POLYURETHANE POTTING COMPOUND RESIN #199-1474

Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2.0 CD 2009/3 Page 1 of 9

Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME POLYURETHANE POTTING COMPOUND RESIN #199-1474 SYNONYMS CP0128/1, CP0238/1, "Polyurethane Encapulsant", "RS Components" PRODUCT USE Adhesive used for delicate electronic components requiring protection with flexibility and restraint. ■ Part A or Base of a 2 pack. Requires that the two parts be mixed by hand or mixer before use, in accordance with manufacturers directions. Mix only as much as is required. Do not return the mixed material to the original containers. The material when ready for use, i.e. with 2 parts mixed together, CONTAINS free organic isocyanate. Application requires control measures, special precautions and use of personal protective gear. [APMF]. SUPPLIER Company: RS Components Address: Units 30 & 31 Warehouse World 761 Great South Road Penrose Auckland Company: RS Components Address: 25 Pavesi Street Smithfield NSW2164 AUS Telephone: 1300 656 636 Emergency Tel: 1800 039 008 Emergency Tel: 03 9573 3112 Fax: 1300 656 696

Section 2 - HAZARDS IDENTIFICATION STATEMENT OF HAZARDOUS NATURE NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of NOHSC, and the ADG Code. CHEMWATCH HAZARD RATINGS

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POLYURETHANE POTTING COMPOUND RESIN #199-1474
Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2.0 CD 2009/3 Page 2 of 9 Section 2 - HAZARDS IDENTIFICATION

Flammability Toxicity Body Contact Reactivity Chronic SCALE: POISONS SCHEDULE None RISK ■ May produce discomfort of the eyes and respiratory tract*. * (limited evidence). SAFETY ■ Do not breathe gas/fumes/vapour/spray. ■ Wear eye/face protection. ■ In case of contact with eyes rinse with plenty of water and contact Doctor or Poisons Information Centre. Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4

Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS NAME resin, unregulated Section 4 - FIRST AID MEASURES SWALLOWED • For advice, contact a Poisons Information Centre or a doctor. • If swallowed do NOT induce vomiting. • If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration. • Observe the patient carefully. • Never give liquid to a person showing signs of being sleepy or with reduced awareness; i.e. becoming unconscious • Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink. • Seek medical advice. EYE ■ If this product comes in contact with the eyes: • Wash out immediately with fresh running water. • Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. • If pain persists or recurs seek medical attention. • Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. SKIN ■ If skin contact occurs: • Immediately remove all contaminated clothing, including footwear. • Flush skin and hair with running water (and soap if available). • Seek medical attention in event of irritation. INHALED • If fumes or combustion products are inhaled remove from contaminated area. • Lay patient down. Keep warm and rested. continued... CAS RN % 100

Section 5 . . by any means available. • Transport to hospital. Respirator: Section 6 . • BCF (where regulations permit). • Avoid breathing vapours and contact with skin and eyes. • Slight fire hazard when exposed to heat or flame.0 CD 2009/3 Page 3 of 9 Section 4 . NOTES TO PHYSICIAN ■ Treat symptomatically. may emit toxic fumes of carbon monoxide (CO). • Foam. • Cool fire exposed containers with water spray from a protected location. remove containers from path of fire.POLYURETHANE POTTING COMPOUND RESIN #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2. • On combustion. or doctor.ACCIDENTAL RELEASE MEASURES MINOR SPILLS • Remove all ignition sources. FIRE INCOMPATIBILITY ■ Avoid contamination with strong oxidising agents as ignition may result. • Prevent. which may block airway. bag-valve mask device. • Mists containing combustible materials may be explosive. FIRE FIGHTING • Alert Fire Brigade and tell them location and nature of hazard. FIRE/EXPLOSION HAZARD • Combustible. • Heating may cause expansion or decomposition leading to violent rupture of containers. Perform CPR if necessary. • Do not approach containers suspected to be hot. • Apply artificial respiration if not breathing. • Carbon dioxide.FIRE FIGHTING MEASURES EXTINGUISHING MEDIA • Water spray or fog. • If safe to do so. • Clean up all spills immediately. • Use water delivered as a fine spray to control fire and cool adjacent area. where possible.. • Avoid spraying water onto liquid pools. continued. spillage from entering drains or water course. • Wear breathing apparatus plus protective gloves. prior to initiating first aid procedures.FIRST AID MEASURES • Prostheses such as false teeth. should be removed.. • Dry chemical powder. Other combustion products include: carbon dioxide (CO2). Gloves: PVC chemical resistant type. HAZCHEM: None PERSONAL PROTECTION Glasses: Chemical goggles. without delay. preferably with a demand valve resuscitator. • May emit acrid smoke. or pocket mask as trained.

SUITABLE CONTAINER • Metal can or drum • Packaging as recommended by manufacturer. including inhalation. • If contamination of drains or waterways occurs. • Use good occupational work practice. • Contain and absorb spill with sand.POLYURETHANE POTTING COMPOUND RESIN #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2. advise emergency services. by any means available. • When handling. MAJOR SPILLS ■ Minor hazard. • Collect solid residues and seal in labelled drums for disposal. Section 7 . • Prevent concentration in hollows and sumps. • Avoid smoking. • Prevent. Read both MSDS before using. • Alert Fire Brigade and tell them location and nature of hazard. • No smoking. • Contain spill with sand. inert material or vermiculite. • Keep containers securely sealed when not in use. STORAGE INCOMPATIBILITY ■ Avoid storage with oxidisers. • Absorb remaining product with sand. • Check all containers are clearly labelled and free from leaks. • Work clothes should be laundered separately. • Clear area of personnel and move upwind. • Wash area and prevent runoff into drains. DO NOT eat. Personal Protective Equipment advice is contained in Section 8 of the MSDS. continued. • Avoid physical damage to containers. drink or smoke. • Wipe up. • Increase ventilation..HANDLING AND STORAGE PROCEDURE FOR HANDLING • Avoid all personal contact. • Observe manufacturer's storing and handling recommendations. • Wear protective clothing when risk of exposure occurs. naked lights or ignition sources. • Collect recoverable product into labelled containers for recycling. • Always wash hands with soap and water after handling. • Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions. labelled container for waste disposal. • Keep containers securely sealed. store and attach MSDS together. . Refer also to protective measures for the other component used with the product. • Use in a well-ventilated area. • Stop leak if safe to do so. STORAGE REQUIREMENTS • Store in original containers.. earth or vermiculite. naked lights or ignition sources.0 CD 2009/3 Page 4 of 9 Section 6 . earth. earth or vermiculite. • Avoid contact with incompatible materials. • DO NOT enter confined spaces until atmosphere has been checked.ACCIDENTAL RELEASE MEASURES • Control personal contact by using protective equipment. spillage from entering drains or water course. • Place in a suitable. • Wear breathing apparatus plus protective gloves.

