Professional Documents
Culture Documents
develop on their own terms, unfettered trative staff. From the macro—keeping
Dean’s Message
Net gains:
A typical setup for a sensor network consists of numerous small,
low-powered, wireless “motes” (specially designed data collectors
from microphones to pulse monitors). Each device, smaller than a bar
of hotel soap, has limited computation, sensing, and communication
abilities. But when properly networked and supported with the right
software, the system can gather and transmit a wealth of informa-
tion—such as the rumblings of an active volcano or the rhythm of a
patient’s heart—to a central hub such as a laptop or PDA. We hope
our “sensor net” of information gives you a glimpse into some of the
exciting activities and connections emerging at the Division.
Pierce Hall
Pierce Hall, the red brick centerpiece built in 1901, has
undergone extensive renovations this summer and fall.
The third floor has been remodeled to make room for
more offices to accommodate new hires in applied math-
ematics and bioengineering. Over the next year, the first
and second floors will undergo a similar transformation
with the additional aim of creating instructional labs. The
third-floor space that currently houses the Gordon McKay
and Blue Hill libraries may also be reassessed to provide a
more functional design without limiting services. J
New arrivals
The Division is pleased to welcome five new faculty
members this fall. To see complete research profiles
of the Division’s new faculty and extensive bios of all
members, visit: www.deas.harvard.edu/directory
David J. Mooney
Mooney Gordon McKay Professor of Bioengineering
Background: B.S. (1987) in Chemical Engineering,
University of Wisconsin at Madison; Ph.D. (1992) in
Chemical Engineering, Massachusetts Institute of
Technology, Postdoctoral Fellow, Harvard Medical
School (1992–1994). Before coming to the Division,
Mooney spent ten years conducting research and
teaching at the University of Michigan.
Areas of Focus: Biophysics; biomechanics; cell and
tissue engineering
Radhika Nagpal
Assistant Professor of Computer Science
Wolfe
Background: S.B. and S.M. (1994) and Ph.D. (2001) in
Electrical Engineering and Computer Science,
Massachusetts Institute of Technology. Before coming
to the Division, Nagpal spent a year as a research
fellow at the new Department of Systems Biology at
Harvard Medical School.
Areas of Focus: Distributed and multi-agent systems;
biologically inspired programming paradigms;
systems biology
Patrick J. Wolfe
Assistant Professor of Electrical Engineering
Background: B.S. (1998) in Electrical Engineering
and B.Mus. (1998), University of Illinois at Urbana-
Champaign; Ph.D. (2003) in Engineering, University
of Cambridge (U.K.)
Areas of Focus: Communications and signal processing;
stochastic systems
Crozier
Todd Zickler
Assistant Professor of Electrical Engineering
Background: B.Eng. (1997) in Electrical Engineering,
McGill University (Montreal, Canada); M.S. (2001) and
Ph.D. (2004) in Electrical Engineering, Yale University
Nagpal
Nagpal
Areas of Focus: Computational vision and control J
Selected articles
about the Division
for these particles to fall far enough to
adversely impact pressure within the
inner ear roughly matches the typical
lapse between a head tilt and onset of
vertigo.”
Along with Harvard undergraduate
(now GSAS graduate student) Michael S.
Weidman, Todd M. Squires at Caltech,
and Timothy C. Hain of Northwestern,
Stone examined whether this delay
An overview of the types of monitoring
might coincide with the movement equipment—including boats, planes, and
of otoconia. Hain, a medical scientist satellites—used to conduct air quality stud-
ies in North America and western Europe
who studies motor control of the head in the summer of 2004. (Figure courtesy of
Displaced tiny particles in the inner ear
(called otoconia) are believed to collect in
and neck, originally sought Stone’s as- ICARTT.)
the back of the canals and cause a common sistance in studying the possible role
form of vertigo. (Figure courtesy of Timothy
of fluid dynamics in BPPV. Stone says Christian Science Monitor that the work is
C. Hain, Northwestern University.)
that he, Squires, and Weidman, none of critical to setting emissions standards,
whom are physicians, bring a different “otherwise, you could find that your
Rethinking vertigo perspective to a medical ailment that’s efforts are being defeated by ozone
A team of engineers and physicians from largely mechanical in nature. In addi- pollution from somewhere else.”
