Lacebark Street

1500 E. Medical Center Drive Schererville IN 46375

32953

312 Lacebark Street

Schererville IN 46375

University of Michigan Medical Center/1500 E. Med.

B1G412 /0028 University Hospital

Ann Arbor MI 481090028

300 American Road

Morris Plains NJ 07950

300 American Road 300 American Road

Morris Plains NJ 07950 Morris Plains NJ 07950

300 American Rd.

Morris Plains NJ 07950

American Cyanamide Company

401 N. Middletown Road

Pearl River NY 10965

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Road 300 American Road

Morris Plains NJ 07950 Morris Plains NJ 07950

14282 Franklin Ave.

Tustin CA 92780-7017 Bloomington MN 55437-3107 Bloomington MN 55437-3107

5775 West Old Shakoppe Rd.

Suite 100

5775 West Old Shakoppe Rd.

Suite 100 D-14167 Berlin, Federal Republic of Germany

Goerzallee 253

37896

5555 Valley Boulevard Boston University

Los Angeles CA 90032 Cancer Research Center Boston MA 02118

6 Cedar Brook Drive

Cranbury NJ 08512

Room 307, Koryo Academytel, 437-3 28101 Ballard Road

Ahyun-Dong, Mapo-Gu, Seoul 121-010 Lake Forest IL 60045

640 Memorial Drive, 3rd Floor West

Cambridge MA 02139

640 Memorial Drive, 3rd Floor West

Cambridge MA 02139 Corona CA 917181900 Farmingdale NY 11735

311 Bonnie Circle SUNY Farmingdale

P.O. Box 1900 Conklin Hall

800 S. Frederick Avenue

Gaithersburg MD 20877

800 S. Frederick Ave. P.O. Box 16532

Gaithersburg MD 20877 Columbus OH 43216-6532

200 International Circle

Hunt Valley MD 21030 Research Triangle Park NC 27709

5 Moore Drive

P.O. Box 13398

36031

27 Maple Street 371 Bel Marin Keys Boulevard, Suite 210

Milford MA 01757

39324

Novato CA 94949-5608

37741

1101 Kermit Drive, Suite 608

Nashville TN 37217

6111 Royalmount, Suite 100 6111 Royalmount, Suite 100

Montreal, Quebec H4P 2T4 Montreal, Quebec H4P 2T4

6111 Royalmount, #100 University Of Pittsburgh School of Medicine The City College, City University Of NY Medical Sc Channing Laboratory Rush-Presbyterian-St. Luke's Medical Ctr., Dept. o

Montreal, Quebec H4P 2T4

Pittsburgh PA 15261

Convent Avenue at 138 Street Dept. of Medicine 1653 West Congress Parkway

New York NY 10031 Boston MA 02115 Chicago IL 606123833

86 Morris Avenue

Summit NJ 07901

38713

86 Morris Avenue

Summit NJ 07901

86 Morris Avenue

Summit NJ 07901

38897

200 West Jackson Blvd.

Chicago IL 60606

Frankfurt am Main

P.O. Box 1140

Marburg

35860

41 Moores Road 51 University Street 51 University Street 5 Moore Drive 8229 Boone Blvd.

Frazer PA 19355 Seattle WA 98101 Seattle WA 98101 PO Box 13398 Suite 802 Research Triangle Park NC 27709 Vienna VA 22182 Stony Brook NY 11794-8181

33584 32386

S.U.N.Y. at Stony Brook

H.S.C. T18-020

2355 Waukegan Road

Deerfield IL 60015

34075

500 Iolab Drive

Claremont CA 94608

800 South Frederick Avenue, Suite 300 Gaithersburg MD 20877 800 South Frederick Avenue 800 South Frederick Avenue 800 South Frederick Avenue Gaithersburg MD 20877 Gaithersburg MD 20877 Gaithersburg MD 20877

