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*Based on data provided by ASEBIO associated companies. APRIL 2013.
Spanish White Biotech Pipeline
*
www. as e bi o. c om
BIOPRODUCTS
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Company Name Indication Basic R&D Applied R&D
Ready for
exploitation
Industrial
scale up
Available
Technology
transfer in process
Patent
ABENGOA BIOENERGA DDGS (Dried Distillers Grains with Solubles) <<<<<<<<<<<<<<< 4
ABENGOA BIOENERGA Sugars <<<<<<<<<<<<<<< 4
ALGAENERGY Microalgae products with excellent properties for several applications and sectors <<<<<<<<<<<<<<< 4 4 4
Bioibrica Terra-Sorb Biostimulant <<<<<<<<<<<<<<< 4
Bioibrica Inicium Biostimulant <<<<<<<<<<<<<<< 4
Bioibrica StressSal Biostimulant <<<<<<<<<<<<<<< 4
Bioibrica Terramin Biostimulant <<<<<<<<<<<<<<< 4
Bioibrica Terra Humic Biostimulant <<<<<<<<<<<<<<< 4
Bioibrica AminoQuelant Bioavailable Nutrition <<<<<<<<<<<<<<< 4
Bioibrica Optimus Plant protection <<<<<<<<<<<<<<< 4
Bioibrica Armurox Plant protection <<<<<<<<<<<<<<< 4
Bioibrica Cera Trap Biological Attractants <<<<<<<<<<<<<<< 4
Bioibrica Dacus Trap Biological Attractants <<<<<<<<<<<<<<< 4
Bioibrica Mosca Trap Biological Attractants <<<<<<<<<<<<<<< 4
Bioibrica Suzukii Trap Biological Attractants <<<<<<<<<<<<<<< 4
Bioibrica Flyral Biological Attractants <<<<<<<<<<<<<<< 4
Bioibrica Biocebo Biological Attractants <<<<<<<<<<<<<<< 4
GAIKER - IK4 Antibacterial polymers and coatings and evaluation of biocide properties <<<<<<<<<<<<<<< 4
GH Genhelix GHL-11001 / 11002 GHL-11001 11002 and MaB Biosimilar <<<<<<<<<<<<<<< 4 4
INKEMIA IUCT GROUP GC-S51 New solvent from renewable materials for synthesis of APIs <<<<<<<<<<<<<<< 4 4
INKEMIA IUCT GROUP CAT-Apudp / Bcpym / Hmudp New catalyst pyrimidin phosphorilase nucleoside <<<<<<<<<<<<<<< 4 4
INKEMIA IUCT GROUP CAT-Bcun - Gbspum - Ssdeod New catalyst Purin Phosphorilase Nucleoside <<<<<<<<<<<<<<< 4 4
INKEMIA IUCT GROUP GC-BIO-DF / GC-BIO-F 2-deoxy-5-uorouridine. 5-uorouridine. Anticancer / Colon & Pancreas / Colon & Brust <<<<<<<<<<<<<<< 4 4 4
INKEMIA IUCT GROUP BIO-TFT Triuorothymidine / Antiviral (Oftalmic) / Herpes Cornea <<<<<<<<<<<<<<< 4 4 4
INKEMIA IUCT GROUP GC-BIO-DAP / BIO-AP 2,6-diaminopurine deoxiriboside. Anticancer / 2,6-diaminopurine riboside. Antiviral. Anticancer <<<<<<<<<<<<<<< 4 4 4
INKEMIA IUCT GROUP GC-S79 Solvents from renewable materials for the biodiesel sector <<<<<<<<<<<<<<< 4 4
INKEMIA IUCT GROUP SOL-LAOC4 / GC-S77 / GC-DMA New solvent from renewable materials for metal degreasing and for Paint and barnishes/ from DMA <<<<<<<<<<<<<<< 4 4 4
PROTEOS BIOTECH PROTEOS-RPROT Recombinant proteins and growth factors <<<<<<<<<<<<<<< 4
PROTEOS BIOTECH PROTEOS-PCAI Personal care active ingredients and products <<<<<<<<<<<<<<< 4
INKEMIA IUCT GROUP GC-S78 New solvent from renewable materials for Crop protection <<<<<<<<<<<<<< 4 4
X-Pol Biotech X-Pol Biotech Phi 29 DNA polymerase (wild type) <<<<<<<<<<<<<< 4 4
X-Pol Biotech X-Pol Biotech QualiPhi (next-gen version of Phi 29 DNA polymerase) <<<<<<<<<<<<<< 4 4
ABENGOA BIOENERGA Cellulolytic and hemicellulolytic enzymes <<<<<<<<<<<<<< 4
ABENGOA BIOENERGA Microalgae collection <<<<<<<<<<<<<
