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Umm Al-Qura University

Faculty of Pharmacy

Bachelor of Pharmacy
(B. Pharm) Programme

2008

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Table of Contents
Faculty Vision: .............................................................................................................. 3
Faculty Message: ......................................................................................................... 3
Curriculum and teaching methods at the Faculty of Pharmacy:.................. 3
Degree that is currently granted by the faculty: .............................................. 3
Programme for the degree of Bachelor of Pharmacy (B. Pharm): .............. 3
General and Basic modules for Pharmacy .......................................................................... 5
Department of Pharmacology Modules ............................................................................ 52
Department of Pharmacognacy Modules .......................................................................... 79
Department of Pharmaceutics Modules ............................................................................ 88
Department of Clinical Pharmacy Modules .................................................................... 112
Department of Pharmaceutical Chemistry Modules ........................................................ 130
Elective Modules ........................................................................................................... 150
Table for B. Pharm Programme (Table-1) ...................................................................... 168

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Faculty Vision:
To acquire skills and achieve global standards in the field of pharmaceutical education and
scientific research and development capabilities of innovation and development and to adapt
to each service's goals for the pharmaceutical sector in all areas.

Faculty Message:
The Faculty of Pharmacy at Umm Al-Qura University is established on the basis of an
education programme which has been prepared at the highest levels for graduate pharmacists
and experienced professionals, to achieve an effective role in the areas of health care and
manufacturing medicines, analysis and quality control. The programme gives graduates the
necessary foundations for the development of pharmaceutical information and update
standards for the exercise of the profession of pharmacy achieve optimal use of medicine and
use it and rationalise consumption so as to reach the best level of health of Saudi society and
these can be achieved by:
1. Education, training and maintaining the specialised pharmacists graduate of a
high level of skill and to transfer, innovate and deal with the modern
information based on research evident in the pharmaceutical sciences, social
and clinical, to improve and facilitate the form of life through good health of
the community.
2. Modernise and develop pharmacy practice.
3. Establish exclusive programmes containing scientific and professional
education to student who will be the efficient and effective pharmacist.
4. Granting the degree of Bachelor of Pharmacy, which makes the student able to
understand the basic of pharmacy education.
5. Graduate qualified students with granted intensive pharmaceutical information
and sciences related to pharmacy, and giving skills in scientific research to
perform their role in higher education, government services, manufacturing
medicine and health care.
6. Grant programmes in the optimal use of medicine, rationalize consumption and
avoid its adverse effects.
7. Establishment and development of research programmes access to recent
research objectives that correspond to the strategy and meet the needs of health
care in the community as a whole, and also meet the skills required for the
practice pharmacists and other health disciplines.
8. Develop a sense of responsibility and professional ethics and continuing
education pharmacist.

Curriculum and teaching methods at the Faculty of Pharmacy:
Language of teaching is English. Teaching method at faculty of pharmacy at Umm Al-Qura
University is based and applied on latest scientific techniques in teaching.

Degree that is currently granted by the faculty:
Faculty of Pharmacy currently grants a bachelor degree in Pharmacy (B. Pharm).
Duration of study: five years.
Studying system: two semesters annually.

Programme for the degree of Bachelor of Pharmacy (B. Pharm):
Duration of the study for programme B. Pharm is five years, two semesters annually. Total
modules of the degree is 178 credit hours (Table 1), in addition to the 640-hour summer
training that is applied after the third and fourth academic years.

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These departments are: 1. These departments provide the proper modules for B.Table-1: Total credit hours for a Pharm D. Department of Pharmaceutics 4.6 Sciences Total 219 100 There are five departments at the faculty which provide high quality teaching at all the programme's levels.7 Fundamental Pharmaceutical 46 25.9 English Language 12 6. Department of Clinical Pharmacy 5. Department of Pharmacognosy 3. Pharm programme at Umm Al-Qura University as will be described on the following sections. Department of Pharmacology 2. Graduation requirements Number of units Percentage (%) University requirements 21 11.8 Sciences Specialist Pharmaceutical 99 55. degree. Department of Pharmaceutical Chemistry 4 .

Umm Al-Qura University Faculty of Pharmacy General and Basic modules for Pharmacy 2008 5 .

Topics to be covered include: alkanes. hydrocarbons. aldehydes.Biochemistry Part Description: Chemistry is the study of composition of substances and the changes that undergo. hydrogenation. with particular attention to trace elements. along with changes that matter undergoes. and their reactions with one another. Important areas of organic chemistry include polymerization. units. The most important concepts of physical chemistry include: the interpretation of atomic and molecular structure. I. and stereochemistry. analytical. There are many divisions in chemistry such as general. Density. In quantitative analysis the exact weight of each constituent is obtained as well. and composition. The role of active groups of compounds will be pointed out to demonstrate their clinical importance in designing drugs for diseases. stereoisomerism. Atomic weight and molecular formulas and their relations to the calculation of drugs dose. ketones. physical. Topics will include measurements. halogen compounds. organic and biochemistry. the study of fundamental particles of matter. The course will cover the basic principles of chemistry. V Biochemistry Biochemistry is the study of the molecules and. aromatic. In qualitative analysis all the atoms and molecules present are identified. atoms. Types of solutions will be studied and their clinical use as intravenous solution will be highlighted such as normal saline and dextrose. specific gravity and their relations to urine analysis. Approach to Medical Sciences Course Code: 1000101 Credit Hours: 6+2=8 Academic Level: First Year I . IV Physical Chemistry This branch deals with qualitative (observational) information in quantitative terms. alcohols. II General Chemistry Chemistry is one of the fundamental physical sciences dealing with the structure and properties of matter. alkenes. Organic Chemistry Organic chemistry is defined as the chemistry of the compounds of carbon. ethers. summarisation. It is the branch of science concerned with the properties. application of thermodynamics and the various energy demands in diseases such as cystic fibrosis and hypothyroidism. carboxylic acids and nitrogen compounds. alkynes. their chemistry in 6 . structure. III Analytical Chemistry It is a collection of techniques that allows exact laboratory determination of the composition of a given sample of material. moles.

lipids.g. proteins and nucleic acids. Biochemists study the elements.Chiral Compounds.ionization of water. Parts per million. Types of Solution. Types of Chemical Transformations in cells. Optical Activity. diabetes. atherosclerosis . Difference between Chirality and Optical Activity. Lecture 8 . and disease reflects abnormalities in bimolecules (e. Gout). Functional Groups.The Mole . Lecture 7 :.Chemical Reactivity. reactions that facilitate the processes in a living system.Analytical Chemistry Lecture 9: Classification of Particles. The role of enzymes will also be thought in diagnosis of diseases such as that of liver. -To understand the scientific method as it pertains to biochemistry -To understand the roles of biomolecules in living organisms. cardiac and muscle. such as carbohydrates. saliva and urine. Lecture 5: . molecular genetics. Significant figures. precision and accuracy. Molality. Osmolarity. Solubility and Expressions of Concentration. Bronsted and Lewis Concept of Acids and Bases. a harmonious balance of biochemical reactions occurring in the body.Principles of Organic Chemical Reactions Lecture 4: . Mole Fractions.Avogadro’s number. Acid and Base ionization constants.Definition. interstitial fluid. health and disease (medicine).Atomic number.General Chemistry Lecture 6 : . II.International System of Units (metric system). Percentage Composition. Health depends on. Self. pKa and pKb 7 .g. -To understand the role of biochemistry in modem biotechnology. Types of Stereoisomers. Contents: I. Classification of Organic Compounds. Objectives: To gain an understanding of the principles of chemistry as they apply to living organisms. -To develop basic laboratory skills and techniques for the study of biochemistry and laboratory medicine. Lecture 10: Molarity. Normality. The role of active groups in drugs. Organic Chemistry Lecture 1: Introduction to the course Lecture 2: . compounds and chemical reactions that are controlled by enzymes and take place in all living organisms. blood bicarbonate Lecture 11: -Arrhenius. Empirical and Molecular formulas and their relations to the calculation of drugs dose. pH concept. Parts per billion. Ionic Strength and their relations to blood chemistry e. Rules for Naming the Organic Compounds Lecture 3: . Ill. Atomic weight. It is focused on the structure and function of cellular components of bimolecular. pH of biological fluids as blood plasma.

Lecture 24: Properties and structure of amino acids. Physical and Chemical properties of Monosaccharides. Internal Energy. bicarbonate buffer). sodium bicarbonate reabsorption.Lecture 13 : Buffer Solutions ( e. Lysosomal storage diseases. Isomerism of Fatty Acids. phosphate buffer. Clinical Aspects: Glycogen storage diseases.Physical Chemistry Lecture 14: .Energy Changes in Chemical Reactions. Lecture 22 : Structures of Disaccharides. the standard free energy. Classification of carbohydrates . hypothyroidism. Enthalpy. Lecture 25: The composition of protein. Prostaglandins.g Cystic fibrosis. Lecture 26: Amino acid sequence of polypeptide chains can be 8 . pKa values for amino and carboxylic acid groups attached to central carbon. IV. differences in size. Biomedical importance. ion-exchange. acetate buffer. Lecture 18: Compound Lipids. Lecture 19: Structure and Functions of Glycolipids. Blood Buffers and the major roles of the kidneys in blood buffering.Lipids of Physiological Significance: Lecture 16: Definition. The charge of proteins . III. lipid Peroxidation. and Waxes.g. Biomedical Importance. electrophoresis. Clinical Correlations: Lysosomal storage diseases. excretion and ammonia secretion. Lecture 17: Structures. Lipid storage disease. Ionization of the basic structure. Classification of Fatty Acids. Classification of amino acids.Structures.The Gibbs free energy. Structure and Functions of Lipoproteins. form basis of separation by gel filtration. The size of proteins.Biochemistry 1. 2. Physical and Chemical Properties of Fatty Acids. The various energy demand e.determined by their amino acid composition and exploited as a basis of their separation e. Lecture 21: Isomerism in glucose.Carbohydrates of Physiological Significance: Lecture 20 : Definition. Denaturation. Steroids and Sterols. Functions of polysaccharides. acid. isoelectric point of amino acids and peptide bonds. energy and maximum work. Classification of proteins according to biological functions.. Structure and Functions of Phospholipids. Lecture 15: .g. Physical and Chemical Properties of triacylglycerols. Acidosis and Alkalosis (respiratory and metabolic). Concept of first and second law of hermodynamics. Entropy. Functions of Disaccharides Lecture 23 : Structare of Polysaccharicles.

Preparation of solutions (Weighing of solids. Factors-affecting rate of reaction. Allosteric enzyme regulation. 5. 7. Cleaving the polypeptide chain. Percent solutions). 4. Lecture 27: Amino acid sequence is primary structure of a peptide or protein. creatinine.Menten Equation. Covalent modification by phosphorylation. Halides). Ketones. Ionic properties of amino acids. Properties of Buffers. Reversible Inhibitors and irreversible inhibitors. Acid — Base Titration . Sequencing of peptides. beta-sheet and beta-turn). Eva fuation methods. 8. uric acid to assess kidney function. Introduction to the Biochemistry Lab. Acid — Base Titration . Identification of organic compounds (Alcohols.Enzymes: Lecture 28 : General featuies of enzymes. . Safety precautions. determined. Lecture 30: Enzyme inhibitors. 3. 9. Enzymes in clinical diagnosis: Liver function tests.(II). Mechanistic Principles of Qualitative Identification of Carbohydrates-2. Copper acetate. Regulation enzyme activity. Preparation of Buffers 12. Esters). Calculation of Km and Vmax for one substrate and two substrate reactions are related to clinical analysis of enzymes in body fluids. Cholesterol).Tyrosinemias alcaptonuria and Maple syrup urine disease. Cardiac enzymes.(I). Norma!. tertiary structure. Unsaturation. Ordering peptide fragments. Disposables 4. Lineweaver-Burk Plot. 14. globular protein and fibrous protein. secondary structure (alpha helix . Large proteins must be sequenced in smaller segments. Metals. 13. Practical: 1. Measuring liquid volumes). Introduction to Coenzymes. 2. Lab conduct. Qualitative analysis of lipids (Grease Stain. Competitive and noncompetitive inhibitors. Mechanistic Principles of Qualitative Identification of Carbohydrates-1. Classes of enzymes. 6. 9 . Identification of organic compounds (Phenol . Containers: Glassware. Lecture 29: Enzyme kinetics. mechanism of enzyme action. 15. Clinical correlation of amino acids: Aminoacidurias. Micbaelis . Preparation of solutions (Expression of Concentrations: Molar. Plastics. urea. 10.Aldehydes.Ethers. Introduction to the commonly used instruments in the laboratory. quaternary structure. Albumin. 11.

Bishop. Keith Wilson. Wernhe 2002 ISBN: 3-527-30299-9 2. • The relationship between Man & his environment so as to identify the place of human physiology in the study of medicine as a health & social science. P. Bayer. 2002 5. Procedures Correlations (5th edition. Biochemistry Extended Chapters 1-34 Lubert Stryer. MT(ASCP). Jeitsch. Lecture NO. 2004) ML. Hoggett. 4. Biochemistry Laboratory: Modern Theory and Techniques Rodney F. Predict the e of disease processes on the normal functions and how the body responds & compensates for such disturbances. Contents: Lecture NO. Wily-VCH VertagG. 2005 II . students are expected to be able to: 1. 3. Protein size and separation (Gel Chromatography).E.mbH. Principles and Techniques of Biochemistry and Molecular Biology. Urbanke. L. 17.1: • Introductory lecture Definition of physiology. J. Clinical Chemistry: Principles. Jeremy Mark Berg. References: 1. A. Tymoczko.Physiology Part Objectives: At the completion of these physiology courses. John Walker (2005). John L. Recognize the role and basic underlying principles of the different body systems in regulating the internal environment. 16. Enzyme activity. Schoeff. Cambridge University Press 3. Fody. E. Acquire preliminary skills in using laboratories and bedside techniques commonly encountered in clinical practice. 2. 5. CLS(NCA). List the normal values of important physiological parameters and interpret such values when given. Biochemical Methods: A concise guide for students and researchers. C. MT(ASCP ISBN: 0781746116 4.2: 10 . Pingoud. • The functional organization of the organ systems of the human body in order to develop a holistic approach to the study of medicine. Explain how different body systems achieve their functions and how these functions are regulated and interrelated.

Lecture NO. Lecture NO. & renal systems in acid . Lecture NO. • The thermal balance.8: • The regulation of body temperature. • The role and the basic underlying of principles of different body systems in regulating the internal environment.3: • The specialized organdies in eukaryotic cells and their physiology.7: • De of the control systems & their properties.6: • The membrane concept. Lecture NO. Lecture NO. Lecture NO. • Abnormal conditions in relation to disturbances of body fluid & electrolytes i. • The structure & function of the animal (human) cell.e. Lecture NO. heat stroke. tight and gap junctions.in disease processes.12: • The role of buffers. & heat exhaustion.9: • The normal composition of the human subject including . • The components of the control systems. & minerals.10: • The basic principles of forces for movements of fluids & electrolytes across the biological membranes. desmosomes.lipids. Lecture NO. respiratory. • The biological membranes as lipid bilayers . proteins . such as dehydration. & the membrane proteins and their function. edema.& hypo-osmolarity & acid base balance.4: • Physiological review of cyto skeleton.5: • The cell junctions and their role in transport.base 11 . • Definition of homeostasis. & the related abnormalities such as fever. • The concepts of the internal environment & its constancy as an important condition for normal health. Lecture NO. hyper.11: • Define the pH & identify the normal range of pH of the body & how it is regulated. water. Lecture NO.

particularly that of the nerve & muscle. • The electrocardiography (ECG). the autonomic versus somatic & the central versus peripheral nervous systems.14: • Definition of metabolism (catabolism& anabolism)& the mechanisms. Lecture NO. neurotransmitters.13: • The relationships between the body electrolytes & acid base disturbances. Lecture NO. 12 . Lecture NO. Lecture NO. Lecture NO. sympathetic.20: • Nutrition: Digestion & absorption of carbohydrates. • The receptor organs • The second messenger system. blockers & its functions.out flow.16: • Nutrition: Digestion & absorption f lipids Lecture NO. parasympathetic. Lecture NO. balance.19: • Ionic basis of the resting membrane & action potentials of the cell membranes.22: • Organization of autonomic nervous system.23: • The sympathetic nervous system . the motor versus sensory . Lecture NO. Lecture NO. involved in energy consumption. • Synaptic transmission.21: • General organization of the nervous system.& the enteric nervous systems.15: • Definition of the basal metabolic rate (BTVfR) & the factors that (affect) or regulate it. the electromyography (EMG) & the electroencephalography (EEG).18: • The basic properties of cell membranes which underlie the process of excitation. • The regulation of receptor activity. Lecture NO. Lecture NO.17: • Definition and basic properties of the cell receptors.

cell mediated & acquired immunity.26: • Types of muscles. compare & contrast the effects of benign & malignant tumors. 5. neuro- transmitters.25: • Nutrition: Digestion & absorption of protein. To study the structure of a plant cell (onion cell). 13 . 11 study the process and rate of diffusion. 13. 14. 2. Lecture NO. To study the effect of iso. sensory absorptive functions & regulation of body temperature. 6. causes of death in malignant disease. Lecture NO. To study the different parts of a compound microscope. To measure diameter of different blood cells. To measure the body temperature. To measure microscopic objects using stage and oculomicrometer.29: • Disorders of the cells & tissues : common causes of tumors. Lecture NO. To observe pupillary light reflexes.28: • The major physiological functions of the skin including secretory . 12. Lecture NO. To prepare and study a temporary wet mount.30: • Non specific defense mechanisms. 8. 9. Lecture NO. hyper sensitivity & autoimmune diseases. blockers & its function. hypo and hypertonic solutions on the size. • The molecular basis of contraction & relaxation of muscle fibers in order to explain the links between the electrical & mechanical events. To prepare and study a temporary dry mount. 7. out flow .protective.24: • The parasympathetic nervous system. Lecture NO. To study the structure of a human cell (cheek cell). Practical: 1. To measure macroscopic objects.27: • The microscopic anatomy of the skin & their functional significance. To study the different staining techniques. 10. To measure the basal metabolic rate. 4. 11. Lecture NO. of the cells (RBCs) as an example. 3.

o RNA-directed DNA synthesis. To prepare a nerve muscle. References: 1. o Regulation of gene expression: control of transcription. Biology by Solomon. o Translation: transfer RNA. o DNA: the hereditary material composition. Villee. Martin. Mitochondrial DNA. 3. 2. 16. 19.1: o The cell. • Lecture 2-4: o Types of DNA sequences: Nuclear genes.al. Nutrition : Digestion of proteins. transcriptional factors. Extragenic DNA. 17. structure. 15. preparation using frog. functional effects of mutations on the protein. To study the different parts of a kymograph. o Transcription: Post-Transcriptional processing. post-transcriptional control of gene expression. To study the effects of stimulation of the autonomic nervous system by determination of the heart rate and pulse rate during rest and after exercise. Nutrition: Digestion of lipids. 18.Y. structural effects of mutations on the protein. Concise Human Physiology by M. 4. o Mutagens and mutagenesis: Mutagens. Textbook of Physiology by Elaine & Marieb. DNA repair. o The genetic code: Triplet codons. Sukkar et. genotype-phenotype correlation. Berg. o Chromosome structure. • Lecture 5-7: o Mutations: Types of mutation. Anatomy & Physiology in Health &Illness by Ross & Wilson III – Human Genetic Part Contents: LECTURES 1-7: TEE CELLULAR AND MOLECULAR BASIS OF INHERITANCE: • Lecture . 21. s sciatic nerve & gastronemius muscle. replication. To record skeletal muscle contraction with the help of a kymograph. Nutrition: Digestion of carbohydrates. 20. 14 . Post-Translational Modeification.

meiosis. o Chromosome abnormalities: Numerical abnormalities. the sex chromosomes. o Gameto genesis: Oogenesis. spermatogenesis. the cell cycle. o Cell division: Mitosis. structural o abnormalities. 15 . o Mosaicism and chimerism (Mixoploidy). classification.LECTURES 8-15: CHROMOSOMES AND CELL DIVISION: o Human chromosomes: morphology.

The demand for prescription and nonprescription medications. The present course provides basis for the budding pharmacy student. the student never understands the bigger picture of how all the pieces fit together. and this trend will likely continue. so that the student will know better what a certain term means or what an issue is all about. controlling its cost. the past. expanded responsibilities. First Semester Description: The practice Pharmacy is a vital part of a complete health care system. and concerns about improving patient’s access to health care. they are presented with the opinion and viewpoints of dozens of faculty members. pharmacist will have an important role in the future of health care. organized. or staffed in such a way that pharmacists can routinely apply themselves to the prevention of medication errors and misadventures.of facts. Due to many of society’s changing social and health issues. 2. Because of the large role that medications and their proper use play throughout these issues. textbooks and the intricacies of thousands. The number of people requiring health care services has steadily increased. This can begin only when the student has developed an accurate view of the profession he or she is entering and has come to understand the basic tenets of the profession and critical issues it is now facing. the student is expected to undergo a process known as professionalization.Medication errors and drug related problems are well documented as massive crises involving the loss of thousands of lives and high compensation paid by medical insurance and pharmacist theoretical could prevent a sizable fraction of these.High prices for Pharmaceuticals and wild spreading of life threatening illness created burden for low-level income population to provide required medicine for health care. in advance. amidst the cadence f all this information. but a number of threats to the profession are now clear including: 1. the perspective and outlooks of hundreds of article journals. the increased complexity number. followed by overview on past development including global contribution to pharmacy. and long-term care.has never been greater. the increased emphasis on primary and preventive health services. The purpose of this course “Approach to Pharmacy profession” is to provide a simple framework.and for the pharmacists who provide them. As student pass through the years of undergraduate education in faculty of Pharmacy.some would say millions. During the Pharmacy study program. present status and prospective tasks. Some of these issues include increases in average life span and the increased incidence of chronic diseases. home health care. Orientation to pharmacy course is performed. Sometimes. However conventional pharmacy is not designed. Approach to Professional Pharmaceutical Sciences Course Code: 1801246 Credit Hours: 1 Academic Level: Second Year. men and women in pharmacy will face new challenges. Health official generally do not 16 . and assuring its quality. and sophistication of medication and related products and devices. and ever increasing growth in opportunities.

or treatment of disease. Over all care programs involve disease managements based on pharmacists. academic activities. drug information units and poisonous centers by explaining task and responsibilities. The managed care pharmacists often work directly with physician and other care providers to determine which medical treatments. The primary focus of this course is to familiarize students with prototypes for the major Pharmacy major syllabus subjects. managed care pharmacist review drug utilization to determine which patients and prescribers are using particular medications. the pharmaceutical industry. In addition the course emphasized possible professional career of Pharmacists including managed care health service. the pharmaceutical industry. Contents: Lecture – 1: • Introduction to Pharmaceutical sciences. realize yet that pharmacists could help with such problems. This course addressed these challenges in an effort to achieve the ultimate role of the pharmacist in society by assuring appropriate.Iraq peninsula 3500 BC. 3. cure. valued and efficient from cost prospective. • Concept and tools of treatment. physicians and health staff working as team with full coordination for effective achievements. This course addressed challenges in an effort to achieve the ultimate role of the pharmacist in society by assuring appropriate. The course covers these aspects by illustrative case presentation and student integrative response. In addition the course emphasized possible professional career of Pharmacists including managed care health service. Objectives: The Pharmacy profession course is designed to acquaint students with the basic principles of pharmacy development as profession over the time.Internet is a very efficient ways to get medication to peoples and it is increasing as service to substitute conventional ways with variable rate and depending on high tech application. are most effective in enhancing patient outcomes. • Source of Pharmacy knowledge from early days of man existence on globe. including which drug therapies. cure. and the safe use of medication for the prevention. implementation of 17 . or treatment of disease. Some critics believe this makes medications seem like any other commodity and reduces people’s perceptions of pharmacy as a professional service. pharmacists will have to prove beyond any doubt that their services are needed. This new service reduces the personal. academic activities. and many physicians discount this possibility. Consequently. face-to-face contact people have with their pharmacist. • Four sources have been presented with examples. drug information units and poisonous centers by explaining task and responsibilities. Lecture – 2: • Ashorian contribution. In addition. goal and developments of pharmaceutical care. and the safe use of medication for the prevention.

Al-Kiandy 800 —871G. Theophraste. Thabat Bin Qura 859 —90 1G. • Arab in early Islam Women role in ware casualty treatment • Islamic era and Pharmaceutical contribution. • Persian contribution 521 to 486 BC. • Chinese contribution 2900 BC. implementation of pharmaceutical agents and its formulations. implementation of pharmaceutical agents and its formulations. Ibn Sina 1037G.Concept and tools of treatment. Concept and tools of treatment. implementation of pharmaceutical agents and its formulations. Gensung etc. • Egyptian contribution 2200 BC • Concept and tools of treatment. Erman and Chester Betly. Sabour bin Sahal Al-Kosag 869G. Dicles de Carystos. E. Lecture – 4: • Indian Contribution 2500 —1500 BC. Hippocrate. Lecture – 6: • Arab before Islam. abbasaid Term — Uhana Bin Masawai 777 — 857G.Ibn Hazeim. implementation of pharmaceutical agents and its formulations. AiHareth Bin Kelda and others. G. implementation of pharmaceutical agents and its formulations. pharmaceutical agents and its formulations. Concept and tools of treatment. implementation of pharmaceutical agents and its formulations. DeRemedica a drug book by Celsus. Abu Baker Al- Razi 865 932G. • Eastern Muslim term — Umaid Term. Platon. Concept and tools of treatment. implementation of pharmaceutical agents and its formulations. Samhita Pharmaceutical encyclopedia containing 700 drugs including Rawolfia Serpentina. Smith. Egyptian Payrus — Kahun. Lecture – 7: • Muslim Golden Term • Ali Bin Sahal Rabin Al-Tabari 775 — 869G. Hearst. Ali Ibn Abbas 360H.Concept and tools of treatment.. Hanian Bin Ishak 809 — 877G. • Roman contribution. 18 . Lecture – 5: • Greek.Latin contribution. Materia media of Galinus. Avesta Pharmaceutical encyclopedia. Aristote. • Concept and tools of treatment. Pen Tsao Kang 1578 a Pharmaceutical encyclopedia containing 365 drugs including Ephedra. Lecture – 3: • Jewish contribution — their accumulated experiences in Ashorian and Egyptian areas. Ebers.

Lecture – 8:
• Western Islamic Term contribution to Pharmacy.
• Ibn Al-Jazar 920 - 1 005G, Ibn Jalal 976 - 1 009G, Abu
Quasses Al-Zahrawy, 936 - 1013G, Overview of Golden
achievements by Muslim in Pharmaceutical field including Al-
Hesba.
Lecture – 9:
• Pharmacy requirement of 19 century.
Lecture – 10:
• Pharmacy requirements of the twentieth century- Charles
helper declaration for change in Pharmacy profession,
Pharmaceutical care as reprofessionalization.
Lecture – 11:
• Criteria for successful professional Pharmacists Pharmacist and
drug preparation.
Lecture – 12:
• Pharmacist new responsibilities and skill requirements
Lecture – 13:
• Pharmacist New services, Pharmaceutical planning for change.
References: • Opportunities in Pharmacy careers: by Fred B. gable. National
textebook Co, Lincoinwood.
• Employment outlook for Pharmacist: Us governmental
publication, Washington, DC.
• Pharmacy Career planning and professional opportunities;
edited by Donald Rucker.
• Pharmacy career opportunities: Published by Merritt
communications Inc.
• Online Resources:
• http : comletsu This monthly publication provides current
drug information in a newsletter format with access to related
articles.
• http://www.lib.lsu.edu/sci/pharmacy.html
• http ://atsdr.edc. gov/toxfag.html
• http://pharminfo. corn

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Learning Skills
Course Code: 1000112
Credit Hours: 2
Academic Level: First Year
Description: It’s a course designed for first year medical students as well as health
sciences students. It is established by Dr.Hani Al-Moallim on 2005.
This course is accredited by the college & has a credits hours of (2)
units.
There will be (8-9) lectures & workshops in the course (2 hours per
week) which will be given by INTERNS & SENIOR STUDENTS.
The Assessment Methods:
1. Students project (Seminar) :

The subject of the presentation is selected by the students and
approved by their supervisors. Any scientific topic can be chosen
(preferably related to medicine and learning).
v The project consists of 3 parts:

ü Attendance: Each student must visit the supervising doctor 3
times during the course (in his office or any appropriate
place).The time and place of each visit will be determined by
the supervisor and his group according to what is appropriate
for them.

ü Assessment during the course: Each student must be
evaluated separately. This evaluation will be carried out during
the whole course.

ü Assessment of the presentation: Each student must take a part
in presenting the material (individual assessment).

2. Exams:

There will be one final exam in a form of 40 multiple choice
questions (MCQs) at the end of the course (the duration of the exam
will be 1 hour).
The exam will be open book exam
v Marks Distribution:

o 60 marks on student project (seminar) during the course.

o 40 marks on the final MCQs exam.

3. Attendance :

You should attend all the lectures. In Case of being absent more
than 20 % (2 lectures), you will not be allowed to attend the final
written exam.
4. The References :

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A lecture-note will be prepared for you to help you answering the
MCQs, otherwise : your understanding, participation and interaction with the
tutors will be enough.

Objectives: By the end of this course, first year student should be able:

1. To adopt the concept of continuous and lifelong learning.
2. To develop independent and deep approach to learning.
3. To know how to study and how to prepare for examinations.
4. To develop and improve his/her skills in notes taking, listening,
speed reading, problem solving etc.
5. To acquire basic skills in research and presentations.
6. To know the importance of developing higher mental functions
in sensing like: logical thinking ,problem solving, data
interpretation, and creativity.
7. To acquire the concept of group work & leadership.
8. To get used to dealing with the teaching staff & senior students.

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Mechanics 1-4 Newton’s laws of motion: force. diffraction and polarization. dissipative forces. lenses. General Physics (for medical students) Course Code: 403104 Credit Hours: 2+1=3 Academic Level: First Year. the duration of each is 3 hours. II Sound: 15-17 sound waves and intensities. sound detectors and the human ear. composed of ten practical sessions. refraction of light and the refractive index. second semester Description: This course is aimed for medical students who have just completed high school. image formation. Contents: The distribution of the course contents on the lectures is shown below: I. 2. scaling laws in physiology 12-14 Fluid mechanics: the manometer. viscosity. kinetic and potential energies. density. ultrasound principle. effective weight. the human voice. the simple magnifier. total internal reflection. equilibrium of rigid body. 9-11 Work. The course is based upon (Three teaching units) specified as follows: 1. energy and power: work. Newton’s. 20-23 mirrors. Newton’s third law. the human eye. the power of a lens.A laboratory unit. power. stability and balance. optical defects of the eye. the role of gravity in the circulation. IV Modern physic: 22 . III Light and Optics: 18-19 wave properties of light: reflection of light. friction. the microscope. muscles and levers in the body. weight.Two teaching units represented as two lectures per week. blood pressure measurements using the sphygmomanometer. Newton’s first law. each lecture is 50 minutes long. levers and mechanical advantage. limitations and its destructive effects. lenses and optical systems: mirrors. the center of gravity. 5-8 Static’s: torque. The course is designed to provide basic principles of physics with direct relation to medical applications. second law. flow in the circulatory system.