36509

800 S. Frederick Avenue, Suite 300

Gaithersburg MD 20877

800 South Frederick Avenue

Gaithersburg MD 20877

800 South Frederick Avenue

Gaithersburg MD 20877

33954

800 South Frederick Avenue

Gaithersburg MD 20877

31512

901 Sawyer Road

Marietta GA 30062

8180 Greensboro Drive, Suite 1000

McLean VA 22102 Torrance CA 905037701

34159

3870 Del Amo Blvd

Unit 507

P. O. Box 2072.

Toowong Business Center

600 College Road East 745-D Camden Ave.

Princeton NJ 08540 Campbell CA 95008-4146

36238

21823 30th Drive Southeast

Bothell WA 98021

21823 30th Drive Southeast

Bothell WA 98021

34801 Campus Drive

Fremont CA 94555

One Franklin Plaza

P.O. Box 7929

Philadelphia PA 19101 Framingham MA 01701-9322

33603

Metrowest Place

15 Pleasant Street Connector

3 Parkway North Center

Deerfield IL 60015

3 Parkway North Center

Deerfield IL 60015

35653

3 Parkway North Center

Deerfield IL 60015

35653

420 Lexington Avenue

New York NY 10170

420 Lexington Avenue

New York NY 10170

3929 Point Eden Way

Hayward CA 94545

3929 Point Eden Way

Hayward CA 94545

11 Deer Park Drive

Monmouth Junction NJ 08852-1923

Baylor College of Medicine, Dept. of Molecular Phy

One Baylor Plaza

Houston TX 77030

Pol. Ind. Els Vinyets els Fogars n 2,

Quinti de Mediona

Barcelona

900 North Shore Drive

Lake Bluff IL 60044

900 North Shore Drive

Lake Bluff IL 60044

M.D. Anderson Cancer Center

Unit 038

Houston TX 77030

20651 Prince Creek Dr.

Katy TX 77450

One Research Way

Princeton NJ 08540

3 Forbes Road

Lexington MA 02421

2011 - 94th Street

Edmonston, AB

2011 - 94th Street 201 Elliot Avenue West201

T6N 1H1 Suite 400 Seattle WA 98119

181 Cherry Valley Road 181 Cherry Valley Road

Princeton NJ 08540 Princeton NJ 08540

6201 South Freeway

Fort Worth TX 76134

34235

Route 202, P.O. Box 300

Raritan NJ 08869

99 Hayden Ave., Suite 200

Lexington MA 02421-7966

12832 Chadron Avenue

Hawthorne CA 90250

1801 Maple Avenue Subsidiary of China Medical System Holdings Limite

Suite 4300

Evanston IL 60201

Room 1404, 14th Floor

North Point

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

4901 Searle Parkway

Skokie IL 60077 Morgantown WV 26504-4310

781 Chestnut Ridge Road

P.O. Box 4310

35951

Route 120 & Wilson Road

Round Lake IL 60073-0490

26 Landsdowne Street

Cambridge MA 02139-4234

10 Rodborough Rd.

NSW 2086

P. O. Box 28 397 Eagleview Blvd.

Richlands 4077 Exton PA 19341

3 Francis St.

Belmont MA 02478

860 Atlantic Avenue

Alameda CA 94501 San Diego CA 921211113

10865 Altman Row

Suite 200

176 Memorial Drive

Jesup GA 31545 Winston-Salem NC 27101-4165

200 East First St.

Suite 300

41 Moores Road

P. O. Box 4011

Frazer PA 19355

2000 Sierra Point Parkway

Suite 400

Brisbane CA 94005

38594

8720 Stony Point Parkway

Suite 200

Richmond VA 23235

38698

259 Radnor Chester Road

Radnor PA 19087

One MedImmune Way

Gaithersburg MD 20878

1787 Sentry Parkway West

Building 18, Suite 440

Blue Bell PA 19422

4143 Dornach

POSTFASH 137

4143 Dornach 340 Kingsland Street 340 Kingsland Street

POSTFASH 137 Nutley NJ 07110 Nutley NJ 07110

32630 32630

2400 West Lloyd Expressway Hoag Cancer Center Cell Biology Laboratory

Evansville IN 47721 Newport Beach CA 92658

34222

Building 41

2110 Rutherford Road 5 Research Parkway

Carlsbad CA 92008 P. O. Box 5100 Wallingford CT 06492

533 Old Corvallis Road 8 Hanechoshet St. Oregon Health Sciences University

Hamilton MT 59840 Tel-Aviv 3181 S.W. Sam Jackson Park Road Portland OR 97201 Ridgefield CT 0687738575 0368 Research Triangle Park NC 27709

900 Ridgebury Road 5 Moore Drive 5 Moore Drive

P. O. Box 368 PO Box 13398 Research Triangle Park NC 27709

33926

146 Medinah Drive

Blue Bell PA 19422-3212

146 Medinah Drive

Blue Bell PA 19422-3212

P.O. Box 7929 1800 Concord Pike 890 East St. 65 Challenger Road

Philadelphia PA 19101 PO Box 15437 Tewksbury MA 01876-1496 Ridgefield Park NJ 07660 Wilmington DE 19850-5437

32507

90 Gold Street, 6N

New York NY 10038

P.O. Box 8299 Division of American Cyanamid Company

Philadelphia PA 19101-8299

401 N. Middletown Road

Pearl River NY 10965 32240 Durham NC 277132280

200 Westpark Corporate Center

4364 South Alston Avenue

437 Creamery Way

Exton PA 19431

9360 Towne Centre Drive 9360 Towne Center Drive

San Diego CA 92121 San Diego CA 92121

P.O. Box 331329 4901 Searle Parkway

Fort Worth TX 76163 Skokie IL 60077

P.O. Box 331329

Fort Worth TX 76163

32469

2988 Cove Trace 55 Knollwood Road

Charlottesville VA 22911 Farmington CT 06032

2530 Meridian Parkway

Suite 3023

Durham NC 27713

8010 Arco Corporate Drive

Raleigh NC 27617

Meridian Center III

6 Industrial Way West

Eatontown NJ 07724

35314

9 Parker 19, rue Frederick Lmaitre 149 Commonwealth Drive

Irvine CA 92618-1605 75020 Paris Menlo Park CA 94025

Gewerbestrasse 16

CH - 4123 Allschwi

37833

Weismullerstrasse 50 Division of American Cyanamid Company

401 N. Middletown Road

Pearl River NY 10965

Autoimmunity Research, Inc.

Thousand Oaks CA 91360

15 East 26th Street 4545 Horizon Hill Blvd.

New York NY 10010 San Antonio TX 78229-2263

990 Station Road

Bellport NY 11713

990 Station Road 3100 Airway Avenue, Suite 106

Bellport NY 11713 Costa Mesa CA 92626

One Technology Place

Rockland MA 02370

35382

One Technoloogy Place

Rockland MA 02370

36812

One Technology Place Division of American Cyanamid Company

Rockland MA 02370 401 N. Middletown Road

36812
Pearl River NY 10965 32134

300 American Rd.

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

145 Brandywine Parkway 2000 Galloping Hill Road

West Chester PA 19380 Kenilworth NJ 07033

36153

2000 Galloping Hill Road

Kenilworth NJ 07033

Ackerstein Towers, Bldg B, 10th Floor

ISRAEL

3030 Callan Road

San Diego CA 92121

11011 Torreyana Road

San Diego CA 92121

244 Great Valley Parkway

Malvern PA 19355

2825 Santa Monica Blvd., Suite 200

Santa Monica CA 90404

2375 Garcia Avenue 2375 Garcia Avenue 34801 Campus Dr.

Mountain View CA 94043 Mountain View CA 94043 Fremont CA 94555 Wellesley Hills MA 02481

15 Walnut Street

Suite 300

235 East 42nd Street

New York NY 10017 Research Triangle Park NC 27709

5 Moore Drive 7855 Gross Point Road, Unit L

PO Box 13398 Skokie IL 60077

31351

2 Esterbrook Lane 999 East Arques Avenue

Cherry Hill NJ 08003 Sunnyvale CA 94085-4521

33438

4330 La Jolla Village Drive 12280 Wilkins Avenue 12280 Wilkins Avenue

Suite #250 Rockville MD 20852 Rockville MD 20852

San Diego CA 92122

One Health Plaza 725 Chesterbrook Blvd.