X-Pol Biotech X-Pol Biotech New Primase / Polymerase <<<<<<<<<<<< 4
X-Pol Biotech X-Pol Biotech New polymerases for Next Generation Sequencing <<<<<<<<<<<< 4
Biomar IB-Cosmtica Extract antifungal <<<<<<<<<<< 4
INKEMIA IUCT GROUP Bio-EPS New exoplysacharides use as nutraceutical and cosmetics (8 compounds) <<<<<<<<<<< 4
INKEMIA IUCT GROUP CAT-Halo1 / Halo2 Enzymatic mixture with hidrolytic activity / with lipase and protease activity <<<<<<<<<<< 4
INKEMIA IUCT GROUP CAT-Halolip / Haloprot New halolipase / New haloprotease <<<<<<<<<<< 4
X-Pol Biotech X-Pol Biotech New polymerases <<<<<<<<<<< 4
INKEMIA IUCT GROUP BIO-K3 Menadione (vitamin K3) <<<<<<<<<< 4 4
ABENGOA BIOENERGA n-butanol <<<<<< 4
REPSOL New microalgae strain with high oil production <<<<<< 4
REPSOL Microorganisms for biofuel production <<<<
INKEMIA IUCT GROUP BIO-CEM New microorganisms for self healing concrete <<< 4
CIBER-BBN BBN-F1 aF4. Rare Diseases << 4
CIBER-BBN Biomaterial with metallic coating. Polymeric material. Bone regeneration << 4
CIBER-BBN Peptide. Bone morphogenetic protein. Bone regeneration << 4
CIBER-BBN Lipophilic derivatives siRNA. Modied siRNA. Gene therapy << 4
CIBER-BBN Membrane with mesenchymal cells. Osteochondral lesion << 4
CIBER-BBN Targeted delivery carrier. Oncology << 4
LEITAT Protein hydrolysates <<
Company Name Indication Basic R&D Applied R&D
Ready for
exploitation
Available
Technology
transfer in process
Patent
3P BIOPHARMACEUTICALS 3P-BIO Generation of expression systems in bacteria, yeast and mammalian < < < < < < < < < 4
3P BIOPHARMACEUTICALS 3P-TC Development banks crops and human cells for cell therapy < < < < < < < < < 4
3P BIOPHARMACEUTICALS Analytical Biosimilars Platform < < < < < < < < < 4
ABENGOA BIOENERGA Microalgae collection < < < < < < < < <
ALGAENERGY Microalgae Production Technology for several applications < < < < < < < < < 4 4 4
ALGAENERGY Microalgae production facilities, technologies, control and harvesting systems < < < < < < < < < 4 4 4
BIOCHEMIZE PB Screening for microbial and enzymatic biocatalysis < < < < < < < < < 4 4 4
BIOCHEMIZE SC-enz Enzymatic screening for modication of chemical structures < < < < < < < < < 4 4 4
Bioingenium Freedom-to-operate platformin Yeast < < < < < < < < < 4
Bioingenium Freedom-to-operate platformin Bacteria < < < < < < < < < 4
Bioingenium Expression vector with removable resistance gene < < < < < < < < < 4
BIOMEDAL CASCADE Bacterial expression system < < < < < < < < < 4 4 4
BIOMEDAL rProtein A Resins Immunoglobulin capture and purication < < < < < < < < < 4
BIOMEDAL nLZ4 Cost effective ligand for antibody purication < < < < < < < < < 4 4
BIOMOL-INFORMATICS BIOMOL-HTCM In silico drug discovery through combinatorial quimioinformatics < < < < < < < < < 4
BIONATURIS FLYLIFE Baculovirus expression system. MVB, WSVB, upstream development, downstream development, analytical development, scale-up < < < < < < < < < 4 4
BIONATURIS FLYPIDS Recombinant expression of second generation vaccines (VLPs, chimeric, subunits) < < < < < < < < < 4 4
BIONET BIONET Serial 35 L. Bioreactor < < < < < < < < < 4
BIONET BIONET Serial Membrane ltration units < < < < < < < < < 4
