SKELETAL AND IMMUNE SYSTEM QUIZ

1. An intravenous infusion causing a
sharp rise in the blood level of
calcium will most likely result in:
a. Increased osteoclast activity,
raising the blood level of
calcium.
b. increased osteoclast activity
lowering the blood level of
calcium.
c. increased osteoblast activity
lowering the blood level of
calcium.
d. increased osteoblast activity,
raising the blood level of
calcium.
2. Compared to the bones of an adult,
the bones of a growing child:
a. show areas of cartilage in the
long bones.
b. have more Haversian canals.
c. have fewer osteoblasts.
d. are more dense.
3. The majority of the MHC class II
molecules on the surface of a cell
infected with a bacterium will have
bound peptides that are derived
from:
a. Killer T cells
b. The bacterium
c. The host cell
4. Which of the following statements
is true regarding activated B cells?
I.
Activated B cells contain more
rough endoplasmic reticulum
than activated T cells
II.
Activated B cells contain more
lysosomes than macrophages
III.
Activated B cells contain no
nucleus
a. I only
b. II only
c. I and II only
d. I and III only
5.
6.
7.

8. Which of the following is not a
nonspecific immune defense?
a. Hydrochloric acid produced
by the gastric glands
b. Lysozyme in tears
c. Intact epidermal cells
d. Production of antibodies
9. Which of the following statements
best describes the difference
between the humoral response and
the cellular response?
a. The humoral response is a
specific immune response
while the cellular response is
nonspecific.
b. The cellular response is
directed against pathogens
that have entered body cells,
while the humoral response
is directed against free
floating antigens.
c. Only the humoral response
results in immunological
memory.
d. The cellular response
involves the production of
antibodies while the humoral
response does not.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.

Skeletal and Immune System Quiz 1

Viral proteins are recognized as "self". Abnormal cells that could potentially turn cancerous possess molecular markers that are not found on normal cells. Abnormally high osteoclast activity d. Myasthenia gravis is a neuromuscular disease that researchers believe is caused by an autoimmune reaction in which antibodies are produced against the acetylcholine receptor in the neuromuscular junction after a viral infection. naturally acquired active immunity. 22. and antibodies produced against the virus cross-react with the acetylcholine receptor d. 25. Helper T cell 24. Once identified by the immune system. Over reduction of calcitonin c. Which type of immune cell is responsible for destroying these abnormal cells? a. and antibodies produced against the virus do not cross-react with the acetylcholine receptor. c. b. Abnormally high osteoblast activity 27. artificially acquired active immunity. c. B cell b. and antibodies produced against the virus do not cross-react with the acetylcholine receptor. Which of the following statements provides the best explanation of the cause of autoimmune myasthenia gravis? a. The transfer of antibodies from one individual who is immune to a particular disease to another individual who is not immune to that disease is an example of: a. 23.20. Toxic T cell c. A chronic dietary deficiency in calcium would have the same effect on bone structure as which of the following abnormalities? a. Underproduction of parathyroid hormone b. Viral proteins are recognized as "non-self". d. Suppressor T cell d. 21. these cells are destroyed. and antibodies produced against the virus cross-react with the acetylcholine receptor b. Artificially acquired passive immunity 26. 29. Viral proteins are recognized as "non-self". 28. Skeletal and Immune System Quiz 2 . naturally acquired passive immunity. Viral proteins are recognized as "self".

