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1 Drugs in Medicine
Cardiology
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Indications Drug Dose Every For Admin Note
Heart failure
Diuretics Frusemide (lasix) 40-160 mg Oral, IV, IM
Acute pulmonary edema
Frusemide (lasix) 40 mg IV To be repeated according to response
Rheumatic fever
Secondary prophylaxis Benzathine penicillin 1.2 million U / month IM Till 25 yr, or 5 yr from last attack or for life
Erythromycin 250 mg /12 h In penicillin allergic patient
Eradication of streptococcal infection Benzathine penicillin 1.2 million U / week 3 weeks IM
Erythromycin 250 mg / 6h 10 days In penicillin allergic patient
Anti-inflammatory Aspirin 50 mg/kg / day 6 weeks Orally Divided on 6 doses
Prednisone 1 mg/kg / day 4 weeks Orally Withdrawn gradually on 4 weeks
Infective endocarditis
Prophylactic treatment
For dental procedure
Amoxicillin
3 gm 1 hour Before procedure Orally
1.5 gm 6 hour After procedure Orally
Erythromycin 1 gm 1 hour Before procedure Orally In penicillin allergic patient
0.5 gm 6 hour After procedure Orally In penicillin allergic patient
For genitor-urinary & GIT procedure Amoxicillin 1gm 1 hour before, 2 hours
after procedure
IV or IM

Gentamycin 120 mg
For cardiac surgery & catheterization Cefotaxime 2 gm 2 hours before procedure
1 gm / 6h 4 doses after procedure
Curative Soluble penicillin 6 million U / 6h For at least 6
weeks
IV
Gentamycin 80 mg / 8h IV
Myocardial infarction
Relief of pain Morphine 5-10 mg IV
Treatment of dysrrhythmias Lidocaine 50-100 mg IV For ventricular fibrillation
Atropine 0.5-1 mg IV For marked bradycardia
Relief of emotional stress Diazepam 2-5 mg tds
Thrombolytic therapy Streptokinase 1.5 million U / 100 ml saline IV infusion in 1 hour
Antiplatelet Aspirin 75-300 mg / day
Anticoagulant Heparin 5000 U Till discharge SC
Pulmonary embolism
Prophylaxis Heparin 5000 U / 12h SC For predisposed patient
Curative
Analgesics Pethidine 50 mg IV
Anticoagulant Heparin 5000 U / 6h 4 days SC Then heparin & oral anticoagulant for another 4 days
Thrombolytic therapy Streptokinase 1.5 million U / 100 ml saline IV infusion in 1 hour
Hypertension
Hypertensive emergency Diazoxide 300 mg Rapidly IV
Na nitroprusside 100 mg In 1 liter glucose IV
Hydralazine 20 mg IV
Aldomet 250 mg IV
Nifedipine 10 mg Sublingual
Paroxysmal supraventricular tachycardia
During attack in hemodynamically stable
patient
Verapamil 5 mg IV
The same in atrial flutter Propranolol 5 mg IV
Digoxin 1 mg IV
Paroxysmal ventricular tachycardia
During attack in hemodynamically stable
patient
Lidocaine
100 mg IV infusion Then
4 mg / min 4 hours IV
Amiodarone 15 mg/kg IV infusion The same in atrial fibrillation
Premature beats
Propranolol 40-80 mg / day
Verapamil 80-160 mg / day