BIONET BIONET Fermentation technologies < < < < < < < < < 4
BIONET BIONET Membrane ltration technologies < < < < < < < < < 4
Biopolis Bio-Cpe High added value compounds extraction < < < < < < < < < 4
BIOSEARCH Screenings for antimicrobial, antiobesity, inhibitory of cholesterol absorption activity < < < < < < < < < 4
BIOSEARCH Pilot plant in main food applications. Preparation of dairy prototypes and other food matrices < < < < < < < < < 4
BIOSERENTIA - BIOMASSBOOSTER BMB Genetic Engineering Platformto increase biomass yield - Enhanced Species with overexpressed BMB-707 gene < < < < < < < < < 4 4 4
Curaxys Biosimilars monoclonal antibodies Platform < < < < < < < < < 4
Fundacion MEDINA High throughput screening platformfor microbial extracts with new biotechnological applications < < < < < < < < < 4
Fundacion MEDINA Bioanalysis mass spectrometry platform < < < < < < < < < 4
FUNDACION PROGRESO Y SALUD (SERVICIO ANDALUZ DE SALUD) IMABIS-105 Microplate VacumWasher < < < < < < < < < 4 4
GADEA BIOPHARMA Ps Aseptic lyophilization and lling of APIs < < < < < < < < <
GADEA BIOPHARMA Ps Sterile nal pharmaceutical forms < < < < < < < < <
GAIKER - IK4 Active packaging < < < < < < < < < 4
GAIKER - IK4 Microencapsulation of biosubstances, active ingredients, and essential oils < < < < < < < < < 4
GAIKER - IK4 Incorporation of active substances in textile bers < < < < < < < < < 4
GAIKER - IK4 CO2 Supercritic < < < < < < < < < 4
GAIKER - IK4 Spray-drying < < < < < < < < < 4
GAIKER - IK4 Pyrolisis < < < < < < < < < 4
GAIKER - IK4 Photobioreactor < < < < < < < < < 4
GAIKER - IK4 Biofunctional nanoparticles sintesis < < < < < < < < < 4
GH Genhelix GHL - BIOSIM Biosimilar MABs development platform < < < < < < < < < 4 4
GH Genhelix GHL - PROTO Single use technology application to bioprocesses (Protoplant) < < < < < < < < < 4 4
INGENIATRICS FLOWFOCUSING One step microencapsulation producing small & homogeneous spheres, core-shell, double-shell particles < < < < < < < < < 4 4 4
INGENIATRICS FLOWBLURRING Highly efcient spray of extremely ne droplets production < < < < < < < < < 4 4 4
INGENIATRICS MICROPARTICLES MANUFACTURING Taylored in-plant scaled-up manufacturing < < < < < < < < < 4 4 4
INKEMIA IUCT GROUP GC-SOLV Substitution for green safer solvent fromrenewable resources in diferent industrial applications < < < < < < < < <
INKEMIA IUCT GROUP CG-Bio-GMO Molecular biology: genetically modied microorganism < < < < < < < < <
INKEMIA IUCT GROUP Bio-HTB High throughput biotechnological synthesis of small molecules < < < < < < < < <
INGENIATRICS ONENEB Improved sensitivity and robustness analytic nebulizer and micronebulizer for spectrometry systems < < < < < < < < < 4 4 4
INGENIATRICS NE-4 High troughput nebulizer for material process: drying, pulverisation, etc. Able to operate with highly viscous materials < < < < < < < < < 4 4 4
INGENIATRICS CELLENA User-friendly bioencapsulation portable platformto encapsulate high molecular weight compounds, microorganisms and cells < < < < < < < < < 4 4 4
INGENIATRICS FLOWSPRAY-DRYER Brand-new spray-drying and spray-chilling equipment integrating proprietary technology emitters for highly accurate and efcient microparticles production < < < < < < < < < 4 4 4