Practicals: Experiments associated with the course: 1. gamma rays and radioactivity. 7. 1988. 23 . atomic and nuclear structure. radiation in medicine. Wiley.Detection of ionizing radiation 10.Transmission of radiation References: PHYSICS. the wave -particle duality.Refraction of light and the prism 8.n. ionizing radiation.Graphs 2. diagnosis and therapy. X-rays.Levers and pivots 5.Fine measurements 3.Vectors 4.Thin lenses measurements 9. J WKane & MM Sternhei. 24-28 particle and wave properties of matter: the photon.Fluid pressure measurements 6.Frequency measurement of a tuning fork using the sonometer.

Enzyme Structure. Lipid Metabolism 9. the principle metabolic pathways and the basis of their regulation and connections. hormones. amino acid/protein. Amino Acid Metabolism 24 . pathophysiological and biochemical or genetic perturbations as they affect bodily functions. 2. roles of receptors and hormones. Lipids and Membranes 8. carbohydrate and lipid structure and function in the normal and pathophysiological states. Lipoprotein and Cholesterol Metabolism 10. Carbohydrates Metabolism and Energetics 7. Enzyme Cofactors and Minerals 4. Protein Structure and Function 3. the underlying foundation of biochemistry in the treatment of individual diseases. enzyme catalysis and inhibition. Description: The course examining nucleic acid. and carbohydrate and lipid metabolic pathways. Nucleic Acid Biochemistry 12. Course Introduction/Protein Structure and Function 2. Understanding of the basic biochemistry of body constituents including structure. assessment and integration of biochemical information as it relates to desired and unwanted effects produced by therapeutic drugs 3. Other topics include: chemical functional groups important in metabolism. Abilities in the areas of observation and measurement of biochemical compounds and processes. Carbohydrate Structure and Function 6. Function and Regulation 5. the nature of information transfer methods. protein structure/function. Steroid Hormone Biosynthesis and Function 11. First Semester Objectives: 1. Pharmaceutical Biochemistry Course Code: 1805229 Credit Hours: 2+1=3 Academic Level: Second Year. An appreciation of integrated biochemical and physiological functions. Contents: 1. function and classification of the major biomolecules.

by Joshi A. Diastase. SGPT.Practical: 1. 3. Rashmi – 2004. Practice in injecting drugs by intramuscular. References: 1. Detection and identification of proteins. acid phosphatase. A Textbook of Practical Biochemistry. Amino acids. carbohydrates and lipids. by Keith Wilson. creatine. Estimation of free and titrable acidity in urine 5. Experiments devised for identifying and estimating components of different food materials. triglycerides. withdrawal of blood samples. calcium. Principles and Techniques of Practical Biochemistry. urea. subcutaneous and intravenous routes. Bilirubin. Analysis of normal and abnormal constituents of Blood and Urine (Glucose. cretinine. 2. SGOT. alkaline phosphatatase. 4. John M. Lipase). Estimation of chloride and magnesium in serum and urine 6. 25 . Walker – 2000. cholesterol.

To understand the benefit from Microsoft Excel. Train students on power point presentation programme to use it in providing short lectures and also to be used for the work of graphs and multimedia. Definition Windows operating system (windows xp) and focus on organizing files. 5. 9. Train students how to use Microsoft Word. Using bibliography programs such as Endnote and Reference Manager. 6. 3. 4. Train students to use computers in their studies. Scanner use and the long texts entering using scanner. 2. data protection and control panel. Definition of the components of the PC and definition of some techniques that can help in using computer applications. Definition and the use of the Internet browser and programmes added and search engines and some sites of scientific seriousness. Computer Sciences Course Code: 1000113 Credit Hours: 1+1=2 Academic Level: First Year Objectives: 1. 7. One of the most important programmes that identified is Adobe Acrobat. 8. Using scientific and medical database searching programmes. 10. 26 .

review of function and graphs. differentiation and integration of algebraic functions covering all relevant rules. Definitions and examples of differential equations. 4. general review of basic mathematics. Examples and applications from medical and pharmaceutical sciences. 7. 5. exponential functions. Calculus : a quick. Trigonometric functions. logarithmic functions. 6. Math for Pharmacy Course Code: 1803238 Credit Hours: 2 Academic Level: Second Year. Differentiation and integration of the above mentioned transcendental functions. 27 . exponential models. 2. Solving first order differential equations using variable separable method with applications from medical sciences subjects. First Semester Description: A one semester (14 weeks) of two-h ours a week course. Materials covered are as follows without going into abstractions or requiring reproduction of proofs when given: 1. 3.

and sterility. It has 3 credit hours (2 hours lecture and 1 hour practical per week) and completes in approximately 14 weeks. 5. Introduction to bacterial cell morphology and structure.Understand the major diseases caused by microorganisms and the best ways for save pharmaceutical practice. disinfection. growth and metabolism. 10. 7. Protein synthesis. and immunology techniques used in laboratory diagnosis.Reinforce the practical skills in the safe handling of microorganisms. Introduction to mycology. 6. virology and mycology. Bacterial pathogenesis and diseases. Bacterial genetics.Understand methods of preventing and reducing contamination by microorganisms. 9.Achieve fundamentals knowledge about medically important microorganisms. . terms. exchange of genetic information. 4. Infectious diseases transmitted primarily by airborne route. viral structure and replication. Pharmaceutical Microbiology Course Code: 1803239 Credit Hours: 2+1=3 Academic Level: Second. Antibiotics (II). 3. Bacterial nutrition. nucleic acid synthesis and metabolism. Introduction to virology. physiology. Sterilization and disinfection. the study of fungi. Description: This course is offered to 2nd year pharmacy) students throughout the second semester. . 4. first semester Objectives: To enable the student to: 1. 12. This course consists of medical bacteriology. including exercises in antibiotic susceptibility. Antibiotic resistance mechanisms. Infectious diseases transmitted primarily by contaminated 28 . with emphasis on mechanisms of diseases. Culture and identification of common infectious agents. 11. 2. morphology. 8. 3. 2. Contents: Lectures: 1. Antibiotics (I): action against bacterial cell envelope.

Diseases transmitted primarily by arthropods and through wounds. Diseases transmitted primarily by contaminated water or food. Microscopical examination of microbes and Gram staining. 5. Sterilization and disinfection. 13. Antibiotics sensitivity tests (II) 7. 10. 9. Infectious diseases transmitted primarily by direct contact. 2. Diseases transmitted primarily by direct contact. 2) Clinical Microbiology made ridiculously simple by Gladwin. Practical 1. 14. 4. Safety in microbiology laboratories. 8. Culturing of bacterial pathogens. 3. 11. water or food. Infectious diseases transmitted primarily by arthropods and through wounds. References: 1) Medical Microbiology 5th Edition by Murray. Antibiotic sensitivity tests (I) 6. ELISA test. Diseases transmitted by airborne route. 29 .

B Cell Tolerance 7. Pharmaceutical Immunology Course Code: 1803331 Credit Hours: 1+1=2 Academic Level: Third Year. Accurately describe the immunopathology of HIV/AIDS and other acquired and inherited immunodeficiencies. and eukaryotes to establish human infections. 4. The course focuses on the cellular and molecular regulation of the immune system in health and disease. Demonstrate proficiency in immunological laboratory techniques and analysis of experimental results. Peripheral T Cell Tolerance 8. and pathogenic strategies of common human infectious agents. development of lymphocyte repertoires. Contents: 1. development and function of the immune system. Antibody Structure & Antigen Recognition. 3. and biotechnology uses of immunoglobulins. analysis of immune system function. Describe the interactions between the innate and adaptive responses and between the humoral and cellular arms of the adaptive immune system. Cellular Interactions in the Immune System 3. Antigens & Antibody Production 2. Basic Principles & Overview of Immunity. Transmembrane Signaling. 6. Hematopoiesis & B Lymphocyte Development. Accurately describe the cellular and molecular components of the human innate and adaptive immune systems 2. Innate Immunity. Laboratory sessions will include diagnostic bacteriology. Complement 4. Topics include recognition of antigen. 5. Visit clinical and research immunology labs and write a brief paper relating the observations to classroom material. APC Regulation of the Immune Response 30 . viruses. Central T Cell Tolerance. innate and adaptive immune responses. Antigen Receptor Signaling 6. Second Semester Objectives: 1. Description: Introduction to the structure. Antigen Recognition by T Cells 5. Accurately describe strategies used by pathogenic bacteria.

2000. paraproteins 2. radio/enzymoimmunoanalysis. References: Lab manual: Immunology Investigations. Introduction to Infectious Disease 13. Adaptive Immunity to Infection 14. Tumor Immunology 22. Inherited Immunodeficiency Diseases 16. Immunological Memory 12. Methods for detection of autoantibodies – indirect immunofluorescence. immunoelectrophoresis / immunofixation. Batina. Evasion of the Immune Response by Pathogens 15. Production of Effector T Cells. agglutination. 9. acute phase proteins. Theoretical principles of: immunodifusion. Humoral Immune Response & Ab Function Revisited 11. Evolution of the Immune System Practical: 1. precipitation. Immunoglobulins. Complement tests. specific antibodies (against infectious and other antigens). Manipulation of Immune Responses 23. Vaccines 24. Western Blott (WB) 3. Star Publishing Company. IgE and Allergic Reactions. Hypersensitivity Diseases 18. 31 . Tolerance and Response to Self & Non-Self 21. Autoimmunity: Responses to Self Antigens 20. Innate Immunity to Infection. tests of the complement function (including complement inhibitors) 4. Acquired Immune Deficiency Syndrome 17. turbidimetry and nephelometry. ELISA. Mucosal Immunity. Transplant Rejection: Responses to Alloantigens 19. Cytotoxic T Cell Effector Mechanisms 10.

32 . Description: The course is an integrated study of the function. anatomical position. Pharmaceutical Anatomy and Histology Course Code: 1804250 Credit Hours: 2+1=3 Academic Level: Second Year. nomenclature. 3. abnormalities and congenital anomalies. planes. tissues and movements. Considerable emphasis is placed on dissection. gross. 2. He/She should be able to locate the site of gross lesions according to the deficits encountered. Identify the microscopic structures of various tissues. Coursework is designed to meet the diversified needs of those interested in health sciences as well as physical education and biological science majors. structure and interrelationships of the various organs and systems of the human body. To understand the basic principles of embryology including genetic inheritance and stages involved in development of the organs and systems from the time of conception till birth. and organs in the human body and correlate the structure with the functions as a prerequisite for understanding the altered state in various disease processes. Microanatomy and histology Contents: Gross Anatomy Introduction to Anatomy. First Semester Objectives: 1. He/She should be able to explain the developmental basis of the occurrence of major variations. genetic mutations and environmental hazards on it. 4. The subject of anatomy is taught under the following heads : 1. Comprehend the basic structure and connections between the various parts of the central nervous system so as to analyze the integrative and regulative functions on the organs and systems. inter-relationships. Gross anatomy 2. The student should recognize the critical stages of normal development and the effects of common teratogens. functional and applied anatomy of the various structures in the body. Comprehend the normal disposition.

nerve supply. general features of the bone and normal development. maintenance of articular cartilages. ductus deferens. blood supply and nerve supply of the joints. blood supply. extent. 6. Position. prostate. X-rays of bones. structures and body as a whole. Definition and classification of joints. names of the blood vessels and venous drainage of the organs. 7. general features of different types of joints. Arthrology a. testes. Classification and identification of the muscles of the body: main attachments. Parts. relations. nerve supply and lymphatic drainage of uterus. internal features of the chambers of heart. relations. external features and parts of the heart. 33 . its reflection. relations. bronchopulmonary segments.1. parts. 3. blood supply. position. nerve supply and action(s). detailed study of major joints of the limbs and movements performed at various joints in the body. Cardio Vascular System a. vagina. ovary. epididymis. 5. mechanism of the movement caused by the muscle/muscles and various forces exerted by them and their action(s). lymphatic drainage and sphincters of the gastrointestinal system. b. Details of attachments of the muscles. Genito-Urinary System a. their importance. Anatomy of articular cartilage. Digestive System a. ovarian duct. Normal position. ossification of the bones of the limbs for age determination. cervix. Pleura. Muscular System a. Osteology a. pleural recesses and their significance. nerve supply. kidney. 4. Names of the bones of the body and their position. Position. b. seminal vesicle. 2. conducting system of heart. blood supply of upper and lower respiratory tract. classification of the bones with examples. Respiratory System a. parts.

Intercellular substances. neuroglia. abdomen and pelvis to understand the interrelationship of organs and structures. Parts of nervous system. nerve terminals. cell junctions. functions. specialization of the cell surface and their structural details and functions. Course Contents: Four primary tissues: Example given from each type: 1. neuron meninges. thalamus. pleura. Surface features of the body and projection of the outline of heart. ventricles. Lymphatic System a. lungs. Surface Anatomy a. types of connective tissue (loose areolar tissue. Cross sections of thorax. fibers and their structural features and functions. cerebellum. limbic and autonomic pathways. metaplasia. Gross anatomy of the major lymphatics specially thoracic duct and its tributaries. their borders. cranial nerves. kidneys and various abdominal and pelvic organs and important vessels and nerves 12. liver. amorphous ground substance. surfaces and valves. 8. ureter. distribution. spinal cord and its blood supply. degeneration and regeneration.Epithelium : Microscopic characteristics. 10. 9. Motor and sensory pathways. blood supply. fissures and hila. Nervous System and its components a. urinary bladder and urethra. CSF. myelination. nerve supply and lymphatic drainage. its borders. Cross Sectional Anatomy a. types. 2. 11. basal lamina.Connective tissue : Cells. Functional cortical areas. Endocrine System and Individual Endocrine Glands a. dense connective 34 . Location of the major groups of the lymphnodes of the body and their drainage areas. General Histology Cell : detailed structure of cell and its components and their functional mechanisms. their location. relations. Various endocrine glands. motor and sensory cortex and their blood supply.

Practical: Gross Anatomy 1. front back and lateral side of leg and dorsum of foot. Prosected Parts: Perineum including ischio-rectal fossa. degeneration and regeneration in peripheral nerves. Axonal transport. bone matrix. morphological and functional characteristics of different types of synapses. Abdomen: Dissection: Anterior abdominal wall and inguinal region. Upper Limb: Dissection: Pectoral and scapular. structural and functional characteristics of cardiac and smooth muscle. tissue) and their distribution. Thorax : Dissection: Chest wall. Viscera and Posterior Abdominal wall and nerve plexus. lungs. synapse. Specialized connective tissue : different types of cartilages and their functions and distribution. Brief cytoarchitecture of the central nervous system. Different types of neurons and their specific structural and functional features and distribution. Bone : Cells. ossification. Sensory and autonomic ganglia. 2. axillary and shoulder region. their distribution and functions. Palm and dorsum of hand. front and back of thigh popliteal fossa. blood supply of a long bone. blood vessels and nerves. peripheral nerves. structure and functions. 4. Head & Neck: Dissection: Superficial and deep dissection of face 35 . blood brain barrier. axon and dendrties. regeneration in CNS with particular emphasis on stem cells. 3. Prosected parts: Joints. arm. external genitalia. and molecular mechanisms of contraction. morphological and histochemical basis of classification into type I and type II muscle fibers and their significance. innvervation of cardiac and smooth muscle. pleura.Muscle : General features. Pelvis: Dissection : Pelvic viscera. heart. Lower Limb: Dissection: Gluteal region. 4. forearm.Nervous tissue : Structural characteristics of a neuron. 5. Prosected Parts: Sole of the foot and joints 6. detailed structure of : skeletal muscle. myelin and myelination. neuromuscular junction. structural features of compact and cancellous bone. Neuroglia : types. mediastinum. innvervation of skeletal muscle. 3.

References: A. Saunders Elsevier. Snell (2000) Little. 2. Atlas of Histology with functional correlation. cranial cavity. 2006 B. Histology 1.S. (The first or second editions may also be used). 2002. 36 . 15th edition (1996) • The following atlas is recommended for use in the Lab: 4. Cunningham’s Manual of Practical Anatomy G.I. II & III Oxford University Press. Submandibular region temporal and infratemporal fossa. Histology – Routine and special stained slides of all the tissues and organs of body. naso and oropharyngeal regions. orbit and eye ball. 2007.L. 2. Di Fiore’s International Edition 9th (2000). 3rd ed. Philadelphia. Lippincott Williams & Wilkins. Clinical Anatomy for Medical Student. Baltimore. Textbook of Human Histology (4th Edition) Inderbir Singh Jaypee Brother. Atlas of Human Anatomy. 6th Edition R. Netter FH.Romanes Vols. 3. Anatomy 1. Brown & Co. 4th ed. and neck. Moore KL & Agur AMR.

upon which an understanding of consequences in disease states can be built. Skills . Pharmaceutical Physiology Course Code: 1804251 Credit Hours: 4+2=6 Academic Level: Second Year Objectives: Knowledge . Explain the normal functioning of all the organ systems of the body and their interactions. Elucidate the physiological aspects of normal growth and development. Distinguish between normal and abnormal data derived as a result of tests which he/she has performed and observed in the laboratory. muscle. 5. Describe the physiological response and adaptations to environmental stresses. Description: Physiology is the study of functions and mechanisms of living organisms.At the end of the course the student will be able to: 1. Human Physiology is a course that addresses the processes and mechanisms that are characteristic of human life with an emphasis on several important systems and how these systems interact with each other for maintenance of homeostasis of the organism as a whole. 3. The objectives of this course are to provide students with fundamental concepts of how normal systems work. Perform experiments designed either primarily for the study of physiological phenomena or for assessment of function. The material will be presented under several major topic areas: general physiology and biological molecules. 2. cardiovascular. renal and neuro- physiology.At the end of the course the student will be able to: 1. endocrine. Analyze and interpret experimental/investigative data critically. 1. 4. Narrate the contribution of each organ system to the maintenance of homeostasis. respiratory. gastrointestinal. 2. These units will be integrated as the course progresses. 37 . List the physiological principles underlying pathogenesis and treatment of disease.

regulation of ANS activity Efferent pathway of ANS Sympathetic nervous system Parasympathetic nervous system Neurotransmitters: synthesis. Contents: Introduction. -ve feedback Plasma Membrane structure and function Membrane transport: Passive diffusion. reflexes Physiology of Pain Autonomic Nervous System: Introduction. function. An attempt will be made to emphasize understanding the fundamental processes and on problem solving rather than on memorization and recalling excessive amounts of ‘facts’. Muscle Mechanics Smooth Muscles: structure and mechanism of contraction Factors influencing contractility. osmosis and mediated transport Electrical signaling: Action potential Graded Action potential. Brain stem. Levels of CNS function The brain: Cerebral cortex. The study of intrinsic and extrinsic control systems and how they help maintain homeostasis is of prime importance in physiology. Cerebellum Blood Brain Barrier. Basal ganglia. conduction of Action potential Synaptic transmission: chemical synapses Factors affecting synaptic transmission Nervous system: Classes of neurons. Thalamus The brain: Hypothalamus. Length tension relationship Revision Cardiac Physiology: Functional anatomy of the heart Electrical activity of the heart 38 . function and termination of activity Functions of ANS Adrenal Medulla Skeletal muscles: structure Skeletal muscles: Neuromuscular junction and transmission Mechanism of contraction Types of muscle fibers. Cerebrospinal fluid Spinal cord: Composition. homeostasis.

and (c) Temperature 3. blood typing and Rh Leukocytes. Recording and analysis of 12 lead ECG and to measure the mean electrical axis of heart. (b) Arterial occlusion. Pituitary gland and Hypothalamus relationship -ve feedback control of hormone release Pituitary. ECG Cardiac cycle Cardiac Output: Control of Heart rate Control of Stroke Volume Circulatory system: Blood vessels. 2. Erythrocytes. and homeostasis Physiology of respiration and ventilation Respiration Mechanics. blood flow Regulation of ABP. Platelets. 39 . Regulation Pulmonary function tests Blood Gases Physiology of digestion Regulation of GIT functions Stomach and Gastric secretions Liver Physiology Renal Physiology: Nephron Glomerular filtration Tubular reabsorption Fluid and acid base balance Hormones: Biochemical classification. Capillary exchange Blood: Plasma. vasoactive substances Venous return. Functional classification Mechanism of action of hormones. ANS. blood pressure. Thyroid and Parathyroid hormones Adrenal and Pancreatic hormones Practical: 1. Measurement of blood flow in the forearm by venous occlusion plethysmography and to demonstrate the effect of (a) Exercise. Study of the factors controlling inotropic and chronotropic functions in isolated perfused frog’s heart.

Blakiston's Son & Co. The dosage of the oxygen and carbon dioxide in the expired and alveolar air (Orsat’s device).Original from Stanford University. 40 . 4. The physical properties of urine. Determination of strength-duration curve in frog’s nerve and muscle 10. clotting time and plasma prothrombin time 8. Determination of ABO and Rh blood groups 7. Being a Manual for the Physiological Laboratory. Urea and creatinine clearance 13. Determination of bleeding time. Published 1895 P. Determination of total red blood cell count 5. Determination of total leucocyte count 6. (ii) neurotransmitters. The investigation of the renal function. ions. 2006. and (iii) cold in vitro 12. Demonstration of compound action potential in a frog’s sciatic nerve 9. The test of urine dilution and concentration. Respiratory gases. References: Outlines of Practical Physiology. Study of the movements of isolated segment of mammalian small intestine and the effects of: 11. Digitized Mar 3. Arterial blood pressure testing. By William Stirling.

Classification and Features 15. etc. Necrosis. Infectious Diseases-General 19. First Semester Objectives: This course is designed to provide an overview of most aspects of general pathology. Tissue Healing & Review 10. Pathology of Nutritional Deficiencies 26. Contents: 1. Hypersensitivity and Immunology 14. infectious diseases. Cell Function and Adaptation 2. inflammation and repair. Hematopoiesis and Hemostasis 5. Causes & Results of Flow Disturbances 22. Pathology of Nutritional Excesses 25. Histocompatibility Complex & Cytokines 12. This course is designed to explain the mechanisms of disease processes. Tissue Transplantation & Immunodeficiencies 13. Acute Inflammation 6. Molecular Pathology II 18. Infectious Diseases-Bacteria. Environmental Pathology References: Basic Pathology. Fungi. molecular pathology. Apoptosis & Cellular Accumulations 3. The topics include abnormal cell function. 2003. disturbances of flow and nutritional pathology. hematology. and genetics. Pathology Course Code: 1804352 Credit Hours: 2+1=3 Academic Level: Third Year. by Vinay Kumar et al. At first glance many topics appear distinct and unrelated. Course Intro. immunology. Hematopoiesis and Hemostasis 4. CV Diseases Associated with Obstruction of Blood Flow 23. 7th edition. Mediators of Inflammation 8. 20. nutrition (cholesterol and fat). Mechanisms of Inflammatory Tissue Injury 9.. Immune System Cells & Functions 11. Neoplasia. flow. Disease Associated with Flow Disturbance of Other Fluids 24. Molecular Pathology I 17. 41 . Chronic Inflammation 7. but you should become aware of their interrelationships during the course. genetics. Infectious Diseases-Virology 21. An example is the pathology of coronary heart disease that includes the topics of inflammation. Injury. vital background for understanding the actions of drugs. Mechanisms of Neoplasia 16.

Outline the basic concepts of hypothesis testing. and some procedures for hypothesis testing. Define and determine the various measures of central tendency. Describe the basic concepts and some methods of the tabular presentation of data. so that the student understands their relevance to the biomedical research. measures of dispersion. Objectives: The student will be able to: 1. Definition and types of biostatistics 2. Describe the basic concepts and some methods of the graphical presentation of data. Measures of dispersion 10. Practical application of Analytic Biostatistics using the “SPSS”. Way of usage of the “SPSS” 42 . Population and samples 4. Contents: Lectures: 1. Definition and types of variables 3. Measures of central tendency 9. Description and summarization of data 5. 7. emphasis will also be paid to some important practical application of biostatistics using the SPSS. 14. 13. 3. Describe the meaning and uses of hypothesis testing of arithmetic means. Introduction to the program “SPSS” 2. Define normal distribution and describe the characteristics. Define a variable and identify different types of variables. Emphasis will be paid to some important topics such as the meaning and use of frequency distribution. 2. Describe the meaning and uses of hypothesis testing of proportion. 10. Tabular presentation of data 7. Define population and sample. Graphical presentation of data 8. measures of location. Define biostatistics and its types. 12. 8. 9. Biostatistics Course Code: 1801447 Credit Hours: 2+1=3 Academic Level: Fifth year. Hypothesis testing 12. Tests of significance for continuous data 13. Tests of significance for categorical data Practical 1. 11. 4. Usage of the statistical program “SPSS”. Moreover. Normal distribution curve 11. and identify some types of samples. Practical application of Descriptive Biostatistics using the “SPSS”. Define and determine the various measures of dispersion. second semester Description: The course introduces the student to the general description and understanding of some aspects of BASIC BIOSTATISTICS including basic concepts in presentation of raw data and different methods of data analysis. 6. Frequency distribution 6. 5.

Entry the raw data into the “SPSS” 4. GENERAL BIOSTATISTICS. F. 2. Practical application of Descriptive Biostatistics at the “SPSS” 8. W. Chase & F. BIOSTATISTICS: A Foundation for Analysis in Health Sciences. W. 43 . 3. Daniel. Bown. Change part of the raw data and resave at the “SPSS” 7. Recall the raw data using the “SPSS” 6. L. All other textbooks covering the course content. BIOSTATISTICS: The Bare Essentials. Norman & D. Strainer. 4. 3. Practical application of Analytic Biostatistics at the SPSS” References: 1. W. Save the raw data into the “SPSS” 5. G.

Second Semester Objectives: At the end of your undergraduate teaching you will be expected to be able to: 1. Be familiar with the practice of the genetic counseling clinic. 44 . genotype- phenotype correlation. 5. Learned approaches which can be used for the diagnosis of genetic disease and carrier detection. Chromosome abnormalities: Numerical abnormalities. 7. functional effects of mutations on the protein. Extragenic DNA. Mosaicism and chimerism (Mixoploidy). Chromosome structure. The genetic code: Triplet codons. DNA repair. Learned different forms of DNA testing: prenatal diagnosis. 4. Be familiar with the major ethical issues. structure. Be able to write a DNA report and chromosome report. DNA: the hereditary material composition. Post-Translational Modification. Know when and where to get genetic advice and information. 2. Lecture 5-7: Mutations: Types of mutation. transcriptional factors. Transcription: Post-Transcriptional processing. Mitochondrial DNA. RNA-directed DNA synthesis. classification. Medical Genetics Course Code: 1803332 Credit Hours: 2+1=3 Academic Level: Third Year. Contents: I. structural abnormalities. Have knowledge of several Mendelian and chromosomal conditions. 8. the sex chromosomes. Mutagens and mutagenesis: Mutagens. 6. • LECTURES 8-15 CHROMOSOMES AND CELL DIVISION: LECTURES 8-15: Human chromosomes: morphology. Regulation of gene expression: control of transcription. post-transcriptional control of gene expression. Cell division: Mitosis. predictive testing. the cell cycle. 3. Principles of Human Genetics: fifteen lectures • LECTURES 1-6: THE CELLULAR AND MOLECULAR BASIS OF INHERITANCE: Lecture 1: The cell. Lecture 2-4: Types of DNA sequences: Nuclear genes. Recognise patterns of inheritance. Translation: transfer RNA. spermatogenesis. 9. Gametogenesis: Oogenesis. structural effects of mutations on the protein. replication. and diagnostic testing. Recognise the genetic and environmental contribution to multifactorial conditions. meiosis.

disease associations. animal studies. Lecture 8: Applications of the techniques of DNA analysis: analysis of gene structure. diagnosis in non-genetic disease. autosomal recessive inheritance. Diabetes mellitus. biochemical factors. genomic imprinting. identification of oncogenes function of oncogenes. newborn infants. type of oncogenes. Oncogenes: relationship between C-ONC and V-ONC. Nucleic acid hybridization. Molecular cytogenetics: Fluorescent in situ hybridization (FISH). Non-Mendelian inheritance: Anticipation. restriction mapping. • LECTURE 13: GENETIC FACTORS IN COMMON DISEASES: Genetic susceptibility to common disease: types and mechanisms of genetic susceptibility. twin studies. • LECTURE 9-10: PATTERNS OF INHERITANCE: Family studies: Pedigree drawing and terminology. Prostate cancer. congenital abnormalities and perinatal mortality. Mendelian inheritance: autosomal dominant inheritance. chromosome banding. mitochondrial inheritance. Lecture 3-4: Principles of DNA technology: DNA cloning. Molecular pathology. establishing the mode of inheritance of a genetic disorder. Genetics of common cancers: Colorectal cancer. mutation screening techniques. Molecular Diagnostic of inherited disease: • LECTURE 1-8: DNA TECHNOLOGY AND APPLICATIONS: Lecture 1-2: Methods of chromosome analysis: Chromosome preparation. Karyotype analysis. uniparental disomy. and viral studies. p53. coronary heart disease. Alzheimer’s disease. Lecture 5-7: Techniques of DNA analysis: Nucleic acid probes. approaches to demonstrate genetic susceptibility to common diseases. inherited susceptibility for the common cancers Screening for familial cancer. • LECTURE 11-12: THE GENETIC OF CANCER: Differentiating between genetic and environmental factors in cancer: epidemiological studies. mutational analysis of single gene disorders. hypertension. • LECTURE 14: GENETICS AND CONGENITAL ABNORMALITIES: Incidence: Spontaneous first-trimester pregnancy loss. Ovarian cancer. family studies. Comparative genomic hybridization (CGH). Tumour suppressor genes: Retinoblastoma. childhood 45 . DNA sequencing. flow cytometry.II. Mosaicism. six-linked inheritance. Genetic counseling in familial cancer: inherited cancer=predisposing syndromes. Chromosome nomenclature. Breast Cancer. multiple alleles. schizophrenia.

Haemophilia. • LECTURE 15-16: CHROMOSOME DISORDERS: Incidence of chromosome abnormalities. The use of linked markers. Indications for chromosome analysis. Environmental agents (teratogens): drugs and chemicals. maternal infections. Hereditary motor and sensory neuropathy. Empiric risks. Prenatal treatment. Disorders of steroid metabolism. • LECTURE 20: CARRIER DETECTION AND PRESYMPTOMATIC DIAGNOSIS: Carrier testing for autosomal recessive and X-linked disorders. Molecular pathology. diagnosis in non-genetic disease. Autosomal dominant inheritance. Evolutionary origin of variation in drug responses. • LECTURE 21: RISK CALCULATION: Probability theory. Human prion diseases. Indications for prenatal diagnosis. Disorders of sexual differentiation. Disorders of carbohydrate metabolism. Disorders of purine/pyrimidine metabolism. Hereditary disorders with altered drug response. Spinal muscular atrophy. physical agents. • LECTURE 22: DNA DIAGNOSIS Mutational analysis of single gene disorders. Termination of pregnancy. Genetic variations revealed solely by the effects of drugs. Presymptomatic diagnosis of autosomal dominant disorders. • LECTURE 19: BIOCHEMICAL GENETICS: The inborn errors of metabolism. Bayes theorem prenatal screening. • LECTURE 23: PRENATAL DIAGNOSIS OF GENETIC DISEASE: Techniques used in prenatal diagnosis. Myotonic dystrophy. Genetic causes of malformations: Chromosome abnormalities. maternal illness. Ethical considerations in carrier detection and predictive testing. • LECTURE 24: POPULATION SCREENING AND COMMUNITY GENETICS: 46 . Disorders of branched chain amino acid metabolism. Disorders of prophyrin metabolism. Disorders of the autosomes. Lysosomal storage disorders. Disorders of amino acid metabolism. and genetic heterogeneity. Urea cycle disorders. New prenatal diagnosis techniques under development. Chromosome breakage syndromes. multiple abnormalities. single gene defects. special problems in prenatal diagnosis. Drug metabolism. Huntington’s disease. Neurofibromatosis. Sex-linked recessive inheritance. Duchenne muscular dystrophy. Disorders of the sex chromosomes. Disorders of lipid metabolism. Autosomal recessive inheritance. multifactorial inheritance. Diagnosis of multiple gene disorders. • LECTURE 17: SINGLE GENE DISORDERS: Sickle cell anemia.mortality. Definitions and classification of birth defects: single abnormalities. Organic acid disorders prenatal diagnosis of the inborn errors of metabolism. Cystic fibrosis. • LECTURE 18: PHARMACOGENETICS: Definition. Malformations of unknown cause.