Harvard University, the California Insti- tion, Stone and his collaborators can Scientists conducted research on all
tute of Technology, and Northwestern provide other quantitative insights use- fronts—land, sea, and air—to provide
University developed a mathematical ful for characterizing BPPV. unprecedented information about the
model to support a new theory on the “Because of its mechanical nature, BPPV air as it crosses the United States, leaves
cause of benign paroxysmal positional may be an illness that requires a degree New England, traverses the Atlantic
vertigo (BPPV), the most common form of cooperation between physicians and Ocean, and arrives in western Europe.
of vertigo. engineers,” Stone says. Among the U.S. partners were Harvard
BPPV is a mechanical disorder origi- Adapted from the Harvard University University, the Department of Energy,
nating in the vestibular system within Gazette, August 9, 2004 Brookhaven National Laboratory, and
the inner ear, where three fluid-filled the California Institute of Technology.
semicircular canals detect head rota-
tion about each of three axes. Many re-
Sampling the summer air The Meteorological Service of Canada
and European scientists with the
searchers believe that BPPV attacks are Hundreds of government and university Intercontinental Transport of Ozone
triggered when calcite particles called scientists from across the country and and Precursors–North Atlantic Study
otoconia, which normally reside in the in western Europe, including the Divi- also collaborated.
inner ear, dislodge and interfere with sion’s Daniel Jacob, sampled the quality
of the air this summer in the largest air Adapted from information supplied by
proper functioning of these semicircu-
quality and climate study to date, as part NOAA, June 28, 2004.
lar canals.
of the International Consortium for At-
“While BPPV is not life-threatening, it
mospheric Research on Transport and Exploring the origins
induces disorientation that is severely
discomforting and can cause nausea
Transformation (ICARTT). The National of life
Oceanic and Atmospheric Administra-
and accidents,” says Howard A. Stone, Scot Martin, Gordon McKay Professor of
tion (NOAA) and NASA were co-leads of
Harvard College Professor and recently Environmental Chemistry, and a group
the endeavor, which began in early July
named Vicky Joseph Professor of Engi- of Division and Harvard collaborators
and ended in August.
neering and Applied Mathematics. “We including Xiang Zhang, Henrich Hol-
used hydrodynamic models to show A special focus of the sampling is a com- land, Cynthia Friend, and Martin Schoo-
that if tiny particles in the inner ear prehensive effort to characterize air nen (SUNY–SB) presented “Mineral
become dislodged, which researchers quality in New England. The research Photoelectrochemistry as an Efficient
have previously posited as the trigger will help provide the solid science Pathway for Prebiotic Synthesis” as
for BPPV attacks, the period of time needed to underpin the region’s efforts part of the American Chemical Society
to improve air quality. Jacob told the
Information exchange
between quantum dots
Scientists at Harvard have found that
the fundamental elements of a quantum
computer can exchange information
and work in tandem even when they’re
separated by a considerable distance.
The result represents the first success
A silicon nanowire (blue) is crossed by three
at controlling the transfer of informa- nanowires of a different composition (top).
(ACS) meeting held in Philadelphia on tion between quantum particles located
some distance apart, rewriting the belief today’s integrated circuits, are so much
August 22–26, 2004.
that “quantum dots” must be neighbors bigger than the nanowires. This is the
In lay terms, the research team looked first time that bridging two different
to operate in unison, and advancing
at how life started on earth. Carbon types of materials has been done at the
scientists’ progress toward developing
fixation, which is the conversion of nanometer level.
