Group B Streptococci (GBS) (S.

agalactiae)

Dr.Aravind

• Group B – Babies (meningitis and Pneumonia) • Facultative anaerobe • Catalase negative • Group specific carbohydrate antigen (B) • β hemolytic • Hippurate + • CAMP + • Bacitracin Resistant • Capsulated – Polysaccharide (III **)

Dr.Aravind

Dr.Aravind

Dr.Aravind

• Epidemiology: • URT and genitourinary tract • New born infection - birth canal, premature membrane rupture, prolonged labor, preterm birth. • Women – Postpartum sepsis risk • Men and women – UTI. • Group III is capsular antigen predominant one in meningitis

Dr.Aravind

• Pathogenesis: • Virulence is associated with a polysaccharide capsule and hydrolytic enzymes (Hemolysins) for tissue . • Clinical Conditions: • Neonatal Meningitis • Neonatal Pneumonia • Septicemia • Postpartum sepsis • UTI • Endometritis
Dr.Aravind

Clinical Features

Meningitis: Fever, Poor feeding, irritability, Bulging Fontanilla, seizers.

Septicemia Pneumonia: Fever, Chills, cough, pleural effusion, consolidation and Xray infiltrations.
Dr.Aravind

Adults: Postpartum sepsis UTI Endometritis

• Diagnosis: • Specimens – CSF or Blood • CAMP + • Hippurate + • Bacitracin resistance • Capsular antigen • Treatment: • Penicillin G • Vancomycin – Penicillin sensitive pts
Dr.Aravind

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