East Hanover NJ 07936-1080 Wayne PA 19087-5677

Mack-Cali Centre II

Second Floor

Paramus NJ 07652

38239

14272 Franklin Ave.

Suite 100

Tustin CA 92780

West Africa House

Hanger Lane Ealing

London W5 3QR

345 Pioneer Drive, 1803W 5 Artillerivej

Glendale CA 91203 DK-2300 Copenhagen S

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110

128 Spring Street Abbott Laboratories

Lexington MA 02173 625 Cleveland Ave. Columbus OH 432151724

5600 Parkwood Way

Suite 425

3, avenue George V

One Amgen Center Drive

Thousand Oaks CA 91320-1799

130 Waverly St.

Cambridge MA 02139-4242

2525 - 28th Street

Boulder CO 80301

3, avenue George V Abbott Park IL 600646157

Pharmaceuticals Products Division

D-491, AP30-1E

555 Madison Avenue Global Pharmaceuticals Research & Development

New York NY 10022

Abbott Park IL 60064

93 Worcester Street

Suite 101

Wellesley MA 02481

93 Worcester Street

Suite 101

Wellesley MA 02481

93 Pederstrupvej

DK-2750 Ballerup Juncos UN 007773873 Dallas TX 753909151

Road 198, No. 100 km. 14.7 University of Texas Southwestern Medical Center at 105 Digital Drive

Juncos Industrial Park

5323 Harry Hines Blvd Novato CA 94949-5608

38503

11 Deer Park Drive

Monmouth Junction NJ 08852 Los Angeles CA 90048

8455 Beverly Blvd. 3560 Pennsylvania Avenue, Suite 7

Suite 308 Dubuque IA 52002

Pharmaceutical Products Division

200 Abbott Park Road

Abbott Park IL 60064

3401 Hillview Avenue

Palo Alto CA 94303

33660

E.I. Du Pont De Nemours & Co.

Wilmington DE 19880

31016

4134 Business Park Drive

Amarillo TX 79110

4134 Business Park Drive

Amarillo TX 79110

4134 Business Park Drive

Amarillo TX 79110 Copiaque NY 117260030

33 Ralph Avenue 200 Great Valley Parkway

P.O. Box 30 Malvern PA 19355

One Franklin Plaza

Phildelphia PA 19101

38653

6560 Fannin, Scurlock Tower, Suite 720 Houston TX 77303 400 Rella Boulevard, Suite 201 Suffern NY 10901

MetroHealth Medical Center

3395 Scranton Road

Cleveland OH 44109

University of Arizona

Tucson AZ 85723

One Health Plaza

East Hanover NJ 07936-1080

One Health Plaza

East Hanover NJ 07936-1080

5045 Orbitor Drive

Mississauga, Ontario L4W 4Y4 New Brunswick NJ 100 Jersey Avenue, Building B, Suite 310 08901

New Brunswick Technology Center

6200 Courtney Campbell Causeway

Suite 880

Tampa FL 33607

6200 Courtney Campbell Causeway

Suite 880

Tampa FL 33607

37582

6200 Courtney Campbell Causeway

Suite 880

Tampa FL 33607

37582

Kungsgatan 37, 7th Floor

SE-111 56

Drottninggatan 98

SE-111 60 Stockholm

37274

22705 Savi Ranch Parkway

Yorba Linda CA 92887-4645

6 Route 173

Clinton NJ 08809

54 Old Highway 22

Clinton NJ 08809

36517

54 Old Highway 22 Thomas Jefferson University and Wills Neurosensory La Jolla Laboratories

Clinton NJ 08809 834 Walnut Street, Suite 650 10646 Science Center Drive Philadelphia PA 19107-5102 San Diego CA 92121

675 Almanor Avenue

Sunnyvale CA 94085-1

640 S. Fourth Street

Louisville KY 40202

West Africa House 800 Research Parkway

London W5 3QR Suite 200 Oklahoma City OK 73104

5 Great Valley Parkway

Malvern PA 19355

5 Great Valley Parkway

Malvern PA 19355

5 Great Valley Parkway

Malvern PA 19355

Two Connell Drive 59 Route 10

Berkeley Heights NJ 07922 East Hanover NJ 07936-1080

36124

59 Route 10

East Hanover NJ 07936-1080

36124

59 Route 10

East Hanover NJ 07936-1080

36124

2525 Dupont Drive

P.O. Box 19534

Irvine CA 92713

35207

P. O. Box 2072

Toowong Business Center

6001 Savoy, Suite 110

Houston TX 77036

3715 Haven Avenue

Menlo Park CA 94025

4364 South Alston Avenue

Durham NC 27713

PO Box 420

1327 Lysaker

600 College Road East

Princeton NJ 08540

87 Cambridge Park Drive

Cambridge MA 02140

35759

863 Mitten Road, Suite 101

Burlingame CA 94010

6040 N. Cutter Circle, Suite 317

Portland OR 97217-3935

40 Landsdowne Street

Cambridge MA 02139

37754

Rue des Terreaux 17

CH-1000

13709 Progress Blvd. #17

Alachua FL 32615

70 Wood Avenue, South

Iselin NJ 08830

70 Wood Avenue, South

Iselin NJ 08830

One Tower Center Boulevard, 12th floor East Brunswick NJ 08816 One Tower Center Boulevard, 12 th floor East Brunswick NJ 08816 70 Wood Avenue South Iselin NJ 08830

3180 Porter Drive

Palo Alto CA 94304

38674

3180 Porter Drive

Palo Alto CA 94304

37454

P.O. Box 80027

Wilmington DE 19880

3650 Westbrook Mall

Vancouver, B.C.

4222 Emperor Blvd.

Suite 470

Durham NC 27703

4222 Emperor Blvd., Suite 470

Durham NC 27703

9410 Key West Avenue

Rockville MD 20850

5 Research Parkway

P.O. Box 5100

Wallingford CT 06492-7660

35646

4400 Biscayne Boulevard

Miami FL 33137

22026 20th Avenue SE

Bothell WA 98021

150 Fairway Drive

Vernon Hills IL 60061

150 Fairway Drive

Vernon Hills IL 60061

150 Fairway Drive

Suite 150

Vernon Hills IL 60061

22 Inverness Parkway

Birmingham AL 35242

One Health Plaza

East Hanover NJ 07936-1080

14851 N. Scottsdale Rd.

Scottsdale AZ 85254

417 Harvester Court

Wheeling IL 60090

300 Interpace Parkway 35 West Watkins Mill Rd.

Parsippany NJ 07054 Gaithersburg MD 20878

2420 Castillo Street, Suite 100

Santa Barbara CA 93105

One Health Plaza 20 Kingsbridge Road

East Hanover NJ 07936-1080 Piscataway NJ 08854

32953

20 Kingsbridge Road 49 Convent Dr. MSC4405

Piscataway NJ 08854 Bldg. 49, Room B1EE16 Bethesda MD 208924405

34366

340 Kingsland St.

Nutley NJ 07110-1199

340 Kingsland St. 4560 Horton Street

Nutley NJ 07110-1199 Emeryville CA 94608

Suite 430,

98 San Jacinto Boulevard

Austin TX 78701

37705

115 John Robert Thomas Dr.

Exton PA 19341

115 John Robert Thomas Dr. One Amgen Center Dr.

Exton PA 19341 Thousand Oaks CA 91320-1789

2190 Parkway Lake Drive

Birmingham AL 35244

Lilly Corporate Center 3 Parkway North Center

Indianapolis IN 46285 Deerfield IL 60015

38021 32674

3 Parkway North Center

Deerfield IL 60015 King of Prussia PA 19406-0901

30971

1020 First Avenue 755 Jefferson Rd., P.O. Box 1710 E.I. Du Pont De Nemours & Co. Goerzallee 253

PO Box 61501 Rochester NY 14603 Wilmington DE 19898 Fedderal of Republic of Germany

