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Northwestern Medical Review, Biochemistry Review Notes, Answer Key, 2005


Supplement And Answer Key
Biochemistry Review Notes: With Relevant Pathology and Pharmacology

Page Notes
15 Iron-related Questions:
Absorption: Ferrous Form
Transportation: Transferrin (Ferric)
Storage: Ferrritin
Deposit in Tissue: Hemosiderin (Iron, protein
and polysaccharide)
Commonly tested concept: hemochromatosis
15 Multiple Choice [E]
15 Rate limiting enzyme is phosphofructokinase I
16 DHAP is the common compound between fats
and sugars
17 Multiple Choice [A]
17 Glycolysis takes place in Cytoplasm
18 Multiple Choice [E]
20 Glucokinase is the only glycolytic one found in the
liver
20 Commonly Tested: Glucose 6-Phosphatase
20 Commonly tested enzyme in glycolysis: Pyruvate
dehydrogenase
21 Multiple Choice [A]
22 Multiple Choice [B]
22 Glycerol
22 Multiple Choice [E]
23 Lipoic Acid
23 Alpha-ketoglutarate of TCA
24 Multiple Choice [B]
24 Multiple Choice [B] and [C]
24 Isoleucine
27 Multiple Choice [E]
27 Who am I: Nitroprusside
27 Matching: 1B, 2C, 3A, 4D
29 Multiple Choice [B]
30 Multiple Choice [D] and [E]
31 Andersens
31 Who am I: Alcohol
32 Multiple Choice [A]
32 Multiple Choice [C]
33 Ethanol
Nerve II (CN II)
Metabolic acidosis with increased anion gap
33 Who am I: Korsakoffs
33 Who am I: Delirium tremens
34 Anterograde amnesia
Retrograde amnesia
Confabulation
34 Multiple Choice [B]
35 Who am I: Nitrofurantoin
36 ExceptG6PD
36 Multiple Choice [A]
36 Multiple Choice [B] and [C]
38 Multiple Choice [C] and [D]
42 Heparan
Hyaluronic acid
Keratan sulfate
42 Multiple Choice [A] and [B]. Most likely he has
Hunters
43 ...Except...Hunters
46 Required for formation of arachidonic acid
48 Hypo
Autoimmune and/or Iodine deficiency
Yes there is
50 Type II
50 Type II and III
50 Multiple Choice [A]
52 Multiple Choice [B]
55 Multiple Choice [C]
56 Multiple Choice [D]
58 Multiple Choice [C]
58 Type II
Lovastatin
60 Multiple Choice [B] and [E]
60 And Niemann-Pick
61 Fabrys (X-linked)
61 Tay-Sachs
62 Multiple Choice [D] and [A]
62 Multiple Choice [A]
63 Multiple Choice [E]
63 Matching: see the pre-test answer key in your
textbook
68 Multiple Choice [C]
68 Megaloblastic (B12 deficiency)
69 Porphyria Cutanea Tarda (PCT)
PCT
PCT and Congenital Erythropoietic
69 Multiple Choice [C]
69 Multiple Choice [D]
70 Lead Poisoning (non-genetic cause) and Acute
intermittent
70 See your books answer key
72 Multiple Choice [C]
72 Normo
73 Multiple Choice [A]
73 Multiple Choice [D]
73 See the books answer key for the matching
75 Multiple Choice [C]
78 Multiple Choice [A]
79 Multiple Choice [D]
81 Multiple Choice [E]
82 Multiple Choice [D]
82 Multiple Choice [A]
83 Multiple Choice [B]
84 Multiple Choice [D] and [A]
85 See the answer key in your book for the matching
85 Multiple Choice [D]
86 Multiple Choice [E]
92 See the answer key for the matching in your book
92 Multiple Choice [A]
95 Multiple Choice [C]
95 Multiple Choice [B]
96 See the answer key for the matching in your book
99 Multiple Choice [C]
99 Multiple Choice [A]
100 Thiamine
102 ALS
103 B12 that accumulates in the liver
103 Folate deficiency
104 Multiple Choice [D]
2. Northwestern Medical Review, Biochemistry Review Notes, Answer Key, 2005
104 Multiple Choice [A]
105 Vitamin E
Vitamin D
Liver
Fat mal-absorptive conditions: Biliary obstruction,
Liver disease, Celiac, cancer of pancreatic head,
etc.
106 Multiple Choice [B]
109 Trousseaus sign of hypocalcemia
Facial muscle spasm after tapping facial
nerve, sign of hypocalcemia
Dantrolene
109 Active osteoblasts & osteoclasts
Abnormal regional (around pagetic tissue)
bone growth & softening, and Osteoarthritis
Hearing loss.
High
Man
Pami or etidronate
Inhibit osteoclastic activity. Reduce both
resorption and hydroxyapatite formation!
Ethacrynate (loop diuretic)
No Thiazides can be adminsteresd
Etodolac (An NSAID)
Calcitonin
PliCamycin
Hypercalcemia. Large dose of
glucocorticoids antagonize effect of active
vitamin D, and slow absorption of GI calcium
and increase renal secretion. Predispose to
osteoporosis.
Summary: Pamidronate & etiodronate;
Ethocrynic acid & furosemide (loop
diuretics); Etodolac; Plicamycin; Calcitonin;
Prednisone (glucocorticoids)
112 Multiple Choice [E]
113 Multiple Choice [B]
116 Multiple Choice [A]
116 Multiple Choice [B]
118 Multiple Choice [A]