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Journal of Indian System of Medicine
Jayanti Veda (Tridax procumbens) Unnoticed Medicinal plant by Ayurveda
SRP Kethamakka , Meena S Deogade
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Head, Panchakarma, email@example.com, Reader, Dravyaguna, MGACH&RC, Wardha, (MS), JISM1403H Received for publication: January 19, 2014;Accepted: February 11, 2014
How to cite the article: SRP Kethamakka, Meena SD, Jayanti veda (Tridax procumbens) - Unnoticed Medicinal plant by Ayurveda, J-ISM, V2 N1, Jan- Mar 2014, pp 6-22
Abstract: Indian Traditional / folklore Medicine is source of many herbs which are not included in Ayurveda material medica. As potential to develop new compounds and chemotherapeutic agents are found through in vitro and vivo studies, it is right time to include new herbs in to Ayurveda pharmacopeias. Tridax is one such multifaceted weed available throughout the continent which can be used as a substitute for many herbs. The prime focus of scientific Ayurveda is to strengthen the herbal treasure house through Ayurvedic concept based researches. The present endeavor embarks on analyzing the updated information of Tridax identification, phyto-anatomy, phyto-chemical study, toxicity and therapeutics, to fortify the knowledge of rich traditional folkore practices followed since years to the well being of mankind. Key words: Tridax, Jayantiveda, Kshudra-Shevantika, Kotobukigiku, Coat Buttons Plant
Traditional Indian Medicine (TIM) is an important source of potentially useful new compounds for the development of chemotherapeutic agents. Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs have been isolated from natural resources . It has been estimated that herbal medicines serve about 80% of the world's population health need for millions of people in the rural areas of developing countries and more than 65% of the global population use traditional medicine for basic health care . WHO estimated that approximately one fourth of the 500 million prescriptions written in US each year contain a mention of leafy plant extracts or active ingredients obtained from or modeled on plant substances . According to one estimate 20,000 to 35,000 species of plants are used as medicines, pharmaceuticals, cosmetics and neutraceuticals by different ethnic groups the entire world over .
It is necessary to convert ethno-medicine practices into organized system either following through scientific extractive evaluations and /or on Ayurveda systemic approaches. In recent, herbal medicines and extracts have gained renewed interest for several reasons; affordability, low pricing, no side effects, solutions for chronic diseases and disorders, time tested remedies (folklore), preventive approaches, etc. . The present review is aimed to notice biological and medicinal activity of Tridax and introducing such unnoticed herbs for inclusion in Ayurveda Materia-medica which helps in serving the ailing mankind. Distribution: Tridax procumbens L. is a common medicinal herb called Jayanti Veda in Sanskrit  belonging to family Asteraceae. It is best known as a widespread weed coat buttons plant, wild daisy and pest plant and Kotobukigiku in Japanese . The
Journal of Indian System of Medicine Vol.2-Number 1, January-March, 2014
and of oil with AOAC method 999. 30]. perennial . Microscopic study The leaf section shows single layered upper epidermis consisting of polygonal tabular cells about 40-70 μm by 15 to 30 μm with a single layer of cylindrical palisade cells about 18 to 30 μm wide and 60 to 70 μm long.SRP Kethamakka1. alternating in position so that each lies on a different radius. and methylene chloride for phytosterols. persistent.5 – 6 mm in length with inflorescence capitulum. derivatisation of the sterols. opposite. spongy parenchyma 2-4 layered. It has daisy-like yellow centered white or yellow flowers with three toothed ray floret.10 . bristles of disc achenes alternately longer and shorter. Jayanti veda (Tridax procumbens) . up to 60 cm high or about 12-24cm long with few leaves 6-8cm long and very long slender solitary peduncles a foot or more in length.2-Number 1. 19] and it produces a hard achene cypsela  fruit that is covered with stiff hairs . and separation and quantification of the sterol derivatives by gas chromatography (GC) using a capillary column . disk-florets and Basal placentation. 20 ml of vehicle was taken separately to which 2 gram of dried extract was added and sonicated. Simple pitted vessels are present.02 . hairy and arrow shaped . The extraction commonly carried out according to Tram method . unicellular covering trichomes of length 200 μm . sometimes three lobed. The other method is.Unnoticed Medicinal plant by Ayurveda. Preparation of extract dose The powder compound obtained from extract of Tridax leaves was administered orally at different doses by dissolving it in Normal saline [29. with week straggling.pp-6-22 plant is native of tropical America and naturalized in tropical Africa. 