INGENIATRICS MICROPARTICLES DEVELOPMENT Customised CRO microencapsulation services for cosmetics, chemicals, consumer goods, Including SPHERES, CORE-SHELL and DOUBLE SHELL structure < < < < < < < < < 4 4 4
INGENIATRICS ATOMIZATION EQUIPMENT / COATING SYSTEMS Development and manufactuing of proprietary technology nebulizers, atomisers, and equipments or devices including it / coating systems < < < < < < < < < 4 4 4
Laboratorios LETI Protein Purication < < < < < < < < < Only special preparations
Lonza Biologics Porrio Stirred bioreactors 5.000 & 10.000 L scale & single-use bioreactors < < < < < < < < < 4
Lonza Biologics Porrio Custommanufacturing of monoclonal antibodies and recombinant proteins using mammalian cell culture < < < < < < < < < 4
MERCK Development of SAM free medium/ MCB,WCB and exCB system < < < < < < < < < 4
MERCK Single use technology application to bioprocesses (USP and DSP) < < < < < < < < < 4
MERCK Analytical support forbioprocess development < < < < < < < < < 4
MERCK DOE for development of bioprocess < < < < < < < < < 4
MERCK Stirred bioreactors bach and feed-bach / (perfusion) < < < < < < < < < 4
MERCK Roller Bottle for mammlian cells < < < < < < < < < 4
MERCK Analytical methods development < < < < < < < < < 4
MERCK Purication of Recombinant Proteins (GMP) < < < < < < < < < 4
MERCK Protein Purication System < < < < < < < < < 4
NEIKER Protein purication < < < < < < < < < 4
NEIKER Development of microalgae culture strategies to obtain high lipid biomass content < < < < < < < < <
PROTEOS BIOTECH PROTEOS-PPS Protein Purication System < < < < < < < < < 4
PROTEOS BIOTECH PROTEOS-MENC Microencapsulation of active ingredients and enzymes < < < < < < < < < 4
PROTEOS BIOTECH PROTEOS-MEM Microemulsication of active ingredients and enzymes < < < < < < < < < 4
PROTEOS BIOTECH PROTEOS-BESE Bacterial expression systemin E. coli < < < < < < < < < 4
SENSIA Biosensor Biomolecular interaction analysis and the presence of chemical compounds < < < < < < < < < 4 Prototype 4
FUNDACION PROGRESO Y SALUD (GENYO) BACM-15 Lentiviral Sistem for the generation of High Producting Clons (Protein Production) < < < < < < < <
Plebiotic PleMD Molecular Dynamics solution < < < < < < < < 4 4
NEIKER Soil micrroorganismdetection < < < < < < < < 4
LAIMAT Microencapsulation, peptides, proteins, essential oils, active principles < < < < < < < 4
LAIMAT Sensors for detection of antibiotics and toxics present in food, clinical toxicology and early diagnosis < < < < < < < 4
BIOMOL-INFORMATICS Generating 3D computer models for bacterial protein polymers as scafolds for nanowires < < < < < <
LEITAT Antimicrobial / antifungal screening < < < < < <
PROTEOS BIOTECH PROTEOS-BESB Bacterial expression system in Bacillus megaterium < < < < < <
LEITAT Protein purication < < < < <
LEITAT Enzyme immobilization < < <
LEITAT Biosurfactant production < <
TECHNOLOGIES
BIOPRODUCTS
Basic R&D 13%
Ready for
exploitation
6%
Industrial scale up 62%
Applied R&D
19%
TECHNOLOGIES
Basic R&D 1%
Ready for
exploitation
90%
Applied R&D 9%


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*Based on data provided by ASEBIO associated companies. APRIL 2013.