• PRACTICAL 14: Visiting DNA diagnostic Labs in our faculty to demonstrate for the students the advanced instrument that can be used for DNA diagnosis of inherited diseases. genetic counseling-directive or non-directive. chromosomal banding (G banding. centromeric banding): students will introduced to learning different types of chromosomal staining and how they can use it in identifying chromosome and chromosomal abnormalities. establishing the diagnosis. References: Emery's Elements of Medical Genetics. Prenatal screening. discussing the options. • PRACTICAL 6-9: DNA Cloning: students will learn different techniques fro DNA cloning and its usefulness in identifying the gene sequence. by Mueller RF and Young ID. treatment of genetic disease. gene therapy. special problems in genetic counseling. • PRACTICAL 10: Molecular diagnosis of inherited diseases: after the students become familiar with different molecular diagnostic techniques they will start to learn how they can use this method in diagnosis of different inherited diseases. Genetic registers. communication and support. The human genome project. gel electrophoresis. Neonatal screening. and risk calculation. • PRACTICAL 11-13: Human cytogenetics: chromosomal preparation. Criteria for a screening program. reverse. outcomes in genetic counseling. Practical: • PRACTICAL 1-5: Genotypes & Phenotypes: in these practical students will learn: PCR technique. 11th edition 47 . Quinacrine. TREATMENT OF GENETIC DISEASE AND GENE THERAPY: Definition. THE HUMAN GENOME PROJECT. calculating and presenting the risk. population carrier screening. RFLPs analysis. • LECTURE 25: GENETIC COUNSELLING.

Medical Professions and its Behaviors Course Code: 1000111 Credit Hours: 2 Academic Level: First Year Objectives: 1) General Objectives: This course aims at preparing students of medicine and medical sciences to understand the behavior of the medical profession which comes from Islamic principles and values. § The difference between the law and behavior of practicing medical professions. To identify the group work in the medical team. . and the basic medical behaviors in Islam. To identify the Islamic history in medical care. . To identify rights and duties for the patient and his family. . and who have direct or indirect relationship with the patient or their families. . To identify the basic behaviors for the scientific research in the medical field. Lecture no 3 : Characteristic of the profession’s behavior in Islam. . technicians and nurses. and society during practicing medical professions. § An introduction to the history of medicine and the morality of the profession among Muslims. Lecture no. To identify the Islamic guidelines and the basic knowledge from which we get the profession behavior and attitude in the medical field. 2) Specific Objectives: . 48 . and profession practice behavior in Islam. § Identifying profession mistakes. § Identifying the different medical organizations. Contents: Lecture no 1 : An introduction to the medical professions course and its moral behavior. To identify behaviors and attitudes of learning. and learning control on the patient during and after the study. § Presenting the course objectives and the contents of the course. in order to guide their practice to achieve the best level of medical care for those who are involved in the medical field as doctors. . 2 : System and behavior of the medical professions: § Identifying the medical section and its part. § Different medical professions. specialists. To identify the characteristic of the muslim doctor.

§ Treatment and its rules.
§ Islamic rules in profession practice.
§ Rules of death and death struggle.

Lecture no. 4 : Characteristic of the profession’s behavior in Islam.
§ Origins of muslim doctor’s knowledge.
§ The nature of the Muslim doctor.
§ Rule of payments in the medical field.

Lecture no. 5 : Rules of some of the patient’s worshipment:
§ Rules of the patient’s cleanness.
§ Rules of the patient’s prayers.
§ Rules of the patient’s fasting.
§ Other rules has to be known by the patient’s relatives.

Lecture no. 6 : Practical application (1) – Group work:
§ Students are divided into small groups under the supervision of
one of the teachers to discuss different matters which relate to
what they had taken in the first half of the class.
§ A representative of each group presents his group’s topic and
their opinions.
§ Every teacher evaluate student’s participation in his group.

Lecture no. 7 : Behavior and moralities of the profession in learning.
§ Continuous learning in a particular major during practicing.
§ General behavior in learning and in dealing with practitioners,
teachers, technicians, and others.
§ Behavior of dealing with equals.
§ Preserving opinion rights.
§ Fighting cheating.

Lecture no. 8 : Patient’s rights and duties (1):
§ His right in taking or rejecting the medicine.
§ His right in good treatment.
§ His right in preserving his secrets and in covering his private
parts.
§ His right in telling his true information concerning his disease,
the results of the medical test, the plan for his treatment, the
side
§ effects, and the dangers he probably go through, in order to
take the appropriate decisions.

Lecture no. 9 : Patient’s rights and duties (2):
§ Taking care of the rights and circumstances for the old patients,
children and special need patients.
§ Patient’s duty towards medical practitioners and the medical
organizations: truthfulness in giving information to the medical
team, necessity of appointments and implementing medicine
instructions, diet and taking medicine.
49

Lecture no. 10 : Medical practitioner rights:
§ Their rights on the single, the society and the medical
organization which they belong to trust them, respect them and
protect them and preserve their rights and dignities.
§ Provide them with an appropriate culture.
§ Provide them with all requirements to practice their
professions.

Lecture no. 11 :Duties of medical profession’s practitioners:
§ To watch Allah in secret and in Public.
§ To preserve all patient’s rights.
§ Not to differentiate between patients.
§ To work with a Muslim doctor behavior which shows honesty
and truthfulness.
§ To respect members of the medical team.
§ To teach and evaluate students under his supervision with
honesty and truthfulness.
§ To be good examples in their manners.

Lecture no. 12 :Practical applications (2) – Group work:
§ Students are divided into small groups under the supervision of
on of the teacher to discuss different matters which relate to
what they had taken in the first half of the class.
§ A retrospective of each group represents his group’s topic and
their opinions.
§ Every teacher evaluates student’s participation in his group.

Lecture 13 :Rights and duties of the society:
§ To take care of the single’s heath, the society, and the culture
by medical advisement and protectoral program.
§ To work on improving the standards of medical services.
§ To follow updated matters in particular majors, to improve the
level of implementation.
§ Honesty and truthfulness in exchanging information and in
giving reports and certificates.
§ To write the correct and complete information in the medical
file.
§ To prepare the medical organization with all needed systems,
preparation and employees.

Lecture no. 14 :Attitudes of learning on the patient:
§ The necessity of learning on the patient during and after the
study.
§ Control of learning on the patient.
§ To preserve the patients rights and ask him permission or
whose in charge.
§ Control of confirming, registering and describing the patient’s
case.

50

Lecture no. 15 :Attitude of researches in the medical field.
§ Controls of researches and experiments on animals.
§ Controls of researches and experiments on human being.
§ To persevere thoughtful ownership for its owners.

References: § Ibn Al-Qayyem, ‫اﻟﻄﺐ اﻟﻨﺒﻮي‬
§ Dr. Muhammad Ali- Al-Bar, ‫اﻟﻤﺴﺌﻮﻟﯿﺔ اﻟﻄﺒﯿﺔ‬
§ Dr. Ahmed Sharaf Al-Abedeen, ‫اﻻﺣﻜﺎم اﻟﺸﺮﻋﯿﺔ ﻟﻼﻋﻤﺎل اﻟﻄﯿﺒﺔ‬
§ Dr. Wajeeh Zain-Al-Abedeen, ‫اﻟﻄﺒﯿﺐ اﻟﻤﺴﻠﻢ‬
§ Dr. Ziyad Darweesh, ‫أداب اﻟﻄﺐ‬
§ Dr. Abdullah M. Al-Abd, ‫ ﻟﻠﺮازي‬-‫اﺧﻼق اﻟﻄﯿﯿﺐ‬
§ Dr. Ali Al-Defa’a, ‫ﻟﻤﺤﺎت ﻣﻦ ﺗﺎرﯾﺦ اﻟﻄﺐ ﻋﻨﺪ اﻟﻤﺴﻠﻤﯿﻦ اﻻواﺋﻞ‬
§ ‫ﻧﻈﺎم ﻣﺰاوﻟﺔ اﻟﻤﮭﻦ اﻟﺼﺤﺔ ﻓﻲ اﻟﻤﻤﻠﻜﺔ اﻟﻌﺮﺑﯿﺔ اﻟﺴﻌﻮدﯾﺔ‬
§ ‫ﻣﺠﻠﺔ اﻟﺒﺤﻮت اﻟﻔﻘﮭﯿﺔ اﻟﻤﻌﺎﺻﺮة‬
§ Dr. Merizen S. Assiry, ‫ﻻﺳﺤﺎق ﺑﻦ ﻋﻠﻲ اﻟﺮھﺎوي‬- ‫اداب اﻟﻄﺒﯿﺐ‬
§ Dr. Abdul Rahman H. Al-Nafeesa ‫ﻣﺬﻛﺮة ﻣﺴﺌﻮﻟﯿﺔ اﻷﻃﺒﺎء‬
§ The committee of Muslim doctor, ‫ﺳﻠﺴﻠﺔ اﻟﻔﺘﺎوي اﻟﻔﻘﮭﯿﺔ اﻟﻄﺒﯿﺔ اﻟﻌﺎﻣﺔ‬
§ Dr. Al-Ahmed Abu Al-Noor, ‫ﺣﻘﻮق و واﺟﺒﺎت اﻟﻄﺒﯿﺐ‬
§ ‫ﻣﺠﻠﺔ اﻟﺒﺤﻮث اﻻﺳﻼﻣﯿﺔ‬
§ ‫ﻧﺸﺮات اﻟﻤﻨﻈﻤﺔ اﻻﺳﻼﻣﯿﺔ ﻟﻠﻌﻠﻮم اﻟﻄﺒﯿﮫ‬
§ Articles for Dr. H. Hathoot in gynecology in Islam.
§ Islamic perspective in Obstetric & Gynaecology. Hassan
Hathout.
Principles of Medical Ethics. In current Options.
By: American Medical Association.
Prepared by the Council on Ethical and Judicial Affairs.
Chicago, AMA, a989, P ix.
§ Kennedy Institute of Ethics.
§ Bioetheics line, National Liberary of Medicine, Washington
DC.
§ Encyclopedia of Bioethics 4 Vol., New York, Fee Press, 1978.

51

Umm Al-Qura University Faculty of Pharmacy Department of Pharmacology Modules 2008 52 .

It is not just “what effect does this extract have?”. 3. Describe possible factors which might increase hazards of drug administration or modify drug action e. It also aims to continue to introduce the students to some desirable independent learning habits and attitudes necessary to pursue further training in the Pharmacy practice. 5. Pharmacology is also concerned with the search for new drugs and how they can best be used in the treatment of diseases in both man and animals. impaired renal function. Course description and organization The course consists of 168 hours 140 lectures and 28 hours of practical classes. what is the active ingredient and how can we harness the therapeutic effect. uses and effects”. Understand the principles of drug action that is site and mechanism of action of drugs at the molecular as well as physiological levels and knowledge of the consequent effects on the different systems. distribution. It provides a study programme which aims to help students to acquire the basic knowledge and skills in pharmacology essential for the study of the mechanisms of action and use of drugs and links biochemistry. drug-drug interaction. but “how does it do it. B. predictable extension of inherent pharmacological properties. The course of clinical pharmacology is designed to train students on rational clinical thinking and to be able to integrate facts and concepts of basic pharmacology so as to solve clinical problems and allow them to be a part of the health team providers. drug dependence potential . 4. and the appropriate measures to counteract these toxicities.Major course objectives The General objectives of the programme are as follows: On completion of the course in Pharmacology the student will: In order to achieve adequate knowledge and competence in pharmacology which can later be used as a basis for rational drug therapy in pharmacy practice the student shall: 1. Allergic (immunologic) reaction. their preparation. Be aware of the different mechanisms of drug toxicity. The course of practical pharmacology is designed to supplement and enforce the basic knowledge of how drugs act and introduce the students to the methods and tools used by pharmacist to acquire new information about existing drugs or how to find new ones. metabolism and excretion. pathology and infections diseases with an understanding of disease at the molecular level. . namely overdose. Understand the principles of drug absorption. impaired hepatic function. both desirable and adverse. pregnancy. Recognize that drugs that have action on all systems and he shall be able to group 53 . physiology. history of drug sensitivity. Course overview A.etc. Appreciate the possible interactions of drugs with other drug as well as with diet. pharmacogenetic reaction. bioavailability. 2. Also he should be able to apply the pharmacokinetic principles in therapeutic practice. Pharmacology Pharmacology is defined as “that branch of medical science which relates to drugs. 6. C. morphology.. co-existent disease states. age and weight.g. Introduction to the syllabus The syllabus is a guide to the course of Pharmacology for the 3rd and 4th year.

Dale M. explain and clarify difficult points. together those drugs with common pharmacological properties and at the same time appreciate that drug classification are for convenience and not absolute. transparencies and films will be used frequently during lectures and discussions to facilitate learning. Lectures This form of instruction is used to deliver factual knowledge.P. a. b. Rang H. Know the underlying principle and pathophysiology of disease and basic facts of pharmacology and pharmacotherapy which must be interdigitated in order to select drugs and establish therapeutic objectives. Ed. 7. Seminars and Conferences: Selected topics may be chosen for further study and students or student groups assigned to present and discuss them. To equip himself with a comprehensive description of drug or group of drugs as applied to the practice of medicine so that he is sufficiently trained to acquire information on other therapeutic agents by self instruction. or to informally test the level of learning of the students by selective questions and problems. 8. Video recorded case presentation as well as experimental demonstration on video tapes are used in selected parts of the syllabus where possible. Churchill Livingstone. Know the common or serious side effects and contraindications of each prototype drug especially those which can be deduced from its pharmacological properties. Pergamon Press. 2. Goodman and Gilman´s The Pharmacological Basis of Therapeutics. Be able to know one or two prototype drugs of each pharmacological group. Teaching materials and resources Audiovisual aids including video tapes. These periods can be used to review covered material and further clarify lecture or reading assignments. practical classes. pose pertinent questions and directs students to the more salient points. 10. Katzung : Basic and Clinical Pharmacology. Prentice Hall.. D.Required texts and resources The main textbooks are: 1. c. Other readings: 54 . 11. 9. Alfred Goodman Gilman. particularly those of clinical importance and know the site and mechanism of each prototype drug.: Pharmacology. The approach adopted in teaching the course of basic and pharmacology is to place a premium on comprehensive understanding and to reduce the role of memorization to minimum.M. B. slides. Teaching methods Teaching methods used in the courses include lectures. F. the general principles involved in the management of acute drug poisoning by some drugs as well as basic knowledge about adverse interactions. Ed. 3. Practical Classes: The laboratory course is designed to supplement the lecture course and run in parallel with it. Know at this early stage. E. Inc. seminars and assignments.

Lawrence . 3. 4. Clinical Pharmacology and Therapeutic d. The practical time is also advisably used for clarifying aspects of the topic with instructors. This in essence is an introduction to the scientific method. 5. Modern Pharmacology .R. P. C. Participate in discussions. Craig and R. Express themselves in scientific language. To develop in students the ability to observe. 2. and tutorial . J. To reinforce the theoretical knowledge gained by reading and attending lectures through selected laboratory experiments in various areas of pharmacology. 55 . Stitzel Little Brown and Co. 2. 4. of Clinical Pharmacology c. 5. 3. To prepare for practical classes students are urged to: 1. Learn the process of problem-solving. 3. Read their practical worksheets so as to familiarize themselves with the objective of the practical session and to look up terms new to them. Clinical Pharmacology D. do some measurements. Wherever necessary students should consult their textbooks on the theoretical aspects of the practical. Pharmacology and Experimental Therapeutics Practical The main purposes of the practical course are: 1. British J.In addition the following journals are recommended for special readings in Pharmacology: a. Seminars The seminars are used for developing the ability of students to: 1. Ask questions on points which require clarification. Pharmacology: b. British J. Students are expected to: 1. . 2. Integrate knowledge. Read seminars topics 2.N. A record of the practical should be kept according t the instructions. Prepare for discussing their knowledge. To familiarize students with some instruments and equipment used in clinical practice. Trends in Pharmacological Sciences e. collect data and draw conclusions based on his findings. Bennett Churchill Livingstone.4.Boston. and 3.E. seminars are also useful for receiving additional in depth information.R.

Get acquainted with the different sub-division of pharmacology. 2. Appreciate the importance of pharmacology in the practice of pharmacy 4. 3. Excretion of drugs 56 . Recognize that these parameters can be modified in certain disease states such hepatic. Contents: 1. Drug nomenclature 6. Basic principles (12 CU): 2. 2. Sources of drugs and development of new drugs 7. bioavailability. Pharmacology I Course Code: 1801341 Credit Hours: 3+1=4 Academic Level: Third Year. peak and minimum therapeutic concentration. Transport of drugs across body membranes 2. Sources of information about drugs 8. At the end of this course the student will. 3. first pass effect and extraction. renal or cardiac failure which necessitate dose adjustment to avoid drug toxicity. First Semester Objectives and Contents 1.1 Pharmacokinetics (2 CU): Objectives: 1. area under the curve. elimination constants the clearance. Classification of drugs and prototype drugs 9. 2. Be aware of the dose response curves and the pharmacokinetic parameters such as half-life. Sub-divisions of pharmacology 3. Drug biotransformation 5. volume of distribution. Absorption of drugs 3. Appreciate the clinical importance of applying the knowledge of these pharmacokinetic parameters in designing drug dose- regimens to achieve drug effectiveness and safety. Importance of pharmacology in the practice of pharmacy 4. Routs of drug administration 2. 5. Definition of drug and of pharmacology. Dosage forms of drugs 10. Be aware of some basic notions and definitions of pharmacology. Contents: 1. Know sources of drugs. understand that pharmacology is the study of mechanism of action and use of drugs in health and diseases. development of new drugs and be able to gather information about drugs. Drug distribution 4. Introduction and Definitions: (2 CU) Objectives: 1. Know the different nomenclatures of drugs. 6.

dose response curves 3. 4. Know the important variables which can influence drug action. Drug allergies 3. efficacy and antagonism 4. The four major classes of drug allergies 8. Drug interactions and its results (synergism) 6. Medication errors and compliance 5.4 Unwanted effects of drugs (2 CU): Objectives: 1. Variation in drug responsiveness 2. The concept of over extension of the pharmacological response 6. Be acquainted with the mechanisms involved and important examples in each case. spare receptor. Understand the concept of receptors and their importance for explaining drug actions. 3. signaling mechanisms. 2. 3. Be acquainted with the concept of individualization of drug therapy. Be aware of the dosage of drugs in relation to age and weight and the special formulas for calculation of dose for children. coupling protein. Be aware of the graded dose-response curve. Quantitative aspects of drug potency. Organ directed toxicity 7. Biological variation 2. Benefit to Risk Ratio 5. 3. Contents: 1. therapeutic index. Be aware of the fact that all drugs are toxic to individuals if large enough doses have toxic effects which often occur after therapeutic doses. Drug idiosyncratic responses 57 . 2. 4. coupling proteins 2. Kinetic processes and the calculations with appropriate formulas 2. Contents: 1. Bioavailability and bioequivalence of drug products 7. 6. Be able to recognize such adverse effects of drugs and how to prevent or minimize such unwanted effects. Concept of receptors. 2. Special formulas for calculating dosage for children. Receptor theory. Dose dependent toxicity 2.3 Factors affecting drug response (3 CU): Objectives: 1. Body weight and volume of distribution 3. signaling mechanisms. Be aware of the general phenomenon of biological variation. efficacy and drug antagonism Contents: 1. Acquire knowledge on quantitative aspects of drug potency. Age and sex. agonist. effector mechanisms receptor agonist.2 Pharmacodynamics (5 CU): Objectives: 1. partial agonists. Pharmacokinetic parameters and clinical applications 8. Drug idiosyncrasies 4. Pharamacognetics 2.

Pharmacological Modification of Autonomic Function 3. Describe the pharmacological action and indication 3. Adverse Effects D. Describe the action of several toxins that affect nerve function.4 Ganglion blocking agents: (1 CU): Objectives: 1. Contents: 1. Contraindications 4. Indirect-acting Cholinomimetics 3. 5. 2. Recognize the adverse effects and contraindications of this group of drug Contents: 1. 58 . 2. Functional Organization of Autonomic Activity 5. Adverse effects D. List the major types of receptors found on autonomic effector tissues. Describe the organ system effects of stimulation of the parasympathetic and sympathetic systems. 3. Neurotransmitter Chemistry of the Autonomic Nervous System 3. Predict the inhibitors of the function of the major organ systems. Introduction 2.3 Antagonists at muscarinic receptor sites: (2 CU): Objectives: 1. 3. Direct-Acting Cholinomimetics A. Mode of Action of Cholinomimetic Drugs 3. Basic Pharmacology B. Recognize the autonomic sites at which acetylcholine acts as a chemical transmitter. Basic Pharmacology B. List the antimuscarinic drugs used in clinical practice 2.2 Cholinergic drugs: (2 CU) Objectives: 1. Describe the steps in the synthesis and the termination of action of the major autonomic transmitters. Know the synthesis and enzymatic degrade acetylcholine and recognize the physiologic of the released transmitter.3. Know prototype ganglion blockers and their mechanism of action.1 Introduction to pharmacology of the autonomic nervous system: (2 CU): Objectives: 1. Spectrum of Action of Cholinomimetics Drugs 2. Contents: 1. Autonomic Receptors 4. Muscarinic Receptor Antagonists A. Contraindications 3. Be aware of the pharmacology of cholinergic drugs (direct and indirect). 4. Clinical Pharmacology C. Clinical Uses C. Autonomic nervous system: (14 CU): 3.

neuromuscular junction 4.7 Adrenoceptor blocking agents:(3 CU): Objectives: 1. the classification of adrenoceptors (alpha1. 7. 3. Therapeutic use of beta-adrenoceptor agonists 8. Mechanism of Action 4. beta1. Adverse effects of alpha-adrenoceptor agonists. Know the pharmacological actions of these drugs and appreciate their limited use due to their specific actions Contents: 1. therapeutic uses and potential hazards involved in the use of these drugs and other related sympathomimetic agents Contents: 1. Pharmacology of Nicotin 3. Clinical Pharmacology of Neuromuscular Blocking Agents 5. Uses 5. Other Uses of Neuromuscular Blockers 6. Autonomic ganglia vs. molecular consequences of their activation. alpha2. parasympathetic nervous systems 2. 3. 9. Nicotinic vs. Differentiate between centrally and peripherally acting muscle relaxants 2. Be aware of the pharmacology of the group of drugs 3. 3. Gain insight about types.6 Adrenoceptor . Acquire knowledge of the basic pharmacological actions 59 . 6. Appreciate the concept of selective adrenoceptor blocking agents. Basic Pharmacology of Neuromuscular Blocking Drugs 3. 2. Introduction 2. Know the biosynthesis and metabolism of adrenaline. the pharmacologic effects of the sympathomimetics.activating drugs (3 CU): Objectives: 1. norepinephrine and the other catecholamines are removed from the biophase. Basic Pharmacology of Adrenoceptor Agonists 2. Spasmolytic Drugs 3. noradrenaline and dopamine 3. distribution and classification as well as the physiological function of the adrenergic receptors 2. The selectivity of ganglion-blocking drugs for sympathetic vs. Recognize the pharmacological actions. Adverse effects of alpha-adrenoceptor agonists. muscarinic receptors 3. . 2. Therapeutic use of alpha-adrenoceptor agonists. Clinical Pharmacology of Adrenoceptor Agonists 5. beta2 and D1). and their important locations. Recognize their clinical use and hazards Contents: 1.5 Antagonists at nicotinic receptor sites in the skeletal neuromuscular junction (1 CU): Objectives: 1. Therapeutic uses of dopamine. 4.

3. Recognize the main classes of prostaglandins and the basis of this classification 2.1 Histamine and antihistamines: (2 CU): Objectives: 1. 2. 4. The basic pharmacology of H1-receptor antagonists 3. Recognize the pharmacological effects of histamine on various histamine receptors 2. Contents: 1. Describe the pharmacological effects and therapeutic potentials of each class 3. Basic and Clinical Pharmacology of alpha-Adrenoceptor Antagonists 3.2 Serotonin (5-hydroxytryptamine) and antagonists (2 CU): Objectives: 1. 2.3 Prostaglandins and other Eicosanoids: (1 CU): Objectives: 1. Basic and Clinical Pharmacology of the beta-Adrenoceptor Antagonists 5. 4. the availability of antagonists and potential place in therapeutics. List the names of some compounds which antagonize the effects of 5-HT and their therapeutic uses. Appreciate the grouping of the various substances under the heading of autacoids although of widely different structures and pharmacological action. Be able to outline the biosynthesis and metabolism of 5-HT. Recognize the drugs which inhibit the synthesis and actions of 60 . their role in the body. Adverse Effects of alpha and beta-Adrenoceptor Antagonists 6. Describe the pharmacological effects. including the newer "non-sedating" H1 receptor blockers 4. Clinical Pharmacology of Reserpine 4. including drug interactions. Histamine ant it pharmacology 2. side effects and toxicity and indications of H1 and H2 receptor antagonists Contents: 1. 3. The pharmacology of serotonin The clinical use of serotonin receptor agonists and antagonists 4. Know the drugs which can inhibit histamine release and the drugs which can antagonize the effects of released histamine 3. because they share in common a natural occurrence in the body. Autacoids: (6 CU): Objectives: 1. Contents: 1. their possible value as drugs. underlying the therapeutic indications of both alpha and beta adrenoceptor blockers. Know the significance of these group of autacoids. The clinical uses and toxicity of H2-receptor blockers. Describe the pharmacological effects of 5-HT on different organs and subclassification of different 5-HT receptors. The clinical uses and toxicity of H1-receptor blockers. Anticipate the precautions and the possible hazards of using these drugs.

prostaglandins
Contents: 1. Pharmacology of prostaglandins and leukotriens.
2. Synthesis and factors affecting it.
3. Drugs affecting the synthesis and receptors.
The main clinical uses of eicosanoids and inhibitors of eicosanoid
synthesis.
5. Adverse effects
4.4 Polypeptides(1 CU):
Objectives: 1. Know the natural source of ergot alkaloids and the clinical
conditions associated with ergot poisoning and uses.
2. Recognize the site of formation/ degradation and physiological role
of angiotensin and factors controlling the plasma renin activity
(PRA)/ atrial natriuretic factor/ kallikrein/ kininogen
3. Understand the possible usefulness of angiotensin antagonists
Contents: 1. Ergot Alkaloids
2. Angiotensin II
3. Kinins
4. Other Peptides
a. Vasopressin
b. Oxytocin
5. Drug acting on the respiratory tract: (4 CU):
Objectives: 1. Have an idea about the proper use and contraindications of the
most commonly used drugs in management of pulmonary diseases.
2. Appreciate that certain drugs can result or exacerbate certain
pulmonary diseases.
5.1 The Bronchodilators: (2 CU):
Objectives: 1. Be acquainted with the different groups of drugs used in both acute
and chronic Asthma
2. Be familiar with the methods of administration of these drugs
according to the Clinical indications
3. Recognize the side effects and the limitations of the different drugs
Contents: 1. Types of bronchodilators
2. Basic and clinical pharmacology of bronchodilators
3. The bases for selecting therapeutic agents in bronchial asthma,
depending on the severity and duration of the symptoms.
4. The approach to treatment of different grades of asthma.
5.1 Antitussives and expectorants: (2 CU):
Objectives: 1. By the end of this part the student will:
2. Understand the various mechanism by which antitussive drugs
suppress cough
3. Know when to use various antitussive drugs in clinical practice and
when to use expectorants instead
4. Appreciate the unwanted effects, toxicity and interactions of these
antitussive drugs with other drugs

61

Contents: 1. Mechanism of cough suppression
2. Cough suppression
3. Expectorants
4. Mucolytics
6. Renal pharmacology: (4 CU):
Objectives: 1. Understand the renal handling of sodium, water an< other
electrolytes
2. Know the classification of the different diuretic: according to their
major site of action
3. Appreciate the possible changes in plasma electrolytes and pH of
blood
4. Know the therapeutic uses, adverse effects of each class of the
diuretics
Contents: 1. Pharmacology of diuretics.
2. Know the Classification of Agents Acting on Renal Function
- Carbonic anhydrase inhibitors
- Loop agents
- Thiazides
- Potassium-sparing diuretics
Refrencess: 6. Rang H.P., Dale M.M.: Pharmacology. Ed. Churchill Livingstone,
7. B. Katzung : Basic and Clinical Pharmacology. Prentice Hall; Inc.
8. Goodman and Gilman´s The Pharmacological Basis of
Therapeutics, Ed. Alfred Goodman Gilman, Pergamon Press.

62

Pharmacology II
Course Code: 1801342
Credit Hours: 2 +1 = 3
Academic Level: Third Year, Second Semester.
7. Drugs acting on the Central Nervous System: (14 CU):
7.1 Introduction(1CU):
Objectives: 1. The brain has a multitude of functions and drugs affect these
functions either by non-specifically modifying neuronal functions
or by interfering with neurochemical transmission.
2. At the end of this series of lectures the student will:
3. Become aware of the relative inaccessibility of some brain areas
and the properties of drugs which control the crossing of blood
brain barrier.
4. Appreciate the difficulty of interpretation and understanding the
mechanisms of Drug action on the central nervous system
acknowledging that there are at least 20 transmitters in the brain,
each may be excitatory or inhibitory dependent on location.
5. Know the drug interaction with presynaptic receptors which then
modulate the release of transmitters is a more frequent explanation
of drug action in the brain than in the autonomic nervous system.
6. Be aware of the possible links between chemical transmission and
nervous and mental disease, thus explaining drug action in the CNS
on a rational basis.
Contents: CNS neurotransmitters and relations to different CNS diseases.
7.2 Anxiolytics, Sedatives and Hypnotics: (2 CU):
Objectives: 1. To understand the stages of central nervous system depression as
they pertain to the actions of these agents.
2. To understand the classification of central nervous system
depressants.
3. To understand the theories relating to the biochemical mechanism
of action of anxiolytics, sedatives and hypnotics, with particular
emphasis on the barbiturates and benzodiazepines.
4. To understand the effects of these agents on the cardiovascular,
respiratory and central nervous systems.
5. To know the advantages and disadvantages of each class relative to
the others.
6. To appreciate why new drugs are being developed in this area.
Contents: 1. Introduction and Definitions
2. Ethanol
3. Barbiturates
4. Benzodiazepines
5. Other Agents: the rationale, advantages and disadvantages
of the following as hypnotics or anxiolytics:
- chloral hydrates, paraldehyde
- zolpidem, zaleplon, eszopiclone, ramelteon
- antipsychotics, antidepressants, antihistamines
- beta-blockers
- buspirone
7.3 Antiepileptic drugs: (1CU):
Objectives 1. To understand the different types of seizures and the drug classes
63

Understand the underlying mechanism of parkinsonism and the relation between The cholinergic and dopaminergic mechanism in its etiology 2. To understand the proposed mechanisms of actions of antiepileptics.6 General anesthetics: (1 CU): Objectives: 1. Status Epilepticus. Contents: 1.4 Antiparkinsonian drugs(1 CU): Objectives: 1. for each class. and Partial Seizures 4. Mechanisms of Action 3. Miscellaneous agents).5 Antidepressants: (1 CU): Objectives: 1. most effective in their management. Micellaneous antidepressants 4. amantadine clorgylin. 7. To appreciate the pharmacological and clinical differences among the inhalational anesthetics and between these agents and fixed 64 . synthetic anticholinergic agents. Know the adverse effects. mild and severe. 3. Tricyclic antidepressants (TCA's) 2. Monoamine oxidase inhibitors (MAO-I's) 3. 2. L-dopa plus peripheral decarboxylase inhibitors bromocriptine. To understand the characteristics which determine the potency of general anesthetics and rate of induction. Understand the pharmacological data that implicate neurotransmitter abnormalities as associated with/causal of the mood disorders. Understand proposed mechanisms of action for therapeutic effects and adverse effects for each of the 3 classes of antidepressants 4. To appreciate the more common adverse effects and toxicities with antiepileptic therapy.induced and be able to Select the appropriate therapy of such cases. Contents: Outline of Antidepressants 1. antihistamines. 8. Drugs Used to Treat Grand Mal. side effects and doses 3. 6. Know the indications for the antidepressants. 4. 2. Understand the advantages of the serotonin-selective reuptake inhibitors (SSRI's). Contents: Major anti-parkinsonian agents: L-dopa. Understand the criteria for selecting one drug or class over another. 5. List the different drugs used for the treatment of parkinsonism. SSRI's 7. 3. MAO-I's. Know about the most important drug-food and drug-drug interactions of these drugs. 2. Introduction and Definitions 2. To understand the relationship between minimum alveolar concentration (MAC) and the Ostwald coefficient. Know the 3 classes of antidepressants and examples of each (TCA's. 7. Recognize that some cases of parkinsonism can be drug. Drugs Used to Treat Petit Mal (Absence) Seizures 7. pharmacokinetics. 3. To understand the signs and stages of general anesthesia. 9. Know the symptoms of overdose and the treatments. their mechanism Of action.