31916

950 Page Mill Rd.

PO Box 10950

Palo Alto CA 943030802

35334

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

33522

Avenida Carlos III el Noble Avenida Carlos III el Noble, 36, 1 Dcha. 31003

Pamplona (Navarra)

38 Melville Street

Scotland

3040 Science Park Road

San Diego CA 92191

2450 Bayshore Parkway Cincinnati Children's Hospital Medical Center

Mountain View CA 94043 Cincinnati OH 452293039

3333 Burnet Ave.

1300 Gould Dr.

Gainesville GA 30504

371 Bel Marin Keys Blvd.

Suite 210

Novato CA 94949

1300 Gould Dr.

Gainesville GA 30504

Unit 3, Hill Farm Industrial Estate

Leavesden, Watford Port Jefferson NY 11776 Bloomington MN 55437-3107

Port Jefferson Business Center

200 Wilson Street, Building D-6

5775 West Old Shakopee Rd.

Suite 100

34415

5775 West Old Shakopee Rd.

Suite 100

Bloomington MN 55437-3107

35837

1950 Lake Park Drive 3030 Cornwallis Road

Smyrna GA 30080 P.O. Box 12700 Research Triangle Park NC 27709

11000 Cedar Avenue

Cleveland OH 44106

10 Fleet Place

London EC4M 7SB

10 Fleet Place

London EC4M 7SB Cambridge MA 02139-4170 Cambridge MA 02139-4170

University Park at M.I.T.

The Richards Building 64

University Park at M.I.T.

The Richards Building 64

6611 Tributary Street

Baltimore MD 21224

37677

6611 Tributary Street 154 Technology Parkway

Baltimore MD 21224 Norcross GA 30092

35331

4606 Willow

Bellaire TX 77401

154 Technology Parkway

Norcross GA 30092

154 Technology Parkway

Norcross GA 30092 Philadelphia PA 19103 Philadelphia PA 19103 Philadelphia PA 19103 Philadelphia PA 19103

One Penn Center

1617 JFK Boulevard

One Penn Center

1617 JFK Boulevard

One Penn Center

1617 JFK Boulevard

One Penn Center

1617 JFK Boulevard

One Tower Center Boulevard, 14th floor East Brunswick NJ 08816

115 John Robert Thomas Dr. 115 John Robert Thomas Dr. 115 John Robert Thomas Dr.

Exton PA 19341 Exton PA 19341 Exton PA 19341

3202 Cleveland Avenue N.W.

Washington DC 20008

3203 Cleveland Ave., NW

Washington DC 20008-3450

3203 Cleveland Ave., NW

Washington DC 20008-3450

3203 Cleveland Ave., NW

Washington DC 20008-3450

P.O. Box 14

Bryn Mawr PA 19010

211 Central Park West

New York NY 10024

One Kendall Square

Cambridge MA 02139-1562

One Kendall Square

Cambridge MA 02139-1562

One Kendall Square

Cambridge MA 02129-1562

One Kendall Square

Cambridge MA 02139-1562

Post Office Plaza 22 Inverness Parkway

50 Division Street, Suite 503 Suite 310

Somerville NJ 08876 Birmingham AL 35242 37834

22 Inverness Parkway

Birmingham AL 35242

Lederle Laboratories Lederle Laboratories

401 North Middletown Road 401 North Middletown Road

Pearl River NY 10965 35060 Pearl River NY 10965

900 Ridgebury Road

PO Box 368

Ridgefield CT 06877

900 Ridgebury Road

PO Box 368

Ridgefield CT 06877

2000 Galloping Hill Road 5323 Harry Hines Blvd

Kenilwortoh NJ 07033 Dallas TX 75235

31289

5323 Harry Hines Blvd

Dallas TX 75235

31289

5323 Harry Hines Boulevard

Dallas TX 75235

31289

1733 Gilsinn Lane

Fenton MO 63026

2958101

1564 33rd Street, NW

Washington DC 20007

P. O. Box 93921

Carmel CA 93921

P. O. Box 93921

Carmel CA 93921

P. O. Box 93921 2 Innovation Drive

Carmel CA 93921 Alachua FL 32615

2 Innovation Drive

Alachua FL 32615

2 Innovation Drive 2 Innovation Drive

Alachua FL 32615 Alachua FL 32615

11080 CirclePoint Road 1 Kendall Square, Bldg. 700

Westminster CO 80020 Cambridge MA 02139

P.O. Box 16529 90 Park Avenue

Columbus OH 43216-6529 New York NY 10016

800 South Frederick Avenue 311 Bonnie Circle

Gaithersburg MD 20877 Corona CA 91720

Pharmaceuticals Division

8500 Hidden River Parkway

Tampa FL 33637

Research & Development Division 5555 Valley Boulevard

2-5-1 Atago, Minato-ku, Tokyo Los Angeles CA 90032

2159 Avenida de la Playa

Suite B

La Jolla CA 92037

One Baxter Way 750 Lexington Avenue, 19th Floor

West Lake Village CA 91362 New York NY 10022

39171

750 Lexington Avenue, 19th Floor 1950 Lake Park Drive

New York NY 10022 Smyrna GA 30080

200 Abbott Park Road

Abbott Park IL

2450 Bayshore Parkway 2751 Napa Valley Corporate Drive 200 Highland Avenue

Mountain View CA 94043 Napa CA 94558 Suite 30 Needham MA 02494

2958101

128 Spring Street

Lexington MA 02421

84 park Avenue

P.O. Box 968

Flemington NJ 08822

1100 Orthodox Street

Philadelphia PA 19124

38576

11455 El Camino Real

San Diego CA 92130

11801 Research Drive

Suite D

Alachua FL 32615

University of Pittsburgh

Pittsburgh PA 15213

Lilly Corporate Center

Drop Code 1853

Indianapolis IN 46285

225 Belleville Ave.

Bloomfield NJ 07003

1275 Kinnear Road

Columbus OH 43212

26 Landsdowne Street

Cambridge MA 02139-4234

9 Great Valley Parkway

Malvern PA 19355

37449

12085 Research Drive

Suite 110

Alachua FL 32615 East Hanover NJ 07986 East Hanover NJ 07936

Oncology Business Unit

One Health Plaza

Oncology Business Unit

One Health Plaza

2910 Seventh Street

Berkeley CA 94710

25 Riverside Drive

P.O. Box 102

Pine Brook NJ 07058

Kongevejen 153

2830 Virum

3575 av. du Parc

Montreal, Quebec H2X 3P9

Rue des Professeurs Jenner et Brachet, 12 B-6041-Gosselies 10 Four seasons Place Toronto ON M9B 6H7