Hepatology & gastrointestinal diseases
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Indications Drug Dose Every For Admin Note
Treatment of portal hypertension & varices
Primary prophylaxis Propranolol (Inderal) 80-160 mg / day
Management of variceal bleeding Vasopressin (Pitressin) 20 U in 100 ml glucose 5% over 1 min IV Better with nitroglycerin
Telipressin (Glypressin) 2 mg / 6h IV Better with nitroglycerin
Somatostatin (Sandostatin) 50 μg / hour IV infusion
Liver cell failure
Treatment of hepatic encephalopathy Neomycin 1 gm / 6h Orally Not more than 2 weeks
Metronidazole 2 gm / day Orally Instead of neomycin
Ascites
Diuretics Aldactone 100 mg / day Up to 44 mg/ day
Frusemide 40 mg / day Up to 80 mg/ day
Abdominal paracentesis Albumin (salt free) 6 gm / Liter IV For replacement
Amebic liver abscess
Medical treatment Metronidazole (Flagyl) 500 mg tds 1 week
Tinidazole (Fasigin) 2 gm / day 5 days
Malabsorption syndrome
Treatment of tropical sprue Tetracycline 250 mg / 6h Up to 6 months
Combination of both drugs
Folic acid 5 mg / day
Intestinal amebiasis
Luminal amebicidals Furamines (Furamid) 500 mg tds 5 days
Luminal & tissue amebicidals Metronidazole (Flagyl) 500 mg tds 10 days For acute & chronic intestinal & hepatic
amebiasis Tinidazole (Fasigin) 2 gm / day 5 days
Bacillary dysentery
Antimicrobials Ciprofloxacin 500 mg / 12h 5days
Ulcerative colitis
Prednisone 40-50 mg / day In acute attack
Sulphasalazine (Salazopyrine)
1 gm tds In acute attack
1 gm / day As maintenance
5 aminosalicylic acid (Pentasa) 1000 mg / day
Crohn’s disease
Prednisone 30-60 mg / day In acute attack
Metronidazole 800 mg tds For sever perianal disease


 
 