7 Opioid analgesics and antagonists: (2 CU): Objectives: 1. Anesthetic Potency 4. Contents: 1. Fixed Anesthetics 7. alcohol) 9. 5. Recognize the situations in which these drugs can be applied with advantage 3. Understand the mechanism by which narcotic drugs relieve pain in the light of the discovery of the new brain peptide endorphins and enkephalins. Hepatic metabolism 4. NSAIDs in gout 65 . To understand the rationale for preanesthetic medications. Factors that influence absorption and elimination 3. physical dependence. Clinical Pharmacology 3. Absorption and Elimination of General Anesthetics 3. Drug Abuse . hypoglycemic drugs.Barbiturates and Other Sedatives . Introduction and Definitions 2.Inhalants 7.Stimulants . Basic Pharmacology of Opioid Analgesics: 2. naproxen and piroxicam) 7. metabolic tolerance.Hallucinogens . ketoprofen. Mechanisms of anti-inflammatory. uses and Interactions with other drugs. and functional tolerance. . The basic pharmacology and toxicology of NSAIDs (particularly ibuprofen. 2. Contraindications 6. Preanesthetic Medications 7. Appreciate the adverse effects and limitation of there drugs Contents: 1.Opiates and Opioids . Discuss the pharmacology of several mild analgesics 2. Signs and Stages of General Anesthesia 5. pharmacokinetics. anesthetics. Comparison of Inhalational Anesthetics 6. Colchicine and acute gout 2. addiction. Adverse interactions with other drugs (e. Contents: 1. Know the pharmacology. indomethacin. tolerance. List the important side effects which limit the use of these drugs Contents: 1. By the end of the course the student will: 2. Recognize the importance of drugs used in prophylaxis and treatment of gout 3. unwanted effects. Adverse effects and consequences of irreversible inhibition of cyclooxygenase inhibition 7.8 Antipyretic analgesics and non-steroidal anti-Inflammatory drugs: (2 CU): Objectives: 1. analgesic and antipyretic effects of aspirin 2. Toxicity and treatment of overdose 8. Dose-dependent pharmacokinetics 5.g.9 Drugs used in gout: (1 CU) Objectives: 1. anti-coagulants.Introduction: Define psychic dependence..

Calcium channel blockers .10 Psychopharmacology: (1 CU): Objectives: 1. Know the possible involvement of the renin angiotensin system and the effect of the anti hypertensive drugs on plasma renin activity 5. Introduction to Antipsychotics 2. Contents: 1. Understand the dopamine theory of schizophrenia. know the classification of the local anesthetics with prototype examples 2. Allpurinol 7. Know the different classes of antihypertensive drugs and realize that treatment of hypertension involves the use of a combination therapy in a good number of patients 3. Management of hypertensive emergencies 66 . contraindications and the proper selection of the antihypertensive drugs Contents: 1. 3. Be aware of the adverse effects.Angiotensin converting enzyme (ACE) inhibitors 3. understand mechanism of action. Current views on etiology of hypertension 2. Basic Pharmacology of LA 3.“atypical” antipsychotic agents. Appreciate why the thiazide diuretic are common components in most antihypertensive combined therapy 4. Toxicology 8. Therapeutic Effects and Adverse Effects 4. Appreciate the adverse effects of local anesthetic Contents: 1. Lithium (Li) 7. methods of application of the local anesthetics 3. Introduction 2. Outpatient treatment of hypertension 4. Understand mechanisms and sites of action proposed for therapeutic effectiveness and for adverse effects.1 Antihypertensive drugs: (3 CU): Objectives: 1.“typical” antipsychotics: . Understand the indications for these drugs.11 Local anesthetics: (1 CU): Objectives: 1. Uricosuric agents 4. Basic and clinical pharmacology of antihypertensive drugs: .Diuretics . Major Classes of Antipsychotics . Cardiovascular drug: (11 CU) 8. Be able to select the proper local anesthetic to meet the requirement of clinical Needs 4.Sympatholytics .Vasodilators . 3. 2. 3. Know side effects. Appreciate that because of lack of knowledge about the exact etiology of essential hypertension/ antihypertensive drugs with quite diverse mechanism of action are used 2. data supporting and refuting. 4. Clinical Pharmacology of LA 4.

Calcium channel blockers (Class IV) 5. ß-Adrenergic blockers (Class II) 3. a beta adrenergic blocker. Know the cardiovascular properties of digoxin. ß-Adrenergic blockers 8. Recognize the therapeutic application.5 Drug treatment of shock: (1 CU): Objectives: 1. Recognize that the use of propranolol. Miscellaneous 8. Nitrates and nitrites 2. Appreciate that digoxin and other glycosides are capable of causing any type of cardiac arrhythmias including those for which they may be prescribed 5. Sodium channel blockers (Class I) 2.2 Drugs in treatment of angina:(2 CU): Objectives: 1. Contents: 1. the adverse effects and precautions in the use of each class and possible drug interactions Contents: 1. Appreciate the importance of knowing the electrophysiology of the heart to help in understanding effects of cardiac glycosides 2.8. Calcium channel blockers 3. Appreciate that not every type of shock requires treatment 3. Recapitulate the physiology of coronary circulation and the factors which increases oxygen demands 2. Other positive inotropic drugs 8. Appreciate that toxicity due to cardiac glycosides is common and know the different manifestations of this toxicity and its treatment 7.3 The cardiac glycosides and other drugs used in the treatment of congestive heart failure: (3 CU): Objectives: 1. Digoxin 2. prototype glycoside and its differences digitoxin and other glycosides 3. Recognize the poor therapeutic index of cardiac glycosides and be well acquainted with factors and conditions which may increase or decrease potency of these drugs 6. is a new approach to angina that emphasizes the importance of reduction of cardiac work in relief of angina Contents: 1. Recognize the therapeutic uses of the cardiac glycosides and know the pharmacological basis for such uses in heart failure and some cardiac arrhythmias 4. Understand the management of various types of she 2. Recognize the importance of the newer inotropic drugs and VD in the management of CHF. Appreciate that in order to understand the effects of the antiarrhythmic drugs it is necessary to get acquainted with physiology of normal rhythm and the possible mechanisms involved in the genesis of dysrhythmias 2. Appreciate the problem of angina as resulting from an imbalance between oxygen demand and supply in ischemic areas of the myocardium 3. their 67 . Potassium channel blockers (Class III) 4. Know the classes of drugs used in the treatment of shock. Know the classification of the antiarrhythmic drugs according to their effects of the cardiac physiology and their clinical uses 3.4 Antiarrhythmic drugs(2 CU): Objectives: 1.

cardiogenic shock. Ezetimibe 9. 3. Fibrate 3. Know the adverse effects. Pharmacology of Iron. Be aware of the methods for control and avoid the possible hazards of these drug 4. this class of drugs and drug in Contents: 1. Niacin (nicotinic acid) 2. Gemfibrozil 4. Pharmacology of oral anticoagulants 4. 9. Drug treatment of shock 9. Bile acid-binding resins 5. 6. septic shock. Understand the use of ion salts in iron deficiency 2. Appreciate the importance of these management of certain disease state 3. Acquire knowledge of the site and basic action of drugs modifying the coagulation 2. Pharmacology of heparin. vitamin B12 and folic acid. Understand the rationale in using vitamin B12 in anemia and the use of folic acid in megaloblastic and their interrelatioship in different bi reactions. adverse effects and interactions Contents: 1. Contents: 1.1 Hypolipidemic agents (1 CU): Objectives: 1. and hypovolemic shock 2. Know the different types of drugs the plasma lipoproteins level and be aware of possible mechanisms of action and their prophylaxis and treatment of atherosclerosis 2. The potential uses of erythropoietin and other hematopoietic factors in treating anemia 68 . Pharmacology of antiplatelet drugs.3 Antianemic drugs(1 CU): Objectives: 1. 2. Appreciate the toxicity of ion particularly in small children and its management. Anaphylactic shock. Be aware of the potential interaction of coagulants with other drugs Contents: 1. Pharmacology of fibrinolytic and antithrombotic drugs. Appreciate the limitation of the useful drugs in treatment and prophylaxis 3. 2. Drugs affecting blood: (3 CU): 9. 3. HMG-CoA reductase inhibitors.2 Drugs used in disorders of coagulation: (1 CU): Objectives: 1.

ACTH) 5. Proton pump (PP) inhibitors . Antidiarrheal Drugs 11. Be aware of the major endocrine disorders related to pituitary hormones and the preparations available for replacement therapy or diagnosis 2. FSH and Luteinizing Hormone. 6. 10. Drugs Used in Acid-Peptic Disease . Know the different thyroid hormones preparations and their main differences and indications 69 . Mucosal protective agents . TSH) 4. Laxatives 5.2 Thiyroid hormones: (and antithyroid drugs): (2 CU): Objectives: 1. Growth Hormone (Somatotropin. GH) 3. Be aware that drug treatment of peptic ulcer can provide symptomatic relief or Promote ulcer healing or both. contrast media and chenodexoycholic acid Contents: 1. Be aware that some drugs can aggravate peptic ulceration and should be avoided In such cases. Thyrotropin (Thyroid-stimulating Hormone. Antibacterial drugs 2.1 Hypothalamic and pituitary hormones: (2 CU): Objectives: 1. 2. Gonadotropins (Follicle-stimulating Hormone. appetite stimulators. 5. Antiemetic Drugs 4. 4. Drugs used in gastro-intestinal diseases: (6 CU): Objectives: 1. LH) 6. Know the different causes of nausea and vomiting ( the different antiemetics and Their special uses 7. Posterior Pituitary Hormones 11. Antacids . Recognize that some drugs can influence the rate of secretions of the pituitary hormones Contents: 1. First Semester. Drugs Promoting Gastrointestinal Motility 3. Histamine H2 antagonists . 3. Pharmacology III Course Code: 1801443 Credit Hours: 3+0=3 Academic Level: Fourth Year. Introduction 2. Recognize the role of histamine in mediating acid secretion and the presence of H2 receptors. Adrenocorticotropin (Corticotropin. Describe the pathway of the thyroid hormone biosynthesis and the site of action of the different antithyroid drugs 2. Prolactin 7. Know the different drugs used in the symptomatic treatment of diarrhea. Hormones and drugs used in some endocrine disorders: (14 CU): 11. Get acquainted with some miscellaneous drugs affecting the gastrointestinal tract indirectly as anorectic drugs. Know the classification of drugs used in treatment constipation and know their Special uses in certain situations.

Anion inhibitors.Thionamides.how contrast dyes are used to treat hyperthyroidism . Know natural and synthetic oestrogenic and progrestational hormones and therapeutic uses 3. their place in 5. mechanism. clinical use. Know the different classes of the oral hypoglycemic agents. Know the different insulin preparations and the merits of each preparation which will help in the proper selection in any given situation.Insulin. 4. Know the main actions of androgens and the androgenic substances used in replacement therapy and as anabolic agents 2. therapy and side effects. Actions 2. Adverse effects of GCs and contraindications 11. 4. Be aware of the adverse effects of the corticosteroids and how to minimize these adverse effects 4. mechanism of action and types of oral contraceptive pills. Contents: 1. Know the pharmacology of antithyroid drugs Contents: 1. 2. side effects. Pharmacology . mechanism. . diagnostic use .Radioactive iodine. Potency 4. therapeutic use. Pharmacology of oral contraceptives 70 . 3. toxicity .Iodide.4 Adrenocorticosteroids and adrenocortical antagonists: (2 CU): Objectives: 1. Know the composition. mechanism of action. and the route of administration. toxicity .5 Gonadal hormones and inhibitors: (2 CU): Objectives: 1. Drug treatments of hyperthyroidism: . Use of THs in deficiency states 2. Uses 5. Know some drugs used as ovulation inducers Contents: 1.Oral antidiabetics. contraindications 11. 2. Know the different preparations available for systemic and topical applications 3.3 Pancreatic hormones and antidiabetic drugs: (4 CU): Objectives: 1. Be aware of the reactions to insulin and particula1 the seriousness of 3. Pharmacology of estrogens and progestin 2. and the side effects and contraindications for the use of these pills. Be aware that withdrawal of systemic corticosteroid therapy should be gradual and realize the danger of sudden withdrawal 5. Be aware of the natural and synthetic corticosteroids and classification of the steroids 2. hypoglycemia. Types 3. Recognize the use of adrenocorticol antagonists for tumor treatment Contents: Pharmacology of corticosteroids (glucocorticoids and mineralocorticoids): 1. mechanism. Treatment of different types of DM 11.

Inhibitors of protein synthesis (IPS) . Urinary tract antiseptics 7. Pharmacology parathyroid hormone (PTH). Chemotherapy: (18 CU): 12 . Inhibitors of folate-dependent pathways . clindamycin. Know that antituberculous therapy more than one agent in order to minimize Drug resistant and toxicity is initiated with continued double drug Contents: 1.1.Aminoglycosides . 3. Know how to select the proper drug and administration 6. spectinomycin 4. Be aware of the combined antimicrobial its indications and its disadvantages 7. Pharmacology of testosterone and synthetic androgens 11. Recognize the classification of antituberculous drugs as first line and second line Drugs 2. Antimycobacterial agents 12.2 Antituberculous drugs: (2 CU): Objectives: 1. Be aware of some general concepts in antimicrobial therapy which would ensure effectiveness to therapy 2. Be aware of the different classes of antimicrobial agents 3. Inhibitors of cell wall synthesis (ICWS) . calcitonin and vitamin D in calcium homeostasis 2. Contrast treatment of hypoparathyroidism and hyperparathyroidism 12. Know the mechanism of action of antimicrobial 4. Drugs for leprosy 12.Other beta-lactams .Sulfonamides .Penicillins . 3. Recognize the role of secondary hormonal regulators of bone mineral homeostasis as well as the role of nonhormonal agents. this resistance 5.Other ICWS 3. erythromycins. chloramphenicol.6 Agents that affect bone mineral homeostasis: (2 CU): Objectives: 1. Be acquainted with the adverse effects antimicrobial agents Contents: 1. Contents: 1.Cephalosporins . Describe the probable mechanisms of action of the polyene 71 . Understand the role of both calcium and phosphorous in bone metabolism 2. General Principles of Chemotherapy 2. Pharmacology of first line antituberculous drugs 2. Be aware of the causes of treatment failure 8. Know the role of the principal hormonal regulators of bone mineral homoestasis.3 Antifungal agents: (2 CU): Objectives: 1. DNA gyrase inhibitors 6. Recognize the development of resistance to antimicrobial agents and how to minimize. The use of clomiphene for treatment of infertility 4.Tetracyclines.Trimethoprim 5.1 Antimicrobial drugs: (8 CU): Objectives: 1.

Antiprotozoal Chemotherapy 3. Antimetabolites 4. Know the different antiviral agents used in both treatment and prophylaxin of viral infections. 2.4 Antiviral chemotherapy and prophylaxis: (2 CU): Objectives: 1. To be aware of the different factors which may predispose the patient to adverse drug reaction and drug toxicity. Griseofulvin 5. 2. eradication or treatment of Helminthiasis and protozal infections Contents: 1.5 Anthelmintics and antiprotozoal agents: (2 CU): Objectives: 1. without exception. inhibitors of late protein synthesis inhibitors of assembly or release of viral particles. Terbinafine 12. Contents: 1. Membrane-active agents 3.6 Cancer chemotherapy and immunosuppressive: (2 CU): Objectives: 1. Apply the knowledge to the prophylaxis. Miscellaneous Topics: (4 CU): Objectives: 1. Be aware of the possible hazards of using these agents and the characteristic signs of toxicity resulting from the administration of antineoplastic agents 3. 4. are potentially harmful specially when The rational use of drugs is lacking and when the proper knowledge of drug pharmacology is inadequate. Recognize their adverse effects and the limitations drugs used in viral infections. Describe the clinical uses and pharmacokinetics of amphotericin B. Pharmacology of immunosuppressive drugs. griseovulfvin. 13. Be familiar with the clinical uses of immunosuppressive agents in certain autoimmune diseases or organs transplantation Contents: 1. Ketoconazole. azoles. Antifungal azoles 2. 3. 2. interferons. 1. antifungal Antibiotics. zidovudine pyrimidine 2. fluocytosine. griseofulv and fluocytosine. Purine analogues. Anthelminthic Agents 12. Be aware that all drugs. Indicate the major toxic effects of systemic antifungal drugs and Griseofulvin. Recognize that drug use may lead to different types of adverse reactions. Recognize that drugs that affect the fetus during pregnancy or baby 72 . while others are unpredictable as they occur only in certain susceptible individuals such as drug allergy and idiosyncrasy. amantadine. Identify the main topical antifungal agents. Be acquainted with the different types of drugs used in cancer chemotherapy and their biochemical mechanisms 2. 4. fluoconazole. other inhibitors of nucleic c synthesis. Know the different drugs used for the treatment of helminthiasis and protozoa Indigenous to region 2. 12. Basic Principles of Antiparasitic Chemotherapy 2. Pharmacology of Anticancer drugs. 3. Gamma globulins. Contents: Pharmacology of: 1. Some of these reactions are predictable as they are extension of the intrinsic Pharmacological actions of drugs. 2.

7. Contents: 1. Pharmacovigilance. Therapeutic drug monitoring. 7. 6. Terminology. Pharmacoeconomics. 5. Pharmacovigilance. 3. Risks of pharmacotherapy in pregnancy and lactation. 6. 4. Risks of pharmacotherapy in geriatrics. Pharmacoeconomics. Be acquainted with the meaning of different subjects in pharmacology as drug development. Therapeutic drug monitoring. & Pharmacogenetics. Factors which may predispose patients to adverse drug reactions. Categorize the drugs according to safety during pregnancy and lactation. 5. Pharmacogenetics and Drug Information. definition and types of adverse drug effects. during lactation. Drug development process. Be aware about the effect of different categories of drugs on old patients. 2. 73 .

74 . Dale. Limbird & Gilman: Goodman & Gilman. 5. Depression 10. Rang.. Anemia and dyslipidemia. 4. Peptic ulcer. Katzung: Basic and Clinical Pharmacology. Ischemic heart diseases 5. Clinical Pharmacology Course Code: 1801444 Credit Hours: 2 + 0 =2 Academic Level: Fourth. Bronchial asthma 6. 13. the student will be ale to: 2. Objectives: 1. 4. 5. Anxiety an schizophrenia 12. 3. Seizures 9. Upon completion of this course. 4Ed 2. Describe the rationale for choosing certain drugs to treat individual patients and diseases. Ritter & Moore: Pharmacology. Timothy Mant A Textbook of Clinical Pharmacology. Recognize the underlying principle of the pathophysiology of disease and basic facts of pharmacotherapy that must be interdigitated in order to select drugs and establish therapeutic objectives. Upper and lower respiratory tract infection. 3. Churchill Livingstone. Urinary tract infection 14. Contents(28 CU): 1. Identify side effects necessary to monitor during drug therapy and describe symptoms of toxicity of drugs. Foster an attitude of advising the physician based on basic knowledge of therapeutics. Second semester. Grahame-Smith & Aronson: Oxford Textbook of Clinical Pharmacology and Drug Therapy. Hypertension 3. Act as a knowledgeable member of the health care team in the area of pharmacology. 8. Migraine and glaucoma 2. Lionel Lewis. Pain and inflammation 11. Identify major classes of drugs used in the clinical setting. 7. McGraw-Hill. Appleton & Lange.s the Pharmacological basis of therapeutics. References: 1. Congestive heart failure 4. 6. Pulmonary TB. Hardman. James Ritter. 7.

Particulate matter toxicity: silica dust and asbestosis. The mechanism of action. and as well as industrial toxins. 5. Objectives: 1. sulfur oxide. Formaldehyde toxicity 3. Know the types and sources and health effects of environmental pollutants. 4. and Pharmaceutics. 10. 2. Understand toxicology terms and definitions such as toxicity. iatrogenic toxicity. Air Pollutants:(1 CU) 1. photoallergy. 9. ozone 75 . risk. Basic analytical methods for measuring concentrations of toxic substances in the air. Know toxicology and its subdivisions. Common household poisons. The discipline is focused on toxicological aspects of all factors affecting the human organisms. 5. Contents: 1. Toxicological Evidence. Toxicokinetics . routes of exposure. clinical effects and treatment of important toxicants. 2. Introduction to Toxicology: (2 CU): 1. Dose time – effect relationships. First semester. water. Understand the environmental considerations of chemicals. botanical and chemical sciences. aspects of toxic effects. toxic effects. 13. and ecology. 4. 4. phytotoxicity. duration of exposure. qualitative and quantitative 3. 6. Special attention is paid to toxic substances which are present in the air. 2. idiosyncrasy. Introduction. metabolic pathways. 6. 2. 11. Recognize the antidotes of different toxins. Review current concepts in risk communication and provide practical outreach experience. chemical allergies. Understand the effects of different toxicants and stressors in terms of target effect on the cellular-.and whole body-levels. Pharmacology. 3. Some important toxicants carbon monoxide. distribution and elimination of xenobiotics. Know deposition and absorption of toxicants by the lung. LD50. hazard. Understand the diagnosis and management of poisoned patient. plants. 8. Relate applied toxicology principles and community health practices. quantitative aspect. water. 14. 7. Pre-requisites: Organic chemistry. pharmacognosy and drug development. organ system. 12. Biotransformation : detoxication and bioactivation. Absorption. Description: Toxicology is a science which studies toxicological aspects of pharmacology. and environment. mechanisms of distribution within the body. and elimination processes. side effect. food and in biological materials and the procedures in estimating drug toxicity are of primary importance and are taught in practical training settings which were created recently as an independent and obligatory subject followed by an examination. Know major sources of information in toxicology. description of sub disciplines of toxicology. food. Classify the different routes of toxic exposure. 7. Toxicology Course Code: 1801545 Credit Hours: 2+1=3 Academic Level: Fifth. Understand the basic principles and applications within the science of toxicology. Know the incidence of acute poisoning.

kepone. thallium. Chlorinated Hydrocarbon Insecticides:DDT. silver. clinical effects and treatment of: 1. 3. The various methods the gastrointestinal tract can be decontaminated. aluminum. clinical effects and treatment of: 1. copper. Ectoparasiticides lindane. pyrolan.Ethanol 3. leptophos.Aliphatic hydrocarbons 2. phosphine 7. Bipyridyl Herbicides 3. organic lead. dimetilan. Carbamate Insecticides: aldicarb. zectran 4.Benzene 8.3. carbaryl. fenitrothion. Fumigants: cyanide.Chelators and Heavy Metals: (2 CU) . cyclodienes. pyramat. Manganese. aminocarb. inorganic mercury 2. dichlorvos. zinc phosphide. dimetan. nitrobenzene. Chlorophenoxy Herbicides 2. alpha-naphthyl thiourea.Toluene 4.Methanol 4.Glycols 6. Organophosphorus Insecticides azinophos-methyl. strychnine 6. deferoxamine 8. Cadmium. carbofuran. mirex. clinical effects and treatment of methemoglobin- forming chemicals 1. clinical effects and treatment of: 1. cobalt. methylbromide. penicillamine. pyrethrum 5. diazinon.Halogenated aliphatic hydrocarbons 7. Poisons can be treated with hemodialysis or hemoperfusion 4. Insecticides: (4 CU) . fluoride. hexachlorides. propoxur. Direct nitrites 2. edetate calcium disodium.The mechanism of action. Dimercaprol. phosphorus. succimer. Herbicides and Fungicides: (1 CU) . parathion. arsenic.The mechanism of action. Dinitrophenol Herbicides 7. 2. etc. rotenone. selenium. trichlorfon 3. Solvents:(2 CU) . zinc 3. The clinical features and key interventions for toxicity produced different drugs or classes of drugs. pyrethrins 6. Methemoglobin-forming Chemicals: :(1 CU) . parathion-methyl. malathion. Management of Poisoned Patient: (2 CU) 1.The mechanism of action.The mechanism of action. sodium fluoracetate. organic mercury. aniline. Indirect p-aminophenol. dibromochlorpropane. Botanical Insecticides nicotine. The laboratory and X-ray procedures that are useful in clinical toxicology. ethylene dibromide. lindane.The mechanism of action. chlorfenvinphos. p-aminopropiophenone 5. osmolar gap. toxaphenes 2. Rodenticides wafarin. red squill. clinical effects and treatment for intoxication with the following solvents: 1. including anion gap. malathion. benzene. methomyl. toxaphene. dimethoate. mercury vapor. isolan. thallium.Isopropanol 5. Inorganic lead. as 76 . arsine.

Nervous System. Standard analytical methods for the test chemicals. 3. 11. Respiratory System (2 CU) 12. pre-natal and post-natal development and in vitro methods. disadvantages and cautions of each 5. Methods for the collection. antidepressants. general fertility and reproductive functions in males and females.Anticholinergics 5. 2004. with blood or tissue proteins or DNA. 5. 8. Medical-legal aspects of poisonings. Awareness of the health and welfare requirements of common laboratory animals. hallucinogens 4. 2. subacute. NJ 77 . Identification and quantification of poisons. Inc. teratology. References: 1. Preparations of lab reports. 3rd edition. 2. dosing procedures. adducts in urine. The urinary excretion of chemicals can be enhanced 7. their handling. well as advantages. handling and storage of blood and urine samples. 14. regulatory control of animal experimentation.Analgesics and Anti-inflammatory drugs 2. Developmental neurotoxicity tests: behavioral patterns in experimental animals. 3. Orientation. and clinical signs in treated and control animals. Post-mortem methods. Organ Toxicity – Liver and Kidney. including functional observations. 13. Sampling. Clinical observations.Opioids 3. and between spot samples and integrated measures. 10. Organ Toxicity . Weight change. humane killing. hoboken. Toxicity Testing (1 CU) 14 Therapeutic drug monitoring (2 CU) 15. The distinction between measures of acute and chronic exposure. 4. Forensic Toxicology: (2CU) 1. Macroscopic identification of major organs and recognition of pathological abnormalities. John Wiley and Sons. and chronic toxicity. Fetal and neonatal examinations: recognition of gross teratological abnormalities. The mechanism of action of ipecac and apomorphine 6. 12. Immune System (1 CU) 13. 6. anesthetic procedures and humane killing procedures. Establish relationship between tissue residual level and probable cause of death Practical: 1. Drug Toxicity: (4 CU) 1. A Textbook of Modern Toxicology.CNS stimulants and depressants. 9. apparent signs of toxicity.Endocrine System. Reproductive toxicology study: multigeneration studies. 7. Principal techniques of exposure assessment.Cardiovascular drugs 10. Antidote 9. methods of evaluation and preparations. Reproductive Toxicity (1 CU) 11. Determination of acute. Hodgson. including urinary levels of compounds or a metabolite.

7. Second Edition by Ronald D. Ellenhorn’s Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 4. 3rd Edition. Experimental Toxicology: The Basic Issues by Diana Anderson. 8. Basics of Toxicology: Preserving the Legacy. M. 6. M. Williams and Wilkins. 78 . . Ellenhorn. Prediction and Risk by Adam Woolley.2. Hood. John Timbrell.)..J. C. Kent (J. 2002. Wiley & Sons. Klaassen: Casarett and Doull. Taylor and Francis Publishing 3. Conning D. A Guide to Practical Toxicology: Evaluation. 5. Toxicology: the basic sciences of Poisons. Introduction to Toxicology. MacGraw-Hill. Developmental and Reproductive Toxicology: A Practical Approach.

Umm Al-Qura University Faculty of Pharmacy Department of Pharmacognacy Modules 2008 79 .