6850 Goreway Dr.

Mississauga

One Kendall Square

Cambridge MA 02139

38835

1010 Atlantic Avenue

Alameda CA 94501

2020 Challenger Drive

Alameda CA 94501

Roslin, Edinburgh

EH259PP Scotland

1010 Atlantic Avenue

Alameda CA 94501

101 Binney Street

Cambridge MA 02142

Roskildevej 12 C

P. O. Box 8299 c/o Genzyme Corporation

Philadelphia PA 19101-8299 Framingham MA 15 Pleasant St. Connector, P.O. Box 9322 01701

Archimedesweg 4 Archimedesweg 4 Cipalstreet 3 Cipalstreet 3 B-2440 Geel B-2440 Geel

460 Point San Bruno Boulevard Kornhamnstorg 53

South San Francisco CA 94080 Box 2077

9640 Medical Center Drive

Rockville MD 20850

9640 Medical Center Drive

Rockville MD 20850

322 East Main Street 14 Cambridge Center

Branford CT 06405 Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02124

2400 Boston Street 800 Research Parkway

Baltimore MD 21224 Suite 200 Oklahoma City OK 73104

7000 Portage Road 7000 Portage Road Gate 11, Victoria Dr.

Kalamazoo MI 49001-0199 Kalamazoo MI 49001-0199 Adelaide SA 5000

41 Morres Road

P. O. Box 4011

Frazer PA 19355

P.O. Box 2400

Glen Allen VA 23058-2400

87 CambridgePark Drive

Cambridge MA 02140

1201 Eastlake Avenue East

Seattle WA 98102

One Amgen Center Dr.

Thousand Oaks CA 91320-1799

One Technology Place 3333 Vaca Valley Parkway

Rockland MA 02370 Vacaville CA 95688

38268

Unit 14, Bridgecourt Office Park

Dublin

One Health Plaza

East Hanover NJ 07936-1080

1 DNA Way

South San Francisco CA 94080

300 Technology Square

Cambridge MA 02139

389-A Nichol Hill Road

Franklin TN 37067

Roskildevej 12C

3400 Hillerod

Roskildevej 12C

3400 Hillerod

3400 West Bayshore Road 1 DNA Way

Palo Alto CA 94303 South San Francisco CA 94080-4990

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center 14 Cambridge Center

Cambridge MA 02142 Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

300 Technology Square

Cambridge MA 02139

One Amgen Center Dr.

Thousand Oaks CA 91320-1799

1301 Harbor Bay Parkway 190 Bath Road

Alameda CA 94502 Berkshire S11 3XE

866 Malcolm Road 866 Malcolm Road 938 Clopper Road

Burlingame CA 94010 Burlingame CA 94010 Gaithersburg MD 20878

3200 Walnut Street

Boulder CO 80301

3200 Walnut Street

Boulder CO 80301

14 Cambridge Center

Cambridge MA 02142

460 Point San Bruno Boulevard

South San Francisco CA 94080 Tigard, OR 972234332

9020 SW Washington Square Road

Suite 380

2929 Seventh Street

Berkeley CA 94710

9 Great Valley Parkway

Malvern PA 19355

146 Flanders Drive

Hillsborough NJ 08876

725 Chesterbrook Blvd.

Wayne PA 19087-5677

Via Campo di Pile

67100 - L'Aquila

3260 Whipple Road Bldg 10/Rm 2N236 DASS/PPCS/NIDCR/NIH 35 West Watkins Mill Road

Union City CA 94587-1217

10 Convent Drive Gaithersburg MD 20878

Bethesda MD 20892

35 West Watkins Mill Road

Gaithersburg MD 20878

35082

41 Moores Road

Frazer PA 19355 Overland Park KS 66210 Framingham MA 01701-9322 Abbott Park IL 600646135 Abbott Park IL 600646133

9200 Indian Creek Parkway

Building 9, Suite 200

One Mountain Road

P.O. Box 9322

Abbott Laboratories, Dept. 389, Bldg. J45 200 Abbott Park Rd. Abbott Laboratories, Dept. 389, Bldg. J45 200 Abbott Park Rd.

1100 Olive Way, Suite 100 4851 Lake Brooke Drive

Seattle WA 98101 Glen Allen VA 23060

Unit 14

Walkinstown Avenue

Dublin 12

104 Chancellor Matheson Road

Winnipeg, Manitoba

34782

3300 Hyland Avenue

Costa Mesa CA 92626

2000 Galloping Hill Road

Kenilworth NJ 07033

37831

148 Sidney Street

Cambridge MA 02139

148 Sidney Street 148 Sidney Street

Cambridge MA 02139 Cambridge MA 02139

148 Sidney Street

Cambridge MA 02139

148 Sidney Street 148 Sidney Street P.O. Box 16529

Cambridge MA 02139 Cambridge MA 02139 Columbus OH 43216

33961

235 East 42nd Street

New York NY 10017

201 Elliott Avenue West P.O. Box 9627

Suite 150 Kansas City MO 64134

Seattle WA 98119

32653

P.O. Box 9627 P.O. Box 9627

Kansas City MO 64134 Mail Station: H3-M2516 Kansas City MO 64134-0627 Kansas City MO 64134-0627 Kansas City MO 64134-0627