2% acacia suspension was prepared by suspending 2 gram of accurately weighed Tridax powder in 100 ml of 0. clean-up of the extract. dried leaves powder.2. Extraction Procedure: Various methods are followed to draw the extracts of Tridax using a soxhlet extractor from Juice of fresh leaves. and collenchyma cells of 70-115 μm diameter.5 . exstipulate. It is widely distributed throughout Indo-Pak region [11. It's Leaf is simple. cells polyhedral or isodiametric in shape.9% saline. Maharashtra. glandular trichomes of stem are present. root cortex cells of diameter 80-120 μm are present. acute with two types of flowers such as ray-florets. latex cells are seen in the stem. and these flowers are small. Endodermis is indistinct. air dried whole plant is pulverized and extracts are prepared for 72 hours and the yield found to be 6% W/V at room temperature [25-32]. Australia and India . followed by alkaline hydrolysis (saponification) extraction of the non-saponifiables. The stele is surrounded by a single layer of pericycle and has xylem and phloem arranged in a circle.5 – 1 mm in diameter and densely ascending pubescent. ovate-lanceolate 2 to7 cm and lamina pinnatisect. The root section shows composed of thin walled tangentially elongated cells. Its widespread distribution and importance as a weed are due to its spreading stems and abundant seed production . Madhya Pradesh and Chhattisgarh ) and is employed as indigenous folklore medicine for variety of ailments. Powder microscopy of the plant showed fibers of 175 μm length. Meena SD. [18. procumbent herb with woody base sometime rooting at the node. The leaves are short. achenes 1. this Journal of Indian System of Medicine Vol. long peduncled heads. January-March. Asia. Description: Tridax is a hardy. The stem section shows cortex consisting of 1-2 layers of collenchyma and 6-7 layers of parenchyma. spiral vessels are present in the leaf. The linearity of the dependence of response on concentration was verified by regression analysis . hispid. 3. 12].5 mm long x 0. Standard solutions were prepared in methanol for alkaloids and tannins. 2014 7 . Cortex composed of oval to polygonal parenchymatous cell. Tridax is present throughout India (Andhra Pradesh. and the analysis of sterols was carried out according to AOAC method 994. This involved extraction of the lipid fraction from homogenized sample material.
etc . linoeic. quercetin (21. characterized as b-sitosterol 3-O-bD-xylopyranoside. Flower extract has even b-Sitosterol-3-O-b-Dxylopyranoside . campasterol. which has been isolated from the flowers of Tridax . betaamyrin . 12hydroxytetracosa-15-one. Oleanolic acid was obtained in good amounts and found to be a potential anti-diabetic agent when tested against aglucosidase . β-amyron. 40].2-Number 1. The flower yields steroidal saponin. Compared to test control.67%). aspartate transaminase (37.74-64. myristic. linolenic. behenic. βamyrone. beta-sitosterol. 1-(2. Jayanti veda (Tridax procumbens) . Some of the reported chemical constituents present in the aerial parts of the plant are phytosterols. dimethyl-3hydroxypropyl) isobutyl phthalate.82%). stigmasterol. β-amyrin. traditional 8 Journal of Indian System of Medicine Vol. flsitosterol and tannin has also been reported in the plant . lauric acid. sterols. 3- methyl-non adecylben-zene. robinetin (3. Leaf of Tridax mainly contains crude proteins of 26%.38%). campesterol  and a characteristic triterpene. palmatic acid. 17% of crude fiber. fucosterol. soluble carbohydrates 39%.07%). 2014 . The amount of total phenolics was expressed as gallic acid equivalent (GAE) in milligram per gram dry plant extract using the expression. glucoluteolin. 44]. diadzein (2. In acute toxicity studies with a dose of 250 mg/kg of dried extract on mice were observed for motor reflexes for 48 h. naringenin (4. heptacosanyl cyclohexane carboxylate. Research is being spotlighted on plants and their phytochemicals  and 74% of the plant. Tridax isolations are observed with methyl 14 oxoacagaecunoate. In chronic toxicity studies in two groups extract of Tridax at 250 mg/kg was administered daily for a period of 15 days. stigma sterol. and nobiletin (2. Whereas the fumaric acid. flavones and glycosides [43.2. and the study carried out for a period of 15 days.20%). Tridax have a high phenolic content of 12 mg/g GAE (gallic acid equivalent) . methyl 14-oxononacosanoate.96-57.o.05) alkaline phosphatase (54. flavonoids. consisting mainly of apigenin (29. fucosterol and sitosterol. lauric. in both the species . kaempferol (11. arachidic. Both Tridax procumbens ethanolic extract (TPEE) and Tridax procumbens ethyl acetate extract (TPEAE) suspension were prepared in such manner . Folk & Pharmacology Practices The Ethno pharmacological and