Spanish White Biotech Pipeline
*
www. as e bi o. c om
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BIOPROCESSES
Company Name Indication Basic R&D Applied R&D
Ready for
exploitation
Industrial
scale up
Available
Technology
transfer in process
Patent
3P BI OPHARMACEUTI CALS 3P-BIO
New Biological entities (Monoclonal antibodies, recombinant proteins and vaccines) from microbial fermentation
and mammalian cell culture
<<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BIO Biosimilars and Biobetters <<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BI O Process Development/ Optimization (USP and DSP) <<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BI O Analytical methods development and validation <<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BI O Scale up and GMP Production <<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BI O GMP Cell Bank Manufacturing <<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BI O Stability Studies <<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BI O Development of API formulation <<<<<<<<<<<<< 4
3P BI OPHARMACEUTI CALS 3P-BI O API / I MP release <<<<<<<<<<<<< 4
BIOCHEMIZE PB-est Enzymatic and microbial platform for esterication of organic compounds <<<<<<<<<<<<< 4 4 4
BIOCHEMIZE PB-red Enzymatic and microbial platform for reduction of oxygen functional groups <<<<<<<<<<<<< 4 4
BIOCHEMIZE PB-oxi Enzymatic and microbial platform for oxydation of aromatic methylenes <<<<<<<<<<<<< 4 4
BIOCHEMIZE PB-met Enzymatic and microbial platform for methylation of aromatic compounds <<<<<<<<<<<<< 4 4
BIOCHEMIZE PB-rac Enzymatic and microbial platform for separation of racemic compounds <<<<<<<<<<<<< 4 4
BIOCHEMIZE PB-ald Enzymatic and microbial platform for aldolic condensations <<<<<<<<<<<<< 4 4
Bioingenium Fast development of scalable purification processess <<<<<<<<<<<<< 4
Bioingenium Upstream & Downstream development of recombinant proteins bioprocessess <<<<<<<<<<<<<
Biomar Process development and scale-up <<<<<<<<<<<<< 4
Biomar Recovery and purication of natural organic compounds from microbial cultures <<<<<<<<<<<<< 4
BI OMEDAL LYTAG-2nd-PHASE Protein separation and purification <<<<<<<<<<<<< 4 4 4
BI OMEDAL HISTAG-2nd-PHASE Protein separation and purification of histagged proteins in aqueous two phase systems <<<<<<<<<<<<< 4 4 4
Biopolis Bio-Cl Custom cloning and expression of recombinant protein <<<<<<<<<<<<< 4
Biopolis Bio-Snt Biosynthesis of chemical compounds <<<<<<<<<<<<< 4
Biopolis Bio-BPL Process development for biopolymers production <<<<<<<<<<<<< 4
Biopolis Bio-Ctl Bioprocesses / biocatalysis <<<<<<<<<<<<< 4
BIOSEARCH Manufacture and Purication of plant extracts <<<<<<<<<<<<< 4
Curaxys Upstream & Downstream process <<<<<<<<<<<<< 4 4
GADEA BIOPHARMA Biotechnological production of steroids <<<<<<<<<<<<<
GADEA BIOPHARMA Biotechnological production of APIs <<<<<<<<<<<<<
GAI KER - I K4 Contaminated soils bioremediation <<<<<<<<<<<<< 4
GAI KER - I K4 Biological treatments for water purification <<<<<<<<<<<<< 4
GAIKER - IK4 Biopolymers development <<<<<<<<<<<<< 4
GH Genhelix GHL - TT Process development, scale-up, scale-down, and technology transfer of Bioprocesses (USP & DSP) <<<<<<<<<<<<< 4
GH Genhelix GHL - AD Analytical development of bioprocesses <<<<<<<<<<<<< 4
GH Genhelix GHL- PUR Manufacture and Purication of Recombinant Proteins (GMP) <<<<<<<<<<<<< 4
Laboratorios LETI Production of protein extracts / allergens <<<<<<<<<<<<< 4 4
Lonza Biologics Porrio Analytical services and stability studies of DS and DP <<<<<<<<<<<<< 4