I. Herbs. 2. Animals. classification. official and unofficial drugs. classification. 14. Siddha and Allopathic systems practiced in India. collection and processing of medicinal plants. which are in current use. with emphasis on traditional medicine practice. Ayurveda.and microscopical characteristics. Classification of crude drugs § Based on alphabetical. pharmacological. Know botanical aspects. modern concept and scope of Pharmacognosy. Describe and select appropriate biological assay methods for the screening of a given product and bio-guided isolation. Describe types of culture techniques. 6. inorganic matter. 3. cultivation and processing of medicinal plants. Design a culture system laboratory 11. 13. students will study both official and locally made crude drugs. Further. morphological. Representative drugs from different morphological sources will be discussed in detail. The geographical distribution. 2. Show the contribution of traditional medicine to modern medicine. Significance of Pharmacognosy in various systems of medicine viz. Show the importance of alternative systems of medicine. Definition of drug § Sources of crude drugs viz. involving the description of their macro. 12. collection. nomenclature. advantages and disadvantages 10. Apply the principles of chemotaxonomy to solve taxonomical problems. Pharmacognosy I Course Code: 1802311 Credit Hours: 2+1=3 Academic Level: Third Year. 3. First Semester. organized and unorganized drugs. Provided with general information on cultivation. nomenclature. Contents: 1. Introduction: The Pharmacognosy course introduces students to botanical aspects. and processing of medicinal plants. chemical constituents and their uses will be emphasized. which will be made even clearer when students go for field work to appreciate medicinal plants in their natural environment. 15. Describe appropriate examples of bioactive compounds from natural sources 9. cultivation. Describe and utilize the methods used for selection of potential medicinal plants for biological screening 7. their applications. plant 80 . Unani. 4. chemical and taxonomical methods. 5. Show the role played by growth substances in plant breeding. Introductory Pharmacognosy § Historical development. Theoretical: Objectives: 1. Homeopathic. 8. Advise the community on the importance of conservation of bio- diversity.

tannins. seed. glycosides. Lamiaceae. stomata. Scrophulariaceae. Study of diagnostic characters of families mentioned in the theory. 2. Monocot). Practical: 1. 4. Gnetaceae (Ephedra). stem (Dicot. polyploidy. Acanthaceae and Euphorbiaceae. phloem fibres. polysaccharides. Leguminosae (Caesalpinaceae. Rutaceae. leaves and roots. 81 . alkaloids. 9. 7. Carrageenan and Cetraria). anatomical structures of bark. di. calcium oxalate crystals. trichomes. type of soils. ii) Fungi: Eumycetes (Ergot. Mimosaceae. tannins. Microscopical studies of basic tissues. carotenoides. Papaveraceae. tissue culture and marine sources. clearing agents. fruits. Diatoms. classification and chemical tests of: Carbohydrates. mutation and hybridization in medicinal plants. leaf. fertilizers. § Factors influencing variability in drug activity. Alginic acid. Staining and surface preparation. Apiaceae. II. iii) Gymnosperm: Pinaceae (Turpentine. Monocot). Mushrooms. saponins. drying. Colophony). and Lycopodium).and tri-terpenes. seeds and monocot and dicot stems. Solanaceae. steroids. bark. Asteraceae. Root (Dicot. 6. starch. Role of herbal drugs in national economy. Papilionaceae). Yeast. Antibiotics. Principles of plant classification § Diagnostic features and medicinal significance of important plants with special reference to: i) Algae: Rhodophyceae (Agar. Cultivation of herbal drugs. phenolic compounds. mono-. storage and transport methods. v) Pteridophytes: Male fern. 4. Production Factors § Factors involved in the preparation of herbal drugs for market from cultivated and wild sources including collection. flavonoids. Microscopic preparation. Phytoconstituents of medicinal importance § Introduction. resins and proteins. fruits. iv) Angiosperm: Apocynaceae. Convolvulaceae. iridoides and amino acids. chemomicroscopic reagents. 8. glycosides. Techniques in microscopy § Details of mountants. Rubiaceae. 3. General chemical tests for alkaloids. plant hormones and their applications. 5. Study of morphological and histological characters of crude drugs § Ergastic cell inclusions.

natural pesticides and insectisides regarding the geographical distribution. classification. with emphasis on traditional medicine practice. 15. Contents: 1. chemical constituents.and microscopical characteristics. 8. Biosynthesis § Formation of primary and secondary metabolites. advantages and disadvantages 10. Design a culture system laboratory 11. 4. which are in current use. Provided with general information on cultivation. their applications. Describe types of culture techniques.and microscopical characteristics. Further. collection and processing of medicinal plants. 2. chemical constituents and their uses will be emphasized. 14. Describe and select appropriate biological assay methods for the screening of a given product and bio-guided isolation. 12. TCA cycle. involving the description of their macro. which are in current use. Apply the principles of chemotaxonomy to solve taxonomical problems. structures activity relationship and their uses will be emphasized. 13. which will be made even clearer when students go for field work to appreciate medicinal plants in their natural environment. Show the contribution of traditional medicine to modern medicine. cultivation. collection. collection. drugs of animal origin. Introduction: § Study both official and locally made crude drugs. students will study both official and locally made crude drugs. The geographical distribution. and processing of medicinal plants. § Study of toxic drugs. § Representative drugs from different morphological sources will be discussed in detail. § Evaluation of contents by the use of analytical chromatography. 5. Shikimic acid pathway. nomenclature. Advise the community on the importance of conservation of bio- diversity. Describe and utilize the methods used for selection of potential medicinal plants for biological screening 7. Representative drugs from different morphological sources will be discussed in detail. involving the description of their macro. Objectives: 1. Describe appropriate examples of bioactive compounds from natural sources 9. cultivation. Pharmacognosy II Course Code: 1802312 Credit Hours: 2+1=3 Academic Level: Third Year. methods of separation. Study of Calvin cycle. 3. which will be made even clearer when students go for field work to appreciate medicinal plants in their natural environment. 6. Embden-Maerhoef 82 . Show the role played by growth substances in plant breeding. Second Semester. Show the importance of alternative systems of medicine. Know botanical aspects.

Pyrethrum. beeswax. pathway. 3. Ficin. sensory and chemical characteristic of shellac.ii) Stem: Ephedra iii) Root: Rauwolfia. gelatin. Bromalain. 4. vein termination number. Silk and Wool. silk. isoprenoid pathway. lanolin. Pancreatin. cochineal. stomatal number. woolfat. Plantago v) Bark: Cinchona. 5. lipids and volatile oils. Cotton. health food. chemical test and microscopy of: Cotton. Coriander vii) Wood: Quassia. fumigants and rodenticides. preparation. Papain Bromalain. Herbarium § Preparation of herbarium sheets and their importance in authentication of plants. mycotoxins. Natural pesticides and Insecticides § Tobacco. gelatin. and kieselghur. lard. Glycyrrhiza iv) Seed: Nux vomica. palisade ratio. 6. Cinnamon vi) Fruits: Fennel. Ryania. Enzymes § Biological sources. wool regenerated fibres. prepared chalk. kaolin. Datura. Introduction to herbicides. Cevadilla. spermaceti. Quantitative microscopy of Vinca. Pepsin. Lycopodium spore method. Biosynthesis of carbohydrates. asbestos. spermaceti. Microscopic and chemical tests of the following powdered drugs: i) Leaf: Senna. Drugs of Animal origins § Shellac. honey. musk. Yeast. Hyaluronidase and Stryptokinase. Datura and Senna leaves. fungicides. Practical: 1. honey. 8. 2. lanolin. Identification through morphological. woolfat. cosmetic and photosensitising agents. sweeteners. 9. narcotics. vein islet number. hallucinogens. toxic mushrooms and toxic plants. Toxic Drugs § Study of Allergens. Turmeric ix) Flowers: Clove. cantharides. beeswax. Trypsin. Plant Products § Introduction to plant bitters. characters and uses of Diastase. Yeast. Quantitative microscopy § Determination of stomatal index. Pencillinase. 3. Pharmaceutical aids § Biological sources. acetate hypothesis. Neem. Micrometers and measurement of microscopic characters. viii) Rhizome: Ginger. cantherides. 7. lard. Diastase. 83 . Papain. 2. cochineal. Urokinase.

chemical constituents. their applications. Show the contribution of traditional medicine to modern medicine. chalmooogra oil. Agar. adulterants and uses of: Starches. Pectin. collection and processing of medicinal plants. nomenclature. 6. cod liver oil. cultivation. Carbohydrates § Biological sources. 8. cultivation. Plantago. Contents: 1. methods of separation. chemical constituents. Describe types of culture techniques. lipids and volatile oils tannins. classification. sesame oil. Bael. Honey. 13. Show the role played by growth substances in plant breeding. Acacia gum. 2. Sterculia. which will be made even clearer when students go for field work to appreciate medicinal plants in their natural environment. shark liver oil. chemical constituents and their uses will be emphasized. structures activity relationship and their uses will be emphasized. students will study both official and locally made crude drugs. Show the importance of alternative systems of medicine. Provided with general information on cultivation. Describe and utilize the methods used for selection of potential medicinal plants for biological screening 7. neem oil. collection.and microscopical characteristics. 12. 3. collection. Describe appropriate examples of bioactive compounds from natural sources 9. 14. Further. Tannins 84 . advantages and disadvantages 10. and alkaloids. regarding the geographical distribution. first semester. and processing of medicinal plants. Pharmacognosy III Course Code: 1802311 Credit Hours: 2+1=3 Academic Level: Fourth. kokum bitter. Sodium alginate. adulterants & uses of: Arachis oil. 4. Representative drugs from different morphological sources will be discussed in detail. Describe and select appropriate biological assay methods for the screening of a given product and bio-guided isolation. which are in current use. Introduction: § Study both official and locally made crude drugs. rice bran oil. § Study of Carbohydrates. Design a culture system laboratory 11. which are in current use. Advise the community on the importance of conservation of bio-diversity. 2. Guar gum. cotton seed oil. Apply the principles of chemotaxonomy to solve taxonomical problems. 5. castor oil. Objectives: 1. Know botanical aspects. guggul lipids. with emphasis on traditional medicine practice. § Evaluation of contents by the use of analytical chromatography. chemical constituents. 15. Lipids § Biological sources. The geographical distribution. involving the description of their macro. 3. Tragacanth. olive oil. glycosides. which will be made even clearer when students go for field work to appreciate medicinal plants in their natural environment.

Physostigma. Fennel. Cassia. chemical test and uses of: pale catechu. Ephedra. Cumin. chemical constituents. aloe. Clove. Thevatia. Ipecac. Plantago. ruta. Dill. Preparation of herbarium sheets and monograph on one of the collected plant during tour. identification test. formation and chemical nature. quillaia. cinchona and opium alkaloids. Practical: 1. Anise. Clove. Black catechu. dioscorea. adulterants and uses of: Benzoin. quassia. senega. 4. Tolu balsam. Terminalia belerica. Asafoetida. Gaultheria. Chenopodium. Stramonium. Caraway. Guargum. chemical constituents. Sandal wood. 7. chemical constituents. Rauwolfia. Nutgalls. Nux vomica. Vinca. Capsicum. Sterculia. Citronella. Pharmacognosy tour for field collection of medicinal and aromatic plants. 2. Nux vomica. squill. Tea. (2 Weeks) 5. Coffee. Cinnamon. Duboisia. thevetia. Biosynthesis of tropane. Acacia gum. Eucalyptus. adulterants and uses of: Digitalis. Sesame oil. withania. Biological sources. Terminalia chebula. Peru balsam. Microscopy of: Datura. strophanthus. Resinous drugs § Classification. 4. § Biological sources. Vasaca. cascara. senna. Biological sources. Hyoscymus. Cinchona. Peru balsam. Lobelia. Veratrum. Opium. Ephedra. Biosynthesis of Cardiac and Anthraquinone glycoside. Tragacanth. Nux vomica. Colophony. Bitter almond. Jalap. Lemon grass. Mentha. glycyrrhiza. Aconite. Chemical tests of: Starches. Asafoetida. Myrrh. Cinchona. Aconite. 6. Lemon peel. Podophyllum. adulterants and uses of: Black pepper. Alkaloids § Biological sources. Cardamom. Benzoin. Tannic acid. chemical constituents. Turpentine. Colocynth. Orange peel. Pale catechu. chemical constituents. black catechu. Solanum xanthocarpum. Ginger. rhubarb. Ajowan. Tolu balsam. Coriander. Belladonna. Colophony. gentian. Palmarosa. Pilocarpus.. Ipecac. Cinchona. Star anise. Terminalia arjuna. Turmeric. 3. Rauwolfia. Fennel. Clove. Agar. Cinnamon. ginseng. Aloe. Nutmeg. Ipecac. Quassia. Cannabis. Kurchi. Spearmint. Volatile oils § Biological sources. 5. wild cherry. Colchicum. 85 . adulterants and uses of: Areca nut. Caraway. Identification of organised drugs studied in theory on the basis of morphological and sensory characters. Ergot. Glycosides § Nature and classification. Cotton seed oil. Cinnamon. Thevetia. Coca. Colchicum. oleander.

Shikonin and Taxol. Objectives: 1. production of secondary metabolites. 2. Show the role played by growth substances in plant breeding. Evaluation of drugs by organoleptic. Diosgenin. viz. Tannic acid. 8. WHO guidelines. involving the description of their macro. nomenclature. Describe appropriate examples of bioactive compounds from natural sources 9. advantages and disadvantages 10.and microscopical characteristics. chemical constituents and their uses will be emphasized. Plant Biotechnology § Tissue culture. Application of column. physical. Glycyrrhizin. Describe and select appropriate biological assay methods for the screening of a given product and bio-guided isolation. their applications. chemical and biological methods. application of plant biotechnology. immobilisation of cells and enzymes. Callus and suspension culture. Further. 6. 15. Quinine. paper and thin layer chromatographic techniques for the isolation of phytopharmaceuticals. proteins. Ephedrine. Contents: 1. Hesperidine. Nutritional requirements. Andrographolides. glycosides. which will be made even clearer when students go for field work to appreciate medicinal plants in their natural environment. 3. Biotransformation. Solanine. Representative drugs from different morphological sources will be discussed in detail. Provided with general information on cultivation. collection. collection and processing of medicinal plants. Describe types of culture techniques. Piperine. 14. Show the importance of alternative systems of medicine. Gene transfer in plants. lipids. 86 . 12. Gu ggul lipids and Katha industry in India. Methods of adulteration § Deterioration of herbal drugs by insect. Advise the community on the importance of conservation of bio-diversity. bioflavonoids. Rutin. 3. Apply the principles of chemotaxonomy to solve taxonomical problems. which are in current use. Pectin. characterisation and estimation of: Caffeine. 2. 4. Know botanical aspects. 13. Design a culture system laboratory 11. 4. steroids. Show the contribution of traditional medicine to modern medicine. Isolation Techniques § General methods used for the isolation and characterisation of alkaloids. Describe and utilize the methods used for selection of potential medicinal plants for biological screening 7. and processing of medicinal plants. volatile oils. Phytopharmaceuticals § Isolation. with emphasis on traditional medicine practice. microscopic. cultivation. second semester. Menthol. 5. students will study both official and locally made crude drugs. The geographical distribution. Calcium sennosides. classification. Berberine. Eugenol. terpenoids and resins. Pharmacognosy VI Course Code: 1802414 Credit Hours: 3+1=4 Academic Level: Fourth.

Morphology of traditional herbal drugs. sources. Lehsun (Allium sativum). Sidha. Intellectual Property Rights with special reference to phytoconstituents. Ghrita and Bhasms. Lipids. Cumin and Lemon grass. Asoka (Saraca indica). Tulsi (Ocimum sanctum). 87 . Giloe (Tinospora cordifolia). Regulation pertaining to trade drugs. Henna. Saffron (Crocus sativa). Unani. 9. and Vinca. 3. Worldwide trade of crude drugs and volatile oils § Plants based industries and research institutes. Tailia. Extractive values and foreign organic matters in herbal formulations. 6. Valerian (Valerian officinalis). Herbal cosmetics § Shampoos (soapnut). Sennosides and Quinine. Tea). Quality control and Standardization of herbal drugs § Extractive values. Cinchona. 8. Tannic acids. Henna). Herbal formulation of Shampoos. Chinese and Homeopathic systems of medicines. Isolation of Starch. 2. Conditioners. Determination of Moisture content. 5. Isolation and TLC profile of Total alkaloids: Nu x vomica. Swelling factor. Quinine and Anthraquinone glycosides. (Amla. Isolation and TLC profile of volatile oils of: Eucalyptus. 7. Unani formulations like Majooms. Hibiscus. Kalmegh (Andrographis peniculata). Tea. spectroscopic techniques and assay methods. Brahmi ( Bacopa monnieri and Centella asiatica). HPTLC and HPLC) for determination of chromatographic markers. active constituents and uses of: Punarnava (Boerhavia diffusa). ash values. 5. § Determination of heavy metals in herbal preparation and alcohol contents in Aristas and bhasams. preparation of Ayurvedic formulations like Aristas. Resins. 6. chromatographic techniques (TLC. Ghutika. Skin care (Aloe. Shankhpushpi (Convolvulus microphylla).. Preparation and evaluation of herbal drugs. Chirata (Swertia chirata). Artemisia (Artemisia annua). Shilajit. Cineole. Estimation of Citral. Churna.7. Hair darkeners (Amla. Salai (Boswellia serrata). Practical: 1. Turmeric). Traditional herbal drugs § Common names. Ash value. Avaleha. Rauwolfia. Herbal formulations § Principles involved in Ayurveda. Guggul (Commiphora mukul). Balsamic acid. Asava. 8. 4. Carvone. Safoofs. § Quality control and rational use of herbal drugs as per WHO guidelines.

Umm Al-Qura University Faculty of Pharmacy Department of Pharmaceutics Modules 2008 88 .

Preparation of some dosage forms. Introduction to Pharmaceutical calculations (2 CU): .density. ear and nose). such as solution.the metric system of weights and measures. will be involved. 89 . prescription terminology. 8. . individual powders. rectal. including prescription compounding and patient specific determinations.Posology and dosage regimen. Formulate liquid. mixture and powder pharmaceutical products. parenteral and topical routes of drug administration. Use pharmacopeias and other sources of information. Introduction to Pharmaceutical calculations (continue) (2 CU): . Define solubility and know its various expression 7. 3. Theoretical: Objectives: 1. 9. 3. solutions. pharmacopeias and formularies. . Introduction to Pharmaceutical calculations (continue) (2 CU): . suspensions.calculation of doses for children. Appreciate the need for accuracy and thoroughness in manufacture of pharmaceutical products.The prescription. . creams. 4. Students will apply appropriate mathematical concepts found within the practice of pharmacy. Description: This course includes an introduction to the history of pharmacy. main parts of prescription. Pharmaceutics I Course Code: 1803231 Credit Hours: 2+1=3 Academic Level: Second Year. . the principles of drug administration. emulsions. tablets.conversions.Different types of prescriptions. . the preparation of certain pharmaceutical dose forms. 4. Contents: 1. Types dosage forms (2CU): The oral. . ointments. Calculate isotonicity and osmolarity of pharmaceutical preparations. First Semester I. other common systems. suppositories and pessaries. the factors which influence the design of pharmaceutical dose forms. Bulk powders. systems of measurement and pharmacy calculations. capsules. measures and calculations used in pharmacy practice.Some fundamentals of measurements and calculations. mixtures and powder. 5.reducing and enlarging formulae. drops (eye.Sources of pharmaceutical information. Understand of the weights. Emphasis will be placed on improving and applying problem-solving skills for the needs of an individual prescription. specific gravity and specific volume. pills. Define a solution and describe all types of solution. 2. 2. Perform pharmaceutical calculations. . 6. Apply problem-solving skills for the needs of an individual patient within the practice of pharmacy.

fluid extracts. 11. Mixture containing slightly miscible liquids. . . linctuses.Effervescent powder . . Mixtures containing insoluble indiffusible solids. . . Mixture containing prescipitable forming liquids. Incompatibilities (2CU).Dusting powder 12. purpose and process. pharmaceutical solvents. correction and prevention with reference to typical examples. solubilization and co-solvency. .Dividing of powder . Types of pharmaceutical incompatibilities. mixtures… . tinctures. 2. elixirs. . mechanisms of solution.Bulk and divided powder .. .g. Maceration. 1. Solutions as oral dosage forms. 9. Vehicles for solutions. Solutions installed into body cavities. 2. including temperature. Miscellaneous mixture.Water and spirit. . . Solutions (continue) (2CU). Galinical preparations (continue) Extraction processes. e. . Solution formulation (2CU). Simple mixture. .Principles of formulation. solutes. Mixtures containing insoluble diffusible solids. . .Powder mixing . pH. deliquescent. . decoction. e.g. Solutions for external use. 1. . Powders (continue) (2CU). Manifestations. Physical and Chemical incompatibilities.Powder with special problems. Powders (2CU). Galinical preparations Infusion. . Isotonic solutions and electrolyte solution(2CU). complexation. concentration. .percentage solutions and allegation. efflorescent…. 90 . Mixtures (2CU). Factors effecting solubility. 10. . 3.

10. Publisher: Lippincott Williams and Wilkins. II. Ed. Stoklosa. Ansel and Mitchell J. UK. 5. e. Ansel's Pharmaceutical Dosage Forms and Drug Delivery System. Introduction to laboratory equipment ands procedures. Allen. 11. Practical: 1.. US Pharmacopoeia. Williams and Wilkins 2. Publisher: Lippincott.. Compounding of selected examples of mixtures containing insoluble diffusible solid. gargles. 3. British Pharmacopoeia. Problems based on how to manipulate the prescription 5. Popovich and Ansel (2005). Ed. 2. Martindale: The complete drug reference. Measuring techniques. Percolation. London. aromatic water. Pharmaceutical Calculations (2005). Compounding of selected examples of simple mixture. 8. ear drops. 4. Sweetman.. 6. 13. 4. Preparation of buffer solutions and isotonic solution. 91 . 9. liquid-liquid extraction. Ed. purpose and process. S.g. Compounding of selected examples of mixtures containing insoluble in-diffusible solid. Compounding of elixirs. Compounding of selected examples of solutions. 7. effervescent powder and effervescent granules. 3. Howard C. compounding of divided and bulk powder. 12. Galinical preparation References: 1.. Weighing techniques. Kathleen Parfitt. spirits. Preparation of Waters. C. aromatic waters. The Pharmaceutical Press.

Understand the production. dosage forms. Surface properties (3CU).Newtonian system. . Contents: Part I.Applications. 3. . the preparation of pharmaceutical dose forms. 6. the formulation.Factors affecting rheological properties. 2. 2. The preparation and characterization of liposomes will also involved. Rheology (3CU) . Describe the different types of radioisotopes used to make pharmaceuticals. 4. . 92 . capillary viscometer. falling-sphere viscometer. plastic. Theoretical: Objectives: 1. and drug delivery systems and formulation and preparation of certain dosage forms. properties and uses of aerosols. 3. Understand the principles of drug administration.Difinition and fundamental concepts .Rheograms. Second Semester I. and drug delivery systems and their composition.Non-Newtonian systems. describe methods of determination of surface/interfacial laws. Understand the physical and physicochemical behavior of drug molecules.properties contributing to rheological behavior. 7. Thixotropy. Perform pharmaceutical calculations. . Cup-and-Bob viscometer and Cone-and-Plate viscometer. emulsion. Rheology (continue) (3CU). . formulation and use of suspensions and emulsions. . This includes the study of interfacial phenomenon and viscosity The course also includes the study of the pharmaceutical principles for disperse systems. Differentiate various routes of drug administration and peculiarities of drug delivery systems designed for each specific route. pseudoplastic and dilatant flow.Determination of rheologic properties. Physical Pharmacy: 1. 5. Pharmaceutics II Course Code: 1803232 Credit Hours: 3 + 1 =4 Academic Level: Second Year. strain and strain rate. Description: This course involves the study of the physical and physicochemical behavior of drug molecules. suspension. dosage forms. Also studied are the mechanisms of drug release. Shear stress. explain the use of radiopharmaceuticals in nuclear pharmacy/medicine. Differentiate surface and interfacial tension. describe the solibilization phenomenon. the principles of dosage form design. aerosols.

stability of colloids. . classifications. Emulsions (3CU). optical.Physical Stability of suspensions. Organic molecular complexes.Introduction. . 10.Types of isotherms. . valve and actuator systems. 8.Flocculated and deflocculated systems. . 4. friction. containers. . . . . .Spreading coefficient and wetting. multimolecular and solid- particle adsorption. Colloids (3CU).Micellization and solubilization.Physical stability of emulsion and their evaluation.Systems of hydrophile-lipophile classification. Coarse dispersion. emulsion type. Part II: Disperse systems: 5. cohesion. . . atomizers. .Adsorption. .Classifications and structure. . 6.Product development.Non-pressure pack aerosols. . . .Applications in drug delivery. Complexation (3CU) . Measurement of surface and interfacial tensions. Surface properties (continue) (3CU). .Physical and chemical properties of lipids. . monomolecular.Metal complexes.Adsorption at liquid and at solid interfaces. . Surface free energy.The design and evaluation of suspension. . Hydrophilic- Lipophilic Balance (HLB). . .Physicochemical principles of aerosol science and technology. Surface and interfacial tensions.Applications in pharmacy.Types of colloidal systems. non-adsorption techniques.Emulsifying agents and their classification. .Complexation and Protein Binding. .Theories of emulsification. 9. Coarse dispersion.Aerosol propellants.Surface active agents. packaging. 93 . . factors influencing. their classification and stability. .Applications in pharmacy and medicine. . . . inclusion compounds. Pharmaceutical Aerosols (3CU).Electrical and steric stabilization of solid-liquid dispersions. adhesion. stability testing and performance evaluations of all types of aerosol products.kinetic. Suspensions (3CU). electrical properties. Liposomes (3CU). . 7.Suspending agents. . containers.Multiple emulsion and Microemulsions. manufacturing.

. dissolution and organoleptic properties and their effect on formulation. thermodynamic treatment of stability constants. Determination of the Hydrophilic/Lipophilic Balance (HLB) of surfactant(s). particle size.density. . .Routes of drug administration. Practical: 1.Mucosal drug delivery. Noyes-Whitney equation. Preformulation studies (3CU). Polymers as thickening agents. wetting. .Practical: II. 12. nasal mucosa. .Future trends in pharmaceutical and other biomedical uses of polymers. . 14. Rate and order of reactions (2CU). reduction. solubility.Study of chemical character of drug molecule like hydrolysis. . . 11. crystalline structure of complexes.Concept of preformulation.Factors affecting dissolution rate. Methods of analysis. complexation and drug action. stability and bioavailability.Pulmonary administration .gastrointestinal route (oral route) . 5.Study of physical properties of drug like physical form. 13. effect of electrolytes on the sedimentation volume.Gel formation. . Determination of the Critical Micelle Concentration (CMC) of Surfactant(s). Preparing polymer solutions. 3. effect of viscosity on the sedimentation volume. Determination of the sedimentation volume of suspensions. Polymer Science (3CU) . 94 . . etc. . shape. 4. oxidation. . recemization. . Drug Delivery Systems (3CU). . Pharmaceutical applications of polymers.Ocular Administration.Intrauterine. . polymerization. oral mucosal route. Phase separation. and their influence on stability of products. rectal and vaginal administration. .Parenteral administration . 2. pulmonary mucosa. theory of dissolution.Pro-drug approaches. Study of Flocculation and deflocculation of Kaolin Suspensions. Determination of the effect of glycerol concentrations on the viscosity.Dermal and trans-dermal delivery systems. dielectric constant. Mechanical properties of polymeric films.Introduction.

Preparation and characterization of liposomes. Martin's Physical Pharmacy and Pharmaceutical Sciences. Preparation of different types of emulsions (o/w and w/o types) using different methods. st 4. Pharmaceutics. Physical Pharmacy. 13. Drug dissolution. study of the effect of dissolution medium on the drug dissolution. Determination of the apparent partition coefficient of some drugs. the Science of Dosage Form Design. Determination of the stability of a hydrophobic colloidal sol. 9. Publisher: Lippincott Williams and Wilkins. Publisher: Lippincott Williams and Wilkins 2. 10. Determination of emulsion systems. 95 . 8. the Science and Practice of Pharmacy (21 edition). References: 1. The effect of change in volume and nature of the disperse phase on the stability of emulsion.. Remington. 12. Ed. Ed. Aulton (2006). 7. Construction of caking diagram. Sinko (2006). By determination of the Critical Coagulation Concentration (CCC). Williams and wilkinsons 3. Patrick J. Publisher: Lippincott. Alfred martin 4Th edition. Michael E. Publisher: Thomson Learning.. 6. Ed. 11.

Explain the methods and factors. Particle shape and surface area. granules. ointments and suppositories. . the preparation of pharmaceutical dose forms (tablets. 8. 10. . Particle size and size distribution. with practical examples . Porosity. Appreciate the need for accuracy and throughness in the preparation of pharmaceutical products. ointments. First Semester Objectives: 1. 6. shape and density of a powder and its impact on pharmaceutical processing/formulation. Micromeritics (2CU). Methods for determining particle size. 13. . Support the in-vitro and in-vivo characteristics of various dosage forms and their impact on the therapeutic effectiveness of the drug product. Discuss the role of formulation design and additives in modifying the drug bioavailability. Flow properties. Densities of particles. 3. 4. . 2. Understand of the formulation of specified dose forms. 12. drived properties of powder (2CU). Methods used for determination of powder density. Micromeritics (continue). Explain the science of modified release dosage forms. Explain the science of solid and semisolid dosage forms. Identify dermal and transdermal delivery system. Pharmaceutics III Course Code: 1803333 Credit Hours: 2 + 1 =3 Academic Level: Third Year. 7. Contents: 1. microcapsules. Discuss the role of formulation design and additives in modifying the drug bioavailability. . Drug release and quality control studies of each dose form will be discuss. Perform pharmaceutical calculations. which affect the formulation and production of solid dosage forms. . Sustained release formulation will also be addressed. 5. capsules. Point out the factors affecting formulation design. Description: This course introduces the student to the basic science of solid and semisolid dosage forms. Define and describe specified types of solid dosage forms. Understand the concept of particle size. 96 . Define the methods and factors affecting the formulation of suppositories. 14. creams and suppositories). the factors which influence the design of pharmaceutical dosage form. 2. 11. 9. The course will cover the formulation of different types of tablets.

4. Type of tablet coat (sugar. biological and pharmacokinetic properties. . 3. Sustained and Controlled Drug Delivery (2CU). Capping. dose 97 . 7. Tablet standers. 8. tablet machines (single punch and rotary press machine). spray congealing. friability). Methods of coating. material for production of hard geletin capsules. . . importance of base absorption and minim/gm factors in soft capsules. . Tablet coating. . . Advantage and disadvantages of capsule dosage form. . polymerization. .Methods of capsule production. 5. Tablet excepients . Tablets (continue) (2CU). Tablets (Continue) (2CU). . wet and dry granulation. Introduction to unit solid dosage forms . sticking. . . Tablets prepared by direct compression.Design and development. . coating pan and other techniques. Compaction.Microcapsulation by phase seperation co-acervation multiorifice. Formulation of tablets. Granulation techniques.Influencing design and performance of controlled release products. . size of capsules. complex emulsion.Types of microcapsules. spray drying. .Quality control. air suspension technique. thickness and diameter. film and compression coat). . Problems associated with tablet manufacture (e. Physico chemical. importance of microencapsulation in pharmacy.Materials and methods used in their formulation. .g Lamination. stability testing and storage of capsule dosage forms. Functional coat. disintegration. Microcapsulation (2CU). soft gelatin capsule shell and capsule content. . 6. Capsules (2CU). Quality control tests for tablets (weight variation. dissolution. . picking) . Tablets (2CU).

. 5. Particle size analysis of powders. designing. Transdermal therapeutic systems (TTS). direct compression. Novel Drug Delivery Systems :Introduction to novel drug delivery systems. Uniformity of weight and content testing and Friability 98 . types and mechanism of action. high velocity particles and stratum corneum bypass. Semisolid Dosage Forms (2CU). wet granulation. factors influencing penetration. In vitro and In vivo evaluation. 12. Suppositories (cont. 6. . types and preparation. evaluation and packaging. General formulation of semisolids (ointment and gel). 2. . packaging and evaluation. manufacturing procedure. .) . Novel mechanisms and devices to enhance skin delivery. . Anatomy of the rectum and vagina. bases. dry granulation. . mechanism of drug penetration through skin. Formulation . . .Sonophoresis. Electrically assisted transdermal delivery system (iontophoresis and electroporation). 10. Quality control tests . their merits and demerits. . . 9. manufacturing procedure. semisolid bases and their selection. Dissolution testing. Penetration enhancers. Methods of tablet manufacture. Introduction and anatomy of the skin. physiological and physicochemical considerations. Disintegration testing. Grinding and communition of powders. drug targeting. . Methods of tablet manufacture. Quality control tests for tablets. Suppositories. Ideal requirements. Transdermal delivery system (2CU). Methods of tablet manufacture. Powder flowability studies using angle of repose method. Packaging and storage 1. Definitions. 11. types. 7. Liposomes and other vesicles. 3. 4. Factors affecting drug release from suppositories.