• Contact lenses may pose a special hazard. soft contact lenses may absorb and concentrate irritants. continued.. This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience.0 CD 2009/3 Page 5 of 9 Section 7 . • Store away from incompatible materials and foodstuff containers. • Chemical goggles. begin eye irrigation immediately and remove contact lens as soon as practicable. or as required.. PVC. eg. A written policy document. In the event of chemical exposure. dry. • Observe manufacturer's storing and handling recommendations. Lens should be removed at the first signs of eye redness or irritation . • Store in a cool. • Protect containers against physical damage and check regularly for leaks. describing the wearing of lens or restrictions on use. well-ventilated area.HANDLING AND STORAGE • No smoking. [CDC NIOSH Current Intelligence Bulletin 59]. PERSONAL PROTECTION EYE • Safety glasses with side shields.POLYURETHANE POTTING COMPOUND RESIN #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2. Medical and first-aid personnel should be trained in their removal and suitable equipment should be readily available. naked lights or ignition sources.lens should be removed in a clean environment only after workers have washed hands thoroughly. _____________________________________________________ SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS + + + + X + _____________________________________________________ +: May be stored together O: May be stored together with specific preventions X: Must not be stored together Section 8 . OTHER • Overalls.EXPOSURE CONTROLS / PERSONAL PROTECTION EXPOSURE CONTROLS MATERIAL DATA POLYURETHANE POTTING COMPOUND RESIN #199-1474: ■ None assigned for mixture or identified for ingredient(s). Store between 15-30 deg C. HANDS/FEET ■ Wear chemical protective gloves. Wear safety footwear. should be created for each workplace or task. • Eyewash unit. .

low production.) 1. Air contaminants generated in the workplace possess varying "escape" velocities which.2000 f/min. accordingly. Other mechanical considerations. If risk of overexposure exists.10 m/s (500. should be a minimum of 1-2 m/s (200-400 f/min.EXPOSURE CONTROLS / PERSONAL PROTECTION The local concentration of material. evaporating from tank (in still air) aerosols. Velocity generally decreases with the square of distance from the extraction point (in simple cases). 4: Large hood or large air mass in motion Upper end of the range 1: Disturbing room air currents 2: Contaminants of high toxicity 3: High production. heavy use 4: Small hood .0.5 m/s (200. or your Occupational Health and Safety Advisor. quantity and conditions of use determine the type of personal protective equipment required.PHYSICAL AND CHEMICAL PROPERTIES APPEARANCE Yellow to amber liquid with a faint characteristic odour. Correct fit is essential to obtain adequate protection.100 f/min) 0. make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used. welding. producing performance deficits within the extraction apparatus. after reference to distance from the contaminating source. crusher dusts.) Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe.25. spray painting in shallow booths. vapours. high speed wheel generated dusts (released at high initial velocity into zone of very high rapid air motion). drum filling. in turn. abrasive blasting. . low speed conveyer transfers. For further information consult site specific CHEMWATCH data (if available). The air velocity at the extraction fan.5. degreasing etc. gas discharge (active generation into zone of rapid air motion) grinding.POLYURETHANE POTTING COMPOUND RESIN #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2.5. does not mix with water. Within each range the appropriate value depends on: Lower end of the range 1: Room air currents minimal or favourable to capture 2: Contaminants of low toxicity or of nuisance value only 3: Intermittent.5 m/s (50.) for extraction of solvents generated in a tank 2 meters distant from the extraction point.2.500 f/min) 2. wear SAA approved respirator. spray drift. Type of Contaminant: solvent. Provide adequate ventilation in warehouse or closed storage areas. ENGINEERING CONTROLS ■ General exhaust is adequate under normal operating conditions. determine the "capture velocities" of fresh circulating air required to effectively remove the contaminant. intermittent container filling. plating acid fumes.local control only Air Speed: 0. Therefore the air speed at the extraction point should be adjusted. continued.0 CD 2009/3 Page 6 of 9 Section 8 .. fumes from pouring operations.. Section 9 .. conveyer loading.1 m/s (100. pickling (released at low velocity into zone of active generation) direct spray.200 f/min. tumbling. for example.

Sinks in water.04 pH (1% solution): Not applicable Evaporation Rate: Not available Lower Explosive Limit (%): Not available Decomposition Temp (°C): Not available Boiling Range (°C): Not available Solubility in water (g/L): Immiscible Vapour Pressure (kPa): Negligible Relative Vapour Density (air=1): Not available Upper Explosive Limit (%): Not available State: Liquid Melting Range (°C): Not available pH (as supplied): Not applicable Volatile Component (%vol): Not available Flash Point (°C): Not available Autoignition Temp (°C): Not available Section 10 . EYE ■ The liquid may produce eye discomfort and is capable of causing temporary impairment of vision and/or transient eye inflammation.. Molecular Weight: Not applicable Specific Gravity (water=1): 1.. CHRONIC HEALTH EFFECTS ■ Principal routes of exposure are usually by skin contact with the material and inhalation of vapour from the curing material.PHYSICAL AND CHEMICAL PROPERTIES PHYSICAL PROPERTIES Liquid. The liquid is discomforting to the gastro-intestinal tract and may be harmful if swallowed. ulceration.CHEMICAL STABILITY AND REACTIVITY INFORMATION CONDITIONS CONTRIBUTING TO INSTABILITY • Presence of incompatible materials. .POLYURETHANE POTTING COMPOUND RESIN #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2.refer to Section 7 . cracking. abdominal irritation. Ingestion may result in nausea. • Hazardous polymerisation will not occur. Inhalation of vapour may result in nausea. Inhalation hazard is increased at higher temperatures. Section 11 . For incompatible materials . irritation and dermatitis following. SKIN ■ The liquid may produce skin discomfort following prolonged contact.0 CD 2009/3 Page 7 of 9 Section 9 . • Product is considered stable. Defatting and/or drying of the skin may lead to dermatitis.TOXICOLOGICAL INFORMATION POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS SWALLOWED ■ Considered an unlikely route of entry in commercial/industrial environments. INHALED ■ The vapour is mildly discomforting to the upper respiratory tract and lungs.Handling and Storage. pain and vomiting. headache. continued. Prolonged or continuous skin contact with the liquid may cause defatting with drying. Does not mix with water.

• Recycle containers if possible.ECOLOGICAL INFORMATION Refer to data for ingredients. Section 14 . inhalation of vapour. should be avoided by observing good occupational work practice. or dispose of in an authorised landfill. IMDG Section 15 .1474 Persistence: Water/Soil Persistence: Air No data [RS Components] Bioaccumulation Mobility Section 13 . contact with unprotected bare skin. or ingestion in any form. . Ecotoxicity Ingredient Polyurethane Potting Compound Resin #199. TOXICITY AND IRRITATION ■ unless otherwise specified data extracted from RTECS .Register of Toxic Effects of Chemical Substances.REGULATORY INFORMATION POISONS SCHEDULE: None REGULATIONS No data for Polyurethane Potting Compound Resin #199-1474 (CW: 4523-70) continued. • Bury or incinerate residue at an approved site. • Consult State Land Waste Authority for disposal.TRANSPORTATION INFORMATION HAZCHEM: None (ADG6) NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS: UN. TOXICITY Oral (rat) LD50: 10000 mg/kg [RS Components] IRRITATION Section 12 .TOXICOLOGICAL INFORMATION As with any chemical product. IATA..DISPOSAL CONSIDERATIONS • Recycle wherever possible or consult manufacturer for recycling options.POLYURETHANE POTTING COMPOUND RESIN #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2.. mist or dust in work place atmosphere. Persistence & Degradability: Not readily degradable. which follows: POLYURETHANE POTTING COMPOUND RESIN #199-1474: Mobility: May spread quite readily along the ground in quantity.0 CD 2009/3 Page 8 of 9 Section 11 .