massively parallel spin-based quantum
inorganic carbon sources into organic
computing. Quantum computing’s Adapted from the Harvard University
molecules, is an important step in the
practical value would be severely lim- Gazette, July 22, 2004. Articles also ap-
origin of life. The team’s work addresses
ited if only neighboring dots were able peared in Nature News and Chemical &
the possibility of a new reaction path-
to correlate their spins. Engineering News
way based on solar irradiation and the
photoelectrochemical properties of Adapted from the Harvard University
metal sulfide minerals. Chemical evolu- Gazette, August 9, 2004 Virus detectors
tion is the first stage, before Darwinian Harvard University scientists have
evolution; at this stage, chemical reac- Quantum network found that ultra-thin silicon wires can
tions that transform inorganic materi-
als such as CO2 into organic molecules
goes live be used to electrically detect the pres-
ence of single viruses, in real time, with
play an important role. These reactions In collaboration with Harvard Univer- near-perfect selectivity. These nanowire
are often slow and need external energy sity and Boston University, BBN Tech- detectors can also differentiate among
input, such as electric discharge or ther- nologies announced that it has built the viruses with great precision, suggesting
mal energy. The research findings dem- world’s first quantum cryptography net- that the technique could be scaled up to
onstrate an efficient pathway for these work and is now operating it continu- create miniature arrays easily capable of
reactions via solar energy and minerals. ously beneath the streets of Cambridge. sensing thousands of different viruses.
Today the DARPA Quantum Network
Adapted from information supplied by In a clinical setting, the extreme sensi-
links BBN’s campus to Harvard Univer-
the ACS J tivity of nanowire arrays means they
sity; soon it will stretch across town to
could detect viral infection at very
include Boston University.
early stages, when the immune system
Adapted from the Harvard University is still able to suppress virus popula-
Gazette, August 2, 2004, and a BBN tions. It’s at this stage of viral activity
Technologies press release that symptoms often begin to appear,
How did life begin? Scot Martin and other but with viruses still present in limited
“astrobiologists” are trying to go back in
time (about four billion years) by recreating
Nanowires and switches numbers, they can be difficult to detect
the conditions that may have led to life on Harvard scientists have taken the first and treat. While there are many ways
earth. for researchers to assay viruses, most
step toward making chips with billions
instead of millions of components, nano- are laborious and appropriate only in
electronics instead of microelectronics, laboratory settings. The use of nano-
making wires as thin as 3 nanometers, wires provides immediate verification
tens of atoms thin. What’s more, the of a given virus’s presence without any
nanotechnologists have built switches specialized biochemical manipulation.
right into the wires, solving the tedious Adapted from a September 22, 2004, press
problem of connecting the switches, release prepared by the Faculty of Arts and
amplifiers, and other devices that, in Sciences Office of Communications J
by Fred Abernathy, Abbott and James Lawrence Professor of “I believe that the overall concept of ‘What is engineering?’ is
Engineering and Gordon McKay Professor of Mechanical Engi- quite critical and is not well addressed by the media or even
neering, and Woodward Yang, Professor of Electrical Engineer- within our own academic community. Some professional
ing and Computer Science, the capstone course challenged engineering societies are in fact struggling with ways to edu-
students to envision a “2.0 version” of the Gordon McKay-Blue cate the overall population and improve the popular image of
Hill libraries perched on the third floor of Pierce Hall. engineers,” says Yang. “I think the description of engineering
as ‘solving technical problems in the real world based on
“Young people have grown up in the digital age,” says Aberna- real constraints’ is an important distinguishing feature of
thy. “They understand the convenience of digital searches and engineering and summarizes quite well what we are trying to
they tried to bring some digital search capability to the Gor- teach in ES96.” J
don McKay Library.” Students worked closely with the library
Their assignment dramatically reduced.” Not 24 hours through library current subject-title-au-
Devise a practical and surprisingly, journals and loan services. Amazingly, if thor limitation of Harvard’s
elegant scheme to better books take up much of the the Division went through online system. All the scan-
use/reallocate library space room in the library. Rather with the students’ plans, ning could be done on-site
and enhance services for than figuring out a clever linear shelf space could and cheaply without bump-
Division members while scheme for how best to be reduced by 50 percent. ing up against copyright
considering the needs of stack the racks, students Further, by counting the issues.
