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Accurate Imaging of the Brain Functions Non-Invasively

Simultaneous measurement of 306 magnetoencephalography (MEG) and 64 electroencephalography (EEG) channels localizing functional areas most accurately Flexible and highly developed software helps to perform timeefficient data analysis Ultra-low system noise resulting in reliable diagnosis Fully supine and seated positions easy to change, giving optimal patient comfort Low cryogen consumption providing reduced operation costs

Hardware Sensor Array

Field distribution sampled by 510 coils at distinct locations. Coils configured into 306 MEG channels The coil configuration optimally combines the focal sensitivity of 204 planar gradiometers and the widespread sensitivity of 102 magnetometers Accurate geometry and excellent balance of the sensors provided by thin-film technology Interference compensation by on-line Signal Space Projection (SSP) using the sensor array as a reference; involves no increase of white noise Whole-head design with realistic shape based on standard (EN960:1994)

Patient Handling System

Measurement positions: fully supine and seated Mobile patient bed with adjustable upper bed Mobile patient chair. Rigid gantry minimizes vibration artefacts; head is supported by the helmet itself to gain minimal distance between functional brain areas and the sensors Optional pediatric chair-insert

Continuous recording of head position signals Configurable sets of 32 MEG/EEG channels can be monitored continuously

Data Plotting

Display and plotting of evoked-response data or segments of continuous data Multiple data sets can be overlaid and displayed simultaneously. Mathematical operations between data sets supported

Head Phantom

32 current dipoles down to 34 mm from phantom origin and 4 magnetic dipoles

Source Estimation

Both spherically symmetric and boundary element conductor models supported Single moving dipole and time-varying multiple dipole analysis Display and forward modelling of EEG signals in 1- or 3-layer spherically symmetric conductor model Simulation of signals produced by multiple time-varying dipole sources

System Noise

Low noise gradiometers: white noise typically 3 fT/(cmHz) Low noise magnetometers: white noise typically 3 fT/Hz

Data Acquisition

Up to 450 channels can be sampled simultaneously. Distributed, upgradable architecture based on multiple parallel real-time computers Digital signal processors to ensure precise and identical filtering and sampling of all channels Resolution of conversion: 24 bits/sample, samples are stored on disk as 16-bit words Sampling rate for 306 MEG and 64 EEG channels: 5 kHz as standard, 8 kHz as an option Fully integrated EEG system with 60 singleended and 4 differential channels. Additional 64 single-ended channels available as an option Two EEG-caps, adult and child sizes, other sizes available as options DC and AC measurement for both MEG and EEG 16 digital trigger lines, 8 auxiliary analog input channels 12 miscellaneous +/ 10 V analog output channels available as an option

Workstation Configuration

Acquisition workstation (HP Model C3700 or equivalent) and analysis workstation (HP Model B2600 or equivalent). Dual monitor configuration in both workstations 512 Mbyte of RAM, 36 Gbyte hard disk per workstation, and CD-ROM/DVD-ROM drive 9.1 Gbyte magneto-optical disk drive or equivalent. 20-40 Gbyte DDS4 DAT drive (compressing) or equivalent Optional high-reliability RAID-server with DLT backup system including CD-RW unit

Signal Processing

Several abstraction levels including windowing interface, functionality accessible through commands, and full programmability in LISP Extensive set of mathematical functions including FFT, power- and cross-spectrum estimates, template matching, matrix operations, off-line averaging, and slowwave/spike analysis Tools available to build up virtual channels, e.g., for single trial analysis or for virtual depth electrode purposes

Software Data Acquisition

Control and display of both MEG, EEG, and trigger channels on the acquisition workstation Data acquired continuously with external events marked on digital trigger lines Real-time selective averaging with adjustable on-line display. Supports up to 20 response categories Real-time artifact rejection for MEG, EEG, and EOG/EMG/ECG channels

MRI Integration and Report Composer

MRI dipole overlay and fast browsing through the interpolated images with zooming and panning MRI segmentation for 3-D surface rendering and for boundary element conductor models Electronic canvas for transporting graphics and illustrations from other software modules using drag-and-drop technique. Supports several different layouts and commonly used export data formats MRI import/export functions using DICOM 3.0

Cryogenic System

Low boil-off rate in both measurement positions enabling a refill interval of 7 days Safety exhaust line to ensure patient safety

Data subject to change. Some restrictions may apply.

Development, manufacture: Elekta Neuromag Oy FINLAND TEL +358 10 394 4500 FAX +358 10 394 4501

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