34485

P.O. Box 9627

Mail Station: H3-M2516

P.O. Box 9627

Mail Station: H3-M2516

35968

1700 Perimeter Park Drive

Morrisville NC 27560

111 Rock Road

Horsham PA 19044-2310 Collegeville PA 19426-0800

500 Arcola Road

PO Box 5096

500 Arcola Road, P.O. Box 1200

Collegeville PA 19426

35045

8700 Mason-Montgomery Road

Mason OH 08807

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way, MS 242

South San Francisco CA 94080-4990

35760

5200 Research Place

San Diego CA 92122

126 East Lincoln Ave.

Rahway NJ 07065

780 Memorial Drive

Cambridge MA 02139

One Broadway 7000 Portage Road

Cambridge MA 02142 Kalamazoo MI 49001-0199

7327 Oak Ridge Highway

Knoxville TN 37931

Byk-Gulden StraBe 2

78467 Konstanz

220 Park avenue 4140 Dublin Blvd.

Florham Park NJ 07932 Suite 200 Dublin CA 94568

55 Challenger Road

Ridgefield NJ 07660

9640 Medical Center Dr.

Rockville MD 20850

12419 198th Drive, NE

Woodinville WA 98072

35894

90 Gold Street, 6N

New York NY 10038

1550 Sawgrass Corporate Parkway

Sunrise FL 33323

51 University Street

Seattle WA 98101

33302

51 University Street

Seattle WA 98101 Godmanchester, Cambridgeshire PE29 2HY

34957

Corpus Christi House

600 College Road East

Princeton NJ 08540

33967

1250 S. Collegeville Road

Collegeville PA 19426-0989

666 Sherbrooke Street West, Suite 1400 Montreal, Quebec

2000 Galloping Hill Rd.

Kenilworth NJ 07033 Vancouver, BC V6T 1Z3

190 Agronomy Road (UBC)

Suite 405

650 Cathill Rd.

Sellersville PA 18960

1885 33rd Street

Boulder CO 80301

777 South Harbor Island Boulevard 100 Longwater Circle

Tampa FL 33602 Norwell MA 02061

32664 35699

One Technology Place

Rockland MA 02370

One Technology Place

Rockland MA 02370

1668 Valtec Lane

Boulder CO 80306

21823 30th Drive Southeast

Bothell WA 98021

21823 30th Drive, Southeast

Bothell WA 98021

21823 30th Drive Southeast

Bothell WA 98021

1000 Central Street, Suite 615 1000 Central Street, Suite 615

Evanston IL 60201 Evanston IL 60201

1690 Russell Road

PO Box 1766

Paoli PA 19301

One MedImmune Way 6700 West Loop South One Franklin Plaza

Gaithersburg 20878 Suite 400 Philadelphia PA 19101 Bellaire TX 77401

1564 33rd Street, NW 9902 Indian Creek Lane

Washington DC 20007 El Cajon CA 92021

University of Florida

P.O. Box 100277

Gainesville FL 32610

University of Florida

P.O. Box 100277

Gainesville FL 32610

3260 Whipple Rd.

Union City CA 94587-1217

University Of Florida 2032 Corte del Nogal

P.O. Box 100277 Suite 120

Gainesville FL 32610 Carlsbad CA 92011

3260 Whipple Rd. 877 Main Street, Suite 402

Union City CA 94587-0700 Boise ID 83702

8260 E. Gelding Drive #104

Scottsdale AZ 85260

8260 East Gelding Drive

Scottsdale AZ 85260

8260 E. Gelding Drive

Scottsdale AZ 85260

26072 Merit Circle

Laguna Hills CA 92653

8125 North Hayden Road

Scottsdaale AZ 85258

75 5th Street, NW.

Atlanta GA 30308

8125 N. Hayden Road

Scottsdale AZ 85258

1300 Gould Dr.

Gainesville GA 30504

8125 N. Hayden Road

Scottsdale AZ 85258

35185

8125 N. Hayden Road

Scottsdale AZ 85258

84 Park Avenue

P. O. Box 968

Flemington NJ 08822

Commander, Us Army Medical Materiel Dev. Activity Ft. Detrick MD 21702

4620 Creekstone Drive

Suite 200

Durham NC 27703

2500 Millbrook Drive

Buffalo Grove IL 60089

26072 Merit Circle

Laguna Hills CA 92653

P. O. Box 2142

WA 6018

P. O. Box 2142 119 Fourth Ave.

Osbourne Park, Western Australia 6017 Needham MA 02494-2725

119 Fourth Avenue

Needham Heights MA 02194

5885 Trinity Parkway

Suite 350

Centreville VA 20120

400 Rella Boulevard, Suite 201

Suffern NY 10901

1950 Lake Park Drive

Smyrna GA 30080

460 Point San Bruno Boulevard 460 Point San Bruno Boulevard Lilly Corporate Center

South San Francisco CA 94080 South San Francisco CA 94080 Indianapolis IN 46285

31337

100 College Road West

Princeton NJ 08540

39233

100 Overlook Center

Suite 200

Princeton NJ 08540

Lilly Corporate Center

Indianapolis IN 46285

35429

100 Overlook Center

Suite 200

Princeton NJ 08540

70 Wood Avenue, South

Iselin NJ 08830

7000 Portage Road One Technology Place

Kalamazoo MI 49001-0199 Rockland MA 02370

35734

460 Point San Bruno Boulevard One Technology Place 100 Longwater Circle

South San Francisco CA 94080 Rockland MA 02370 Norwell MA 02061

31337

2958101

1 DNA Way

South San Francisco CA 94080-4990

2958101

100 Overlook Center One Technology Place One Technology Place

Suite 200 Roackland MA 02370 Rockland MA 02370

Princeton NJ 08540

2958101 37956

7000 Portage Rd.

0633-298-113

Kalamazoo MI 4900136697 0199

7000 Portage Road Lilly Corporate Center 460 Point San Bruno Boulevard

Kalamazoo MI 49001 Indianapolis IN 46285 South San Francisco CA 94080

37097 31844 35779

460 Point San Bruno Boulevard

South San Francisco CA 94080

34290

100 Longwater Circle

Norwell MA 02061

35300

460 Point San Bruno Boulevard

South San Francisco CA 94080

35429

400 Morgan Lane

West Haven CT 06516

400 Morgan Lane

New Haven CT 06516

400 Morgan Lane 5 Research Parkway

West Haven CT 06516 P.O. Box 5100 Wallingford CT 06492

38706

300 Fairfield Road

Wayne NJ 07470

300 Fairfield Road 500 Arcola Road

Wayne NJ 07470 Collegeville PA 19426

33907

5110 Campus Drive

Plymouth Meeting PA 19462

3260 Hillview Avenue

Palo Alto CA 94394

3260 Hillview Avenue

Palo Alto CA 94304

9 Great Valley Parkway

Malvern PA 19355

9 Great Valley Parkway 12276 Wilkins Avenue

Malvern PA 19355 Rockville MD 20852

5, Nahum Hafzadi St. Avenue du Vent des Dames - Z.l. les Paluds Avenue du Vent des Dames - Z.l. les Paluds