References: 1. 12. Popovich and Ansel (2005). Aulton (2006). testing. Publisher: Thomson Learning. Formulation and characterization of ointments. Publisher: Lippincott Williams and Wilkins. Ed. Publisher: Lippincott Williams and Wilkins.. Remington. Pharmaceutics. 3. 8. 11. Michael E. Quality control tests for tablets (continue). 9. Formulation and characterization of suppositories using the displacement value method. the Science of Dosage Form Design. Formulation of emulsion type (o/w and w/o) ointment bases. Allen. Ansel's Pharmaceutical Dosage Forms and Drug Delivery System. 10. the Science and Practice of Pharmacy (21st edition). 2. Drug release from ointment. Ed. 99 ..

radioimmunoassay. sterile filtration. . Describe the different types of radioisotopes used to make pharmaceuticals. process validation and packaging selection and evaluation. Containers and closures 100 . Pharmaceutics IV Course Code: 1803434 Credit Hours: 2+1 = 3 Academic Level: Fourth. 7. 3. radiation. 6. 9. Apply the various methods of designing drug delivery systems. Parentrals. 2.e. Explain the importance of closures. gaseous. Demonstrations and experiments will provide first- hand experience in the use of equipment and procedures employed to manufacture sterile products. aseptic filling. Types of sterile products . Formulate the various types of sterile products. The course will provide the students with knowledge of the applications of Radiopharmaceuticals. Sterile Products (continue) (2CU). moist heat and dry heat sterilization. Use and explain the terminology in Radiopharmacy i. manufacture and control sterile products. 5. Describe and apply different methods of packaging and labelling of sterile products. first semester. etc. 1. 2. Sterilization techniques. radioimaging. measurement of radioactivity and formulation of radiopharmaceuticals. Define GMP. . Advantages and disadvantages. Explain the use of radiopharmaceuticals in nuclear pharmacy/medicine. . . Apply the guidelines of GMP to improve the quality of pharmaceutical products. quality assurance and quality control 8. dry heat and ethylene oxide sterilization. steam. 4. This course also provides an overview of FDA guidelines and cGMP’s. Design a prototype pharmaceutical industry and standard operating procedures for pharmaceutical industrial processes Description: This course will provide the fundamental principles used to formulate. filtration. Powders for injection. The course imparts to the student the principles of drug development and production and equips the student with basic skills in the good manufacture of pharmaceuticals.(TPN) . Sterile Products (2CU). Objectives: 1. Total parenteral nutrition . Topics to be covered will include formulation criteria. Introduction . primarily injectables. . The course also presents the novel techniques adopted to enhance drug delivery through different delivery systems.

8. . Requirements and manufacturing of: § implants § ophthalmic products. . antioxidants. .Liposomes and nanoparticles drug delivery system. . stabilizers etc. suspending agents. . Added substances (preservatives.Hydrogel based drug delivery system. . Vehicles. Introduction.) 3. 7. Sterile preparation (continue) (2CU). etc. suspending agents. solubilizer. solubilizer. . . . . Measurement of radioactivity. quality control.g autoclave filters. Validation of equipment. Sterile area and its classification. .Ocular drug delivery system. antioxidants. buffers. Sterile preparation (continue) (2CU). . . . Added substances (preservatives.Biodegradable drug delivery system. Formulation. e. Interaction of radiation with biological system. (Laminar flow etc). . Radiopharmaceutics (2CU). stabilizers etc. Advanced drug Delivery System (2CU). . Complete sterility (aseptic area) .) 5. Advanced drug Delivery System (2CU). Pyrogens . . Air control. Quality assurance 4. ophthalmic ointments . Filling/ packaging (plastic and glass containers). Radiopharmacology/therapy 7. .Mucosal drug delivery system. Design of Sterile Area. environmental monitoring methods. .Transdermal drug delivery system. intrauterine drug delivery system.Nasal drug delivery system. 101 . buffers. Sterile preparation (continue) (2CU). Air locks. building and equipment . Validation of filling and packing machines. . . 6.

records and batch. . . GMP and quality control. Ampoule filling. complaints procedures and product recall. contamination. . building and facilities. 9. . packaging material and packing. Role of drug product and drug product quality. Good Manufacture Practice (cGMP) (2CU). . crush glass and ampoules. . glass apparatus. Practical: 1. Quality control tests for glass containers. . metered dose inhalers and dry powder inhalers. In process control. Flow chart for the production of all dosage forms (tablets. Study toure . 11. Master-formula. 3. 14. quality assurance. Documentation: principles. Premises and equipment. training and hygiene. Introduction. Personnel and training: principles. . 13. 2. specification. 6. Drug development and production. Manufacture: principles. validation. Preparation of calcium gluconate injections. . Recovered materials. 12. Good Manufacture Practice (cGMP) (2CU). . Quality control tests for plastic containers for injection. starting and intermediate materials. 102 . storage areas and equipment. . sealing and sterilization. 7. 10. Introduction to FDA’s provisions for cGMP. Quality.Drug delivery to the lungs. principles. Principles. Provisions for GMP.A visit tour to a pharmaceutical manufacture is an integrated part of this course. 4. . Current Good Manufacture Practice (cGMP) (2CU). Quality control tests for rubber closures. . . Good laboratory practices. . . Good Manufacture Practice (cGMP) (2CU). Good Manufacture Practice (GMP) (2CU). 5. Quality control for ampoule sealing.

by Jhon Sharp. Michael E. including in process control and quality control. Sterile Dosage Forms: Their preparation and clinical application. the Science of Dosage Form Design. 1.. sterile products. Pharmaceutics. 2nd edn. Ed. rational and compliance. suppositories. Reference: 1. Pharmaceutical dosage forms: Parenteral medications vol. capsules.. Aulton (2006). 4. 103 . ointments. Ed. suspension). Publisher: Thomson Learning. Salvatore Turco. 1992 2. Dekker. Good pharmaceutical manufacture practice. syrup. emulsion. 3. Publisher:Lippincott Williams and Wilkins.

. 104 . Understand the influence of different physicochemical.pH-partition theory. Drug absorption (2CU). . Biopharmaceutics Course Code: 1803335 Credit Hours: 2+0=2 Academic Level: Third Year. the principles of drug metabolism and elimination. metabolised excreted and factors affecting them. 3.Combined absorption model. degree of ionization. Support the characteristics of various drug delivery systems and their impact on the drug pharmacokinetics.Factors affecting passive diffusion.Vesicular transport. .Facilitated diffusion. 8. . partition coefficient. .Concepts and definitions. 6. Explain how drugs are distributed. . metabolism and excretion) system. . distribution and action of drug from modified release and targeted dosage forms 1. Explain how drug absorption can be optimized. bioavailability and the parameters involved. 2. Description: This course includes the factors influencing the absorption of drugs. drug absorption processes. bioavailability. concentration gradient. bioequivalence. the factors influencing the distribution and disposition of drugs in the body.Fick’s law and pressure diffusion. . Introduction to biopharmaceutics (2CU). 5. 7. distribution. Second Semester Objectives: 1. stability. Design bioavailability and bioequivalent studies.Ion-pair formation. distribution and elimination. . absorption.LADME (liberation. . liberation. Review the role of formulation design in modifying the drug absorption. biopharmaceutics. bioavailability and bioequivalence determination and interpretation will be included The principals of this course underlie the preparation. absorption. pharmacokinetics. Describe the mechanisms and factors involved in drug absorption.Absorption mechanisms . Define biopharmaceutics. 2.Active transport. 4. . physiological and dosage form design on the drug bioavailability.Nature of cell membrane.

. . 7. Dosage form factors influencing drug absorption from the gastrointestinal tract (2CU). Compendial methods of dissolution. Hepatic metabolism. . . . . 105 . Gastric emptying rate. Compendial methods for testing entric-coated products. Intestinal motality.Physicochemical factors affecting drug absorption from GIT. Salt form. Multiple IV bolus dose administration (2CU). Drug accumulation. volume of GIT fluids. . 8. Miscellaneous factors. . viscosity of GI fluids. . . surfactants.Influence of the type of dose form. diluents. Unofficial methods of dissolution testing.Influence of excipients. 6. pH of the gastro intestinal fluid. Solid dispersions. viscosity enhancing agents . 4. . Effect of particle size. Physiological factors influencing drug absorption from gastrointestinal tract (2CU). Multiple dose. degree of agitation. . .3.Factors affecting drug dissolution rate in the GIT. Development of general equation. . . Influence of food and diet. Single dose review . . . Noyes Whitney equation. Surface area of the gastrointestinal absorption sites. . . . Gastrointestinal absorption of drugs (2CU). Physiological factors. .Rate-limiting steps in drug absorption. . Crystal form. Physicochemical factors affecting drug dissolution in the GIT (2CU). Complexation. 5. . Drug stability in the gastrointestinal tract. In-vitro dissolution testing (2CU). . rate of absorption.

C. implants. . pulmonary excretion.). 106 . Pharmaceutics. patches . 3rd edn. Comprehensive pharmacy review. depot injection. Ed. . 13. enzyme kinetics. 11. hepatic clearance. active renal secretion.Hemodialysis. .Targeted delivery systems.g. Drug distribution and protein binding (2CU). L.Transdermal delivery systems. glomerular filtration. 10. Other routes of drug excretion (2CU). permeability of cell and capillary membranes.B.. salivary excretion.Hepatic elimination of drugs.Metabolic reaction. . biliary excretion. . the Science of Dosage Form Design.Renal excretion of drugs. 3. renal disease considerations. water-immscible injection (e. Applied biopharmaceutics and pharmacokinetics (3rd edn. 9. 12. Publisher: Thomson Learning. . Metabolism (2CU). and Yu. Aulton (2006). induction and inhibition. systemic availability. Bioavailability consideration of modified release drug products and targeted drug delivery (2CU). anatomic consideration of the kidney.Drug excretion and biotransformation. . tubular re- absorption. Drug elimination (2CU). diffusion and hydrostatic pressure.g. drug accumulation. A. Shargel. modified release and delayed release . Apparent volume of distribution and plasma drug-protein binding.Factors affecting biotransformation. . Michael E.Intramuscular dosage forms. kinetics of enzyme inhibition. oil). tissue perfusion and initial drug distribution.Subcutaneous dosage forms.Oral dosage forms. . e.. 2. Reference: 1.Physiological factors affecting drug distribution. body fluids. Lippincott Williams and Wilkins. .

Communicate with various audiences by written. V. TPN. semi-solid and liquid preparations (3CU). Become proficient in the expression of quantitative relationships and can perform the needed mathematical operations to infer their consequences. Know and describe the types of communication. Contents: 1. 2. based on physico-chemical principles. 4. 7. cytotoxic dispensing. Order and maintain a supply of drugs. 5. During the laboratory session. admixtures (3CU). 11. Dispensing to ambulatory patients.hypcralimentation. 4. Know and explain the pharmacist-patient communication process. Second Semester. 8. emulsion. Description: This course involves processing a prescription or medication order. Understand and describe the basics of communication 10. clients and others. Define communication and explain the goals. Introduction to institutional practice. development and practice of the patient counseling skills necessary for proper use of the compounded product. ear drops). suspension. medication administration records (3CU). 3. semi-sterile dispensing (eye drops. the preparation and dispensing of pharmaceutical solution. 9. Dispensing of radio pharmaceuticals (3CU). Problems associated with extemporaneously prepared formulae (3CU). 6. 5. Aseptic Dispensing (continue) (3CU). including order processing. 7. medication administration records (3 CU). 13. Provide information to the prescribers. Define the fidelity of communication and factors affecting it. 3. including order processing. verbal and electronic media for a variety of purposes 12. distribution of control 107 . emphasis will be placed on the selection of proper excipients. 8. purity and strength of medications. Keep comprehensive records of all medications dispensed in order to satisfy the provision of law. Dispensing of I. 2. 6. Determine the identity. semi-solid and solid dosage forms and development and practice of the patient counseling skills necessary for proper use of the compounded product. Extemporaneous dispensing of some formulations. Dispensing of Medications Course Code: 1803436 Credit Hours: 3+1=4 Academic Level: Third Year. solid. Introduction to institutional practice. Weigh. for use in the extemporaneous compounding preparation. measure and mix drugs and other medicinal compounds. The course also provides the students with knowledge on the communication process and skills to enable them to communicate effectively. chemicals and pharmaceutical stock. Objectives: 1.

9. aromatic waters. 12. Collett and M. 5.. Publisher: Churchel Livingstone. Martindale: The complete drug reference. 11. 10. S. Patient education and counseling (3CU). C. substances. Basics of patient-pharmacist communication: process models. mixtures. Patient assessment (3CU). the Pharma cycentral sterile supply room (3CU). 2. The Pharmaceutical Press. Definitions and background of community pharmacy (3CU).. Communication skills for pharmacist.. Kathleen Parfitt. Pharmaceutical Practice. . ed. spirits and ear drops as well as practical simulation of how to dispense drug product to the patient. London. Pharmaceutical Codex.Aulton. emphasis will be placed on the selection of proper excipients. UK. Sweetman. 108 . 6. types. Role of pharmacist as Public Health Educator in the community for drug monitoring and drug information (3CU). fidelity. elixirs. The United States Pharmacopoeia (USP) and National Formulary (NF) 3. for use in the extemporaneous compounding preparation. based on physico-chemical principles. manufacturing bulk and sterile. skills. Ed. listening and meaning and communications (3CU). The British Pharmacopoeia 4. Diane M. 14. Gargles. Non-verbal communication (3CU).E. Practical: -The practical course will focus on Compounding of selected examples of: solutions.During the laboratory session. 13. dispensing during off-hours. Reference: 1. linctuses.

Contents: 1. Industrial Pharmacy Course Code: Credit Hours: 3+0 = 3 Academic Level: Fifth. nature and properties of important materials employed in construction and erection of plant. Understand the concepts of pharmaceutical operations. Objectives: 1. . . Outline the design and mechanism of action of the instruments included in the unite operation in pharmaceutical practice. semi finished and finished product. 2. 3. .Tubular heaters.Classification of heat flow process. . inductive heating. 8. 109 . conduction. Review the use and application of each operation in relation to its advantages. tablets. Description: An introduction to basic engineering principles that are involved in the commercial manufacture of pharmaceutical dosage forms. Flow of heat (3CU). convection and radiation. . disadvantages and mechanism of action. 4. Predict the relationship between the equipment design and product characteristics. 7. . first semester. 2.Overall coefficient of heat transfer. 9. 10. Diagrammatically design the studied equipments for each operation.Steam as a heating medium. capsules and other dosage forms. 6. 3. . . Rationalize the use of the equipment for a specific application in pharmaceutical industry. Explain and discuss the use of different equipment to achieve certain operation in pharmaceutical industry. convenience and storage of raw materials.Mechanisms of heat transfer. mixing.Tubular heaters. heat interchangers. disadvantages and mechanism of action. heat transfer by radiation and convection. Pharmaceutical Lay Out and Plant Designing (3CU). Discussions will focus on the design and operation of equipment used for each unite operation in the factory. Heat transfer (3CU).General layout and plant designing of the Pharmaceutical Industry Pharmaceutical plant construction. Point out the principles of each unite operation in pharmaceutical processes.Design of heating equipment. and how such principles as blending. Define the physical principle of each unite operation in industrial pharmacy. Support the equipment used for each unite operation in relation to its advantages. heat and mass transfer are utilized to design and specify equipment used in producing powders. 5.

.Standard screens. semi- continuous centrifuge.Classification of dryers . ..Darcy’s equation. Mixing (1CU). freeze dryers. continuous conical centrifuge.Dryers for solid materials.Convectional and conduction dryers. jacketed kettles. fluid energy mill.g. Centrifugal filtration (3CU).Pharmaceutical applications. Size separation (3CU).Filter aids.Oscillating tray sitter grating sifters. . extruder. . . .Evaporation under reduced pressure. plate and frame filter. 6. 5. 7. . . . Size reduction (communition) (3CU). 10.Factors influencing size reduction. colloid mill.Multiple effect evaporation. . 110 .Reasons for size enlargement.).General principals of evaporation.Handling of powders. roller mill. . high speed mixer granulator. equilibrium moisture content. . .Methods and mechanisms of granule formation. Drying (3CU). cyclone separators. hammer mill. . . forced circulation evaporators and evaporator accessories. . oscillating granulator.Principles of freeze drying.Sedimentation and elutriation. . . 8. 11.Classification of filtration filters (e. .Theory and reasons of size reduction . e.Energy requirments . .g. rotary filter….Large scale equipment. Evaporation (3CU).Laboratory equipment.4. filter press. . tube evaporators.Types of evaporators. 9. . . Filtration (3CU). . leaf filter. ball mill.Theoretical consideration. .dryers for dilute solutions and suspensions.Theory of filtration and filtration media.Pharmaceutical granulation equipments. .Mechanisms and equipments used for size reduction.Theory of drying loss on drying and moisture content. Size enlargement (2CU).

15. stability.Mixing equipments used in liquid/liquid. Distillation (3CU). Study tour. 13. 111 .Rowlin. 12. Bentley's TextBook of Pharmaceutics . Tutorial Pharmacy . material and energy balances.critical humidity prevention of caking.Classification. packaging area.Cooper and Gunn. 4. . 2. steam. An introduction to Chemical Engineering .Lieberman and Kanig. Influence of packaging materials. A visit to pharmaceutical industries will be an integrated part of the syllabi. . . (b) binary mixtures of immiscible liquids. Theory and Practice of Industrial Pharmacy-Lachman. batch crystallizers.Nucleation and crystal growth .Industrial equipment for vacuum. . packaging equipment.Fundamentals and mechanism. 14. packaging lines. 3. liquid/solid and solid/solid mixing. (c) Rectification rectifying columns fractionating column and simple calculations. Crystallization (3CU).Theory of distillation of mixtures (a) binary mixtures of miscible liquids. Packaging Technology (2CU).Badger and Banchero. . References: 1. simple vacuum crystallizers. . reflux and molecular distillation.

Umm Al-Qura University Faculty of Pharmacy Department of Clinical Pharmacy Modules 2008 112 .

5. and uses (as slings. Description: This course is structured to provide the necessary knowledge and hands-on experience on Standard First Aid and CPR. Primary survey. tying. Aware of first aid guidelines and "good practices" 2. First Aid. Lift.immobilization 11.various parts of body. Fractures in specific sites .direct and indirect pressure 6. First aid to chest injury. ring pad and slings for wounds and bleeding 7. 14. Principles of lifting and carrying 12. Fifth Edition. Heimlich maneuver (abdominal thrust) for choking casualty. Fracture or dislocation. restoration of circulation and respiration. American Academy of Orthopaedic Surgeons (AAOS). folding. Second Semester Objectives: 1. Secondary survey. ring pads and slings for fractures 8. Recovery position (14 CU): 2. Shock from blood and fluid loss . First aid Course Code: 1804551 Credit Hours: 0+1=1 Academic Level: Fifth Year. 2. By American National Red Cross. Bandaging of wounds . Use of triangular bandages. References: 1. First aid to abdomen injury 10. Unconscious casualty. American Red Cross First Aid Textbook. 9. CPR. Conscious casualty 13. Rescue breathing for non breathing casualty 4. Use of triangular bandage . 3. ring pad and pressure pad) 3. The first aid care includes prevention of further injury. It deals with general rules applied in conditions where first aid is required. Able to properly treat injuries and respond to emergencies. Be a part of health care providers team. splint. Use of bandage as pressure pad. and AED (Academic Version). First aid to scalp and face wounds. cut in the palm.first aid treatment. 113 . Arrest of bleeding . carry and move casualty. CPR technique for one-man and two men first aider. Burns. storing.introduction to bandaging. controlling of bleeding and removing of poisons Contents 1.

Evaluate sources of online drug information 3. Common Statistical Tests. It uses examples to help students learn to use the Internet to obtain drug information and determine the strengths and weaknesses of various types of drug information. Principles of Drug Information Course Code: 1804452 Credit Hours: 1 + 0 =1 Academic Level: Forth Year. 2. Biostatistics: Interpretation of Data. Contents 1. Patient Case Presentations 9. Understand the necessity of a basic knowledge of biostatistics in the provision of pharmaceutical care 5. Appropriately incorporate the information gained from the report into your clinical practice Description: This course is designed to help students understand the types of drug information available and what sources of information are appropriate to use in a variety of situations. References: 1. 114 . Advice for the Patient: Drug Information in Lay Language (Usp Di Vol II: Advice for the Patient) by Pdr Staff. Patient Education/Counseling 11. Understand the rationale for the use of each statistical test used in the study 8. 3. Micromedex. Professional team interaction 14. null and alternate hypotheses 7. 2000. Evaluate and interpret the statistical and clinical (non-) significance of the results that are reported 9. Evaluation of Medical Literature 5. The biostatistics teach students to evaluate studies based upon the quality of the data reported and not solely on the opinion of the researchers. Untangling the Web: A Primer on Using the Internet for Drug Information 3. Drug therapy evaluation and development 8. ADR Reporting and Monitoring 4. Formal Written Presentations 13. Locate drug information using a personal computer with internet access 2. Introduction to Drug Information (14 CU): 2. First Semester Objectives: 1. The Use of Computers in General Practice. Full text drug information databases. Drug distribution systems 6. Basic Statistical Concepts. By John Preece. Formal Oral Presentations 12. Identify the purpose of the study. Perform the following when evaluating a research report in the medical literature 6. Monitoring for Endpoints 10. Disease State Knowledge 7. Understand the different sources and types of drug information and determine the place each hold in drug information 4.

plasma and urine objectives: i. the student will calculate the slope and intercept by hand as well as using linear regression. 2. The student shall define all pharmacokinetic parameters discussed in each lesson. time(T)) 3. IV one compartment model. ka . iv. Given patient drug concentration and/or amount v. iii. Oral one compartment model objectives: i. Clearance. Clearance. i. the student shall state the assumptions of the model used to develop the theory used to describe the profile. Given patient drug concentration and/or amount v. kr . the student will properly construct various graphs of the data. ii. response (R) v. The student shall demonstrate the proper calculus procedures of integration and differentiation. concentration (C) 2. Pharmacological Response objectives: i. response (R) v. Given various graphical representations of data. AUC. The student shall define all pharmacokinetic parameters discussed in each lesson. Given a pharmacokinetic profile. K. First Semester. 115 . the student will be able to properly construct a graph and compute the slope. Given a literature article. AUC. time (T) ii. the student will evaluate it with respect to the tools learned. 3. Objectives: 1. Basic Mathematical skills objectives: . the student will be able to compute the slope of the third. time profiles. Given any two of the above data sets. the student will evaluate it with respect to the tools learned. the student will calculate the relevant pharmacokinetic parameters available (Vd . Given a literature article. concentration (C) v. The student shall demonstrate the proper procedures of mathematical and algebraic manipulations. iii. Given patient data of the following types. Basic Pharmacokinetics Course Code: 1804353 Credit Hours: 2+0=2 Academic Level: Third Year. ii. km . the student will evaluate it with respect to the tools learned. Time profiles. MRT) from IV data. Given a pharmacokinetic profile. the student shall state the assumptions of the model used to develop the theory used to describe the profile. MAT) available from oral data. kr . 4. Given a literature article. MRT. iii. km . iv. the student shall demonstrate the relationship between the model and the ADME processes. Given a pharmacokinetic profile. K. ii. iii. v.Given a data set containing a pair of variables. 1. the student will calculate the relevant pharmacokinetic parameters (Vd .

The student shall define all pharmacokinetic parameters discussed in each lesson. the student will evaluate it with respect to the tools learned. the student will estimate the bioavailability (compare AUCs) and judge professional acceptance of the product with regard to bioequivalence (evaluate AUC. ii. the student will evaluate it with respect to the tools learned. The pharmacist is the only health professional extensively educated in 116 . Multiple dosing objective: i. and physicochemical factors which influence the transfer processes of drugs in the body thus influence the rate and extent of ADME of those drugs in the body. The biological. pharmacological and toxicological actions are related to plasma concentration of drugs. the student shall state the assumptions of the model used to develop the theory used to describe the profile. Tp and Cpmax ). Modification of the dosing regimen. the pharmacist will be able to individualize therapy for the patient. 7. physiological. Given patient information regarding organ function. Bioavailability objectives: i. v. optimal drug therapy. preventing toxicity and assuring maintenance of therapeutic concentrations of active ingredient. iii. the student will devise and justify (VI) the optimal dosage regimen for the compromised patient. the patient will justify dosage regimen recommendations. Given a pharmacokinetic profile. In many cases. which consists of the dose and the dosing interval. and Excretion (ADME) of drugs in the body. ii. Clearance objectives: i. Given patient information regarding organ function. ii. 6. Given a literature article. Given population average patient data. the student will devise and justify (VI) dosage regimen recommendations for the compromised patient v. iv. using patient specific parameters. iv. the student shall state the assumptions of the model used to develop the theory used to describe the profile. Description: Pharmacokinetics is the mathematics of the time course of Absorption. The student shall define all pharmacokinetic parameters discussed in each lesson. Given patient information regarding organ function. Metabolism. iii. the student will devise dosage regimens which will maintain plasma concentrations of drug within the therapeutic range. Given a pharmacokinetic profile. Pharmacokinetics is a necessary step toward rational. Consequently. Distribution. is the method of dosing optimization. 5. Given sufficient data to compare an oral product with another oral product or an IV product. the student will calculate changes in clearance and other pharmacokinetic parameters inherent in compromised patients. Given specific patient information. Given a literature article. through the study of pharmacokinetics.

at any time after discontinuation of infusion.MRT using infusion data 2.Define PK parameters used in bioavailability studies 2.Calculate dose for desired Cpss 5. Define & calculate AUC 7. Calculate conc. Define & calculate CL 9. Calculate Km 13. Calculate CL from oral data 8. Calculate Kr 12. Estimate bioavailability using bioequivalence 117 . The profession of Pharmacy has determined that there are minimum entry level abilities necessary for a pharmacist. Relationship between model and ADME 3. Calculate time to reach steady state 6. Calculate infusion rate for desired steady state.Km.AUC.Utilize rate Vs time to calculate K and Vd 3. CL. Define & calculate Vd 4. the area of pharmacokinetics.Calculate AUC from oral data 7. Estimate absolute Bioavailability 4.Calculate Km from oral data 5. Calculate% metabolism /excretion • IV Infusion dosing one Compartment: 1. Calculate MRT from oral data • Bioavailability: 1.Calculate:Vd.Demonstrate proper procedures of math and algebraic manipulations 3 Demonstrate proper calculus • Pharmacological Response: 1.Calculate Ka from oral data (plasma) 2. Contents: • Basic Math Skill: 1. at end of infusion 7. Describe PK model 2.Calculate Kr from oral data(urine) 4. Calculate Vd from oral data 6.Calculate conc. Computing slope of third when given two other slopes • IV bolus dosing one compartment Model (Plasma and urine) for Parent drug and metabolite: 1. This course deals with a specific subset of those competency statements. Define & calculate t1/2 6. Response Vs Concentration 2. Given Patient data calculate above PK parameters 10. 4. • Oral one compartment model: 1. Define & calculate K 5.t1/2.Calculate slope & intercept 2. Calculate K from oral data(plasma) 3.Kr. Concentration Vs Time 4. Calculate K 11. Response Vs Time 3. Describe PK model that describe profile 3. Define & calculate MRT 8.

Define and show relationship to ADME 2. Ndemo. Yu.Describe PK model used to describe profile (model- dependent approach to estimating CL) 3. Kearns. Applied Biopharmaceutics and Pharmacokinetics.Show how creatinine clearance is related to organ clearance 5. Determine change in clearance due to change in rate of blood flow.Introduction to Therapeutic Drug Monitoring(TDM) 2.C. 3. 1999. Modifying dose based altered protein binding 10. New York. Wolfgang A. 118 . Notari.Dtermining Cpmin 3. 4.Detemining Cpmax . • Clearance: 1.Modifying dose based on altered CL 7.Determining the dosing interval 6. Estimate clearance of an organ based on dose. MR PharmS. Making the connections. and fraction eliminated by organ 7. PharmD.Determine change in CL due to functional changes in an organ 8. 3.Devise and justify dosages for given organ functions 10 Devise and justify dosages for given organ functions • Multiple dosing: 1. Biopharmaceutics and Clinical Pharmacokinetics. Fourth Edition. 9. Devise and justify dosage regimen for given altered organ function • Application: Problems based application of pharmacokinetics References: 1. by Robert E.Determining Cp avg 4. Estimate total clearance based on dose and AUC 6. 2. Basic Pharmacokinetics.Modifying dose based on altered K 8. Ritschel and Gregory L.Modifying dose based on altered Vd 9. Devise and justify dosage regimen for given altered organ function 11. An Introduction. Handbook of Basic Pharmacokinetics. Leon Shargel and Andrew B.State importance of CL to clinical practice 4.Modifying dose using bioavailability and salt factors 5. AUC. Francis A. Marcel Dekker Inc.

Initiate drug dosing regimens individualized to specific patient demographics and organ function. 8. pharmacokinetic considerations with other anti- infectives 7. Ethosuximide and Lithium 14. prepare student to utilize pharmacokinetic data generated from individual patients to develop appropriate therapeutic dosing regimens. Heparin and Warfarin References: 1. Clinical Pharmacokinetics Course Code: 1804454 Credit Hours: 0+1=1 Academic Level: Forth Year. 6. Disease states and variability in pharmacokinetics. Calculate appropriate dosing regimens utilizing derived pharmacokinetic parameters. Interpret drug serum concentration data. Physiological states (28 CU): and variability in pharmacokinetics. 4. Valproate. Assessing renal and hepatic function. 2. 3. Lidocaine and Flecainide 11. Phenytoin 12. 2. 3. Published by: Lippincott Williams & Wilkins 2. Calculate individual pharmacokinetic parameters. It provides the student with the principles for dosing patients more rationally and safely Contents 1. Winters. 6.This course is designed to enable the student to understand how various disease states alter the pharmacokinetic parameters. 3. Prepare student to recognize sources of individual pharmacokinetic variability due to physiological and disease factors 7. Michael E. 5. Tozer. Procainamide and Quinidine 10. Review of basic pharmacokinetic principles. basic clinical pharmacokinetics. Prepare student to understand the application and role of pharmacokinetic information generated for selected drugs and drug classes. Malcolm Rowland & Thomas N. Lea & Febiger Philadelphia. Clinical Pharmacokinetics Concepts and Applications. Clinical pharmacokinetics of renally cleared drugs and mixed renal and hepatic clearance drugs. 5. 119 . Clinical pharmacokinetics of low and high extraction ratio drugs. Schentag and William Jusko (eds) Applied Pharmacokinetics. Theophylline 8. William E. Digoxin 9. 4. Through exposure to case studies. Applied problems (Aminoglycoside antibiotics and vancomycin). Phenobarbital and Carbamazepine 13. Demonstrate an understanding of the appropriate application and limitations of select pharmacokinetic models. Jerome J. Cyclosporine. Description: . First Semester Objectives: 1. Evans.

making a difference to the patient. Have direct involvement in patient care. chemotherapy and complex intravenous medicines (2 CU).a whole variety of medical and surgical specialties. influencing treatment choices by being involved in decision making at the point of prescribing. Recognize of expertise in whatever specialty the pharmacist choose. development. so a period in a community pharmacy will be part of the pharmacist’s training programme (2 CU). Be a part of a number of teams. pharmacists and pharmacy services are highly valued by colleagues and management 7. residential and nursing homes (2 CU). a sense of contribution 2. acknowledgement of your achievements. organizational structuring and administration of pharmaceutical services within an institutional setting are presented in a combined lecture and practical simulation laboratory format. observe. from general acute medicine to psychiatry. The planning.screening prescriptions for appropriateness and accuracy prior to dispensing (4 CU) 6. enabling the pharmacist to formulate the pharmacist own preferred practice 5. and work with. Clinical pharmacy . participation in ward rounds. counseling patients (4 CU). 4. extensive social and professional networks in the pharmacy and throughout the hospital 3. 6. Continue professional and career development Description: This course provides the student with an overview of certain aspects of hospital /institutional pharmacy service. influencing treatment decisions. Have a clearly defined career structure with opportunities to develop in a range of skills which may include technical.the RSPGB will require the pharmacist to have an awareness of community pharmacy practice. 5. Medicines information . Hospital Pharmacy Course Code: 1804555 Credit Hours: 2+0=2 Academic Level: Fifth Year. Community services pharmacy . several pharmacists rather than just one role model. Support from fellow pharmacists and colleagues is always available 4. Have the opportunity to get input from. Community pharmacy . clinical. Dispensary . Aseptic/technical services . Involvement with community clinics. 120 . First Semester Objectives: 1.working at the interface between primary and secondary care. Contents 1. 3. education or management positions.answering enquiries from a wide range of healthcare professionals and patients about their medicines (4 CU). Activities include taking drug histories. optimizing medicines management and monitoring outcomes. 2.commonly involved in the dispensing (28 CU): of parenteral nutrition.