the library itself, including investigated what on-site number of visitors and vid- The second solution, an
its present staff, obligation publications were the most eotaping the use of study Article Delivery Service al-
to Harvard, and role in the used. In the case of jour- tables, the students sug- ready used by schools such
wider community. And, of nals, it turned out that two gested a more modular and as Princeton, would provide
course, stay within a rea- percent of titles accounted space-saving design that easy access to virtually
sonable budget and do not for almost 60 percent of better reflected actual use. any journal article online.
violate publisher copyright citations. Combining this To ensure functionality Faculty and students would
laws. Give up? knowledge with other despite the reduced space, gain quick access to a
usage data, the students the team suggested aug- locally scanned online ver-
Their solution recommended potentially menting the library’s Web sion of a requested article
In their nearly 350-page reducing the 1,200 current site and virtual offerings via e-mail. To preserve
final assessment, the journal subscriptions to the to provide more service the copyright obligations,
students concluded, “It’s 550 most-used. (especially outside of the restricted file access would
the balance of physical Similarly, based on check- physical library environs), be maintained through
space and digital space out rates, the students and introduced two novel password protection.
that allows us to make the determined that current digital enhancements. The Division plans to fur-
recommendations that will books could be reduced Digibook, a new kind of ther review how to enhance
keep users of the Gordon from 5,864 to 2,749. The browsing, would offer easy the libraries, and in the
McKay library from feeling remainder could be moved access to digital versions of process consider some of
a decrease in accessibility to the Harvard repository the tables of contents and the suggestions from the
and functionality when the for archival purposes and indices of books, enabling ES96 project.
floor space of the library is still be accessible within users to search beyond the
The sensor nets are packed inside plastic A relay antenna is used to bounce signals down Tungurahua has a reputation for erupting with
casings for protection. the mountain to the base camp below. more than just research opportunities.
The Case Family Foundation on behalf of Bob Case A.B. ’76, M.B.A. and Date: December 5, 2004
J.D. ’79, and Susie Case A.B. ’79, S.M. ’79, M.B.A. ’83, endowed the Robert Registration and information:
and Suzanne Case Professorship www.complexfluids.org/necf/index.php
Jean E. de Valpine A.B. ’43, J.D. ’49 endowed the Lola England Professorship ....................................
George Joseph A.B. ’49 endowed the Vicky Joseph Professorship Holiday Lecture: Polymer
Allen E. Puckett S.B. ’39, S.M. ’41 endowed the Allen E. and Marilyn M. Puckett Playground, presented by
Professorship Howard Stone
Jeff C. Tarr A.B. ’66 endowed the Tarr Family Professorship Date: December 11, 2004
Last year, Stone presented,
Innovation Funds for Engineering and Applied Sciences “A Peek at Printing: From Papyrus
John A. Armstrong A.B. ’56, A.M. ’61, Ph.D. ’61 and Elizabeth S. Armstrong A.B. ’58 to Electronic Paper.”
created the John A. and Elizabeth S. Armstrong Innovation Fund ....................................
David B. Heller A.B. ’89 created the David B. Heller Innovation Fund Industrial Outreach Program
William Laverack Jr. A.B. ’79, M.B.A. ’85 and Cordelia Reardon Laverack created 2005 Workshop
the Laverack Family Innovation Fund
Planning for the 2005 workshop is
Thierry G. Porté A.B. ’79, M.B.A. ’82 created the Thierry G. Porté Innovation Fund under way. Watch the Division site
Gary M. Reiner A.B. ’76, M.B.A. ’80 created the Reiner Family Innovation Fund for exact dates and further details.
James F. Rothenberg A.B. ’68, M.B.A ’70 created the James F. Rothenberg
Innovation Fund
William A. Shutzer A.B. ’69, M.B.A. ’72 created the William A. and Fay L.
Shutzer Innovation Fund Innovate with us
Richard W. Smith A.B. ’74 created the Porthcawl Innovation Fund We encourage Division graduates
to get involved with the Industrial
Edward A. Taft III A.B. ’73 created the Edward A. Taft III Innovation Fund Outreach Program (IOP). Share your
An anonymous alumnus on the Class of 1968 created an Innovation Fund insights with us and learn about our
latest discoveries and opportunities
Room for growth firsthand.
