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DRUG STUDY FOR ACUTE HYPERACTIVE APPENDICITIS Ancheta, Pauline Martha De Guzman BSN 301 Mr.

Ferdinand Marco B. Larena, MAN, RN PATIENTS NAME: J. YSLA, 20 YEARS OLD MALE Generic Name Ranitidine Hydrochloride (Brand Name) Zantac Classification Anti-Ulcer Agent Mechanism of Action Inhibits the action of histamine at the H2 receptor sitelocated primarily in gastric parietal cells, resulting ininhibition of gastric acid secretion. Indication Active duodenal and gastric ulcer Maintenance therapy for duodenal or gastric ulcer. Heartburn Pathologic Hypersecretory conditions, such as Zollinger-Ellison syndrome (ZES) Dosage IV : 500mg q8 Nursing Responsibility 1. Assess patient for abdominal pain. Note presence of blood in emesis, stool or gastric aspirate. 2. Remind patient to take oncedaily prescription drug at bedtime for best results. 3. Instruct patient to take without regard to meals because absorption isnt affected by food. 4. Urge patient to avoid cigarette smoking because this may increase gastric acid secretion and

worsen the disease.

Generic Name Tramadol

(Brand Name) Zamadol Zamadol 24hr Zamadol SR Zamadol Melt Zydol, Zydol SR Zydol XL Dromadol SR Larapam SR Mabron

Classification Opioid Analgesics

Mechanism of Action A centrally acting synthetic analgesic compound not chemically related to opioids. Thought to bind to opioid receptors and inhibit reuptake of norepinephrine and serotonin.

Indication For the treatment and prevention of moderate to severe pain.

Dosage IV : 500mg q6

Nursing Responsibility 1. Reasess patients level of pain at least 30 minutes after administration. Monitor bowel and bladder function. Anticipate need for laxative. For better analgesic effect, give drug before the onset of pain. Monitor patient for drug dependence. Withdrawal of symptoms may occur if drug is stopped abruptly. Reduce dosage gradually.

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Generic Name Cefuroxime

(Brand Name) Zinacef

Classification Anti-Infectives

Mechanism of Action Bind to bacterial cell wall membrane causing cell death. Bactericidal Action.

Indication Serious lower respiratory tract infection, UTI, skin or skin structure infections.

Dosage PO: 500 mg/tab q8

Nursing Responsibility 1. Ask for any allergy to penicillins or other cephalosporins before administering the drug. Instruct patient to take oral form with food. Instruct patient to notify prescriber about rash, loose stools, diarrhea, or evidence of superinfection.

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Generic Name Mefenamic Acid

(Brand Name) Ponstan Ponstel

Classification Analgesic Central Nervous System Agent NSAIDS Antipyretic

Mechanism of Action Anthranilic acid derivative. Like ibuprofen inhibits prostaglandin synthesis and affects platelet function.

Indication For the treatment and prevention of moderate to severe pain.

Dosage PO: 500mg/tab q6

Nursing Responsibility 1. Assess patients who develop severe diarrhea and vomiting for dehydration and electrolyte imbalance. Lab tests: With longterm therapy (not recommended) obtain periodic complete blood counts, Hct and

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Hgb, and kidney function tests.