Quality assurance/quality control . References: 1. and other people (2 CU). Durgin. 2. 8. Procurement and distribution . 121 .specialist areas. a project. 10. v By Zachary J. Management . Radiopharmacy and clinical trials . Pharmacy Practice for Technicians.developing an understanding of how medicines are purchased and stock is managed in the most cost effective way (4 CU). John O'Grady.the basics of managing the pharmacist. 7. his time. The Textbook of Pharmaceutical Medicine.making sure that products and services reach the required standards (2 CU). By John Parry Griffin. 9. Hannan. available in some hospitals (2 CU). Jane M.

Antibiotic Overview 11. Explain the rationale for the use of certain drugs in the therapy of a given disease 3. Clinical Significance of Variations in Drug Metabolism and Interactions 10. interactive Internet-based lectures and case studies. Identify potential drug interactions and recommend appropriate action 8. The class format includes online reading assignments. Identify important pharmacokinetic parameters that may affect drug dosing or monitoring 6. Myocardial Infarction 4. Discuss the pathophysiology of the disease states presented 2. Myocardial Infarct. Alzheimer's Disease. Emphasis will be placed on the integration of pathophysiology. Variations in Drug Metabolism & Interactions. Ischemic Heart Disease. Laboratory Tests. and assignments. Ischemic Heart Disease 3. and Depression. Therapeutics I Course Code: 1804556 Credit Hours: 2 + 1 =3 Academic Level: Fifth. Identify parameters that should be monitored for efficacy and safety 7. expected outcomes of drug therapy. clinically important drug-drug or drug- disease interactions. Upper GI Disorders. Stroke. Identify factors that may affect drug selection in a specific patient with multiple diseases and medications 4. study guides. and Renal Disease. Recommend an appropriate drug and dosing regimen for a particular disease 5. key monitoring parameters. Heart Failure 5. first semester Objectives: 1. Antibiotic Overview. Heart Failure. Identify potential compliance problems and recommend appropriate actions Description: This course focuses on the pharmacotherapy and the role of the pharmacist in disease state management of Hypertension. pharmacology and therapeutics to devise appropriate pharmacy care plans. Seizure Disorders. Renal Function and Disease 8. These plans will include rationale for drug use. Hypertension 2. Identify factors that should be included in patient counseling for a specific drug 10. Identify potential drug-induced adverse effects or toxicities and recommend appropriate actions 9. Peptic Ulcer Disease 7. Asthma and COPD 9. Alzheimer's Disease Pathology 122 . Infectious Diseases. Contents: 1. Asthma & COPD. Thrombosis and Stroke 6. counseling and compliance issues. selection and dosing regimens. Anticoagulation. Parkinson's Disease.

: Pharmacology. 4. Prentice Hall. Williams and Wilkins. and Michael Posey. The clinical Use of Drugs. 6. fifth edition. Appleton and Lange: Norwalk. Goodman and Gilman´s The Pharmacological Basis of Therapeutics. Katzung : Basic and Clinical Pharmacology.P. B. Ed. Dale M. Applied Therapeutics. Dipiro. Coda Kimble. 12. latest edition. Joseph T. Rang H. Herfindal Eric and et al. Clinical Pharmacy and therapeutics. Pergamon Press. 123 . Seizure Disorders 14. Robert L. 2. Treatment and Parkinson's Disease 13. Churchill Livingstone. Pharmacotherapy: A Pathophysiologic Approach.M. Connecticut.. Lippincott. Talbert. Textbook of Therapeutics: Drug and Disease Management. 5. 7. Inc. Lippincott Williams and Wilkins. Alfred Goodman Gilman. Ed. Marry Anne. Depression References: 1.. 3.

The class format includes online reading assignments. Osteoporosis. Recommend an appropriate drug and dosing regimen for a particular disease 6. Apply disease and drug knowledge to the design and monitoring of therapeutic treatment plans for patients Description: This course focuses on the pharmacotherapy and the role of the pharmacist in disease state management of diseases and conditions including Hormone Replacement. Identify potential compliance problems and recommend appropriate actions 12. Therapeutic II Course Code: PHCP 703 Credit Hours: 2+1=3 Academic Level: Fifth. These plans will include rationale for drug use. Identify factors that should be included in patient counseling for a specific drug 11. second semester Objectives: 2. study guides. key monitoring parameters. Rheumatoid and Osteoarthritis. counseling and compliance issues. Hormone Replacement Therapy 2. Understand how drug therapy is used to treat or prevent diseases 13. Identify potential drug interactions and recommend appropriate action 9. Lipid Disorders 5. Contents: 1. expected outcomes of drug therapy. Identify important pharmacokinetic parameters that may affect drug dosing or monitoring 7. and assignments. Solid Tumor Diseases 124 . Rheumatoid and Osteoarthritis 4. interactive Internet-based lectures and case studies. selection and dosing regimens. Critical Care and Infectious Diseases. Lipid Disorders and Diabetes. Diabetes Treatment 8. Understand pathophysiology of disease states discussed in the modules 3. Osteoporosis 3. clinically important drug-drug or drug-disease interactions. Emphasis will be placed on the integration of pathophysiology. Cancer Principles and Oncology Supportive Care 9. Coagulation Disorders 6. Identify parameters that should be monitored for efficacy and safety 8. Identify potential drug-induced adverse effects or toxicities and recommend appropriate actions 10. Explain the rationale for the use of certain drugs in the therapy of a given disease 4. Identify factors that may affect drug selection in a specific patient with multiple diseases and medications 5. pharmacology and therapeutics to devise appropriate pharmacy care plans. Cancer. Diabetes Disease State (Type I and II) 7.

: Pharmacology. Lippincott Williams and Wilkins. 6. Pharmacotherapy: A Pathophysiologic Approach. Respiratory Tract Infections 13. Robert L. Lippincott. B.P. Ed. Utilization of Hemodynamic Monitoring/Shock 14. Hematological Malignancies 11. Katzung : Basic and Clinical Pharmacology. Dale M. Applied Therapeutics. Ed. Textbook of Therapeutics: Drug and Disease Management. 3. Churchill Livingstone. Management of Shock/Vasoactive Pharmacotherapy References: 1. Talbert. and Michael Posey..M. Williams and Wilkins. Herfindal Eric and et al. Marry Anne. 2. Goodman and Gilman´s The Pharmacological Basis of Therapeutics. 4. Coda Kimble. 10. The clinical Use of Drugs. Alfred Goodman Gilman. Prentice Hall. 125 . fifth edition. latest edition. Valvular Heart Disease 12. Rang H. Clinical Pharmacy and therapeutics. Appleton and Lange: Norwalk. Pergamon Press. 7. Joseph T. Inc. 5. Dipiro.. Connecticut.

Environmental scanning and policy development 5. income distribution and taxis are introduced. store and dispense drugs. 10.) . household behavior and consumer choice. scheduling and critical path analysis 8. Create and develop a highly effective working environment. Acquire marketing management skills. Project management (cont.) . Project management . coordination and leadership skills. management and evaluation are also studied. 5. Project management (cont.) .economics: . household behavior and consumer choice 3. technical and scientific methods . Know the concept.Function of management 6. Project planning.Theoretical framework and policies 2. 11. Economic principles (cont. Apply different techniques to measure income growth.Progress assessment and project evaluation 126 . Project management (cont.Quality control. Think analytically about the problems facing a developing project. Contents: 1. 9. 8. Face the challenges present in the misuse of medicines. Project management (cont. communication. 12. distribution and other related concepts.Team building and problem solving 9. Create and implement a strategic plan. Second Semester Objectives: 1. Economic principles including supply and demand.Control.): . forming. 3. Social responsibility and business ethics will be covered. The course will also focus on developing an analytical framework for planning. progress assessment.Definition.) . Description: The course is designed to introduce students to the principles of micro- economics including its theoretical framework and policies designed to stimulate it.project life cycle 7. Project planning . Principles of micro. Know how to buy. nature. 7. Economic principles: . competition policy and regulation.Competition policy and regulation. scope and importance . Pharmacy Administration Course Code: 1804558 Credit Hours: 2+0=2 Academic Level: Fifth Year. 2. 4.Supply and demand. Acquire motivation.) . Effectively manage conflict situations in the workplace. solving problems. importance and function of management. Project management (cont. Make decisions based on ethical standards. 6.Behavioral effects on control 10. Develop and implement a work unit supported by certain objectives. income distribution and taxis 4. managing and evaluating processes.

communication. Management process . 1995 127 . Ed. UNIX System Administration Handbook. Production management .. Management process .Social responsibility and business ethics References: 1. Prentice Hall. Evi Nemeth.Marketing and financial management 12. coordination and leadership 13. 11. 2nd.Public relation management 14. 2nd. Management process .Motivation. 2. et al. 1995. Essential System Administration. Ed. By AEleen Frisch O'Reilly.

7.etc. Opportunities for case discussions and problem solving will be integrated throughout the course.Adulteration. Discuss legal issues with ethical implications. unlicensed medicines . Discuss appropriate risk management strategies for pharmacy practice. …………. 7. Know the Saudi regulation of pharmacy practice. Controlled drugs and their subclasses . 9. production and marketing. Discuss the legal and ethical responsibilities of pharmacists.Anxiolytics. 8. Ethical principles that correlate between the rights of patient and pharmacist duties will be presented. Explain the concepts of duties. device. a physician and employer may have of a pharmacist. 2.Definitions (drug. Prescription exemption 8. 3.) 4. The laws relate to subset of drugs that have the potential for abuse. The course also focuses on how far the government and licensed health care professionals should go to protect people from the consequences of their own risky choices in drug use. Description: The main task of pharmacy law and ethics is to provide the practicing pharmacist with advanced knowledge about the legal and ethical basis of pharmacy practice.. Contents: 1.etc. drug and cosmetics acts: .. tranquilizers and hypnotics 9. This course emphasizes the pharmacist’s responsibility to care for patients and to respect patients as autonomous individuals. misbranding.classification of medicines 6. The Saudi food.The history of pharmacy law 3. and these laws seek to restrict their inappropriate use are studied. Describe Saudi regulation of medication dispensing and distribution. dispensing and Distribution. Sale and supply of medicines: . obligations and rights. Licensing of medicines and consumer protection: . Explain the rules relating to controlled substances prescribing.The purpose and the structure of pharmacy law 2. List the reasonable expectations that a patient. The basis of pharmacy law (cont. Controlled drugs and their subclasses (cont. Know the Saudi pharmacy law and legal systems of medication development.) 128 . Basic illegal acts: .Product liability. Pharmacy Law and Ethics Course Code: 1804459 Credit Hours: 1+0=1 Academic Level: Forth Year. label. 4. The basis of pharmacy law: . …………. First Semester Objectives: 1. 5. 10. cosmetic.evaluation and management of risk and provision of advice 5. 6. Discuss special legal requirements for industrial pharmacy practice.): .

obligations and rights. Codes. standards and systems of governance and practice: . Duties. Duty of care to patient and application of professional ethics 11. values in pharmacy 12. 14.E. Political and legal framework. G.R. Applebe (Author). Dale and Applebe's Pharmacy Law and Ethics (Paperback) by J. Editor) 2.Narcotics 10. . Joy Wingfield (Author. requirements and processes relevant to pharmacy References: 1. The pharmacy law and ethics in Saudi Arabia Kingdom 129 .Risk management and personal accountability 13. Dale (Author).

Umm Al-Qura University Faculty of Pharmacy Department of Pharmaceutical Chemistry Modules 2008 130 .

alkenes.Nomenclature.Alkanenitriles . . 7. 8. Relate physical and chemical properties to structure. … etc. saturated hydrocarbons.) .Definition . properties. synthesis. amides.Classification 9. carbonyl compounds. preparations and reactions. 5. Carbonyl compounds (cont.Dibasic acids 8. alcohols. alkynes. chemical structure. properties. preparations and reactions. Carboxylic acids derivatives (cont. Unsaturated hydrocarbons (Alkenes and alkynes). reactions. 4. amines.) . nomenclature. The study will also include stereo-chemistry. esters. reactions. preparations.Nomenclature. Know the basics of organic chemistry. Organohalogen (alkyl halides. Pharmaceutical Organic Chemistry I Course Code: 1805221 Credit Hours: 2 + 1 =3 Academic Level: Second Year. Polymers . Develop mechanistic understanding of some organic reactions 6. Understand stereoisomerism and solve stereochemical problems.Alkanoic acids and amino acids. Stereochemistry . 3. Carboxylic acids and derivatives . properties. Selected examples aliphatic organic compounds of medicinal or pharmaceutical use will be discussed. tautomerism. nomenclature . classification. ethers. Identify aliphatic organic compounds from their physical and chemical properties (reactions of functional groups).) and Amines . Description: The course focuses on the basics of organic chemistry.different organic classes. optical activity and Chirality. Define the chemical structure of different aliphatic organic compounds. Ethers and Carbonyl compounds (Aldehydes & Ketones) . reactions of aliphatic organic compounds containing various functional groups (alkanes.Acyl halides and carboxylic acid anhydrides 6.Nomenclature.Nomenclature.). 2. Solve organic problems and synthesize selected organic compounds from their simple precursors. carbohydrates.Esters . carboxylic acids.Amides and lactams 7. 3. Carboxylic acids (cont. Alcohols. 131 . First Semester Objectives: 1. preparations. 2. 5. bonding. unsaturated halogen compounds) and Organometalic compounds . Acquire the essential safety rules of the handling and dealing with chemicals. Introduction. 4.Isomers. properties. Contents: 1. Classification: .

Organic Chemistry Structure and Function. John McMurry Brooks.General and special tests 6. Di. Neil E. 5th Ed.) . Carbohydrates (cont. Alcohols .. Aldehydes and Ketones .Physical characteristics 2.Lassaigne test. . 10.) . Vollhardt. Scheme of identification . 4th Ed. compounds . Carboxylic acids . Freeman & company.Organic Chemistry. safety measures and glassware.(2000). Oxford.. Carbohydrates (cont) .General and special tests 11.Organic Chemistry. Introduction and Scheme of identification . Carbohydrates . Fatty acids and Esters .Racemic mixtures 11.H. Salts of carboxylic acids (cont.. 132 .Melting and boiling points 5. (2002). 4. New York. Stereochemistry (cont. Detection of elements in org. (2002). Oxford University Press.USA.General and special tests 13. 4th Ed.The cyclohexane ring 12.General and special tests References: 1. . Pierre Lazlo. Peter C.) -Structurally modified carbohydrates.General and special tests 7. Salts of carboxylic acids . W.General and special tests 8. (1995). G.General and special tests 10. USA.Organic Reactions Simplicity and Logic.Cyclic structure of monosaccharides 14. Carbohydrates . Cole Thomson Learning.) . Carbohydrates (cont.Sequence rules. 4. 3.) . Physical constants .CA. K.General and special tests 12. Marc London. Stereochemistry (cont.and polysaccarides Practical: 1. Schore. 2. UK. John Wiley & Sons.General and special tests 9.General and special tests 14. Acid anhydrides and Acid chlorides .Laboratory instructions.Monosaccharides: Synthesis and reactions 13. Amides and Amino acids .Chemical characteristics 3.

synthesis. Heterocyclic compounds (Six –membered derivatives) .Naphthalene. reactions of some aromatic organic compounds containing various functional groups (benzenoid compounds. NMR and MS) in the identification of organic compounds will be included. Halogenation. .).Acridine. 5.derivatives and aromatic amines.Nomenclature . Aromatic.). 5.Nitration. Identify aromatic organic compounds from their physical and chemical properties (reactions of functional groups).Aromatic carboxylic acids. the diazines 11. sulpho. 4. Quinoline and isoquinoline 10. Pharmaceutical Organic Chemistry II Course Code: 1805222 Credit Hours: 2 + 1 =3 Academic Level: Second Year. . substitution reactions and mechanisms . Reactivity and orientation of substituted benzenes . Reactivity and orientation of substituted benzenes(cont. Phenols. Contents: 1. 9.Arenes. Heterocyclic compounds (Five –membered derivatives) 133 . Benzenoid compounds . chemical structure.Aromatic sulphonic acids. ketones and carboxylic acids) will be discussed.Classification of groups and theory of reactivity and orientation. . The study will also include polynuclear and heterocyclic aromatic compounds.). nomenclature and properties.Aromatic nitro compounds. 8. Anthracene and phenanthrene. halo-. 6. nitro-.Introduction. 3. Develop mechanistic understanding of some organic reactions 4. Relate physical and chemical properties to structure. Description: The course focuses on the chemistry of aromatic organic compounds.Aromatic aldehydes and ketones.Aromatic amines and arenediazonium salts.Pyridine.). . . . 2. . Heterocyclic compounds (Six –membered derivatives) .Phenols and aryl ethers. Reactivity and orientation of substituted benzenes (cont. . Polynuclear aromatic compounds . An introduction to the use of spectroscopic methods (UV. 2. IR. Solve organic problems and synthesize selected aromatic compounds from their simple precursors. aldehydes. aromaticity. Reactivity and orientation of substituted benzenes (cont.Halogen derivatives. 7. and Sulphonation 3.Aryl alcohols. Reactivity and orientation of substituted benzenes(cont. aryl alcohols. Selected examples of aromatic organic compounds of medicinal or pharmaceutical use will be discussed. Second Semester Objectives: 1. Classification. Interpret spectral data correctly and apply as a guide to identify structure of Organic compounds. . nomenclature.

and nitro-compounds . 14. Marc London. aldehydes and phenols . furan and thiophene. G. purines.UV and IR Spectroscopy. Vollhardt.Pyrrole. USA. K.. John McMurry Brooks.Organic Chemistry.Azoles. New York. Aromatic hydrocarbons .) . Organic synthesis. 5th Ed.General and special tests 7. 4th Ed.spectroscopic identity (cont. Oxford University Press. (2002).spectroscopic identity (cont. Aromatic carboxylic acids and salts .Ester formation (ethyl acetate. Oxford. Aromatic alcohols. methyl salicylate) References: 1. Neil E.Crystallization.Principles .) . . John Wiley & Sons. 3.Oxidation reaction (toluene oxidation) 10. Spectroscopy (cont.USA. 4th Ed. Examples 9. acid anhydrides and acid chlorides .) .CA. . UK.Laboratory instructions. W. Spectroscopy .Picrate formation (naphthalene picrate) 11. (1995).spectroscopic identity .NMR and MS Spectroscopy.Lassaigne test. Heterocyclic compounds (Five –membered derivatives) . Organic synthesis.spectroscopic identity (cont. Practical: 1. 2.Acetylation of phenols (Aspirin) 12. Aromatic amines .Aromatic halo. Organic synthesis. Peter C. 13.General and special tests 3.Nitration reaction (α-nitronaphthalene) .General and special tests 6.Physical and chemical characteristics 2.General and special tests 8. Purification of organic compounds . 4..Organic Chemistry Structure and Function. Freeman & company. Aromatic esters .Indole.Organic Reactions Simplicity and Logic. Laboratory safety and Scheme of identification .Diazotization reaction (aniline and β-naphthol) . Cole Thomson Learning. Schore. safety measures and glassware.H. Aromatic amides. Pierre Lazlo. ..Sulphonation reaction (p-toluenesulphonic acid) .) . 4. (2002). 12. 134 . Organic synthesis.General and special tests 5.(2000).Organic Chemistry.

Semi-micro-analytical techniques of the qualitative analysis of anions and cations will be discussed. . Pharmaceutical Analytical Chemistry I Course Code: 1805323 Credit Hours: 2+ 1 = 3 Academic Level: Third Year. . Energy and heat of Solutions . Analyze different groups of cations. 6. 3.Types of solutions. 4. concentration and factors affecting solubility. periodic table. orbital and electronic distribution. . . Qualitative analysis . Qualitatively analyze a given unknown inorganic substance. Qualitative analysis .Acid / base strength. First Semester Objectives: 1. precipitation and complexation 8. color reactions. solubility product. Contents: 1. Description: The course focuses on the basics of physical and general chemistry.Halides..The periodic table. Analyze different groups of anions. properties of elements 5.Classification of reactions. Chemical and ionic equilibriums .The sulphur group 9. Anions . 3. . nitrate and nitrite 135 . precipitation and filtration. Perform different chemical equilibriums and have an idea about heat of the matter. Feature the different types of bonding. Chemical kinetics.SI units and Calculations with chemical formulae . common ion effect. 7.Temperature and reaction rate.Bonding. types of chemical bonds and stoichiometry will be also included. The fundamental physicochemical properties of chemical compounds are administered with special emphasis to equilibrium chemistry and thermo-chemistry.Atom structure. The course also deals with the detection and identification of different inorganic substances. 5. electron configuration. Stoichiometry 6.Quantum theory . The study includes flame tests. electrolytes 7. Anions . Apply different units of measurements and calculate concentration of solutions. pH value and water ionization 4. Study of atomic structure.Carbonate and bicarbonate . Calculations with chemical formulae and equation \ Gases . balancing. General chemistry .Internal energy and heat content.Law of mass action. Define the atomic structure and know the electronic configuration of elements.Reactions and equations.Aqueous solutions.Gas laws (ideal) and deviations 2. General chemistry . relation between ΔE and ΔH. 2.

M. Widmer. Anions .Laboratory instructions. Dean's Analytical Chemistry Handbook by Pradyot Patnaik.Qualitative analysis of cations group I 7. Valcarcel.Qualitative analysis of cations group IV 12. M.Qualitative analysis of sulphur group 3. Publisher: McGraw-Hill Professional. Kellner. Cations . Publisher2nd edition 3. Cations . F. M. Mermet. nitrite. Cations . Cations .Qualitative analysis of mixture of anions 6.Qualitative analysis of mixture of anions and cations References: 1.Group III and group IV cations 12. Analytical Chemistry by Gary D. . Mixtures .Group I and group II cations 11. Otto.Qualitative analysis of carbonate and bicarbonate 2. Cations . Skoog. Edited by J. Christian. Donald M. 136 . West. Publisher: Brooks Cole. Fundamentals of Analytical Chemistry (with CD-ROM and InfoTrac) by Douglas A. Introduction . Publisher: Wiley. arsenate and cyanogens group 10. Cations .Qualitative analysis of mixture of cations 13. Revision . H. . 2.Qualitative analysis of halides 4. M. Cations . Analytical Chemistry.Qualitative analysis of cations group II 8.Mixtures of anions and cations Practical: 1.Qualitative analysis of nitrate. Cations . phosphate 5. 6th edition 4. Anions . safety measures and glassware. A Modern Approach to Analytical Science. Anions . Stanley R. Crouch. Founding Editors: R. Cations .Phosphate. James Holler.Mixtures of anions and cations 14. Revision .Qualitative analysis of cations group VI 10.Qualitative analysis of cations group V 11. Cations . Anions .Qualitative analysis of cations group III 9.Qualitative analysis of mixture of anions and cations 14. Mixtures . 8th edition.Group V and group VI cations 13.

weak acids and bases and salts . Quantitatively prepare standard solutions. Complex formation titrations . Non-aqueous titrations . complex formation titrations. reduction oxidation reactions and electrochemical methods of analysis are discussed. Electrochemical analysis . 2. Contents: 1.indicators.Polarography and applications 137 . 2. . Acid-base (neutralization) titrations.Applications of complex formation titrations. Acid-base titrations . Precipitimetry .Introduction .Introduction . spectrofluorometry and chromatography.Buffer solutions and neutralization titration curves 3. Reduction oxidation reactions . 7. Second Semester Objectives: 1. Standard solutions and accurate measuring instruments are presented.pH of strong. .Potentiometry and applications . 4. Reduction oxidation reactions .Applications of Non-aqueous titrations 5.Standard substances. 7. Complex formation titrations .Introduction.Neutralization indicators. Apply different analytical methods to water samples. 6. Analyze samples applying electrochemical or instrumental methods.Methods and applications 8. 6. non-aqueous titrations. Electrochemical analysis . 5. Analyze samples of acids and bases of unknown concentrations.Introduction and redox titration curves 9. precipitimetry.Applications of acid-base titrations 4. grravimetry.Conductometry and applications 11. Pharmaceutical Analytical Chemistry II Course Code: 1805324 Credit Hours: 2+1=3 Academic Level: Third Year. Quantify samples containing halides. Introduction . Acid-base titrations . Applied analysis is administered with special emphasis given to water analysis. . Determine the concentration of a metal ion sample. Calculate concentration of oxidizing or reducing solutions.Introduction . 3. . The course also includes instrumental methods of analysis such as spectrophotometry.Applications of redox titrations 10.Volumetric analysis.Types of quantitative analysis. Description: The course focuses on the principles of quantitative analysis.

Determination of Zinc powder .Spectroscopic methods (spectrophotometry. Instrumental analysis .Colorimetric determination of potassium permanganate .Determination of potassium iodide 10. spectrofluorometry and flame spectroscopy) 13.Determination of mixture of carbonate and bicarbonate 3. HPLC and TLC 14.Standards (preparation and standardization) .Physical characters and chemical examination . West.Determination of pH . 138 .Physical examination of water sample . Analytical Chemistry.Determination of Na. Instrumental analysis .Chemical examination of water sample 14. Instrumental analysis . 2. Reduction oxidation reactions .Detection and determination of impurities Practical: 1.Chemical examination of water sample References: 1. Reduction oxidation reactions .Determination of zinc sulphate . safety measures and glassware. K and Ca ions by flame emission 13. Introduction and Standard solutions . Publisher:Brooks Cole. Fundamentals of Analytical Chemistry (with CD-ROM and InfoTrac) by Douglas A. Water analysis .Determination of glucose 9.Potentiometric determination of Fe(II) by Ce(IV) 11.Determination of amino acids 5.Chromatography (GC. Crouch. Stanley R. A Modern Approach to Analytical Science.Determination of mixture of Ca and Mg 6.Determination of hydrogen peroxide 8. Reduction oxidation reactions . Complex formation titrations . Br and I) 7. Acid-base titrations .Determination of halides (Cl. Electrochemical analysis . 12. . James Holler.Determination of ammonium chloride .Preparation and standardization 2.Physical examination of water sample .Determination of mixture of borax and boric acid 4. Skoog. Donald M. Acid-base titrations .Determination of acetic acid content in vinegar .Colorimetric determination of cerium(IV) sulphate 12. Instrumental analysis . Water analysis . Precipitimetry . Non-aqueous titrations .Laboratory instructions. 8th edition. F. Water analysis .Determination of glycerol .

H. M. 6th edition 4. Kellner. Widmer. M. Publisher: McGraw. Mermet. Otto. Publisher: Wiley.Hill Professional 139 . Valcarcel. Analytical Chemistry by Gary D. Christian. M. M. Dean's Analytical Chemistry Handbook by Pradyot Patnaik. Publisher2nd edition 3. Founding Editors: R. Edited by J.

Medicinal Chemistry I Course Code: 1805425 Credit Hours: 2+ 1 =3 Academic Level: Forth Year.Miscellaneous group.Antimycobacterial drugs 140 . anti-malarials and anthelmintics will be included. Drug design . Antibiotics . Antibiotics . assay procedures and mechanism of action are presented. Know some drug classes including preparation. Study the concepts of drug latentiation and pro-drug formation. Introduction and Factors affecting drug bioactivity . Anti-infective agents .Drug development and lead modifications 2.Physicochemical properties (Solubility. Perform different chemical limit tests according to pharmacopeial requirements. The study of certain pharmaceutical classes used in drug therapy such as anti- infective agents including local anti-infective. 6. partition coefficient and ionization) .Aminoglycsides .Tetracyclines 6. Antibiotics . Description: The principles of medicinal chemistry and its importance in the field of drug design and discovery are presented.β -Lactam antibiotics 5. Contents: 1. identity and assay procedures.Quinolones and fluoroquinolones 8. antibiotics. The course includes a presentation about sources of impurities in pharmaceutical substances and limit tests stated in some pharmacopeias. . identity tests. 6. First Semester Objectives: 1. lincomycins and polypeptides.Chemical structure parametrers . 2. selected methods of preparation. Detect the relationship between physicochemical properties and activity of different drugs.Macrolides. Sulphonamides.Antibacterial sulphonamides . 3.Drug latentation. The chemical structure. Anti-infective agents . anti-amoebic agents. The course focuses on the physicochemical properties in relation to biological action.Structure activity relationship . Understand how drugs function on the molecular level (mechanism of action). 4. Qualitatively analyze some of the studied pharmaceutical substances. pro-drugs and soft drugs 4. urinary tract anti- infective. anti-tubercular.Functional group modifications . antiviral and antifungal agents will be also studied. 7.Identification of the pharmacophore group 3. Drug design . 5.

Williams and 141 .Sodium chloride sample 7.For heavy metals in presence of lead 6.For chloride in sodium sulphate sample . Tests of purity . Anti-infective agents .Glycerol sample .Antiviral drugs and antiAIDS Practical: 1.Introduction. Vol.For sulphate in sodium thiosulphate sample 3. Practical exam References: 1.Qualitative analysis of calcium gluconate injection 11.Qualitative analysis of Tincture iodi 9.Antifungal drugs 13. Anti-infective agents . 3 rd Edition Publisher: Oxford University Press 2. Pharmaceutical analysis . Limit test . Limit test . .VCH 3.For chloride in potassium permanganate sample 2.Qualitative analysis of of zinc content in eye drops 10. Anti-infective agents .Citric acid sample 8. McGuire (Editor) Publisher: WILEY.For sulphate in sodium salicylate sample . Pharmaceutical analysis .For phosphate in sodium chloride sample 4.For heavy metals in absence of lead . 2.Phosphoric acid sample . Anti-infective agents . Limit test . Patrick.For lead in sodium chloride sample 5.For sulphate in sodium chloride sample . 1. Anti-infective agents . 9. Limit test . Anti-infective agents . Pharmaceutical analysis . Limit test . Pharmaceutical analysis .Antiviral drugs 14.For iron in zinc sulphate sample . Pharmaceutical analysis . L. Tests of purity .Qualitative analysis of isonicotinic acid hydrazide 12.Qualitative colorimetric analysis of salicylic acid 13.Antimalarial and antiamoebic drugs 10. Pharmaceuticals. 3 and 4 :J.Antiseptics and disinfectants 12.Anthelmintics 11. Foye's Principles of Medicinal Chemistry by David A.Qualitative colorimetric analysis of tetracycline 14. Pharmaceutical analysis . An Introduction to Medicinal Chemistry by Graham L.

Publisher: Lippincott Williams & Wilkins. John H. Lemke. Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical 6. Williams & Wilkins. Chemistry. 4. 5. 4. Thomas L. 142 . Block and John M. Beale (Editors) Publisher: Lippincott 7.