traditional use of plants often results in the discovery of new biologically active molecules . lupeol. palmitic and stearic acids ]53]. and 800 mg/kg i. Luteolin. Toxicity Studies The “Staire case” method LD 50 was determined in rats and mice by oral and intraperitoneal route.57%). besides arachidic acid.pp-6-22 produce suspension of 100 mg/ml strength. The plant yielded interesting compounds like luteolin. the treatment dose dependently significantly lowered (P<0. C = c x V/m  The proximate profile shows that the plant is rich in sodium. potassium and calcium .21%). Hence. and alanine transaminase (32.82%) activities .00%).SRP Kethamakka1.91-100.28%). Meena SD. 32-methyl-30ozotetraatriacont-31-en-1-ol along with β-amyrin. No mortality was observed and the behavioral pattern was unaffected .79%). cultural and sometimes ancient uses . Plants have a long history of use in the treatment of many diseases like cancer.derived medicines have a modern indication that correlates with their traditional.Unnoticed Medicinal plant by Ayurveda.13%). biochanin (3. The presence of flavonoid quercitin is confirmed in the plant since the HPLC and HPTLC studies of the ethanolic extract of the whole plant and that of standard quercitin match each other . and calcium oxide 5%.52%). and bergenin derivatives from Tridax [39. quercetin and isoquercetin have been reported from its flowers.p. (-)epicatechin (6. January-March. and polysaccharide. (+)catechin (3. tria contanol. The initial dosing of Tridax was 2000 mg/kg p. Phytochemistry: The Phyoto-chemical investigation reports the isolation of lipid constituents. Twenty-three known flavonoids were detected.
It is used as an ornamental or fodder plant. Hence Tridax recommended for bio-remediation . It is also used as bio-adsorbent for chromium (VI) is one of the highly toxic ions released into the environment through leather processing and chrome plating industries . The studies of Ikewuchi on the elemental composition . diarrhoea and in the West Africa and for a remedy against conjunctivitis [127. It is parasite  killer and also works as insect repellent .171] hypotensive effect [83. Anti-oxidant [78. Immunomodulatory [75. asthma. Its leaves are also used for bronchial catarrh. epilepsy. epilepsy and diarrhea . Anti-hyperglycemic  Anti-diabetic activity [81. Traditionally. stomach ache. Anti fungal . anti-inflammatory [71-74]. None of the tested extracts was active against the yeasts. falciparum parasites with aqueous and ethanolic extracts.Unnoticed Medicinal plant by Ayurveda. Tridax successfully inhibited the growth of Escherichia coli. The Tridax exhibits antimicrobial activity against both gram-positive and gram-negative bacteria  and also found as Antileishmanial .82. Ravikumar on liver antioxidant defense system during lipopolysaccharide-induced hepatitis . and its leaves are cooked as vegetables [23. This plant was also used as a good bioadsorbent for the removal of highly toxic ions of Cr (VI) from industrial wastewater. 123]. Klebsiella pneumonia Proteus vulgaris . liver problems.SRP Kethamakka1. 124. Meena SD.79]. Tridax is traditionally used in the treatment of fever. In another study with essential oils of steam distillation from leaves found for its topical repellency effects against malarial parasite Anopheles stephensi in mosquito cages [122. January-March. This plant was also used for bronchial catarrh. In village side it is a best medicine to stop hemorrhage from cuts and bruises as anticoagulant . Salahdeen on high blood pressure and heart rate on rats . A whole aerial part was active against Mycobacterium smegmatis. In the West Africa sub-region and tropical zone of the world. Tridax is used for the treatment of bronchial catarrh.Wound healing . Hepatoprotective [85-87]. 66. Analgesic . dysentery. Traditional medical practitioners and the native peoples of these areas use the leaves of the Tridax as a remedy against conjunctivitis . malaria. Its action is found as Anti-arthritic . 125] noticed in 1991 . Candida tropicalis and Rhodotorula rubra. Tridax have antiplasmodial activity against chloroquine-resistant P. 68]. cough.2-Number 1. 128. Antimicrobial  also. diabetes.76. 84]. weight reducing activity . antibacterial action . 113] is remarkable. The RBC protection started at a concentration of 100μg/ml . or the fungi: Aspergillus flavus. hemorrhage. Tr i d a x [ 6 9 ] p o s s e s s e s s i g n i f i c a n t pharmacological practices like .pp-6-22 medicine is an important source for the development of novel chemotherapeutic agents which are less toxic and more economic . parasiticidal properties and has marked depressant action on respiration [114. typhoid fever. Jayanti veda (Tridax procumbens) . 