MERCK Production of Recombinant Proteins (GMP) (SAM Free mammalian cell culture) <<<<<<<<<<<<< 4
MERCK Production of Monoclonal Antibodies (GMP) <<<<<<<<<<<<< 4
MERCK Manufacturing of mAb and recombinant proteins using mammalian cell culture <<<<<<<<<<<<< 4
MERCK Process development, scale-up, scale-down, and technology transfer of Bioprocesses (USP & DSP) <<<<<<<<<<<<< 4
MERCK Custom manufacturing early clinical stages to commercial supply <<<<<<<<<<<<< 4
MERCK Proces validation and comparability studies <<<<<<<<<<<<< 4
MERCK Analytical services <<<<<<<<<<<<< 4
MERCK Stability studies of DS and DP <<<<<<<<<<<<< 4
MERCK Process development for GMP production (USP ,DSP, QC and QA support) <<<<<<<<<<<<< 4
NEOL BIOSOLUTIONS MICROBIOL Production of single cell oils <<<<<<<<<<<<< 4
PLASMIA BI OTECH Biocatalytic synthesis of nucleoside analogues <<<<<<<<<<<<< 4 4
PRAXIS Proteines & Peptides Micro-nano-formulation, aseptic filling and freeze-drying <<<<<<<<<<<<< 4 4 4
CLEAN BI OTEC Halodepur Biodepuration process of hipersaline wastewater <<<<<<<<<<<<
ALGAENERGY Biomass integral valorization process <<<<<<<<<<< 4 4 4
Biomar Bacterial, fungi and yeasts fermentation <<<<<<<<<<< 4
Biopolis Bio-PHA Process Development for PHA production <<<<<<<<<<< 4
Biopolis Bio-Rp Production and purication of recombinant proteins <<<<<<<<<<< 4
Biopolis Bio-Bph Production of biopharmaceuticas, key organic compounds ans green chemicals <<<<<<<<<<< 4
Fundacin MEDI NA Fermentation of new fungal and bacterial strains with biotechnological applications <<<<<<<<<<< 4
Fundacin MEDINA Isolation of new natural products from microbial fermentations <<<<<<<<<<< 4
GADEA BI OPHARMA Bacterial and fungal fermentation and DSP <<<<<<<<<<<
GAI KER - I K4 Biodetergency <<<<<<<<<<< 4
GAI KER - I K4 Bioremediation <<<<<<<<<<< 4
GH Genhelix GHL - MIC Production of Microbial recombinant proteins <<<<<<<<<<< 4
GH Genhelix GHL - MAM Production of biologicals expressed in mammalian cell lines <<<<<<<<<<< 4
GH Genhelix GHL - VACC Production of biological vaccines through single use equipment <<<<<<<<<<< 4
I NKEMIA I UCT GROUP Bio-SRC Prospection, isolation, charectirezation and performance of new microorganisms in industrial biotechnology <<<<<<<<<<< 4 4
I NKEMIA I UCT GROUP Bio-PROC Substitution of chemical processes for bioprocesses <<<<<<<<<<< 4
NEIKER Production of Recombinant Proteins <<<<<<<<<<< 4
NEIKER Production of Omega-3-Rich Oil from microalgae <<<<<<<<<<< 4
PROTEOS BI OTECH PROTEOS - BFERM Bacterial fermentation <<<<<<<<<<< 4
PROTEOS BIOTECH PROTEOS - PEX Protein expression systems <<<<<<<<<<< 4
PROTEOS BIOTECH PROTEOS - PRP Production of Recombinant Proteins <<<<<<<<<<< 4
X-Pol Biotech X-Pol Biotech Double Switch <<<<<<<<<<< 4
nanoMyP Tiss Series Synthesis of nanostructured tissues for biocatalytic processes <<<<<<<<<<
NEIKER Production of carotenoids from microalgae <<<<<<<<<< 4
Phyture Biotech Development of plant cell cultures as new cosmetic actives ingredients <<<<<<<<<<
PROTEOS BI OTECH PROTEOS-PPMW Proteolytic processes - meat waste <<<<<<<<<<
PROTEOS BI OTECH PROTEOS-PPDA Proteolytic processes - dairy applications <<<<<<<<<<
Bioibrica Biogas production plan project from fat <<<<<<<<<
CLEAN BI OTEC Phytodesal Soil desalination with salt phytoaccumulators <<<<<<<<<
Curaxys Manufacture and Purication of Recombinant Proteins (GMP) <<<<<<<<< 4
Curaxys Production of Monoclonal Antibodies (GMP) <<<<<<<<< 4 4
NEOL BIOSOLUTIONS TRIBIOPLAST Production os biopolymers <<<<<<<<< 4 4
Neuron Bio NST-Pkt Biosynthesis of new poliketides derivatives <<<<<<< 4 4
