PATHOPHYSIOLOGY OF DENGUE

Bite of a Virus carrying Aedes mosquito Mosquito injects fluid into victim’s skin Virus enters blood stream Infects cells and generate cellular response Initiates immune response (Stimulates release of cytokines) Cytokines destroys cell membrane and cell wall (Viral antigens found in monocytes) Fluid shift

When treated early with doctor prescribed medications and managed to prevent the appearance of other symptoms IVF’s and Electrolyte replacements and precautions patient recovers

when illness become severe damage cells due to both cytokines and virus fluid shift from ICF-ECF

manifest evanescent rashes

rashes in several areas of the body

bloody vomitus, urine, and stool circulatory collapse shock DEATH

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