67. Journal of Indian System of Medicine Vol. The researches on its efficacy over liver injury  and Lung metastasis  are noticeable. diarrhoea. etc. Anti hepatotoxic . It possesses antiseptic. Aspergillus niger. high blood pressure. and the protective effects of aqueous extract of the leaves against cholesterol and salt loading (in Wistar albino rats) [112. Mucor sp. 24]. diarrhoea and also used as preventive measure for hair falling / promoting hair growth [102. 65. dysentery. and as a hair tonic [64. In Nigeria . 77]. Salmonella group C and Salmonella paratyphi. The cardiovascular effects of aqueous leaf extract (on Sprague-Dawley rat) decreases the mean arterial blood pressure and the higher dose leads to significant reduction in heart rate where as lower dose did not cause any changes in the same . insecticidal. and Trichophyton rubrum . 129]. and analgesic activity . Bacillus subtilis and Staphylococcus aureus . Escherichia coli. The n-hexane extract of the flowers showed activity against Escherichia coli. 2014 9 . Candida albicans.
and β-pinenes were strongly reported for its cytotoxic activity on several cell lines like breast cancer and leukemic cell lines and anti Prostate Cancer activities .10 injected mice makes them potentially valuable drug for cancer treatment . 119]. continues to be a burning global issue due to the indiscriminate and irrational use of antibiotics . Excellent antifungal potential was recorded for free flavonoid of stem (IZ 12 mm. The development and spread of multi drug resistant super bugs especially in the hospital environment.02. Study indicated that Tridax can be used as a source of formulations of antifungal drug for treatment of diseases caused by A. The traditional medicinal plants are emerging as potential sources of new antimicrobial agents  and several workers have reported antibacterial activities of local plants [136. 137.2 mm. E.625 mg/ml) and flower (IZ 10. as well as for fungus Aspergillus niger and Candida albicans [141-147] · Antioxidant Antioxidants prevent the damage done to · 10 Journal of Indian System of Medicine Vol. As the essential oil of Tridax has revealed to have α-pinene. the vast majority have not been adequately evaluated . with same MIC and MFC 0.2. Anti-Cancer Some specific studies have shown that the βpinene. niger.2-Number 1.Unnoticed Medicinal plant by Ayurveda.312 mg/ml) against A. Aqueous extract of the leaves of Tridax is an effective agent in the treatment and prevention of carbon tetrachloride-induced hepatic cytotoxicity. with same MIC and MFC 0. niger . Klebsiella pneumoniae. 138].SRP Kethamakka1. The data suggest that the daily oral consumption of the extract was prophylactic to carbon tetrachloride poisoning. · Anti-fungal Human mycoses. The essential oil of Tridax was found to have 14 compounds and out of which four compounds namely α-pinene (C10H16) β-pinene (C10H16) phellandrene (C10H16) and Sabinene (C10H16) were found to be the major compounds used for cancer treatment . The essential oil of Tridax showed a high cytotoxicity of cancer cell death within 24 hrs for 50 μg which shows the potency of essential oil on killing B16F-10 cells in vitro. Meena SD. 117] along with nutrient/ nutraceutical potential of the leaves [118. and have taken 50 μg as the minimal dose for the anti-cancer studies. especially in immuno· compromised patients are not always successfully treated due to the ineffectiveness or toxicity of the available antifungal drugs. Minimum inhibitory concentrations (MIC). Jayanti veda (Tridax procumbens) . bound flavonoid of stem (IZ 10 mm. The antimicrobial potential of this herb is tested with methanolic extract was found to be more effective than water extract against all bacteria. minimum fungicidal concentrations (MFC) and total activity were evaluated for determination of antifungal potential of each active extract. MIC 0. AI 1.156 mg/ml). 116. coli. Various studies on the anti-bacterial activity of Tridax revealed that the plant extract was effective on Pseudomonas. AI 1.pp-6-22 115. Staphylococcus aureus. 2014 . β-pinene l-phellandrene and Sabinene as their major bioactive compounds as identified and studies reveled that its preventive/ chemotherapeutic effect on experimentally induced lung cancer development. January-March. Anti-bacterial Plants with antimicrobial potential has become the need of today's research  and hundreds of plant species have been tested for antimicrobial properties. It can be concluded that the synergistic effects of essential oil of Tridax on chemoprevention of lung cancer development in B16F. This confirms the use of Tridax in traditional health care for the treatment of liver problems  also. Proteus vulgaris.312 and MFC 0. Author suggests that β-amyrin found in the leaves of this plant could be responsible for its antimicrobial activity . AI 1. From the in vivo drug toxicity study it is clear that the Tridax even in its highest dosage did not show any lethal effect/ abnormality on C57BL/6 mice. The α. along with α-pinene and other terpenes are cytotoxic on cancer cells .