Phyture Biotech Development of plant cell cultures for dermatologic pathologies <<<<<<<
Biomar I B-Acuicultura Microbial control farms <<<<<<<
LEITAT Bioprocess for textile processing <<<<<<
LEITAT Substitution of chemical processes for bioprocesses <<<<<<
LEITAT Enzymatic improvement of fats and fat valorization <<<<<<
PROTEOS BI OTECH PROTEOS-PPDET Proteolytic proceses - detergents applications <<<<<
PROTEOS BI OTECH PROTEOS-BPEFA Biocatalysis processes - Esssential fatty acids <<<<<
PROTEOS BIOTECH PROTEOS-MBP Microbial biogas production <<<<<
PROTEOS BIOTECH PROTEOS-BS Production of Biosimilars <<<<<
LEITAT Obtention of protein hydrolysates <<<
LEITAT Enzymatic synthesis of prebiotic ingredients <<<
GAI KER - I K4 Development of soil remediation process based on nanoparticles << 4
LEITAT Optimization of anaerobic digestion processes <<
LEITAT Optimization of protein hydrolysates obtaining <<
LEITAT Development of biogas production <<
LEITAT Development of biosurfactant production <<
Phyture Biotech Recombinant proteins production through plant cell cultures platform <
Company Types of Biofuel Raw material
First (1st),
second (2nd)
or third (3rd)
generation
Activity Added value
ABENGOA BIOENERGA Bioethanol Cereal, sugarcane 1st Industrial production Improvement of yields over initial sugars together with high process protability
ABENGOA BIOENERGA Bioethanol Lignocellulosic material, MSW 2nd Development of technologies for industrial production Flagship facility for commercial exploitation of 2G Bioethanol under construction
ABENGOA BIOENERGA Biodiesel Oils 1st Industrial production Production process optimized for Biodiesel production
ALGAENERGY Biomass, biodiesel, bioethanol, biogas Microalgae & cyanobacteria 2nd Laboratory production & genetic engineering Higher yield than 1st generation: No conict with human food. Use of non agricultural land. Grow on either wastewater, brackish water or seawater. Daily harvesting.
BANCO ESPAOL DE ALGAS Biomass, biodiesel, bioethanol, biogas
Microalgae, cyanobacteria (marine, freshwater, brakish
and hypersaline environments)
3rd Fast growing strains, isolation of new species, seelction of strains New biodiversity & cultivation systems, extremphyles, new techniques, connection with pilot plant units at real conditions, and R&D groups.
BIONET Biodiesel, bioethanol, biogas, H2 Fermentative biomass microorganisms 2nd 3rd Equipment supply Engineering services, equipment supply and turn key project
BIOPOLIS Biodiesel, bioethanol, biogas Fermentative biomass microorganisms 2nd Development of optimized microorganisms for biofuels Process optimization
BIOSERENTIA - BioMassBooster Biodiesel, bioethanol, biogas Microalgae 2nd Development of species genetically optimized for efcient production of biomass Signicant yield increase (+260%) in the production of biomass
BIOSERENTIA - BioMassBooster Biodiesel, bioethanol, biogas Higher plants and crops 2nd Development of species genetically optimized for efcient production of biomass Signicant yield increase (+50%) in the production of biomass
BIOMAR Biodiesel Microseaweeds 2nd Strains research and development Integrated processing of the biomass. Viability of the production
Camelina Company Espaa Liquid biofuel Camelina oil 2nd Sustainable 2nd generation feedstock Sustainable 2nd generation feedstock for liquid biofuel processes. Development for aviation liquid biofuel: biojetfuel
Camelina Company Espaa Liquid biofuel Camelina 2nd Sustainable feedstock New sustainable feedstock cultivated in arid dryland regions in marginal and fallow land. Crop productivity increase.