Jerusalem 95484

13685 Aubagne

13685 Aubagne

4 Plympton Street

Woburn MA 01801

35788

230 East Grand Ave.

South San Francisco CA 94080-4811

230 East Grand Ave.

South San Francisco CA 94080-4811

90 Park Avenue 90 Park Avenue

New York NY 10016-1389 New York NY 10016-1389

P.O. Box 419056 14555 Avion at Lakeside 100 Banks Avenue 100 Banks Avenue

Saint Louis MO 63141-9056 Chantilly VA 20151 Rockville Centre NY 11570 Rockville Centre NY 11570

32499

227-15 North Conduit Avenue

Laurelton NY 11413

34544

37 Cleveland Lane

P.O. Box 5290

Princeton NJ 08540

4560 Horton Street

Emeryville CA 94608

70 Wood Avenue, South Parke-Davis Pharmaceutical Research Division 1576 Sweet Home Road

Iselin NJ 08830 Ann Arbor MI 481052430

2800 Plymouth Road Amherst NY 14228

2958101

2516 Stockton Boulevard

Sacramento CA 95817

201, 1204 Kensington Road, N.W. 41 Seyon Street 15500 Gallaudet Ave. 15500 Gallaudet Ave. 15500 Gallaudet Ave.

Calgary, Alberta Waltham MA 02453 Silver Spring MD 20905-4176 Silver Spring MD 20905-4176 Silver Spring MD 20905-4176

1550 Gallaudet Ave. 15500 Gallaudet Ave.

Silver Spring MD 20905-4176 Silver Spring MD 20905-4176

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

37561

15500 Gallaudet Ave. 15500 Gallaudet Ave. 205 Buffalo Avenue

Silver Spring MD 20905-4176 Silver Spring MD 20905-4176 Freeport NY 11520

37350 37350

Three Parkway North

Deerfield IL 60015-2548

38805

3 Parkway North Center

Deerfield IL 60015

Lilly Corporate Center

Indianapolis IN 46285

2355 Waukegan Road

Deerfield IL 60015

8 Greenway Plaza

Houston TX 77046

8 Greenway Plaza

Suite 910

Houston TX 77046

Greenway Plaza

Suite 910

Houston TX 77046

8 Greenway Plaza

Suite 910

Houston TX 77046 South San Francisco CA 94080

7000 Shoreline Court

Suite 370

9 Parker

Irvine CA 92618-1605

2161 Delaware Aenue

Santa Cruz CA 95060

1205 Kent Ave. 410 West Harrison

West Lafayette IN 47906 Seattle WA 98119-4007

300 American Road 300 American Road

Morris Plains NJ 07950 Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Road 124 Mount Auburn Street

Morris Plains NJ 07950 Suite 200 North Cambridge MA 02138

210 Carnegie Center

Princeton NJ 08540

67 Winston Churchill Avenue

Brussels

United Drug House

Dublin

2000 Galloping Hill Rd.

Kenilworth NJ 07033

38426

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Rd.