so choice (B) can be eliminated. so statement II is false. 4. lysozyme found in tears.) Only statement I is correct. not lower it. The primary function of activated B cells is to produce antibodies to be secreted. An important task of the immune system is to identify "self" vs. and not the correct answer. since osteoblasts are responsible for building bone. Choice (D) can be eliminated since it is a false statement: an increase in osteoblast activity would lower the blood level of calcium. Choice (D) is the correct answer. so choice (A) can be eliminated. The cells that function in calcium homeostasis are the osteoclasts and osteoblasts. Choices (B) and (C) are therefore incorrect. Statement I must be part of the correct answer. VIII. 3. not raise it. while the cellular response is directed against pathogens that have entered body cells. "non-self" cells and destroy "non-self" cells while leaving “self" cells unharmed. Macrophages would have a greater number of lysosomes than activated B cells. while the bones of an adult would not. 6. the body will work to lower the calcium level in order to maintain homeostasis. In this case. so choice (A) is false. These polypeptide fragments are then displayed by the MHC class II molecules on the surface of the cell. IX. 7. eliminating choice (D). Choice (A) is the correct answer. V. 2. Choice (C) is incorrect since the bones of a child would likely have more osteoblasts than an adult. the body works to lower the blood level of calcium. If there is a sharp rise in the blood level of calcium.IV. releasing calcium into the blood. Choice (C) is the correct answer. since increased osteoclast activity would raise blood calcium. since the humoral response involves the production of antibodies. Choice (B) is true. and the correct answer: the humoral response is directed against antigens that have not yet entered body cells. Choice (C) is incorrect. VI. Choice (B) can be eliminated since it is a false statement: an increase in osteoclast activity would raise the blood level of calcium. the pathogen is broken down into polypeptide fragments. Thus. (Mature erythrocytes have no nuclei. composed of cartilage. Choice (B) is incorrect since the bones of a child would not necessarily have more Haversian canals than those of an adult. removing calcium from the blood. so choice (D) is the correct answer. Macrophages are specialized cells that engulf bacteria and dead cells via phagocytosis and destroy the cellular material via digestive enzymes and reactive forms of oxygen. SKELETAL & IMMUNE SYSTEM ANSWER KEY 1. The epiphyseal plate. X. Both the humoral response and the cellular response are specific immune responses. while activated T cells do not have as much of a secretory role. Choice (D) is incorrect. VII. since the rough ER is the cellular organelle responsible for the production of secretory proteins. The bones of a growing child would show areas of cartilage. When a pathogen is ingested b y a macrophage. Choice (D) is false. Recall that osteoclasts break down bone. since if the immune . since the bones of a child would not necessarily be denser than those of an adult. Activated B cells do contain nuclei. Insulin acts to decrease blood glucose levels while glucagon increases blood glucose level. Antibodies are composed of 4 protein subunits. because both the humoral response and the cellular response result in the formation of memory cells. Choices (A) and (B) can be eliminated. Intact skin. activated B cells would contain more rough endoplasmic reticulum. The production of antibodies is part of the specific immune defense. Nonspecific immune defenses constitute the first line of defense against infection. while osteoblasts build bone. Choice (B) is the correct answer. and hydrochloric acid produced by the gastric glands are all nonspecific immune defenses. so statement III is false. Choice (A) is the correct answer. 5. is the site of longitudinal growth in long bones. and choice (A) is the correct answer.

In a person who does not produce sufficient parathyroid hormone. Recall that the function of osteoclasts is to break down bone. cytotoxic T cells destroy infected cells and cancer cells. damaging the receptor. Calcitonin lowers blood calcium levels by inhibiting the release of calcium from bone. By Test Day. Cytotoxic T cells are responsible for destroying potentially cancerous cells. suppressor T cells regulate the activity of B and T cells. but antibodies produced against the virus also react with the acetylcholine receptor. so choices (A) and (C) are incorrect. 9. B cells produce antibodies. so choices (A) and (B) are incorrect. so choice (C) is the correct answer. This leaves choice (D).system (erroneously) identifies the viral proteins as "self'. Naturally acquired immunity involves the passage of antibodies from mother to fetus. resulting in a lower mineral content in the bones. so choice (A) is incorrect. This is the same effect that a chronic dietary deficiency in calcium would have. it is a type of passive immunity. and helper T cells activate B and T cells. Abnormally high osteoblast activity would result in a building up of bone. then no autoimmune disease results. . which is the correct answer. If the activity of osteoclasts is abnormally high. Choice (C) represents a possible explanation for the cause of myasthenia gravis: the immune system correctly identifies the viral proteins as ‘non-self’. calcium will be released from the bones. calcium is maintained in the bones. so choice (B) is the correct answer. you should be familiar with B and T cells and know their functions. choice (C) is the correct answer. 10. Choice (D) is incorrect because if the antibodies produced against the viral proteins do not cross-react with the acetylcholine receptor. Again.no antibodies will be produced against the viral proteins. 8. so choice (B) is incorrect. so choice (D) is incorrect. Parathyroid hormone raises the blood level of calcium by stimulating calcium release from bone. Since this type of immunity results from the transfer of antibodies.