IOP recently held its third workshop in
We are also pleased to report that a room in Maxwell Dworkin, which houses the spring, “Frontiers in Materials and
faculty in computer science and electrical engineering, has been named in Nanoscience.” In late October its sister
recognition of the generosity of two donors. group, the Harvard Industrial Partner-
ship (HIP), hosted its meeting on the
MD 123 is now the William Andrew Danoff ’82 and Ami Kuan Danoff ’84 Room. influence of computing and technology
on society. To learn more about IOP,
Find out more see www.deas.harvard.edu/industry
or contact
For more information about the Challenge Fund or other gift opportunities,
see www.deas.harvard.edu/alumni/challengefund.html or contact Fawwaz Habbal
Associate Dean for Research
Lisa Boudreau and Planning
617-495-5829
Director of Development and Corporate Relations
industry@deas.harvard.edu
617-495-4044 or lisa_boudreau@harvard.edu J
The beauty of
basic research
An ongoing series of photo essays
dedicated to showcasing how DEAS
inspires collaborative work and
encourages interdisciplinary research.
T
2 he images portrayed at left provide an aesthetic
and scientific perspective on some of the research
undertaken by our faculty and students.
Engineers and scientists increasingly rely on so-
phisticated imaging, manipulation, and fabrication
techniques to investigate problems.
1 3 4 By “seeing” more, researchers can better understand
the basic properties of our world and translate what
they discover into everyday technologies and
applications—from novel microchip design to next-
generation medical devices. J
1. A light-conducting silicon wraps a beam of light
6 7 around a strand of human hair. Courtesy of L.
Tong and E. Mazur.
2. Complex microfluidic channels are created with
soft lithography techniques. Courtesy of D. Weitz.
3. Microfabrication techniques lead to new types of
structures and novel materials. Courtesy of
G. Whitesides.
4. These colorful rock-like patterns are actually
5 8 9 elemental maps taken with an Energy Dispersive
X-ray Spectroscopy System. Courtesy of CIMS.
Feedback loop 5. An invasive glioblastoma cell (a tumor) remodels
We welcome and appreciate your the fibers of a gel matrix surrounding it. Courtesy
comments, suggestions, and of V. Gordon, E. Filippidi, and L. Kaufman.
corrections. Please send feedback to 6. Waves injected into two resonators in a two-
communications@deas.harvard.edu dimentional electron gas (2DEG) emerge through
or call us at 617-496-3815. This openings in the cavities. Courtesy of E. Heller and
newsletter is published biannually by: R. Westervelt.
The Division of Engineering and Applied
7. A slurry of small particles that oscillate up and
Sciences Communications Office
down and form into a crown. Courtesy of H. Stone
Harvard University and Johann Schleier-Smith (a former Harvard
Pierce Hall undergraduate).
29 Oxford Street 8. Both water-in-oil-in-water (w/o/w) emulsions
Cambridge, MA 02138 and the inverse (o/w/o) form drops within drops.
Managing Editor/Writer: Courtesy of D. Weitz.
Michael Patrick Rutter 9. Concentrated suspensions of particles with a poly-
Designer, Producer, Photographer: mer present in the solution behave like pastes.
Eliza Grinnell Courtesy of D. Weitz.
This publication, including past issues, 10. Two- and three-dimensional patterns of drops
is available on the Web at emerge when microfluidic channels widen. Cour-
www.deas.harvard.edu tesy of G. Crisobal-Azkarate.
11. Nearly perfect packing of nanoparticles caused by
Copyright © 2004 by the President
the surface tension of a liquid. Courtesy Manouk
and Fellows of Harvard College 0 Abkarian, Janine Nunes, and David Bell.
12. An air bubble covered by polystyrene particles.
The particles adhere readily to the bubble inter-
face due to the salt present in the water.
Courtesy of R. Larsen.
13. Spherical shells of micron-sized particles can
be formed by introducing colloidal (a gel-like mix-
ture) particles to emulsion droplets. Courtesy of
M. Brenner, D. Nelson, and D. Weitz.