Kenilworth NJ 07033

2000 Galloping Hill Rd.

Kenilworth NJ 07033

36383

P. O. Box 8299

Phildelphia PA 19101-8299

39232

5 Research Parkway

P.O. Box 5100

Wallingford CT 06492 33799

500 Arcola Road

Collegeville PA 19426

32134

27 Maple St.

Milford MA 01757

400 Rella Boulevard, Suite 201

Suffern NY 10901

3 Werner Way 901 Sawyer Rd. Research Park

Round Valley Executive Center Marietta GA 30062 417 Wakara Way

Lebanon NJ 08833

Salt Lake City UT 84108

1990 N.W. 44th Street

Pompano Beach FL 33064

70 Wood Avenue South

Iselin NJ 08830 Washington DC 20006 Washington DC 20006

1825 K Street NW

Suite 1475

1825 K Street, NW

Suite 1475

371 Bel Marin Blvd. University of Vermont

Novato CA 94949 84 Beartown Rd. Underhill VT 05489

9 Great valley Parkway

Malvern PA 19355-1304

Josef-Engert-Str. 9

93053 Regensberg

Technoiparkstrasse 1

Zurich

86 Morris Avenue 11800 Baltimore Avenue, Suite 113

Summit NJ 07901 Beltsville MD 20705

P.O. Box 4914

7 Powder Horn Drive

Warren NJ 07059

7 Powder Horn Dr. 718 Bradford Avenue 718 Bradford Avenue

Warren NJ 07059 Westfield NJ 07090 Westfield NJ 07090

718 Bradford Avenue

Westfield NJ 07090

P.O. Box 4914

7 Powder Horn Drive

Warren NJ 07059

11800 Baltimore Avenue, Suite 113

Beltsville MD 20705

11800 Baltimore Avenue, Suite 113

Beltsville MD 20705

7 Powder Horn Dr. P.O. Box 4914

Warren NJ 07059 7 Powder Horn Srive Warren NJ 07059

86 Morris Avenue

Summit NJ 07901

35992

7 Powder Horn Dr.

Warren NJ 07059

7 Powder Horn Dr. 24128 Bergamo, 64/B Broseta Street

Warren NJ 07059 Bergamo

38862

901 Mariner's Island Blvd

San Mateo CA 94404

901 Mariner's Island Blvd.

San Mateo CA 94404-1593

901 Mariner's Island Blvd.

San Mateo CA 94404-1593

901 Mariner's Blvd., Suite 205

San Mateo CA 94404-1593

3 Bethesda Metro Center

Suite 700

Bethesda MD 20814

500 Iolab Drive One Kendall Square

Claremont CA 91711 Cambridge MA 02139-1562

One Kendall Square

Cambridge MA 02139

36129

9 Great Valley Parkway

PO Box 3026

Malvern PA 19355

3300 Hyland Avenue

Costa Mesa CA 92626

120 Constitution Drive

Menlo Park CA 94025

336 Bollay Drive

Goleta CA 93117

1607 N. Douglas Ave.

Arlington Heights IL 60004

38124

1607 N. Douglas Avenue The University of Texas Health Scienc Center at Da

Arlington Heights IL 60004 5323 Harry Hines Boulevard Dallas TX 75235

38124 32366

920 U.S. Highway 202

Raritan NJ 08869

11 Great Valley Parkway

P. O. Box 3026

Malvern PA 19355

48 Bis, Rue des Belles-Feuilles

75116 Paris

Domino's Farms

24 Frank Lloyd Wright Drive

Ann Arbor MI 48105

Domino's Farms, Lobby L

Ann Arbor MI 48105

Parc Technologique Du Canal-4 800 Gateway Boulevard Drug Regulatory Affairs

31521 Ramonville Saint Agne South San Francisco CA 94080 One Health Plaza East Hanover NJ 07936-1080

Drug Regulatory Affairs 9 Great Valley Parkway

One Health Plaza Malvern PA 19355

East Hanover NJ 07936-1080

35786

Route 202, P.O. Box 300

Raritan NJ 08869-0602

37131

3030 Callan Road

San Diego CA 92121

P.O. Box 65

02101 Espoo

P.O. Box 65

02101 ESPOO King of Prussia PA 19406-2772

35579

2301 Renaissance Blv.

P.O. Box 61540

37799

920 US Highway 202

Raritan NJ 08869

920 U S Highway 202

Raritan NJ 08869

146 Medinah Drive

Blue Bell PA 19422-3212

146 Medinah Drive P.O. Box 16529

Blue Bell PA 19422-3212 Columbus OH 43216

31776

P.O. Box 16529

Columbus OH 43216

P.O. Box 16529

Columbus OH 43216

Level 31, ABN AMRO Tower

88 Phillip Street

Sydney, N.S.W. 2000

3055 Patrick Henry Drive Roslin, Edinburgh 1 DNA Way

Santa Clara CA 95054 EH259PP Scotland South San Francisco CA 94080-4990

Fehlandtstrasse 3

D-20354 Hamburg

68 T.W. Alexander Dr.

P.O. Box 14186

Research Triangle Park NC 27709

37397

340 Kingsland Street

Nutley NJ 07110

35025

3 Forbes Road

Lexington MA 02421

3 Forbes Road

Lexington MA 02421

34 Sherrill Rd.

Marshfield MA 02050

6200 Seaforth Street Division Of Merck And Company

Baltimore MD 21224-6506 West Point PA 19486

31359

Institute of Metabolic Disease

3812 Elm Street

Dallas TX 75226

One MedImmune Way One MedImmune Way

Gaithersburg MD 20878 Gaithersburg MD 20878

One Tower Bridge

100 Front Street, Suite 400

West Conshohocken PA 19428

34320

One MedImmune Way

Gaithersburg MD 20878

One MedImmune Way One MedImmune Way 7929 Westpark Drive, Suite 400

Gaithersburg MD 20878 Gaithersburg MD 20878 Mclean VA 22102

P.O. Box 8050, Station F P.O. Box 8050

Edmonton, Alberta Edmonton, Alberta

P.O. Box 8050 P.O. Box 8050

Edmonton, Alberta Edmonton, Alberta

Box 19255

Johnston RI 02919

5710 Hoover Blvd

Tampa FL 33634

10505 Roselle Street Scheijdelveweg 2 100 Longwater Circle 100 Longwater Circle University of Utah Health Sciences Center

San Diego CA 92121 P.O. Box 43 3214ZG Zuidland

Norwell MA 02061 Norwell MA 02061 Salt Lake City UT 84132-0001

50 North Medical Drive, Room 4R240

3, avenue GeorgeV

75008 Paris

Division of Tishcon Corp

P. O. Box 331

Westbury NY 11590

30 New York Avenue

P.O. Box 331

Westbury NY 11590

30 New York Ave.

PO Box 331

Westbury NY 11590

Grillparzerstrasse 10B

81675 Munich

2 Venture Plaza 4222 Emperor Boulevard, Suite 470

Irvine CA 92618 Durham NC 27703

4222 Emperor Boulevard, Suite 470

Durham NC 27703

100 Longwater Circle

Norwell MA 02061

31673

One Technology Place 500 Iolab Drive 59 Route 10

Rockland MA 02370 Claremont CA 91711 East Hanover NJ 07936-1080

597 Laurier Blvd

Mount St. Hilaire Quebec H7L 4S3

35774

104 Chancellor Matheson Road

Winnipeg, ManitobaR3T 5Y3

2958101

64 Thomas Johnson Drive

Frederick MD 21702

38401

78 Fallon Drive 10901 Granada Lane

North Haven CT 06473 Suite 101 Leawood KS 66211

Paul-Ehrlich Str. 42-44

D-60596 Frankfurt am Main

103 Carnegie Center, Suite 102

Princeton NJ 08540

36063

1800 Concord Pike 666 Sherbrooke Street West 1400 666 Sherbrooke Street West Suite

Wilmington DE 19830-8355

Montreal, Quebec, Suite 1400 Montreal, Quebec H3A 1E7

17 rue des Terreaux 17 rue des Terreaux

CH-1000 Lausanne 9 CH-1000 Lausanne 9

666 Sherbrooke Street West, Suite 1400 Montreal, Quebec 155 Innovation Drive R3T 5Y3

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142 Durham NC 277132280

200 Westpark Corporate Center

4364 South Alston Avenue

105 Digital Drive

Novato CA 94949

Four Parkway North

Deerfield IL 60015

Division of ICI Americas

Wilmington DE 19897

Division of ICI Americas

Wilmington DE 19897

7000 Shoreline Court

South San Francisco CA 94080

7100 Woodbine Avenue, Suite 215

Markham, ON L3R 5J2

Hillcrest

San Diego CA 92103-8450 Rahway NJ 070650900

Merck & Co., Inc.

P. O. Box 2000, RY 32-605

P. O. Box 2000, RY 32-605

Rahway NJ 07065-0900

38996

P. O. Box 2000, RY 32-605

Rahway NJ 07065-0900

99 Hayden Ave.

Lexington MA 02421-7995

4 rue Pierre Fontaine

300 American Rd.

Morris Plains NJ 07950

340 Kingsland Street

Nutley NJ 07110

33774

NIH, Executive Plaza North, Room 7-18 Bethesda MD 20892

5 Moore Drive

Research Triangle Park NC 27709

31855

5 Moore Drive

Research Triangle Park NC 27709

31855

1510 Delp Drive

Kulpsville PA 19443

35458

59 Route 10

East Hanover NJ 07936-1080

37123

12264 El Camino Real

San Diego CA 02130

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