POLYURETHANE POTTING COMPOUND RESIN #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-70 Version No:2. review or criticism.net/references.chemwatch.OTHER INFORMATION ■ Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references. no part may be reproduced by any process without written permission from CHEMWATCH. ■ The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. as permitted under the Copyright Act.0 CD 2009/3 Page 9 of 9 Section 16 . A list of reference resources used to assist the committee may be found at: www. Apart from any fair dealing for the purposes of private study. Risks may be determined by reference to Exposures Scenarios. Issue Date: 19-Feb-2008 Print Date: 5-Feb-2010 This is the end of the MSDS. TEL (+61 3) 9572 4700. This document is copyright. frequency of use and current or available engineering controls must be considered. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. . research. Scale of use.

POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. . ■ Hardener or Part B of a 2 pack epoxy system. "Polyurethane Encapsulant".HAZARDS IDENTIFICATION STATEMENT OF HAZARDOUS NATURE HAZARDOUS SUBSTANCE. CHEMWATCH HAZARD RATINGS Flammability Toxicity Body Contact Reactivity Chronic SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 continued. CP0238/1.0 CD 2009/3 Page 1 of 16 Section 1 . According to the Criteria of NOHSC. SUPPLIER Company: RS Components Address: Units 30 & 31 Warehouse World 761 Great South Road Penrose Auckland Company: RS Components Address: 25 Pavesi Street Smithfield NSW2164 AUS Telephone: 1300 656 636 Emergency Tel: 1800 039 008 Emergency Tel: 03 9573 3112 Fax: 1300 656 696 Section 2 .CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME POLYURETHANE POTTING COMPOUND HARDENER #199-1474 SYNONYMS CP0128/1. "RS Components" PRODUCT USE Adhesive used for delicate electronic components requiring protection with flexibility and restraint. and the ADG Code. NON-DANGEROUS GOODS...

ONLY IF CONSCIOUS. REFER FOR MEDICAL ATTENTION. ■ To clean the floor and all objects contaminated by this material use water and detergent. ■ Keep container in a well ventilated place.diphenylmethane diisocyanate (MDI) Section 4 ..POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. • If the services of a medical officer or medical doctor are readily available.FIRST AID MEASURES SWALLOWED • For advice. ■ May cause SENSITISATION by inhalation and skin contact. WHERE POSSIBLE. the patient should be placed in his/her care and a copy of the MSDS should be provided. ■ Keep container tightly closed. Further action will be the responsibility of the medical specialist. ■ Skin contact may produce health damage*. (show this container or label).obtain special instructions before use. CAS RN 101-68-8 % 100 continued. contact a Poisons Information Centre or a doctor. ■ Use only in well ventilated areas. • IF SWALLOWED. ■ Irritating to eyes respiratory system and skin. ■ Avoid exposure .. WITHOUT DELAY. ■ Keep away from food drink and animal feeding stuffs. ■ May possibly affect fertility*. qualified first-aid personnel should treat the patient following observation and employing supportive measures as indicated by the patient's condition. ■ Cumulative effects may result following exposure*. • In the mean time. Section 3 . SAFETY ■ Do not breathe gas/fumes/vapour/spray. • For advice. NOTE: Wear a protective glove when inducing vomiting by mechanical means. • If medical attention is not available on the worksite or surroundings send the patient to a hospital together with a copy of the MSDS. • Lean patient forward or place on left side (head-down position if possible) to maintain open airway and prevent aspiration. * (limited evidence). Where Medical attention is not immediately available or where the patient is more than 15 minutes from a hospital or unless instructed otherwise: • Induce vomiting with fingers down the back of the of the throat.0 CD 2009/3 Page 2 of 16 Section 2 . contact a Poisons Information Centre or a doctor. .COMPOSITION / INFORMATION ON INGREDIENTS NAME 4.HAZARDS IDENTIFICATION POISONS SCHEDULE S6 RISK ■ Harmful by inhalation. ■ In case of contact with eyes rinse with plenty of water and contact Doctor or Poisons Information Centre. ■ If swallowed IMMEDIATELY contact Doctor or Poisons Information Centre. 4' .

LARGE FIRES • Alcohol stable foam. • Some cross-sensitivity occurs between different isocyanates. such as decreased FEV1. • Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. • Clinical symptoms of exposure involve mucosal irritation of respiratory and gastrointestinal tracts. or for at least 15 minutes. may not represent sensitivity. • Alcohol stable foam. Perform CPR if necessary. pain vesiculation) and gastrointestinal disturbances occur soon after exposure. They induce smooth muscle contraction which leads to bronchoconstrictive episodes. • Pulmonary symptoms include cough. systemic analgesics and topical antibiotics (Sulamyd) may be used for corneal abrasions. • Transport to hospital or doctor without delay. where possible. or pocket mask as trained. Carbon dioxide. • Apply artificial respiration if not breathing. without delay. Section 5 .. magnesium citrate) may be useful for ingestion. substernal pain and dyspnoea. [Karol & Jin.FIRE FIGHTING MEASURES SMALL FIRES • Dry chemical powder. burning. NOTES TO PHYSICIAN ■ For sub-chronic and chronic exposures to isocyanates: • This material may be a potent pulmonary sensitiser which causes bronchospasm even in patients without prior airway hyperreactivity. Markedly symptomatic patients should receive oxygen. which may block airway. • Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. • Seek medical attention in event of irritation. • Presents additional hazard when fire fighting in a confined space.. • Small quantities of water in contact with hot liquid may react violently with generation of a large volume of rapidly expanding hot sticky semi-solid foam. • Treatment for asthma includes inhaled sympathomimetics (epinephrine [adrenalin]. continued. should be removed. skin inflammation (erythema. including footwear. • Noncardiogenic pulmonary edema and bronchospasm are the most serious consequences of exposure. Frontiers in Molecular Toxicology. • Lay patient down. • Conjunctival irritation. terbutaline) and steroids. • Prostheses such as false teeth. pp 56-61. • There is no effective therapy for sensitised workers. INHALED • If fumes or combustion products are inhaled remove from contaminated area. Acute changes in lung function. • Mydriatics. 1992].POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. • Continue flushing until advised to stop by the Poisons Information Centre or a doctor. • Flush skin and hair with running water (and soap if available). • Activated charcoal (1 g/kg) and a cathartic (sorbitol. bag-valve mask device. Medical Toxicology] NOTE: Isocyanates cause airway restriction in naive individuals with the degree of response dependant on the concentration and duration of exposure. Keep warm and rested. preferably with a demand valve resuscitator.FIRST AID MEASURES EYE ■ If this product comes in contact with the eyes: • Immediately hold eyelids apart and flush the eye continuously with running water. or • Flooding quantities of water only. or doctor. SKIN ■ If skin contact occurs: • Immediately remove all contaminated clothing. ventilatory support and an intravenous line. • DO NOT use water. [Ellenhorn and Barceloux. . • Transport to hospital. prior to initiating first aid procedures.0 CD 2009/3 Page 3 of 16 Section 4 .