81%) used as standards . but there is disagreement about the steroidal activity . Kg/10mL on Rats as dose volume for Biphasic pain exhibits 95±09 % of reversal. Numerous reports indicate variations in the levels of antioxidants in the diabetic patients [149.pp-6-22 cells by free radicals-molecules that are released during the normal metabolic process of oxidation. 158] inhibit the accumulation of exudate and leucocyte migration between 3 to 6 hrs after carrageenin . The model of leucocyte migration has been used as this is an essential step in the development of inflammation .SRP Kethamakka1.) which generates metabolic products that attack lipids in cell membranes or DNA and associated with several types of biological damage . Formalin induced persistent pain (Biphasic pain). The higher doses have been used as lower doses do not affect leucocyte migration. Acetic acid induced writhing test (Peripheral pain) and CFA induced hyper analgesia in rat (Inflammatory pain) were tested with Tridax procumbens against standard (Diclofenac Sodium). 60 and 120 min.92%) and ascorbic acids (94. 96. 150]. Studies around the world have identified many new plant constituents with antioxidant activity. As this anti nociceptive property of the extract may be attributed to the presence of flavonoids and phytosterol which are present in the plant However. The study of plants that have been traditionally used as pain killers should still be seen as a fruitful and logical research strategy. Anti-inflammatory (exudates) The clinically useful drugs against pain and inflammation exhibit many adverse effects. Oral administration of extract of Tridax procumbens significantly reduced mechanical hyper analgesia in CFA injected rats. A study is expressive that Tridax does not cause ulcer indicating less involvement of prostaglandins in anti-inflammatory effect . The results of the DPPH radical scavenging activity of Tridax against test sample and standard (gallic and ascorbic acids (Fluka)) shows that Tridax possesses very high percentage antioxidant activity. The anti-inflammatory action of Tridax may possibly be due to corticotrophic · influence as evident from increase in weight. 155]. This adrenal corticotrophic effect might be indirectly inhibiting the inflammation by secretion of endogenous cortical hormones.70% at a concentration of 250µg/ml. Jayanti veda (Tridax procumbens) . this leads to considerable interest in search of safer drug for these conditions . reactive hydroxyl radicals (OH. in the search for new analgesic drugs [154. A study reveals that none of the drugs tested potentiated either exudates volume or leucocyte migration. January-March.2-Number 1. The leucocyte migration and exudate studies done at the end of six hours [157. It has been reported that prostaglandins are involved in causing gastric ulcers. The results of Tridax are comparable to NSAIAS in all respects. the superoxide anion radical (O2. The % reversal =100 – (AVG response of test drug/ AVG response of vehicle*100). Tridax-400mpk in Normal Saline vehicle. The measurement of mechanical hyperalgesia was done at 30. among these are the polyphenols . The same quantification of Tridax extract relives peripheral pain 78±07 % Reversal and inflammatory pain with 27±8 % Reversal. Meena SD.89 nm.70 which was observed to be higher than those of gallic (92.Unnoticed Medicinal plant by Ayurveda. with high AA% of 96. leucocyte migration. Tridax extracts may have hydrogen donors thus scavenging the free radical DPPH. Tridax plants are rich sources of natural antioxidant. Tridax has shown significant anti-inflammatory action influencing exudates.70% at 250µg/ml which was observed to be higher than even those of the standards (ascorbic and gallic acids) at a concentration of 250 μg/ml used . Journal of Indian System of Medicine Vol.).). T. 2014 11 . Some of these free radicals include reactive oxygen free radicals species (ROS). hydrogen peroxides (H2O2) and peroxyl (ROO. rat paw edema and granuloma. It shows a reductive potential of 0. procumbens has a percentage antioxidant activity (AA %) of 96. It is suggested that leucocyte migration will detect weaker anti-inflammatory activity and recommend as a good model for rapid screening .
