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reference:http://www.guidechem.com/cas-690/69045-84-7.

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Simple method to make 2,3-dichloro-5-(trifluoromethyl)pyridine 2,3-dichloro-5-(trifluoromethyl)pyridine, guidechem, 69045-84-7 IUPAC Name: 2,3-Dichloro-5-(trifluoromethyl)pyridine Empirical Formula: C6H2Cl2F3N Molecular Weight: 215.988 EINECS: 410-340-5 Appearance: Light yellow liquid Density: 1.542 g/cm3 Flash Point: 79.4 C CAS NO: 69045-84-7 Enthalpy of Vaporization: 40.73 kJ/mol Boiling Point: 188.5 C at 760 mmHg Vapour Pressure: 0.825 mmHg at 25C Melting Point: 8-9 C 2 - amino -3 - chloro-5 - (trifluoromethyl) pyridine as the new pesticide intermediates for their preparation, in turn comprising the steps of: the presence of an organic solvent, 2,3 - dichloro-5 (trifluoromethyl) pyridine in 125 -135 , pressure 2.0-3.5MPa of ammonia solution, removing the organic solvent the reaction solution, washed with water, centrifuged, and dried to give the product. The invention process is simple, easy to operate, suitable for industrial production. The resulting high purity, purity 99%, the yield of about 90%, the production cost is low. The present invention is to solve the technical problem of providing 2 - amino -3 - chloro-5 (trifluoromethyl) pyridine method, simple process. Easy to operate, no waste water, waste, high purity and high yield.The present invention is 2 - amino -3 - chloro-5 - (trifluoromethyl) pyridine, characterized by comprising the step steps of: (1) in the presence of an organic solvent, 2,3 - dichloro-5 - (trifluoromethyl) pyridine in the pass liquid ammonia at 125-135 C, under pressure of 2.0-3.5Mpa ammonolysis 8-15 hours to 2 3 dichloro-5 - (trifluoromethyl) pyridine meter, with a molar ratio of ammonia 1:10 ~18; (2) The reaction solution was removed by distillation, the organic solvent, then washed and centrifuged to obtain a product. Said step step l organic solvent can be used methanol, ethanol, isopropanol, ethyl ether. 2, 3 - dichloro-5 - (trifluoromethyl) pyridine and the mass ratio of the organic solvent is l: 2-10. Step (1) The organic solvent may preclude the use of methanol, ethanol, isopropyl alcohol or ethyl ether, 2, 3 - dichloro-5 - (trifluoromethyl) pyridine and the mass ratio of the organic solvent is 1:0.5-10. Advantages of the invention:

Process is simple and easy to operate, suitable for industrial production, no waste water, waste. To obtain a product of high purity, purity> 99%, the yield of about 90%, the production cost is low. Following examples illustrate the invention, but not limit the present invention. Example h (a) ammonia solution To 5 liter autoclave is pumped into 2, 3 - dichloro-5 - (trifluoromethyl) pyridine1000g, methanol, 1500g, ammonia 935g. Open stirring, electric heating jacket open, set the temperature at 135'C, when the kettle temperature reached 135'C, the device automatically stops heating (temperature below 135'C, the device automatically heating), a pressure of 3.5MPa , then for 8 hours to cool down after a start (stop electric heating), the temperature dropped to 4 (TC, has begun to discharge pressure (while playing exhaust absorption system) pressure to 0. 0Mpa, pass gas into the air to catch more than 2 hours to ammonia is not so far. The reaction mixture was pumped into the methanol distillation kettle, methanol was distilled off at atmospheric pressure, when the ammonia solution compound content is less than 10% of methanol, the distillation was stopped, cooled to 4 (TC, large amount of water was added to the kettle and washed with water (while stirring was) put into the centrifuge drying, placed in a drying box, after drying the sample analysis (GC detection) content> 99%, packaging and storage. Want to learn more information about 2, 3 - dichloro-5 - (trifluoromethyl) pyridine, you can access the guidechem.com. Guidechem.com is just a place for you to look for some chemicals.