DO NOT approach containers suspected to be hot. Such reactions in the absence of solvents often occur with explosive violence. Wear protective clothing. and peroxides can cause vigorous releases of heat. continued. Acids and bases initiate polymerisation reactions in these materials. ketones. HAZCHEM: None Personal Protective Equipment Gas tight chemical resistant suit. • Isocyanates will attack and embrittle some plastics and rubbers.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. • Moderate fire hazard when exposed to heat or flame.. phenols. by any means available. • Wear full body protective clothing with breathing apparatus. Gas generation may pressurise drums to the point of rupture. Foaming in confined spaces may produce pressure in confined spaces or containers. • Some isocyanates react with water to form amines and liberate carbon dioxide. • Isocyanates easily form adducts with carbodiimides. alkali metals. impervious gloves and safety glasses.0 CD 2009/3 Page 4 of 16 Section 5 . reacting exothermically to release toxic gases. Alert Fire Brigade and tell them location and nature of hazard. Shut off all possible sources of ignition and increase ventilation. Collect residues and place in labelled plastic containers with vented lids. aldehydes.ACCIDENTAL RELEASE MEASURES MINOR SPILLS ■ Clean up all spills immediately. spillage from entering drains or water courses. • Prevent. Section 6 . mercaptans. remove containers from path of fire. • When heated to high temperatures decomposes rapidly generating vapour which pressures and may then rupture containers with release of flammable and highly toxic isocyanate vapour. • Combustion yields traces of highly toxic hydrogen cyanide HCN.. • Burns with acrid black smoke and poisonous fumes. hydrides. alcohols. isothiocyanates. If safe to do so. ketenes. alcohols and detergent solutions. • Do NOT reseal container if contamination is expected • Open all containers with care • Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. strong bases. This reaction may also generate large volumes of foam and heat. Contain and absorb spill with sand. earth. Reactions with amines. strong oxidisers.FIRE FIGHTING MEASURES • Cooling with flooding quantities of water reduces this risk. Sweep up. plus toxic nitrogen oxides NOx and carbon monoxide. Avoid spraying water onto liquid pools. FIRE INCOMPATIBILITY • Avoid any contamination of this material as it is very reactive and any contamination is potentially hazardous. • Isocyanates and thioisocyanates are incompatible with many classes of compounds. Cool fire exposed containers with water spray from a protected location. FIRE/EXPLOSION HAZARD • Combustible. or with substrates containing activated CC or CN bonds. • Avoid reaction with water. Avoid contact with skin and eyes. • Water spray or fog may cause frothing and should be used in large quantities. FIRE FIGHTING ■ Clear area of personnel. inert material or vermiculite. .

• Wear full body protective clothing with breathing apparatus. Contain and absorb spill with sand. Use good occupational work practice. Section 7 . Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions are maintained. until atmosphere has been checked.1% Toxic (T) >= 3.e. Use in a well-ventilated area. i. Clear area of personnel.5% else >= 10% where percentage is percentage of ingredient found in the mixture Personal Protective Equipment advice is contained in Section 8 of the MSDS. No smoking or naked lights within area.contain spillage.ACCIDENTAL RELEASE MEASURES MAJOR SPILLS ■ Pollutant . • Alert Fire Brigade and tell them location and nature of hazard.0% R51 >= 2. Wash spill area with detergent and water.2mg/m³ American Industrial Hygiene Association (AIHA) Ingredients considered according to the following cutoffs Very Toxic (T+) >= 0.. . transient adverse effects without perceiving a clearly defined odour is: 4. Always wash hands with soap and water after handling. • Avoid cross contamination between the two liquid parts of product (kit). • Prevent. continued. DO NOT USE WATER OR NEUTRALISING AGENTS INDISCRIMINATELY ON LARGE SPILLS.25% Corrosive (C) >= 5. by any means available.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. Avoid contact with moisture.4'-diphenylmethane diisocyanate (MDI) 0. Collect residues and seal in labelled drums for disposal. Wear protective clothing and gloves when handling containers. Stop leak if safe to do so. spillage from entering drains or water course.HANDLING AND STORAGE PROCEDURE FOR HANDLING ■ Handle and open container with care.0 CD 2009/3 Page 5 of 16 Section 6 .4'-diphenylmethane diisocyanate (MDI) 2mg/m³ other than mild.0% R50 >= 0. to keep exposures below required standards. earth. inert material or vermiculite. EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG) The maximum airborne concentration below which it is believed that nearly all individuals could be exposed for up to one hour WITHOUT experiencing or developing life-threatening health effects is: 4. Shut off all possible sources of ignition and increase ventilation. Local exhaust ventilation may be required for safe working. Avoid physical damage to containers. Avoid breathing vapours and contact with skin and eyes.4'-diphenylmethane diisocyanate (MDI) 25mg/m³ irreversible or other serious effects or symptoms which could impair an individual's ability to take protective action is: 4. otherwise PPE is required. Work clothes should be laundered separately..

Avoid contamination of water. basements or areas where vapours may be trapped. Store between 15 and 30 deg. • Store in original containers in approved flame-proof area. _____________________________________________________ SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS + X + X X + _____________________________________________________ +: May be stored together O: May be stored together with specific preventions X: Must not be stored together Section 8 . STORAGE INCOMPATIBILITY ■ Avoid storage with oxidisers. • Open all containers with care. • Avoid contamination with water. polymerisation with gelation and evolution of heat (exotherm) may occur. pressurises containers with even drum rupture resulting. • Keep containers securely sealed.EXPOSURE CONTROLS / PERSONAL PROTECTION EXPOSURE CONTROLS Source ___________ Australia Exposure Standards Material ___________ 4. • This excess heat may generate toxic vapour. C. • No smoking. dry well ventilated area. SUITABLE CONTAINER • Metal can or drum • Packaging as recommended by manufacturer.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2..diphenylmethane diisocyanate (MDI) Revised IDLH Value (mg/m3) 75 Revised IDLH Value (ppm) continued. naked lights.07 Notes _______ Sen EMERGENCY EXPOSURE LIMITS Material 4.0 CD 2009/3 Page 6 of 16 Section 7 . . • Check all containers are clearly labelled and free from leaks. • Material reacts with water and generates gas. all (asNCO)) TWA mg/m³ _______ 0. heat or ignition sources. alkalies and detergent solutions. • Observe manufacturer's storing and handling recommendations.diphenylmethane diisocyanate (MDI) (Isocyanates. foodstuffs. feed or seed. • Store away from incompatible materials in a cool. 4' ..02 STEL mg/m³ _______ 0. • Protect containers against physical damage and check regularly for leaks. 4' .HANDLING AND STORAGE • If two part products are mixed or allowed to mix in proportions other than manufacturer's recommendation. depressions. STORAGE REQUIREMENTS • Keep dry. • DO NOT reseal container if contamination is suspected. • DO NOT store in pits.

