George Emil Palade

-biographyBaicoianu Alexandru Clasa a XII-a I

I. Introduction
George Emil Palade was an American doctor and scientist, having Romanian nationality. His main domain of research was cell biology and this is the reason he was awarded, in 1974, the Nobel Prize for Physiology and Medicine. His name is related to the discovery of cellular ribosomes of the endoplasmic reticulum and sometimes they are simply called the particles of Palade. As some notable rewards, he was elected a Member in the US National Academy of Science in 1961. Later, in 1986, he received the U.S. National Medal of Science in Biological Sciences for “pioneering discoveries of a host of fundamental, highly organized structures of living cells”.

II. His life
He was born in 1912 in Iasi, his father was a philosophy professor and his mother was a high school teacher. When he was 7, he started his educational preparation at “Mihail Kogalniceanu” School of Iasi where he spent 3 years. At the entrance of this school, there is a memorial plaque where is mentioned his name and his tribute to the domain of science. George Emil Palade received his M.D. in 1940 from the “Carol Davila” School of Medicine, in Bucharest, Romania. He was a member of the faculty there until 1946, when he went to the United States for postdoctoral studies. There, he joined Prof. Albert Claude at the Rockefeller Institute for Medical Research. In 1946 he married the daughter of the American engineer Nicolae Malaxa, Irina Malaxa. They had 2 children: a daughter, Georgia Palade Van Malaxa and a son, Philip Palade. In 1952, Palade got his naturalization in the United States, becoming a citizen of this country. He worked at

California. as well as a Dean for Scientific Affairs (Emeritus). In 1988 he was also elected an Honorary Member of the American-Romanian Academy of Arts and Sciences (ARA). In the experiment Palade and his colleagues were able to confirm an existing hypothesis that a secretory pathway exists and that the Rough ER and the Golgi apparatus function together.S. he was awarded the “Louisa Gross Horwitz” Prize from Columbia University together with Renato Dulbecco. His Nobel lecture. Presently. Palade used electron microscopy to study the internal organization of such cell structures as ribosomes. the Chair of Cell Biology at Yale is named the "George Palade Professorship". he was awarded in 2007 by the president Traian Basescu the National Order “Steaua Romaniei” (The Romanian Star).D.. At U. Palade was the first Chairman of the Department of Cell Biology at Yale University. he married again. and was a professor at Yale University Medical School (1973–1990). After his first wife’s death. especially in the molecular biology. and others.C. the biology expert Marilyn Gist Farquhar. and University of California. San Diego (1990–2008). was entitled: "Intracellular Aspects of the Process of Protein Secretion". related to his previous research carried out at the Rockefeller Institute for Medical Research. In Romania. published in 1992 by the Nobel Prize Foundation. 1974. In 1970.the Rockefeller Institute (1958–1973). mitochondria. Palade was Professor of Medicine in Residence (Emeritus) in the Department of Cellular & Molecular Medicine. chloroplasts. He was elected an Honorary Member of the Romanian Academy in 1975. co-winner of 1974 Nobel Prize in Physiology or Medicine "for discoveries concerning the functional organization of the cell that were seminal events in the development of modern cell biology". At the Rockefeller Institute for Medical Research. His most important discovery was made while using an experimental strategy known as a pulse-chase analysis. 2 . George Emil Palade died in the United States when he was 96 and left behind some of the most important discoveries in science. delivered on December 12. the Golgi apparatus. in the School of Medicine at La Jolla.

Bibliography  Wikipedia – Romanian Section – George Emil Palade  Wikipedia – English Section – George Emil Palade  Google Images for pictures in the biography 3 .III.

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