GAIKER - IK4 Biodiesel Oils 1st and 2nd Process improvement, development and testing of new reactions Versatile pilot plant facility
GAIKER - IK4 Biodiesel Animal processing fats 2nd Process improvement Versatile pilot plant facility
GAIKER - IK4 Biodiesel Microseaweeds 2nd Development of the complete process: frommicroseaweed selection to biodiesel producctionPilot plant facilities for the microseaweed culture, ltration, extraction and production of biodiesel
GAIKER - IK4 All All 1st and 2nd Life Cycle Analysis and Life Cycle Costing New tool for the environmental and social evaluation of biofuels
Ingeniatrics All Fuel Delivery Optimised fuel atomization Diminishes emissions - gas and solid particles, makes combustion more efcient. Capacity to make viscous materials burn, e.g. glycerine
Ingeniatrics All Emissions Treatment of NOx Emissions Diminshes NOx emissions utilising urea with improved efciency
INKEMIA IUCT group Biofuels for S-50 diesel engines Glicerol 2nd Development of new biofuels and other biotech products 100% of biomass (oil) use, as it converts glycerin into a biofuel with improved properties compared to famers
INKEMIA IUCT group Heating Glycerol and other 2nd New biofuel for heating in industrial furnances 100% biomass use. Substitutes fuel oils. Economically viable. Does not need preheating of the fuel oils for ignition
INKEMIA IUCT group
Syntehsis and purication of biofuels either by checmial or
biotecnological routes
All 1st and 2nd Process optimization of biofuel production One stop shop for biofuel process optimization
LEITAT All All 1st and 2nd LCA Quantication of the environmental improvements and sustainability of different processes of energy production and biofuels
LEITAT Biogas Organic waste 2nd Process development Process optimization
LEITAT Cogeneration/Heating Biomass 2nd Energy studies Study the technical feasibility of the power source
LEITAT Bioethanol Biomass 2nd Pretreatment of raw material Improvement of the saccharication efciency by chemical or enzymatic pathways
LEITAT Electricity Organic efuents 2nd Microbial Fuel Cells development Obtaining energy from organic waste efuents
LEITAT Biodiesel Oils 1st and 2nd Transesterication process development Recovery of oily waste. More sustainable process
NEIKER Diesel Microalgae 2nd Genetic transformation Process protability increase: mixed use algae
NEIKER Diesel Microalgae 2nd Strains selection Improving farm protability
NEIKER Diesel Microalgae 2nd Biomass production Signicant yield increase in the production of biomass
NEIKER Diesel Crops 1st Crop agronomy Improvement of farm protability
NEIKER Diesel Crops 1st Exploitation and valorization of byproducts Integrated utilization of biomass: energy and animal feed
NEIKER Biogas Organic waste 2nd Biomethanization process improvement Recycling organic wastes to generate methane processes
NEIKER Biogas Microalgae 2nd Biomass production Technical feasibility study of the power source
NEIKER Cogeneration Organic waste 2nd Digestatos Treatment Technical feasibility study of digestate in agriculture
NEIKER Cogeneration Organic waste 2nd Nutrients removal Increased protability of processes through a combination of different organic sources
NEIKER Gas heating Biomass 2nd Improvement of biomass production systems Reduced costs of intensive agricultural production systems: energy efciency of production processes
Neol BioSolutions Biofuels Raw gliceryn; lignocellulose biomass 2nd MicroBiOil(Production of renewable biofuels) Valorisation of by-products. High yield production of single cell oils
PIONEER HI-BRED Biodiesel Oil Crops (Sunower and Rape) 1st Development of improved varieties Sunower and rapeseed hybrids with higher levels of fatty acids and yield per unit area, adapted to specic agricultural conditions in Spain
PIONEER HI-BRED Bioethanol Crops (Corn and Sorghum) 1st Development of improved varieties Corn hybrids with higher starch content and extractable per unit area production adapted to specic agricultural conditions in Spain
PIONEER HI-BRED Biomass Crops (Corn and Sorghum) 1st Development of improved varieties Hybrids of maize and sorghumforage with high production capacity of dry matter per unit surface area adapted to specic agricultural conditions in Spain
PIONEER HI-BRED Biogas Crops (Corn and Sorghum) 1st Development of improved varieties Hybrids of maize and sorghumforage with high production capacity of dry matter per unit surface area adapted to specic agricultural conditions in Spain
PIONEER HI-BRED Biogas Fermentative biomass bacteria 2nd Development of specic starins Strains of Bacillus spp. With a high generation capacity of lactic acid for the preservation of forage and cell lysis capacity for a more effective capacity in anaerobic digestion
REPSOL Biofuels Oil crops (Jatropha) 1st Production of biomass Valorization of biomass
REPSOL Biofuels Microalgae 3rd Development of technologies for industrial production Improvement of the culture and downstream processes. Viability of the production.
REPSOL Biofuels Lignocellulosic material 2nd Development of microorganisms and optimization of biofuel production Synthetic biology approach for new biofuel precursor molecules production
BIOFUELS
BIOPROCESSES
Ready for
exploitation 26%
Basic R&D 6%
Applied R&D 17%
Industrial
scale up 51%