Alkylating agents.Analyptics and methylxanthines 6.Antidepressants 8. 2. 6. CNS depressants . CNS depressants . 4. Drugs of local anesthetic activity will be also studied. Medicinal Chemistry II Course Code: 1805426 Credit Hours: 1 + 0 =1 Academic Level: Forth. Antineoplastic agents .Skeletal muscle relaxants 14.Antibiotics 4. Mid term exam 9. CNS depressants . CNS depressants . CNS stimulants . Relate between the chemical structure and biological activity of the drugs. CNS stimulants . Know some drug classes including preparation. the mechanism of action and structure activity relationship of such group of the studied drugs will be illustrated.Antidepressants 7. identity and assay procedures. 3.Anxiolytics 12. second semester Objectives: 1.Antipsychotics 15. CNS depressants .General anesthetics 10. Know the chemistry of different groups of the studied drugs. 6. CNS stimulants . In addition.Antiepileptics 13. The chemical structure. Antineoplastic agents .Miscellaneous compounds 5. selected methods of preparation. Understand how drugs function on the molecular level. Demonstrate how to avoid undesirable side effects of the studied drugs. suggest methods of analysis for some of the studied pharmaceutical substances Description: The course focuses on pharmaceutical classes used in the treatment of cancer. identity tests and assay procedures are also introduced. CNS depressants . The course also discusses different drugs affecting the central nervous system including these of stimulating and those of depressant actions. Antineoplastic agents . 3. 5.Sedatives and hypnotics 11. Antineoplastic agents . 2. Local anesthetics 143 .Anti metabolites. Contents: 1.

. Foye's Principles of Medicinal Chemistry by David A. 1.VCH 2. Publisher: Lippincott Williams & Wilkins. 3 and 4 :J. McGuire (Editor) Publisher: WILEY. Vol. Beale (Editors) Publisher: Lippincott Williams & Wilkins. Products and structure activity relationship References: 1. Williams and Thomas L. 144 .Lemke. Block and John M.Mechanism of action. 3. L. 2. Pharmaceuticals. Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry. John H.

Diuretics . 7. Demonstrate how to avoid undesirable side effects of the studied drugs.High ceiling (Loop) diuretics . Analgesics either these having narcotic action and those of non narcotic activity as well as non steroidal anti- inflammatory agents and drugs used for the treatment of gout will be studied.Cardiotonic agents . Contents: 1. identity and assay procedures. selected methods of preparation. Cholinergic drugs 145 . Adrenergic drugs .Aliphatic amines and respiratory drugs 8. Qualitatively analyze some of the studied pharmaceutical substances.Antihyperlipidemic agents 5.Potassium sparing diuretics 6. Description: The course focuses on pharmaceutical classes used in the treatment of cardiovascular disorders. 2. the drugs acting as H1 and H2 antagonists are presented.Anticoagulants. antithrombotic & thrombolytic 4.Sympathomimetics 7. Cardiovascular drugs . Medicinal Chemistry III Course Code: 1805527 Credit Hours: 2 + 1 =3 Academic Level: Fifth. 3. the mechanism of action and structure activity relationship of such group of the studied drugs will be illustrated.Antihypertensive drugs 2. Cardiovascular drugs . Adrenergic drugs . Know the chemistry of different groups of the studied drugs.Hemostatics and antifibrinolytics . 6.Osmotic and thiazide diuretics . Predict the biological response. The chemical structure. Cardiovascular drugs .. Mid term exam 9. Moreover. 4.Antianginal and antiarrythmic drugs . The course also discusses different drugs affecting adrenergic and cholinergic receptors and those used as diuretics. 5. Cardiovascular drugs . Relate between the chemical structure and biological activity of the drugs. if any from the chemical structure.Antihypertensive drugs 3. Perform different chemical limit tests according to pharmacopeial requirements . In addition. identity tests and assay procedures are also introduced. first semester Objectives: 1. Know some drug classes including preparation.

2nd Generation antihistaminics 15. Pharmaceutical analysis . Pharmaceutical analysis .Dipyrone .Sedative mixture 8. Cholinergic drugs .Assay of ibuprofen and indomethacin 3.Thiamine hydrochloride (vitamin B1) 10.Identity.1st Generation antihistaminics .Synthesis and assay 4. Pharmaceutical analysis . Analgesics .Compound sodium lactate intravenous injection 12.Drug report 14. Pharmaceutical analysis .Aspirin Monograph .Oral Rehydran salts 11. 3 146 .Drug report 15. Pharmaceutical analysis .Arylacetic acid derivatives . Pharmaceutical analysis . Non Steroidal antiinfammatory agents .Ascorbic acid (vitamin C) .Selective COX inhibitors . Pharmaceutical analysis . H2-receptor antagonists .Cholinergic agonists 10. Pharmaceutical analysis . Patrick. Pharmaceutical analysis . Pharmaceutical analysis .Arylacetic acid derivatives 13. Pharmaceutical analysis .Opoid analgesics 12. Non Steroidal antiinfammatory agents .Cholinergic blocking agents 11. Practical exam 9.Paracetamol .Salicylates.Methyldopa . H1-receptor antagonists . purity tests. phenamates .Antiulcer drugs and proton pump inhibitors Practical: 1.Hamodialysis solution 13. . Practical exam References: 1.Anticoagulant acid citrate-glucose solutions 7.Chloral hydrate 6. Pharmaceutical analysis .Frusemide 5. An Introduction to Medicinal Chemistry by Graham L.Uricosuric agents 14.Nifedipine . synthesis and assay 2. Pharmaceutical analysis .

John H. Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry. Publisher: Lippincott Williams & Wilkins. Foye's Principles of Medicinal Chemistry by David A. Vol. Pharmaceuticals. 2.Lemke. L. 147 . Block and John M. Beale (Editors) Publisher: Lippincott Williams & Wilkins. 3 and 4 :J. 1. rd Edition Publisher: Oxford University Press 2. 4. McGuire (Editor) Publisher: WILEY-VCH 3. Williams and Thomas L.

2. pathways and its importance in drug design and discovery are presented. identity tests and assay procedures are also introduced. Vitamins 148 . identity and assay procedures. The course focuses on pharmaceutical classes used in the treatment of metabolic disorders and endocrine functions including peptide and steroid hormones. Know some drug classes including preparation.Estrogens 5. Insulin and anti-diabetic drugs . Second Semester Objectives: 1. Contents: 1. Drugs for metabolic diseases and endocrine functions . selected methods of preparation.Peptidomimetics -Thyroid hormones and antithyroid drugs 4. Know how to perform medicinal chemistry case study 8.Fat and water soluble vitamins 9.Adrenocorticoids 7. In addition. Know different types of quality control and applications. 5. the mechanism of action and structure activity relationship of such group of the studied drugs will be illustrated.Oral anti-diabetics 8. Drug metabolism .Peptide hormones .Factors influencing metabolism .Androgens and anabolics . Understand the relevance between medicinal chemistry and clinical applications. 6. Steroid hormones: Female sex hormones . 3. Different types of quality control will be studied.Pathways of drug metabolism (phase I & II). Drug metabolism . 4. Medicinal Chemistry and Quality Control Course Code: 1805528 Credit Hours: 2+0=2 Academic Level: Fifth Year. Male sex hormones and Adrenocorticoids . The chemical structure. Steroid hormones: Female sex hormones .Estrogens . Different types of vitamins and anti ageing drugs will be presented.Progestin 6. Description: The principles of drug metabolism.Insulin prepartions .Drug design depending on metabolism. if any from the chemical structure. Demonstrate how to avoid undesirable side effects of the studied drugs. Vitamins . Know the chemistry of different groups of the studied drugs. The course also discusses the relevance between medicinal chemistry and clinical applications. 2. 7. 3. Predict the biological response. Relate between the chemical structure and biological activity of the drugs.

Quality control . L.Medicinal chemistry case study 11. 1. . Pharmaceuticals. Beale (Editors) Publisher: Lippincott Williams & Wilkins.Anti-aging drugs 10. 2. Foye's Principles of Medicinal Chemistry by David A. Clinically relevant medicinal chemistry . Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry. 3 and 4 :J. 3. Quality control . Publisher: Lippincott Williams & Wilkins. John H. Quality control .Good analytical and laboratory practice 14.Biopharmaceutical and other types of quality control References: 1.Medicinal chemistry case study 12.Water soluble vitamins .Lemke. Vol. Williams and Thomas L. Block and John M. 149 . McGuire (Editor) Publisher: WILEY-VCH 2. Clinically relevant medicinal chemistry .Physical and chemical quality control 13.

Umm Al-Qura University Faculty of Pharmacy Elective Modules 2008 150 .

massage therapy.Application • Nutraceuticals . pharmaceutical science. This course will provide a broader perspective to undergraduates in certain fields including medicinal chemistry. heart disease.Defination .Types of essential oils . • Learn the principle of identifying medicinal plants and understand their medicinal uses • Understand the fundamentals of phytotherapy • Understand the relevance between medicines and poisons. acupuncture.etc • Understand the importance of medicinal plants to medicine development • Understand fundamental concepts of medicinal plants and different methods of classification. The history and classification of medicinal plants are also discussed. pharmacology. pharmacognosy.History . Contents: Alternative medicine Introduction to alternative medicine • Different types of alternative medicine • Aromatherapy . using an evidence based approach. ethnobotany or herbal practice.Application • Ayurveda . Alternative and Herbal Medicine Course Code: 1802566 Credit Hours: 2 Academic Level: Fifth Year Objectives: At the end of this course the student should be able to: • Understand the concept of alternative medicine • Acquire a good knowledge about the different types of alternative medicine as nutraceuticals.Basic principals • Apitherapy -Different honeybee products .Definition . Special attention will be focused on plants that have been used for the treatment of human diseases such ac cancer. nervous system disorders. aromatherapy…. cheirology. acupuncture. and other disorders. herbal remedies. The course will cover the different methods for quality control of medicinal plants to ensure that the highest degree of safety and effectiveness is achieved. A review of toxic plants is also included. massage therapy.Examples -Application 151 .Overview of the concept . Description: Alternative and Herbal Medicine Topics introduce the student to a variety of complementary and alternative medicine topics including nutraceuticals and herbal remedies.

Joanne Barnes.Categories of Chinese prescription Herbal Medicine • Introduction of Medicinal Plants • History of Medicinal Plants and Ethnobotany • Fundamentals of Phytotherapy • Classification of herbs according to their properties. and Elizabeth M. Simon Gibbons. Evidence-Based Medicine and Complementary and Alternative Therapies. Williamson • Curtis P.Categories of Chinese herbs . • The Convergence of Complementary. uses and active constituents • Methods for quality control of medicinal plants • Toxic Plants References: • Fundamentals of Phyarmacognosy and Phytotherapy by Michael Heinrich. • Traditional Chinese medicine -Historical background and classical sources . Alternative & Conventional Health Care: Education Resources for Health 152 .

although they are often necessary for treatment. Otitis media 4. The use of many medications that do not receive approval from the Food and Drug Administration for use in the pediatric age group. Description: The aspect of drug use in paediatrics will be given special emphasis that include the following: medication dosing for infants and children is based on their weight or body surface area. Human immunodeficiency virus 9. the effect of drugs use on the central nervous system. polypharmacy and drug use. Contents: 1. Fever 16. Cough/Cold 17. cardiovascular. pharmacology. and the ability to utilize different drug formulations. Respiratory Distress Syndrome 14. Course content will augment the College of Pharmacy curriculum with regard to pathophysiology. Pharmacokinetics 2. and active learning techniques will be utilized to enhance the learning experience. and the psychosocial aspects of responsibility for one’s health and compliance. pharmacokinetic and pharmacodynamic changes. gastrointestinal. Fluid and electrolytes 7. a broad variety of topics. growth and development influence medication usage through alterations in a given medication’s pharmacokinetics. The student will develop an understanding and appreciation of the issues of paediatrics. Medication Errors 19. risk evaluation in the use of specific drugs. Growth and development 153 . and requires individualized calculations. The course discuss also compounding of medications as a potential source of error. and therapeutics. Bronchiolitis 15. Pediatric Asthma 20. Cystic fibrosis 10. Meningitis 3. Finally. muscular and bone. which will translate into an increased sense of respect and knowledge when caring for the children in practice. sinusitis 5. pharyngitis 6. and urinary systems. Congenital heart disease 8. Paediatric Pharmacy Course Code: 1804563 Credit Hours: 2 Academic Level: Fifth Year Objectives: This course is to provide the student with a strong foundation in the care of the paediatrics. Childhood immunization 12. Immunizations 18. Lectures. Pediatric epilepsy 11. Prematurity 13. and its effect on the use of drug.

Dysplasia 154 . Attention Deficit Disorder 26. Dosing calculation 22.21. Herbal therapies 25. Acetaminophen Toxicity 24. Counseling 23.

Contents: 1.cognitive impairment .) . dysarthria .pressure sores (decubiti) . risk evaluation in the use of specific drugs.infectious diseases (UTI.pain control 2.diabetes mellitus .) . This course is to provide the student with a strong foundation in the care of the older adult.cerebrovascular disease (strokes.arthritis .visual and hearing impairment .depression/anxiety . polypharmacy and drug use. which will translate into an increased sense of respect and knowledge when caring for the elderly in practice.) .chronic renal failure . peripheral vascular disease. pharmacokinetic and pharmacodynamic changes.visual and hearing impairment . and physiology 2. and active learning techniques will be utilized to enhance the learning experience. 4. anticancer agents and health in men and women. aphasia. skin & soft tissue) . Description: The aspect of drug use in geriatric will be given special emphasis that include the following: aging processes and its effect on the use of drug. Age related alterations in pharmacodynamics. the effect of drugs use on the central nervous system. arrhythmias.independent activities of daily living (IADLs) . TIAs. 3. pharmacokinetics 1. etc. Geriatric Pharmacy Elective Course Code: 1804564 Credit Hours: 2 Academic Level: Fifth Year Objectives: 1. Lectures. a broad variety of topics.cardiovascular disorders (hypertension. Major Disease States Reviewed: .congestive heart failure.constipation/diarrhea . etc.activities of daily living (ADLs) . gastrointestinal. pharmacology. Patient Assessment . The student will develop an understanding and appreciation of the issues of aging. Communication and special counseling needs of geriatric patients .dysphasia.chronic obstructive pulmonary disease . .cognitive impairment 155 . and urinary systems.peptic ulcer disease . and therapeutics.Parkinson’s disease . etc. 2.organic brain syndrome (dementias. Course content will augment the College of Pharmacy curriculum with regard to pathophysiology. pneumonia. muscular and bone.drug therapy evaluation 3. cardiovascular.urinary incontinence . The evaluation of drug in geriatric will include the use of antibiotics.

regulations .advanced directives .4. Legal/ethical issues involved in the care of the elderly .end of life decisions 156 .

and drug therapy problems (e. .. illness. overview of disease.An understanding of the role of the community pharmacist as a primary care provider who identifies and solves drug related problems 1. Detect. Developing therapeutic goals 4. . and various treatment methods. 3. Community Pharmacy Elective Course Code: 1804565 Credit Hours: 2 Academic Level: Fifth Year Objectives: .An understanding of the interaction of the pharmacist with health care providers regarding drug selection. allergies. Demonstrate the use of selected home health care products. etc. Obtain an accurate medical history of past and present prescription and OTC drug therapy. drug information. Communicate with health care providers verbally and in writing when necessary by appropriately seeking information. Counsel and teach patients regarding the appropriate use of prescription medication. and personal life situations. and medical supplies using both oral and written information. 4.g. Answer with proper documentation drug related questions from the public. Perform triage functions in discussing health related problems with patients and referring them to appropriate health care providers or recommending appropriate self-care. critically evaluating each component . 1. current history.An understanding of the stepwise process used to identify and solve those problems 1. Identifying these problems 3. Be able to perform blood pressure and blood glucose determinations and other self-monitoring and diagnostic procedures. Construct an organized comprehensive case presentation including the patient's past history. and drug therapy monitoring. 2. Formulating realistic solutions to the problems 5. Monitoring the implementation of the solution to achieve the set goals 8. report and follow up adverse drug reactions. noncompliance and other potential drug therapy problems . Choosing the most appropriate solution 6.An understanding of the Health Care needs of a community and the individuals within that community 1. drug interactions. Collection of the information necessary to discern if the patient has a drug related problem 2. 3. Implementing the solution 7. providing 157 . Evaluate a patient's drug regimen in the context of medical problems. medication compliance. OTC medications.Recognition of the most common drug related problems 1.) 2.

1. assessment of medical and medication histories. 2. drug information and influencing prescribing behavior in the interest of the patient.An understanding of the topics discussed and situations encountered during the clerkship demonstrated by completing a test at the end of the month covering those items. . Otic Preparations 16. Participate in the community pharmacy management activities as related to the delivery of patient care services. Maintain a notebook compiling the answers to drug related questions answered during the course of the month .An understanding of the basic logistics behind operating a clinically active community pharmacy 1. Bacterial/Fungal skin infections 10. Cold and Allergy 4. This course aims to provide knowledge and skills related to the use of nonprescription drugs and minor illnesses. and plan for follow-up Contents: The student be prepared to discuss one topic from the list provided below. . identifying and list of patient’s problems. These should prepared by the students as an informal presentation of the topic. Laxatives 6. Acne Medications 11. Dermatitis/Uticaria/Insect Bites 12. psychological. monitoring therapy. Stomach Upset/Diarrhea 9. The student should be prepared to answer questions asked by the preceptor. Poison Prevention 15. Diagnostic Testing Products 8. design strategy and treatment plan. OTC Diet/Weight control 2. Nutrition/Vitamins 3. The emphasis are in the area related to the analysis of signs and symptoms of minor illnesses. Infant Nutrition 158 .Recognition of the impact of social. Description: This course provides an understanding of the theory and concept of pharmaceutical care in the contexts of primary care to the community. OTC Diabetes Products 14. and economical factors on drug therapy selection and use. Drugs in Pregnancy 7. OTC Contraception 13. Ophthalmic and Contact lens preparations 5. OTC Cough.

17. OTC Analgesics 19. OTC Sports Injury Treatment 18. Folk Medicine Home Remedies 159 .

Cytotoic Drugs and The Cell Cycle 4. 2.Individual alkylating agents 6. loss of function. the student will be able to: 1. 6.Cytotoxic antibiotics (antitumor antibiotics) 12. Contents: 1. State the advantages of drug combination in cancer chemotherapy. the genesis of a cancer cell.Drugs used in cancer chemotherapy 3. the cell cycle.g.Purine antagonists (purine analogues) 9.Pyrimidine antagonists (pyrimidine analogues) 10. uncontrolled proliferation. 7. List the hormones used in cancer chemotherapy. -Two chosen drugs as prototypes with reference to their therapeutic uses and adverse effects. -Main adverse effects.Antimetabolites (structural analogues) 7. 2.Classification of Anticancer Drugs. iii. State for each hormone (or anti-hormone) mechanism of action. invasiveness. Chemotherapy Course Code: 1804567 Credit Hours: 2 Academic Level: Fifth Year Objectives: By the end of this topic.Alkylating agents and related compounds 5. Vinca Alkaloids 11. 4. ii.Introduction: Cancer therapeutic modalities.Hormonal agents 13. metastasis. Relate the action of cytotoxic drugs to the cell cycle. indications and adverse effects. -Common mechanism (s) of action. Classify anticancer drugs into various groups. 5. State for each group: i.Miscellaneous anticancer drugs 160 .Folic acid antagonists 8. 3.Plant alkaloids e. the biology of cancer. List the main lines in management of cancer.

14- Drug combinations
References: Basic & Clinical Pharmacology (ninth edition) Bertram G.
Katzung.

161

Pharmaceutical Management and Marketing
Course Code: 1803564
Credit Hours: 2
Academic Level: Fifth Year
Objectives: 1. Understand the concepts of pharmaceutical management and
marketing.
2. Discuss major items for a successful marketing plan.
3. Appreciate the importance of the management criteria;
salesmen, advertisement, etc.
4. Develop a plan for marketing an idea, organization, or
product.
5. To understand the problems and issues faced by
pharmaceutical marketers. pharmaceutical industry.
6. To critically appraise pharmaceutical marketing studies.
7. To gain a thorough understanding of the pharmaceutical
marketing literature and some research methods employed.
8. To discuss the role of marketing in the success and failure of
the pharmaceutical industry.
9. To identify potential research ideas in marketing.
10. Understand the environment of marketing in pharmacy.

Contents: 1. Management
Nature and principles of management, types and functions of
managers.

2. Plant location and lay out of an industry Various factors
affecting locational aspects, lay out of building and equipment,
product layout Vs. process layout, compliance of pollution
control measures. Elementary knowledge of Factories Act.

3. Planning and Decision making: Definition, importance of
planning, steps involved in decision making, objectives,
strategies, policies and programme.

4. Planning (continue); Forms of operations control.
Requirements for adequate control. Critical control points and
standards. Motivation, innovation and creativity, communication.

5. Management by objective – MBO process, objectives,
multiplicity.

6. Planning; Purpose and types of planning, steps in planning.
Organizing, management control systems. Purpose, steps in the
control process.

7. Production planning and Control Scientific purchasing, quality
control, problems of productivity, stores organization, location of
store, receiving, inspection and issue of materials; control of
stores and stocks, stores accounting and records.

162

8. Personnel Management Selection, appointment, training,
transfer, promotion and demotion, remuneration, job evaluation,
human relations.

9. Pharmaceutical Marketing Functions, buying, selling,
transportation, storage, finance, feedback information, channels
of distribution, wholesale, retail, departmental store, multiple
shop and mail order business.

10. Marketing Management
Marketing channels, promotion, advertising and salesmanship.
Promotion marketing.

11. Sales Management
Personnel, buying, receiving and pricing, Sales promotion and
customer services. Sales forecasting: Various methods, analysis,
limitations and advantages

12. Salesmanship; Principles of sales promotion, advertising,
Ethics of sales, merchandising, literature, detailing.

13. Finance; Principles of economics with special reference to
the laws of demand and supply, demand schedule, demand
curves, labour welfare, general principles of insurance and inland
and foreign trade, procedure of exporting and importing goods.

14. Pharmacy Layout Design
Objectives of layout design. Types of community pharmacies.
Pharmaceutical centre, prescription-oriented pharmacies,
traditional pharmacies, the super drug store.
Consumer goods and purchases. Classes of layout designs.
Principles and characteristics of layout design. Traffic flow
analysis

163

Theory of distillation of mixtures (a) binary mixtures of miscible liquids. chain conveyer. refrigeration. raw materials.Primary function of the pharmaceutical pilot plant. humidification and dehumidification equipment. Contents: 1. screw conveyer. 7. compressors. appreciate the concept of fluid flow. 6. 4. mechanism of fluid flow. Humidity and humidity chart. Distillation. 4. 5. 10. Bernoulli's theorem. pneumatic conveyers. pipe fittings. belt conveyers. 2. . material and energy balances. (c) Rectification rectifying columns fractionating column and simple calculations. personnel requirements. . Understand the conversion of a drug product from the developmental stage to the batch production. Industrial equipment for vacuum. ejectors.Factors to be considered during development. Define the conveying process in the manufacture. . Pilot Plant Scale-Up Techniques. reflux and molecular distillation. Understand the concepts of pharmaceutical operations. . 6. steam. 164 . measurement of flow of fluids. Explain the importance of water conditioning and waste water treatment. Introduction. friction losses.Humidity and air conditioning. Conveyance of manufactured materials.Relevant processing equipments. . Theory of SCF. Undersatnd the theory of distillation. transportation of gases. 2. 5. blowers. wet bulb temperature. Pilot Plant Scale-Up Techniques.Review of the formula. Advanced Industrial Pharmacy Course Code: 1803565 Credit Hours: 2 Academic Level: Fifth Year Objectives: 1.Production rates. . 3.Pilot plant design for tablet development. Understand the theory of supercritical fluid technology and its application. 9. . Transportation of fluids Pipe joints. McCabe Thiele method for calculation of theoretical plates. 3.Reporting responsibilities. Flow of fluids Manometers. Conveying: Types of conveyers. particular drug delivery techniques using SCF. 7.Process evaluation and master manufacturing procedures. Supercritical Fluid (SCF) Technology. enlargement and contraction losses. (b) binary mixtures of immiscible liquids. wet bulb theory. 8. space requirements. pumps. . Elements of industrial stoichiometry. Plate efficiency.

gas antisolvent recrystallization (GAS). precipitation with compressed antisolvent (PCA) and aerosolized supercritical extraction of solvents (ASES). supercritical antisolvent recrystallization (SAS). 13. 12. Industrial gases. 11. Supercritical fluid Technology (conitinue). supercritical fluid nucleation (SFN). 165 . water conditioning and environmental protection. Solution enhanced dispersioin by supercritical fluids (SEDS). rapid expansion of supercritical solution (RESS).

Fat-Soluble Vitamins 4. Define "vitamin" and "trace elements" Know whether each vitamin is classified as fat-soluble or water-soluble 2. Contents: 1. Sources. Trace Elements 3. 6. Describe disease states or drugs that may cause vitamin or mineral deficiency 5. Vitamin Therapy 7. Disease Treatment. References: An Evidence-Based Approach to Vitamins and Minerals: Health Implications and Intake Recommendations by Jane Higdon. Recognize the U. Function. Describe the signs and symptoms of individual vitamin and mineral deficiencies. 2003 166 . Know the major functions of individual vitamins and minerals in humans 4. Disease Prevention. Deficiency. Minerals 2. Sources. Safety and Recommendation for intake for each vitamin and essential mineral.S. Safety and Recommendation for intake for each of the following: Biotin / Folic Acid / Niacin / Pantothenic Acid / Riboflavin Thiamin / Vitamin A / Vitamin B6 / Vitamin B12 / Vitamin C Vitamin D / Vitamin E / Vitamin K / Calcium / Chromium Copper / Fluoride (Fluorine) / Iodine / Iron / Magnesium Manganese / Molybdenum / Phosphorus / Potassium Selenium / Sodium Chloride / Zinc. Water-Soluble Vitamins 5. Disease Prevention. Know the clinical effects of excessive administration of vitamins Know the major nutraceuticals available OTC Description: Function. diseases due to vitamin deficiency 6. Vitamins and Minerals Course Code: 1804587 Credit Hours: 2 Academic Level: Fifth Year Objectives: 1. Deficiency. RDA values for individual major vitamins and minerals Know dietary sources of the various vitamins and trace elements 3. Disease Treatment.

rheology of nail products. nail and eye. . Packaging: Package development and design for cosmetics including aerosol pack. 2. Irritation. Stability-testing and performance evaluations of modern-day cosmetic.Understand the concept of cosmetic and dermatologic preparation. Manufacturing techniques (cont. cosmetic surgery and contact lenses. Rheology of cosmetics: Rheological activities of cosmetics. powders. sunscreens and pharmaceutical dermatologicals. deodorants. Manufacturing techniques: cosmetic creams. 8. microbiological and psychometric evaluation of cosmetics. Preservatives: Design and assessment of preservative system for cosmetics. 12.): lotions.Prepare different types of cosmetic preparations. Regulatory requirements: Manufacture and scale up of cosmetics. . physicochemical. sensitization. Contents: 1. toiletry and pharmaceutical topical products. antiperspirants and deodorants 13. photo-allergy. gels. . makeups. hair products. 10. 9. 11.). 167 . Manufacturing techniques (cont. Physiological considerations: skin. antiperspirants. Cosmetic Preparation Course Code: 1803568 Credit Hours: 2 Academic Level: Fifth Year Objectives: . 14. Clinical safety testing. tooth past. 6. dentifrices. hair. multiple and microemulsion. validation of preservative in cosmetic products and factors affecting activity of preservatives. 4.Understand the new trends in cosmetic/dermatologic industry. permanent hair coloration. shampoos. creams and lotions. sticks 3.Appreciate the safety concept of cosmetic preparation. Advances in cosmetics (continue): Hair planting. Evaluation of cosmetics: Performance. 5. herbal cosmetics: formulation and development. 7. compacts. photo-irritation. ocular irritation and protocols for the same. Advances in cosmetics: Liposomes.

8 Pharmaceutics Basic Siences Pharmacy Sciences 99 55.C 2 2 0 Medical Phsics 3 2 1 Biochemistry 3 2 1 Pharmacogonosy 2 3 2 1 Pharmacogonosy 4 4 3 1 Therapeutics 2 3 2 1 Medical Ethics 2 2 0 Pharm. Chem. Ph. Profession 1 1 0 Basic Pharmacokin 2 2 0 Pharmacogonosy 3 3 2 1 Elective I 2 2 0 Pharm.9 178 130 48 Pharmacology Quran & Prophet English Language 12 6. Organ Chem 2 3 2 1 Biopharmaceutics 2 2 0 Medicinial Chem. Chem. Pharm First Year Second Year Third Year Fourth Year Fifth Year Syllabus CU T P Syllabus CU T P Syllabus CU T P Syllabus CU T P Syllabus CU T P Holy Quran 101 2 2 0 Holy Quran 201 2 2 0 Holy Quran 301 2 2 0 Holy Quran 401 2 2 0 Industrial Pharmacy 3 3 0 Arabic Language 101 2 2 0 Islamic Culture 201 2 2 0 Pharmacogonosy 1 3 2 1 Medicinial Chem.2 3 2 1 Elective III 2 2 0 Research Project 3 0 3 19 15 4 18 13 5 19 13 6 16 13 3 17 10 7 Total C. 2 2 0 Analy.6 Clinical Pharmacy Arabic Language 178 Pharmaceutical Chemistry Elective & Research 168 . 2 1 1 0 First Aid 1 0 1 Learning Skills 2 2 0 Pharmaceutics 2 4 3 1 Pharmacology 2 3 2 1 Clinical Pharmacology 2 2 0 Elective II.‫ﺟﺎﻣﻌﺔ أم اﻟﻘﺮى‬ Umm Al-Qura University ‫ﻛﻠﯿﺔ اﻟﺼﯿﻠﺔ‬ Faculty of Pharmacy ‫اﻟﺨﻄﺔ اﻟﺪراﺳﯿﺔ ﻟﻨﯿﻞ درﺟﺔ اﻟﺒﻜﺎﻟﻮرﯾﻮس ﻓﻲ اﻟﺼﯿﺪﻟﺔ‬ ( Programme for Bachelor of Pharmacy ( B.1 3 2 1 Pharmaceutics 3 3 2 1 Pharmaceutics 4 3 2 1 Pharmaceutics 1 3 2 1 Pharmacy Law & Ethics 1 1 0 16 12 4 19 15 4 20 15 5 17 13 4 17 11 6 Syllabus CU T P Syllabus CU T P Syllabus CU T P Syllabus CU T P Syllabus CU T P Islamic Culture 101 2 2 0 Prophet Profile 2 2 0 Islamic Culture 301 3 3 0 Islamic Culture 401 2 2 0 Hospital Pharmacy 2 0 2 English Language 6 4 2 Microbiology 3 2 1 Molecular Biology 3 1 2 Biostatistics 3 2 1 Pharm. Organ Chem.1 3 2 1 Principles of Drug Information 1 1 0 Medicinial Chem 3 3 2 1 Approach to Medical Sci 4 3 1 Physiolog y 3 2 1 Pharmacology 1 4 3 1 Pharmacology 3 3 3 0 Toxicology 3 2 1 Summer Training 320 CU Summer Training 320 CU Computer science 2 1 1 Anatomy & Histology 3 2 1 Pathology 3 2 1 Clinical Pharmacokinetic 1 0 1 Research Project 3 0 3 Approach to Pharm. Chem 4 & Q. ‫ ﻣﻜﺔ اﻟﻤﻜﺮﻣﺔ‬.1 3 2 1 Therapeutics 1 3 2 1 First Semester English Language 6 4 2 Mathematics 2 2 0 Analy.7 Pharmagonosy English Language Basic Sciences 46 25. Administration 2 2 0 Second Semester Approach to Med Scineces 4 3 1 Physiology 3 2 1 Immunology 2 1 1 Dispensing Med 4 3 1 Med. Ph.U 35 27 8 37 28 9 39 28 11 33 26 7 34 21 13 CU % CU T P University requirements21 11.