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2 Drugs in Medicine
Respiratory diseases
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Indications Drug Dose Every For Admin Note
Lobar pneumonia
Specific treatment Amoxicillin 500 mg / 8h Orally Usuall treatment
Erythromycin 500 mg / 8h Orally In patient allergic to penicillin
Lung abscess
Antibiotics Amoxicillin 1 gm / 6h
5 days IV Combination Metronidazole or 500 mg / 8h
Clindamycin 300 mg / 8h
Amoxicillin 500 mg / 8h
4 weeks orally Combination Metronidazole or 500 mg / 8h
Clindamycin 300 mg / 8h
Bronchiectasis and Acute bronchitis Amoxicillin 500 mg / 8h
COPD
Treatment of respiratory infections Amoxicillin 500 mg / 8h 7 days
Erythromycin 500 mg / 8h 7 days In patient allergic to penicillin
Cotrimoxazole 2 tablets / 12h 7 days
Trial of bronchodilators & corticosteroids Salbutamol 200 mg / 6h Inhalation
Ipratropium 40 mg / 6h Inhalation
Prednisone 30 mg / day Then gradual tapering
Bronchial asthma
Bronchodilators
Selective ß
2
stimulant Salbutamol 2 puffs 100 μg each tds or as required
Terbutalin 2 puffs 250 μg each tds or as required
Salmeterol 2 puffs 100 μg each / 12h
Anticholinergic bronchodilators Ipratropium bromide 20 μg / 8h Inhalation
Oxitropium bromide 200 μg / 12h Inhalation
Corticosteroids
Inhaled steroids Beclomethazone 100 μg / puff
Budesonide 100 μg / puff
Low dose 800 μg / day 2 puffs / 6h
High dose 1000-2000 μg / day 2-3 puffs / 3-5h
Systemic steroids Prednisone 30 mg / day Till improve
Mast cell stabilizers Disodium Cromoglycate 20 mg capsule / 6h Inhalation By spincap
Nedocromil 2 puffs 2 mg each / 6h
Ketotifen 1 mg / 12h Orally
Treatment of acute severe asthma Nebulized salbutamol 5 mg / 4h Nebulized With high concentration OXYGEN
Nebulized ipratrpium 0.5 mg / 4h Nebulized Ma be added
Hydrocortisone 200 mg / 4h 24 hours IV
Prednisolone 60 mg / day 2 weeks Orally Then gradual tapering
Salbutamol 250 μg Over 10 min IV infusion If no improvement
Interstitial pulmonary fibrosis
In cryptogenic fibrosing alveolitis Prednisone 1 mg/kg / day
Pulmonary tuberculosis
Antituberculous drugs:
Standard regimen:
In 1
st
2 months:
· Isoniazid, Rifampicin, Ethambutol OR
Pyrazinamide
In next 4-7 months:
· Isoniazid & Rifampicin
Isoniazid 5-10 mg/kg / day Orally
Rifampicin 10 mg/kg / day Orally 450-600 mg/day
Ethambutol 25 mg/kg / day Orally
Pyrazinamide 30 mg/kg / day Orally
Streptomycin 15 mg/kg / day IM 1 gm/day
Para-aminosalicylic acid (PAS) 250 mg/kg / day Orally 10-15 gm/day
Ethionamide 15 mg/kg / day Orally
Cycloserine 15 mg/kg / day Orally
Neurology
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Indications Drug Dose Every For Admin Note
Hemiplegia
Specific treatment of thrombotic
hemiplegia
Aspirin 75-300 mg / day Orally
Dipyridamole 75 mg tds Orally
Ticlopedine 250 mg tds Orally
Multiple sclerosis
Treatment of relapses Methyl prednisolone 1 gm / day 7 days IV infusion
Beri Beri Vitamin B1 10 mg tds Orally
Leprosy
Antimicrobial therapy Rifampicin 600 mg / day For 2 days/month
2 years in lepromatous
1 year in tuberculous
Dapson 100 mg / day
Clofazimine 50 mg / day
Myasthenia gravis
Anti-cholinestrase Prostigmine (Neostigmine) 15 mg tds Orally
Pyriodostigmine (Mestinan) 60 mg tds Orally More prolonged effect
Treatment of myasthenic crisis Prostigmine 2 mg IM
Tensilon 10 mg IV
Treatment of cholinergic crisis Atropine 2 mg IM
Parkinsonism
Anticholinergic drugs Artane 2 mg 1
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tds Orally
According to severity of condition
Cogentin 2 mg tds Orally
Parkinol 5 mg tds Orally
Tremaril 5 mg tds Orally
Dopaminergic drugs L-Dopa 0.5 gm / day Orally To be increased by 0.5 gm/3 days, maximum dose 5 gm/day
Sinemet (0.25 gm L-Dopa+25 mg carbidopa) 1 tablet / day Orally To be increased by 0.5 tablets /3 days, till improvement
Bromocriptin (Parlodel) 20 mg / day Given with sinemet
Piribedil (trivastal) 20 mg tds Given with sinemet
Amantadine hydrochloride 100 mg tds
Chorea Reserpine 1 mg tds
Haloperidol 3 mg tds
Status epilepticus Epanutin 15 mg/kg 50 ml/min IV infusion
Valium 5 mg IV Repeat after 5 min if seizure recure
Migraine
In between attack treatment Sibelium 10 mg (2 cap) / day 6 months Orally Before sleep
Sandomigran 1 tablet tds
Deseril 1 mg tds
 
 
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3 Drugs in Medicine
Hematology
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Indications Drug Dose Every For Admin Note
Iron deficiency anemia
Oral iron (iron gluconate or sulphate) 300 mg tds Orally
Megaloblastic anemia
Vitamin B12 replacement Hydroxy or cyanocobalamine 1000 μg / day 3 weeks IM Then once/week till anemia is corrected then once/month for life
Folic acid replacement Folic acid 5 mg / day Orally Same in ttt of H.S.Cytosis, Bthalassemia maj. & sickle c.
Chronic myeloid leukemia
Chemotherapy Busulfan 2-6 mg / day Orally
Hydroxyuria 2-6 mg / day Orally
Chronic lymphatic leukemia
Chemotherapy Chlorambucil 4 mg tds Orally
Prednisone 40 mg / day Orally
Acute leukemia
Induction of remission in ALL Vincristin 2 mg/M2 / week In 4 doses IV
Prednisone 2 mg/kg / day 4 weeks Oral
Induction of remission in AML Cyticin arabinoside 100 mg/M2 / day 7 days IV
Daunorubicin 45 mg/M2 / day 3 days IV
Autoimmune thrombocytopenic purpura
Acute AITP Prednisone 2 mg/kg / day Orally
Chronic AITP Prednisone 60 mg / day
Polycythemia Vera
Myelosuppressive drugs hydroxyurea 2 mg / day
Busulafan 2 mg / day