2014 . Cyclophosphamide). Jayanti veda (Tridax procumbens) . and breaking strength were all increased in drug-treated animals as compared to controls. Tridax on developing granulation tissue in rats were studied at 4 day intervals up to 32 days of wounding. A fall in the lysyl oxidase activity was observed in drug-treated animals after day 8. Diabetes is 5th in top 10. January-March. Tridax ethanolic extract showed better results than ethyl acetate extract at 300mg/kg comparatively.pp-6-22 the isolated flavanoid such as procumbentin and quercetin and sterols such as β sitosterol may show more pronounced analgesic activity compared to the extract.2-Number 1. 175] induced Experimental studies revels that the aqueous and alcoholic extracts from Tridax leaves (200 mg/kg) orally administered for 7 days produced a significant decrease in the blood glucose level. protein content. and capillary function  in diabetics. Tridax can impart not only by hypoglycemic effects but also by improving lipid metabolism. The effect of various extracts (whole plant extract.05) comparing with various groups by One way ANOVA followed by Tukey's multiple comparison test. The ethanolic whole plant extract of Tridax exerts an anti-arthritic activity by significantly · · altering the pathogenesis during FCA -induced arthritis in female SD rats without exerting any side effects . antioxidant status. Wound healing The effects of an indigenous drug. · Anti-diabetic Diabetes mellitus occurs throughout the world. The Rheumatoid factor was found negative in animals of all groups of Rat adjuvant polyarthritis. as seen from the significant reduction in the total WBC count . probably as a result of increase in glycosamino glycan content . Anti-arthritic Tridax at 250 and 500 mg/kg has displayed significant anti-arthritic activity comparable with that of indomethacin. The practical usage of juices of various plants achieved the lowering of blood glucose by 10-20% . The authors have reported that whole plant extract has the greatest pro-healing activity with increase in tensile strength and lysyl oxidase activity among the various extracts in both normal and immuno-compromised (steroid treated) rats in dead space wound model. The drug may be having a dual role: one a stimulatory (direct) effect in the initial phase of wound healing and the other a depressant (indirect) effect in the later stage . Kshudra-shevantika (Tridax) in human show not much significant ulcer healing against standard drug Jatyadi taila .Unnoticed Medicinal plant by Ayurveda. Lysyl oxidase activity. Tridax antagonized antiepithelization and tensile strength depressing effect of dexamethasone (a known healing suppressant agent) without affecting anti-contraction and antigranulation action of dexamethasone . particularly in the formalin – induced pain model. butanol extract and ether fraction) of this plant has been studied in dead space wound model . acetic acid induced writhing and in the inflammatory pain model . as Tridax ethanolic extract showed significant (P<0.SRP Kethamakka1. 12 Journal of Indian System of Medicine Vol. protein and nucleic acid content in the granulation tissue. aqueous extract. The profile of malondialdehyde and antioxidant vitamins in the test rats clearly indicate cardio-protective potential and protects against oxidative stress in ocular tissues and support its use in traditional health care practices for the management of diabetes mellitus .05) whereas Tridax ethyl acetate extract was less significant (P<0. Alloxan [174. The plant increased not only lysyl oxidase but also.001– 0. Petroleum extract exhibits very weak anti-diabetic activity . specific activity. Meena SD. Earlier findings suggest that absorption of 14Cglucose and 14C-leucine in rat's intestine was reduced in the case of inflamed rats . of the most significant diseases in the developed world and is still gaining significance . The migration of leucocytes into the inflamed area is significantly suppressed by Tridax ethanolic extract when compared to standard drug (Diclofenac sodium.