[CDC NIOSH Current Intelligence Bulletin 59].0 CD 2009/3 Page 7 of 16 Section 8 .EXPOSURE CONTROLS / PERSONAL PROTECTION MATERIAL DATA POLYURETHANE POTTING COMPOUND HARDENER #199-1474: Not available 4. MDI) Odour Threshold Value: 0. these afford face protection.4'-DIPHENYLMETHANE DIISOCYANATE (MDI): ■ for diphenylmethane diisocyanate (methylene bisphenyl isocyanate. • DO NOT use solvent to clean the skin . • Safety footwear or • Rubber boots.003 ppm appear to have no acute or chronic effect on pulmonary function. goggles must be properly fitted • Full face shield (20 cm. should be created for each workplace or task. • Neoprene rubber gloves or • Butyl rubber gloves or • PVC gloves. Ceiling values recommended by NIOSH and OSHA are synonymous with normal excursions allowable for exposures to the TLV-TWA (in excess of 3 x TLV-TWA for no more than a total of 30 minutes during a work day but in any case not exceeding 5 x TLV-TWA). PERSONAL PROTECTION EYE • Safety glasses with unperforated side shields may be used where continuous eye protection is desirable. as in laboratories. Medical and first-aid personnel should be trained in their removal and suitable equipment should be readily available. spectacles are not sufficient where complete eye protection is needed such as when handling bulk-quantities. or if the material may be under pressure • Chemical goggles. Lens should be removed at the first signs of eye redness or irritation . • Eyewash unit. DO NOT return unused product to containers. • Alternatively a gas mask may replace splash goggles and face shields.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. A written policy document.. Individuals who may be hypersusceptible or otherwise unusually responsive to exposure to certain industrial chemicals may not adequately protected from adverse health effects caused by MDI at the recommended TLV-TWA. . This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience.39 ppm IDLH Level: 10 mg/m3 Mean MDI exposures of less than 0. Exposure at or below the recommended value is thought to protect the worker against pulmonary function decrements as well as to minimise the potential for respiratory tract sensitisation. In the event of chemical exposure. • Skin cleansing cream. OTHER • Overalls. begin eye irrigation immediately and remove contact lens as soon as practicable. soft contact lenses may absorb and concentrate irritants. MDI produces identical toxicological responses to those produced by TDI and the recommended TLV-TWA is identical for the two isocyanates.. HANDS/FEET • DO NOT use skin cream unless necessary and then use only minimum amount. • Contact lenses may pose a special hazard. continued. 8 in minimum) may be required for supplementary but never for primary protection of eyes. • Isocyanate vapour may be absorbed into skin cream and this increases hazard. where there is a danger of splashing.lens should be removed in a clean environment only after workers have washed hands thoroughly.whenever there is a danger of the material coming in contact with the eyes. describing the wearing of lens or restrictions on use.

For further information consult site specific CHEMWATCH data (if available). heavy use 4: Small hood. Therefore the air speed at the extraction point should be adjusted. wear approved respirator. ENGINEERING CONTROLS ■ Use in a well-ventilated area. pickling (released at low velocity into zone of active generation) direct spray.) 2. Refer to protective measures for other components used with this product. Local exhaust ventilation and full face air supplied breathing apparatus (hood or helmet type) are required.. quantity and conditions of use determine the type of personal protective equipment required. welding.200 f/min. vapours. 3: Intermittent. producing performance deficits within the extraction apparatus.. Avoid breathing dust when sanding. Air contaminants generated in the workplace possess varying "escape" velocities which. or your Occupational Health and Safety Advisor.100 f/min. 4: Large hood or large air mass in motion Upper end of the range 1: Disturbing room air currents 2: Contaminants of high toxicity 3: High production. evaporating from tank (in still air). after reference to distance from the contaminating source. Type of Contaminant: solvent. high speed wheel generated dusts (released at high initial velocity into zone of very high rapid air motion). .local control only Air Speed: 0. If dust inhalation risk exists continued.5.5 m/s (50. conveyer loading. spray painting in shallow booths. crusher dusts.) 0. spray drift. tumbling.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2.EXPOSURE CONTROLS / PERSONAL PROTECTION The local concentration of material. Supplied-air type respirator may be required in special circumstances. Other mechanical considerations. intermittent container filling. low production. in turn. Note: Organic vapour respirators are not protection for sensitised workers. aerosols. Local exhaust ventilation usually required.5 m/s (200. An approved self contained breathing apparatus (SCBA) may be required in some situations.) 1.10 m/s (500.0. Within each range the appropriate value depends on: Lower end of the range 1: Room air currents minimal or favourable to capture 2: Contaminants of low toxicity or of nuisance value only.25.2000 f/min. degreasing etc. The air velocity at the extraction fan.1 m/s (100. Spraying must be carried out in conditions conforming to local State regulations. Correct fit is essential to obtain adequate protection. abrasive blasting.0 CD 2009/3 Page 8 of 16 Section 8 . accordingly. Correct fit is essential to ensure adequate protection. fumes from pouring operations. Unprotected personnel must vacate the spraying area. for example..) Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. low speed conveyer transfers. Provide adequate ventilation in warehouse or closed storage area. determine the "capture velocities" of fresh circulating air required to effectively remove the contaminant. Velocity generally decreases with the square of distance from the extraction point (in simple cases). make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used. drum filling.500 f/min. gas discharge (active generation into zone of rapid air motion) grinding.5. should be a minimum of 1-2 m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from the extraction point.2. If risk of overexposure exists. plating acid fumes.

PHYSICAL AND CHEMICAL PROPERTIES APPEARANCE Yellow to amber liquid with a faint characteristic odour. approved dust respirator. .04 pH (1% solution): Not applicable Evaporation Rate: Not available Lower Explosive Limit (%): Not available Decomposition Temp (°C): Not available Boiling Range (°C): Not available Solubility in water (g/L): Immiscible Vapour Pressure (kPa): Negligible Relative Vapour Density (air=1): Not available Upper Explosive Limit (%): Not available State: Liquid Melting Range (°C): Not available pH (as supplied): Not applicable Volatile Component (%vol): Not available Flash Point (°C): Not available Autoignition Temp (°C): Not available continued. Type of Contaminant direct spray. in turn. low production. make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used. Therefore the air speed at the extraction point should be adjusted.EXPOSURE CONTROLS / PERSONAL PROTECTION wear S. for example.A. crusher dusts. spray painting in shallow booths.500 f/min. Air contaminants generated in the workplace possess varying "escape" velocities which.) Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. determine the "capture velocities" of fresh circulating air required to effectively remove the contaminant. does not mix with water..) for extraction of solvents generated by spraying at a point 2 meters distant from the extraction point. Other mechanical considerations.local control only Air Speed 1.5 m/s (200. conveyer loading. 4: Large hood or large air mass in motion Upper end of the range 1: Disturbing room air currents 2: Contaminants of high toxicity 3: High production. Molecular Weight: Not applicable Specific Gravity (water=1): 1. after reference to distance from the contaminating source. Partly soluble in organic solvents. Does not mix with water. accordingly.0 CD 2009/3 Page 9 of 16 Section 8 .2. heavy use 4: Small hood. Sinks in water. producing performance deficits within the extraction apparatus. Velocity generally decreases with the square of distance from the extraction point (in simple cases). PHYSICAL PROPERTIES Liquid. If possible use wet sanding techniques to avoid generating dust. 3: Intermittent.. The air velocity at the extraction fan.A. drum filling. Section 9 .POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. should be a minimum of 4-10 m/s (800-2000 f/min. gas discharge (active generation into zone or rapid air motion) Within each range the appropriate value depends on: Lower end of the range 1: Room air currents minimal or favourable to capture 2: Contaminants of low toxicity or of nuisance value only.