Nephrology
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Indications Drug Dose Every For Admin Note
Post-streptococcal glomerulonephritis
Corticosteroids Prednisone (In children) 2 mg/kg / day 10 days Then gradual decrease over 4-8 weeks
Prednisone (In adult) 20-30 mg / day 2-3 weeks
Diuretics Frusemide 40 mg / day
Dihydrochlorothiazide 25 mg / day
Spironolactone 100 mg / day
Chronic renal failure
Symptomatic treatment (for acidosis) NaHCO
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3 gm Tds Orally May be given IV in severe cases
Acute pyelonephritis
Specific treatment Ampicillin or Amoxycillin 500 mg / 8h 5 days
Co-trimoxazole 2 tablets / 12h 7 days
Ofloxacin 400 mg / 12h 5 days
Acute renal failure (pre-renal)
Induction of diuresis Frusemide 10 amp.(amp=40mg) in 100 ml glucose 5%
Mannitol 500 ml in 25% solution In 30 min IV infusion
Hyperkalemia
Intracellular shift Regular insulin 20 U
IV infusion Combination of both
Glucose 50 gm
Calcium gluconate 10 ml of 10% solution IV very slowly
Cation exchange resins Kayexalate 20 mg tds

Endocrinology
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Indications Drug Dose Every For Admin Note
Acromegaly
Medical hypophysectomy Bromocriptine 30 mg / day
Synthetic somatostatin 100 μg / 8h
Addison’s disease
Replacement therapy Cortisol 30 mg / day Orally To be increased in stress
Fluorocortisone 0.1 mg / day
Addisonian crisis Hydrocortisone 200 mg IV Then
100 mg / 6h IM Till GIT manifestations stop
Dioxycorticosteroid acetate 10 mg IM
Hyperparathyroidism
Treatment of acute hypercalcemia Calcitonin 200 U / 6h IV
Prednisolone 50 mg / day
Tetany
Treatment of the attack Ca gluconate 10 cc of 10 % IV slowly
In between attack Ca lactate 2 gm tds Orally
Vitamin D (calciferol) 50,000 U / day Orally
AT 10 0.5 mg / day Orally
Myxedema
L-thyroxin (Eltroxin) 50 mcg / day Increased every 2 weeks by 50 mcg, average maintenance dose is 200-300 mcg/day for life
Diabetes mellitus
Diabetic ketoacidosis Soluble insulin 20 U initially then 6 U/h IM
6 U initially then 6 U/h IV
KCl 20 mmol / litre of infused of fluid
Sulphonylureas Doanil 2.5-20 mg / day Orally
Amaryl 1-9 mg / day Orally
Biguanides Metformin 500 mg tds Orally
Phenformin 25 mg tds Orally
Insulin Insulin 20-30 μg / day 2 daily injections Increase by 5-10 μg/day