2011. The Tridax.  Ikewuchi Jude C.. Chemical Constituents And Micro Propagation Of Three Potential Medicinal Plants. 2014 . 2005. Int J Green Pharm 2008.  Chitra Pai1. March 2010. Rahul SA. Dzikwi. (adulteration) which is well known Ayurvedic medicine for liver disorders [15. A. pp. 72:313-315. Manjusha Borde. Int. which is wildly used in folklore medicine. Β-Sitosterol-3-O-β-Dxylopyranoside from the fl owers of Tridax procumbens Linn. Ayurveda principles are hard nut to crack and a simple chemical evaluation is the better way to adopt. J.al. Mrudula1 and Yashwant Deshmukh. D. has established its therapeutic uses with innumerable studies of in vitro and vivo which recommends itself to be placed in Ayurveda Dravyaguna and Pharmacy. JanMar 2012. Musa and N. it could not make its place in either Ayurveda or Alkaloid therapeutics.  C. References :  Ankita Jain et. Meena SD. I. Bello. P. PC. Ayurveda herbal treasure house is to be expanded with new herbal species identified from folk practice as there is restrictions or extinction of known herbs. Geneva. Medicinal and Economic Plants of Nupe Land. World Health Organization. Int. 123-126. 4(3). 1. of Life Science & 13 Journal of Indian System of Medicine Vol.pp-6-22 Discussion: Tridax procumbens leaves have been traditionally and now experimentally used worldwide for its versatile therapeutic properties. J Chem Sci. Vol 2/Issue 3/Jul-Sept 2012. et. Antidiabetic activity of leaf extract of Tridax procumbense. Ujjwala Kulkarni. 117:263–266.P. It is because of the scarcity of Bhringaraj or not imparted importance to Tridax.): A Weed With Immense Medicinal Importance: A Review. Sowmya Murali.  C. pp.  J. International Journal of Pharma & Bio Sciences. 1(4): 164-173. It is found that Tridax is dispensed as “Bhringraj”. Muhammad G (2003). Chemical Constituents And Micro Propagation Of Three Potential Medicinal Plants. J. J. January-March. Total phenolics and antioxidant activity of Tridax procumbens Linn. Abubakar. African Journal of Pharmacy and Pharmacology Vol. Vol 2/Issue 3/Jul-Sept 2012.  Mann A. Malik. Igboh Ngozi M. Juber Evans Books and Publication pp.Unnoticed Medicinal plant by Ayurveda. However. Herbal medicine: traditional practices (Ed). of Life Science & Pharma Resaecrh. Tridax Procumbens (L. 16]. Abdulkadir NU. Aavishkar Publishers. Malik.SRP Kethamakka1. A. ]8:548-550. At the backdrop of increasing importance of herbal alkaloid usage in medical practice it is necessary to identify the active alkaloids of folk use plants for its therapeutic values. following the extracting methods of alkaloid and testing on animals. pp 322. H. Phytochemical communication a new flavonoid from the aerial parts of Tridax procumbens.  Saxena VK. (2001). Habila1. Conclusion: For many. which are against to the holistic approach is being practiced at present. pp L57-76.P.  Ali M.  General Guidelines for Methodologies on Research and Evaluation of Traditional Medicine. Thus. Jayanti veda (Tridax procumbens) . Int. Ikewuchi Catherine C. 3 Issue 1. Switzerland 2001.al. 2:126-128. Fitoterapia. Jaipur. being time tested and passed through various in vivo and vitro studies. A. Chemical Constituents And Micro Propagation Of Three Potential Medicinal Plants.  C. Antibacterial Activity of Tridax procumbens with Special Reference to Nosocomial Pathogens. Pakistan J Nutrition 2009. Medicinal Uses. Malik. Chemical Profile of Tridax procumbense Linn. a weed spread all over. 78.  Trivedi.P.  Durgacharan AB. Vol. Albert S.544. Medicinal Uses.2-Number 1. of Life Science & Pharma Resaecrh. Suresh GK. Tridax. Medicinal Uses. pp L58. It is far for the understanding of the common Ayurveda practitioners' wisdom to include the local weeds in to daily practice and the planners are under the crutches of hypocrisy. 2006. British Journal of Pharmaceutical Research. future researches based on Ayurveda concept are to be initiated to potentiate the Jayanti Veda.
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