. skin sensitisation. ataxia. INHALED ■ The vapour/mist may be highly irritating to the upper respiratory tract and lungs. The vapour is discomforting to the eyes. The significance of the contact allergen is not simply determined by its sensitisation potential: the distribution of the substance and the opportunities for contact with it are equally important. ■ Contact allergies quickly manifest themselves as contact eczema. Inhalation hazard is increased at higher temperatures. euphoria. with possible permanent impairment of vision. involve antibody-mediated immune reactions. . The liquid is highly discomforting and harmful if swallowed. For incompatible materials . Storage in unsealed containers. Pulmonary sensitisation may produce asthmatic reactions ranging from minor breathing difficulties to severe allergic attacks. are continued. contact urticaria. Gastrointestinal disturbances are characterised by nausea and vomiting. Sensitized people can react to very low doses.0 CD 2009/3 Page 10 of 16 Section 10 . anxiety neurosis. insomnia. • Presence of elevated temperatures. Ingestion may result in nausea. itching. substances are noteworthy if they produce an allergic test reaction in more than 1% of the persons tested. From a clinical point of view. Bare unprotected skin should not be exposed to this material. if not promptly and adequately treated. A weakly sensitising substance which is widely distributed can be a more important allergen than one with stronger sensitising potential with which few individuals come into contact. The pathogenesis of contact eczema involves a cell-mediated (T lymphocytes) immune reaction of the delayed type. abdominal irritation. Sensitisation may result in allergic dermatitis responses including rash.g. Section 11 . Allergic reactions which develop in the respiratory passages as bronchial asthma or rhinoconjunctivitis. Repeated or prolonged exposure to irritants may produce conjunctivitis. Corneal injury may develop. depression and paranoia.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. The vapour is toxic and may be fatal if inhaled. this may occur following a single acute exposure or may develop without warning for several hours after exposure.CHEMICAL STABILITY AND REACTIVITY INFORMATION CONDITIONS CONTRIBUTING TO INSTABILITY ■ Presence of water and • Presence of incompatible materials. EYE ■ The liquid is highly discomforting to the eyes and is capable of causing pain and severe conjunctivitis. Toxic effects may result from skin absorption. the response may be severe enough to produce bronchitis and pulmonary oedema. SKIN ■ The material is moderately discomforting to the skin and may cause allergic skin reactions. more rarely as urticaria or Quincke's oedema. The material may produce moderate eye irritation leading to inflammation. Other allergic skin reactions.TOXICOLOGICAL INFORMATION POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS SWALLOWED ■ Considered an unlikely route of entry in commercial/industrial environments. hives or swelling of extremities. pain and vomiting.. and should not be allowed to work in situations allowing exposure to this material.Handling and Storage. e. Continued exposure of sensitised persons may lead to possible long term respiratory impairment.refer to Section 7 . Possible neurological symptoms arising from isocyanate exposure include headache. Inhalation of vapour may aggravate a pre-existing respiratory condition.

itching. Skin sensitisation is possible and may result in allergic dermatitis responses including rash. this may occur following a single acute exposure or may develop without warning after a period of tolerance. A respiratory response may occur following minor skin contact.. even sudden loss of consciousness. .4'-dihydroxydiphenyl oxide analogues have been investigated as potential oestrogen receptor/ anti-tumour drug carriers in the development of a class of therapeutic drugs called "cytostatic hormones". there appears to be little or no difference between aromatic and aliphatic diisocyanates as toxicants. Based upon a very limited data set. Based on repeated dose studies in animals by the inhalation route. Sensitisation may give severe responses to very low levels of exposure. gasping and severe distress. In addition to the allergen-specific potential for causing respiratory sensitisation. Isocyanate-containing vapours/ mists may cause inflammation of eyes and nasal passages. and pulmonary oedema. allergic bronchial asthma and atopic eczema (neurodermatitis) which is associated with increased IgE synthesis. TOXICITY Oral (rat) LDLo: 9200 mg/kg IRRITATION Skin (rabbit): 500 mg /24 hours Inhalation (rat) LC50: 178 mg/m³/4h Dermal Sensitiser * Oral (mouse) LD50: 2200 mg/kg Respiratory Sensitiser (g. gasping. They may be genetically determined or acquired. anxiety neurosis. Factors which increase the sensitivity of the mucosa may play a role in predisposing a person to allergy.0 CD 2009/3 Page 11 of 16 Section 11 . from coughing and minor breathing difficulties to bronchitis with wheezing. Possible neurological symptoms arising from isocyanate exposure include headache. in situations where exposure may occur. insomnia. Most members of the continued. Oestrogenic activity is induced with 1 to 100 mg/kg of these substances. Respiratory sensitisation may result in allergic/asthma like responses. Particular attention is drawn to so-called atopic diathesis which is characterised by an increased susceptibility to allergic rhinitis. the exposure period and the genetically determined disposition of the exposed person are likely to be decisive. There is also evidence that both aromatic and aliphatic diisocyanates are acutely toxic via the inhalation route. CHRONIC HEALTH EFFECTS ■ Principal routes of exposure are usually by inhalation of vapour and skin contact/absorption. Pulmonary sensitisation may produce asthmatic reactions ranging from minor breathing difficulties to severe allergic attacks. TOXICITY AND IRRITATION ■ unless otherwise specified data extracted from RTECS . depression and paranoia. Isocyanate vapours/mists are irritating to the upper respiratory tract and lungs.Register of Toxic Effects of Chemical Substances. both aromatic and aliphatic diisocyanates appear to be of high concern for pulmonary toxicity at low exposure levels.Register of Toxic Effects of Chemical Substances. In addition. it appears that diisocyanate prepolymers exhibit the same respiratory tract effects as the monomers in repeated dose studies. Onset of symptoms may be immediate or delayed for several hours after exposure.TOXICOLOGICAL INFORMATION mostly the result of reactions of the allergen with specific antibodies of the IgE class and belong in their reaction rates to the manifestation of the immediate type. ataxia. hives and swelling of extremities. for example. TOXICITY Oral (rat) LD50: >2000 mg/kg [RS Components] IRRITATION 4. Unprotected or sensitised persons should not be allowed to work in situations allowing exposure to this material. euphoria. Immunologically the low molecular weight substances become complete allergens in the organism either by binding to peptides or proteins (haptens) or after metabolism (prohaptens). the amount of the allergen.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2.4'-DIPHENYLMETHANE DIISOCYANATE (MDI): ■ unless otherwise specified data extracted from RTECS . Sensitised people can react to very low levels of airborne isocyanates. the response may be severe enough to produce bronchitis with wheezing. there are insufficient data available to make any major distinctions between polymeric (<1000 MW) and monomeric diisocyanates.pig) * Dermal (rabbit) LD50: >6200 mg/kg * [* = Bayer CCINFO 2133615] Oral (Rat) LD50: 9200 mg/kg ■ for diisocyanates: In general. during infections or exposure to irritant substances.. A series of 4. Gastrointestinal disturbances are characterised by nausea and vomiting.

