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Each of the following samples may be used in hematology

except:
a. serum from a clot tube
b. EDTA whole blood
c. Sodium citrate whole blood
d. Heparinized capillary blood
a. serum from a clot tube

A 1:200 dilution of a patient's sample was made and 336 red
cells were counted in an area of 0.2 mm2. What is the RBC
count?
a. 1.68 x 1012/L
b. 3.36 x 1012/L
c. 4.47 x 1012/L
d. 6.16 x 1012/L
b. 3.36 x 1012/L

Which one of the following conditions will most likely lead to
hypoxia?
a. methemoglobinemia
b. bacteremia
c. acidosis
d. high levels of 2,3-BPG
a. methemoglobinemia

Which of the following cells are normally present in a normal
blood specimen?
a) RBC, PLT, lymphs, neutrophils, blasts and monocytes
b) RBC, PLT, lymphs, neutrophils, monocytes, eos, basos, a
few bands and a few polychromatopilic RBC
c) RBC, PLT, megakaryocytes, promyelocytes, reactive
lymphocytes, toxic bands and PMN
d) RBC, NRBC, blasts, monos, eos, basos and PMNs
b) RBC, PLT, lymphs, neutrophils, monocytes, eos, basos, a few
bands and a few polychromatopilic RBC

Reticulocytes are the same as polychromatophilic erythrocytes
(RBC exhibiting polychromasia). True or False?
True

ALL morphological characteristics studied in this lesson can
be identified in Wright's stained blood smears. True or False?
False- Pappenheimer bodies need Prussian stain
reticulocytes need vital stain (new methylene blue)

What is the M:E ratio found in a normal bone marrow?
a) approximatelly 3:1
b) approximatelly 1:3
c) 1:1
d) 2:3
a) approximatelly 3:1

1. Which of the following red cell indices reflects the amount
of hemoglobin per individual red cell?

a) Hgb
b) MCV
c) MCHC
d) MCH
d) MCH

2. A blood sample that has moderate anisocytosis with
moderate macrocytes is expected to have?

a) a MCHC greater than 37%
b) a MCV greater than 100 fL
c) a MCH greater than 32 pg
d) normal red cell indices
b) a MCV greater than 100 fL

Which of the following morphological classifications best
describes the hemolytic anemias:

a. microcytic, hypochromic
b. normocytic, hypochromic
c. normocytic, normochromic
d. macrocytic, normochromic
e. macrocytic, hypochromic
c. normocytic, normochromic

An osmotic fragility test shows initial hemolysis of the red
cells at 0.70 % NaCl. This is most consistent with:

a. Hereditary spherocytosis
b. Hereditary ovalocytosis
c. G6PD deficiency
d. Paroxysmal Cold Hemoglobinuria
a. Hereditary spherocytosis

One of the following best indicates intravascular hemolysis

a. increased serum bilirubin
b. increased urine bilirubin
c. increased reticulocytes
d. hemoglobinuria
d. hemoglobinuria

1. One of the following may lead to pernicious anemia:
a. Gastric resection
b. Strict vegan diet
c. Diphyllobothrium latum infection
d. Pregnancy
a. Gastric resection
PA is due to lack of intrinsic factor which is made by gastric
mucosa (parietal cells)

2. The aplastic anemias may be classified by which
morphological group?
a. Normocytic/Normochromic
b. Macrocytic/Normochromic
c. Megaloblastic/Normochromic
d. Microcytic/Hypochromic
a. Normocytic/Normochromic
like hemolytic

3. One of the following statements regarding IDA is NOT true:
a. Serum iron and ferritin levels are low, TIBC is high
b. Reticulocyte counts will be low
c. RDW will be high
d. Microcytic & hypochromic cells will be observed with
relatively little deficiency
d. Microcytic & hypochromic cells will be observed with
relatively little deficiency

Which if the following hemoglobins rank second in variant
hemoglobins worldwide?
a) Hgb S
b) Hgb E
c) Hgb H
d) Hgb C
d) Hgb C

Which hemoglobin will show crystals appearing like bars of
gold in the peripheral smear?
a) Hemoglobin CC disease
b) Hemoglobin DD disease
c) hemoglobin EE disease
d) hemoglobin SS disease
a) Hemoglobin CC disease

Of the four clinical states of alpha thalassemia, which is
incompatible with life?
a) alpha thalassemia silent carrier
b) alpha thalassemia trait
c) hemoglobin H disease
d) Hydrops Barts fetalis
b) alpha thalassemia trait

What is the majority hemoglobin in thalassemia major?
a) Hemoglobin A
b) hemoglobin A2
c) hemoglobin F
d) hemoglobin H
c) hemoglobin F

How many blast cells in the bone marrow aspirate smear are
necessary for a diagnosis of acute leukemia using the WHO
criteria?

a) 20%
b) 10%
c) 30%
d) none of the above
c) 20%

Which cytochemical reactions would you expect from an Acute
Myelomonocytic Leukemia?

a) MPO positive SBB negative
b) MPO, SBB, NASDA, ANAE positive, PAS negative
c) MPO, SBB positive, NASDA and ANBE negative
d) MPO, NASDA and PAS negative
b) MPO, SBB, NASDA, ANAE positive, PAS negative
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