Special Thanks to
Ali HD
 
 
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More Than You Dream
4 Drugs in Medicine
Infections
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Indications Drug Dose Every For Admin Note
Typhoid fever
Specific treatment Ciprofloxacin 500 mg / 12h 10 days Orally Not in children, old, pregnant, lactating
Chloramphenicol
50 mg/kg / day Orally Till fever subside
25 mg/kg / day Orally For rest of 2 weeks
Ampicillin 4 gm / day 2 weeks Orally
Cotrimoxazole 2 tablets / 12h 2 weeks Orally
Brucellosis
Specific treatment Tetracycline 50 mg/kg / day 2 -3
weeks
Orally
Together
Streptomycin 1 gm / 12h IM
Doxycyclin 200 mg / day
6 weeks
Orally
Together
Rifampicin 600 mg / day Orally
Meningococcal meningitis
Chemoprophylaxis Rifampicin 600 mg / day 3 days Orally For close contact
Curative Cefotaxime 1 gm / 8h IV or IM
Till CSF culture results Crystalline penicillin 4 million U / 6h IV
Chloramphenicol 1500 mg / 6h IV or IM
Cholera
Chemoprophylaxis Tetracycline 250 mg / 6h 3 days Orally
Curative Tetracycline 250 mg / 6h 5 days Orally
Malaria
Chemoprophylaxis Chloroquine 500 mg / week 2 weeks Before Orally If no Chloroquine resistance
Mefloquine 2500 mg / week 6 weeks after Orally If Chloroquine resistance
Schizonticidal drugs as curative measures
Chloroquine
4 tablets (1gm) Orally Then
2 tablets (500 mg) After 12h Orally
2 tablets (500 mg) / day for 2 successive
days
Orally
Quinine 600 mg tds 7 days Orally Followed by 3 tablets of Fasindar
Fasindar 3 tablets Once Orally Following 7 days of quinine
True causal prophylactics for curative Primaquine 15 mg / day 14 days To prevent relapses for BTM
Giardia lamblia
Metronidazole (Flagyl) 250 mg tds 5-10 days
Tinidazole (Fasigyn) 2 gm / day 5 days
Aterbine 100 mg tds 5 days
Ankylostoma duodenale
Ascaris lumbricoides
Enterobium vermicularis (Oxyuris)
Flubendazole (Fluvermal) 200 mg / day 3 days In enterobius:
All family members treated at same time
Second dose is given after 2 weeks
Thiabendazole (Mintezol) 25 mg/kg / day 2 days
Pyrantel pamoate (canbantrins) 11 mg/kg Once
Levamisole (Ketrax) 150 mg Once
Piperazine 3 gm Once In ascaris
Piperazine 300 mg / day 7 days In enterobius
Filariasis Diethyl carbamazine (Hetazan) 2 mg/kg tds 3 weeks
Tenia solium, Tenia saginata Yomasen 2 tablets X 500 mg Followed after 1 hour by 2 tablets
Atebrine 10 tablets X 100 mg Followed by saline purge
Hymenelopis nana Yomasen 2 gm / day 5-10 days
Atebrine 1 tablet X 100 mg tds 5-10 days
Bilharziasis
Antibilharzial drugs Praziquantil (Biltricid) 40 mg/kg Single dose Orally For hematobium & mansoni
Metriphonate (Bilarcil) 10 mg/kg / 2 weeks 3 times Orally For hematobium only
Oxamniquine (Vansil) 60 mg/kg Divided on 3 days Orally For mansoni only
Niridazole 25 mg/kg / day 7 days Orally For hematobium & mansoni, not used
Strongylides Thiabendazole 25 mg/kg tds 2 days Orally
Trichuris Trichiura Mebendazole 100 mg tds 3 days Orally
Trichinella spiralis Albendazole 400 mg tds 7 days
Fasciola hepatica Triclebendazole 10 mg/kg Once
Heterophyes Heterophyes Praziquantil 40 mg/kg Once

Rheumatology
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Indications Drug Dose Every For Admin Note
Gout
Treatment of acute attack Colchicine 1 mg / 6h 1 week Stops if diarrhea occurs
Indomethacin (or diclofenac) 50 mg tds 2 days Then half the dose for 1 week
Long term therapy Allupurinol 300-900 mg / day
Probenecid 1 mg / 12h
Rheumatoid arthritis
Anti-inflammatory drugs Aspirin 3 gm / day
Indomethacin (or diclofenac) 75 mg / day
Peroxicam 20 mg / day
Celecoxib 400 mg / day
Paracetamol 3 gm / day
Prednisone 5 mg / day
DMARDs Chloroquine 250 mg / day
Sulphasalazine 1 gm / 12h
Gold salts (auranofin) 6 mg / day Orally
Gold salts (aurothiomalate) 50 mg / week IM
Methotrexate 5-15 mg / week Orally
Penicillamine 250 mg / day Orally
Systemic lupus erythematosus
Medical treatment Chloroquine 250 mg / day
Prednisone 30-60 mg / day For few weeks then gradual decrease to 5-10 mg/day




Edited and designed by
Mohamed El Far