Diisocyanates are moderate to strong dermal sensitisers in animal studies. In the absence of more human data. it would be prudent at this time to assume that both aromatic and aliphatic diisocyanates are respiratory sensitisers. it would be prudent at this time to assume that both aromatic and aliphatic diisocyanates are respiratory sensitisers. Respiratory and Dermal Sensitization: Based on the available toxicity data in animals and epidemiologic studies of humans. Though the oral route is not an expected route of exposure to humans. HDI and possibly isophorone diisocyanate (IPDI). Two case reports of human exposure to IPDI by inhalation suggest IPDI is a respiratory sensitiser in humans.4'-methylenediphenyl diisocyanate (MDI) and 53% higher molecular weight oligomers. increased bronchoconstriction reaction to histamine challenges. wheezing and coughing. was found to be corrosive to the skin in guinea pigs.TOXICOLOGICAL INFORMATION diisocyanate category have not been tested for carcinogenic potential. DADI was found to be carcinogenic in rats. Key criteria for the diagnosis of RADS include the absence of preceding respiratory disease..026 mg/L. it is premature to make any generalizations about the carcinogenic potential of aromatic versus aliphatic diisocyanates. Though the aromatic diisocyanates tested positive and the one aliphatic diisocyanate tested negative in one species. 4'-diisocyanate (dianisidine diisocyanate. aliphatic hexamethylene diisocyanate (HDI) was found not to be carcinogenic in a two year repeated dose study in rats by the inhalation route. Other allergic skin reactions. are reported to be associated with respiratory sensitization in humans.g. more rarely as urticaria or Quincke's oedema. A weakly sensitising substance which is widely distributed can be a more important allergen than one with stronger sensitising potential with which few individuals come into contact. There is also evidence that both aromatic and aliphatic diisocyanates are acutely toxic via the inhalation route Oncogenicity: Most members of the diisocyanate category have not been tested for carcinogenic potential.0 CD 2009/3 Page 12 of 16 Section 11 . and pulmonary adenocarcinoma in one male in the high dose group. One chemical.3'-dimethoxy-benzidine-4. DADI) were found to be carcinogenic in rodents. lungs and mediastinal lymph nodes. In view of the information from case reports in humans. The experimental animal data available on prepolymeric diisocyanates show similar adverse effects at levels that range from 0. MDI and dicyclohexylmethane-4. in a non-atopic individual. TDI induced a statistically significant increase in the incidence of liver tumors in rats and mice as well as dose-related hemangiosarcomas of the circulatory system and has been classified by the Agency as a B2 carcinogen. Symptoms resulting from occupational exposure to HDI include shortness of breath. with a statistically increase in the incidence of pancreatic tumors observed. aromatic toluene diisocyanate (TDI) and 3. For monomers. HDI has not been tested in mice by the inhalation route. effects on the respiratory tract (lungs and nasal cavities) were observed in animal studies at exposure concentrations of less than 0.. Aliphatic diisocyanates are generally not active in animal models for respiratory sensitization. irrespective of whether the challenge compound was an aliphatic or aromatic diisocyanate. with abrupt onset of continued. However. However. hydrogenated MDI (1. Contact allergies quickly manifest themselves as contact eczema.005 mg/L.002 mg/L to 0. Commercially available Poly-MDI was tested in a 2-year inhalation study in rats. it should be noted that in two year repeated dose studies by the oral route.4'-diisocyanate (HMDI) suggest cross-reactivity with the other diisocyanates.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. Dermal Irritation: Skin irritation studies performed on rabbits and guinea pigs indicate no difference in the effects of aromatic versus aliphatic diisocyanates. Pulmonary adenomas were found in 6 males and 2 females. Asthma-like symptoms may continue for months or even years after exposure to the material ceases. but not in mice. There seems to be little or no difference in the level of reactivity between aromatic and aliphatic diisocyanates. substances are noteworthy if they produce an allergic test reaction in more than 1% of the persons tested.1-methylenebis-4-isocyanatocyclohexane). involve antibody-mediated immune reactions. This may be due to a non-allergenic condition known as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high levels of highly irritating compound. The tested material contained 47% aromatic 4. Interim sacrifices at one year showed that males and females in the highest dose group (6 mg/m3) had treatment related histological changes in the nasal cavity. From a clinical point of view. HDI. The incidence and severity of degeneration and basal cell hyperplasia of the olfactory epithelium and Bowman's gland hyperplasia were increased in males at the mid and high doses and in females at the high dose following the two year exposure period. . The significance of the contact allergen is not simply determined by its sensitisation potential: the distribution of the substance and the opportunities for contact with it are equally important. Skin irritation studies performed on rabbits and guinea pigs indicate no difference in the effects of aromatic versus aliphatic diisocyanates. Diisocyanates are moderate to strong dermal sensitisers in animal studies. e. The level of irritation ranged from slightly to severely irritating to the skin. asthmatic reactions. The pathogenesis of contact eczema involves a cell-mediated (T lymphocytes) immune reaction of the delayed type. aromatic diisocyanates such as TDI and MDI are strong respiratory sensitisers. contact urticaria. Studies in both human and mice using TDI.

Skin sensitisation is possible and may result in allergic dermatitis responses including rash. Isocyanate vapours/mists are irritating to the upper respiratory tract and lungs. hives and swelling of extremities. They may be genetically determined or acquired. Allergic reactions which develop in the respiratory passages as bronchial asthma or rhinoconjunctivitis. and pulmonary oedema. In addition to the allergen-specific potential for causing respiratory sensitisation.ECOLOGICAL INFORMATION Refer to data for ingredients. Immunologically the low molecular weight substances become complete allergens in the organism either by binding to peptides or proteins (haptens) or after metabolism (prohaptens). Possible neurological symptoms arising from isocyanate exposure include headache. is a disorder that occurs as result of exposure due to high concentrations of irritating substance (often particulate in nature) and is completely reversible after exposure ceases. even sudden loss of consciousness. have also been included in the criteria for diagnosis of RADS. anxiety neurosis. RADS (or asthma) following an irritating inhalation is an infrequent disorder with rates related to the concentration of and duration of exposure to the irritating substance. Industrial bronchitis. A respiratory response may occur following minor skin contact. cell-mediated reactions (T lymphocytes) may be involved. gasping and severe distress.10 mg moderate CARCINOGEN 4. are mostly the result of reactions of the allergen with specific antibodies of the IgE class and belong in their reaction rates to the manifestation of the immediate type. for example. The substance is classified by IARC as Group 3: NOT classifiable as to its carcinogenicity to humans. Onset of symptoms may be immediate or delayed for several hours after exposure. A reversible airflow pattern. Exogenous allergic alveolitis is induced essentially by allergen specific immune-complexes of the IgG type. Gastrointestinal disturbances are characterised by nausea and vomiting. ataxia. The material may produce moderate eye irritation leading to inflammation. The disorder is characterised by dyspnea. Repeated or prolonged exposure to irritants may produce conjunctivitis. Unprotected or sensitised persons should not be allowed to work in situations allowing exposure to this material. Isocyanate-containing vapours/ mists may cause inflammation of eyes and nasal passages.POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. which follows: POLYURETHANE POTTING COMPOUND HARDENER #199-1474: Mobility: Quite mobile would spread readily. the response may be severe enough to produce bronchitis with wheezing. insomnia. on spirometry. with the presence of moderate to severe bronchial hyperreactivity on methacholine challenge testing and the lack of minimal lymphocytic inflammation.13 ppm/30 mins Eye (rabbit): 0. on the other hand. this may occur following a single acute exposure or may develop without warning after a period of tolerance. cough and mucus production. allergic bronchial asthma and atopic eczema (neurodermatitis) which is associated with increased IgE synthesis.TOXICOLOGICAL INFORMATION persistent asthma-like symptoms within minutes to hours of a documented exposure to the irritant. Such allergy is of the delayed type with onset up to four hours following exposure. itching. Sensitised people can react to very low levels of airborne isocyanates.Agents Reviewed by the IARC Monographs Group 3 Section 12 . Factors which increase the sensitivity of the mucosa may play a role in predisposing a person to allergy. during infections or exposure to irritant substances. Evidence of carcinogenicity may be inadequate or limited in animal testing. without eosinophilia... the exposure period and the genetically determined disposition of the exposed person are likely to be decisive. the amount of the allergen. Pulmonary sensitisation may produce asthmatic reactions ranging from minor breathing difficulties to severe allergic attacks. . Inhalation (human) TCLo: 0. 4' Methylenediphenyl diisocyanate International Agency for Research on Cancer (IARC) . Particular attention is drawn to so-called atopic diathesis which is characterised by an increased susceptibility to allergic rhinitis. continued. depression and paranoia. euphoria.0 CD 2009/3 Page 13 of 16 Section 11 .

POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. However. but.Aerobic .High (hours): ■ Half. Degradation of the hydrolysis products will occur at varying rates depending on the moiety formed.Low (hours): ■ First order hydrolysis half..8 0. lakes and rivers) is expected to take years.58 12 ■ Hydrolysis would represents the primary fate mechanism for the majority of the commercial isocyanate monomers.life Surface water .Low (hours): ■ Photooxidation half. 4' diphenylmethane diisocyanate (MDI) Persistence: Water/Soil Persistence: Air No data Bioaccumulation Mobility LOW LOW LOW LOW continued. .High (hours): ■ Half. is tempered somewhat by the lack of water solubility. ■ DO NOT discharge into sewer or waterways. In wastewater treatment this process is not expected to be significant.life Soil .. In the absence of hydrolysis.58 24 6 24 6 672 168 2688 672 5.life Ground water .Anaerobic .Low (hours): ■ Half.High (hours): ■ Half. sorption to solids (e.4'-DIPHENYLMETHANE DIISOCYANATE (MDI): ■ Half. Atmospheric degradation is not expected with removal from air occurring by washout or dry deposition.24-134. Migration to groundwater and surface waters is not expected due to sorption or hydrolysis.Low (hours): ■ Half. Most of the substances take several months to degrade.life air .life (hours): 24 6 5.life Surface water .0 CD 2009/3 Page 14 of 16 Section 12 .life Air .life Air .Low (hours): ■ Aqueous biodegradation .High (hours): ■ Aqueous biodegradation . sludge and sediments) will be the primary mechanism of removal. Biodegradation is minimal for most compounds and volatilisation is negligible. Sorption to solids in wastewater treatment is considered strong to very strong for most compounds. [RS Components] 4.37mg/L Ecotoxicity Ingredient Polyurethane Potting Compound Hardener #1991474 4.8 0. But hydrolysis should be considered one of the two major fate processes for the isocyanates.life Soil .Aerobic . Aerobic and/or anaerobic biodegradation of the isocyanates is not expected to occur at significant levels.life Ground water . Toxicity Fish: LC50(96)95.g.life air .Anaerobic . Sorption to sediments and soils in the ambient environment is very strong in most instances.Low (hours): ■ Half. Aquatic Toxicity: Static Acute (fish) LD50: >100 mg/l Flora and fauna are liable to be adversely affected.High (hours): ■ Photooxidation half.ECOLOGICAL INFORMATION Persistence & Degradability: Reacts readily with atmospheric moisture and is thus readily degraded to harmless poly-urea type products.Low (hours): ■ Aqueous biodegradation . Volatilisation from surface waters (e.g.High (hours): ■ Half. the low to very low solubility of these substances will generally lessen the effectiveness of hydrolysis as a fate pathway.. Review of the estimated properties of the isocyanates suggest that sorption is the primary removal mechanism in the ambient environment and in wastewater treatment in the absence of significant hydrolysis. Hydrolysis of the N=C=O will occur in less than hours in most instances and within minutes for more than 90% of the commercial isocyanates.High (hours): ■ Aqueous biodegradation ..

■ The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. • Bury or incinerate residues at an approved site. "International Air Transport Association (IATA) Dangerous Goods Regulations".DISPOSAL CONSIDERATIONS • DO NOT recycle spilled material."Australia High Volume Industrial Chemical List (HVICL)". 26447. Section 14 . • Consult State Land Waste Management Authority for disposal.26447-40-5) is found on the following regulatory lists.40."Australia Hazardous Substances".8. "Australia .5 ■ Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references.40R43 (MDI) 5 INGREDIENTS WITH MULTIPLE CAS NUMBERS Ingredient Name 4.REGULATORY INFORMATION POISONS SCHEDULE: S6 REGULATIONS Regulations for ingredients 4.Queensland Hazardous Materials and Prescribed Quantities for Major Hazard Facilities"."IMO MARPOL 73/78 (Annex II) .68."Australia Inventory of Chemical Substances (AICS)". • Neutralise spill material carefully and decontaminate empty containers and spill residues with 10% ammonia solution plus detergent or a proprietary decontaminant prior to disposal. IATA."International Agency for Research on Cancer (IARC) ."Australia National Pollutant Inventory"..Agents Reviewed by the IARC Monographs".chemwatch.0 CD 2009/3 Page 15 of 16 Section 13 . Risks may be determined continued.TRANSPORTATION INFORMATION HAZCHEM: None (ADG6) NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS: UN.diphenylmethane diisocyanate (MDI) CAS 101. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. • Puncture containers to prevent re-use. 4' . . • DO NOT seal or stopper drums being decontaminated as CO2 gas is generated and may pressurise containers. A list of reference resources used to assist the committee may be found at: www.diphenylmethane diisocyanate 26447."OECD Representative List of High Production Volume (HPV) Chemicals" No data for Polyurethane Potting Compound Hardener #199-1474 (CW: 4523-71) Section 16 ."GESAMP/EHS Composite List of Hazard Profiles .Hazard evaluation of substances transported by ships". 4' .OTHER INFORMATION Denmark Advisory list for selfclassification of dangerous substances Substance CAS Suggested codes 4.4'-diphenylmethane diisocyanate (MDI) (CAS: 101-68-8.net/references."IMO IBC Code Chapter 17: Summary of minimum requirements".List of Noxious Liquid Substances Carried in Bulk". IMDG Section 15 .POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2..

0 CD 2009/3 Page 16 of 16 Section 16 . as permitted under the Copyright Act. review or criticism.OTHER INFORMATION by reference to Exposures Scenarios. Apart from any fair dealing for the purposes of private study. frequency of use and current or available engineering controls must be considered. .POLYURETHANE POTTING COMPOUND HARDENER #199-1474 Chemwatch Independent Material Safety Data Sheet Issue Date: 19-Feb-2008 NA317TC CHEMWATCH 4523-71 Version No:2. research. TEL (+61 3) 9572 4700. Scale of use. Issue Date: 19-Feb-2008 Print Date: 5-Feb-2010 This is the end of the MSDS. This document is copyright. no part may be reproduced by any process without written permission from CHEMWATCH.